Page last updated: 2024-08-16

propranolol and mexiletine

propranolol has been researched along with mexiletine in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199025 (46.30)18.7374
1990's4 (7.41)18.2507
2000's12 (22.22)29.6817
2010's13 (24.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM1
Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA1
Shaw, TR1
Kidner, PH1
Fomina, IG; Iankin, VV1
Tanabe, T1
Ito, T; Kobayashi, A; Kobayashi, T; Ogawa, K; Watanabe, T; Yamazaki, N1
Abdalla, A; Mazur, NA1
Abdalla, A; Iavorskaia, NV; Mazur, NA; Sumarokov, AB1
Furuya, H; Goto, Y; Ide, M; Tagawa, R; Tanabe, T; Yoshikawa, H1
Morganroth, J; Nestico, PF2
Berman, ND; Loukides, JE1
Endou, K; Sato, T; Yamamoto, H1
Schwartz, PJ; Vanoli, E1
Schwartz, PJ; Vanoli, E; Zaza, A; Zuanetti, G1
Gang, ES; Hamer, A; Mandel, WJ; Oseran, DS; Peter, T; Rosenthal, ME1
Adinolfi, L; Bonaduce, D; Chiariello, M; Dote, I; Golia, B; Masullo, LA1
Kurbanov, RD; Mazur, NA1
Beck, OA; Hochrein, H; Pacholke, H1
Bhatia, ML; Kaul, U; Mohan, JC1
Rosen, MR; Wit, AL1
Cho, YW; Kuemmerle, HP; Singh, BN1
Flouvat, B1
DiMarco, JP; Garan, H; Ruskin, JN1
Perrenoud, JJ1
Johnston, A; Lewis, AM; Patel, L; Turner, P1
Bigger, JT; Giardina, EG; Heissenbuttel, RH; Leahey, EB1
McCall, JG; Simmons, W; Slater, SD1
Hisaoka, T; Kawai, S; Nakata, Y; Nakazato, Y; Ogura, S; Okada, R; Sumiyoshi, M; Yamaguchi, H1
Lin, CS; Tsai, YC; Wang, JN; Wu, JM; Yao, CT1
Chen, H; Xu, H; Yu, X1
Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C1
Bailey, A; DI Maria, M; Howley, LW; Schaffer, MS1
Cantu, F; Crotti, L; De Filippo, P; George, AL; Ikeda, T; Kishiki, K; Miyazaki, A; Pedrazzini, M; Schwartz, PJ; Shimizu, W; Wang, DW1
Aziz, PF; Pass, RH; Shah, MJ; Tanel, RE; Vetter, VL; Vogel, RL; Wieand, TS; Zelster, IJ1
Abdi, SH; Bajaj, HC; Khan, NU; Kureshy, RI; Roy, T; Sadhukhan, A1

Reviews

6 review(s) available for propranolol and mexiletine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
    Cardiology clinics, 1986, Volume: 4, Issue:2

    Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil

1986
Antiarrhythmic agents for chronic ventricular arrhythmias.
    Comprehensive therapy, 1987, Volume: 13, Issue:4

    Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide

1987
Electropharmacology of antiarrhythmic drugs.
    American heart journal, 1983, Volume: 106, Issue:4 Pt 2

    Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil

1983
[Utilization of anti-arrhythmic drugs].
    Schweizerische medizinische Wochenschrift, 1980, Jul-19, Volume: 110, Issue:29

    Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digitalis Glycosides; Dose-Response Relationship, Drug; Heart Conduction System; Humans; Kidney; Mexiletine; Myocardial Contraction; Propranolol; Ventricular Fibrillation; Verapamil; Wolff-Parkinson-White Syndrome

1980

Trials

5 trial(s) available for propranolol and mexiletine

ArticleYear
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
    Klinicheskaia meditsina, 1992, Volume: 70, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil

1992
Efficacy of combination therapy with mexiletine and a low dose of propranolol for premature ventricular arrhythmias.
    Japanese circulation journal, 1990, Volume: 54, Issue:12

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Drug Therapy, Combination; Electrocardiography; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propranolol

1990
[Comparative study of the effectiveness of allapinin in patients with frequent and stable extrasystole].
    Kardiologiia, 1988, Volume: 28, Issue:11

    Topics: Aconitine; Aconitum; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Placebos; Propranolol; Quinidine

1988
[Comparative effectiveness of ethmozine, mexitil, quinidine and obsidan in the treatment of ventricular rhythm disorders].
    Kardiologiia, 1981, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Humans; Mexiletine; Middle Aged; Moricizine; Morpholines; Phenothiazines; Placebos; Propranolol; Quinidine

1981
[Potentiation of an anti-arrhythmia action by the combined use of mexiletine and propranolol].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-02, Volume: 109, Issue:9

    Topics: Aged; Cardiac Complexes, Premature; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Mexiletine; Middle Aged; Propranolol; Propylamines; Time Factors

1984

Other Studies

43 other study(ies) available for propranolol and mexiletine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Design, synthesis and anticonvulsant-analgesic activity of new
    MedChemComm, 2017, Jan-01, Volume: 8, Issue:1

    Topics:

2017
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
    Drugs, 1978, Volume: 15, Issue:4

    Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil

1978
The effect of mexiletine on left ventricular ejection: a comparison with lignocaine and propranolol.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 1

    Topics: Heart; Heart Ventricles; Humans; Lidocaine; Mexiletine; Physical Exertion; Propranolol; Propylamines

1977
Prevention of ventricular arrhythmias after myocardial infarction.
    Journal of the Royal College of Physicians of London, 1977, Volume: 11, Issue:4

    Topics: Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Ventricular Fibrillation

1977
Combination antiarrhythmic treatment among class Ia, Ib, and II agents for ventricular arrhythmias.
    Cardiovascular drugs and therapy, 1991, Volume: 5 Suppl 4

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Disopyramide; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propranolol

1991
[Experience with the combined use of 1st- and 2d-group anti-arrhythmic preparations in patients with refractory arrhythmia].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:6

    Topics: Aconitine; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Propranolol

1988
Evaluation of antiarrhythmic drug efficacy using holter electrocardiographic technique.
    Japanese circulation journal, 1985, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Disease; Diltiazem; Disopyramide; Drug Evaluation; Electrocardiography; Female; Humans; Male; Mexiletine; Middle Aged; Monitoring, Physiologic; Propranolol

1985
The cellular electropharmacology of the simultaneous administration of propranolol and mexiletine: a class I and II antiarrhythmic drug combination.
    Journal of electrocardiology, 1987, Volume: 20, Issue:5

    Topics: Action Potentials; Animals; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Heart Conduction System; Male; Mexiletine; Propranolol; Purkinje Fibers

1987
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
    Japanese heart journal, 1987, Volume: 28, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil

1987
An experimental approach to the choice of antiarrhythmic therapy.
    European heart journal, 1986, Volume: 7 Suppl A

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil

1986
The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity.
    American heart journal, 1985, Volume: 109, Issue:5 Pt 1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Disease Models, Animal; Electrocardiography; Hemodynamics; Lidocaine; Mexiletine; Prazosin; Propranolol; Stellate Ganglion

1985
The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias.
    American heart journal, 1985, Volume: 110, Issue:5

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; Female; Heart Arrest; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Mitral Valve Prolapse; Procainamide; Propafenone; Propiophenones; Propranolol; Risk

1985
[Ventricular tachycardia].
    Minerva medica, 1985, Nov-17, Volume: 76, Issue:44

    Topics: Amiodarone; Aprindine; Digitalis Glycosides; Electrocardiography; Heart Aneurysm; Heart Ventricles; Humans; Mexiletine; Pacemaker, Artificial; Propranolol; Quinidine; Risk; Tachycardia; Tachycardia, Paroxysmal

1985
Acute effects of anti-arrhythmic drugs on cardiac pacing threshold.
    Acta cardiologica, 1984, Volume: 39, Issue:3

    Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrophysiology; Female; Heart; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Propranolol; Verapamil

1984
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:5

    Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Propranolol; Tocainide

1981
[Determination of plasma concentrations of anti-arrhythmia agents].
    Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74 Spec No

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biological Availability; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine

1981
Quinidine for ventricular arrhythmias: value of electrophysiologic testing.
    The American journal of cardiology, 1983, Jan-01, Volume: 51, Issue:1

    Topics: Aged; Drug Therapy, Combination; Electric Stimulation; Electrocardiography; Female; Humans; Male; Mexiletine; Middle Aged; Propranolol; Quinidine; Tachycardia; Ventricular Fibrillation

1983
Mexiletine in human blood and breast milk.
    Postgraduate medical journal, 1981, Volume: 57, Issue:671

    Topics: Adult; Female; Humans; Mexiletine; Milk, Human; Postpartum Period; Pregnancy; Propranolol; Propylamines; Time Factors

1981
Combined mexiletine and propranolol treatment of refractory ventricular tachycardia.
    British medical journal, 1980, Aug-02, Volume: 281, Issue:6236

    Topics: Aged; Drug Therapy, Combination; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propranolol; Propylamines; Tachycardia

1980
Mexiletine for supraventricular tachycardia.
    British medical journal, 1980, Oct-18, Volume: 281, Issue:6247

    Topics: Drug Synergism; Drug Therapy, Combination; Humans; Mexiletine; Propranolol; Propylamines; Tachycardia

1980
A case of idiopathic ventricular fibrillation with incomplete right bundle branch block and persistent ST segment elevation.
    Japanese heart journal, 1993, Volume: 34, Issue:5

    Topics: Adult; Bundle-Branch Block; Cardiac Catheterization; Electrocardiography; Humans; Male; Mexiletine; Propranolol; Stress, Psychological; Ventricular Fibrillation

1993
Congenital long QT syndrome with functionally impaired atrioventricular conduction: successful treatment by mexiletine and propranolol.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2002, Volume: 101, Issue:4

    Topics: Drug Therapy, Combination; Heart Block; Humans; Infant, Newborn; Long QT Syndrome; Male; Mexiletine; Propranolol

2002
Enantiomeric separation of basic drugs with partially filled serum albumin as chiral selector in capillary electrophoresis.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2004, Volume: 20, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Chlorpheniramine; Electrophoresis, Capillary; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Mexiletine; Propranolol; Serum Albumin; Stereoisomerism; Swine

2004
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Mar-01, Volume: 847, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil

2007
Neonatal long QT syndrome type 3 predicted by positive lidocaine challenge.
    Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:3

    Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Female; Humans; Infant, Newborn; Lidocaine; Long QT Syndrome; Mexiletine; Propranolol

2010
Malignant perinatal variant of long-QT syndrome caused by a profoundly dysfunctional cardiac sodium channel.
    Circulation. Arrhythmia and electrophysiology, 2008, Volume: 1, Issue:5

    Topics: Action Potentials; Anti-Arrhythmia Agents; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Genetic Predisposition to Disease; Gestational Age; Humans; Infant, Newborn; Kinetics; Long QT Syndrome; Male; Mexiletine; Muscle Proteins; Mutation, Missense; Myocardium; NAV1.5 Voltage-Gated Sodium Channel; Phenotype; Propranolol; Recombinant Proteins; Severity of Illness Index; Sodium; Sodium Channel Blockers; Sodium Channels; Treatment Outcome

2008
Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrioventricular Block; Child; Child, Preschool; Cohort Studies; Defibrillators, Implantable; Female; Flecainide; Genotype; Humans; Infant; Infant, Newborn; Long QT Syndrome; Male; Mexiletine; Multivariate Analysis; Prognosis; Propanolamines; Propranolol; Retrospective Studies; Risk Assessment; Risk Factors; Torsades de Pointes; Treatment Outcome

2010
Asymmetric hydrolytic kinetic resolution with recyclable macrocyclic Co(III)-salen complexes: a practical strategy in the preparation of (R)-mexiletine and (S)-propranolol.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Apr-23, Volume: 18, Issue:17

    Topics: Catalysis; Cobalt; Kinetics; Mexiletine; Molecular Structure; Organometallic Compounds; Propranolol; Stereoisomerism

2012