Page last updated: 2024-08-16

propranolol and morphine

propranolol has been researched along with morphine in 211 studies

Research

Studies (211)

TimeframeStudies, this research(%)All Research%
pre-1990137 (64.93)18.7374
1990's25 (11.85)18.2507
2000's25 (11.85)29.6817
2010's24 (11.37)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Jolivette, LJ; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Blanchfield, JT; Mansfeld, FM; Smith, MT; Toth, I; Varamini, P; Wyse, BD1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arranz-Gibert, P; Ballet, S; Chevillard, L; Chung, NN; Dyniewicz, J; Guillemyn, K; Kosson, P; Lagard, C; Lipkowski, AW; Megarbane, B; Mika, J; Przewlocka, B; Rojewska, E; Schiller, PW; Simonin, F; Starnowska, J; Teixidó, M; Tourwé, D; Utard, V1
Aldunate, J; Mardones, J; Yojay, L1
Menon, AM; Pleuvry, BJ1
Cowan, A; Macfarlane, IR1
Berkowitz, BA1
Davis, WM; Hatoum, NS1
Audet, J; Martin, JB; Saunders, A1
Boyman, R; Korczyn, AD; Shifter, L1
Bantutova, I1
Fischer, K; Hamprecht, B; Reiser, G; Traber, J1
Navarro, G; Richardson, R; Zuban, AT1
Askew, WE; Charalampous, KD1
Kameyama, T; Nabeshima, T; Ukai, M1
Marsh, JD; Swain, JA; Vatner, SF1
Harada, Y; Kuraishi, Y; Satoh, M; Takagi, H1
Clissiounis, N1
Birkhahn, J; Kisin, I; Markiewicz, W1
Blum, K; Hamilton, MG; Hirst, M1
Angelucci, L; Valeri, P1
Franklin, D; Kemper, WS; Ross, J; Sasyama, S; Theroux, P1
Ferri, S; Reina, R; Santagostino, A1
Cools, AR1
Broekkamp, CL; Cools, AR; Gieles, LC; Megens, A; Mortiaux, HJ1
Bragg, DA; Edmonds, CH; Hibbs, CW; Keats, AS; Slogoff, S1
James, TN; Urthaler, F; Walker, AA1
Agid, R; Sable-Amplis, R2
Estler, CJ; Fulle, P1
Hill, DF; Roberts, S; von Hungen, K1
Anggård, E; Eriksson, JH; Holmstrand, J; Jacob, RG1
Brooks, SN; Campbell, WB; Keeton, K; Pettinger, WA; Tanaka, K1
Takemori, AE; Tulunay, FC; Yano, I1
Heimanes, RL1
Burks, TF; VanInwegen, RG1
Nikol'skaia, MG; Samonina, GE; Udel'nov, MG1
Winter, JC2
Nichimura, T; Sakamoto, M; Sasao, T; Yanaura, S1
Carol, M; Jacquet, YF; Russell, IS1
Takagi, K; Takayanagi, I; Terawaki, Y1
Kaneto, H; Ohta, A1
Kaneto, H; Okada, T; Takahashi, M1
Boura, AL; King, RG; Rechtman, MP1
Barney, CC; Katovich, MJ; Pitman, DL1
Inoue, M; Kaneto, H1
Camilleri, M; Malagelada, JR; Thomforde, GM; Yaksh, TL1
Hernandez, J; Laorden, ML; Romero, M; Serrano, JS1
Datta, H; Saha, N; Sharma, PL1
Gitter, S; Oron, Y; Sagy, M; Sarne, Y; Shavit, G; Vidne, BA1
Couture, R; Hasséssian, H1
Gregor, L; Thornhill, JA; Townsend, C1
Inoue, M; Kaneto, H; Kihara, T1
Allen, LG; Crowley, WR; Kalra, SP1
O'Neill, KA; Valentino, D1
Bentley, GA; Starr, J1
Ishizuka, J; Ono, T; Sasaki, M; Toyota, T; Yanaihara, C; Yanaihara, N1
Moffitt, EA; Sethna, DH1
Kalin, NH; Shelton, SE1
Gala, RR; Haisenleder, DJ1
Kroneberg, G; Oberdorf, A1
Castellanos, DE; Giavedoni, E; Landaburu, RH; Lo Presti, CA1
Estler, CJ1
Braunwald, E; Gomoll, AW1
Bell, S; Jhamandas, K; Sutak, M1
Cicero, TJ; Meyer, ER; Smithloff, BR1
Cicero, TJ1
Jindal, MN; Kelkar, VV; Patel, VK; Shah, UH1
Brunk, SF; Delle, M; Wilson, WR1
Bonta, IL; Frankhuyzen, AL1
Talalaenko, AN2
Dhumal, VR; Gulati, OD; Raghunath, PR; Sivaramakrishna, N1
Kisin, IE1
Gourley, DR1
Heller, B; Saavedra, JM1
Fischer, K; Hamprecht, B; Latzin, S; Traber, J1
Almirante, L; Murmann, W; Saccani-Guelfi, M1
Dhalla, NS1
Lang, WJ; Pearson, L; Rush, ML1
Khairallah, PA; Türker, RK1
Kaplan, HR; Laforce, S; Robson, RD1
Dewey, WL; Harris, LS; Howes, JF; Nuite, JA1
Fennessy, MR; Lee, JR1
Amend, JF; Hoff, HE1
Castillo, S; Contreras, E; Quijada, L1
Dhasmana, KM; Dixit, KS; Gupta, ML; Jaju, BP1
Aihara, H; Kasai, A; Sakai, T1
Sapeika, N; Zwarenstein, H1
Chahl, LA; O'Donnell, SR1
Hermansen, K; Larsen, JJ1
Black, WC; Grosz, HJ1
Peterson, GR; Shuster, L; Webster, GW1
Ishida, Y; Takagi, K; Takayanagi, I1
Correa, FM; Graeff, FG1
Ayres, SM; Evans, RG; Mueller, HS; Religa, A1
Capone, RJ; Mansour, EJ; Mason, DT; Zelis, R1
DeFeudis, FV; Grosz, HJ1
Larvor, P; Rayssiguier, Y1
De Groat, WC; Saum, WR1
Bartlet, AL1
Fontaine, J; Reuse, JJ1
Krstíc, MK1
Chiba, S1
Bocage, AJ; Harris, AS; Otero, H1
Brahamankar, DM; Chopde, CT; Dorle, AK; Sohel, MS1
Eades, CG; Flanary, HG; Martin, WR; Thompson, JA; Thompson, WO1
Irikura, T; Iwaki, R1
Nager, F1
Ancill, RJ; Jackson, DM; Redfern, PH1
Sinclair, JG1
Hatch, RC1
Christensen, J; Wienbeck, M1
Ueda, S1
Takagi, K; Takayanagi, I1
Komissarov, IV; Talalaenko, AN2
Muraki, T1
Fedorova, IB1
Lambert, GA; Lang, WJ1
Levitsky, S; Morrow, AG; Mullin, EM; Sloane, RE1
Ingemarsson, I; Liedberg, G; Persson, C1
Whittle, BA1
Kosterlitz, HW; Watt, AJ1
Demeester, G; Lacroix, E; Leusen, I1
Sanders, HD1
Hamlin, RL; Smetzer, DL; Smith, CR1
Kennedy, BL; West, TC1
Ahn, NC; Berthelsen, P; Eriksen, J; Rasmussen, JP2
File, SE1
Berthelsen, P; Eriksen, J; Rasmussen, JP; Strøm, J1
Clarke, G; Pill, CE; Wright, DM1
Kehlet, H1
Han, JS; Li, SJ; Tang, J; Zhang, HX1
Kameyama, T; Nagasaka, M1
Wallenstein, MC2
Järbe, TU1
Desplanches, D; Favier, R; Flandrois, R; Frutoso, J; Grandmontagne, M1
Bhargava, KP; Mishra, N; Pant, KK; Singh, N; Sinha, JN; Verma, VK1
Dong, ZT; Jiang, WD1
Bluet-Pajot, MT; Durand, D; Kordon, C; Mounier, F; Schaub, C1
Gowdey, CW; Hirst, M; Tepperman, FS1
Jaju, BP; Pant, KK; Srivastava, VK1
Altura, BM; Chand, N1
Maroko, PR1
Hasegawa, T; Maeda, Y; Nabeshima, T; Yamada, K1
Laorden, ML; Micol, JA1
Burhol, PG; Johansen, O; Jorde, R; Reikerås, O; Tveita, T; Tønnesen, T1
Guo, XQ; Guo, Z; Liang, ZJ; Zhao, YM1
Bicknell, RJ; Coombes, JE; Leng, G; Russell, JA1
Hill, MR; Levy, MN; Martin, PJ; Wallick, DW1
Hyltander, A; Körner, U; Lundholm, KG1
du Mée, CP; Lam, XM; Ward, CA1
Gibert-Rahola, J; Maldonado, R; Micó, JA; Valverde, O1
Baan, J; Boekkooi, PF; Rudolph, AM; Teitel, DF1
de Silva, R; Iida, H; Jones, T; Lammertsma, AA; Maseri, A; Rhodes, CG; Yamamoto, Y1
Lin, Q; Peng, YB; Willis, WD1
Ansell, RJ; Mosbach, K; Ramström, O1
Bayer, BM; Dretchen, KL; Flores, LR1
Azizi, N; Rezayat, M; Zarrindast, MR1
Drewe, J; Fricker, G; Gutmann, H; Huwyler, J; Thöle, M1
Harvey, PJ; Hickey, HM; Le Couteur, DG; McLean, AJ1
Chen, JY; Dafny, N; Kang, YM; Ouyang, W; Qiao, JT1
Goto, T; Ochi, T1
Douglas, AJ; Leng, G; Russell, JA1
Guo, SY; Hisamitsu, T; Jiao, YY; Okada, M; Umezawa, T1
Zhou, W; Zhu, H1
Maeda, A; Minami, M; Nakagawa, T; Satoh, M; Watanabe, T; Yamamoto, R1
Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR1
Bhaskaran, M; Bhat, RS; Hitosugi, N; Mongia, A; Singhal, PC1
Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV1
Drewe, J; Fux, I; Gutmann, H; Kusch-Poddar, M1
Lychkova, AE1
Franklin, KB; Robinson, MJ2
Chen, YM; He, J; Ma, YY; Wang, JH; Zhang, J1
Gewirtz, JC; Rothwell, PE; Thomas, MJ1
Franklin, KB; Robinson, MJ; Ross, EC1
Creamer, M; Fletcher, S; Forbes, D1
Hu, XT; Liu, C; Ma, YY; Mao, Y; Yang, SC1
Li, Y; Sui, N; Wu, Y; Yang, X1
Willyard, C1
Almela, P; Hurle, MA; Laorden, ML; Martínez-Laorden, E; Milanés, MV1
Carlson, S; Chen, Y; Hu, X; Li, L; Ma, Y; Wang, J1
Nasehi, M; Oryan, S; Valizadegan, F; Zarrindast, MR1
Li, X; Wei, S1
Roque, AP1
Fakhrzad, A; Khosravani, E; Moezi, L; Shafaroodi, H1

Reviews

7 review(s) available for propranolol and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Methadone; Morphine; Morphine Dependence; Naloxone; Propranolol; Protein Binding; Sex Factors; Substance-Related Disorders

1976
The coronary circulation and myocardial oxygenation in coronary artery disease: effects of anesthesia.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:4

    Topics: Anesthesia; Calcium Chloride; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Digoxin; Dobutamine; Drug Combinations; Enflurane; Fentanyl; Halothane; Hemodynamics; Humans; Isoflurane; Monitoring, Physiologic; Morphine; Myocardium; Nitroglycerin; Nitroprusside; Nitrous Oxide; Oxygen Consumption; Propranolol; Protamines

1986
[Effect of pharmacological substances on the blood supply and work of the heart].
    Kardiologiia, 1969, Volume: 9, Issue:6

    Topics: Animals; Antithyroid Agents; Blood Flow Velocity; Coronary Disease; Coronary Vessels; Dipyridamole; Ganglionic Blockers; Heart; Morphine; Myocardium; Nitroglycerin; Oxygen; Papaverine; Partial Pressure; Phenothiazines; Prenylamine; Propranolol; Reserpine; Sympatholytics; Vasodilator Agents; Veins

1969
Preventing post traumatic stress disorder: are drugs the answer?
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:12

    Topics: Anti-Anxiety Agents; Ethanol; Humans; Hydrocortisone; Morphine; Propranolol; Stress Disorders, Post-Traumatic

2010
Pharmacotherapy as prophylactic treatment of post-traumatic stress disorder: a review of the literature.
    Issues in mental health nursing, 2015, Volume: 36, Issue:9

    Topics: Adrenergic beta-Antagonists; Drug Therapy; Humans; Hydrocortisone; Morphine; Premedication; Propranolol; Stress Disorders, Post-Traumatic; Treatment Outcome

2015

Trials

4 trial(s) available for propranolol and morphine

ArticleYear
Propranolol in the treatment of opiate dependence -- a controlled study.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Euphoria; Female; Heart Rate; Humans; Male; Methadone; Morphine; Morphine Dependence; Narcotic Antagonists; Placebos; Propranolol; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
Propranolol in the treatment of acute myocardial infarction. Effect on myocardial oxygenation and hemodynamics.
    Circulation, 1974, Volume: 49, Issue:6

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Catheterization; Cardiac Output; Clinical Trials as Topic; Coronary Circulation; Elasticity; Female; Glucose; Heart Rate; Humans; Lactates; Lidocaine; Male; Meperidine; Middle Aged; Morphine; Myocardial Infarction; Myocardium; Oxygen Consumption; Propranolol; Pyruvates; Vascular Resistance

1974
The cardiovascular effects of morphine. The peripheral capacitance and resistance vessels in human subjects.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:6

    Topics: Adult; Arteries; Atropine; Blood Pressure; Blood Vessels; Central Venous Pressure; Clinical Trials as Topic; Edrophonium; Hemodynamics; Histamine; Humans; Middle Aged; Morphine; Norepinephrine; Placebos; Plethysmography; Promethazine; Propranolol; Regional Blood Flow; Vascular Resistance; Veins; Venous Pressure

1974
Evaluation of mechanisms behind elevated energy expenditure in cancer patients with solid tumours.
    European journal of clinical investigation, 1993, Volume: 23, Issue:1

    Topics: Basal Metabolism; Energy Metabolism; Female; Hormones; Humans; Indomethacin; Male; Morphine; Neoplasms; Oxygen Consumption; Propranolol; Receptors, Adrenergic, beta; Weight Loss

1993

Other Studies

200 other study(ies) available for propranolol and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Synthesis and biological evaluation of an orally active glycosylated endomorphin-1.
    Journal of medicinal chemistry, 2012, Jun-28, Volume: 55, Issue:12

    Topics: Absorption; Administration, Oral; Analgesics, Opioid; Animals; Chemistry Techniques, Synthetic; CHO Cells; Constipation; Cricetinae; Cricetulus; Glycosylation; Male; Naloxone; Narcotic Antagonists; Neuralgia; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain.
    Journal of medicinal chemistry, 2016, 04-28, Volume: 59, Issue:8

    Topics: Acute Disease; Amino Acid Sequence; Animals; Behavior, Animal; Blood-Brain Barrier; Cell Membrane Permeability; Humans; Ligands; Male; Mice; Narcotic Antagonists; Neuralgia; Nociceptin Receptor; Pain Management; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid

2016
Studies on the mechanism of the action of morphine on the peristalsis of guinea pig ileum in situ.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 291, Issue:4

    Topics: Animals; Dihydroxyphenylalanine; Female; Gastrointestinal Motility; Guanethidine; Guinea Pigs; Hexamethonium Compounds; Ileum; Isoproterenol; Male; Morphine; Peristalsis; Phentolamine; Pressure; Propranolol; Receptors, Adrenergic; Reserpine

1975
A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:11

    Topics: Adrenalectomy; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Hypothermia; Male; Meperidine; Mice; Morphine; Naloxone; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Reserpine; Species Specificity

1976
Effect of propranolol on antinociceptive, tolerance- and dependence-producing properties of morphine in rodents and monkeys.
    European journal of pharmacology, 1975, Volume: 34, Issue:1

    Topics: Analgesics, Opioid; Animals; Drug Interactions; Drug Tolerance; Female; Haplorhini; Humans; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Practolol; Propranolol; Rats; Reaction Time; Stereoisomerism; Substance Withdrawal Syndrome; Time Factors

1975
Lethal synergism between morphine or other narcotic analgesics and propranolol.
    Toxicology, 1979, Volume: 14, Issue:2

    Topics: Analgesics, Opioid; Animals; Dogs; Drug Synergism; Female; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Morphine; Propranolol; Rats; Stereoisomerism

1979
Effects of somatostatin and hypothalamic ventromedial lesions on GH release induced by morphine.
    Endocrinology, 1975, Volume: 96, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Fenclonine; Growth Hormone; Growth Hormone-Releasing Hormone; Hypothalamus; Male; Methyltyrosines; Morphine; Peptides; Phenoxybenzamine; Propranolol; Rats; Stimulation, Chemical

1975
Morphine mydriasis in mice.
    Life sciences, 1979, Apr-30, Volume: 24, Issue:18

    Topics: Animals; Fenclonine; Haloperidol; Male; Mice; Mice, Inbred ICR; Morphine; Mydriatics; Propranolol; Pupil; Sympathectomy

1979
[Effect of pharmacological agents and coagulation of the n. raphe dorsalis on morphine effects].
    Eksperimentalna meditsina i morfologiia, 1979, Volume: 18, Issue:4

    Topics: Animals; Brain Stem; Catalepsy; Cyproheptadine; Dimenhydrinate; Electrocoagulation; Female; Fenclonine; Fever; Haloperidol; Humans; Lysergic Acid Diethylamide; Morphine; Propranolol; Raphe Nuclei; Rats; Receptors, Serotonin; Time Factors

1979
Measurements of adenosine 3':5'-cyclic monophosphate and membrane potential in neuroblastoma times glioma hybrid cells: opiates and adrenergic agonists cause effects opposite to those of prostaglandin E1.
    FEBS letters, 1975, Apr-01, Volume: 52, Issue:2

    Topics: Animals; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Glioma; Haloperidol; Hybrid Cells; Isoproterenol; Membrane Potentials; Mice; Morphine; Narcotics; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Prostaglandins; Rats; Sympatholytics

1975
Propranolol and morphine.
    Psychopharmacology, 1976, Dec-21, Volume: 51, Issue:1

    Topics: Animals; Lethal Dose 50; Male; Mice; Morphine; Propranolol; Receptors, Adrenergic, beta; Seizures; Sotalol

1976
Cerebellar cAMP levels following acute and chronic morphine administration.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cerebellum; Cyclic AMP; Humans; Male; Mice; Morphine; Morphine Dependence; Propranolol

1977
Effects of catecholaminergic or tryptaminergic agents on the morphine-induced Straub tail reaction.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Central Nervous System; Ditiocarb; Drug Synergism; Female; Haloperidol; Mice; Morphine; Motor Activity; Propranolol; Serotonin; Spinal Cord; Tail; Tryptamines

1978
Effects of morphine on coronary and left ventricular dynamics in conscious dogs.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:2

    Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Consciousness; Coronary Circulation; Dogs; Heart Rate; Heart Ventricles; Hydrogen-Ion Concentration; Isoproterenol; Morphine; Norepinephrine; Oxygen; Phenoxybenzamine; Phentolamine; Propranolol; Respiration; Vascular Resistance

1975
Antagonism by phenoxybenzamine of the analgesic effect of morphine injected into the nucleus reticularis gigantocellularis of the rat.
    Neuropharmacology, 1979, Volume: 18, Issue:1

    Topics: Animals; Injections; Male; Medulla Oblongata; Methysergide; Morphine; Phenoxybenzamine; Propranolol; Rats; Time Factors

1979
Effect of adrenergic drugs on morphine-induced hyperglycemia.
    Life sciences, 1979, Jul-23, Volume: 25, Issue:4

    Topics: Animals; Dihydroergotoxine; Female; Hyperglycemia; Iproniazid; Male; Monoamine Oxidase Inhibitors; Morphine; Nialamide; Propranolol; Rabbits; Sympathomimetics; Tranylcypromine

1979
Effect of large doses of morphine on experimental myocardial ischemia in cats.
    Israel journal of medical sciences, 1979, Volume: 15, Issue:7

    Topics: Animals; Blood Pressure; Cats; Coronary Circulation; Coronary Disease; Electrocardiography; Heart Rate; Morphine; Nitrous Oxide; Propranolol

1979
Opiate-like activity of salsolinol on the electrically stimulated guinea pig ileum.
    Life sciences, 1979, Dec-24, Volume: 25, Issue:26

    Topics: Animals; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Isoquinolines; Male; Morphine; Muscle Contraction; Muscle, Smooth; Narcotics; Phentolamine; Propranolol; Salsoline Alkaloids

1979
Influence of social environment and of drugs on 3H-corticosterone uptake in various brain areas.
    Annali dell'Istituto superiore di sanita, 1978, Volume: 14, Issue:1

    Topics: Animals; Brain; Chlorpromazine; Corticosterone; Female; Humans; Limbic System; Male; Metergoline; Mice; Morphine; Naloxone; Propranolol; Rats; Receptors, Glucocorticoid; Receptors, Steroid; Social Environment; Stress, Psychological; Tritium

1978
Regional Myocardial function in the conscious dog during acute coronary occlusion and responses to morphine, propranolol, nitroglycerin, and lidocaine.
    Circulation, 1976, Volume: 53, Issue:2

    Topics: Animals; Coronary Disease; Dogs; Heart; Heart Rate; Lidocaine; Morphine; Nitroglycerin; Propranolol

1976
Dopamine and the depressant action of morphine on stimulated guinea-pig ileum.
    British journal of pharmacology, 1977, Volume: 59, Issue:1

    Topics: Animals; Apomorphine; Dopamine; Electric Stimulation; Female; Guinea Pigs; Hydroxydopamines; Ileum; Male; Morphine; Muscle Contraction; Naloxone; Phentolamine; Propranolol

1977
Noradrenergic mechanisms within the raphe and the development of partial tolerance to morphine in cats.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Animals; Behavior, Animal; Brain; Drug Tolerance; Morphine; Norepinephrine; Propranolol; Rats; Time Factors

1977
Site of action of development of partial tolerance to morphine in cats.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:1

    Topics: Animals; Behavior, Animal; Brain Mapping; Brain Stem; Cats; Drug Tolerance; Lypressin; Morphine; Norepinephrine; Propranolol; Raphe Nuclei; Receptors, Adrenergic

1977
Failure of general anesthesia to potentiate propranolol activity.
    Anesthesiology, 1977, Volume: 47, Issue:6

    Topics: Anesthesia, Intravenous; Animals; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart; Hemodynamics; Isoproterenol; Morphine; Propranolol; Sympathetic Nervous System

1977
Comparison of the inotropic action of morphine and ketamine studied in canine cardiac muscle.
    The Journal of thoracic and cardiovascular surgery, 1976, Volume: 72, Issue:1

    Topics: Animals; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Heart Ventricles; Ketamine; Male; Morphine; Myocardial Contraction; Propranolol; Reserpine; Stimulation, Chemical

1976
Effect of aminoglutethimide and adreno-blocking agents on morphine-induced hyperglycemia.
    Biochemical pharmacology, 1976, Aug-15, Volume: 25, Issue:16

    Topics: Adrenal Glands; Aminoglutethimide; Animals; Blood Glucose; Depression, Chemical; Morphine; Phentolamine; Propranolol; Rabbits; Time Factors

1976
Effects of antagonists of adrenaline recepotrs and dopamine receptors and dopamine receptors on morphine-stimulated glycogen breakdown in mouse brain.
    Journal of neurochemistry, 1976, Volume: 27, Issue:2

    Topics: Animals; Brain; Glycogen; Male; Mice; Morphine; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Adrenergic

1976
Serotonin-sensitive adenylate cyclase activity of immature rat brain.
    Brain research, 1975, Feb-07, Volume: 84, Issue:2

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Adenylyl Cyclases; Animals; Animals, Newborn; Cell-Free System; Chlorpromazine; Cyproheptadine; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Haloperidol; In Vitro Techniques; Inferior Colliculi; Lysergic Acid Diethylamide; Methysergide; Morphine; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Serotonin; Serotonin Antagonists; Superior Colliculi; Tryptamines

1975
Renin release, an artifact of anesthesia and its implications in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:3

    Topics: Aldosterone; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Chloralose; Cyclopropanes; Ethyl Ethers; Halothane; Heart Rate; Ketamine; Male; Methoxyflurane; Morphine; Nitrous Oxide; Pentobarbital; Propranolol; Rats; Renin; Urethane

1975
Differential effects on morphine analgesia and naloxone antagonism by biogenic amine modifiers.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Animals; Atropine; Biogenic Amines; Brain; Dopamine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Physostigmine; Propranolol; Receptors, Drug; Serotonin

1975
Catecholamines and the actions of morphine on the guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:1

    Topics: Animals; Catecholamines; Dopamine; Droperidol; Drug Tolerance; Electric Stimulation; Female; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Norepinephrine; Phentolamine; Propranolol; Reserpine

1975
Phentolamine inhibition of morphine induced hyperthermia in cats.
    Proceedings of the Western Pharmacology Society, 1975, Volume: 18

    Topics: Animals; Cats; Female; Fever; Haloperidol; Hydroxydopamines; Male; Morphine; Phentolamine; Propranolol; Time Factors

1975
[Participation of the cardiac sympathetic innervation in the occurrence of vagotomic and atropine tachycardia in anesthetized dogs].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1975, Volume: 61, Issue:10

    Topics: Animals; Atropine; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Ligation; Male; Morphine; Nerve Block; Pentobarbital; Procaine; Propranolol; Sympathetic Nervous System; Urethane; Vagotomy; Vagus Nerve

1975
The stimulus properties of morphine and ethanol.
    Psychopharmacologia, 1975, Nov-21, Volume: 44, Issue:3

    Topics: Animals; Conditioning, Operant; Dextrorphan; Discrimination, Psychological; Ethanol; Female; Levorphanol; Morphine; Naloxone; Pharmaceutical Preparations; Propranolol; Rats; Sodium Chloride; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship

1975
The role of bronchoconstriction in cough reflex.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:6

    Topics: Airway Resistance; Animals; Antitussive Agents; Bronchi; Bronchial Spasm; Bronchodilator Agents; Codeine; Cough; Dogs; Ethanolamines; Female; Isoproterenol; Male; Morphine; Phenylacetates; Picolines; Piperidines; Propranolol

1975
Morphine-induced rotation in naive, nonlesioned rats.
    Science (New York, N.Y.), 1976, Apr-16, Volume: 192, Issue:4236

    Topics: Analgesia; Animals; Atropine; Behavior, Animal; Dopamine; Locomotion; Male; Morphine; Motor Activity; Norepinephrine; Phentolamine; Pimozide; Propranolol; Rats; Reticular Formation

1976
Effects of 5-hydroxytryptamine and morphine on the stomach motility in situ.
    Japanese journal of pharmacology, 1976, Issue:1

    Topics: Acetylcholine; Anesthesia; Animals; Cats; Epinephrine; Female; Gastrointestinal Motility; Guinea Pigs; Male; Morphine; Pentobarbital; Phentolamine; Propranolol; Rabbits; Serotonin; Species Specificity; Time Factors

1976
Beta-blockade of morphine-induced hyperlactacidemia in rabbits.
    Experientia, 1976, May-15, Volume: 32, Issue:5

    Topics: Animals; Drug Antagonism; Lactates; Male; Morphine; Phentolamine; Propranolol; Rabbits

1976
Development of physical dependence on morphine not accompanied with tolerance formation.
    Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:8

    Topics: Analgesia; Animals; Drug Interactions; Drug Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Naloxone; Phentolamine; Propranolol

1992
Differential roles of the adrenal gland in the suppression of morphine antinociceptive tolerance development by alpha- and beta-adrenergic blockers.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Animals; Dexamethasone; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Phentolamine; Propranolol

1991
Hypothermia augments non-cholinergic neuronal bronchoconstriction in pithed guinea-pigs.
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Atropine; Azepines; Body Temperature; Bronchoconstriction; Capsaicin; Decerebrate State; Electric Stimulation; Guinea Pigs; Male; Morphine; Ouabain; Pentolinium Tartrate; Propranolol; Pyrilamine; Spinal Cord; Substance P; Sympathetic Nervous System; Tubocurarine

1991
Mechanisms mediating the thermal response to morphine withdrawal in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1990, Volume: 193, Issue:2

    Topics: Adrenal Glands; Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Female; Morphine; Naloxone; Propranolol; Rats; Receptors, Adrenergic; Skin Temperature; Substance Withdrawal Syndrome

1990
Action site of adrenergic blockers to suppress the development of tolerance to morphine analgesia.
    Brain research, 1990, Jan-15, Volume: 507, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesia; Animals; Drug Tolerance; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Phentolamine; Propranolol; Receptors, Adrenergic; Spinal Cord

1990
Demonstration of intrathecal and systemic morphine and ST-91 effects on fed canine upper gut motility.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Drug Interactions; Eating; Gastrointestinal Motility; Injections, Intravenous; Injections, Spinal; Morphine; Naloxone; Phentolamine; Propranolol

1990
Evidence for involvement of catecholamines in the effect of morphine on ventricular automaticity in the rat.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:2

    Topics: Animals; Drug Interactions; Female; Heart; In Vitro Techniques; Male; Morphine; Naloxone; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Ventricular Function, Right

1991
Effects of morphine on memory: interactions with naloxone, propranolol and haloperidol.
    Pharmacology, 1991, Volume: 42, Issue:1

    Topics: Animals; Dopamine; Haloperidol; Male; Memory; Mice; Mice, Inbred ICR; Morphine; Naloxone; Propranolol; Sympathetic Nervous System

1991
Nonopiate effect of naloxone on cardiac muscle contractility.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:6

    Topics: Animals; Heart; Heart Atria; Humans; In Vitro Techniques; Injections; Morphine; Myocardial Contraction; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stroke Volume

1987
Cardiovascular responses induced by intrathecal substance P in the conscious freely moving rat.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:4

    Topics: Adrenalectomy; Animals; Behavior, Animal; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Injections, Spinal; Male; Morphine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Substance P; Sympathetic Nervous System

1989
Intravenous morphine infusion (IMF) to drug-naive, conscious rats evokes bradycardic, hypotensive effects, but pressor actions are elicited after IMF to rats previously given morphine.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:3

    Topics: Animals; Atropine; Blood Pressure; Guanethidine; Heart Rate; Infusions, Intravenous; Male; Morphine; Naloxone; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Time Factors

1989
Adrenergic function and the development of analgesic tolerance to morphine.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:4

    Topics: Analgesics; Animals; Drug Tolerance; Male; Mice; Morphine; Phentolamine; Propranolol; Sympathetic Nervous System; Time Factors

1989
Interactions between neuropeptide Y and adrenergic systems in the stimulation of luteinizing hormone release in steroid-primed ovariectomized rats.
    Endocrinology, 1987, Volume: 121, Issue:6

    Topics: Animals; Estradiol; Female; Luteinizing Hormone; Morphine; Neuropeptide Y; Ovariectomy; Phenoxybenzamine; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Opioid; Yohimbine

1987
Chronic desipramine attenuates morphine analgesia.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Animals; Desipramine; Drug Interactions; Male; Mice; Morphine; Naloxone; Naltrexone; Propranolol; Reaction Time

1986
The antinociceptive action of some beta-adrenoceptor agonists in mice.
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analgesics; Animals; Dopamine; Drug Interactions; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Narcotics; Piperoxan; Propranolol

1986
Inhibitory effects of rimorphin and dynorphin on insulin secretion from the isolated, perfused rat pancreas.
    The Tohoku journal of experimental medicine, 1986, Volume: 150, Issue:1

    Topics: Animals; Dynorphins; Endorphins; Glucose; Insulin; Insulin Secretion; Male; Morphine; Pancreas; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Somatostatin

1986
Effects of clonidine and propranolol on separation-induced distress in infant rhesus monkeys.
    Brain research, 1988, Aug-01, Volume: 470, Issue:2

    Topics: Animals; Anxiety, Separation; Clonidine; Exploratory Behavior; Female; Macaca mulatta; Male; Morphine; Motor Activity; Propranolol; Reference Values; Vocalization, Animal

1988
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone.
    Neuroendocrinology, 1986, Volume: 43, Issue:2

    Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics

1986
[Alpha- and beta-sympathomimetic effects on the electrically stimulated isolated guinea pig ileum].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:3

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Depression, Chemical; Electric Stimulation; Epinephrine; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naphazoline; Naphthalenes; Nasal Decongestants; Norepinephrine; Phentolamine; Propranolol; Sympathomimetics; Thiazines

1970
Neurohumoral control of blood coagulation. I. Effects of adrenergi drugs or ACTH administration and stress.
    Acta physiologica latino americana, 1971, Volume: 21, Issue:1

    Topics: Adrenalectomy; Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Blood Coagulation; Central Nervous System; Depression, Chemical; Epinephrine; Factor VIII; Hypophysectomy; Isoproterenol; Morphine; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Stimulation, Chemical; Stress, Physiological; Sympatholytics; Sympathomimetics; Vasopressins

1971
Effect of - and -adrenergic blocking agents and para-chlorophenylalanine on morphine- and caffeine-stimulated locomotor activity of mice.
    Psychopharmacologia, 1973, Volume: 28, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Caffeine; Drug Antagonism; Ethanolamines; Female; Fenclonine; Locomotion; Male; Mice; Morphine; Motor Activity; Nitrobenzenes; Phenethylamines; Phenoxybenzamine; Propranolol

1973
Comparative effects of sotalol and propranolol on myocardial contractility.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Chloride; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Extracorporeal Circulation; Heart; Heart Rate; Isoproterenol; Morphine; Propranolol; Reserpine; Sotalol

1973
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline

1973
Alpha adrenergic blocking agents: anti-nociceptive activity and enhancement of morphine-induced analgesia.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesia; Animals; Brain; Carbon Radioisotopes; Dopamine beta-Hydroxylase; Drug Synergism; Hot Temperature; Male; Morphine; Norepinephrine; Pentobarbital; Phenoxybenzamine; Phentolamine; Practolol; Propranolol; Rats; Reaction Time; Time Factors

1974
Effects of alpha-adrenergic blocking agents on narcotic-induced analgesia.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain Chemistry; Dopamine beta-Hydroxylase; Drug Interactions; Drug Synergism; Hot Temperature; Male; Morphine; Narcotics; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Reaction Time; Thiazoles; Thiourea; Time Factors

1974
Central actions of some beta-adrenoceptor blocking agents.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Body Temperature; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Ethanolamines; Ethers; Indenes; Isoproterenol; Mice; Morphine; Nicotine; Nitrobenzenes; Pentobarbital; Pentylenetetrazole; Phenethylamines; Practolol; Propanolamines; Propranolol; Rats; Reaction Time; Sotalol; Strychnine

1974
Effect of propranolol on morphine metabolism.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Carbon Dioxide; Carbon Radioisotopes; Depression, Chemical; Glucuronates; Heart Rate; Humans; Isoproterenol; Male; Morphine; Propranolol; Respiration; Time Factors

1974
Effect of mianserin, a potent anti-serotonin agent, on the isolated rat stomach fundus preparation.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium; Chlorpromazine; Cyproheptadine; Dextroamphetamine; Dibenzazepines; Dioxins; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methysergide; Morphine; Muscle Contraction; Phenoxybenzamine; Piperidines; Propranolol; Pyrazines; Rats; Receptors, Drug; Scopolamine; Serotonin; Serotonin Antagonists; Stomach; Tryptamines

1974
[Participation of monoaminergic mechanisms of the rat hypothalamus in conditioned avoidance reactions].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:4

    Topics: Aminobutyrates; Animals; Avoidance Learning; Depression, Chemical; Dihydroergotamine; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Methysergide; Morphine; Motor Activity; Muscle Tonus; Norepinephrine; Phentolamine; Propranolol; Rats; Reaction Time; Serotonin; Serotonin Antagonists; Stimulation, Chemical

1973
Analysis of the effects on body temperature of intracerebroventricular injection in anaesthetized dogs of gamma-aminobutyric acid.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Acetylcholine; Aminobutyrates; Animals; Body Temperature; Cerebral Ventricles; Dogs; Epinephrine; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Histamine; Injections; Isoproterenol; Lysergic Acid Diethylamide; Male; Morphine; Norepinephrine; Pentobarbital; Perfusion; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Pyrilamine; Reserpine; Salicylates; Scopolamine; Serotonin; Time Factors

1974
Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Calcium; Carbon Radioisotopes; Diaphragm; Drug Tolerance; Energy Metabolism; Epinephrine; Glucose; Glycogen; Glycogen Synthase; In Vitro Techniques; Male; Meperidine; Methadone; Morphinans; Morphine; Muscles; Narcotics; Phosphoglucomutase; Phosphorylases; Propranolol; Rats; Time Factors

1974
[Relations between adrenergic mechanisms and analgesic effects].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1969, Volume: 162, Issue:11

    Topics: Analgesics; Animals; Catecholamines; Drug Synergism; Epinephrine; Ergotamine; Isoproterenol; Mice; Morphine; Norepinephrine; Propranolol; Rats; Sympatholytics; Time Factors

1969
Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.
    FEBS letters, 1974, Dec-15, Volume: 49, Issue:2

    Topics: Animals; Cell Fusion; Cell Line; Clone Cells; Cyclic AMP; Fibroblasts; Glioma; Hybrid Cells; Kinetics; Mice; Morphine; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Propranolol; Prostaglandin Antagonists; Prostaglandins; Radioligand Assay; Rats

1974
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:10

    Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Heart Arrest; Heart Rate; Hexobarbital; Lidocaine; Male; Mice; Morphine; Nitrobenzenes; Propranolol; Quinidine; Seizures; Sleep; Urethane

1966
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine

1967
Pharmacological investigation of the mechanism of conditional salivation in dogs induced by atropine and morphine.
    European journal of pharmacology, 1969, Volume: 5, Issue:2

    Topics: Animals; Atropine; Conditioning, Classical; Dogs; Female; Guanethidine; Histamine H1 Antagonists; Male; Morphine; Phentolamine; Propranolol; Pyridines; Salivation; Xerostomia

1969
Prostaglandin e1 action on canine isolated tracheal muscle.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:8

    Topics: Acetylcholine; Animals; Bradykinin; Depression, Chemical; Dogs; Ergotamine; In Vitro Techniques; Isoproterenol; Methysergide; Morphine; Muscle, Smooth; Propranolol; Prostaglandins; Receptors, Drug; Serotonin Antagonists; Trachea

1969
An investigation into the bradycardic effects of ST 155 [2-(2,6-dichlorophenylamino)-2-imidazoline HCl] in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 169, Issue:1

    Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Chloralose; Depression, Chemical; Dogs; Epinephrine; Ethanolamines; Female; Guanethidine; Heart Rate; Imidazoles; Male; Morphine; Norepinephrine; Pentobarbital; Pentolinium Tartrate; Phenoxybenzamine; Piperazines; Propranolol; Time Factors; Vagotomy

1969
The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Analgesia; Animals; Ephedrine; Methyltyrosines; Mice; Morphine; Narcotic Antagonists; Neurotransmitter Agents; Pargyline; Physostigmine; Piperazines; Propranolol; Reserpine; Tail; Tetrabenazine; Tranylcypromine; Tremorine; Tyramine; Tyrosine

1970
Modification of morphine analgesia by drugs affecting adrenergic and tryptaminergic mechanisms.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:12

    Topics: Analgesia; Animals; Female; Hot Temperature; Male; Methyltyrosines; Methysergide; Mice; Morphine; Phentolamine; Phenylalanine; Propranolol; Reserpine; Serotonin; Spasm

1970
Analysis of the effects of beta-adrenergic blockade on patterns and parameters of the respiratory--heart rate response.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Dogs; Electrocardiography; Heart Rate; Morphine; Propranolol; Respiration; Sympathetic Nervous System

1971
Effect of drugs that modify 3',5'-AMP concentrations on morphine analgesia.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:1

    Topics: Analgesia; Animals; Cyclic AMP; Drug Synergism; Female; Fluorides; Imidazoles; Mice; Morphine; Propranolol; Sodium Chloride; Theophylline

1972
Role of central dopaminergic receptors in manic response of cats to morphine.
    Psychopharmacologia, 1972, Volume: 24, Issue:3

    Topics: Animals; Atropine; Bipolar Disorder; Cats; Central Nervous System; Chlorpromazine; Dopamine; Drug Antagonism; Female; Haloperidol; Histamine H1 Antagonists; Humans; Lysergic Acid Diethylamide; Male; Morphine; Phenoxybenzamine; Propranolol; Pyrroles; Receptors, Drug; Reserpine; Tetrabenazine

1972
The effect of dopamine on peripheral vasculature of the rat.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine

1972
Inhibitory effect of certain drugs on NADH dehydrogenase of mouse heart homogenates.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:1

    Topics: Animals; Chloral Hydrate; Cocaine; Cytochrome c Group; Cytochrome Reductases; Dextroamphetamine; Electron Transport Complex IV; Ephedrine; Fenfluramine; In Vitro Techniques; Mice; Morphine; Myocardium; NADH, NADPH Oxidoreductases; Oxidoreductases; Pentobarbital; Procainamide; Procaine; Propranolol; Propylamines

1973
The effect on some receptors of guinea pig trachea of a series of sympathomimetics amines.
    European journal of pharmacology, 1971, Volume: 16, Issue:2

    Topics: 1-Propanol; Adrenergic beta-Antagonists; Amines; Amino Alcohols; Amphetamine; Animals; Atropine; Biogenic Amines; Catecholamines; Ephedrine; Ethylamines; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Methamphetamine; Methylamines; Methysergide; Morphine; Norepinephrine; Phenethylamines; Phenols; Phentolamine; Propranolol; Propylamines; Serotonin; Serotonin Antagonists; Sympathomimetics; Trachea

1971
Some pharmacological properties of the combination of etorphine and acepromazine (Immobilon) and the morphine antagonist, diprenorphine, in the dog.
    Acta pharmacologica et toxicologica, 1974, Volume: 34, Issue:3

    Topics: Acepromazine; Animals; Atropine; Blood Pressure; Body Temperature; Depression, Chemical; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Electrocardiography; Female; Heart Rate; Male; Mice; Morphinans; Morphine; Neuroleptanalgesia; Propranolol; Respiration; Stimulation, Chemical; Time Factors

1974
Propranolol antagonism of morphine-influenced behavior.
    Brain research, 1974, Jan-11, Volume: 65, Issue:2

    Topics: Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Inhibition, Psychological; Male; Morphine; Propranolol; Rats; Rats, Inbred Strains

1974
Propranolol and morphine: a lethal interaction.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Animals; Drug Interactions; Female; Morphine; Propranolol; Rats; Stereoisomerism

1974
Effect of narcotics on enzymes of acetylcholine metabolism in cultured cells from embryonic chick brains.
    Neuropharmacology, 1974, Volume: 13, Issue:5

    Topics: Acetylcholine; Acetylcholinesterase; Acetyltransferases; Amino Acids; Animals; Brain; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Choline; Drug Tolerance; Leucine; Levorphanol; Morphine; Naloxone; Narcotics; Nerve Tissue Proteins; Neurons; Parasympathetic Nervous System; Propranolol; Stereoisomerism; Sympathetic Nervous System; Time Factors; Tritium

1974
Effect of acetylcholine on desensitization of isolated rat trachea to 5-hydroxytryptamine--a possible allosteric interaction between drug receptors.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Depression, Chemical; Histamine; In Vitro Techniques; Isoproterenol; Male; Morphine; Muscle Contraction; Muscle, Smooth; Phenylephrine; Propranolol; Rats; Receptors, Drug; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tachyphylaxis; Tetrodotoxin; Trachea; Tryptamines

1972
Central mechanisms of the hypertensive action of intraventricular bradykinin in the unanaesthetized rat.
    Neuropharmacology, 1974, Volume: 13, Issue:1

    Topics: Alkaloids; Amides; Animals; Atropine; Behavior, Animal; Benzyl Compounds; Blood Pressure; Bradykinin; Catechols; Catheterization; Cerebral Ventricles; Diphenhydramine; Eledoisin; Ethylenediamines; Fatty Acids, Unsaturated; Hexamethonium Compounds; Injections; Injections, Intra-Arterial; Kallidin; Lysergic Acid Diethylamide; Male; Methysergide; Morphine; Norepinephrine; Phentolamine; Propranolol; Pyridines; Rats; Stereotaxic Techniques; Time Factors

1974
EFfects of propranolol on the binding of ( 14 C)morphine to particulate fractions of mouse brain.
    Brain research, 1972, Dec-12, Volume: 47, Issue:2

    Topics: Animals; Brain; Carbon Isotopes; Dibenzylchlorethamine; Lidocaine; Mice; Morphine; Phenoxybenzamine; Pilocarpine; Propranolol; Subcellular Fractions

1972
[Hypermagnesemia and medullo-adrenal secretion].
    Annales de biologie animale, biochimie, biophysique, 1972, Volume: 12, Issue:3

    Topics: Adaptation, Physiological; Adrenal Medulla; Animals; Atropine; Blood Glucose; Carbachol; Cold Temperature; Drug Synergism; Epinephrine; Female; Hemorrhage; Hexamethonium Compounds; Histamine; Hypoxia; Insulin; Magnesium; Male; Morphine; Phentolamine; Pilocarpine; Propranolol; Rats; Reserpine

1972
The actions of 5-hydroxytryptamine on the urinary bladder and on vesical autonomic ganglia in the cat.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:1

    Topics: Animals; Atropine; Cats; Electric Stimulation; Female; Ganglia, Autonomic; Guanethidine; Hemicholinium 3; Hexamethonium Compounds; Male; Methysergide; Morphine; Muscle Contraction; Nicotine; Picrotoxin; Propranolol; Quaternary Ammonium Compounds; Receptors, Drug; Serotonin; Serotonin Antagonists; Urinary Bladder

1973
Myogenic peristalsis in isolated preparations of chicken oesophagus.
    British journal of pharmacology, 1973, Volume: 48, Issue:1

    Topics: Acetylcholine; Animals; Chickens; Cocaine; Esophagus; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Methysergide; Morphine; Mucous Membrane; Muscle Contraction; Nicotine; Norepinephrine; Papaverine; Phentolamine; Picrotoxin; Pressure; Propranolol; Rectum; Scopolamine; Stimulation, Chemical; Strychnine; Tetrodotoxin; Tubocurarine; Vagus Nerve

1973
Pharmacological analysis of the effects of metoclopramide on the guinea-pig ileum in vitro.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 204, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Methysergide; Metoclopramide; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Procaine; Propranolol; Scopolamine; Serotonin; Tetrodotoxin; Time Factors

1973
The action of hordenine on the superior cervical ganglion of the cat.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cats; Cocaine; Dimethylamines; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epinephrine; Female; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Male; Methadone; Morphine; Muscle Contraction; Nicotine; Nictitating Membrane; Phenethylamines; Propranolol; Receptors, Adrenergic; Receptors, Cholinergic; Time Factors

1973
Effect of morphine on the SA node of the dog.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 206, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Depression, Chemical; Dogs; Electric Stimulation; Heart Atria; Heart Rate; In Vitro Techniques; Morphine; Propranolol; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve

1973
Duration of the ectopic hypersensitivity to adrenergic stimulation after coronary occlusion in the canine heart.
    Journal of electrocardiology, 1974, Volume: 7, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Barbiturates; Coronary Disease; Dogs; Electric Stimulation; Electrocardiography; Electrodes, Implanted; Epinephrine; Heart; Injections, Intravenous; Isoproterenol; Morphine; Practolol; Propranolol; Stimulation, Chemical; Sympathetic Nervous System; Sympathomimetics; Time Factors

1974
Influence of adrenergic blockers and antilipemic agents on pharmacodynamic actions of morphine in carbon tetrachloride-treated rats.
    Toxicology and applied pharmacology, 1974, Volume: 27, Issue:3

    Topics: Animals; Carbon Tetrachloride; Dibenzylchlorethamine; Drug Synergism; Ergotamine; Female; Hemodynamics; Heparin; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Morphine; Nicotinic Acids; Propranolol; Rats; Reaction Time; Sympatholytics; Tolazoline

1974
Morphine physical dependence in the dog.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dogs; Dose-Response Relationship, Drug; Haloperidol; Hot Temperature; Humans; Morphinans; Morphine; Morphine Dependence; Naloxone; Propranolol; Pulse; Pupil; Reflex; Respiration; Skin; Substance Withdrawal Syndrome; Time Factors

1974
[Application of unanesthesia hypoxemia tests for experimental animals on screening method of angina pectoris therapeutics].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1968, Volume: 64, Issue:2

    Topics: Adenosine Triphosphate; Angina Pectoris; Animals; Atropine; Carbon Dioxide; Cardanolides; Dipyridamole; Male; Meprobamate; Methods; Morphine; Nitroglycerin; Noscapine; Oxygen; Papaverine; Propranolol; Rabbits; Rats; Technology, Pharmaceutical; Tolazoline; Vasodilator Agents

1968
[Conservative therapy of angina pectoris].
    Schweizerische medizinische Wochenschrift, 1970, May-16, Volume: 100, Issue:20

    Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides; Furans; Heart Failure; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Morphine; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Propranolol; Rest; Sympatholytics; Syncope; Vascular Headaches

1970
The pharmacology of the rat ureter in vivo.
    British journal of pharmacology, 1972, Volume: 44, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Epinephrine; Histamine; Isoproterenol; Male; Morphine; Norepinephrine; Propranolol; Rats; Serotonin; Ureter

1972
The effects of meperidine and morphine in rabbits pretreated with phenelzine.
    Toxicology and applied pharmacology, 1972, Volume: 22, Issue:2

    Topics: Animals; Body Temperature; Chlorpromazine; Depression, Chemical; Drug Antagonism; Drug Interactions; Female; Lysergic Acid Diethylamide; Male; Meperidine; Methysergide; Morphine; Motor Activity; Nalorphine; Phenelzine; Phenoxybenzamine; Propranolol; Rabbits; Stimulation, Chemical

1972
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
    American journal of veterinary research, 1972, Volume: 33, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal

1972
Effects of some drugs on electrical activity of the isolated colon of the cat.
    Gastroenterology, 1971, Volume: 61, Issue:4

    Topics: Animals; Atropa belladonna; Atropine; Cats; Colon; Electrodes; Electrophysiology; Female; Ganglionic Stimulants; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Methacholine Compounds; Methysergide; Morphine; Muscle, Smooth; Nicotine; Norepinephrine; Ouabain; Phenoxybenzamine; Physostigmine; Plants, Medicinal; Plants, Toxic; Propranolol; Serotonin

1971
[Pharmacological responses of the pyloric antrum strip of the rat stomach, with special reference to the mechanism of the contractions caused by serotonin and nicotine, relaxation of transmural stimulation and contraction and relaxation by tyramine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 46, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Barium; Bretylium Compounds; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Haloperidol; In Vitro Techniques; Methysergide; Morphine; Muscle Contraction; Nicotine; Phenoxybenzamine; Physostigmine; Procaine; Propranolol; Pylorus; Rats; Receptors, Drug; Scopolamine; Serotonin; Stimulation, Chemical; Tyramine

1971
Mode of action of partial agonists on the taenia caecum of the guinea pig and drug-receptor theory.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Atropine; Calcium; Choline; Colon; Dibenzylchlorethamine; Ephedrine; Guinea Pigs; Histamine; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Parasympathomimetics; Propranolol; Receptors, Drug; Strontium; Strychnine; Sympathomimetics; Tetrodotoxin

1969
[Nature of the central adreno- and serotonin-sensitive structures participating in the facilitating influence of bioamines on the respiratory reflex from the upper respiratory passages].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 70, Issue:10

    Topics: 5-Hydroxytryptophan; Ammonia; Animals; Cats; Dihydroxyphenylalanine; Ergotamine; Morphine; Norepinephrine; Phentolamine; Propranolol; Reflex; Respiration; Serotonin; Sympathetic Nervous System; Sympatholytics; Sympathomimetics

1970
[Analysis of adreno- and serotonin-sensitive structures of central links of the shaking and flexor reflexes in rabbits].
    Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 72, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Disulfiram; Ergot Alkaloids; Morphine; Parasympatholytics; Propranolol; Rabbits; Reaction Time; Reflex; Reserpine

1971
Effects of morphine on the level of the free fatty acids in the serum of rats.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:1

    Topics: Animals; Blood Glucose; Drug Tolerance; Ergotamine; Fatty Acids, Nonesterified; Glycerol; Male; Morphine; Nalorphine; Propranolol; Rats; Rats, Inbred Strains; Stimulation, Chemical

1971
[Characteristics of serotonin-reactive structures of the right atrium in rabbits].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 68, Issue:11

    Topics: Anesthetics, Local; Animals; Atrial Function; Creatinine; Epinephrine; Heart; Heart Atria; Indoles; Methods; Morphine; Muscle Contraction; Norepinephrine; Phentolamine; Procaine; Propranolol; Rabbits; Serotonin; Serotonin Antagonists

1969
The effects of bradykinin and eledoisin injected into the cerebral ventricles of conscious rats.
    European journal of pharmacology, 1970, Volume: 9, Issue:3

    Topics: Animals; Behavior, Animal; Blood Pressure; Bradykinin; Cerebral Ventricles; Consciousness; Eledoisin; Morphine; Phentolamine; Propranolol; Rats; Stimulation, Chemical

1970
[Analysis of the receptive structures participating in the behavior reactions of cats to catecholamines and serotonin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 70, Issue:9

    Topics: Animals; Catecholamines; Cats; Epinephrine; Isoproterenol; Lysergic Acid Diethylamide; Morphine; Motor Activity; Norepinephrine; Phentolamine; Propranolol; Sensory Receptor Cells; Serotonin; Sympathetic Nervous System

1970
Experimental evaluation of pentazocine: effect on myocardial contractility and peripheral vascular resistance.
    American heart journal, 1971, Volume: 81, Issue:3

    Topics: Animals; Aorta; Blood Flow Velocity; Blood Pressure; Catecholamines; Coronary Vessels; Dogs; Heart; Morphine; Myocardial Infarction; Oxygen; Pentazocine; Propranolol; Reserpine; Vascular Resistance

1971
[Adrenoceptor mechanisms in Oddi's sphincter].
    Nordisk medicin, 1971, Jul-29, Volume: 86, Issue:30

    Topics: Amino Alcohols; Ampulla of Vater; Cholecystokinin; Epinephrine; Gastrointestinal Motility; Humans; Isoproterenol; Morphine; Norepinephrine; Phenoxybenzamine; Propranolol

1971
Reversal of reserpine-induced hypothermia by pharmacological agents other than antidepressants.
    Nature, 1967, Nov-11, Volume: 216, Issue:5115

    Topics: Animals; Antidepressive Agents; Aspirin; Body Temperature; Chlorpromazine; Depression, Chemical; Desipramine; Male; Mice; Morphine; Phenoxybenzamine; Propranolol; Reserpine; Sympatholytics

1967
Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone).
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Bridged-Ring Compounds; Dextromoramide; Drug Synergism; Electric Stimulation; Furans; Guinea Pigs; Heroin; Ileum; In Vitro Techniques; Ketones; Levallorphan; Morphine; Muscle Contraction; Nalorphine; Narcotic Antagonists; Phenanthrenes; Phenoxybenzamine; Propranolol; Receptors, Drug; Tachyphylaxis

1968
Effects of beta-adrenergic blockade on the hemodynamic response to carotid sinus reflexes.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 175, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Carotid Sinus; Dogs; Heart Rate; Hemodynamics; Morphine; Propranolol; Sympatholytics; Vagotomy; Vascular Resistance

1968
Procaine-induced contraction in vein and its modification by drugs.
    Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Cats; Constriction; Epinephrine; Hexamethonium Compounds; Hydroxybutyrates; In Vitro Techniques; Lysergic Acid Diethylamide; Mesenteric Veins; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Ouabain; Phenoxybenzamine; Phentolamine; Phospholipases; Procaine; Propranolol; Rats; Serotonin

1969
Sinus arrhythmia in the dog.
    The American journal of physiology, 1966, Volume: 210, Issue:2

    Topics: Animals; Arrhythmia, Sinus; Chloralose; Dogs; Electrocardiography; Isoproterenol; Morphine; Phonocardiography; Propranolol; Succinylcholine; Sympatholytics; Vagus Nerve

1966
Effect of morphine on electrically-induced release of autonomic mediators in the rabbit sinoatrial node.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Heart Atria; Heart Conduction System; Hexamethonium Compounds; In Vitro Techniques; Morphine; Propranolol; Rabbits; Sinoatrial Node

1967
Skeletal muscle circulation during sufentanyl and morphine anesthesia in propranolol treated dogs.
    Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:1

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Blood Volume; Dogs; Dose-Response Relationship, Drug; Fentanyl; Hematocrit; Hydrogen-Ion Concentration; Morphine; Muscles; Propranolol; Regional Blood Flow; Sufentanil; Vascular Resistance

1981
The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs.
    Journal of neuroscience methods, 1980, Volume: 2, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Arousal; Behavior, Animal; Chlordiazepoxide; Corticosterone; Dose-Response Relationship, Drug; Drug Tolerance; Emotions; Ethanol; Interpersonal Relations; Meprobamate; Mice; Morphine; Phenobarbital; Propranolol; Rats; Social Environment

1980
High-dose analgesic anesthesia with morphine or sufentanil in propranolol-treated dogs.
    Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:5

    Topics: Analgesics, Opioid; Anesthesia; Animals; Carbon Dioxide; Dogs; Fentanyl; Hemodynamics; Hydrogen-Ion Concentration; Morphine; Oxygen Consumption; Propranolol; Sufentanil; Time Factors

1981
Effect of ACTH on opiate inhibition of oxytocin release.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Adrenocorticotropic Hormone; Animals; Cosyntropin; Dynorphins; Endorphins; Female; Lactation; Morphine; Oxytocin; Peptide Fragments; Pregnancy; Propranolol; Rats; Rats, Inbred Strains

1983
Should regional anesthesia and pharmacological agents such as beta blockers and opiates be utilized in modulating pain response?
    The Journal of trauma, 1984, Volume: 24, Issue:9 Suppl

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alfentanil; Analgesia; Analgesics; Anesthesia, Conduction; Animals; Burns; Cyclooxygenase Inhibitors; Fentanyl; Half-Life; Humans; Methadone; Models, Chemical; Morphine; Narcotics; Nerve Block; Pain; Pain Management; Propranolol

1984
[Inhibitory effect of morphine on guinea pig ileum contraction was modified by four monoamine blockers].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1983, Volume: 4, Issue:2

    Topics: Animals; Catecholamines; Cinanserin; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Phentolamine; Propranolol

1983
A mode of action of morphine on a quickly learned conditioned suppression in mice.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:3

    Topics: alpha-Methyltyrosine; Animals; Atropine; Biogenic Amines; Conditioning, Operant; Drug Interactions; Electric Stimulation; Fenclonine; Haloperidol; Male; Methyltyrosines; Mice; Morphine; Phenoxybenzamine; Pimozide; Propranolol; Reserpine

1984
Role of sympathetic system in morphine-induced mydriasis in rat.
    The American journal of physiology, 1981, Volume: 241, Issue:3

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Female; Guanethidine; Male; Morphine; Phentolamine; Propranolol; Pupil; Rats; Rats, Inbred Strains; Sympathectomy, Chemical

1981
Discriminative stimulus properties of d-amphetamine in pigeons.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4

    Topics: Amphetamine; Animals; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dronabinol; Lysergic Acid Diethylamide; Male; Morphine; Propranolol

1982
Peripheral circulation during sufentanyl and morphine anesthesia.
    Acta anaesthesiologica Scandinavica, 1980, Volume: 24, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Blood Circulation; Dogs; Fentanyl; Hematocrit; Hydrogen-Ion Concentration; Microcirculation; Morphine; Muscles; Propranolol; Sufentanil; Vascular Resistance

1980
Ventilatory transients during exercise: peripheral or central control?
    Pflugers Archiv : European journal of physiology, 1983, Volume: 396, Issue:4

    Topics: Animals; Central Nervous System; Dogs; Heart Rate; Mechanoreceptors; Morphine; Peripheral Nerves; Phenobarbital; Physical Exertion; Propranolol; Respiration

1983
Effects of morphine and pethidine on coronary vascular resistance, blood pressure, and myocardial infarction-induced cardiac arrhythmias.
    Japanese heart journal, 1983, Volume: 24, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Coronary Vessels; Dogs; Female; Male; Meperidine; Morphine; Myocardial Infarction; Perfusion; Propranolol; Vascular Resistance

1983
Bole of adrenals in morphine-induced hyperthermia in restrained rats.
    Life sciences, 1982, Apr-12, Volume: 30, Issue:15

    Topics: Adrenal Glands; Animals; Body Temperature; Female; Fever; Guanethidine; Male; Morphine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Scopolamine

1982
[Effect of danshensu on isolated swine coronary artery perfusion preparation (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1982, Volume: 17, Issue:3

    Topics: Animals; Coronary Vessels; In Vitro Techniques; Lactates; Morphine; Plants, Medicinal; Propranolol; Swine

1982
Interaction of beta-adrenergic agonists and antagonists with the stimulation of growth hormone release induced by clonidine or by morphine in the rat.
    The Journal of endocrinology, 1982, Volume: 94, Issue:3

    Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Growth Hormone; Isoproterenol; Male; Morphine; Propranolol; Rats; Rats, Inbred Strains

1982
A probable role for norepinephrine in feeding after hypothalamic injection of morphine.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:4

    Topics: Animals; Drug Interactions; Feeding Behavior; Hypothalamus; Injections; Male; Methysergide; Morphine; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains

1981
Central dopaminergic mechanism in morphine induced bradycardia.
    Indian journal of experimental biology, 1980, Volume: 18, Issue:5

    Topics: Animals; Atropine; Dopamine; Female; Haloperidol; Heart Rate; Male; Morphine; Phenoxybenzamine; Propranolol; Rabbits; Reserpine

1980
Serotonin receptors subserve only contraction in canine and rat pulmonary arteries and veins.
    Artery, 1980, Volume: 7, Issue:3

    Topics: Animals; Atropine; Dogs; Female; In Vitro Techniques; Male; Metiamide; Morphine; Phentolamine; Propranolol; Pulmonary Artery; Pulmonary Veins; Pyrilamine; Rats; Receptors, Serotonin; Serotonin; Vasoconstriction

1980
Experimental infarction studies.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Animals; Chlorpromazine; Dogs; Heart Rate; Ibuprofen; Morphine; Myocardial Infarction; Myocardium; Propranolol; Time Factors; Verapamil

1980
Neuronal mechanism of the inhibitory effect of calcitonin on N-methyl-D-aspartate-induced aversive behavior.
    European journal of pharmacology, 1995, Mar-06, Volume: 275, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Calcitonin; Cystamine; GABA Antagonists; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Phentolamine; Pindolol; Piperazines; Propranolol; Receptors, Neurotransmitter; Ritanserin; Serotonin Antagonists; Tropanes

1995
Effects of mu-, delta- and kappa-agonists on isolated right atria of the rat.
    Neuropeptides, 1994, Volume: 26, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Benzomorphans; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Propranolol; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1994
Comparison of the modifying effects of somatostatin and propranolol on morphine-induced changes in glucose, glucagon and insulin levels in fed rats.
    Life sciences, 1993, Volume: 52, Issue:2

    Topics: Animals; Blood Glucose; Drug Synergism; Food; Glucagon; Insulin; Morphine; Propranolol; Rats; Rats, Wistar; Somatostatin

1993
[Inhibitory effect of intraventricular administration of morphine on the hyperviscosity and elevation of blood pressure induced by stress in the rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1993, Volume: 45, Issue:3

    Topics: Animals; Blood Pressure; Blood Viscosity; Electroacupuncture; Injections, Intraventricular; Male; Morphine; Naloxone; Phentolamine; Propranolol; Rats; Rats, Wistar; Stress, Physiological

1993
Morphine tolerance and inhibition of oxytocin secretion by kappa-opioids acting on the rat neurohypophysis.
    The Journal of physiology, 1993, Volume: 469

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Biological Assay; Drug Tolerance; Electric Stimulation; Female; Injections, Intraventricular; Labor, Obstetric; Lactation; Morphine; Morphine Dependence; Naloxone; Oxytocin; Pituitary Gland, Posterior; Pregnancy; Propranolol; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Vasopressins

1993
Frequency dependence of vasoactive intestinal polypeptide release and vagally induced tachycardia in the canine heart.
    Journal of the autonomic nervous system, 1993, Volume: 43, Issue:2

    Topics: Animals; Dogs; Electric Stimulation; Electrocardiography; Female; Heart; Heart Rate; Male; Morphine; Myocardium; Parasympathetic Nervous System; Propranolol; Vagus Nerve; Vasoactive Intestinal Peptide

1993
Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Sep-01, Volume: 52, Issue:17

    Topics: Cardiotonic Agents; Drug Interactions; Drug Stability; Heparin; Humans; Lidocaine; Metoprolol; Morphine; Nitroglycerin; Plasminogen Activators; Propranolol; Tissue Plasminogen Activator

1995
Study of the mechanisms involved in behavioral changes induced by flunitrazepam in morphine withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 1995, Volume: 19, Issue:5

    Topics: Animals; Behavior, Animal; Dogs; Dose-Response Relationship, Drug; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Morphine; Prazosin; Propranolol; Substance Withdrawal Syndrome

1995
Effect of drugs on chemoreceptor responsiveness in fetal sheep.
    Pediatric research, 1995, Volume: 38, Issue:6

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Chemoreceptor Cells; Fetus; Heart Rate; Hypoxia; Ketamine; Morphine; Pentobarbital; Propranolol; Reproducibility of Results; Sheep

1995
Noninvasive quantification of regional myocardial metabolic rate of oxygen by 15O2 inhalation and positron emission tomography. Experimental validation.
    Circulation, 1996, Aug-15, Volume: 94, Issue:4

    Topics: Adenosine; Animals; Autoradiography; Blood Pressure; Carbon Dioxide; Carbon Radioisotopes; Dogs; Heart; Heart Rate; Hemodynamics; Inhalation; Isoproterenol; Morphine; Myocardium; Oxygen Consumption; Oxygen Radioisotopes; Propranolol; Regression Analysis; Reproducibility of Results; Tomography, Emission-Computed

1996
Antinociception and inhibition from the periaqueductal gray are mediated in part by spinal 5-hydroxytryptamine(1A) receptors.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Male; Microdialysis; Morphine; Nociceptors; Propranolol; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Serotonin; Spinal Cord; Time Factors

1996
Towards artificial antibodies prepared by molecular imprinting.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: Antibodies; Atrazine; Binding, Competitive; Corticosterone; Cross Reactions; Diazepam; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocortisone; Kinetics; Methylglucosides; Molecular Mimicry; Morphine; Polymers; Propranolol; Radioimmunoassay; Stereoisomerism; Theophylline; Yohimbine

1996
Potential role of the autonomic nervous system in the immunosuppressive effects of acute morphine administration.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: Animals; Atropine Derivatives; Autonomic Nervous System; Blood Pressure; Chlorisondamine; Heart Rate; Immunosuppressive Agents; Lymphocyte Activation; Male; Mice; Morphine; Nadolol; Neuropeptides; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley

1996
On the mechanism(s) of cholecystokinin (CCK): receptor stimulation attenuates morphine dependence in mice.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:3

    Topics: Adrenergic Antagonists; Animals; Atropine; Benzazepines; Ceruletide; Dopamine Antagonists; Male; Methysergide; Mice; Morphine; Morphine Dependence; Movement Disorders; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Cholecystokinin; Serotonin Antagonists; Sincalide; Substance Withdrawal Syndrome; Sulpiride

1997
Modulation of morphine-6-glucuronide penetration into the brain by P-glycoprotein.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cells, Cultured; Diffusion; Drug Resistance, Multiple; Endothelium, Vascular; Immunohistochemistry; Membrane Proteins; Morphine; Morphine Derivatives; Phosphoproteins; Propranolol; Sucrose; Swine; Vimentin; von Willebrand Factor; Zonula Occludens-1 Protein

1998
Oxidative injury reproduces age-related impairment of oxygen-dependent drug metabolism.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:5

    Topics: Anesthesia; Animals; Hydrogen Peroxide; Liver; Male; Morphine; Oxidative Stress; Oxygen Consumption; Perfusion; Propranolol; Rats; Rats, Wistar

1999
Norepinephrine modulates single hypothalamic arcuate neurons via alpha(1)and beta adrenergic receptors.
    Brain research, 2000, Jun-30, Volume: 869, Issue:1-2

    Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Cromakalim; Female; Glyburide; In Vitro Techniques; Locus Coeruleus; Magnesium; Male; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine

2000
The antinociceptive effect of FR140423 in mice: involvement of spinal alpha(2)-adrenoceptors.
    European journal of pharmacology, 2000, Jul-21, Volume: 400, Issue:2-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptors; Pain Measurement; Phentolamine; Prazosin; Propranolol; Pyrazoles; Receptors, Adrenergic, alpha-2; Spinal Cord; Sulfoxides; Yohimbine

2000
The importance of oxytocin mechanisms in the control of mouse parturition.
    Reproduction (Cambridge, England), 2002, Volume: 123, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Gene Expression; Genes, fos; Labor, Obstetric; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxytocin; Pregnancy; Propranolol; Receptors, Opioid, mu; Ritodrine; Stress, Physiological; Supraoptic Nucleus

2002
The sympathetic nervous system is involved in the inhibitory effect of morphine on the colon motility in rats.
    Autonomic neuroscience : basic & clinical, 2002, Sep-30, Volume: 100, Issue:1-2

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Colon; Gastrointestinal Motility; Male; Morphine; Narcotics; Neural Inhibition; Oxidopamine; Phentolamine; Propranolol; Rats; Rats, Wistar; Sympathectomy, Chemical; Sympathetic Nervous System; Time Factors

2002
Morphine-induced potentiation in the dentate gyrus of the hippocampus involves norepinephrine.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Dentate Gyrus; Evoked Potentials; Long-Term Potentiation; Male; Morphine; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley

2003
Involvement of noradrenergic system within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats.
    Psychopharmacology, 2003, Volume: 170, Issue:1

    Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Butoxamine; Conditioning, Operant; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Substance Withdrawal Syndrome; Timolol

2003
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine

2003
Morphine-induced macrophage apoptosis: oxidative stress and strategies for modulation.
    Journal of leukocyte biology, 2004, Volume: 75, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Antioxidants; Apoptosis; Calcium; Enzyme Activation; Enzyme Inhibitors; Epoetin Alfa; Erythropoietin; Heme Oxygenase (Decyclizing); Macrophages, Peritoneal; Mice; Morphine; NADPH Oxidases; Narcotics; Nitric Oxide; Onium Compounds; Oxidative Stress; Phospholipase D; Propranolol; Recombinant Proteins; Superoxides; Thapsigargin; Transforming Growth Factor beta

2004
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Gene Expression; Genes, fos; Heart Ventricles; Immunohistochemistry; Injections, Subcutaneous; Male; Morphine; Myocytes, Cardiac; Naloxone; Normetanephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Time Factors; Yohimbine

2004
Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier.
    Brain research, 2005, Dec-07, Volume: 1064, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Capillary Permeability; Cell Culture Techniques; Cell Line; Cells, Cultured; Daunorubicin; Endothelium, Vascular; Humans; Models, Biological; Morphine; Narcotics; Propranolol; Sucrose; Swine; Verapamil

2005
[Particular features of the impact of certain vegetotropic drugs on the excitability of cholinergic structures, contractile myocardial function and electromotive stomach activity].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2005, Issue:5

    Topics: Animals; Autonomic Nervous System; Bretylium Tosylate; Heart; Morphine; Motor Activity; Myocardial Contraction; Propranolol; Rabbits; Rats; Receptors, Cholinergic; Receptors, Serotonin, 5-HT3; Stomach; Sumatriptan

2005
Central but not peripheral beta-adrenergic antagonism blocks reconsolidation for a morphine place preference.
    Behavioural brain research, 2007, Aug-22, Volume: 182, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug Administration Routes; Male; Memory; Morphine; Nadolol; Narcotics; Propranolol; Rats; Rats, Long-Evans

2007
Morphine and propranolol co-administration impair consolidation of Y-maze spatial recognition memory.
    Brain research, 2008, Sep-16, Volume: 1230

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Memory; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Propranolol; Recognition, Psychology; Space Perception

2008
Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:10

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Propranolol; Rats; Rats, Sprague-Dawley; Reflex, Startle; Substance Withdrawal Syndrome; Time Factors

2009
Reconsolidation of a morphine place preference: impact of the strength and age of memory on disruption by propranolol and midazolam.
    Behavioural brain research, 2010, Dec-01, Volume: 213, Issue:2

    Topics: Amnesia; Animals; Choice Behavior; Conditioning, Psychological; Drug Synergism; Male; Memory; Midazolam; Morphine; Propranolol; Rats; Time Factors

2010
The effect of propranolol dose and novelty of the reactivation procedure on the reconsolidation of a morphine place preference.
    Behavioural brain research, 2011, Jan-01, Volume: 216, Issue:1

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Association Learning; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Morphine; Narcotics; Propranolol; Rats; Rats, Long-Evans; Reward

2011
[Effects of propranolol on acquisition and retrieval of morphine- induced conditioned place preference memories in ICR mice].
    Dong wu xue yan jiu = Zoological research, 2011, Volume: 32, Issue:6

    Topics: Animals; Conditioning, Psychological; Extinction, Psychological; Humans; Male; Memory; Mice; Mice, Inbred ICR; Morphine; Propranolol; Receptors, Adrenergic, beta; Substance-Related Disorders

2011
Differential effect of beta-adrenergic receptor antagonism in basolateral amygdala on reconsolidation of aversive and appetitive memories associated with morphine in rats.
    Addiction biology, 2014, Volume: 19, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Anisomycin; Appetitive Behavior; Avoidance Learning; Choice Behavior; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Memory; Microinjections; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Phentolamine; Propranolol; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Recurrence; Substance Withdrawal Syndrome

2014
Remembered for forgetting.
    Nature medicine, 2012, Apr-05, Volume: 18, Issue:4

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Emotions; Humans; Memory Disorders; Mental Recall; Morphine; Propranolol; Randomized Controlled Trials as Topic; Recovery of Function; Stress Disorders, Post-Traumatic

2012
Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:3

    Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Aminoacetonitrile; Animals; Catechol O-Methyltransferase; Corticosterone; Extracellular Signal-Regulated MAP Kinases; Heart; Heart Ventricles; HSP27 Heat-Shock Proteins; Hypothalamo-Hypophyseal System; Male; Morphine; Morphine Dependence; Naloxone; Norepinephrine; Phosphorylation; Pituitary-Adrenal System; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Substance Withdrawal Syndrome

2012
Interactive effects of morphine and scopolamine, MK-801, propanolol on spatial working memory in rhesus monkeys.
    Neuroscience letters, 2012, Aug-15, Volume: 523, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cholinergic Antagonists; Dizocilpine Maleate; Drug Interactions; Macaca mulatta; Male; Memory, Short-Term; Morphine; Propranolol; Receptors, Opioid, mu; Scopolamine; Single-Blind Method; Space Perception

2012
Interaction between morphine and noradrenergic system of basolateral amygdala on anxiety and memory in the elevated plus-maze test based on a test-retest paradigm.
    Archives of Iranian medicine, 2013, Volume: 16, Issue:5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amygdala; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Male; Maze Learning; Memory; Morphine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Opioid

2013
Differential effects of propranolol on conditioned hyperactivity and locomotor sensitization induced by morphine in rats.
    Scientific reports, 2014, Jan-21, Volume: 4

    Topics: Adrenergic Antagonists; Animals; Conditioning, Psychological; Humans; Hyperkinesis; Memory, Long-Term; Morphine; Motor Activity; Propranolol; Rats; Receptors, Adrenergic

2014
The interaction between morphine and propranolol in chemical and electrical seizure models of mice.
    Neurological research, 2016, Volume: 38, Issue:2

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Electroshock; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Propranolol; Seizures; Time Factors

2016