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propranolol and nisoldipine

propranolol has been researched along with nisoldipine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's9 (33.33)18.2507
2000's4 (14.81)29.6817
2010's10 (37.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herbette, LG; Mason, RP; Rhodes, DG1
Topliss, JG; Yoshida, F1
Jolivette, LJ; Nagilla, R; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brouillette, WJ; Brown, GB; Zha, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abete, P; Acanfora, D; Cicatiello, AM; Covelluzzi, F; De Caprio, L; Gallucci, F; Papa, M; Rengo, F1
Elliott, HL; McNally, C; Meredith, PA; Reid, JL1
Arrichiello, P; Bonaduce, D; Breglio, R; Lanzillo, T; Mazza, F; Morgano, G; Petretta, M1
Luo, SF; Yu, CL; Zhang, PW1
Leenen, FH; Levine, MA; Ogilvie, RI1
Duncker, DJ; Saxena, PR; Verdouw, PD2
Brooks, HL; Gross, GJ; Warltier, DC; Zyvoloski, MG1
Leenen, FH; Ogilvie, RI; Shaw-Stiffel, TA; Walker, SE1
Onodera, S; Sugawara, H; Tobise, K1
Battler, A; Blau, A; Eliahou, HE; Herz, I; Herzog, D; Schechter, P1
Kodama, Y; Matsunami, T; Miyahara, T; Saito, H; Sobue, T; Yokota, M1

Reviews

2 review(s) available for propranolol and nisoldipine

ArticleYear
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship

1991
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for propranolol and nisoldipine

ArticleYear
Acute effects of nisoldipine, propranolol, and their combination in patients with chronic stable angina: a double-blind, randomized, cross-over, placebo-controlled study.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Aged; Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Nisoldipine; Propranolol; Randomized Controlled Trials as Topic

1990
The interactions between nisoldipine and two beta-adrenoceptor antagonists--atenolol and propranolol.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:3

    Topics: Adult; Atenolol; Blood Pressure; Drug Interactions; Exercise; Heart Rate; Humans; Kidney; Liver; Male; Nisoldipine; Propranolol; Reference Values; Regional Blood Flow

1991
[Nisoldipine in the therapy of stable exercise angina: evaluation of its efficacy in ergometric tests compared with propranolol].
    Giornale italiano di cardiologia, 1990, Volume: 20, Issue:6

    Topics: Adult; Angina Pectoris; Coronary Circulation; Exercise; Exercise Test; Female; Humans; Male; Middle Aged; Myocardium; Nisoldipine; Oxygen Consumption; Propranolol

1990
Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:1

    Topics: Adult; Biological Availability; Calcium Channel Blockers; Double-Blind Method; Drug Interactions; Hemodynamics; Humans; Male; Nifedipine; Nisoldipine; Propranolol; Random Allocation; Receptors, Adrenergic, beta

1988
Pharmacokinetic and pharmacodynamic interactions during multiple-dose administration of nisoldipine and propranolol.
    Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:6

    Topics: Adult; Biological Availability; Drug Administration Schedule; Drug Interactions; Hemodynamics; Humans; Male; Nisoldipine; Propranolol; Reference Values

1994

Other Studies

20 other study(ies) available for propranolol and nisoldipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
[Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on beat rate and injury of cultured newborn rat myocardial cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:2

    Topics: Animals; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; L-Lactate Dehydrogenase; Myocardium; Nisoldipine; Phentolamine; Platelet Aggregation Inhibitors; Propranolol; Rats; Stilbenes

1990
Systemic haemodynamics of dihydropyridine derivatives in conscious pigs with or without propranolol.
    European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Nifedipine; Nimodipine; Nisoldipine; Propranolol; Swine; Vasodilation

1988
The effects of nisoldipine alone and in combination with beta-adrenoceptor blockade on systemic haemodynamics and myocardial performance in conscious pigs.
    European heart journal, 1987, Volume: 8, Issue:12

    Topics: Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Hemodynamics; Myocardial Contraction; Nifedipine; Nisoldipine; Propranolol; Regional Blood Flow; Swine; Vascular Resistance

1987
Comparative actions of dihydropyridine slow channel calcium blocking agents in conscious dogs: systemic and coronary hemodynamics with and without combined beta adrenergic blockade.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; Hydralazine; Male; Nifedipine; Nisoldipine; Nitrendipine; Propranolol; Vasodilator Agents

1984
Absence of antioxidant effects of nifedipine and diltiazem on myocardial membrane lipid peroxidation in contrast with those of nisoldipine and propranolol.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Animals; Antioxidants; Diltiazem; Fumarates; Heart; In Vitro Techniques; Lipid Peroxidation; Male; Myocardium; Nifedipine; Nisoldipine; Oxidation-Reduction; Oxygen; Propranolol; Rats; Rats, Sprague-Dawley

1994
Cardiovascular effects of nisoldipine in essential hypertension.
    Israel journal of medical sciences, 1994, Volume: 30, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nisoldipine; Propranolol; Radionuclide Ventriculography; Stroke Volume; Vascular Resistance

1994
Effect of antianginal agents on the relationship between rate-pressure product and myocardial oxygen uptake.
    American heart journal, 1993, Volume: 126, Issue:3 Pt 1

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Angiography; Drug Evaluation; Electrocardiography; Exercise Test; Female; Heart; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Nisoldipine; Oxygen Consumption; Propranolol; Regression Analysis

1993