propranolol has been researched along with naloxone in 189 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (44.44) | 18.7374 |
| 1990's | 57 (30.16) | 18.2507 |
| 2000's | 23 (12.17) | 29.6817 |
| 2010's | 24 (12.70) | 24.3611 |
| 2020's | 1 (0.53) | 2.80 |
| Authors | Studies |
|---|---|
| Billings, JJ; Chumpradit, S; Kung, HF; Kung, MP | 1 |
| Billings, J; Chumpradit, S; Kung, HF; Kung, MP; Mach, R | 1 |
| Foulon, C; Kung, HF; Kung, MP | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Obach, RS; Orozco, CC; Strelevitz, TJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brazzolotto, X; Brus, B; Colletier, JP; Coquelle, N; Gobec, S; Jukič, M; Knez, D; Kos, J; Košak, U; Nachon, F; Pišlar, A; Podkowa, A; Sałat, K; Šink, R; Stojan, J; Trontelj, J; Žakelj, S; Živin, M | 1 |
| Menon, AM; Pleuvry, BJ | 1 |
| Cowan, A; Macfarlane, IR | 1 |
| Berkowitz, BA | 1 |
| Carrasco, MA; Dias, RD; Izquierdo, I; Souza, DO | 1 |
| Angelucci, L; Valeri, P | 1 |
| Ferri, S; Reina, R; Santagostino, A | 1 |
| Takemori, AE; Tulunay, FC; Yano, I | 1 |
| Winter, JC | 1 |
| Fu, TC; Guo, L; Liu, HJ; Peng, YI | 1 |
| Bidzseranova, A; Telegdy, G; Várga, J | 1 |
| Kaneto, H; Ohta, A | 1 |
| Caudle, RM; Chavkin, C; Simmons, ML; Wagner, JJ | 1 |
| Chin, J; Dart, A; Fullerton, M; Jennings, G; Shen, A | 1 |
| Bojö, L; Cassuto, J | 1 |
| Cho, WK; Kim, K; Lee, BJ; Lee, CC; Ramirez, VD | 1 |
| Koelbel, CB; Leduc, L; Mayer, EA; Snape, WJ; Vandeventer, G | 1 |
| Hiruma, H; Kimura, F; Nishihara, M | 1 |
| Foo, H; Westbrook, RF | 1 |
| Bidzseranova, A; Penke, B; Telegdy, G; Tóth, G | 1 |
| Borisova, EV; Kadar, T; Telegdi, G | 1 |
| Kihara, H; Nakagawa, T; Sogawa, H; Teshima, H | 1 |
| Barney, CC; Katovich, MJ; Pitman, DL | 1 |
| Camilleri, M; Malagelada, JR; Thomforde, GM; Yaksh, TL | 1 |
| Fich, A; Hanson, RB; Neri, M; Phillips, SF; Zinsmeister, AR | 1 |
| Miller, JF; Proudfit, HK | 1 |
| Hernandez, J; Laorden, ML; Romero, M; Serrano, JS | 1 |
| Datta, H; Saha, N; Sharma, PL | 1 |
| Caudle, RM; Chavkin, C; Wagner, JJ | 1 |
| Gianlupi, A; Netto, CA; Oliveira, CB; Quillfeldt, J | 1 |
| Ashmarin, IP; Chudakov, LI; Nikonova, IN; Sokolova, NA; Vinogradova, TM; Vlasov, GP; Volodin, ND | 1 |
| Kihara, H; Kubo, C; Mori, K; Nakagawa, T; Sogawa, H; Teshima, H | 1 |
| Gitter, S; Oron, Y; Sagy, M; Sarne, Y; Shavit, G; Vidne, BA | 1 |
| Couture, R; Laneuville, O; Reader, TA | 1 |
| Kampine, JP; Schmeling, WT; Warltier, DC | 1 |
| Hikasa, Y; Ogasawara, S; Takase, K | 1 |
| Demirtas, B; Goebell, H; Müller, MK; Rünzi, M; Schönfeld, JV; Soukup, J | 1 |
| Gu, YH; Wei, D | 2 |
| Gentil, B; Harf, A; Macquin-Mavier, I | 1 |
| Ellis, JL; Farmer, SG | 1 |
| Gregor, L; Thornhill, JA; Townsend, C | 1 |
| Hatch, RC; Jernigan, AD | 1 |
| Rand, MJ; Wong-Dusting, H | 1 |
| Introini-Collison, IB; McGaugh, JL; Nagahara, AH | 2 |
| Glick, SD; Hough, LB; Su, K | 1 |
| Puurunen, J | 1 |
| Dollery, CT; Struthers, AD | 1 |
| Jian, M | 1 |
| O'Neill, KA; Valentino, D | 1 |
| Bentley, GA; Starr, J | 1 |
| Joffe, S; Murphy, RF; Sperling, MA; Werther, GA | 1 |
| Knudtzon, J | 1 |
| Betti, R; Casanueva, FF; Cella, SG; Müller, EE | 1 |
| Russell, JA; Simons, EJ | 1 |
| Laurent, S; Marsh, JD; Smith, TW | 1 |
| Bethea, CL; Lorens, SA; Paris, J; Richardson, KD; Urban, JH; Van de Kar, LD | 1 |
| Izquierdo, I; McGaugh, JL | 1 |
| Hosomi, H; Koyama, S | 1 |
| Dean, HG; Furman, BL; Sidey, FM | 1 |
| Bragin, EO | 1 |
| Mu, J | 1 |
| Kameyama, T; Kozawa, T; Nabeshima, T | 1 |
| Delgoulet, C; Roquebert, J | 1 |
| Alvinerie, M; Bueno, L; Fioramonti, J; Frexinos, J; Gue, M | 1 |
| Lee, AY; Wong, TM | 2 |
| Graf, PD; Nadel, JA; Tamaoki, J | 1 |
| Gala, RR; Haisenleder, DJ | 1 |
| Ewen, M; Gregor, L; Saunders, WS; Thornhill, JA; Wilfong, AA | 1 |
| de Maria, G; Ortolani, E; Palazzesi, S | 1 |
| Bell, S; Jhamandas, K; Sutak, M | 1 |
| Askew, WE; Charalampous, KD | 1 |
| Bell, RD; Cicero, TJ; Meyer, ER | 1 |
| Peterson, GR; Shuster, L; Webster, GW | 1 |
| Kersh, ES; Schwartz, LK | 1 |
| Eades, CG; Flanary, HG; Martin, WR; Thompson, JA; Thompson, WO | 1 |
| Go, VL; Kao, PC; Malagelada, JR; Stanghellini, V; Zinsmeister, AR | 1 |
| Bryant, HU; Malven, PV; Yim, GK | 1 |
| Ristine, LA; Spear, LP | 1 |
| Evans, JM; Gillespie, MN; Knapp, CF; Rountree, RM | 1 |
| Gram, BR; Ottesen, B | 1 |
| Graudenz, M; Izquierdo, I | 1 |
| Akaike, A; Nakazawa, T; Satoh, M; Takagi, H | 1 |
| Schadt, JC; York, DH | 1 |
| Giles, TD; Sander, GE | 1 |
| Chan, HK; Chen, CF; Lin, MT; Teh, GW | 1 |
| Assan, R; Giraud, P; Helman, AM; Nicolaidis, S; Oliver, C | 1 |
| Imura, H; Kinoshita, F; Koh, T; Nakai, Y; Tsujii, S; Tsukada, T | 1 |
| Lee, TF; Myers, RD | 1 |
| Chen, CF; Chuang, KS; Lin, MT | 1 |
| Burnett, MA; Lang, DA; Matthews, DR; Turner, RC | 1 |
| Bennett, T; Gardiner, SM | 1 |
| Assan, R; Gilbert, M; Helman, A; Pfister-Lemaire, N; Réach, G | 1 |
| Aziz, LA; Forsling, ML | 1 |
| Farsang, C; Kunos, G; Ramirez-Gonzalez, MD; Tchakarov, L | 1 |
| Slater, P | 1 |
| Shannon, HE | 1 |
| Cohen, S; Ouyang, A | 1 |
| Itskovitz, J; LaGamma, EF; Rudolph, AM | 1 |
| Dowling, DA; Moore, RH | 2 |
| Cervo, L; Mennini, T; Poggesi, E; Rochat, C; Samanin, R | 1 |
| Collier, HO; Cuthbert, NJ; Francis, DL | 1 |
| Saavedra, JM | 1 |
| Boeck, V; Larsen, JJ; Ottesen, B | 1 |
| Carstens, E; Zimmermann, M | 1 |
| Chang, SS; Cheng, JT | 1 |
| Birnbaum, AK; Law, PY; Wilcox, GL; Wotta, DR | 1 |
| Levenson, J; Pandurangi, A; Silverman, J; Vieweg, V | 1 |
| Hasegawa, T; Maeda, Y; Nabeshima, T; Yamada, K | 1 |
| Goñalons, E; Jimenez, M; Martinez, V; Vergara, P | 1 |
| Aston-Jones, G; Harris, GC | 1 |
| Galiñanes, M; Hearse, DJ | 1 |
| Laorden, ML; Micol, JA | 1 |
| Chen, QS; Dai, YL; Xiao, Q; Yan, ZH; Yang, R | 1 |
| Bíró, E; Sarnyai, Z; Telegdy, G | 1 |
| Guo, XQ; Guo, Z; Liang, ZJ; Zhao, YM | 1 |
| Bicknell, RJ; Coombes, JE; Leng, G; Russell, JA | 1 |
| Harris, A; Martin, BJ | 1 |
| Bridges, MT; Grover, TE; Introna, RP; Pruett, JK; Yodlowski, EH | 1 |
| Farzin, D; Zarrindast, MR | 1 |
| Berkmiller, G; Falk, W; Frauenholz, T; Herrmann, M; Lang, B; Schölmerich, J; Straub, RH | 1 |
| Eikanger, J; Schlenker, EH | 1 |
| Biró, E; Penke, B; Telegdy, G | 1 |
| Azizi, N; Rezayat, M; Zarrindast, MR | 1 |
| Galbo, H; Hansen, MB; Kappel, M; Pedersen, BK; Poulsen, TD | 2 |
| Adeghate, E; Djali, PK; Singh, J | 1 |
| Bai, HQ; Li, FY; Li, Y; Wu, WR; Zhang, KR; Zheng, JW | 1 |
| Kovács, A; Penke, B; Telegdy, G; Tóth, G | 1 |
| Holsey, YS; Omoniyi, AT; Soong, Y; Szeto, HH; Wu, D | 1 |
| Aston-Jones, G; Delfs, JM; Druhan, J; Zhu, Y | 1 |
| Arndt, ML; Soong, Y; Szeto, HH; Wu, D | 1 |
| Bugajski, J; Cetera, B; Gadek-Michalska, A | 1 |
| Kannan, H; Kato, K; Kunitake, T; Shirasaka, T; Takasaki, M | 1 |
| Levine, JD; Miao, FJ | 1 |
| Chen, JY; Dafny, N; Kang, YM; Ouyang, W; Qiao, JT | 1 |
| Oliveira, MA; Prado, WA | 1 |
| Ge, L; Wang, H; Zou, CJ | 1 |
| Adamik, A; Telegdy, G | 4 |
| Douglas, AJ; Leng, G; Russell, JA | 1 |
| Benedetti, F; Pollo, A; Rainero, I; Vighetti, S | 1 |
| Maeda, A; Minami, M; Nakagawa, T; Satoh, M; Watanabe, T; Yamamoto, R | 1 |
| Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV | 1 |
| Cui, Y; Lai, LH; Wang, CL; Wang, R; Wang, X; Yu, Y | 1 |
| Parvizi, N; Phogat, JB | 2 |
| Naseri, MK; Yahyavi, H | 1 |
| Birgani, MO; Mohammadian, M; Naseri, MK; Naseri, ZG | 1 |
| Gewirtz, JC; Rothwell, PE; Thomas, MJ | 1 |
| Kunitake, T; Shirasaka, T; Tsuneyoshi, I | 1 |
| Hajhashemi, V; Minaiyan, M; Movahedian, A; Sadeghi, H; Talebi, A | 1 |
| Atapattu, RK; Kirby, LG; Schneider, AM; Simson, PE | 1 |
| Almela, P; Hurle, MA; Laorden, ML; Martínez-Laorden, E; Milanés, MV | 1 |
| Jose, R; Peedicayil, J; Shah, NH; Thomas, E | 1 |
| Daimon, CM; Keefe, J; Kirby, LG; Mrozewski, J; Schneider, AM; Simson, PE; Vogt, NM | 1 |
| Jászberényi, M; Telegdy, G | 1 |
| de Groat, WC; Rogers, MJ; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J; Xiao, Z | 1 |
| Bai, L; Chen, Q; Chen, Y; Du, XJ; Luo, P; Tian, XM; Tian, XZ | 1 |
| Bandari, J; Bansal, U; Chang, V; de Groat, WC; Lamm, V; Roppolo, JR; Shen, B; Tai, C; Wang, J; Zhang, Z | 1 |
| Beckel, J; Chermansky, C; de Groat, WC; Jian, J; Madhavaram, A; Pintauro, M; Scolieri, J; Shen, B; Tai, C; Wang, J | 1 |
7 review(s) available for propranolol and naloxone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Methadone; Morphine; Morphine Dependence; Naloxone; Propranolol; Protein Binding; Sex Factors; Substance-Related Disorders | 1976 |
Central nervous system mechanisms in blood pressure control.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Disease Models, Animal; Ganglia, Sympathetic; Half-Life; Hypothalamus; Models, Neurological; Naloxone; Neurons; Nitroprusside; Norepinephrine; Phenylethanolamine N-Methyltransferase; Pressoreceptors; Propranolol; Rats; Rats, Inbred SHR; Receptors, Opioid; Reflex; Splanchnic Nerves; Thiophenes; Yohimbine | 1985 |
Renal opiate receptor mediation of renin secretion to renal nerve stimulation in the dog.
Topics: Animals; Dogs; Electric Stimulation; Enkephalin, Leucine; Female; Kidney; Male; Naloxone; Nervous System Physiological Phenomena; Phentolamine; Propranolol; Receptors, Opioid; Renin | 1986 |
Opioid and catecholaminergic mechanisms of different types of analgesia.
Topics: Acetates; Acetic Acid; Acupuncture Therapy; Analgesia; Animals; Electric Stimulation; Electroshock; Endorphins; Formaldehyde; Haloperidol; Hot Temperature; Hydroxydopamines; Naloxone; Oxidopamine; Pain; Potassium Chloride; Propranolol; Rats; Reserpine; Sensory Thresholds | 1986 |
The consulting psychiatrist and the polydipsia-hyponatremia syndrome in schizophrenia.
Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Carbamazepine; Cognition Disorders; Demeclocycline; Drinking Behavior; Electroconvulsive Therapy; Humans; Hyponatremia; Lithium; Mood Disorders; Naloxone; Phenytoin; Polyuria; Propranolol; Psychiatry; Psychotherapy; Schizophrenia; Sodium Chloride; Syndrome; Water Intoxication; Workforce | 1994 |
5 trial(s) available for propranolol and naloxone
| Article | Year |
|---|---|
Effect of opiate and adrenergic blockers on the gut motor response to centrally acting stimuli.
Topics: Adult; Aged; beta-Endorphin; Blood Pressure; Catecholamines; Dose-Response Relationship, Drug; Endorphins; Female; Gastrointestinal Motility; Humans; Male; Middle Aged; Naloxone; Norepinephrine; Phentolamine; Propranolol; Pyloric Antrum; Stress, Physiological; Sympathetic Nervous System | 1984 |
Somatostatin attenuates the hyperthermia induced increase in neutrophil concentration.
Topics: Adult; Cross-Over Studies; Fever; Hot Temperature; Humans; Immersion; Killer Cells, Natural; Kinetics; Leukocyte Count; Lymphocyte Count; Male; Naloxone; Neutrophils; Propranolol; Somatostatin | 1998 |
Immune changes during whole body hot water immersion: the role of growth hormone.
Topics: Adrenergic beta-Antagonists; Adult; Body Temperature; Endorphins; Fever; Growth Hormone; Hormone Antagonists; Hot Temperature; Humans; Immersion; Killer Cells, Natural; Leukocytes; Leukocytes, Mononuclear; Leukocytosis; Male; Naloxone; Narcotic Antagonists; Neutrophils; Propranolol; Sodium Chloride; Somatostatin; Water | 1997 |
Placebo analgesia and the heart.
Topics: Adult; Analgesia; Anti-Arrhythmia Agents; Atropine; Double-Blind Method; Electric Stimulation; Electroencephalography; Female; Heart; Heart Rate; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Placebo Effect; Propranolol | 2003 |
Involvement of opioids and catecholamines in stress modulation of LH secretion in the male pig.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Catecholamines; Luteinizing Hormone; Male; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Orchiectomy; Propranolol; Stress, Psychological; Swine; Swine, Miniature | 2010 |
177 other study(ies) available for propranolol and naloxone
| Article | Year |
|---|---|
Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor.
Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution | 1991 |
Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
Topics: Animals; Benzamides; Dopamine Agents; Dopamine D2 Receptor Antagonists; Fluorine Radioisotopes; Iodine Radioisotopes; Macaca fascicularis; Male; Pyrrolidines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1993 |
Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'- propenyl)-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand.
Topics: Binding Sites; Dopamine Agents; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Salicylamides; Stereoisomerism; Tetrahydronaphthalenes | 1993 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
Topics: Acetamides; Aldehyde Oxidase; Cryopreservation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Activation; Hepatocytes; Humans; Hydralazine; Liver; Microsomes, Liver; Pyrimidines | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.
Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Female; Humans; Kinetics; Male; Mice; Models, Molecular; Protein Binding; Protein Conformation; Rats; Safety; Thermodynamics; Tissue Distribution | 2018 |
A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse.
Topics: Adrenalectomy; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Hypothermia; Male; Meperidine; Mice; Morphine; Naloxone; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Reserpine; Species Specificity | 1976 |
Effect of propranolol on antinociceptive, tolerance- and dependence-producing properties of morphine in rodents and monkeys.
Topics: Analgesics, Opioid; Animals; Drug Interactions; Drug Tolerance; Female; Haplorhini; Humans; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Practolol; Propranolol; Rats; Reaction Time; Stereoisomerism; Substance Withdrawal Syndrome; Time Factors | 1975 |
Effect of naloxone, haloperidol and propranolol on cyclic 3',5'-adenosine monophosphate content of rat amygdala.
Topics: Amygdala; Animals; Caudate Nucleus; Cyclic AMP; Drug Interactions; Female; Haloperidol; Hippocampus; Hypothalamus; In Vitro Techniques; Naloxone; Nerve Tissue Proteins; Propranolol; Rats | 1979 |
Influence of social environment and of drugs on 3H-corticosterone uptake in various brain areas.
Topics: Animals; Brain; Chlorpromazine; Corticosterone; Female; Humans; Limbic System; Male; Metergoline; Mice; Morphine; Naloxone; Propranolol; Rats; Receptors, Glucocorticoid; Receptors, Steroid; Social Environment; Stress, Psychological; Tritium | 1978 |
Dopamine and the depressant action of morphine on stimulated guinea-pig ileum.
Topics: Animals; Apomorphine; Dopamine; Electric Stimulation; Female; Guinea Pigs; Hydroxydopamines; Ileum; Male; Morphine; Muscle Contraction; Naloxone; Phentolamine; Propranolol | 1977 |
Differential effects on morphine analgesia and naloxone antagonism by biogenic amine modifiers.
Topics: Animals; Atropine; Biogenic Amines; Brain; Dopamine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Physostigmine; Propranolol; Receptors, Drug; Serotonin | 1975 |
The stimulus properties of morphine and ethanol.
Topics: Animals; Conditioning, Operant; Dextrorphan; Discrimination, Psychological; Ethanol; Female; Levorphanol; Morphine; Naloxone; Pharmaceutical Preparations; Propranolol; Rats; Sodium Chloride; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship | 1975 |
Mechanisms of adrenaline-induced antinociception in mice.
Topics: Analgesics; Animals; Epinephrine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Pain; Prazosin; Propranolol; Sensory Thresholds; Yohimbine | 1992 |
The effects of receptor blockers on brain natriuretic peptide-32-induced action on passive avoidance behavior in rats.
Topics: Animals; Atropine; Avoidance Learning; Brain; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Naloxone; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Propranolol; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter | 1992 |
Development of physical dependence on morphine not accompanied with tolerance formation.
Topics: Analgesia; Animals; Drug Interactions; Drug Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Naloxone; Phentolamine; Propranolol | 1992 |
Endogenous opioid regulation of norepinephrine release in guinea pig hippocampus.
Topics: Animals; Calcium; Electric Stimulation; Endorphins; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Naloxone; Norepinephrine; Propranolol; Radioligand Assay | 1992 |
Increases in plasma beta-endorphin concentrations during exercise do not contribute to increases in heart rate following autonomic blockade in man.
Topics: Adolescent; Adult; Atropine; beta-Endorphin; Exercise; Heart Rate; Humans; Male; Naloxone; Propranolol | 1992 |
Gastric reflex relaxation by colonic distension.
Topics: Anesthesia; Animals; Colon; Gastrointestinal Motility; Muscle Tonus; Naloxone; Potassium Chloride; Prazosin; Pressure; Propranolol; Rats; Rats, Inbred Strains; Reflex; Vagotomy; Yohimbine | 1992 |
Adrenergic mediation of the naloxone-induced GnRH release from hypothalami of ovariectomized, steroid-treated immature rats.
Topics: Adrenergic Fibers; Animals; Ditiocarb; Estrogens; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Injections; Naloxone; Ovariectomy; Phenoxybenzamine; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1991 |
Neurokinin inhibition of cholinergic myenteric neurons in canine antrum.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurokinin A; Neurons; Nifedipine; Phentolamine; Propranolol; Pyloric Antrum; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Interactions between the noradrenergic and opioid peptidergic systems in controlling the electrical activity of luteinizing hormone-releasing hormone pulse generator in ovariectomized rats.
Topics: Animals; Electrodes, Implanted; Endorphins; Female; Gonadotropin-Releasing Hormone; Naloxone; Norepinephrine; Ovariectomy; Ovary; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Secretory Rate | 1991 |
Naloxone-induced hypoalgesia: effects of noradrenergic antagonists and agonist.
Topics: Animals; Clonidine; Hot Temperature; Male; Naloxone; Norepinephrine; Pain; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds; Yohimbine | 1991 |
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Topics: Amnesia; Animals; Atrial Natriuretic Factor; Atropine; Avoidance Learning; Bicuculline; Electroshock; Haloperidol; Male; Memory; Methysergide; Naloxone; Phenoxybenzamine; Propranolol; Rats | 1991 |
Neuropeptide Y and catecholamine-mediated neuronal transmission in mechanisms of feeding-behaviour induction.
Topics: Animals; Feeding Behavior; Naloxone; Neuropeptide Y; Prazosin; Propranolol; Rats; Rats, Wistar; Yohimbine | 1991 |
Influence of stress on the maturity of T-cells.
Topics: Animals; Antigens, Ly; Atropine; Diazepam; Female; Immobilization; Leukocyte Count; Mice; Mice, Inbred C3H; Naloxone; Propranolol; Spleen; Stress, Physiological; T-Lymphocyte Subsets; Thymus Gland | 1991 |
Mechanisms mediating the thermal response to morphine withdrawal in rats.
Topics: Adrenal Glands; Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Female; Morphine; Naloxone; Propranolol; Rats; Receptors, Adrenergic; Skin Temperature; Substance Withdrawal Syndrome | 1990 |
Demonstration of intrathecal and systemic morphine and ST-91 effects on fed canine upper gut motility.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Drug Interactions; Eating; Gastrointestinal Motility; Injections, Intravenous; Injections, Spinal; Morphine; Naloxone; Phentolamine; Propranolol | 1990 |
Regulation of postprandial motility in the canine ileum.
Topics: Animals; Atropine; Dogs; Eating; Fasting; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Ileum; Manometry; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Prostaglandins H; Verapamil | 1990 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Female; Injections, Spinal; Methysergide; Microinjections; Naloxone; Neurons; Pain; Phentolamine; Pons; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1990 |
Evidence for involvement of catecholamines in the effect of morphine on ventricular automaticity in the rat.
Topics: Animals; Drug Interactions; Female; Heart; In Vitro Techniques; Male; Morphine; Naloxone; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Ventricular Function, Right | 1991 |
Effects of morphine on memory: interactions with naloxone, propranolol and haloperidol.
Topics: Animals; Dopamine; Haloperidol; Male; Memory; Mice; Mice, Inbred ICR; Morphine; Naloxone; Propranolol; Sympathetic Nervous System | 1991 |
Endogenous opioids released from perforant path modulate norepinephrine actions and inhibitory postsynaptic potentials in guinea pig CA3 pyramidal cells.
Topics: Animals; Electric Stimulation; Electrophysiology; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Hippocampus; Male; Membrane Potentials; Naloxone; Norepinephrine; Propranolol; Pyramidal Tracts; Synapses | 1991 |
Effect of atropine and propranolol on retrieval enhancement by a novel experience or by injection of beta-endorphin prior to testing in rats.
Topics: Analysis of Variance; Animals; Atropine; Avoidance Learning; beta-Endorphin; Female; Memory; Naloxone; Photic Stimulation; Propranolol; Rats; Rats, Inbred Strains; Retention, Psychology | 1990 |
[The positive chronotropic effects of salsolinol on the isolated rat heart].
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Heart Rate; In Vitro Techniques; Isoquinolines; Male; Naloxone; Perfusion; Propranolol; Rats; Stimulation, Chemical | 1990 |
Prevention of immunosuppression in stressed mice by neurotropin(NSP).
Topics: Animals; Atropine; Body Weight; Cytotoxicity, Immunologic; Diazepam; Female; Immune Tolerance; Killer Cells, Natural; Lymphoma; Macrophages; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Naloxone; Organ Size; Phagocytosis; Polysaccharides; Propranolol; Reference Values; Restraint, Physical; Stress, Psychological; T-Lymphocyte Subsets | 1990 |
Nonopiate effect of naloxone on cardiac muscle contractility.
Topics: Animals; Heart; Heart Atria; Humans; In Vitro Techniques; Injections; Morphine; Myocardial Contraction; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stroke Volume | 1987 |
Intrathecal bradykinin acts presynaptically on spinal noradrenergic terminals to produce antinociception in the rat.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Biogenic Monoamines; Bradykinin; Catecholamines; Catheters, Indwelling; Dioxanes; Endorphins; Hydroxydopamines; Idazoxan; Injections, Spinal; Kallidin; Male; Naloxone; Oxidopamine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Yohimbine | 1989 |
Negative chronotropic actions of sufentanil and vecuronium in chronically instrumented dogs pretreated with propranolol and/or diltiazem.
Topics: Analgesics; Animals; Diltiazem; Dogs; Drug Interactions; Electrocardiography; Fentanyl; Heart Rate; Hemodynamics; Naloxone; Propranolol; Sufentanil; Vecuronium Bromide | 1989 |
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Chlorpromazine; Diphenhydramine; Domperidone; Female; Hydroxydopamines; Male; Naloxone; Oxidopamine; Propranolol; Random Allocation; Receptors, Adrenergic, alpha; Thiazines; Vomiting; Xylazine | 1989 |
Effect of neural blockade on somatostatin-induced inhibition of exocrine pancreatic secretion.
Topics: Animals; Atropine; Male; Naloxone; Pancreas; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sincalide; Somatostatin; Vagotomy | 1989 |
[Mechanisms underlying depressor and bradycardia effects of A1-excitation in rats].
Topics: Animals; Bicuculline; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1989 |
[Mechanisms underlying depressor and bradycardia effects of A5-excitation (compared with that of A1-excitation) in rats].
Topics: Animals; Bicuculline; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1989 |
Fentanyl-induced airway hyperreactivity in the guinea pig.
Topics: Animals; Atropine; Bronchial Provocation Tests; Drug Interactions; Fentanyl; Guinea Pigs; Histamine; Male; Muscle Tonus; Naloxone; Propranolol; Respiration; Serotonin | 1989 |
The effects of vasoactive intestinal peptide (VIP) antagonists, and VIP and peptide histidine isoleucine antisera on non-adrenergic, non-cholinergic relaxations of tracheal smooth muscle.
Topics: Adenosine; Animals; Antibodies; Atropine; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Naloxone; Peptide PHI; Propranolol; Sympathectomy, Chemical; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide | 1989 |
Intravenous morphine infusion (IMF) to drug-naive, conscious rats evokes bradycardic, hypotensive effects, but pressor actions are elicited after IMF to rats previously given morphine.
Topics: Animals; Atropine; Blood Pressure; Guanethidine; Heart Rate; Infusions, Intravenous; Male; Morphine; Naloxone; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice.
Topics: 4-Aminopyridine; Alcoholic Intoxication; Aminophylline; Aminopyridines; Amphetamine; Animals; Azides; Benzodiazepines; Dextroamphetamine; Doxapram; Ethanol; Male; Mice; Naloxone; Physostigmine; Propranolol; Sleep; Thyrotropin-Releasing Hormone; Yohimbine | 1988 |
Effects of the opioid peptides [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8 on cholinergic neurotransmission in the rabbit isolated atria.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heart; Heart Rate; In Vitro Techniques; Male; Naloxone; Parasympathetic Nervous System; Propranolol; Rabbits; Synaptic Transmission | 1987 |
Memory-enhancing effects of posttraining naloxone: involvement of beta-noradrenergic influences in the amygdaloid complex.
Topics: Amygdala; Animals; Avoidance Learning; Caudate Nucleus; Cerebral Cortex; Discrimination, Psychological; Learning; Male; Memory; Naloxone; Propranolol; Putamen; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1988 |
A role for histamine and histamine H2-receptors in non-opiate footshock-induced analgesia.
Topics: Animals; Cimetidine; Electroshock; Haloperidol; Histamine; Histamine H2 Antagonists; Male; Naloxone; Pain; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H2 | 1985 |
Role of putative neurotransmitters in the central gastric antisecretory effect of prostaglandin E2 in rats.
Topics: 5,6-Dihydroxytryptamine; Adrenergic alpha-Antagonists; Animals; Dinoprostone; Dioxanes; Female; Fenclonine; Gastric Juice; Histamine Antagonists; Hydroxydopamines; Idazoxan; Injections, Intraventricular; Male; Naloxone; Neurotransmitter Agents; Oxidopamine; Phentolamine; Propranolol; Prostaglandins E; Rats; Rats, Inbred Strains; Sulpiride; Theophylline | 1985 |
Influence of adrenergic antagonist and naloxone on the anti-allergic shock effect of electro-acupuncture in mice.
Topics: Acupuncture Therapy; Anaphylaxis; Animals; Electric Stimulation; Female; Male; Mice; Mice, Inbred Strains; Naloxone; Phentolamine; Practolol; Propranolol | 1985 |
Chronic desipramine attenuates morphine analgesia.
Topics: Analgesics, Opioid; Animals; Desipramine; Drug Interactions; Male; Mice; Morphine; Naloxone; Naltrexone; Propranolol; Reaction Time | 1986 |
The antinociceptive action of some beta-adrenoceptor agonists in mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analgesics; Animals; Dopamine; Drug Interactions; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Narcotics; Piperoxan; Propranolol | 1986 |
The regulation of basal pancreatic polypeptide levels in dogs.
Topics: Animals; Dogs; Enkephalin, Methionine; Female; Glucagon; Insulin; Naloxone; Pancreatic Polypeptide; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid; Somatostatin | 1987 |
Memory enhancement with intra-amygdala post-training naloxone is blocked by concurrent administration of propranolol.
Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Male; Memory; Naloxone; Propranolol; Rats; Rats, Inbred Strains; Retention, Psychology | 1989 |
Hypoinsulinemic and hyperglycemic effects of beta-endorphin in rabbits.
Topics: Animals; Atropine; beta-Endorphin; Blood Glucose; Endorphins; Female; Glucagon; Hyperglycemia; Injections, Intravenous; Insulin; Naloxone; Phentolamine; Propranolol; Quaternary Ammonium Compounds; Rabbits; Yohimbine | 1986 |
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission | 1985 |
Modulation of cholinergic neurotransmission in airways by enkephalin.
Topics: Acetylcholine; Animals; Depression, Chemical; Dogs; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Muscle Contraction; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Propranolol; Receptors, Opioid; Synaptic Transmission; Trachea | 1985 |
Enkephalins have a direct positive inotropic effect on cultured cardiac myocytes.
Topics: Animals; Brain; Calcium; Chick Embryo; Enkephalins; Isoproterenol; Myocardial Contraction; Myocardium; Naloxone; Propranolol; Receptors, Opioid | 1985 |
Pharmacological studies on stress-induced renin and prolactin secretion: effects of benzodiazepines, naloxone, propranolol and diisopropyl fluorophosphate.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Isoflurophate; Juxtaglomerular Apparatus; Male; Midazolam; Naloxone; Pituitary Gland, Anterior; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Renin; Stress, Psychological | 1985 |
Delayed onset of the amnestic effect of posttraining beta-endorphin: effects of propranolol administered prior to retention testing.
Topics: Amnesia; Animals; beta-Endorphin; Endorphins; Male; Memory; Mice; Naloxone; Propranolol; Receptors, Adrenergic, beta; Retention, Psychology; Time Factors | 1985 |
Role of the adrenal medulla in stress-induced hyperinsulinaemia in normal mice and in mice infected with Bordetella pertussis or treated with pertussis toxin.
Topics: Adrenal Medulla; Animals; Dioxanes; Ether; Female; Hexamethonium Compounds; Idazoxan; Insulin; Mice; Naloxone; Pertussis Toxin; Propranolol; Rats; Rats, Inbred Strains; Stress, Physiological; Virulence Factors, Bordetella; Whooping Cough | 1988 |
The study of the acupuncture effect on experimental allergic shock in mice.
Topics: Acupuncture Therapy; Anaphylaxis; Animals; Electric Stimulation Therapy; Female; Male; Mice; Mice, Inbred ICR; Naloxone; Phentolamine; Propranolol | 1986 |
Conditioned suppression of motility: possibility for evaluation of learning and memory in mice.
Topics: Animals; Conditioning, Psychological; Cycloheximide; Cyproheptadine; Electroshock; Male; Memory; Mice; Motor Activity; Naloxone; Phencyclidine; Physostigmine; Propranolol; Scopolamine | 1988 |
Cardiovascular effects of etorphine in rats.
Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Etorphine; Heart Rate; Hemodynamics; Male; Morphinans; Naloxone; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Vagotomy | 1988 |
Influence of acoustic stress by noise on gastrointestinal motility in dogs.
Topics: Animals; Corticotropin-Releasing Hormone; Diazepam; Dogs; Gastrointestinal Motility; Hydrocortisone; Muscimol; Naloxone; Noise; Phentolamine; Propranolol; Stomach; Stress, Physiological; Vagus Nerve | 1987 |
Antiarrhythmic potency of naloxone determined by a screening test using the isolated ischaemic perfused rat heart preparation.
Topics: Animals; Anti-Arrhythmia Agents; Female; Lidocaine; Naloxone; Propranolol; Quinidine; Rats; Rats, Inbred Strains; Ventricular Fibrillation | 1987 |
Effect of gamma-aminobutyric acid on neurally mediated contraction of guinea pig trachealis smooth muscle.
Topics: Acetylcholine; Animals; Baclofen; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Hemicholinium 3; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Trachea | 1987 |
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone.
Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics | 1986 |
Pressor effects of systemic administration of methionine and leucine enkephalin in the conscious rat.
Topics: Animals; Atropine; Blood Pressure; Diprenorphine; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Guanethidine; Heart Rate; Naloxone; Norepinephrine; Phentolamine; Propranolol; Rats | 1986 |
Naloxone and propranolol inhibit the disruption of the hippocampal theta waves induced by D-lysergic acid diethylamide in the rabbit.
Topics: Animals; Electroencephalography; Hippocampus; Lysergic Acid Diethylamide; Male; Naloxone; Propranolol; Rabbits; Theta Rhythm | 1986 |
Naloxone reduces release of creatine kinase in the isolated ischemic rat heart.
Topics: Animals; Coronary Disease; Creatine Kinase; Female; In Vitro Techniques; Myocardium; Naloxone; Propranolol; Rats; Rats, Inbred Strains | 1985 |
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline | 1973 |
Effect of non-opiate antagonists on stereospecific opiate receptor binding of tritiated naloxone.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Binding, Competitive; Brain; Bucladesine; Filtration; Fluorides; Isoproterenol; Levorphanol; Male; Mice; Naloxone; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Drug; Structure-Activity Relationship; Theophylline; Tritium | 1974 |
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Chemical; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Pentobarbital; Phenoxybenzamine; Phentolamine; Promethazine; Propranolol; Rats; Substance Withdrawal Syndrome; Time Factors | 1974 |
Effect of narcotics on enzymes of acetylcholine metabolism in cultured cells from embryonic chick brains.
Topics: Acetylcholine; Acetylcholinesterase; Acetyltransferases; Amino Acids; Animals; Brain; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Choline; Drug Tolerance; Leucine; Levorphanol; Morphine; Naloxone; Narcotics; Nerve Tissue Proteins; Neurons; Parasympathetic Nervous System; Propranolol; Stereoisomerism; Sympathetic Nervous System; Time Factors; Tritium | 1974 |
Narcotic poisoning: an epidemic disease.
Topics: Diazepam; Glucose; Hospitalization; Humans; Hyperglycemia; Methadone; Myelitis, Transverse; Myoglobinuria; Naloxone; Narcotics; New York City; Pneumonia, Aspiration; Propranolol; Pulmonary Edema; Respiration; Substance Withdrawal Syndrome; Substance-Related Disorders; Tetanus Toxoid | 1973 |
Morphine physical dependence in the dog.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dogs; Dose-Response Relationship, Drug; Haloperidol; Hot Temperature; Humans; Morphinans; Morphine; Morphine Dependence; Naloxone; Propranolol; Pulse; Pupil; Reflex; Respiration; Skin; Substance Withdrawal Syndrome; Time Factors | 1974 |
Differential inhibition by propranolol of feeding induced in rats by various stimuli.
Topics: Animals; Cyclazocine; Deoxyglucose; Dose-Response Relationship, Drug; Eating; Ethylketocyclazocine; Insulin; Male; Naloxone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Suckling behavior in neonatal rats: psychopharmacological investigations.
Topics: Animals; Animals, Newborn; Haloperidol; Metergoline; Methiothepin; Methysergide; Naloxone; Neurotransmitter Agents; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Scopolamine; Sucking Behavior | 1982 |
Attenuation of vagal noradrenergic tachycardia by naloxone.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Atropine; Dogs; Electric Stimulation; Female; Heart Rate; Male; Naloxone; Norepinephrine; Propranolol; Vagus Nerve | 1984 |
Increased myometrial blood flow evoked by substance P.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Female; Myometrium; Naloxone; Phenoxybenzamine; Propranolol; Rabbits; Regional Blood Flow; Substance P; Uterus | 1982 |
Memory facilitation by naloxone is due to release of dopaminergic and beta-adrenergic systems from tonic inhibition.
Topics: Animals; Dextroamphetamine; Dopamine; Drug Interactions; Female; Haloperidol; Memory; Naloxone; Neural Inhibition; Nicotine; Phenoxybenzamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tolazoline | 1980 |
Evidence for involvement of separate mechanisms in the production of analgesia by electrical stimulation of the nucleus reticularis paragigantocellularis and nucleus raphe magnus in the rat.
Topics: Animals; Brain Stem; Electric Stimulation; Male; Methysergide; Naloxone; Nociceptors; Norepinephrine; Phenoxybenzamine; Propranolol; Raphe Nuclei; Rats; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Reticular Formation; Synaptic Transmission | 1980 |
Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit.
Topics: Adrenergic Fibers; Animals; Atropine; Blood Pressure; Efferent Pathways; Heart Rate; Hemodynamics; Hemorrhage; Hypotension; Male; Naloxone; Naltrexone; Parasympathetic Nervous System; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Opioid | 1982 |
Interactions of leucine-enkephalin with alpha-adrenoceptors in the conscious dog.
Topics: Animals; Blood Pressure; Chemoreceptor Cells; Clonidine; Consciousness; Dogs; Enkephalin, Leucine; Heart Rate; Naloxone; Prazosin; Pressoreceptors; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1983 |
Involvement of both opiate and catecholaminergic receptors in the behavioural excitation provoked by thyrotropin-releasing hormone: comparisons with amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Haloperidol; Humans; Hyperkinesis; Male; Naloxone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Thyrotropin-Releasing Hormone; Yohimbine | 1983 |
Glucagon release after stimulation of the lateral hypothalamic area in rats: predominant beta-adrenergic transmission and involvement of endorphin pathways.
Topics: Animals; Atropine; beta-Endorphin; Blood Glucose; Catecholamines; Endorphins; Glucagon; Hypothalamic Area, Lateral; Male; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Evidence for noradrenergic involvement in naloxone-induced stimulation of luteinizing hormone release in prepubertal female rats.
Topics: Animals; Ditiocarb; Drug Interactions; Female; Luteinizing Hormone; Naloxone; Norepinephrine; Phenoxybenzamine; Propranolol; Radioimmunoassay; Rats; Rats, Inbred Strains | 1983 |
Calmodulin-induced feeding in the satiated cat: evidence for involvement of calcium and norepinephrine in the brain.
Topics: Animals; Body Temperature; Brain; Calcium; Calmodulin; Calmodulin-Binding Proteins; Cats; Egtazic Acid; Feeding Behavior; Female; Injections, Intraventricular; Magnesium; Naloxone; Norepinephrine; Phentolamine; Phosphoprotein Phosphatases; Propranolol; Satiation | 1984 |
Both dopaminergic and adrenergic receptors in the brain are involved in the behavioural excitation induced by dibutyryl 3',5'-adenosine monophosphate and aminophylline in the rat.
Topics: Aminophylline; Animals; Behavior, Animal; Brain; Bucladesine; Haloperidol; Injections, Intraventricular; Male; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Yohimbine | 1984 |
Control of pulsatile insulin secretion in man.
Topics: Adult; Aged; Atropine; Blood Glucose; Diabetes Mellitus; Female; Glucose; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Naloxone; Phentolamine; Propranolol; Sodium Salicylate; Tolbutamide; Vagotomy | 1983 |
Post-adrenalectomy hypotension in rats; absence of baroreflex resetting or effect of naloxone.
Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Nitroglycerin; Potassium; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sodium | 1983 |
Glucagon and insulin secretion and their biological activities in hypothermic rats.
Topics: Animals; Arginine; Atropine; Blood Glucose; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Catecholamines; Glucagon; Haloperidol; Hydrogen-Ion Concentration; Hypothermia, Induced; Insulin; Insulin Secretion; Liver Circulation; Male; Naloxone; Oxygen; Partial Pressure; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1984 |
Release of vasopressin in response to hypoxia and the effect of aminergic and opioid antagonists.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Guanethidine; Heart Rate; Hypoxia; Levallorphan; Male; Metoclopramide; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sympatholytics | 1983 |
Possible role of an endogenous opioid in the antihypertensive action of propranolol in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Endorphins; Heart Rate; Hypertension; Male; Naloxone; Propranolol; Rats; Rats, Inbred Strains | 1983 |
Pharmacological profile of wet-dog shaking induced by electrical stimulation of the fornix in rats.
Topics: Adenosine; Aminooxyacetic Acid; Animals; Atropine; Behavior, Animal; Dopamine; Electric Stimulation; Electrodes, Implanted; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Limbic System; Naloxone; Naltrexone; Neural Pathways; Physostigmine; Picrotoxin; Propranolol; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Pharmacological evaluation of N-allynormetazocine (SKF 10,047) on the basis of its discriminative stimulus properties in the rat.
Topics: Animals; Benzomorphans; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Phenazocine; Phencyclidine; Propranolol; Rats; Rats, Inbred F344; Stereoisomerism | 1983 |
Multiple 5-hydroxytryptamine receptors on feline ileum and ileocecal sphincter.
Topics: Adrenalectomy; Animals; Cats; Cinanserin; Electric Conductivity; Ileocecal Valve; Ileum; Methysergide; Muscle Contraction; Naloxone; Propranolol; Receptors, Serotonin; Serotonin; Tetrodotoxin | 1983 |
Effects of naloxone on fetal circulatory responses to hypoxemia.
Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Cardiovascular System; Endorphins; Female; Fetus; Heart Rate; Hypoxia; Naloxone; Pregnancy; Propranolol; Sheep | 1982 |
Effects of enkephalins on perfusion pressure in isolated hindlimb preparations.
Topics: Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Antagonism; Enkephalin, Leucine; Enkephalin, Methionine; Female; Femoral Artery; In Vitro Techniques; Injections, Intra-Arterial; Male; Naloxone; Perfusion; Propranolol; Vasodilation | 1982 |
Reduction in the number of serotonin receptors in the brainstem of morphine dependent rats: relation to blockade of naloxone precipitated jumping by serotonin agonists.
Topics: Animals; Behavior, Animal; Brain Stem; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Piperazines; Propranolol; Quipazine; Rats; Receptors, Serotonin; Serotonin; Substance Withdrawal Syndrome | 1980 |
Clonidine dependence in the guinea-pig isolated ileum.
Topics: Animals; Clonidine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Substance-Related Disorders | 1981 |
Effects of intravenously administered Leu- or Met-enkephalin on arterial blood pressure.
Topics: Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intravenous; Male; Naloxone; Propranolol | 1980 |
Spontaneously (genetic) hypertensive rats: naloxone-reversible and propranolol-reversible decrease in pain sensitivity.
Topics: Animals; Hypertension; Male; Naloxone; Pain; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds | 1981 |
Effect of vasoactive intestinal polypeptide on cerebral blood flow in the goat.
Topics: Animals; Atropine; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Goats; Naloxone; Phentolamine; Propranolol; Vasoactive Intestinal Peptide | 1981 |
The opiate antagonist naloxone does not consistently block inhibition of spinal nociceptive transmission produced by stimulation in lateral midbrain reticular formation of the cat.
Topics: Afferent Pathways; Animals; Cats; Endorphins; Mesencephalon; Naloxone; Pain; Phentolamine; Propranolol; Reticular Formation; Spinal Cord | 1980 |
Inhibitory effect of octopamine on the release of endogenous acetylcholine from isolated myenteric synaptosomes of guinea-pig.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium; Dopamine Agents; Female; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Myenteric Plexus; Naloxone; Nomifensine; Octopamine; Propranolol; Substance P; Synaptosomes | 1993 |
Functional expression of adrenergic and opioid receptors in Xenopus oocytes: interaction between alpha 2- and beta 2-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; Brimonidine Tartrate; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Dose-Response Relationship, Drug; Isoproterenol; Models, Biological; Naloxone; Oocytes; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Receptors, Opioid; RNA, Messenger; Xenopus laevis | 1995 |
Neuronal mechanism of the inhibitory effect of calcitonin on N-methyl-D-aspartate-induced aversive behavior.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Calcitonin; Cystamine; GABA Antagonists; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Phentolamine; Pindolol; Piperazines; Propranolol; Receptors, Neurotransmitter; Ritanserin; Serotonin Antagonists; Tropanes | 1995 |
Mechanism of action of CCK in avian gastroduodenal motility: evidence for nitric oxide involvement.
Topics: Animals; Arginine; Atropine; Chickens; Duodenum; Electromyography; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Membrane Potentials; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phentolamine; Propranolol; Sincalide; Stomach; Vagotomy | 1993 |
Beta-adrenergic antagonists attenuate somatic and aversive signs of opiate withdrawal.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Avoidance Learning; Male; Naloxone; Narcotics; Propranolol; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1993 |
Brain-death-induced cardiac contractile dysfunction: studies of possible neurohormonal and blood-borne mediators.
Topics: Animals; Arginine; Blood Physiological Phenomena; Blood Pressure; Blood Transfusion; Brain Death; Catecholamines; Endorphins; Heart; Hemodynamics; Male; Myocardial Contraction; Myocardium; Naloxone; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vagotomy | 1994 |
Effects of mu-, delta- and kappa-agonists on isolated right atria of the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Benzomorphans; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Propranolol; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1994 |
[Effects of beta-endorphin on blood pressure and heart rate in rats].
Topics: Amygdala; Animals; beta-Endorphin; Blood Pressure; Female; Heart Rate; Male; Microinjections; Naloxone; Phentolamine; Propranolol; Rats | 1994 |
Cocaine-induced elevation of plasma corticosterone is mediated by different neurotransmitter systems in rats.
Topics: Animals; Atropine; Cocaine; Corticosterone; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Neurotransmitter Agents; Phenoxybenzamine; Pimozide; Propranolol; Rats; Rats, Wistar | 1993 |
[Inhibitory effect of intraventricular administration of morphine on the hyperviscosity and elevation of blood pressure induced by stress in the rat].
Topics: Animals; Blood Pressure; Blood Viscosity; Electroacupuncture; Injections, Intraventricular; Male; Morphine; Naloxone; Phentolamine; Propranolol; Rats; Rats, Wistar; Stress, Physiological | 1993 |
Morphine tolerance and inhibition of oxytocin secretion by kappa-opioids acting on the rat neurohypophysis.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Biological Assay; Drug Tolerance; Electric Stimulation; Female; Injections, Intraventricular; Labor, Obstetric; Lactation; Morphine; Morphine Dependence; Naloxone; Oxytocin; Pituitary Gland, Posterior; Pregnancy; Propranolol; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Vasopressins | 1993 |
Effect of opiate and beta-adrenergic blockers on the gut transit response to mild exercise.
Topics: Administration, Oral; Adult; Exercise Test; Female; Gastrointestinal Transit; Heart Rate; Humans; Hydrocortisone; Hydrogen; Infusions, Intravenous; Injections, Intravenous; Lactulose; Male; Naloxone; Oxygen Consumption; Physical Exertion; Propranolol; Rest; Spirometry; Time Factors | 1993 |
Direct effects of fentanyl on canine coronary artery rings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Intravenous; Animals; Arteries; Calcium Channel Blockers; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Fentanyl; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nifedipine; Prazosin; Propranolol; Vasoconstriction | 1995 |
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride | 1996 |
Neuronal regulation of interleukin 6 secretion in murine spleen: adrenergic and opioidergic control.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analgesics; Animals; beta-Endorphin; Clonidine; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Interleukin-6; Isoproterenol; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Narcotic Antagonists; Neurons; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid; Spleen | 1997 |
Propranolol blocks the stimulatory effects of naloxone on ventilation and oxygen consumption in hamsters.
Topics: Adrenergic beta-Antagonists; Animals; Body Temperature; Cricetinae; Dose-Response Relationship, Drug; Male; Mesocricetus; Naloxone; Oxygen Consumption; Propranolol; Pulmonary Ventilation; Respiration; Tidal Volume | 1997 |
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA Antagonists; Haloperidol; Injections, Intraventricular; Male; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists; Sincalide | 1997 |
On the mechanism(s) of cholecystokinin (CCK): receptor stimulation attenuates morphine dependence in mice.
Topics: Adrenergic Antagonists; Animals; Atropine; Benzazepines; Ceruletide; Dopamine Antagonists; Male; Methysergide; Mice; Morphine; Morphine Dependence; Movement Disorders; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Cholecystokinin; Serotonin Antagonists; Sincalide; Substance Withdrawal Syndrome; Sulpiride | 1997 |
Immunohistochemistry and secretory effects of leucine enkephalin in the isolated pig lacrimal gland.
Topics: Animals; Atropine; Enkephalin, Leucine; Eye Proteins; Female; Immunohistochemistry; In Vitro Techniques; Lacrimal Apparatus; Male; Naloxone; Neurons; Perfusion; Phentolamine; Propranolol; Swine; Theophylline | 1998 |
Involvement of mu-opioid receptors and alpha-adrenoceptors in the immunomodulatory effects of dihydroetorphine.
Topics: Adjuvants, Immunologic; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Cell Division; Etorphine; Female; Immunosuppressive Agents; Interleukin-2; Lymphocytes; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Opioid, mu | 1998 |
Neurotransmitter-mediated open-field behavioral action of CGRP.
Topics: Animals; Atropine; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Exploratory Behavior; Grooming; Haloperidol; Injections, Intraventricular; Locomotion; Male; Methysergide; Motor Activity; Naloxone; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar | 1999 |
Cardiovascular effects of a mu-selective opioid agonist (tyrosine-D-arginine-phenylalanine-lysine-NH2) in fetal sheep: sites and mechanisms of action.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular System; Female; Heart Rate, Fetal; Kinetics; Naloxone; Narcotic Antagonists; Oligopeptides; Pregnancy; Propranolol; Receptors, Opioid, mu; Sheep | 1999 |
The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal.
Topics: Amygdala; Animals; Axonal Transport; Caudate Nucleus; Male; Microinjections; Morphine Dependence; Naloxone; Naltrexone; Neurons; Norepinephrine; Oxidopamine; Propranolol; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thalamus; Tyrosine 3-Monooxygenase | 1999 |
Nociceptin/orphanin FQ increases blood pressure and heart rate via sympathetic activation in sheep.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Catheters, Indwelling; Drug Antagonism; Female; Heart Rate; Infusions, Intravenous; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Phenoxybenzamine; Propranolol; Sheep; Sympathetic Nervous System; Sympatholytics; Vasodilator Agents; Wakefulness | 1999 |
Corticosterone response induced by intracerebroventricular administration of met-enkephalin and naloxone in rats under stress.
Topics: Animals; Corticosterone; Dose-Response Relationship, Drug; Enkephalin, Methionine; Immobilization; Injections, Intraventricular; Male; Naloxone; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Opioid; Stress, Physiological; Yohimbine | 1997 |
Nociceptin modulates renal sympathetic nerve activity through a central action in conscious rats.
Topics: Animals; Atropine; Blood Pressure; Brain; Denervation; Heart Rate; Kidney; Male; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Propranolol; Rats; Rats, Wistar; Sinus of Valsalva; Sympathetic Nervous System | 1999 |
Neural and endocrine mechanisms mediating noxious stimulus-induced inhibition of bradykinin plasma extravasation in the rat.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Electric Stimulation; Endocrine Glands; Hypophysectomy; Knee Joint; Male; Mifepristone; Naloxone; Narcotic Antagonists; Nervous System Physiological Phenomena; Neurons, Afferent; Pain; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sympathetic Nervous System; Synovial Fluid | 1999 |
Norepinephrine modulates single hypothalamic arcuate neurons via alpha(1)and beta adrenergic receptors.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Cromakalim; Female; Glyburide; In Vitro Techniques; Locus Coeruleus; Magnesium; Male; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine | 2000 |
Role of PAG in the antinociception evoked from the medial or central amygdala in rats.
Topics: Adrenergic beta-Antagonists; Amygdala; Anesthetics, Local; Animals; Atropine; Electric Stimulation; Ganglionic Blockers; Lidocaine; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Threshold; Parasympatholytics; Periaqueductal Gray; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists | 2001 |
The central mechanism of the depressor-bradycardia effect of "Tinggong.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bradycardia; Cardiovascular System; Electroacupuncture; Male; Naloxone; Narcotic Antagonists; Prazosin; Propranolol; Rats; Rats, Wistar | 2000 |
The action of orexin A on passive avoidance learning. Involvement of transmitters.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Avoidance Learning; Bicuculline; Carrier Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neuropeptides; Neurotransmitter Agents; Nitric Oxide Synthase; Orexins; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar | 2002 |
The importance of oxytocin mechanisms in the control of mouse parturition.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Gene Expression; Genes, fos; Labor, Obstetric; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxytocin; Pregnancy; Propranolol; Receptors, Opioid, mu; Ritodrine; Stress, Physiological; Supraoptic Nucleus | 2002 |
Involvement of noradrenergic system within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats.
Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Butoxamine; Conditioning, Operant; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Substance Withdrawal Syndrome; Timolol | 2003 |
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine | 2003 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Gene Expression; Genes, fos; Heart Ventricles; Immunohistochemistry; Injections, Subcutaneous; Male; Morphine; Myocytes, Cardiac; Naloxone; Normetanephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Time Factors; Yohimbine | 2004 |
Effects of pituitary adenylate cyclase polypeptide (PACAP) on extinction of active avoidance learning in rats: involvement of neurotransmitters.
Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Bicuculline; Dopamine Antagonists; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Male; Naloxone; Narcotic Antagonists; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nitroarginine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar | 2005 |
Cardiovascular responses to intrathecal administration of endomorphins in anesthetized rats.
Topics: Amino Acid Sequence; Analgesics, Opioid; Anesthesia; Animals; Atropine; Blood Pressure; Cardiovascular System; Female; Heart Rate; Injections, Spinal; Male; Naloxone; NG-Nitroarginine Methyl Ester; Oligopeptides; Phentolamine; Propranolol; Rats; Rats, Wistar; Time Factors | 2007 |
Beta-adrenergic and opioidergic modulation of cortisol secretion in response to acute stress.
Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Animals; Hormones; Hydrocortisone; Isoproterenol; Male; Naloxone; Narcotic Antagonists; Pituitary-Adrenal System; Propranolol; Stress, Physiological; Swine; Swine, Miniature | 2007 |
Antispasmodic effect of Piper nigrum fruit hot water extract on rat ileum.
Topics: Animals; Hot Temperature; Ileum; In Vitro Techniques; Male; Naloxone; NG-Nitroarginine Methyl Ester; Parasympatholytics; Piper nigrum; Plant Extracts; Potassium Channel Blockers; Propranolol; Rats; Rats, Wistar; Water | 2008 |
Ileal relaxation induced by Mentha longifolia (L.) leaf extract in rat.
Topics: Animals; Calcium Chloride; Ileum; Intestines; Male; Mentha; Muscle Relaxation; Muscle, Smooth; Naloxone; NG-Nitroarginine Methyl Ester; Plant Extracts; Plant Leaves; Propranolol; Rats; Rats, Wistar | 2008 |
Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Propranolol; Rats; Rats, Sprague-Dawley; Reflex, Startle; Substance Withdrawal Syndrome; Time Factors | 2009 |
Cardiovascular responses to intravenous injection of a novel isoindolin-1-one derivate in conscious rats.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atropine; Baroreflex; Blood Pressure; Catecholamines; Catheters, Indwelling; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Heart Conduction System; Heart Rate; Isoindoles; Male; Naloxone; Narcotic Antagonists; Parasympatholytics; Piperazines; Propranolol; Rats; Rats, Wistar; Sinoatrial Node; Sympathetic Nervous System; Time Factors | 2009 |
Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Carrageenan; Edema; Hormone Antagonists; Indomethacin; Injections, Spinal; Male; Maprotiline; Mifepristone; Naloxone; Narcotic Antagonists; Prazosin; Propranolol; Rats; Rats, Wistar; Yohimbine | 2010 |
Stress-dependent impairment of passive-avoidance memory by propranolol or naloxone.
Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Male; Memory; Naloxone; Narcotic Antagonists; Propranolol; Rats; Rats, Long-Evans; Receptors, Adrenergic, beta; Receptors, Opioid; Retention, Psychology; Stress, Physiological | 2011 |
Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.
Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Aminoacetonitrile; Animals; Catechol O-Methyltransferase; Corticosterone; Extracellular Signal-Regulated MAP Kinases; Heart; Heart Ventricles; HSP27 Heat-Shock Proteins; Hypothalamo-Hypophyseal System; Male; Morphine; Morphine Dependence; Naloxone; Norepinephrine; Phosphorylation; Pituitary-Adrenal System; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Substance Withdrawal Syndrome | 2012 |
Tramadol inhibits the contractility of isolated human myometrium.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; Isoproterenol; Methylene Blue; Middle Aged; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Potassium Chloride; Propranolol; Receptors, Adrenergic, beta-1; Tramadol; Uterine Contraction | 2013 |
Involvement of transmitters in the anxiolytic action of urocortin 3 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Atropine; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Methysergide; Mice; Naloxone; Neurotransmitter Agents; Propranolol; Time Factors; Urocortins | 2013 |
Stress-dependent opioid and adrenergic modulation of newly retrieved fear memory.
Topics: Adrenergic beta-Antagonists; Animals; Conditioning, Psychological; Fear; Male; Mental Recall; Naloxone; Narcotic Antagonists; Propranolol; Rats; Rats, Long-Evans; Receptors, Adrenergic, beta; Receptors, Opioid; Stress, Psychological | 2014 |
Transmitter mediation of the anxiolytic action of apelin-13 in male mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA-A Receptor Antagonists; Haloperidol; Intercellular Signaling Peptides and Proteins; Male; Maze Learning; Methysergide; Mice; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Receptors, Neurotransmitter; Serotonin Antagonists | 2014 |
Propranolol, but not naloxone, enhances spinal reflex bladder activity and reduces pudendal inhibition in cats.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Animals; Cats; Disease Models, Animal; Electric Stimulation; Female; Male; Muscle Contraction; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neural Inhibition; Propranolol; Pudendal Nerve; Reflex; Spinal Cord Injuries; Spinal Nerves; Tibial Nerve; Urinary Bladder; Urodynamics | 2015 |
Effects and underlying mechanisms of human opiorphin on cardiovascular activity in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart Rate; Humans; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Phentolamine; Propranolol; Rats, Sprague-Dawley; Renin-Angiotensin System; Reserpine; Salivary Proteins and Peptides; Tetrazoles; Valine; Valsartan | 2015 |
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats.
Topics: Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Arginine; Atropine; Bicuculline; Dopamine Antagonists; Exploratory Behavior; Haloperidol; Male; Maze Learning; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nitroso Compounds; Peptide Fragments; Phenoxybenzamine; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar; Receptors, GABA; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Neurotransmitter Mechanisms Underlying Sacral Neuromodulation of Bladder Overactivity in Cats.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Cats; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Indicators and Reagents; Male; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Propranolol; Pyridines; Sacrum; Spinal Cord Stimulation; Spinal Nerve Roots; Thiazoles; Urinary Bladder, Overactive | 2017 |
Role of opioid and β-adrenergic receptors in bladder underactivity induced by prolonged pudendal nerve stimulation in cats.
Topics: Analgesics, Opioid; Animals; Cats; Electric Stimulation; Naloxone; Propranolol; Pudendal Nerve; Receptors, Adrenergic, beta; Reflex; Urinary Bladder; Urinary Bladder Diseases | 2023 |