Page last updated: 2024-08-16

propranolol and n-desisopropylpropranolol

propranolol has been researched along with n-desisopropylpropranolol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's4 (30.77)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Bischoff-Kont, I; Chaikuad, A; Faudone, G; Fürst, R; Heering, J; Kaiser, A; Knapp, S; Merk, D; Rachor, L; Willems, S; Zhubi, R1
Privitera, PJ; Sealens, DA; Walle, T1
Cahill, CM; Harrison, PM; McLean, AJ; Tonkin, AM1
Lo, MW; Riegelman, S; Silber, B1
Hermansson, J; Lind, M; von Bahr, C1
Eto, S; Jitsufuchi, N; Kudo, K; Noda, A; Noda, H; Ono, Y; Wu, X1
Bichara, N; Blake, CL; Ching, MS; Ghabrial, H; Smallwood, RA; Tukey, RH1
Imai, M; Isayama, Y; Nasa, Y; Noda, A; Noda, H; Ono, Y; Sera, N; Takeo, S; Wu, X1
Noda, A; Noda, H; Ono, Y; Wu, X1
Imamura, Y; Noda, A; Noda, H; Wu, X2
Chan, E; Chen, J; Chen, X; Duan, W; Ee, PL; Guan, YY; Hong, YH; Huang, M; Zhao, LZ; Zhou, S1
Hanioka, N; Nagaoka, K; Narimatsu, S; Shimizudani, T; Yamano, S1

Other Studies

13 other study(ies) available for propranolol and n-desisopropylpropranolol

ArticleYear
Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells.
    Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioblastoma; HEK293 Cells; Humans; Molecular Structure; Orphan Nuclear Receptors; Propranolol; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2021
Quantitative determination of propranolol, propranolol glycol and N-desisopropylpropranolol in brain tissue by electron capture gas chromatography.
    Journal of chromatography, 1976, Jul-21, Volume: 123, Issue:1

    Topics: Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Gas; Mass Spectrometry; Mice; Oxprenolol; Propranolol; Solvents; Trifluoroacetic Acid

1976
Rapid and simultaneous extraction of propranolol, its neutral and basic metabolites from plasma and assay by high-performance liquid chromatography.
    Journal of chromatography, 1985, Oct-11, Volume: 343, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Hydrolysis; Propranolol

1985
An automated HPLC method for the assay of propranolol and its basic metabolites in plasma and urine.
    Journal of chromatographic science, 1982, Volume: 20, Issue:3

    Topics: Chromatography, High Pressure Liquid; Humans; Propranolol

1982
Oxidation of (R)- and (S)-propranolol in human and dog liver microsomes. Species differences in stereoselectivity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:2

    Topics: Adult; Animals; Dogs; Glucuronates; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Middle Aged; Oxidation-Reduction; Propranolol; Species Specificity; Stereoisomerism

1982
Determination and properties of acetyl conjugate of N-desisopropylpropranolol, AcNDP.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:10

    Topics: Acetamides; Adult; Animals; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Middle Aged; Propanolamines; Propranolol; Rats

1995
Propranolol 4- and 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:6

    Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Humans; Hydroxylation; Microsomes, Liver; Molecular Conformation; Propranolol

1996
beta-Adrenoreceptor antagonistic actions and mutagenicities of R(+)- and S(-)-enantiomers of N-desisopropylpropranolol and its N-acetyl conjugate.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Mutagens; Propanolamines; Propranolol; Rats; Rats, Wistar; Stereoisomerism

1997
Enantioselective N-acetylation of N-desisopropylpropranolol by rat liver acetyltransferase.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:12

    Topics: 4-Aminobenzoic Acid; Acetylation; Acetyltransferases; Animals; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liver; Male; Molecular Conformation; Propranolol; Rats; Rats, Wistar

1998
Side-chain metabolism of propranolol: involvement of monoamine oxidase and aldehyde reductase in the metabolism of N-desisopropylpropranolol to propranolol glycol in rat liver.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 129, Issue:4

    Topics: Aldehyde Reductase; Aldehydes; Animals; Cell Culture Techniques; Hepatocytes; Liver; Male; Monoamine Oxidase; Oxidation-Reduction; Propranolol; Rats; Rats, Wistar

2001
Side-chain metabolism of propranolol: involvement of monoamine oxidase and mitochondrial aldehyde dehydrogenase in the metabolism of N-desisopropylpropranolol to naphthoxylactic acid in rat liver.
    Life sciences, 2002, Apr-19, Volume: 70, Issue:22

    Topics: Aldehyde Reductase; Aldehydes; Animals; Antidotes; Cell Culture Techniques; Chromatography, High Pressure Liquid; Cyanamide; Cytosol; Fomepizole; Hepatocytes; Lactates; Liver; Male; Mitochondria, Liver; Monoamine Oxidase; Oxidation-Reduction; Propranolol; Pyrazoles; Rats; Rats, Wistar; Stereoisomerism

2002
Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats.
    Current drug metabolism, 2006, Volume: 7, Issue:6

    Topics: Animals; Atrial Natriuretic Factor; Cytochrome P-450 Enzyme System; Drug Interactions; Ginkgo biloba; Liver; Male; Plant Extracts; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley

2006
Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys.
    Chemico-biological interactions, 2010, Jan-05, Volume: 183, Issue:1

    Topics: Animals; Antibodies; Callithrix; Cytochrome P-450 Enzyme System; Humans; Intestine, Small; Kinetics; Liver; Macaca fascicularis; Microsomes; Oxidation-Reduction; Propranolol; Stereoisomerism

2010