Page last updated: 2024-08-16

propranolol and nimodipine

propranolol has been researched along with nimodipine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's5 (18.52)18.2507
2000's8 (29.63)29.6817
2010's11 (40.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herbette, LG; Mason, RP; Rhodes, DG1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Jolivette, LJ; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Agnoli, A; Aloise, V; Catarci, T; Cerbo, R; Chiarotti, F; D'Urso, R; Falaschi, P; Formisano, R; Proietti, A; Roberti, C1
Anzola, GP; Dalla Volta, G; DiMonda, V1
Cantó, T; Ceña, V; García, AG; González-García, C; Orellana, C; Orts, A1
Chester, DW; Herbette, LG; Katz, AM; Trumbore, M1
Duncker, DJ; Saxena, PR; Verdouw, PD1
Breuel, HP; Heine, PR; Kuhlmann, J; Mück, W; Niklaus, H; Schmage, N1
Marchand, L1
Sharma, HS; Winkler, T1
Zhang, X; Zhang, Z1
Chen, L; Huang, F; Li, W; Li, X; Liu, Z; Luo, Z; Wu, H; Xu, Y; Young, C; Zhou, S1

Reviews

2 review(s) available for propranolol and nimodipine

ArticleYear
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship

1991
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for propranolol and nimodipine

ArticleYear
Nimodipine in migraine: clinical efficacy and endocrinological effects.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:1

    Topics: Adult; Female; Growth Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Migraine Disorders; Nimodipine; Pituitary Hormones, Anterior; Prolactin; Propranolol

1991
Chronic administration of nimodipine and propranolol in elderly normotensive subjects--an interaction study.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:2

    Topics: Aged; Aged, 80 and over; Biological Availability; Blood Pressure; Cross-Over Studies; Drug Interactions; Electrocardiography; Female; Humans; Male; Middle Aged; Nimodipine; Propranolol; Pulse

1995

Other Studies

23 other study(ies) available for propranolol and nimodipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The disappearance of the "cold patch" in recovered migraine patients: thermographic findings.
    Headache, 1991, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Body Temperature; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Nimodipine; Prognosis; Propranolol; Thermography

1991
Inhibition of adrenomedullary catecholamine release by propranolol isomers and clonidine involving mechanisms unrelated to adrenoceptors.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Adrenal Medulla; Animals; Catecholamines; Cats; Cattle; Chromaffin System; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; Nimodipine; Perfusion; Potassium; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereoisomerism

1987
Possible molecular basis for the pharmacokinetics and pharmacodynamics of three membrane-active drugs: propranolol, nimodipine and amiodarone.
    Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:5

    Topics: Amiodarone; Animals; Kinetics; Lipid Bilayers; Membrane Lipids; Molecular Conformation; Neutrons; Nimodipine; Propranolol; Sarcolemma; Sarcoplasmic Reticulum; Spectrum Analysis; X-Ray Diffraction

1988
Systemic haemodynamics of dihydropyridine derivatives in conscious pigs with or without propranolol.
    European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Nifedipine; Nimodipine; Nisoldipine; Propranolol; Swine; Vasodilation

1988
[Treatment of essential tremor].
    L'union medicale du Canada, 1995, Volume: 124, Issue:3

    Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Botulinum Toxins; Humans; Hypnotics and Sedatives; Methazolamide; Nimodipine; Parkinson Disease; Phenobarbital; Primidone; Propranolol; Sympatholytics; Thalamus; Tremor; Vasodilator Agents

1995
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
    Muscle & nerve. Supplement, 2002, Volume: 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Coloring Agents; Cyproheptadine; Dexamethasone; Edema; Electrophysiology; Endothelium; Evans Blue; Evoked Potentials; Fenclonine; Ibuprofen; Indomethacin; Male; Nimodipine; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Spinal Cord Injuries

2002
[Two dimensional capillary zone electrophoresis/micellar electrokinetic capillary chromatography for the analysis of drugs and their enantiomers in urine samples].
    Se pu = Chinese journal of chromatography, 2010, Volume: 28, Issue:4

    Topics: Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Nimodipine; Polytetrafluoroethylene; Propranolol; Stereoisomerism

2010
The novel compound liguzinediol exerts positive inotropic effects in isolated rat heart via sarcoplasmic reticulum Ca2+ ATPase-dependent mechanism.
    Life sciences, 2012, Oct-05, Volume: 91, Issue:11-12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Male; Myocardial Contraction; Myocytes, Cardiac; Nimodipine; Ouabain; Prazosin; Propranolol; Pyrazines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin

2012