propranolol has been researched along with metoprolol in 870 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 482 (55.40) | 18.7374 |
| 1990's | 140 (16.09) | 18.2507 |
| 2000's | 129 (14.83) | 29.6817 |
| 2010's | 104 (11.95) | 24.3611 |
| 2020's | 15 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, JJ; Christy, ME; Denny, GH; Freedman, MB; Gross, DM; Habecker, CN; Lyle, PA; Ponticello, GS; Sweet, CS; Varga, SL | 1 |
| Binet, JL; Cavero, IG; Lefèvre-Borg, F; Manoury, PM; Rousseau, J | 1 |
| Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
| Baldwin, JJ; Denny, GH; Freedman, MB; Gross, DM; Hirschmann, R; Ponticello, GS; Sweet, CS | 1 |
| Gubernator, K; Kansy, M; Senner, F | 1 |
| Iakovidis, D; Jackman, GP; Louis, SN; Louis, WJ; Nero, TL | 1 |
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bleasby, K; Brown, CD; Dudley, AJ | 1 |
| Faller, B; Wohnsland, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Hwang, KK; Mandagere, AK; Thompson, TN | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Pajeva, IK; Wiese, M | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Baker, JG | 1 |
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Brockhoff, PB; Christensen, MS; Guldbrandt, M; Jensen, BF; Padkjaer, SB; Refsgaard, HH | 1 |
| Caron, G; Ermondi, G | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Chandrasena, G; Gavai, AV; Nayeem, A; Santone, K; Vaz, RJ | 1 |
| Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Duke, BJ; Jackman, GP; Louis, SN; Louis, WJ; Machida, CA; Nero, TL; Rezmann-Vitti, LA | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Akamatsu, M | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Thorling, CA; Zhang, Q | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Charlton, SJ; Dickson, CJ; Duca, JS; Fairhurst, RA; Hornak, V; McKay, DJ; Pearlstein, RA; Reilly, J; Sandham, DA; Shaw, D; Sykes, DA; Velez-Vega, C | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Barouch-Bentov, R; Brannan, JM; De Jonghe, S; Dye, JM; Einav, S; Herdewijn, P; O'Brien, CM; Prugar, LI; Pu, SY; Rozenski, J; Schor, S; Wouters, R | 1 |
| Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Besterman, EM; Comerford, MB | 1 |
| Levy, JV | 1 |
| Carlsson, E; Fellenius, E; Gautier, E; Lundgren, B; Malatray, J | 1 |
| Corrall, RJ; Davidson, NM; French, EB; Shaw, TR | 1 |
| Chubb, IW; Raine, AE | 1 |
| Boorsma, M; Meems, L; Zaagsma, J | 1 |
| Meier, J | 1 |
| Graham, RM; Nyberg, G; Stokes, GS | 1 |
| Gooren, L; Harms, HH; Hesse, C; Spoelstra, AJ; Verschoor, L | 1 |
| Losse, H; Samizadeh, A; Wessels, F | 1 |
| Erdmann, E; Krawietz, W; Pruchniewski, M; Weinsteiger, M | 1 |
| Ahlman, H; Dahlström, A; Kewenter, J; Larsson, I; Lundberg, JM; Pettersson, G | 1 |
| Lund-Johansen, P | 1 |
| Fredén, K; Kutti, J; Olsson, LB; Vilén, L | 1 |
| Kiechel, JR; Meier, J | 1 |
| Bennett, T; Gardiner, SM | 1 |
| Conolly, ME | 1 |
| Thulesius, O | 1 |
| Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S | 1 |
| Anderton, RC; Frith, PA; Hargreave, FE; Kumana, CR; Newhouse, MT; Ruffin, RE | 1 |
| Dunstan, R; Jackson, DM | 1 |
| Aberg, G; Adler, G; Wikberg, J | 1 |
| Christensen, NJ; Lanng Nielsen, J; Lederballe Pedersen, O; Mikkelsen, E | 1 |
| Carlsson, E; Herrmann, I; Lundgren, B | 1 |
| Eliasson, K; Lins, LE; Sundqvist, K | 1 |
| Littler, WA; Stallard, TJ; Watson, RD | 2 |
| Banks, DC; Patrick, JM; Pearson, SB | 2 |
| Aberg, G; Adler, G; Duker, G; Ek, B; Telemo, E | 1 |
| Fredén, K; Kutti, J; Lundborg, P; Olsson, LB; Vilén, L | 1 |
| Boden, G; Gugler, R; Höffgen, K; Krist, R; Raczinski, H | 1 |
| Calmette, C; Coevoet, B; Desplan, C; Fournier, A; Gherbrand, JD; Makdassi, R; Moukhtar, MS; Sebert, JL; Tolani, M | 1 |
| Caillens, G; Calmette, C; Coevoet, B; de Fremont, JF; Desplan, C; Fournier, A; Gueris, J; Moukhtar, MS | 1 |
| Carlsson, E; Fellenius, E; Lundborg, P; Svensson, L | 1 |
| Grimby, G; Smith, U | 1 |
| Blohmé, G; Lager, I; Smith, U | 1 |
| Kristensen, BO | 1 |
| Lederballe Pedersen, O; Mikkelsen, E | 1 |
| Amery, AK; Fagard, RH; Lijnen, PJ | 1 |
| Elmér, M | 1 |
| Florin-Christensen, A; Marshall, NJ; von Borcke, S | 1 |
| Larsson, S; Svedmyr, N | 1 |
| Kittel, E; Philippu, A | 1 |
| Snow, DH | 1 |
| Iisalo, E; Kanto, J; Lammintausta, R; Mäntylä, R; Syvälahti, E | 1 |
| Hoffmann, A; Meier, M | 1 |
| Malchoff, CD; Marinetti, GV | 1 |
| Björntorp, P; Fellenius, E; Smith, U; William-Olsson, T | 1 |
| De Boo, T; Fennis, JF; Houben, H; Lemmens, W; Thien, T; Van 't Laar, A; Van Herwaarden, CL | 1 |
| Clement, DL | 2 |
| Anderson, SD; Bye, PT; Hamor, GP; Nyberg, G; Perry, CP; Theobald, G | 1 |
| Bosman, AR; Goldberg, B; McKechnie, JK; Offermeier, J; Oosthuizen, OJ | 1 |
| Binkhorst, RA; Fennis, JF; van Herwaarden, CL; van t'Laar, A | 1 |
| Binkhorst, RA; Fennis, JF; van Herwaarden, CL; van't Laar, A | 2 |
| McGavin, CR; Williams, IP | 1 |
| Fennis, JF; van 'T Laar, A; van Herwaarden, CL | 1 |
| Barber, SG; Kendall, MJ; Poole, PH; Wright, AD | 1 |
| Sinclair, DJ | 1 |
| Clausen, N; Damsgaard, T; Mellemgaard, K | 1 |
| Bewsher, PD; How, J; Murchison, LE | 1 |
| Giese, J; Ibsen, H; Leth, A; McNair, A | 1 |
| Federman, J; Vlietstra, RE | 1 |
| Chowanetz, W; Gross, W; Müller, K | 1 |
| Ljung, O | 2 |
| Bielmann, P; Leduc, G | 1 |
| Bewsher, PD; Davidson, RJ; How, J | 1 |
| Boström, SL; Fryklund, J | 1 |
| Dunn, FG; Lawrie, TD; Lorimer, AR | 1 |
| Augello, M; De Ponti, C; Ferratini, M; Pirelli, S; Rovelli, F; Salvadé, P | 1 |
| Anderson, R | 1 |
| Guy, PS; Snow, DH; Summers, RJ | 1 |
| Davidson, C; Singleton, W; Taylor, SH; Thadani, U | 2 |
| Dietz, A; Dölle, H; Kircher, S; Walter, J | 1 |
| Iisalo, E; Kanto, J; Lammintausta, R; Syvälahti, E | 1 |
| Seth, SD; Sivam, SP | 1 |
| Hatano, Y; Hayashi, S; Miyazaki, M; Okunishi, H; Toda, N | 1 |
| Lager, I; Smith, U | 1 |
| McSorley, PD; Warren, DJ | 1 |
| Brunner, H; Gelzer, J; Stepanek, J | 1 |
| Greding, H; Isbary, J; König, E; Nechwatal, W | 1 |
| Tivenius, L | 1 |
| Frick, MH; Luurila, O | 1 |
| Borer, JS; Comerford, MB; Sowton, E | 1 |
| Danielson, K; Melander, A; Scherstén, B; Wåhlin, E | 1 |
| Frick, MH; Virtanen, K | 1 |
| Newman, RJ | 1 |
| Snow, DH; Summers, RJ | 1 |
| Bühler, FR; Burkart, F; Pfisterer, M; Schweizer, W | 1 |
| Aurell, M; Johnsson, G; Sannerstedt, R; Svedmyr, N; Werkö, L | 1 |
| Fitzgerald, JD; Smith, EK; Viol, GW | 1 |
| Irwin, M; Maisel, AS; Motulsky, H; Murray, DR; Rearden, CA; Ziegler, M | 1 |
| Wennmalm, A | 1 |
| Boucher, M; Chapuy, E; Duchêne-Marullaz, P | 1 |
| Auclair, M; Mazière, C; Mazière, JC | 1 |
| de Haan, A; Franssen, C; Thien, T; Wollersheim, H | 1 |
| Bousser, MG; Massiou, H | 1 |
| Branch, CA; Knuepfer, MM | 1 |
| Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L | 1 |
| Ghani, P; Lopatin, IuM; Mareev, VIu; Sinitsin, VE | 1 |
| Maev, IV; V'iuchnova, ES | 1 |
| Kulcsár, A; Kulcsár-Gergely, J | 1 |
| Bellini, AM; Minozzi, L; Quaglio, MP | 1 |
| Bhanumurthy, S; Muralidhar, K | 1 |
| Allen, B; Brodsky, M; Doria, R; Sada, M; Sato, D; Thomas, G | 1 |
| Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L | 1 |
| Feldt-Rasmussen, U; Hansen, JE; Hegedüs, L; Kayser, L; Perrild, H; Skovsted, L | 1 |
| Boucher, M; Gachon, P; Moins, N; Renoux, M | 1 |
| Mills, RG; Roberts, MS; Shen, JJ; Wanwimolruk, S | 1 |
| Godtrfedsen, J; Kelbaek, H | 1 |
| Amstislavskaja, TG; Naumenko, EV; Osadchuk, AV | 1 |
| Barber, R; Stickle, D | 2 |
| Agrawal, HR; Das, DK; Engelman, RM; Liu, XK | 1 |
| Bedi, GS | 1 |
| Luck, MR; Münker, M | 1 |
| Holzer, BC; Kostis, JB; Rosen, RC; Seltzer, LG; Taska, LS | 1 |
| Haunsø, S; Sejrsen, P; Svendsen, JH | 1 |
| Gupta, A; Lemming, D; Lennmarken, C; Lindqvist, J | 1 |
| Koch, G; Wessely, P; Wöber, C; Wöber-Bingöl, C | 1 |
| Bobrov, VA; Chervonopiskaia, EM; Delikatnaia, NV; Frolov, AI; Galichanskiĭ, IV; Mitchenko, EI | 1 |
| de Barros Neto, TL; de Barros, AL; Ferreira, NM; Freire, E; Russo, AK | 1 |
| Lithell, HO | 1 |
| Dumasia, MC; Houghton, E | 1 |
| Asselt, LM; Cleophas, TJ; Oudshoorn, NH; Quadir, SU | 1 |
| Richardson, SB; Twente, S | 1 |
| Grosgogeat, Y; Komajda, M; Lechat, P; Salloum, J | 1 |
| Dimenäs, E; Kerr, D; Macdonald, I | 1 |
| Adler, LA; Angrist, B; Rotrosen, J | 1 |
| Garrino, MG; Henquin, JC | 1 |
| Hughson, RL; Klein, CS; Kowalchuk, JM | 1 |
| Hughson, RL; Kowalchuk, JM | 1 |
| Bauer, K; Kaik, G; Rakusan, S | 1 |
| Chee, KY; Sachdev, P | 1 |
| Enquist, M; Hermansson, J | 1 |
| Inukai, T; Ishii, A; Iwashita, A; Kobayashi, I; Kobayashi, S; Kobayashi, T; Shimomura, Y; Yamaguchi, T; Yamaguchi, Y | 1 |
| Bailey, DG; Carruthers, SG | 1 |
| Diener, HC; Gerber, WD; Niederberger, U; Scholz, E | 1 |
| Wu, S | 1 |
| Flodgaard, H; Hedman, C; Winther, K | 1 |
| Doggrell, SA | 2 |
| Cleophas, TJ; Stapper, GJ | 1 |
| Bia, MJ; Castellino, P; DeFronzo, RA | 1 |
| Gross, CR; O'Connell, MB | 1 |
| Leach, CN; Mack, GW; Nadel, ER; Pescatello, LS | 1 |
| Belpaire, FM; Bogaert, MG; Chauvelot-Moachon, L; de Smet, F; Rosseel, MT; Vermeulen, AM; Vynckier, LJ | 1 |
| Ades, PA; Gibson, TC; Gunther, PG; Maddalena, J; Meyer, WL; Orfeo, T | 1 |
| Henriksson, R; Ostman, M; Reiz, S; Sundström, S | 1 |
| Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB | 1 |
| Winther, K | 1 |
| Mason, R; Walker, G; Winslow, E | 1 |
| Itoh, Y; Oishi, R; Saeki, K; Senoo, Y; Teramoto, S; Yoshitomi, I | 1 |
| Freyschuss, U; Hjemdahl, P; Juhlin-Dannfelt, A; Linde, B | 2 |
| Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR | 1 |
| Imai, S; Nagatomo, T; Tsuchihashi, H | 1 |
| Ciemniewski, Z; Giec, L; Grzegorzewski, B; Swiderska, E; Trusz-Gluza, M | 1 |
| Katsenovich, RA; Kostko, SZ | 1 |
| Hughson, RL | 1 |
| Akritopoulos, P; Petounis, AD | 1 |
| Adler, L; Angrist, B; Kim, A; Rotrosen, J | 1 |
| Acuña, D; Castillo, MA; García-Torres, L; Haro, JM; Vargas, F | 1 |
| Brune, G; Grotemeyer, KH; Husstedt, IW; Schlake, HP | 1 |
| Hansen, JM; Jørgensen, B; Kayser, L; Perrild, H; Poulsen, HE; Skovsted, L | 1 |
| Metelitsa, VI | 1 |
| From, RP; Mehta, MP; Pathak, D | 1 |
| Bille, A; Dichgans, J; Diener, HC; Gerber, WD; Jäck, A; Niederberger, U; Scholz, E | 1 |
| Fogh-Andersen, N; Jørgensen, B; Kayser, L; Mølholm Hansen, JE; Perrild, H | 1 |
| Katsenovich, RA; Kostko, SZ; Mukhitdinova, GN; Trigulova, RKh; Vazidova, MA | 1 |
| Belpaire, FM; Bogaert, MG; Chindavijak, B; de Smet, F; Fraeyman, N | 1 |
| Gorzalka, BB; Mendelson, SD | 1 |
| Bilińska, ZT; Ruth-Maurin, A | 1 |
| Anderson, GF; Dhabuwala, CB; Ramakrishna, CV | 1 |
| Chiou, GC; Liu, HK; McLaughlin, MA; Watanabe, K | 1 |
| McGourty, JC; Silas, JH; Solomon, SA | 1 |
| Nylander, E | 1 |
| Jackson, PR; Lewis, RV; Ramsay, LE | 2 |
| Fletcher, GF | 1 |
| Areskog, NH | 1 |
| Lennard, MS | 1 |
| Floras, JS; Hassan, MO; Jones, JV; Sleight, P | 3 |
| Coffman, JD; Rasmussen, HM | 1 |
| Chihara, K; Fujita, T; Kaji, H; Kita, T; Kodama, H; Minamitani, N | 1 |
| Davies, RO; Moncloa, F; Sromovsky, JA; Walker, JF | 1 |
| Kawecka-Jaszcz, K; Skoczeń, M | 1 |
| Fink, M; Lemmer, B; Ohm, T; Winkler, H | 1 |
| Lyrenäs, E | 1 |
| Cruickshank, JM; Neil-Dwyer, G | 1 |
| Betts, TA; Blake, A; Crowe, A; Harvey, P; Knight, R; Mortiboy, D | 1 |
| Alford, C; Betts, TA | 1 |
| Westerlund, A | 1 |
| Smith, RL | 1 |
| Lepäntalo, M | 1 |
| Brownlee, WC; Durrington, PN; Large, DM | 1 |
| Arendt, RM; Greenblatt, DJ; Mutschler, E; Ochs, HR; Schäfer-Korting, M | 1 |
| Hawksworth, GM; Petrie, JC; Rigby, JW; Scott, AK | 1 |
| Bendotti, C; Samanin, R; Villa, M | 1 |
| Cybulska, I; Niegowska, J; Sznajderman, M; Zawadzki, Z | 1 |
| Kopia, GA; Ruffolo, RR | 1 |
| Fishbein, L; Jackson, CD | 1 |
| Abrahamsson, H; Lyrenäs, E | 1 |
| Tattersfield, AE; Thomas, MS | 1 |
| Jenkins, RR; Thomas, DP | 1 |
| Halawa, B; Mazurek, W | 1 |
| Angerås, U; Hasselgren, PO; Oldfors, A | 1 |
| Epstein, M; Oster, JR | 1 |
| Antonaccio, MJ; DeForrest, JM; High, J; Sybertz, E | 1 |
| Beilin, LJ; deKlerk, N; Margetts, B; Rogers, P; Vandongen, R | 1 |
| Lennard, MS; Silas, JH; Tucker, GT; Woods, HF | 1 |
| Belpaire, FM; Bogaert, MG; Mugabo, P; Rosseel, MT | 1 |
| Bühring, KU; Leopold, G; Pabst, J; Simane, Z; Ungethüm, W; Wiemann, H | 1 |
| Bonin, M; Corvol, P; Housset, E; Mathieu, JF; Vayssairat, M | 1 |
| Bühring, KU; Garbe, A | 1 |
| Burris, JF; Goldstein, J; Plachetka, JR; Sirgo, MA; Sutton, JM; Zager, PG | 1 |
| Angerås, U; Hasselgren, PO; Jagenburg, R; Lindstedt, G | 1 |
| Maertens de Noordhout, A; Schoenen, J; Timsit, M; Timsit-Berthier, M | 1 |
| Tfelt-Hansen, P | 1 |
| Hedman, C; Winther, K | 1 |
| Chak, W; Chan, MK; Ho, PW; Lin, HJ; Pun, KK; Yeung, CK; Yeung, RT | 1 |
| Bevan, JA; McPherson, GA | 1 |
| Greenblatt, DJ; Labedzki, L; Neugebauer, G; Ochs, HR | 1 |
| Angerås, U; Hasselgren, PO | 1 |
| Houtia, NE; Islam, S; Mazière, C; Mazière, JC; Polonovski, J | 1 |
| Hallberg, H | 1 |
| Goldhill, DR; Hoaglin, DC; Martyn, JA | 1 |
| Ablad, B; Dahlöf, C; Kahan, T | 1 |
| Brismar, K; Mogensen, L; Wetterberg, L | 1 |
| Bernini, F; Cighetti, G; Corsini, A; Fumagalli, R; Galli, G; Soma, M | 1 |
| Hall, PE; Kendall, MJ; Smith, SR | 1 |
| Croughwell, N; de Bruijn, N; Knopes, K; Reves, JG | 1 |
| Bode, JC; Teltscher, U; Walker, S | 1 |
| Feldman, RL; Hill, JA; Pepine, CJ; Prida, XE | 1 |
| Eliasson, K; Hjemdahl, P; Hylander, B; Kahan, T | 2 |
| Schauer, I; Schauer, UJ | 1 |
| Algra, A; Pool, J; Roelandt, JR; Simoons, ML; Tijssen, JG | 1 |
| Arends, BG; Böhm, RO; Rahn, KH; van Baak, MA; van Hooff, ME | 1 |
| Norris, RJ | 1 |
| Brooks, B; Danielsen, U; Hansen, JE; Jørgensen, B; Kayser, L; Perrild, H | 1 |
| Altomare, GF; Gandossi, E; Pigatto, PD; Polenghi, MM | 1 |
| DeNatale, RW; Leach, SD; Stern, H; Tilson, MD; Toole, AL | 1 |
| Clifford Rose, F; Joseph, R; Schultz, LU; Steiner, TJ | 1 |
| Hoitsma, AJ; Huysmans, FT; Koene, RA; van Heusden, FH; Wetzels, JF | 1 |
| Jekelis, AW; Kostis, JB; Rosen, RC | 1 |
| Ades, PA; Gunther, PG; Handy, MA; LeWinter, MM; Meacham, CP | 1 |
| Kato, T; Nagamine, F; Nakasone, J; Noguchi, K; Sakanashi, M | 1 |
| Bloom, FE; Chouvet, GE; Siggins, GR; Staunton, DA; Svensson, TH | 1 |
| Viinikka, L; Ylikorkala, O | 1 |
| Trap-Jensen, J; Winther, K | 1 |
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| Behnke, B; Gebhardt, A; Naegele, H; Strohbeck, M | 1 |
| Caldwell, GW; Evangelisto, M; Masucci, JA; White, R | 1 |
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| Arima, Y; Hasegawa, C; Izawa, H; Kumazawa, T; Lee, XP; Sato, K; Umezawa, H | 1 |
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| Asadian, P; Crawford, DH; Fletcher, LM; Khlentzos, AM; Li, P; Liu, X; Roberts, MS; Robertson, TA; Thorling, CA; Zou, YH | 1 |
| Shimosawa, T; Shintani-Ishida, K; Tsushima, K; Ueyama, T; Unuma, K; Yahagi, N; Yoshida, K | 1 |
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| Arias, C; Brillas, E; Cabot, PL; Centellas, F; Garrido, JA; Isarain-Chávez, E; Rodríguez, RM | 1 |
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| Figueroa, JJ; Fischer, PR; Gehrking, JA; Iodice, V; Kimpinski, K; Low, PA; Opfer-Gehrking, TL; Sandroni, P; Singer, W; Sletten, DM | 1 |
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| Ackerman, MJ; Beckmann, BM; Blom, NA; Chockalingam, P; Clur, SA; Crotti, L; Fischer, M; Girardengo, G; Harris, KM; Hauer, RN; Johnson, JN; Kääb, S; Rordorf, R; Rydberg, A; Schwartz, PJ; Spazzolini, C; van den Heuvel, F; van der Heijden, JF; Wilde, AA | 1 |
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| Barceló, D; Kasprzyk-Hordern, B; López-Serna, R; Petrović, M | 1 |
| Fu, Z; Jin, R; Jin, Y; Peng, Z; Qian, H; Sun, L; Xin, L | 1 |
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| Dixit, S; Park, JH | 2 |
| Assendelft, WJ; Blom, JW; Smelt, AF; van Dijk, CE | 1 |
| Bratt, EL; Östman-Smith, I | 1 |
| Guo, Y; He, B; Shen, N; Wupuer, H; Zhang, Y; Zhou, Y | 1 |
| Guo, Y; He, B; Xu, M; Zhang, Y; Zhou, Y | 1 |
| Dai, W; Kloner, RA; Sachdeva, J | 1 |
| Białk-Bielińska, A; Caban, M; Kumirska, J; Maszkowska, J; Mioduszewska, K; Puckowski, A; Stepnowski, P; Stolte, S; Wagil, M; Łukaszewicz, P | 1 |
| Annaert, P; Augustijns, P; Stappaerts, J; Tack, J; Wuyts, B | 1 |
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| Amidon, GE; Amidon, GL; Takeuchi, S; Tsume, Y | 1 |
| Abu-Zeitone, A; McNitt, S; Moss, AJ; Peterson, DR; Polonsky, B | 1 |
| Barbato, E; Bartunek, J; Berza, CT; De Bruyne, B; Di Gioia, G; Di Serafino, L; Sarno, G; Trimarco, B; Vanderheyden, M; Wijns, W | 1 |
| Jia, Z; Li, W; Wang, R; Xie, H; Yin, Q; Zhang, J | 1 |
| Dekyndt, B; Neut, C; Siepmann, F; Siepmann, J; Verin, J | 1 |
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| Chen, G; Chen, J; Huang, X; Liu, W; Lu, M; Yan, Z; Zhang, L | 1 |
| Giebułtowicz, J; Nałęcz-Jawecki, G; Sikorska, K; Stankiewicz, A; Stefański, M; Wroczyński, P | 1 |
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| Chen, H; Chi, J; Fu, Z; Lin, X; Liu, F; Sun, L; Wang, S; Zhu, Q | 1 |
| Arvidsson, T; Hedeland, M; Jasper, JT; Pettersson, CE; Sedlak, DL; Svan, A | 1 |
| Denkaew, T; Mangmool, S; Nishida, M; Parichatikanond, W; Phosri, S; Pinthong, D; Shimauchi, T | 1 |
| Al Dakhoul, S; Alabed, S; Bdaiwi, Y; Frobel-Mercier, AK; Sabouni, A | 1 |
| Li, Q; Shen, Y; Tan, X; Yang, J; Yang, Q | 1 |
| Alwera, S; Bhushan, R | 1 |
| Baranowska, I; Buszewski, B; Gadzała-Kopciuch, R; Kochańska, K; Konieczka, P; Kościelniak, P; Magiera, S; Namieśnik, J; Polkowska-Motrenko, H; Rutkowska, M; Samczyński, Z; Woźniakiewicz, A | 1 |
| Baron, MG; Hetheridge, MJ; Jackson, SK; Jha, AN; Mintram, KS; Moody, AJ; Owen, SF; Purcell, WM | 1 |
| Ahmed, AR; Bodmeier, R; Dashevskiy, A; Irfan, M; Kolter, K | 1 |
| Chen, W; Duan, L; Lee, MS; Ng, A; Nguyen, J; Shen, AY; Spencer, HT | 1 |
| Andrén, PE; Goodwin, RJA; Hayes, MA; Hilgendorf, C; Nilsson, A; Peric, A; Strimfors, M | 1 |
| Jiang, X; Sun, N; Xi, Y; Zhang, Y | 1 |
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| Brubaker, S; Koyfman, A; Long, B | 1 |
| Chatzidou, S; Georgiopoulos, G; Kontogiannis, C; Kosmopoulos, M; Papadopoulou, E; Rokas, S; Tsilimigras, DI; Vasilopoulos, G | 1 |
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| Casali, KR; Dartora, DR; Dias, LD; Eibel, B; Irigoyen, MC; Kalil, RAK; Kristochek, M; Lehnen, AM; Markoski, MM; Peres, TR | 1 |
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| Addison, D; Alam, M; Jneid, H; Kayani, W; Lakkis, N; Misra, A; Pham, D; Resar, J | 1 |
| Chen, W; Duan, L; Lee, MS; Ng, A; Spencer, HT | 1 |
| Alder, AC; Sun, H; Xu, J; Zhang, Y | 1 |
| Chatzidou, S; Georgiopoulos, G; Kontogiannis, C | 1 |
| Du, Y; Feng, Z; Huang, Z; Sun, X; Zhao, S | 1 |
| Blaabjerg, M; Christensen, K; Deuschl, G; Höglinger, GU; Hopfner, F; Kuhlenbäumer, G; Pottegård, A; Rösler, TW; Wod, M | 1 |
| Chen, C; Ding, W; Du, Y; Ma, X; Sun, X; Tao, Y | 1 |
| Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B | 1 |
| Al Dakhoul, S; Alabed, S; Bdaiwi, Y; Sabouni, A | 1 |
| Feng, X; Yao, S; Yohannes, A | 1 |
| Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H | 1 |
| Assadi, M; Dehdar, F; Esmaeeli, A; Keshavarz, Z; Seyedabadi, M | 1 |
| Asmar, S; Bible, L; Castanon, L; Chehab, M; Ditillo, M; Douglas, M; Joseph, B; Khurrum, M; Tang, A | 1 |
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| He, Y; Lu, Y; Ruan, Y; Sun, H; Xu, J; Zhang, Y; Zhu, H | 1 |
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| Caputi, M; Cerasoli, G; Cerretani, E; Corradini, E; Falco, A; Frati, C; Gherli, A; Gnetti, L; Graiani, G; Lagrasta, C; Lorusso, B; Madeddu, D; Nogara, A; Pilato, FP; Quaini, F; Roti, G | 1 |
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53 review(s) available for propranolol and metoprolol
| Article | Year |
|---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Comparative pharmacokinetics of beta-blockers].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol | 1978 |
[Beta-blockers and migraine].
Topics: Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Dilatation, Pathologic; Evoked Potentials, Visual; Humans; Metoprolol; Migraine Disorders; Nadolol; Platelet Aggregation; Propranolol; Receptors, Serotonin; Timolol | 1992 |
New-onset ventricular tachycardia during pregnancy.
Topics: Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Humans; Metoprolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol; Syncope; Tachycardia | 1992 |
Termination of paroxysmal supraventricular tachycardia with a nasogastric tube--a case report.
Topics: Adult; Humans; Intubation, Gastrointestinal; Male; Metoprolol; Propranolol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Vagus Nerve | 1991 |
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies | 1991 |
[Beta-blockers in the treatment of heart failure].
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Heart Failure; Humans; Metoprolol; Propranolol; Vasodilator Agents | 1990 |
[Adrenergic beta receptor blockaders in congestive heart failure: potential mechanisms of their action].
Topics: Cardiomyopathy, Dilated; Heart Ventricles; Humans; Metoprolol; Propranolol; Receptors, Adrenergic, beta | 1988 |
Oxidation phenotype and the metabolism and action of beta-blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Drug Interactions; Ethanolamines; Humans; Hypertension; Kinetics; Metoprolol; Oxidation-Reduction; Phenotype; Propranolol; Timolol | 1985 |
Enalapril in hypertension and congestive heart failure. Overall review of efficacy and safety.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Enalapril; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propranolol | 1985 |
[Beta-blockaders in the treatment of hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Oxprenolol; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol | 1985 |
Importance of receptor regulation in the pathophysiology and therapy of congestive heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Dogs; Guinea Pigs; Heart Failure; Heart Rate; Heart Ventricles; Humans; Isoproterenol; Metoprolol; Myocardial Contraction; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Glucagon; Receptors, Histamine H2 | 1986 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol | 1986 |
Beta blockers and renal function: a reappraisal.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Urea Nitrogen; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Heart; Humans; Hypertension; Kidney; Labetalol; Metoprolol; Nadolol; Propanolamines; Propranolol; Renal Circulation; Renin; Sympathomimetics; Vascular Resistance | 1985 |
Advances in the medical management of renovascular hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propanolamines; Propranolol; Renal Artery Obstruction; Renin-Angiotensin System; Saralasin; Timolol | 1984 |
beta-Adrenoceptor antagonists: new drugs and new indications.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Glaucoma; Humans; Hypertension; Kinetics; Metoprolol; Migraine Disorders; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1981 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Muscle fatigue and beta-blockers--a review.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Atenolol; Dogs; Dose-Response Relationship, Drug; Energy Metabolism; Fatigue; Fatty Acids, Nonesterified; Hemodynamics; Humans; Lactates; Metoprolol; Muscles; Perception; Physical Exertion; Pindolol; Propranolol; Rats; Tissue Distribution | 1983 |
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Drug Synergism; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose Tolerance Test; Glycerol; Glycogen; Humans; Hypertension; Hypoglycemia; Insulin; Lactates; Lactic Acid; Metoprolol; Oxprenolol; Propranolol | 1983 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
Comparative review of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Atenolol; Humans; Hypertension; Metoprolol; Migraine Disorders; Myocardial Infarction; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Humans; Metoprolol; Myocardial Infarction; Myocardium; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Timolol | 1984 |
The role of beta-adrenergic receptor antagonists in the prevention of sudden cardiac death.
Topics: Action Potentials; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiac Complexes, Premature; Coronary Disease; Drug Therapy, Combination; Humans; Metoprolol; Myocardial Infarction; Propranolol; Recurrence; Time Factors; Timolol | 1984 |
Effects of the adrenergic transmitter on epicardial coronary arteries.
Topics: Animals; Coronary Vessels; Electric Stimulation; Humans; Imidazoles; Metoprolol; Models, Cardiovascular; Neuromuscular Junction; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Propranolol; Tyramine | 1984 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil | 1983 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Metoprolol; Minoxidil; Nitroprusside; Patient Compliance; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors | 1980 |
[Treatment with beta-blockers in patients with acute coronary syndrome].
Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Atenolol; Clinical Trials as Topic; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Practice Guidelines as Topic; Propranolol; Syndrome | 1998 |
Beta-blocker therapy in heart failure: pathophysiology and clinical results.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Exercise; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Quality of Life; Stroke Volume; Time Factors; Vasodilator Agents; Xamoterol | 1999 |
Thyrotoxicosis, unstable angina and normal coronary angiogram.
Topics: Angina, Unstable; Anti-Arrhythmia Agents; Chest Pain; Combined Modality Therapy; Coronary Angiography; Drug Therapy, Combination; Female; Humans; Metoprolol; Middle Aged; Myocardial Ischemia; Propranolol; Thyroidectomy; Thyrotoxicosis; Thyroxine | 1999 |
Beta-blockers, angiotensin-converting enzyme inhibitors, and calcium antagonists in treatment of elderly patients with acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Humans; Metoprolol; Myocardial Infarction; Practice Guidelines as Topic; Propranolol; Treatment Outcome | 2000 |
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Flunarizine; GABA Agents; Headache; Humans; Ibuprofen; Metoprolol; Migraine Disorders; Practice Guidelines as Topic; Propranolol; Relaxation Therapy; Serotonin Receptor Agonists; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents | 2002 |
Should beta-blockers be used for the treatment of pediatric patients with chronic heart failure?
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Treatment Outcome | 2002 |
[Enantiomer separation by capillary electrochromatography].
Topics: Adrenergic beta-Antagonists; Chlorthalidone; Chromatography, High Pressure Liquid; Diuretics; Electrophoresis, Capillary; Metoprolol; Propranolol; Stereoisomerism | 2000 |
Beta-blockers and diabetes: the bad guys come good.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bisoprolol; Coronary Disease; Diabetes Mellitus, Type 2; Humans; Hypertension; Metoprolol; Myocardial Infarction; Prognosis; Propranolol | 2002 |
Is there still a role for treatment with beta-adrenoceptor antagonists in post-myocardial infarction patients with well-preserved left ventricular systolic function?
Topics: Adrenergic Antagonists; Angioplasty, Balloon, Coronary; Endothelium, Vascular; Humans; Metoprolol; Myocardial Infarction; Propranolol; Thrombolytic Therapy; Timolol; Ventricular Function, Left | 2008 |
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vascular Diseases; Pindolol; Propranolol; Randomized Controlled Trials as Topic | 2008 |
[Beta blockers in migraine prophylaxis].
Topics: Adrenergic beta-Antagonists; Drug Administration Schedule; Humans; Metoprolol; Migraine Disorders; Nadolol; Premedication; Propranolol | 2009 |
Beta-adrenergic blocking agents and dental vasoconstrictors.
Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions; Epinephrine; Humans; Hypertension; Metoprolol; Nordefrin; Propranolol; Vasoconstrictor Agents | 2010 |
β-blockers as endocrine disruptors: the potential effects of human β-blockers on aquatic organisms.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Endocrine Disruptors; Fishes; Gluconeogenesis; Glucose; Glycogenolysis; Insulin; Insulin Secretion; Lipolysis; Metoprolol; Molecular Structure; Mollusca; Muscle Contraction; Nadolol; Propranolol; Species Specificity; Water Pollutants, Chemical | 2011 |
[Effect of liver cirrhosis on pharmacokinetics and pharmacodynamics of drugs].
Topics: Analgesics; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertensive Agents; Hepatic Insufficiency; Humans; Lidocaine; Liver; Liver Cirrhosis; Metoprolol; Propranolol; Risk; Verapamil | 2013 |
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vascular Diseases; Pindolol; Propranolol; Randomized Controlled Trials as Topic; Regional Blood Flow; Walking | 2013 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic | 2016 |
Comparative efficacy of β-blockers on mortality and cardiovascular outcomes in patients with hypertension: a systematic review and network meta-analysis.
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Atenolol; Coronary Disease; Humans; Hydrophobic and Hydrophilic Interactions; Hypertension; Incidence; Metoprolol; Network Meta-Analysis; Oxprenolol; Propranolol; Stroke; Treatment Outcome | 2017 |
Alternative Treatment Options for Atrioventricular-Nodal-Reentry Tachycardia: An Emergency Medicine Review.
Topics: Adenosine; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Calcium Channel Blockers; Diltiazem; Electric Countershock; Electrocardiography; Emergency Medicine; Emergency Service, Hospital; Female; Humans; Male; Metoprolol; Propanolamines; Propranolol; Review Literature as Topic; Tachycardia, Atrioventricular Nodal Reentry; Vagus Nerve Stimulation; Verapamil | 2018 |
Hints on Diagnosing and Treating Headache.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Antihypertensive Agents; Headache; Humans; Metoprolol; Migraine Disorders; Propranolol; Research Design; Tension-Type Headache; Trigeminal Autonomic Cephalalgias | 2018 |
Outcomes of beta blocker use in cocaine-associated chest pain: a meta-analysis.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Carvedilol; Cocaine; Humans; Metoprolol; Propanolamines; Propranolol | 2018 |
Beta-blockers for congestive heart failure in children.
Topics: Adolescent; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Child; Child, Preschool; Heart Failure; Heart Transplantation; Humans; Infant; Infant, Newborn; Metoprolol; Propanolamines; Propranolol; Randomized Controlled Trials as Topic; Stroke Volume | 2020 |
Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Comorbidity; Heart Failure; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 2022 |
226 trial(s) available for propranolol and metoprolol
| Article | Year |
|---|---|
An eighteen months' study of the clinical response to metoprolol, a selective beta1-receptor blocking agent, in patients with angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Exercise Test; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Practolol; Propanolamines; Propranolol | 1976 |
The effect of mental arithmetic in normotensive and hypertensive subjects, and its modification by beta-adrenergic receptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hypertension; Male; Mental Processes; Metoprolol; Middle Aged; Pilot Projects; Propranolol; Time Factors | 1977 |
Metoprolol (Lopressor).
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol | 1978 |
Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Airway Resistance; Asthma; Double-Blind Method; Drug Interactions; Female; Forced Expiratory Volume; Histamine; Humans; Male; Metoprolol; Middle Aged; Organ Specificity; Propranolol; Pulse; Timolol | 1979 |
Abrupt withdrawal of beta-blocking agents in patients with arterial hypertension. Effect on blood pressure, heart rate and plasma catecholamines and prolactin.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Catecholamines; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Prolactin; Propranolol; Substance Withdrawal Syndrome; Sympathetic Nervous System; Time Factors | 1979 |
The effect of beta-adrenoceptor blockade on factors affecting exercise tolerance in normal man.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Gases; Hemodynamics; Humans; Male; Metoprolol; Oxygen Consumption; Physical Endurance; Physical Exertion; Propranolol; Respiration | 1979 |
Beta-adrenoceptor blocking drugs at maximum beta-blockade in relation to dose and plasma concentration.
Topics: Adrenergic beta-Antagonists; Adult; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Pindolol; Propranolol | 1979 |
beta-Adrenoceptor blockers, plasma-potassium, and exercise.
Topics: Clinical Trials as Topic; Humans; Hyperkalemia; Metoprolol; Physical Exertion; Placebos; Potassium; Propanolamines; Propranolol; Research Design; Rest | 1978 |
Beta-blockade and muscle function.
Topics: Adult; Clinical Trials as Topic; Exercise Test; Female; Humans; Male; Metoprolol; Muscle Contraction; Physical Exertion; Placebos; Propanolamines; Propranolol; Research Design | 1978 |
Effect of cardioselective and non-selective beta-blockade on the hypoglycaemic response in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; Blood Pressure; Bradycardia; Clinical Trials as Topic; Diabetes Mellitus; Diastole; Fatty Acids; Female; Humans; Hyperglycemia; Hypoglycemia; Injections, Intravenous; Insulin; Male; Metoprolol; Middle Aged; Placebos; Propanolamines; Propranolol; Pulse; Research Design | 1979 |
Selective and non-selective beta-blockade in renin release.
Topics: Administration, Oral; Adult; Blood Pressure; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Placebos; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Renin | 1977 |
Differences in metabolic responses to beta-adrenergic stimulation after propranolol or metoprolol administration.
Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Glycerol; Hemodynamics; Humans; Insulin; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sodium Chloride; Terbutaline | 1979 |
Effect of selective and non-selective beta-adrenoreceptor blockade on calf blood flow in hypertensive patients.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Leg; Metoprolol; Propanolamines; Propranolol | 1978 |
South African multicentre study of metoprolol and propranolol in essential hypertension.
Topics: Clinical Trials as Topic; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1977 |
Effects of adrenaline during treatment with propranolol and metoprolol.
Topics: Blood Pressure; Clinical Trials as Topic; Epinephrine; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol | 1977 |
Haemodynamic effects of adrenaline during treatment of hypertensive patients with propranolol and metoprolol.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Epinephrine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Placebos; Propanolamines; Propranolol; Time Factors | 1977 |
The effects of oral propranolol and metoprolol on lung function and exercise performance in chronic airways obstruction.
Topics: Administration, Oral; Aged; Airway Obstruction; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Propranolol; Random Allocation; Respiratory Function Tests | 1978 |
Effects of beta 1-selective and non-selective beta-blockade on blood pressure, plasma renin activity and plasma aldosterone in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Renin | 1979 |
Beta-adrenoceptor-blocking drugs and blood sugar control in diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1979 |
Comparison of effects of propranolol and metoprolol on airways obstruction in chronic bronchitis.
Topics: Airway Obstruction; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory Volume; Humans; Isoproterenol; Metoprolol; Middle Aged; Propanolamines; Propranolol; Random Allocation; Vital Capacity | 1979 |
Effects of propranolol and metoprolol on haemodynamic and respiratory indices and on perceived exertion during exercise in hypertensive patients.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Propranolol; Respiration | 1979 |
Antihypertensive effect of a non-selective (propranolol) and a cardioselective (metoprolol) beta-adrenoceptor blocking agent at rest and during exercise.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Humans; Hypertension; Metoprolol; Patient Compliance; Physical Exertion; Propanolamines; Propranolol; Pulse; Rest | 1979 |
Comparison of propranolol and metoprolol in the management of hyperthyroidism.
Topics: Adult; Calcium; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperthyroidism; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Time Factors | 1979 |
[Effects of propranolol and metoprolol on beta-adrenergic metabolic responses (author's transl)].
Topics: Adult; Blood Glucose; Blood Pressure; Female; Glycerol; Heart Rate; Humans; Male; Metaproterenol; Metoprolol; Potassium; Propanolamines; Propranolol | 1979 |
Effects of metoprolol and propranolol on lipid metabolism.
Topics: Cholesterol; Double-Blind Method; Humans; Hyperlipidemias; Lipid Metabolism; Metoprolol; Propanolamines; Propranolol; Triglycerides | 1979 |
Objective measurement of performance during acute stress in patients with essential hypertension: assessment of the effects of propranolol and metoprolol.
Topics: Adult; Automobile Driving; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Propanolamines; Propranolol; Stress, Psychological | 1979 |
[Effects of metoprolol acute administration on effort tolerance in patients affected by stable effort angina. Comparison with placebo and propranolol (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Physical Exertion; Placebos; Propanolamines; Propranolol | 1979 |
Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propanolamines; Propranolol | 1979 |
Cardioselective (metoprolol) and non-selective (propranolol) beta-blockade and glucose homeostasis.
Topics: Adult; Blood Glucose; Blood Pressure; Growth Hormone; Heart Rate; Homeostasis; Humans; Insulin; Male; Metoprolol; Physical Exertion; Propanolamines; Propranolol; Time Factors | 1977 |
The effects of propranolol and metoprolol on exercise responses in normal man [proceedings].
Topics: Electrocardiography; Humans; Metoprolol; Oxygen Consumption; Physical Exertion; Propanolamines; Propranolol; Respiratory Function Tests | 1978 |
Effects of propranolol and metoprolol on the peripheral circulation.
Topics: Blood Flow Velocity; Blood Pressure; Depression, Chemical; Humans; Hypertension; Male; Metoprolol; Muscles; Physical Exertion; Propanolamines; Propranolol; Skin; Skin Temperature | 1978 |
[Hemodynamic changes in patients with arterial hypertension after beta-receptor blockade with propranolol and metoprolol (author's transl)].
Topics: Cardiac Catheterization; Heart Rate; Hemodynamics; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Stroke Volume | 1978 |
Effects of muliple doses of metoprolol and propranolol on ventilatory function in patients with chronic obstructive lung disease.
Topics: Adult; Aged; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Female; Forced Expiratory Volume; Heart Rate; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Placebos; Propanolamines; Propranolol; Respiration; Respiratory Therapy; Tablets; Vital Capacity | 1976 |
Double-blind titrated-dose comparison of metoprolol and propranolol in the treatment of angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1976 |
Assessment of metoprolol, a cardioselective beta-blocking agent, during chronic therapy in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Physical Exertion; Placebos; Propanolamines; Propranolol; Time Factors | 1976 |
Comparison of the antilipolytic effect of metoprolol, acebutolol, and propranolol in man.
Topics: Acebutolol; Adult; Fatty Acids, Nonesterified; Humans; Insulin; Lipid Metabolism; Male; Metoprolol; Propanolamines; Propranolol | 1977 |
[Hemodynamic changes under metoprolol compared to propranolol in hypertensive patients].
Topics: Adult; Heart Rate; Humans; Hypertension; Metoprolol; Middle Aged; Propanolamines; Propranolol; Renin; Vascular Resistance | 1976 |
Comparison of metoprolol and propranolol in modification of haemodynamic and renin-aldosterone responses to tilting in humans.
Topics: Adult; Aldosterone; Blood Pressure; Depression, Chemical; Heart; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Posture; Propanolamines; Propranolol; Renin | 1976 |
Formation of prostacyclin during administration of beta 1-selective and non-selective beta-adrenergic antagonists in healthy humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic beta-Antagonists; Adult; Blood Pressure; Epoprostenol; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propranolol; Receptors, Adrenergic, beta | 1992 |
The influence of different beta-blocking drugs on the peripheral circulation in Raynaud's phenomenon and in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Raynaud Disease; Vascular Resistance | 1992 |
[Beta-blockers and migraine].
Topics: Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Dilatation, Pathologic; Evoked Potentials, Visual; Humans; Metoprolol; Migraine Disorders; Nadolol; Platelet Aggregation; Propranolol; Receptors, Serotonin; Timolol | 1992 |
[Potential possibilities of using adrenergic beta blockers in chronic heart failure].
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Prognosis; Propranolol | 1992 |
Attenuation of the cardiovascular responses to subcutaneous adrenaline in neurosurgical patients.
Topics: Adult; Blood Pressure; Brain; Drug Interactions; Epinephrine; Heart Rate; Humans; Injections, Subcutaneous; Metoprolol; Norepinephrine; Premedication; Propranolol | 1992 |
The thyroid function and size in healthy man during 3 weeks treatment with beta-adrenoceptor-antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Male; Metoprolol; Propranolol; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Beta blocker effects on heart rate during sleep: a placebo-controlled polysomnographic study with normotensive males.
Topics: Adrenergic beta-Antagonists; Atenolol; Cerebral Cortex; Double-Blind Method; Electrocardiography; Electroencephalography; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Monitoring, Physiologic; Pindolol; Propranolol; Sleep Stages | 1991 |
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies | 1991 |
A pressor effect of noncardioselective beta blockers in mildly hypertensive patients during surgery under anesthesia.
Topics: Aged; Anesthesia, General; Blood Pressure; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Preoperative Care; Propranolol; Stress, Physiological; Surgical Procedures, Operative | 1991 |
Beta-adrenoceptor blockade and CNS-related subjective symptoms: a randomized, double-blind, placebo-controlled comparison of metoprolol CR/ZOK, atenolol and propranolol LA in healthy subjects.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Central Nervous System; Delayed-Action Preparations; Double-Blind Method; Exercise; Female; Heart Rate; Humans; Male; Metoprolol; Propranolol; Randomized Controlled Trials as Topic; Tablets | 1990 |
Metoprolol versus propranolol.
Topics: Adult; Antipsychotic Agents; Dyskinesia, Drug-Induced; Humans; Metoprolol; Middle Aged; Neurologic Examination; Propranolol; Randomized Controlled Trials as Topic; Schizophrenia | 1990 |
Effect of beta-adrenergic blockade on VO2 kinetics during pseudorandom binary sequence exercise.
Topics: Adrenergic beta-Antagonists; Adult; Exercise; Humans; Kinetics; Male; Metoprolol; Models, Biological; Oxygen Consumption; Physical Exertion; Propranolol; Random Allocation | 1990 |
Pulmonary effects of long-term beta 2-blockade in healthy subjects: comparative study of metoprolol OROS.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Airway Resistance; Albuterol; Blood Pressure; Delayed-Action Preparations; Female; Heart Rate; Humans; Lung; Male; Metoprolol; Propranolol; Randomized Controlled Trials as Topic; Reference Values; Time Factors | 1990 |
Pharmacological characterization of tardive akathisia.
Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztropine; Brain; Bromocriptine; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Infusions, Intravenous; Male; Metoclopramide; Metoprolol; Physostigmine; Propranolol; Psychomotor Agitation; Schizophrenia, Paranoid | 1990 |
Interaction between oral verapamil and beta-blockers during submaximal exercise: relevance of ancillary properties.
Topics: Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Interactions; Exercise; Heart; Heart Rate; Humans; Male; Metoprolol; Pindolol; Propranolol; Random Allocation; Verapamil | 1991 |
Responders and non-responders to metoprolol, propranolol and nifedipine treatment in migraine prophylaxis: a dose-range study based on time-series analysis.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Nifedipine; Propranolol; Statistics as Topic; Time Factors | 1991 |
Platelet P1, P4-Di (adenosine-51) tetraphosphate (AP4A) in migraine patients before and during beta-adrenoceptor blockade.
Topics: Adenosine Triphosphate; Adult; Blood Platelets; Dinucleoside Phosphates; Female; Humans; Male; Metoprolol; Migraine Disorders; Propranolol; Receptors, Adrenergic, beta; Uridine Triphosphate | 1990 |
Adrenergic modulation of potassium metabolism in uremia.
Topics: Adult; Blood Pressure; Heart Rate; Humans; Metoprolol; Potassium; Propranolol; Uremia | 1990 |
The effect of single-dose phenylpropanolamine on blood pressure in patients with hypertension controlled by beta blockers.
Topics: Adult; Atenolol; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Humans; Hypertension; Male; Metoprolol; Middle Aged; Phenylpropanolamine; Propranolol; Random Allocation | 1990 |
Thermoregulation in mildly hypertensive men during beta-adrenergic blockade.
Topics: Analysis of Variance; Body Temperature Regulation; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Oxygen; Physical Exertion; Pindolol; Propranolol | 1990 |
Cardiac and skeletal muscle adaptations to training in systemic hypertension and effect of beta blockade (metoprolol or propranolol).
Topics: Adaptation, Physiological; Adult; Exercise Therapy; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Muscles; Oxygen Consumption; Propranolol | 1990 |
[Ways of individualizing use of anti-anginal preparations].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, Drug; Exercise Test; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Placebos; Propranolol; Vasodilator Agents | 1989 |
Ramp work tests with three different beta-blockers in normal human subjects.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Heart Rate; Humans; Lactates; Male; Metoprolol; Oxprenolol; Oxygen Consumption; Physical Exertion; Propranolol | 1989 |
Differential effect of continuous administration of beta-adrenoceptor antagonists on antipyrine and phenytoin clearance.
Topics: Adrenergic beta-Antagonists; Adult; Antipyrine; Atenolol; Humans; Male; Metoprolol; Phenytoin; Propranolol | 1989 |
Central effects of drugs used in migraine prophylaxis evaluated by visual evoked potentials.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Evoked Potentials, Visual; Female; Humans; Male; Metoprolol; Migraine Disorders; Nifedipine; Propranolol; Random Allocation; Reaction Time | 1989 |
Changes in serum phosphate during beta-blockade in healthy men are not due to changes in the renal handling of phosphate.
Topics: Adult; Atenolol; Clinical Trials as Topic; Humans; Kidney; Male; Metoprolol; Parathyroid Hormone; Phosphates; Propranolol; Random Allocation | 1989 |
[Comparative anti-angina effectiveness of metoprolol and propranolol].
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Clinical Trials as Topic; Exercise Test; Humans; Male; Metoprolol; Middle Aged; Physical Exertion; Placebos; Propranolol | 1989 |
Cardioselective and nonselective beta-adrenoceptor blocking drugs in hypertension: a comparison of their effect on blood pressure during mental and physical activity.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bicycling; Blood Pressure; Female; Humans; Hypertension; Isometric Contraction; Male; Mathematics; Metoprolol; Middle Aged; Pindolol; Propranolol; Random Allocation; Reaction Time; Thinking | 1985 |
Effects of beta-adrenoreceptor-blocking drugs in patients with Raynaud's phenomenon.
Topics: Adrenergic beta-Antagonists; Adult; Female; Fingers; Hemodynamics; Humans; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Regional Blood Flow | 1985 |
Beta-blockers and sleep: a controlled trial.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Female; Humans; Lipid Metabolism; Memory; Metoprolol; Pindolol; Propranolol; Random Allocation; Sleep; Sleep, REM; Solubility | 1985 |
Central nervous system side-effects with hydrophilic and lipophilic beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Central Nervous System; Double-Blind Method; Dreams; Female; Hallucinations; Heart Rate; Humans; Lipids; Male; Metoprolol; Middle Aged; Propranolol; Solubility; Water | 1985 |
Beta blockade and intermittent claudication.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; Hemodynamics; Humans; Hypertension; Intermittent Claudication; Labetalol; Leg; Male; Metoprolol; Middle Aged; Physical Exertion; Pindolol; Propranolol; Risk | 1985 |
Short-term effects of beta-adrenoceptor blocking drugs with and without cardioselectivity and intrinsic sympathomimetic activity on lipoprotein metabolism in hypertriglyceridaemic patients and in normal men.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cholesterol; Cholesterol, HDL; Female; Half-Life; Heart Rate; Humans; Hyperlipoproteinemias; Lipoproteins; Lipoproteins, VLDL; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Sotalol; Triglycerides | 1985 |
Beta adrenergic influence on oesophageal peristalsis in man.
Topics: Adrenergic beta-Agonists; Adult; Esophagus; Female; Humans; Male; Metoprolol; Middle Aged; Peristalsis; Practolol; Prenalterol; Pressure; Propranolol; Terbutaline | 1986 |
Comparison of beta-adrenoceptor selectivity of acebutolol and its metabolite diacetolol with metoprolol and propranolol in normal man.
Topics: Acebutolol; Adrenergic beta-Antagonists; Airway Resistance; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Metoprolol; Physical Exertion; Propranolol; Receptors, Adrenergic, beta | 1986 |
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol | 1986 |
Intravenous beta-blockade during acute myocardial infarction.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Humans; Injections, Intravenous; Metoprolol; Myocardial Infarction; Propranolol; Random Allocation; Ventricular Fibrillation | 1986 |
Blood pressure and catecholamines following exercise during selective beta-blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Catecholamines; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Norepinephrine; Physical Exertion; Propranolol; Time Factors | 1986 |
Pharmacodynamic profile of bisoprolol, a new beta 1-selective adrenoceptor antagonist.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Bisoprolol; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Propanolamines; Propranolol; Time Factors | 1986 |
[Hemodynamic study, under hot and cold conditions, of the digital artery in arterial hypertension and the effects of cardioselective and non-cardioselective beta blocker treatment].
Topics: Adrenergic beta-Agonists; Adult; Arteries; Cold Temperature; Female; Fingers; Hemodynamics; Hot Temperature; Humans; Hypertension; Male; Metoprolol; Middle Aged; Plethysmography; Propranolol | 1986 |
Comparative tolerability of labetalol versus propranolol, atenolol, pindolol, metoprolol, and nadolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propranolol | 1986 |
Efficacy of beta-blockers in migraine. A critical review.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Migraine Disorders; Nadolol; Propranolol; Racemases and Epimerases; Timolol | 1986 |
The effects of four beta-adrenoceptor antagonists during modest exercise on plasma ammonia and heart rate.
Topics: Adrenergic beta-Antagonists; Adult; Ammonia; Female; Heart Rate; Humans; Male; Metoprolol; Nadolol; Physical Exertion; Pindolol; Propranolol | 1987 |
[Beta-receptor blockaders in the prevention of hemorrhaging of esophageal varices?].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Drug Evaluation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoprolol; Nadolol; Placebos; Propranolol; Sclerosing Solutions | 1987 |
Comparison of selective (beta 1) and nonselective (beta 1 and beta 2) beta-adrenergic blockade on systemic and coronary hemodynamic findings in angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Coronary Circulation; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Metoprolol; Middle Aged; Propranolol; Random Allocation; Receptors, Adrenergic, beta | 1987 |
Responses to mental stress and physical provocations before and during long term treatment of hypertensive patients with beta-adrenoceptor blockers or hydrochlorothiazide.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cyclic AMP; Epinephrine; Female; Glycerol; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Norepinephrine; Posture; Propranolol; Stress, Psychological | 1987 |
Long-term antihypertensive therapy with beta-blockers: submaximal exercise capacity and metabolic effects during exercise.
Topics: Adrenergic beta-Antagonists; Adult; Electrocardiography; Energy Metabolism; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance; Pindolol; Propranolol; Random Allocation | 1987 |
Antihypertensive therapy with celiprolol: a new cardioselective beta blocker.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Celiprolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol | 1988 |
Three-week beta-adrenergic blockade does not impair or improve general intellectual function in young healthy males.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Attention; Clinical Trials as Topic; Humans; Intelligence; Learning; Male; Memory; Metoprolol; Propranolol; Random Allocation; Time Factors; Verbal Learning | 1988 |
Beta-blocker effects on sexual function in normal males.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Libido; Male; Metoprolol; Penile Erection; Pindolol; Propranolol; Random Allocation; Testosterone | 1988 |
Hypertension, exercise, and beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Combined Modality Therapy; Double-Blind Method; Exercise Therapy; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxygen Consumption; Physical Exertion; Propranolol; Random Allocation | 1988 |
Effects of three beta-blockers with different pharmacodynamic properties on platelet aggregation and platelet and plasma cyclic AMP.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Adult; Aged; Blood Platelets; Blood Pressure; Cyclic AMP; Female; Humans; Male; Metoprolol; Middle Aged; Pindolol; Platelet Aggregation; Propranolol; Pulse; Random Allocation | 1988 |
Effects of acute and chronic beta-adrenoceptor blockade on baroreflex sensitivity in humans.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Pindolol; Pressoreceptors; Propranolol; Reflex | 1988 |
Pharmacodynamic comparison of L-bunolol with propranolol, metoprolol, and placebo.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Echocardiography; Female; Heart; Heart Rate; Humans; Levobunolol; Male; Metoprolol; Propranolol | 1988 |
Effect of diltiazem on the pharmacokinetics of propranolol, metoprolol and atenolol.
Topics: Adult; Atenolol; Blood Pressure; Diltiazem; Half-Life; Heart Rate; Humans; Male; Metoprolol; Propranolol | 1989 |
Physical performance and serum potassium under chronic beta-blockade.
Topics: Adult; Double-Blind Method; Exercise Test; Humans; Kinetics; Male; Metoprolol; Muscles; Physical Exertion; Potassium; Propranolol; Receptors, Adrenergic, beta | 1985 |
Effect of metoprolol and propranolol on platelet aggregation and cAMP level in hypertensive patients.
Topics: Adenosine Diphosphate; Adult; Aged; Cyclic AMP; Epinephrine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Platelet Aggregation; Propranolol | 1986 |
Studies on the insulin-antagonistic effect of catecholamines in normal man. Evidence for the importance of beta 2-receptors.
Topics: Adult; Catecholamines; Fatty Acids, Nonesterified; Glucose; Heart Rate; Humans; Insulin; Insulin Antagonists; Male; Metoprolol; Propranolol; Receptors, Adrenergic, beta | 1986 |
The difference between non-selective and beta 1-selective beta-blockers in their effect on platelet function in migraine patients.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Blood Platelets; Cyclic AMP; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Platelet Aggregation; Propranolol | 1986 |
Cardiovascular and sympathoadrenal responses to mental stress: influence of beta-blockade.
Topics: Adult; Blood Pressure; Cardiac Output; Conflict, Psychological; Epinephrine; Heart Rate; Hemodynamics; Humans; Leg; Male; Metoprolol; Muscles; Norepinephrine; Propranolol; Reference Values; Regional Blood Flow; Stress, Psychological; Vascular Resistance | 1988 |
Ventricular dysrhythmias in middle-aged hypertensive men treated either with a diuretic agent or a beta-blocker.
Topics: Aged; Amiloride; Arrhythmias, Cardiac; Bendroflumethiazide; Clinical Trials as Topic; Drug Combinations; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Magnesium; Male; Metoprolol; Middle Aged; Potassium; Propranolol; Random Allocation | 1987 |
Metabolic response to exercise in dialysis patients.
Topics: Adult; Blood Glucose; Blood Pressure; Catecholamines; Fatty Acids, Nonesterified; Female; Glucose; Humans; Insulin; Kidney Failure, Chronic; Male; Metoprolol; Physical Exertion; Propranolol; Random Allocation; Renal Dialysis | 1987 |
Double-blind comparison of long acting propranolol and sustained release metoprolol in the treatment of angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Humans; Male; Metoprolol; Middle Aged; Propranolol; Random Allocation | 1987 |
Double-blind, randomized, cross-over clinical trial of metoprolol and propranolol in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Random Allocation | 1987 |
The effects of propranolol and metoprolol on skin blood flow in diabetic patients.
Topics: Adult; Aged; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Regional Blood Flow; Skin | 1987 |
Comparison of four beta-blockers as assessed by 24-hour ECG recording.
Topics: Acebutolol; Administration, Oral; Adult; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nadolol; Propanolamines; Propranolol; Random Allocation | 1986 |
The relative antihypertensive potency of propranolol, oxprenolol, atenolol, and metoprolol given once daily. A double-blind, crossover, placebo-controlled study in ambulatory patients.
Topics: Adult; Aged; Analysis of Variance; Atenolol; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Propranolol; Prospective Studies; Pulse | 1985 |
Comparison of five beta-adrenoreceptor antagonists with different ancillary properties during sustained twice daily therapy in angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Placebos; Practolol; Propanolamines; Propranolol; Time Factors | 1980 |
Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Heart Block; Heart Failure; Humans; Hypotension; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propranolol; Risk | 1980 |
Duration of action of beta blockers.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol | 1980 |
Cortisol, growth hormone and prolactin responses to insulin-induced hypoglycaemia in hyperthyroid patients before and during beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Female; Growth Hormone; Humans; Hydrocortisone; Hyperthyroidism; Hypoglycemia; Insulin; Male; Metoprolol; Middle Aged; Prolactin; Propranolol; Thyroxine; Triiodothyronine | 1980 |
Beta-adrenoceptor blockers and terbutaline in patients with chronic obstructive lung disease. Effects and interaction after oral administration.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Propranolol; Respiratory Function Tests; Terbutaline | 1980 |
Effect of beta-blockade on hormone release during hypoglycaemia in insulin-dependent diabetics.
Topics: Adrenergic beta-Antagonists; Adult; Alanine; Blood Glucose; Catecholamines; Diabetes Mellitus; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Metoprolol; Middle Aged; Propranolol | 1980 |
The effects of beta-adrenergic receptor blockade on the inhibition of gastric acid secretion, and the release of pancreatic polypeptide by antral distension in healthy subjects.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Female; Gastric Acid; Humans; Male; Metoprolol; Pancreas; Pentagastrin; Peptides; Propranolol; Pyloric Antrum; Random Allocation; Secretory Rate | 1980 |
Comparative pharmacodynamics and plasma levels of beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Pindolol; Propranolol | 1980 |
Blood pressure and pulse response to insulin-induced hypoglycemia during non-selective and selective beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Heart Rate; Humans; Hypoglycemia; Insulin; Male; Metoprolol; Propranolol; Pulse | 1981 |
Metoprolol in essential tremor.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Propanolamines; Propranolol; Random Allocation; Tremor | 1981 |
Intravenous beta-blockade in coronary heart disease: is cardioselectivity or intrinsic sympathomimetic activity hemodynamically useful?
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Random Allocation; Sympathetic Nervous System; Vascular Resistance | 1982 |
Speed of onset of pharmacodynamic activity of propranolol, practolol, oxprenolol and metoprolol after intravenous infection in man.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Heart Rate; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Time Factors | 1981 |
Response of the renin-angiotensin-aldosterone system to upright tilting and to intravenous frusemide: effect of prior metoprolol and propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Furosemide; Hemodynamics; Humans; Male; Metoprolol; Posture; Propanolamines; Propranolol; Renin-Angiotensin System | 1982 |
Influence of beta-blocking drugs on glucose metabolism in patients with non-insulin dependent diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glucagon; Glucose Tolerance Test; Humans; Hypertension; Insulin; Male; Metoprolol; Middle Aged; Propranolol | 1982 |
Inhibition of antipyrine metabolism by beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Antipyrine; Depression, Chemical; Humans; Kinetics; Male; Metoprolol; Propranolol; Terbutaline | 1981 |
Adrenergic mechanisms in control of plasma lipid concentrations.
Topics: Adrenergic beta-Antagonists; Atenolol; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Fatty Acids, Nonesterified; Female; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, VLDL; Male; Metoprolol; Oxprenolol; Propranolol; Random Allocation; Triglycerides | 1982 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Forum: beta-adrenoreceptor blockade after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Death, Sudden; Humans; Metoprolol; Myocardial Infarction; Propranolol; Recurrence; Timolol | 1982 |
Beta-adrenoceptor blockade and psychic stress in man. A comparison of the acute effects of labetalol, metoprolol, pindolol and propranolol on plasma levels of adrenaline and noradrenaline.
Topics: Adrenergic beta-Antagonists; Adult; Catecholamines; Epinephrine; Humans; Labetalol; Male; Metoprolol; Norepinephrine; Pindolol; Propranolol; Stress, Psychological | 1982 |
Beta-blocker therapy evaluated by radionuclide angiography: a study in chronic stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Cardiac Volume; Chronic Disease; Echocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propranolol; Radionuclide Imaging; Sotalol; Stroke Volume | 1982 |
Ineffectiveness of beta-adrenergic blockers on ventilatory response to carbon dioxide.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Carbon Dioxide; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Male; Metoprolol; Pindolol; Propranolol; Random Allocation; Respiration | 1982 |
beta-Blockers and myocardial infarction.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Diuretics; Humans; Hypertension; Metoprolol; Myocardial Infarction; Propranolol; Recurrence; Time Factors; Timolol | 1982 |
Labetalol, beta blockers, and acute deterioration of chronic airway obstruction.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Ethanolamines; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Lung Volume Measurements; Metoprolol; Middle Aged; Propranolol | 1982 |
Postinfarction therapy with beta blockers: who should be treated?
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Heart; Humans; Metoprolol; Myocardial Infarction; Propranolol; Random Allocation; Timolol | 1982 |
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol | 1982 |
Effects of cold exposure on blood pressure, heart rate and forearm blood flow in normotensives during selective and non-selective beta-adrenoceptor blockade.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cold Temperature; Female; Forearm; Heart Rate; Humans; Male; Metoprolol; Propranolol; Regional Blood Flow | 1982 |
Effect of the centrally acting agent clonidine on circulating catecholamines at rest and during exercise. Comparison with the effects of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Physical Exertion; Propranolol; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1983 |
Effect of long-term beta-adrenergic-blockade on calf blood flow in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aged; Ankle; Arm; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Leg; Male; Metoprolol; Middle Aged; Propranolol; Regional Blood Flow; Vascular Resistance | 1983 |
Beta-adrenergic blocking agents after myocardial infarction: an undocumented need in patients at lowest risk.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Propranolol; Research Design; Risk; Time Factors; Timolol | 1983 |
Effects of beta-adrenoceptor blocking drugs on human sigmoid colonic motility.
Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Colon, Sigmoid; Double-Blind Method; Female; Gastrointestinal Motility; Heart Rate; Humans; Male; Metoprolol; Pressure; Propranolol; Random Allocation | 1983 |
Chronic beta blockade therapy in patients after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol | 1983 |
[Use of adrenergic beta blockaders after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Propranolol; Timolol | 1983 |
[Beta receptor blockers and calcium antagonists in coronary disease. Differential therapeutic aspects].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxygen Consumption; Placebos; Prognosis; Propranolol; Timolol | 1983 |
[Improved prognosis using beta blockers after myocardial infarct?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Prognosis; Propranolol; Sotalol; Timolol | 1984 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
Propranolol vs metoprolol vs labetalol: a comparative study in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Isometric Contraction; Labetalol; Male; Metoprolol; Middle Aged; Peak Expiratory Flow Rate; Propranolol | 1984 |
Prophylactic use of beta-adrenergic blockade in survivors of myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Death, Sudden; Humans; Metoprolol; Myocardial Infarction; Propranolol; Recurrence; Timolol | 1984 |
Diazepam/beta-adrenoceptor antagonist interactions.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Diazepam; Drug Interactions; Emotions; Humans; In Vitro Techniques; Kinetics; Male; Metoprolol; Microsomes, Liver; Nordazepam; Propranolol; Psychomotor Performance; Rats; Rats, Inbred Strains; Reaction Time; Visual Acuity | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
Single-agent and combination therapy of essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Renin-Angiotensin System | 1984 |
Assessment of beta-adrenoceptor selectivity of a new beta-adrenoceptor antagonist, bisoprolol, in man.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Bronchi; Dose-Response Relationship, Drug; Heart Rate; Humans; Metoprolol; Physical Exertion; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1984 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Humans; Metoprolol; Myocardial Infarction; Myocardium; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Timolol | 1984 |
Influence of cardioselectivity and respiratory disease on pulmonary responsiveness to beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchitis; Female; Heart; Humans; Isoproterenol; Lung; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Propranolol; Respiratory Function Tests | 1984 |
Physical performance and muscle metabolism during beta-adrenergic blockade in man.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Energy Metabolism; Heart Rate; Humans; Hypertension; Lactates; Male; Metoprolol; Muscle Contraction; Muscles; Oxygen Consumption; Physical Endurance; Physical Exertion; Propranolol; Time Factors | 1984 |
Effect of atenolol, metoprolol, and propranolol on isoproterenol-induced tremor and tachycardia in normal subjects.
Topics: Adult; Atenolol; Blood Pressure; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Tachycardia; Tremor | 1981 |
Haemodynamic effects of noise exposure before and after beta 1-selective and non-selective beta-adrenoceptor blockade in patients with essential hypertension.
Topics: Adult; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Noise; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1981 |
[Terbutaline-induced metabolic responses after propranolol and metoprolol].
Topics: Adult; Blood Pressure; Drug Antagonism; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Heart Rate; Hemodynamics; Humans; Lactates; Male; Metoprolol; Potassium; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Terbutaline | 1982 |
Influence of beta-blocking drugs on glucose metabolism in hypertensive, non-diabetic patients.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hypertension; Insulin; Male; Metoprolol; Middle Aged; Patient Compliance; Propanolamines; Propranolol; Protein Binding; Random Allocation | 1983 |
Beta 1 versus nonselective blockade in therapy of essential tremor.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Outcome and Process Assessment, Health Care; Propanolamines; Propranolol; Tremor | 1983 |
Hemodynamic and humoral effects of coffee after beta 1-selective and nonselective beta-blockade.
Topics: Adolescent; Adult; Blood Pressure; Catecholamines; Coffee; Epinephrine; Female; Forearm; Heart Rate; Humans; Male; Metoprolol; Placebos; Propanolamines; Propranolol; Regional Blood Flow; Renin | 1983 |
Beta-adrenoreceptor blocking agents. Their role in reducing chances of recurrent infarction and death.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propranolol; Recurrence; Sympatholytics; Timolol | 1983 |
The effects of acute or chronic ingestion of propranolol or metoprolol on the metabolic and hormonal responses to prolonged, submaximal exercise in hypertensive men.
Topics: Blood Glucose; Catecholamines; Fatty Acids, Nonesterified; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hypertension; Insulin; Lactates; Male; Metoprolol; Physical Exertion; Potassium; Propranolol; Time Factors | 1984 |
[Diurnal variation of angina pectoris attacks. Changes during treatment with beta-blockers].
Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol | 1984 |
Metoprolol and propranolol in migraine prophylaxis: a double-blind multicentre study.
Topics: Adolescent; Adult; Analgesics; Clinical Trials as Topic; Double-Blind Method; Ergotamine; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Propranolol | 1984 |
Metoprolol and propranolol in the prophylactic treatment of classical and common migraine. A double-blind study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hemodynamics; Humans; Long-Term Care; Male; Metoprolol; Middle Aged; Migraine Disorders; Propranolol | 1984 |
Influence of propranolol, metoprolol, and pindolol on mucociliary clearance in patients with coronary heart disease.
Topics: Adult; Aged; Bronchi; Cilia; Coronary Disease; Female; Humans; Lung; Male; Metoprolol; Middle Aged; Mucus; Pindolol; Propranolol; Trachea | 1984 |
The use of the EEG for assessment of vigilance changes caused by beta-blockers.
Topics: Adult; Arousal; Blood Pressure; Electroencephalography; Heart Rate; Humans; Male; Metoprolol; Propranolol; Sleep Stages | 1984 |
The peripheral platelet count and ADP-induced platelet aggregation in response to metoprolol and propranolol as studied in young healthy male volunteers.
Topics: Adenosine Diphosphate; Adult; Heart Rate; Humans; Male; Metoprolol; Platelet Aggregation; Platelet Count; Propranolol | 1983 |
Heart rate and QT interval in subjects adapted to beta-blockade: bradycardia and hypotension as uncorrelated adaptations.
Topics: Adaptation, Physiological; Adult; Aged; Blood Pressure; Electrocardiography; Heart Rate; Humans; Hypertension; Metoprolol; Middle Aged; Physical Exertion; Propranolol | 1983 |
Long acting beta-blockers in the twenty fourth hour.
Topics: Blood Glucose; Blood Pressure; Delayed-Action Preparations; Drug Evaluation; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxygen Consumption; Propranolol | 1983 |
Slower Adaptation of VO2 to steady state of submaximal exercise with beta-blockade.
Topics: Adult; Cardiac Output; Humans; Kinetics; Lactates; Lactic Acid; Male; Metoprolol; Oxygen Consumption; Physical Exertion; Propranolol | 1983 |
Selective and non-selective beta receptor blockade in the reduction of portal pressure in patients with cirrhosis and portal hypertension.
Topics: Cardiac Output; Female; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Metoprolol; Middle Aged; Portal System; Propranolol; Venous Pressure | 1984 |
The effects of acute or chronic ingestion of propranolol or metoprolol on the physiological responses to prolonged, submaximal exercise in hypertensive men.
Topics: Adult; Aged; Blood Pressure; Emotions; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propranolol; Respiration; Sweating; Time Factors | 1984 |
Beta adrenoceptor antagonism and pressor response to phenylephrine.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Phenylephrine; Propranolol | 1984 |
Modification of the metabolic and hormonal response to physical exercise by beta-blocking agents.
Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Glycogen; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Secretion; Lactates; Male; Metoprolol; Physical Exertion; Propanolamines; Propranolol | 1982 |
Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Xerostomia | 1982 |
No effect of propranolol and metoprolol on tolbutamide-stimulated insulin-secretion in hypertensive diabetic and non-diabetic patients.
Topics: Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Humans; Hypertension; Insulin; Insulin Secretion; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Tolbutamide | 1982 |
Failure of propranolol and metoprolol to alter ventilatory responses to carbon dioxide and exercise.
Topics: Adult; Carbon Dioxide; Double-Blind Method; Forced Expiratory Volume; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Placebos; Propanolamines; Propranolol; Respiration | 1980 |
Effect of acute and chronic beta-blockade on carbon dioxide sensitivity in normal man.
Topics: Adult; Atenolol; Carbon Dioxide; Female; Heart Rate; Humans; Hypercapnia; Male; Metoprolol; Propanolamines; Propranolol; Respiratory Function Tests | 1980 |
Metoprolol in angina pectoris complicated by essential hypertension. A clinical comparison of the antianginal efficacy of metoprolol slow-release tablets (Durules) given once daily and propranolol tablets given twice daily.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nitroglycerin; Propanolamines; Propranolol; Tablets | 1981 |
Ambulatory blood pressure during once-daily randomised double-blind administration of atenolol, metoprolol, pindolol, and slow-release propranolol.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Physical Exertion; Pindolol; Propanolamines; Propranolol; Random Allocation; Time Factors | 1982 |
Controlled study of metoprolol and propranolol during prolonged administration in patients with essential tremor.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Long-Term Care; Male; Metoprolol; Middle Aged; Motor Skills; Propanolamines; Propranolol; Tremor | 1982 |
Lack of influence of propranolol and metoprolol on walking distance in patients with chronic intermittent claudication.
Topics: Chronic Disease; Exercise Test; Humans; Intermittent Claudication; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1983 |
Hemodynamic effects of isometric exercise and mental arithmetic in hypertension treated with selective and nonselective beta-blockade.
Topics: Adolescent; Adult; Blood Pressure; Epinephrine; Female; Forearm; Heart Rate; Humans; Hypertension; Isometric Contraction; Male; Mathematics; Mental Processes; Metoprolol; Middle Aged; Physical Exertion; Placebos; Propanolamines; Propranolol; Regional Blood Flow | 1983 |
A comparison of oral metoprolol and propranolol in patients with chronic bronchitis.
Topics: Administration, Oral; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Middle Aged; Peak Expiratory Flow Rate; Placebos; Propanolamines; Propranolol | 1980 |
Circulatory effects of stress in essential hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Hypertension; Metoprolol; Middle Aged; Propranolol; Radioimmunoassay; Random Allocation; Sodium Chloride; Stress, Physiological; Stress, Psychological; Stroke Volume | 1981 |
Long-acting beta-blockers in the twenty-fourth hour. A comparison in hypertension.
Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Time Factors | 1981 |
Metoprolol in high renin hypertension. A comparison with propranolol.
Topics: Adult; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Renal Artery Obstruction; Renin | 1981 |
Metoprolol and propranolol in the treatment of essential hypertension - a long-term comparative study.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Posture; Propanolamines; Propranolol | 1981 |
Metoprolol and propranolol in essential tremor: a double-blind, controlled study.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hand; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Tremor | 1981 |
The effect of propranolol or metoprolol on thermoregulation during insulin-induced hypoglycaemia in man.
Topics: Adult; Body Temperature Regulation; Epinephrine; Heart Rate; Humans; Hypoglycemia; Insulin; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Regional Blood Flow | 1982 |
Response of blood pressure and plasma norepinephrine to propranolol, metoprolol and clonidine during isometric and dynamic exercise in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Clonidine; Exercise Test; Female; Heart Rate; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Propranolol; Rest | 1982 |
Once-daily penbutolol or atenolol can replace combination therapy in essential hypertension.
Topics: Atenolol; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Penbutolol; Propanolamines; Propranolol; Pulse | 1982 |
The effects of a cardioselective (metoprolol) and a nonselective (propranolol) beta-adrenergic blocker on the response to dynamic exercise in normal men.
Topics: Adult; Blood Pressure; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Oxygen Consumption; Physical Exertion; Propanolamines; Propranolol | 1982 |
Selective and nonselective beta-adrenoceptor blockade in hypertension: responses to changes in posture, cold and exercise.
Topics: Blood Pressure; Cold Temperature; Dose-Response Relationship, Drug; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Posture; Propanolamines; Propranolol | 1982 |
Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol.
Topics: Adult; Aged; Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Metoprolol; Middle Aged; Pindolol; Propanolamines; Propranolol; Substance Withdrawal Syndrome | 1982 |
Effect of beta-adrenoceptor blockade on exercise performance and metabolism.
Topics: Adult; Blood Glucose; Catecholamines; Fatty Acids, Nonesterified; Glucagon; Heart Rate; Humans; Lactates; Male; Metoprolol; Physical Exertion; Potassium; Propanolamines; Propranolol | 1981 |
Echocardiographic comparison of haemodynamic effects of metoprolol and propranolol.
Topics: Adult; Cardiac Output; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Male; Metoprolol; Myocardial Contraction; Propanolamines; Propranolol; Vascular Resistance | 1980 |
Lack of effect of propranolol and metoprolol on glucose tolerance in maturity-onset diabetics.
Topics: Diabetes Mellitus; Glucose Tolerance Test; Humans; Metoprolol; Propanolamines; Propranolol | 1980 |
Effects and plasma levels of propranolol and metoprolol in hyperthyroid patients.
Topics: Adult; Aged; Female; Heart Rate; Humans; Hyperthyroidism; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Triiodothyronine | 1980 |
Exercise metabolism during 1 hour of treadmill walking while taking high and low doses of propranolol, metoprolol, or placebo.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Energy Metabolism; Exercise; Exercise Test; Female; Humans; Male; Metoprolol; Propranolol | 1995 |
Reproducibility and consistency of the responses to supine bicycle ergometry; evaluation in conjunction with beta 1-adrenoceptor occupancies.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Celiprolol; Epinephrine; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Reproducibility of Results | 1994 |
Influence of beta-blockade with beta-1-selectivity or intrinsic sympathomimetic activity on some metabolic responses to exercise.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Double-Blind Method; Humans; Lactates; Lactic Acid; Male; Metoprolol; Physical Exertion; Pindolol; Potassium; Propranolol | 1993 |
Influence of beta-blockade with beta-1-selectivity or intrinsic sympathomimetic activity on some cardiorespiratory responses to exercise.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Male; Metoprolol; Peak Expiratory Flow Rate; Physical Exertion; Pindolol; Propranolol | 1993 |
Extent of beta 1- and beta 2-receptor occupancy in plasma assesses the antagonist activity of metoprolol, pindolol, and propranolol in the elderly.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Animals; Double-Blind Method; Female; Humans; Hypertension; Kinetics; Lung; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Reticulocytes | 1993 |
Beta-receptor antagonism does not fully explain esmolol-induced hypotension.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Blood Pressure; Dose-Response Relationship, Drug; Exercise; Humans; Infusions, Intravenous; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol | 1994 |
Effect of selective and nonselective beta-blockade on skeletal muscle excitability and fatiguability.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Double-Blind Method; Electromyography; Exercise Test; Heart Rate; Humans; Isometric Contraction; Male; Metoprolol; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Oxygen Consumption; Propranolol; Sodium-Potassium-Exchanging ATPase | 1994 |
Effects of beta-adrenergic blockade on vasodepressor reaction in patients with vasodepressor syncope.
Topics: Epinephrine; Erythrocyte Membrane; Female; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Norepinephrine; Posture; Propranolol; Receptors, Adrenergic, beta; Sympathetic Nervous System; Syncope; Tilt-Table Test | 1994 |
Inhibition of CYP2D6 activity by treatment with propranolol and the role of 4-hydroxy propranolol.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; Male; Metoprolol; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Phenotype; Propranolol; Recombinant Proteins; Saccharomyces cerevisiae | 1994 |
Lipolysis in burned patients is stimulated by the beta 2-receptor for catecholamines.
Topics: Adolescent; Adult; Blood Urea Nitrogen; Body Surface Area; Burns; Glycerol; Hemodynamics; Humans; Leucine; Lipolysis; Metoprolol; Propranolol; Prospective Studies; Receptors, Adrenergic, beta-2 | 1994 |
Receptor occupancy in lumbar CSF as a measure of the antagonist activity of atenolol, metoprolol and propranolol in the CNS.
Topics: Adrenergic alpha-Antagonists; Adult; Animals; Atenolol; Central Nervous System; Female; Humans; In Vitro Techniques; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Rabbits; Rats; Receptors, Adrenergic, alpha | 1993 |
Why do patients with congestive heart failure tolerate the initiation of beta-blocker therapy?
Topics: Adrenergic beta-Antagonists; Depression, Chemical; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 1993 |
CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Delivery Systems; Exercise; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Propranolol; Psychomotor Performance; Temazepam | 1993 |
Sympathetic influence on cardiovascular responses to sustained head-up tilt in humans.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adult; Blood Pressure; Cardiovascular Physiological Phenomena; Electric Impedance; Heart Rate; Humans; Male; Metoprolol; Oxygen Consumption; Posture; Pressoreceptors; Propranolol; Stroke Volume; Sympathetic Nervous System; Vascular Resistance | 1995 |
Detection of beta-blockers in urine by solid-phase extraction-supercritical fluid extraction and gas chromatography-mass spectrometry.
Topics: Acetic Anhydrides; Acetylation; Adrenergic beta-Antagonists; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Metoprolol; Oxprenolol; Propranolol; Pyridines | 1996 |
Acute effects of beta blockade and exercise on mood and anxiety.
Topics: Adrenergic beta-Antagonists; Adult; Affect; Age Factors; Anxiety; Body Weight; Confusion; Depression; Energy Metabolism; Exercise Test; Exercise Therapy; Fatigue; Female; Humans; Male; Metoprolol; Mood Disorders; Oxygen Consumption; Physical Exertion; Placebos; Propranolol; Sex Factors; Stress, Psychological; Walking | 1996 |
Adrenergic beta 1- and beta 1 + 2-receptor blockade suppress the natural killer cell response to head-up tilt in humans.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Antigens, Surface; Humans; Killer Cells, Natural; Lymphocyte Count; Lymphocyte Subsets; Male; Metoprolol; Posture; Propranolol; Stress, Physiological | 1997 |
Dynamic exercise leads to an increase in circulating ICAM-1: further evidence for adrenergic modulation of cell adhesion.
Topics: Adrenergic beta-Antagonists; Adult; Cell Adhesion; Cell Count; E-Selectin; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Killer Cells, Natural; Male; Metoprolol; Middle Aged; Physical Exertion; Propranolol; Receptors, Adrenergic; Solubility | 1997 |
The effect of beta-blockade on plasma potassium concentrations and muscle excitability following static exercise.
Topics: Action Potentials; Adrenergic beta-Antagonists; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Electromyography; Exercise Test; Femoral Vein; Humans; Isometric Contraction; Lactic Acid; Male; Metoprolol; Muscle, Skeletal; Physical Endurance; Potassium; Propranolol; Sodium-Potassium-Exchanging ATPase; Torque | 1998 |
Effects of beta-blockers on the concentration and oxidizability of plasma lipids.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Heart Rate; Humans; Lipid Metabolism; Lipid Peroxidation; Lipids; Male; Metoprolol; Middle Aged; Propranolol; Prospective Studies; Triglycerides | 1998 |
Micellar liquid chromatography: a worthy technique for the determination of beta-antagonists in urine samples.
Topics: 1-Propanol; Adrenergic beta-Antagonists; Atenolol; Chromatography, Liquid; Ethylamines; Humans; Hydrogen-Ion Concentration; Metoprolol; Micelles; Propranolol; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Surface-Active Agents | 1999 |
Baroreflex sensitivity and the blood pressure response to beta-blockade.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Baroreflex; Blood Pressure; Exercise; Exercise Test; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Pindolol; Prognosis; Propranolol | 1999 |
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Female; Humans; Infant; Long QT Syndrome; Male; Metoprolol; Nadolol; Propranolol; Survival Analysis | 2000 |
Oxygen consumption in patients with hyperthyroidism before and after treatment with beta-blockade versus thyrostatic treatment: a prospective randomized study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Antithyroid Agents; Carbon Dioxide; Female; Humans; Hyperthyroidism; Methimazole; Metoprolol; Middle Aged; Oxygen Consumption; Preoperative Care; Propranolol; Prospective Studies; Treatment Outcome | 2001 |
Influence of beta-adrenoceptor antagonists on the pharmacokinetics of rizatriptan, a 5-HT1B/1D agonist: differential effects of propranolol, nadolol and metoprolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Biological Availability; Cardiovascular System; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Male; Metoprolol; Middle Aged; Nadolol; Propranolol; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2001 |
Clinical manifestations of hyperthyroidism after treatment with selective beta 1 adrenoceptor blocking agents.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Atenolol; Female; Humans; Hyperthyroidism; Male; Metoprolol; Middle Aged; Propranolol; Radioimmunoassay; Thyroid Hormones; Weight Gain | 2003 |
The effect of propranolol, atenolol and metoprolol on the serum levels of thyroxin (T4) and triiodothyronine (T3).
Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Hyperthyroidism; Male; Metoprolol; Middle Aged; Propranolol; Radioimmunoassay; Thyroxine; Triiodothyronine | 2003 |
Scale-up effects on dissolution and bioavailability of propranolol hydrochloride and metoprolol tartrate tablet formulations.
Topics: Adult; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Delayed-Action Preparations; Drug Compounding; Fasting; Female; Humans; Male; Metoprolol; Propranolol; Solubility; Tablets; Therapeutic Equivalency; Weights and Measures | 2000 |
Detrimental effects of beta-blockers in COPD: a concern for nonselective beta-blockers.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Celiprolol; Cross-Over Studies; Double-Blind Method; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Methacholine Chloride; Metoprolol; Middle Aged; Propranolol; Pulmonary Disease, Chronic Obstructive; Pulmonary Ventilation | 2005 |
Effect of beta blockers (metoprolol or propranolol) on effect of simvastatin in lowering C-reactive protein in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; C-Reactive Protein; Cohort Studies; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propranolol; Simvastatin; Treatment Outcome | 2009 |
599 other study(ies) available for propranolol and metoprolol
| Article | Year |
|---|---|
Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted amino)-2-hydroxypropoxy]phenyl]imidazole class. 2.
Topics: Adrenergic beta-Antagonists; Animals; Female; Guinea Pigs; Heart Rate; Hydrogen Bonding; Imidazoles; In Vitro Techniques; Receptors, Adrenergic, beta; Solubility; Structure-Activity Relationship | 1986 |
Synthesis of a series of compounds related to betaxolol, a new beta 1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Antihypertensive Agents; Betaxolol; Biotransformation; Cardiovascular Diseases; Chronic Disease; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Propanolamines; Rana esculenta; Rats; Structure-Activity Relationship | 1987 |
Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class.
Topics: Adrenergic alpha-Agonists; Animals; Female; Guinea Pigs; Heart; Imidazoles; Indicators and Reagents; Isoproterenol; Magnetic Resonance Spectroscopy; Receptors, Adrenergic; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1983 |
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet | 1998 |
LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; CHO Cells; Cricetinae; Cyclopropanes; Female; Humans; Imidazoles; In Vitro Techniques; Ligands; Phenoxypropanolamines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Trachea; Urea | 1999 |
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers.
Topics: Adrenergic beta-Antagonists; Biological Transport; Carrier Proteins; Cells, Cultured; Cimetidine; Hydrogen-Ion Concentration; Kidney; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propranolol; Quinolines | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Inactivation, Metabolic; Liver; Microsomes, Liver; Models, Biological; Permeability; Pharmacokinetics; Rats; Species Specificity | 2002 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
In silico prediction of membrane permeability from calculated molecular parameters.
Topics: Animals; Cell Line; Cell Membrane Permeability; Diffusion; Dogs; Humans; Intestinal Absorption; Models, Biological; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
A 3D-QSAR model for CYP2D6 inhibition in the aryloxypropanolamine series.
Topics: Animals; Cytochrome P-450 CYP2D6 Inhibitors; Humans; Inhibitory Concentration 50; Models, Molecular; Propanolamines; Quantitative Structure-Activity Relationship; Substrate Specificity | 2005 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Role of Tyr(356(7.43)) and Ser(190(4.57)) in antagonist binding in the rat beta1-adrenergic receptor.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Models, Molecular; Mutagenesis, Site-Directed; Propanolamines; Rats; Receptors, Adrenergic, beta-1; Serine; Stereoisomerism; Transfection; Tyrosine | 2006 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cations; Cytochrome P-450 Enzyme System; Disease Models, Animal; Emulsions; Fats; Fatty Liver; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Uncoupling the Structure-Activity Relationships of β2 Adrenergic Receptor Ligands from Membrane Binding.
Topics: Binding Sites; Cell Membrane; Dose-Response Relationship, Drug; Humans; Ligands; Models, Molecular; Molecular Structure; Receptors, Adrenergic, beta-2; Structure-Activity Relationship | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity.
Topics: Antiviral Agents; Cell Line; Humans; Intracellular Signaling Peptides and Proteins; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Structure-Activity Relationship; Thiazoles | 2018 |
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
Once-daily treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Hypertension; Metoprolol; Pindolol; Propranolol; Timolol | 1976 |
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors | 1976 |
Acute hypotensive effect of combined beta1-adrenoceptor blockade and beta2-adrenoceptor stimulation in spontaneously hypertensive rats (SHR).
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Drug Interactions; Heart Rate; Hypertension; Metoprolol; Propranolol; Rats; Terbutaline | 1977 |
Observations in man of hypoglycaemia during selective and non-selective beta-blockade.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Humans; Hypoglycemia; Male; Metoprolol; Middle Aged; Propranolol; Tachycardia | 1977 |
Long term beta-adrenergic blockade reduces tyrosine hydroxylase and dopamine beta-hydroxylase activities in sympathetic ganglia.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dopamine beta-Hydroxylase; Ganglia, Autonomic; Metoprolol; Neural Pathways; Practolol; Propranolol; Rabbits; Time Factors; Tyrosine 3-Monooxygenase | 1977 |
Beta-Adrenoceptor studies. 4. Influence of albumin on in vitro beta-adrenoceptor blocking and antiarrhythmic properties of propranolol, pindolol, practolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Pindolol; Practolol; Propanolamines; Propranolol; Protein Binding; Serum Albumin, Bovine; Trachea | 1977 |
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol | 1977 |
Blockade of isoprenaline-induced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol, metoprolol and acebutolol.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Fatty Acids, Nonesterified; Heart Rate; Humans; Insulin; Isoproterenol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Renin | 1978 |
[Effects of kitchen salt and beta sympatholytics on the course of blood pressure in the hereditary, spontaneously hypertensive rat (SH rats, Münster strain)].
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Metoprolol; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Chloride | 1977 |
[Properties of beta-adrenergic receptors of heart and lung--studies with "cardioselective" beta-receptor blocking substances].
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Binding, Competitive; Heart; Lung; Metoprolol; Oxprenolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1977 |
The release of serotonin from rat duodenal enterochromaffin cells by adrenoceptor agonists studied in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Chromaffin System; Dopamine; Duodenum; Enterochromaffin Cells; Epinephrine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Serotonin | 1978 |
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol | 1978 |
Peripheral platelet count in response to salbutamol before and after adrenergic beta-receptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Albuterol; Blood Platelets; Cell Count; Drug Interactions; Humans; Male; Metoprolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Prevention and reversal of isolation-induced systolic arterial hypertension in rats by treatment with beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart Rate; Hypertension; Male; Metoprolol; Propranolol; Rats; Social Isolation; Time Factors | 1979 |
Beta-2-blocking effect of metoprolol.
Topics: Adrenergic beta-Antagonists; Humans; Lymphocytes; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1979 |
Beta-adrenergic blockade and vasospasm.
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Propranolol; Raynaud Disease; Vasoconstriction | 1979 |
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol | 1979 |
Long-term haloperidol-treatment of mice: a change in beta-adrenergic receptor responsiveness.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Haloperidol; Male; Metoprolol; Mice; Motor Activity; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1979 |
Inhibition and facilitation of lacrimal flow by beta-adrenergic drugs.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cholinergic Fibers; Electric Stimulation; Heart Rate; Isoproterenol; Lacrimal Apparatus; Metoprolol; Organ Culture Techniques; Propranolol; Rabbits; Receptors, Adrenergic, beta; Secretory Rate; Sodium Chloride; Tears | 1979 |
Beta-adrenoceptor blockade by atenolol, metoprolol and propranolol in the anaesthetized cat.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Female; Heart Rate; Hemodynamics; Hindlimb; Isoproterenol; Male; Metoprolol; Muscle Relaxation; Propanolamines; Propranolol; Regional Blood Flow; Vasodilation | 1979 |
Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Circulation; Cardiac Output; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature; Timolol | 1979 |
Effects of beta-adrenoreceptor antagonists on sino-aortic baroreflex sensitivity and blood pressure in hypertensive man.
Topics: Acebutolol; Adolescent; Adrenergic beta-Agonists; Adult; Aging; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Pressoreceptors; Propranolol; Sinoatrial Node; Time Factors | 1979 |
Effects of adrenergic beta-blockers and a membrane stabilizing agent on ouabain-induced cardiac arrhythmias in anaesthetized guinea pigs.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Guinea Pigs; Lidocaine; Male; Metoprolol; Ouabain; Propranolol | 1979 |
The peripheral platelet count and the isoprenaline-induced splenic platelet pooling in response to beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Blood Platelets; Female; Heart Rate; Hematocrit; Humans; Isoproterenol; Male; Metoprolol; Platelet Count; Propranolol; Spleen | 1979 |
Acute effects of propranolol and metoprolol on plasma concentrations of parathyroid hormone and calcitonin in uraemic patients.
Topics: Adult; Bicarbonates; Blood Proteins; Calcitonin; Calcium; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Male; Metoprolol; Parathyroid Hormone; Phosphates; Propanolamines; Propranolol; Uremia | 1979 |
Propranolol therapy for secondary hyperparathyroidism in uraemia.
Topics: Calcitonin; Drug Therapy, Combination; Humans; Hyperparathyroidism, Secondary; Metoprolol; Parathyroid Hormone; Propranolol; Uremia | 1978 |
Beta-blocker withdrawal syndrome?
Topics: Atenolol; Humans; Male; Metoprolol; Propanolamines; Propranolol; Substance Withdrawal Syndrome | 1979 |
Beta-blocker withdrawal syndrome.
Topics: Humans; Metoprolol; Nifedipine; Propanolamines; Propranolol; Pyridines; Substance Withdrawal Syndrome; Timolol | 1979 |
Influence of once-daily administration of beta-adrenoceptor antagonists on arterial pressure and its variability.
Topics: Acebutolol; Activities of Daily Living; Adolescent; Adult; Bed Rest; Blood Pressure; Circadian Rhythm; Diastole; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Propranolol; Sleep; Systole | 1979 |
Influence of beta blockade on the renin-angiotensin-aldosterone system [proceedings].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Renin | 1979 |
Responses of the denervated rat urinary bladder to alfa adrenoceptor stimulation.
Topics: Animals; Denervation; Dihydroergotamine; Electric Stimulation; Male; Methacholine Compounds; Metoprolol; Muscle Contraction; Norepinephrine; Parasympathetic Nervous System; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Urinary Bladder | 1976 |
The effect of local anaesthetics on the thyrotropin receptor-adenylate cyclase system.
Topics: Adenylyl Cyclases; Anesthetics, Local; Humans; Metoprolol; Polyphloretin Phosphate; Practolol; Propranolol; Quinidine; Receptors, Cell Surface; Thyroid Gland; Thyrotropin | 1976 |
Tremor caused by sympathomimetics is mediated by beta2-adrenoreceptors.
Topics: Blood Pressure; Heart Rate; Humans; Informed Consent; Metoprolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sympathomimetics; Terbutaline; Tremor | 1977 |
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation.
Topics: Animals; Blood Pressure; Catheterization; Cats; Drug Interactions; Electric Stimulation; Female; Hypothalamus; Isoproterenol; Male; Metoprolol; Practolol; Procaine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism; Tolazoline | 1977 |
Identification of the receptor involved in adrenaline mediated sweating in the horse.
Topics: Animals; Epinephrine; Hematocrit; Horses; Metoprolol; Phenylephrine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sweating | 1977 |
Importance of cardiac and vascular beta-receptors in the action of phentolamine.
Topics: Animals; Blood Pressure; Blood Vessels; Cardiac Output; Cats; Female; Heart; Male; Metoprolol; Phentolamine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1977 |
Hormone action at the membrane level. VI. Binding of (-)-[3H]dihydroalprenolol and (+/-)-[3H]isoproterenol to turkey erythrocytes and correlation with adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Female; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Turkeys | 1978 |
Influence of selective and non-selective beta-adrenoreceptor blockade on the haemodynamic effect of adrenaline during combined antihypertensive drug therapy.
Topics: Adult; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Metoprolol; Middle Aged; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Regional Blood Flow; Vascular Resistance | 1979 |
Limitation of work performance in normal adult males in the presence of beta-adrenergic blockade.
Topics: Adult; Blood Pressure; Fatigue; Fatty Acids, Nonesterified; Heart Rate; Hemodynamics; Humans; Lactates; Male; Metoprolol; Oxygen Consumption; Physical Exertion; Propanolamines; Propranolol | 1979 |
Angiotensin II blockade during combined thiazide-beta-adrenoreceptor-blocker treatment.
Topics: Adult; Angiotensin II; Atenolol; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Plasma Volume; Propanolamines; Propranolol; Renin; Saralasin; Sodium | 1979 |
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil | 1979 |
Treatment of essential tremor with metoprolol.
Topics: Aged; Humans; Male; Metoprolol; Premedication; Propanolamines; Propranolol; Tremor | 1979 |
Red cell changes in hyperthyroidism.
Topics: Adolescent; Adult; Aged; Carbimazole; Erythrocyte Indices; Female; Follow-Up Studies; Hemoglobins; Humans; Hyperthyroidism; Iodine Radioisotopes; Male; Metoprolol; Middle Aged; Propranolol | 1979 |
Protein synthesis and composition of cardiac and vascular tissue in spontaneously hypertensive rats and the effects of beta-adrenergic antagonist treatment.
Topics: Animals; Heart; Hypertension; Hypertrophy; Male; Metoprolol; Muscle Proteins; Muscle, Smooth, Vascular; Myocardium; Propanolamines; Propranolol; Rats | 1979 |
Stimulation of normal and abnormal neutrophil motility in vitro by dexpropranolol, metoprolol and sotalol.
Topics: Adult; Cell Movement; Chemotaxis, Leukocyte; Female; Humans; In Vitro Techniques; Male; Metoprolol; Neutrophils; Propanolamines; Propranolol; Sotalol | 1979 |
The actions of the beta-adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse.
Topics: Animals; Blood Glucose; Carbon Dioxide; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Hematocrit; Horses; Humans; Lactates; Metoprolol; Muscles; Norepinephrine; Physical Exertion; Propanolamines; Propranolol; Sweating | 1979 |
[Muscle blood flow during orciprenaline stimulation and beta sympathicolysis with propranolol and metoprolol].
Topics: Depression, Chemical; Humans; Leg; Metaproterenol; Metoprolol; Muscles; Plethysmography, Impedance; Propanolamines; Propranolol; Regional Blood Flow; Stimulation, Chemical | 1977 |
Metoprolol--a new cardioselective beta adrenoceptor antagonist in experimental cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Cats; Dogs; Female; Guinea Pigs; Male; Metoprolol; Propanolamines; Propranolol | 1978 |
Selectivity and steric effects of metoprolol isomers on isolated rabbit atria, arteries and tracheal muscles.
Topics: Animals; Arteries; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Propanolamines; Propranolol; Rabbits; Species Specificity; Stimulation, Chemical; Trachea | 1978 |
Beta blockade in diabetes.
Topics: Cardiovascular System; Diabetes Mellitus; Humans; Hypoglycemia; Metoprolol; Propanolamines; Propranolol | 1978 |
Haemodynamic effects of the beta-receptor blocking agents metoprolol and propranolol in the anesthetized dog.
Topics: Animals; Blood Pressure; Dogs; Heart; Hemodynamics; Metoprolol; Propanolamines; Propranolol; Vascular Resistance | 1978 |
Enhancement of the bioavailability of propranolol and metoprolol by food.
Topics: Administration, Oral; Adult; Biological Availability; Female; Food; Humans; Kinetics; Male; Metoprolol; Propanolamines; Propranolol; Time Factors | 1977 |
Effect of cardioselective beta-blockade by metoprolol on the phasic myocardial blood content and epi/endocardial ratio.
Topics: Animals; Coronary Circulation; Guinea Pigs; Heart; Male; Metoprolol; Practolol; Propanolamines; Propranolol | 1977 |
The actions of the beta-adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse [proceedings].
Topics: Animals; Heart Rate; Horses; Metoprolol; Norepinephrine; Physical Exertion; Propanolamines; Propranolol | 1977 |
Studies with a new cardioselective beta-blocker, metoprolol.
Topics: Adult; Blood Pressure; Blood Vessels; Bronchi; Epinephrine; Hemodynamics; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Renin | 1976 |
Sympathetic and immune interactions during dynamic exercise. Mediation via a beta 2-adrenergic-dependent mechanism.
Topics: Adult; Catecholamines; Concanavalin A; Female; Humans; Immune System; Killer Cells, Natural; Lymphocyte Subsets; Lymphocytes; Male; Metoprolol; Physical Exertion; Propranolol; Receptors, Adrenergic, beta; Receptors, Interleukin-2; Sympathetic Nervous System; Thymidine | 1992 |
Membrane stabilizing activity and beta-adrenoceptor antagonist-induced bradycardia in conscious dogs.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Bradycardia; Consciousness; Dogs; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Block; Heart Rate; Heart Ventricles; Male; Membranes; Metoprolol; Penbutolol; Pindolol; Propranolol; Refractory Period, Electrophysiological; Stereoisomerism; Ventricular Function | 1992 |
Lipophilic beta-blockers inhibit monocyte and endothelial cell-mediated modification of low density lipoproteins.
Topics: Adrenergic beta-Antagonists; Cell Line; Copper; Endothelium, Vascular; Humans; Lipoproteins, LDL; Metoprolol; Molecular Structure; Monocytes; Oxidation-Reduction; Pindolol; Propranolol | 1992 |
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cocaine; Dioxanes; Drug Interactions; Heart Rate; Idazoxan; Male; Metoprolol; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation; Yohimbine | 1992 |
Receptor pharmacology of carvedilol in the human heart.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Metoprolol; Myocardium; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
[The action of the new beta-adrenoblocker Lopressor on the hemodynamics of hypertension patients].
Topics: Adult; Drug Evaluation; Hemodynamics; Humans; Hypertension; Metoprolol; Middle Aged; Propranolol; Tablets; Time Factors | 1992 |
Metoprolol and propranolol treatment in carbon tetrachloride-induced hepatic injury.
Topics: Aminopyrine N-Demethylase; Animals; Bilirubin; Blood Glucose; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Liver Glycogen; Male; Metoprolol; Mixed Function Oxygenases; Propranolol; Rats; Rats, Wistar | 1992 |
Simultaneous determination of propranolol or metoprolol in the presence of benzodiazepines in the plasma by gas chromatography.
Topics: Benzodiazepines; Chromatography, Gas; Humans; Metoprolol; Propranolol | 1992 |
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol | 1991 |
Paradoxal pharmacologic effects observed with beta-blocker agents on cardiac cells in culture.
Topics: Adrenergic beta-Antagonists; Animals; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Heart; Metoprolol; Propranolol; Rats; Rats, Inbred Strains | 1991 |
Response to beta-blockers in maternal and fetal rat hearts in vitro.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Female; Heart; Heart Rate; Isoproterenol; Labetalol; Metoprolol; Pregnancy; Pregnancy, Animal; Propranolol; Rats; Rats, Inbred Strains | 1991 |
Effects of acute cardioselective and non-selective beta-adrenergic blockade on left-ventricular volumes and vascular resistance at rest and during exercise.
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Output; Cardiovascular Physiological Phenomena; Cardiovascular System; Exercise; Heart Rate; Heart Ventricles; Humans; Male; Metoprolol; Propranolol; Vascular Resistance; Ventricular Function | 1991 |
The role of the adrenoceptors in the activation of the hypothalamic-pituitary-testicular complex of mice induced by the presence of a female.
Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Hypothalamo-Hypophyseal System; Male; Metoprolol; Mice; Mice, Inbred CBA; Phentolamine; Prazosin; Propanolamines; Propranolol; Radioimmunoassay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sexual Behavior, Animal; Testis; Testosterone; Yohimbine | 1991 |
Comparisons of the combined contributions of agonist binding frequency and intrinsic efficiency to receptor-mediated activation of adenylate cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Metoprolol; Mice; Propranolol; Receptors, Adrenergic, beta | 1991 |
Preservation of membrane phospholipids by propranolol, pindolol, and metoprolol: a novel mechanism of action of beta-blockers.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Fatty Acids; Heart Rate; Lipid Peroxidation; Male; Membrane Lipids; Metoprolol; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Reperfusion Injury | 1991 |
The effect of adrenergic agonists and antagonists on cysteine-proteinase inhibitor (cystatin) in rat saliva.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Blotting, Western; Cysteine Proteinase Inhibitors; Dobutamine; Electrophoresis, Polyacrylamide Gel; Female; Isoproterenol; Methamphetamine; Methoxamine; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioimmunoassay; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides; Terbutaline | 1991 |
Beta adrenoceptors mediate the catecholamine-induced stimulation of oxytocin secretion from cultured bovine granulosa cells.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cattle; Cells, Cultured; Dobutamine; Epinephrine; Female; Granulosa Cells; Metoprolol; Norepinephrine; Oxytocin; Phentolamine; Practolol; Propranolol; Receptors, Adrenergic, beta | 1991 |
Transport of beta-blockers and calcium antagonists by diffusion in cat myocardium.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Biological Transport; Calcium Channel Blockers; Cats; Diffusion; In Vitro Techniques; Metoprolol; Myocardium; Propranolol; Sucrose; Verapamil | 1991 |
Long-term results of migraine prophylaxis with flunarizine and beta-blockers.
Topics: Adult; Aged; Female; Flunarizine; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Prognosis; Propranolol; Time Factors | 1991 |
[The use of obzidan and metoprolol in patients with supraventricular systolic tachyarrhythmias].
Topics: Adolescent; Adult; Drug Evaluation; Female; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Ovary; Propranolol; Tachycardia, Supraventricular; Testis; Thyroid Gland | 1991 |
[Effect of propranolol and metoprolol on cardiorespiratory and metabolic response to exercise].
Topics: Animals; Dogs; Hemodynamics; Metoprolol; Oxygen Consumption; Physical Exertion; Propranolol; Respiration; Rest | 1991 |
Screening and confirmatory analysis of beta-agonists, beta-antagonists and their metabolites in horse urine by capillary gas chromatography-mass spectrometry.
Topics: Administration, Oral; Animals; Clenbuterol; Doping in Sports; Gas Chromatography-Mass Spectrometry; Horses; Injections, Intravenous; Isoxsuprine; Metoprolol; Propranolol; Timolol | 1991 |
Inhibition of hypothalamic somatostatin release by beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Clonidine; Growth Hormone; Hypothalamus; Labetalol; Male; Metoprolol; Ouabain; Pituitary Gland, Anterior; Propranolol; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
B cell adrenoceptors and sulphonylurea-induced insulin release in mouse islets.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Female; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Tolbutamide | 1990 |
The effect of beta-adrenergic blockade on leg blood flow with repeated maximal contractions of the triceps surae muscle group in man.
Topics: Adrenergic beta-Antagonists; Adult; Heart Rate; Humans; Leg; Male; Metoprolol; Muscle Contraction; Oxprenolol; Propranolol; Regional Blood Flow | 1990 |
Separation of the enantiomers of beta-receptor blocking agents and other cationic drugs using a CHIRAL-AGP column. Binding properties and characterization of immobilized alpha 1-acid glycoprotein.
Topics: Adrenergic beta-Antagonists; Adsorption; Alprenolol; Atenolol; Binding Sites; Butylamines; Chromatography; Metoprolol; Molecular Structure; Orosomucoid; Oxprenolol; Pindolol; Propranolol; Protein Conformation; Spectrometry, Fluorescence; Stereoisomerism | 1990 |
Parasympathetic nervous system in patients with Graves' disease determined by R-R interval variations on electrocardiogram.
Topics: Adrenergic alpha-Antagonists; Adult; Electrocardiography; Female; Graves Disease; Humans; Male; Metoprolol; Parasympathetic Nervous System; Propranolol; Quinazolines; Receptors, Adrenergic, beta | 1990 |
[Beta-receptor blocking effect in human by propranolol and metoprolol].
Topics: Adult; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Propranolol | 1990 |
Assessment of the beta 2 adrenoceptor and Ca2+ channel-blocking activity of drugs with the rat portal vein.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dobutamine; Isoproterenol; Male; Metoprolol; Muscle Contraction; Portal Vein; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Verapamil | 1990 |
A pressor effect of noncardioselective beta-blockers in mildly hypertensive patients during acute hospitalization.
Topics: Adult; Aged; Aged, 80 and over; Atenolol; Blood Pressure; Echocardiography; Female; Heart Rate; Hospitalization; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Stress, Psychological | 1990 |
Effect of aging on the pharmcokinetics of atenolol, metoprolol and propranolol in the rat.
Topics: Aging; Animals; Antipyrine; Atenolol; Male; Metabolic Clearance Rate; Metoprolol; Orosomucoid; Propranolol; Rats; Rats, Inbred Strains | 1990 |
Isoflurane--a study of its adrenoceptor interaction in the isolated rat parotid gland.
Topics: 2,4-Dinitrophenol; Amylases; Animals; Dinitrophenols; Dose-Response Relationship, Drug; Female; Isoflurane; Methyl Ethers; Metoprolol; Oxidative Phosphorylation; Parotid Gland; Potassium; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Rubidium | 1986 |
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metoprolol; Myocardial Contraction; Pindolol; Propranolol; Time Factors; Ventricular Fibrillation | 1987 |
The effect of beta-blockade on platelet function and fibrinolytic activity.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Platelets; Catecholamines; Cyclic AMP; Epinephrine; Fibrinolysis; Humans; Metoprolol; Middle Aged; Platelet Aggregation; Propranolol | 1987 |
Antiarrhythmic effects of selective beta 1- and beta 2- and nonselective beta-adrenoceptor blockade in normokalaemic and dietary-induced hypokalaemic rats.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Coronary Vessels; Diet; Heart Rate; Hypokalemia; Isoproterenol; Male; Metoprolol; Potassium; Propanolamines; Propranolol; Rats; Rats, Inbred Strains | 1989 |
alpha-Fluoromethylhistidine decreases the histamine content of the rat right atrium under the influence of sympathetic activity.
Topics: Animals; Heart; Histamine; Histidine; Hydroxydopamines; In Vitro Techniques; Male; Methylhistidines; Metoprolol; Myocardium; Oxidopamine; Propranolol; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Sympathetic Nervous System; Time Factors | 1989 |
Adipose tissue and skeletal muscle blood flow during mental stress.
Topics: Adipose Tissue; Adult; Blood Flow Velocity; Blood Pressure; Conflict, Psychological; Epinephrine; Glycerol; Heart Rate; Humans; Male; Metoprolol; Muscles; Propranolol; Receptors, Adrenergic, beta; Stress, Physiological; Vascular Resistance; Vasodilation; Xenon Radioisotopes | 1989 |
Evidence for the role of epinephrine binding frequency in activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Diffusion; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Kinetics; Metoprolol; Mice; Propranolol; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure; Humans; Infant; Isoproterenol; Metoprolol; Mitral Valve Stenosis; Myocardium; Propranolol; Receptors, Adrenergic, beta; Sotalol; Tetralogy of Fallot | 1989 |
Three binding sites of 125I-iodocyanopindolol, i.e. beta 1, beta 2-adrenergic and 5HT1B-serotonergic receptors in rat brain determined by the displacement and Scatchard analysis.
Topics: Animals; Binding, Competitive; Brain; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Mathematics; Membranes; Metoprolol; Pindolol; Propranolol; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin | 1989 |
[Effect of selective and non-selective adrenergic beta receptor blockaders on selected electrophysiologic properties of the human heart].
Topics: Action Potentials; Adult; Atrial Function; Atrioventricular Node; Drug Evaluation, Preclinical; Female; Heart Atria; Heart Conduction System; Heart Function Tests; Humans; Male; Metoprolol; Middle Aged; Propranolol; Receptors, Adrenergic, beta; Sinoatrial Node | 1989 |
Influence of topical and systemic beta-blockers on tear production.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Butoxamine; Drug Administration Routes; Injections, Intramuscular; Lacrimal Apparatus; Male; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Rabbits; Time Factors; Timolol | 1989 |
Efficacy of low-dose metoprolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Psychomotor Agitation; Schizophrenia | 1989 |
Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney.
Topics: Adrenergic beta-Antagonists; Animals; Isoproterenol; Kidney; Male; Metoprolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin; Secretory Rate; Species Specificity | 1989 |
Paired stimulation and functional change of the sural nerve during beta blocker therapy.
Topics: Adrenergic beta-Antagonists; Adult; Electric Stimulation; Female; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Neural Conduction; Propranolol; Reaction Time; Spinal Nerves; Sural Nerve | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nadolol; Nifedipine; Nitrates; Nitroglycerin; Propranolol; Verapamil | 1989 |
Serum potassium concentrations following succinylcholine in patients undergoing beta-adrenoceptor blocking therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Heart Rate; Humans; Metoprolol; Middle Aged; Nadolol; Ophthalmic Solutions; Potassium; Propranolol; Succinylcholine; Time Factors; Timolol | 1989 |
Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat.
Topics: Administration, Oral; Animals; Antipyrine; Inflammation; Injections, Intravenous; Male; Metoprolol; Orosomucoid; Propranolol; Protein Binding; Rats; Rats, Inbred Strains; Turpentine | 1989 |
Stimulation of beta-adrenoceptors inhibits lordosis behavior in the female rat.
Topics: Animals; Estradiol; Female; Isomerism; Lidocaine; Metoprolol; Pindolol; Posture; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sexual Behavior, Animal | 1988 |
Beta adrenergic receptors in human cavernous tissue.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Binding Sites; Ethanolamines; Humans; Iodine Radioisotopes; Iodocyanopindolol; Male; Metoprolol; Penis; Pindolol; Practolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1985 |
Are beta-adrenergic mechanisms involved in ocular hypotensive actions of adrenergic drugs?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Aqueous Humor; Butoxamine; Cats; Dihydroalprenolol; Female; Intraocular Pressure; Male; Metoprolol; Propanolamines; Propranolol; Timolol | 1985 |
Tolerability of combined treatment with verapamil and beta-blockers in angina resistant to monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Drug Therapy, Combination; Drug Tolerance; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Verapamil | 1985 |
Training-induced bradycardia in rats on cardioselective and non-selective beta receptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Bradycardia; Female; Heart Rate; Metoprolol; Physical Exertion; Propranolol; Rats; Rats, Inbred Strains | 1985 |
Side-effects of beta-adrenoceptor blocking drugs assessed by visual analogue scales.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Metoprolol; Oxprenolol; Propranolol; Surveys and Questionnaires | 1985 |
Exercise training during chronic beta blockade in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Coronary Artery Bypass; Female; Heart Rate; Humans; Male; Metoprolol; Myocardial Infarction; Nadolol; Physical Exertion; Propanolamines; Propranolol; Timolol | 1985 |
Effects and adverse effects of autonomic blockade in physical exercise.
Topics: Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Fatigue; Heart Rate; Humans; Metoprolol; Oxygen Consumption; Physical Exertion; Propranolol; Rats | 1985 |
Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.
Topics: Animals; Antipsychotic Agents; Benzamides; Catecholamines; Chlorpromazine; Consciousness; Haloperidol; Male; Metoprolol; Pimozide; Prazosin; Prolactin; Propranolol; Rabbits; Radioimmunoassay; Yohimbine | 1985 |
Chronopharmacokinetics of beta-receptor blocking drugs of different lipophilicity (propranolol, metoprolol, sotalol, atenolol) in plasma and tissues after single and multiple dosing in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Chemical Phenomena; Chemistry, Physical; Half-Life; Heart Rate; Kinetics; Male; Metoprolol; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Structure-Activity Relationship; Time Factors; Tissue Distribution | 1985 |
Beta adrenergic influence on esophageal and colonic motility in man.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Colon; Colonic Diseases, Functional; Esophagus; Female; Gastrointestinal Motility; Humans; Male; Manometry; Metoprolol; Middle Aged; Parasympatholytics; Practolol; Prenalterol; Propranolol; Sincalide; Terbutaline | 1985 |
Beta-blocker brain concentrations in man.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Brain Chemistry; Cats; Humans; Lipid Metabolism; Metoprolol; Oxprenolol; Propranolol; Rats; Solubility; Species Specificity; Subarachnoid Hemorrhage; Tissue Distribution | 1985 |
Effect of beta-blockers on psychomotor performance in normal volunteers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anxiety; Arousal; Atenolol; Diazepam; Drug Interactions; Electroencephalography; Emotions; Evoked Potentials; False Positive Reactions; Female; Health Planning; Humans; Kinetics; Male; Methyldopa; Metoprolol; Propranolol; Psychometrics; Psychomotor Performance; Reaction Time; Reference Values; Reserpine; Time Factors; Visual Acuity | 1985 |
Polymorphic metabolism of the beta-adrenoreceptor blocking drugs and its clinical relevance.
Topics: Adrenergic beta-Antagonists; Animals; Biological Availability; Blood Pressure; Debrisoquin; Ethanolamines; Glucuronates; Humans; Hydroxylation; Kinetics; Lipids; Metoprolol; Phenotype; Polymorphism, Genetic; Propranolol; Solubility; Structure-Activity Relationship; Timolol | 1985 |
Side-effects of beta-blockers assessed using visual analogue scales.
Topics: Acebutolol; Adrenergic beta-Antagonists; Analysis of Variance; Atenolol; Dreams; Fatigue; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 1985 |
Single-dose kinetics of oral propranolol, metoprolol, atenolol, and sotalol: relation to lipophilicity.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics; Lipids; Male; Metoprolol; Propranolol; Solubility; Sotalol | 1985 |
A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Blood Proteins; Female; Half-Life; Humans; Hypertension; Kinetics; Male; Metoprolol; Oxprenolol; Propranolol; Protein Binding | 1985 |
Further evidence of the inhibitory role of perifornical hypothalamic beta-adrenergic receptors in the feeding behaviour of hungry rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Clenbuterol; Diethylpropion; Feeding Behavior; Hypothalamus; Male; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
[Effect of 3-month treatment with propranolol, oxprenolol, metoprolol and pindolol on plasma lipids and lipoproteins in patients with primary arterial hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Oxprenolol; Pindolol; Propranolol; Time Factors | 1985 |
Effects of beta 1- vs. beta 1- beta 2-blockade on training adaptations in rat skeletal muscle.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Citrate (si)-Synthase; Heart Rate; L-Lactate Dehydrogenase; Male; Metoprolol; Muscles; Physical Conditioning, Animal; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
The effect of beta-adrenergic blockade on the myopathic changes in experimental hyperthyroidism in rats.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Hyperthyroidism; Male; Metoprolol; Microscopy, Electron; Muscles; Organ Size; Propranolol; Rats; Triiodothyronine | 1986 |
Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.
Topics: Acebutolol; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Blood Pressure; Decerebrate State; Heart; Heart Rate; Hypertension; Isoproterenol; Levobunolol; Male; Metoprolol; Oxprenolol; Propranolol; Rats; Rats, Inbred SHR; Renin; Sympathetic Nervous System; Sympathomimetics; Time Factors | 1986 |
Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Debrisoquin; Genetic Variation; Humans; Hypertension; Isoquinolines; Kinetics; Male; Metoprolol; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Propranolol; Structure-Activity Relationship; Timolol | 1986 |
Binding to serum alpha 1-acid glycoprotein and effect of beta-adrenoceptor antagonists in rats with inflammation.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart Rate; Inflammation; Injections, Intravenous; Male; Metoprolol; Orosomucoid; Oxprenolol; Portal Vein; Propranolol; Protein Binding; Rats; Rats, Inbred Strains | 1986 |
Determination of the new beta-blocker bisoprolol and of metoprolol, atenolol and propranolol in plasma and urine by high-performance liquid chromatography.
Topics: Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Kinetics; Metoprolol; Propanolamines; Propranolol | 1986 |
Effects of beta-blocking agents on urinary excretion of 3-methylhistidine during experimental hyperthyroidism in rats.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Histidine; Hyperthyroidism; Male; Methylhistidines; Metoprolol; Muscle Proteins; Propranolol; Rats; Triiodothyronine | 1987 |
Contingent negative variation and efficacy of beta-blocking agents in migraine.
Topics: Adrenergic beta-Antagonists; Adult; Contingent Negative Variation; Electrophysiology; Female; Humans; Male; Metoprolol; Migraine Disorders; Propranolol | 1986 |
Beta-adrenoceptor blockade, platelets, and rheologic factors.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic beta-Antagonists; Erythrocytes; Fibrinolysis; Humans; Lipoproteins; Metoprolol; Migraine Disorders; Platelet Aggregation; Propranolol; Rheology; Thromboxane B2 | 1986 |
Effects of selective and non-selective beta-blockers on the alanine and free fatty acid responses to glucagon challenge in hemodialysis patients.
Topics: Adrenergic beta-Antagonists; Adult; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Humans; Metoprolol; Middle Aged; Propranolol; Renal Dialysis | 1986 |
Specialization in beta-1 and beta-2 adrenoceptor distribution in veins of the rabbit face: relationship to myogenic tone and sympathetic nerve innervation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Catechols; Electrophysiology; Face; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tetrodotoxin; Veins | 1987 |
Influence of beta-blocker coadministration on the kinetics of isosorbide mononitrate and dinitrate.
Topics: Adrenergic beta-Antagonists; Adult; Drug Interactions; Female; Humans; Isosorbide Dinitrate; Male; Metipranolol; Metoprolol; Propranolol | 1986 |
Protein degradation in skeletal muscle during experimental hyperthyroidism in rats and the effect of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Eating; Hyperthyroidism; Male; Metoprolol; Muscle Proteins; Muscles; Propranolol; Rats; Rats, Inbred Strains; Triiodothyronine | 1987 |
Comparative study of the effect of beta-blockers with different pharmacological properties on cholesteryl ester formation in mouse peritoneal macrophages.
Topics: Adrenergic beta-Antagonists; Animals; Cholesterol Esters; Female; Macrophages; Metoprolol; Mice; Oleic Acid; Oleic Acids; Peritoneal Cavity; Pindolol; Propranolol; Sterol O-Acyltransferase; Triglycerides | 1987 |
Blockade of central beta-adrenoceptors attenuates tremor induced by 5-hydroxytryptamine (5-HT)-receptor activation in rats.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Male; Methoxydimethyltryptamines; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sotalol; Tremor | 1987 |
Beta-adrenoceptor blockade, alpha-stimulation and changes in plasma potassium concentration after suxamethonium administration in dogs.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Metoprolol; Phenylephrine; Potassium; Propanolamines; Propranolol; Succinylcholine; Time Factors | 1987 |
Prejunctional beta 2-adrenoreceptor blockade reduces nerve stimulation evoked release of endogenous noradrenaline in skeletal muscle in situ.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Metoprolol; Muscles; Neuromuscular Junction; Norepinephrine; Propranolol; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 1987 |
Depressed melatonin secretion in patients with nightmares due to beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Atenolol; Dreams; Female; Hallucinations; Humans; Male; Melatonin; Metoprolol; Middle Aged; Propranolol | 1987 |
Lipophilic beta-adrenoceptor antagonists stimulate cholesterol biosynthesis in human skin fibroblasts.
Topics: Adrenergic beta-Antagonists; Cholesterol; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Labetalol; Metoprolol; Pindolol; Propanolamines; Propranolol; Skin; Stereoisomerism | 1987 |
Comparison of hemodynamic responses to isoproterenol infusion and surgical stress in patients given cardioselective and noncardioselective beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Atenolol; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Evaluation; Heart; Heart Rate; Hemodynamics; Humans; Isoproterenol; Metoprolol; Propranolol; Receptors, Adrenergic, beta; Stimulation, Chemical; Stress, Physiological; Time Factors | 1987 |
[Lipoprotein metabolism and beta receptor blockers].
Topics: Adrenergic beta-Antagonists; Atenolol; Cholesterol, HDL; Humans; Hyperlipoproteinemias; Lipoproteins; Metoprolol; Propranolol; Risk; Triglycerides | 1987 |
Effect of beta-blockers on the relation between QT-interval and heart rate in exercise ECG.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Heart Rate; Humans; Metoprolol; Myocardial Infarction; Propranolol; Regression Analysis; Retrospective Studies | 1987 |
[Correlations between beta blockers and the induction of psoriasis].
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Humans; Male; Metoprolol; Middle Aged; Propranolol; Psoriasis | 1987 |
Effect of beta-adrenergic blockade on the growth rate of abdominal aortic aneurysms.
Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Aortic Aneurysm; Atenolol; Female; Humans; Male; Metoprolol; Propranolol; Retrospective Studies; Ultrasonography | 1988 |
Simultaneous assessment of membrane-stabilizing and beta-adrenoceptor blocking activity of drugs with the rat isolated left atria.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Cell Membrane; Electric Stimulation; Heart Atria; Isoproterenol; Male; Metoprolol; Models, Biological; Myocardial Contraction; Procaine; Propranolol; Rats; Rats, Inbred Strains | 1988 |
Platelet activity and selective beta-blockade in migraine prophylaxis.
Topics: Adenosine Diphosphate; Adolescent; Adrenergic beta-Antagonists; Adult; Blood Platelets; Epinephrine; Humans; Metoprolol; Middle Aged; Migraine Disorders; Propanolamines; Propranolol | 1988 |
Antihypertensive effect of beta blockade in renal transplant recipients with or without host kidneys.
Topics: Adrenergic beta-Antagonists; Angiotensins; Atenolol; Humans; Hypertension, Renal; Kidney; Kidney Transplantation; Metoprolol; Nephrectomy; Propranolol; Renin; Retrospective Studies | 1988 |
Effects of atenolol and some other beta-adrenoceptor blocking agents on norepinephrine-induced responses in isolated and perfused rat hearts.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart; Heart Rate; In Vitro Techniques; Male; Metoprolol; Myocardial Contraction; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Timolol | 1988 |
Systemic phenoxybenzamine but not beta-adrenergic antagonists block noradrenergic inhibition of cerebellar Purkinje and hippocampal pyramidal neurons.
Topics: Adrenergic beta-Antagonists; Animals; Cerebellum; gamma-Aminobutyric Acid; Hippocampus; Male; Metoprolol; Neurons; Norepinephrine; Phenoxybenzamine; Propanolamines; Propranolol; Purkinje Cells; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values | 1988 |
Beta blockers inhibit fetal thromboxane A2 production in vitro.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Platelets; Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Labetalol; Metoprolol; Pregnancy; Propranolol; Thromboxane A2 | 1988 |
Effects of propranolol and metoprolol on glucose, cyclic AMP and insulin responses during pharmacologic hyperglucagonemia in hemodialysis patients.
Topics: Adult; Blood Glucose; Cyclic AMP; Female; Glucagon; Gluconeogenesis; Humans; Hypoglycemia; Insulin; Liver; Liver Glycogen; Male; Metoprolol; Propranolol; Renal Dialysis | 1985 |
Evidence for beta adrenoceptors in proximal tubules. Isoproterenol-sensitive adenylate cyclase in pars recta of canine nephron.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dogs; Isoproterenol; Kidney Tubules, Proximal; Metoprolol; Nephrons; Norepinephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1985 |
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Disease; Cyclic AMP; Electrocardiography; Female; Heart Rate; Lactates; Male; Metoprolol; Phosphates; Phosphocreatine; Propranolol; Sotalol; Swine; Time Factors; Ventricular Fibrillation | 1986 |
Effects of beta non-selective and beta 1 selective adrenergic blocking agents on glucagon secretion from isolated perfused rat pancreas.
Topics: Animals; Arginine; Epinephrine; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Metoprolol; Models, Biological; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Characterization of functional beta-adrenoceptor subtypes in rabbit urinary bladder smooth muscle.
Topics: Animals; Butoxamine; Dobutamine; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Propranolol; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder | 1986 |
Evidence of beta-adrenergic involvement in forced swimming-induced behavioural despair of mice.
Topics: Animals; Atenolol; Behavior, Animal; Female; Imipramine; Immobilization; Isoproterenol; Male; Metoprolol; Mice; Physical Exertion; Propranolol; Receptors, Adrenergic, beta; Reserpine; Stress, Psychological; Swimming | 1987 |
Stimulatory effects of neuronally released norepinephrine on renin release in vitro.
Topics: Animals; Cations, Divalent; Denervation; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Metoprolol; Neurons; Nifedipine; Norepinephrine; Potassium; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Renin; Sympathetic Nervous System | 1988 |
Effects of thyroid hormone and beta-adrenoceptor blocking agents on urinary excretion of 3-methylhistidine and plasma amino acids in man.
Topics: Adult; Amino Acids; Female; Heart Rate; Histidine; Humans; Male; Methylhistidines; Metoprolol; Muscle Proteins; Propranolol; Triiodothyronine | 1986 |
The influence of antihypertensive drug therapy on renal transplant function and outcome.
Topics: Antihypertensive Agents; Clonidine; Creatinine; Cyclosporins; Graft Rejection; Humans; Kidney; Kidney Transplantation; Metoprolol; Nifedipine; Propranolol | 1988 |
Reactivity to mental stress and cold provocation during long-term treatment with metoprolol, propranolol or hydrochlorothiazide.
Topics: Adult; Blood Pressure; Catecholamines; Cold Temperature; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Propranolol; Psychological Tests; Stress, Psychological; Time Factors | 1986 |
Effect of hydralazine on the elimination of antipyrine in the rat.
Topics: Administration, Oral; Animals; Antipyrine; Biological Availability; Body Temperature; Drug Synergism; Hydralazine; Metoprolol; Propranolol; Rats; Rats, Inbred Strains | 1987 |
Synthesis and pharmacological activity of N-alkyl-1,2-diphenylethanolamines.
Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Ethanolamines; Jejunum; Male; Metoprolol; Muscle, Smooth, Vascular; Myocardial Contraction; Propranolol; Rabbits; Rats; Vas Deferens | 1987 |
Propranolol versus metoprolol in anxiety disorders.
Topics: Anxiety Disorders; Humans; Metoprolol; Propranolol | 1987 |
Rapid determination of the enantiomers of metoprolol, oxprenolol and propranolol in urine.
Topics: Biotransformation; Chromatography, Thin Layer; Humans; Indicators and Reagents; Metoprolol; Oxprenolol; Propranolol; Spectrometry, Fluorescence; Stereoisomerism | 1987 |
Increase of renal sympathetic nerve activity by metoprolol or propranolol in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Kidney; Male; Metoprolol; Pressoreceptors; Propranolol; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 1987 |
[Medical therapy of portal hypertension].
Topics: Atenolol; Cardiac Output; Humans; Hypertension, Portal; Metoprolol; Propranolol | 1986 |
Effects of thyroid hormone and beta-blocking agents on plasma amino acids in rats.
Topics: Amino Acids; Animals; Body Weight; Hyperthyroidism; Male; Metoprolol; Propranolol; Rats; Rats, Inbred Strains; Triiodothyronine | 1986 |
Combination headache: practical experience with a combination of a beta-blocker and an antidepressive.
Topics: Adult; Amitriptyline; Cluster Headache; Drug Therapy, Combination; Female; Headache; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Propranolol | 1986 |
Plasma levels of beta-blocking drugs prior to coronary artery bypass surgery.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Time Factors | 1985 |
Addition of nifedipine to maximal beta-blocker-nitrate therapy: effects on exercise capacity and global left ventricular performance at rest and during exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Isosorbide; Male; Metoprolol; Middle Aged; Nadolol; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Propranolol; Radionuclide Imaging; Rest | 1985 |
Kinetics of 1,2-dinitroglycerin following sustained release nitroglycerin: influence of propranolol and metoprolol.
Topics: Adult; Biotransformation; Delayed-Action Preparations; Drug Interactions; Humans; Kinetics; Metabolic Clearance Rate; Metoprolol; Nitroglycerin; Propranolol | 1985 |
Effects of propranolol on atherogenesis in the cholesterol-fed rabbit.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cholesterol Esters; Cholesterol, Dietary; Male; Metoprolol; Propranolol; Rabbits; Sodium Chloride; Sterol O-Acyltransferase; Subcellular Fractions | 1985 |
Metoprolol for intermittent explosive disorder.
Topics: Adult; Aggression; Anger; Carbamazepine; Humans; Male; Metoprolol; Neurocognitive Disorders; Propranolol; Rage; Violence | 1985 |
Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices.
Topics: Adenylyl Cyclases; Animals; Colforsin; Diterpenes; Electrophysiology; Hippocampus; Male; Metoprolol; Neurons, Afferent; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1985 |
Catecholamine secretion from the rabbit adrenal gland is not modulated by a mechanism involving beta-adrenoceptors.
Topics: Adrenal Glands; Animals; Catecholamines; Electric Stimulation; Epinephrine; Feedback; In Vitro Techniques; Isoproterenol; Metoprolol; Propranolol; Rabbits; Receptors, Adrenergic, beta; Splanchnic Nerves | 1984 |
Effects of neuropeptide Y (NPY) on mechanical activity and neurotransmission in the heart, vas deferens and urinary bladder of the guinea-pig.
Topics: Animals; Atropine; Electric Stimulation; Guanethidine; Guinea Pigs; Heart Atria; Male; Metoprolol; Muscle Contraction; Muscle Tonus; Nerve Tissue Proteins; Neuropeptide Y; Portal Vein; Propranolol; Synaptic Transmission; Trachea; Urinary Bladder; Vas Deferens | 1984 |
Pharmacological evidence for differences in the beta-adrenoreceptor populations mediating atrial and ventricular chronotropic responses in the unanaesthetized dog.
Topics: Alprenolol; Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Parasympatholytics; Propranolol; Receptors, Adrenergic, beta | 1984 |
Beta-blockers and changes in lipoprotein fractions.
Topics: Adrenergic beta-Antagonists; Cholesterol; Humans; Lipoproteins; Metoprolol; Propranolol | 1980 |
beta-Adrenoreceptor antagonists and the dysfunction of the blood-brain barrier induced by adrenaline.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood-Brain Barrier; Butoxamine; Epinephrine; Male; Metoprolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Metoprolol; Propranolol; Pupil; Rabbits; Sympathomimetics; Terbutaline; Timolol; Water | 1980 |
Metoprolol in essential tremor.
Topics: Dose-Response Relationship, Drug; Humans; Isoproterenol; Metoprolol; Propanolamines; Propranolol; Tremor | 1980 |
Insulin release and carbohydrate tolerance in hyperthyroid patients during non-selective or selective beta-1-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperthyroidism; Insulin; Insulin Secretion; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1980 |
Pre- and postjunctional beta-adrenoceptor mediated effects on transmitter release and effector response in the isolated rat portal vein.
Topics: Animals; Autacoids; Electric Stimulation; Female; Hypertension; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Portal Vein; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetrodotoxin; Vasoconstriction | 1980 |
Antihypertensive drugs that alter adrenergic function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System | 1980 |
Ocular penetration of beta-adrenergic blocking agents. An experimental study with atenolol, metoprolol, timolol and propranolol.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Atenolol; Carbon Radioisotopes; Ciliary Body; Cornea; Eye; Female; Iris; Male; Metoprolol; Nictitating Membrane; Propranolol; Rabbits; Timolol; Tritium | 1980 |
Acebutolol, metoprolol and propranolol in conscious dogs with chronic heart-block: chronotropic effects and relation between depression of ventricular activity and beta-adrenoceptor blocking potency.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Dogs; Female; Heart Block; Heart Rate; Male; Metoprolol; Propranolol | 1980 |
Beta blockers and COPD.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Animals; Humans; Lung Diseases, Obstructive; Metoprolol; Propranolol; Rats; Receptors, Adrenergic, beta | 1980 |
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions].
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol | 1980 |
[Cholinergic antagonism by beta-blockers. II. Sequence of interactions and final steady state effects].
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Drug Interactions; Guinea Pigs; Heart; Isoproterenol; Labetalol; Male; Metoprolol; Practolol; Propranolol; Receptors, Cholinergic; Time Factors | 1980 |
The effect of beta-receptor blockade on adrenaline-induced changes in redox and energy state in m. vastus lateralis and m. soleus of the rat in vivo.
Topics: Adenine Nucleotides; Adrenergic beta-Antagonists; Animals; Blood Glucose; Creatine; Energy Metabolism; Epinephrine; Female; Glycogen; Lactates; Metoprolol; Muscles; Oxidation-Reduction; Phosphates; Phosphocreatine; Propranolol; Pyruvates; Rats | 1980 |
Adaptation to prolonged beta-blockade of rabbit atrial, purkinje, and ventricular potentials, and of papillary muscle contraction. Time-course of development of and recovery from adaptation.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Electrocardiography; Electrophysiology; Female; Heart Atria; Heart Conduction System; Heart Ventricles; Male; Metoprolol; Muscle Contraction; Papillary Muscles; Propranolol; Purkinje Fibers; Rabbits; Time Factors | 1981 |
[Use of beta-adrenergic blocking agents in acute myocardial infarction (author's transl)].
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Coronary Circulation; Creatine Kinase; Electrocardiography; Hemodynamics; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol | 1981 |
Effects of selective and non-selective beta-adrenergic agents on insulin secretion in vivo.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Isoproterenol; Metoprolol; Mice; Propanolamines; Propranolol; Terbutaline; Thiazoles | 1981 |
[Serum lipid levels under chronical treatment with beta-receptor blocking agents in patients with coronary artery disease (author's transl)].
Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Cholesterol; Coronary Disease; Diabetes Mellitus; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Smoking; Triglycerides | 1981 |
Studies on the effect of alpha- and of beta-adrenergic blocking agents on the circulation in human limbs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cold Temperature; Hand; Hemodynamics; Humans; Indoramin; Intermittent Claudication; Leg; Male; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Regional Blood Flow; Vascular Diseases | 1980 |
Anticholinesterase effect of sotalol.
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase Inhibitors; In Vitro Techniques; Metoprolol; Muscle Contraction; Physostigmine; Practolol; Propranolol; Ranidae; Sotalol | 1981 |
Effect of inflammatory disease on plasma concentrations of three beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Proteins; Blood Sedimentation; Female; Humans; Inflammation; Liver; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol; Protein Binding | 1981 |
Interaction of cimetidine with metoprolol, propranolol, or atenolol.
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Interactions; Humans; Metoprolol; Propanolamines; Propranolol | 1981 |
Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Metoprolol; Propranolol; Sotalol; Vascular Resistance | 1981 |
The effect of beta, adrenergic blockade on serum potassium and glucose levels during open heart surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Glucose; Cardiac Surgical Procedures; Coronary Artery Bypass; Female; Humans; Male; Metoprolol; Middle Aged; Potassium; Propranolol | 1981 |
Drug-induced localized systemic scleroses.
Topics: Adrenergic beta-Antagonists; Humans; Methysergide; Metoprolol; Practolol; Propranolol; Scleroderma, Systemic | 1981 |
Variability in the preventive action of the B-blockers on genetic hypertension in the rat.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors | 1980 |
Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Female; Heart Rate; Humans; Male; Metoprolol; Propranolol; Prostaglandins E; Prostaglandins F; Renin; Thromboxane B2; Thromboxanes | 1982 |
Combined intravenous administration of diazoxide and beta-blocking agent in acute treatment of severe hypertension or hypertensive crisis.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Diazoxide; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Renin | 1982 |
Comparative investigation of the effects of metoprolol, propranolol, practolol, and verapamil in the acute phase of experimental myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Central Venous Pressure; Creatine Kinase; Hydrogen-Ion Concentration; Metoprolol; Myocardial Infarction; Practolol; Propanolamines; Propranolol; Rats; Verapamil | 1982 |
Effect of low-dose epinephrine infusion on hemodynamics after selective and nonselective beta-blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Drug Interactions; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Regional Blood Flow; Vascular Resistance | 1982 |
Beta-blockers after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Propranolol; Timolol | 1982 |
Studies on beta-adrenoceptor mediated facilitation of sympathetic neurotransmission.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Epinephrine; Hindlimb; Isoproterenol; Metoprolol; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction | 1981 |
Effects of cardioselective and nonselective beta-adrenergic antagonists on pulmonary mechanics.
Topics: Adrenergic beta-Antagonists; Adult; Humans; Lung; Lung Volume Measurements; Male; Metoprolol; Nadolol; Organ Specificity; Propanolamines; Propranolol; Pulmonary Ventilation | 1982 |
Non-invasive assessment of diastolic function in hypertrophic cardiomyopathy on and off beta adrenergic blocking drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Hypertrophic; Diastole; Female; Heart; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol | 1982 |
Relevance of selectivity and non-selectivity in beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Adult; Atropine; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Norepinephrine; Organ Specificity; Propranolol | 1982 |
Comparison of withdrawal phenomena after propranolol, metoprolol and pindolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Heart Rate; Humans; Metoprolol; Middle Aged; Pindolol; Propranolol; Substance Withdrawal Syndrome; Time Factors | 1982 |
Effects of beta-adrenoceptor agonists and antagonists in patients with peripheral autonomic neuropathy.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Albuterol; Amyloidosis; Autonomic Nervous System Diseases; Blood Pressure; Female; Heart Rate; Humans; Hypotension, Orthostatic; Isoproterenol; Male; Metoprolol; Middle Aged; Peripheral Nervous System Diseases; Pindolol; Posture; Propranolol | 1982 |
Managing angina with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Humans; Metoprolol; Nadolol; Nitrates; Propanolamines; Propranolol; Timolol | 1982 |
Low-dose beta blockade in the treatment of chronic cardiac failure.
Topics: Adrenergic beta-Antagonists; Adult; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propranolol | 1982 |
[Explosive diarrhea during treatment with beta blockers].
Topics: Adrenergic beta-Antagonists; Aged; Diarrhea; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol | 1982 |
[Therapy of essential tremor with special reference to the use of beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bupranolol; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Pindolol; Prognosis; Propranolol; Sotalol; Tremor | 1982 |
Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Cardiac Catheterization; Drug Interactions; Female; Humans; Hypertension; Hypotension; Male; Metoprolol; Myocardial Infarction; Practolol; Prenalterol; Propranolol | 1982 |
Secondary prevention after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Prognosis; Propranolol; Timolol | 1982 |
[Effect of acute beta 1 and beta 1/beta 2 receptor blockade on carbohydrate and lipid metabolism during exertion].
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Carbohydrates; Fatty Acids, Nonesterified; Heart Rate; Humans; Insulin; Lactates; Lipids; Metoprolol; Physical Exertion; Propranolol; Triglycerides | 1983 |
Haemodynamic dose-response effects of intravenous beta-blocking drugs with different ancillary properties in patients with coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Coronary Disease; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Pulmonary Wedge Pressure | 1982 |
Subclassification of human beta-adrenergic receptors mediating renin release.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Betaxolol; Dobutamine; Fenoterol; Humans; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin | 1983 |
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Atenolol; Coronary Circulation; Coronary Disease; Isoproterenol; Metoprolol; Perfusion; Phentolamine; Prazosin; Propranolol; Rats; Time Factors; Ventricular Fibrillation; Yohimbine | 1983 |
Possible significance of the pharmacological differentiation of beta-blocking agents in hemodynamic effects in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Carteolol; Hemodynamics; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 1983 |
The influence of vascular beta-adrenoceptors on the position and mobility of the rabbit incisor tooth.
Topics: Adrenergic beta-Antagonists; Animals; Electric Stimulation; Ephedrine; Female; Incisor; Isoproterenol; Male; Metoprolol; Periodontal Ligament; Propanolamines; Propranolol; Rabbits; Sympathetic Nervous System; Tooth Mobility; Vascular Resistance; Vasoconstriction | 1982 |
Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Humans; Hyperthyroidism; Metoprolol; Middle Aged; Propranolol; Sotalol; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Bradycardia; Coma; Dose-Response Relationship, Drug; Female; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol; Seizures | 1983 |
Hormonal effects of beta-receptor blockade during exercise.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Metoprolol; Physical Exertion; Prolactin; Propranolol; Pulse; Testosterone | 1983 |
[Peripheral vascular effects of metoprolol, pindolol and propranolol in hypertensive patients].
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Catecholamines; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Regional Blood Flow; Time Factors | 1983 |
[Secondary prevention of myocardial infarct with beta blockers].
Topics: Adrenergic beta-Antagonists; Coronary Circulation; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Propranolol; Recurrence | 1983 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucagon; Gluconeogenesis; Glycerol; Glycogen; Humans; Hypertension; Hypoglycemia; Insulin; Lactates; Lactic Acid; Liver; Metoprolol; Propranolol | 1983 |
Effect of beta-blocking drugs on red cell adhesive and rheological properties.
Topics: Adrenergic beta-Antagonists; Blood Viscosity; Cell Adhesion; Endothelium; Epinephrine; Erythrocytes; Humans; In Vitro Techniques; Metoprolol; Propranolol; Ultrafiltration | 1983 |
The ulcerogenic effect on the oesophagus of three beta-adrenoceptor antagonists, investigated in a new porcine oesophagus test model.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Esophageal Diseases; Esophagus; Female; Male; Metoprolol; Propranolol; Swine; Ulcer | 1983 |
Impairment of physical performance after treatment with beta blockers and alpha blockers.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running | 1984 |
Comparison of metoprolol and propranolol in the treatment of akathisia.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Blood Pressure; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Psychomotor Agitation; Respiratory Sounds | 1984 |
Beta-blockers in isoproterenol-enhanced essential tremor.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Isoproterenol; Metoprolol; Middle Aged; Propranolol; Timolol; Tremor | 1984 |
Polymorphic metabolism of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Biotransformation; Drug Interactions; Ethanolamines; Heart Rate; Humans; Metoprolol; Propranolol | 1984 |
Study of the influence of nifedipine on the pharmacokinetics and pharmacodynamics of propranolol, metoprolol and atenolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Drug Interactions; Humans; Kinetics; Male; Metoprolol; Nifedipine; Propranolol | 1984 |
Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Drug Interactions; Female; Half-Life; Heart Diseases; Heart Rate; Humans; Kinetics; Male; Metoprolol; Propranolol; Verapamil | 1984 |
The interaction between H2-receptor antagonists and beta-adrenoceptor blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Kinetics; Metoprolol; Penbutolol; Pindolol; Propranolol; Ranitidine | 1984 |
The effect of beta-adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin.
Topics: Adrenergic beta-Antagonists; Atenolol; Biological Availability; Drug Interactions; Humans; Kinetics; Male; Metoprolol; Propranolol; Warfarin | 1984 |
Beta-adrenoceptor blocker pharmacokinetics and the oral contraceptive pill.
Topics: Acebutolol; Adrenergic beta-Antagonists; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Female; Humans; Kinetics; Metoprolol; Oxprenolol; Propranolol; Time Factors | 1984 |
Beta-adrenergic antagonist inhibition of hepatic 3,5,3'-triiodothyronine production.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Dithiothreitol; Liver; Male; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Timolol; Triiodothyronine | 1984 |
Beta-adrenergic blockers. Choosing among them.
Topics: Adrenergic beta-Antagonists; Atenolol; Cardiovascular Diseases; Humans; Kinetics; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1984 |
Regulation of liver lipase. II. Involvement of the alpha 1-receptor.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cholesterol, HDL; Ether; Lipase; Liver; Male; Metoprolol; Norepinephrine; Prazosin; Propranolol; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Beta 2-adrenergic stimulation of androgen production by cultured mouse testicular interstitial cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Androgens; Animals; Cells, Cultured; Isoproterenol; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Metoprolol; Mice; Propanolamines; Propranolol | 1984 |
Effect of three beta-blockers with different pharmacological properties on metabolic, cardiovascular and hormonal response to insulin-induced hypoglycemia in normal subjects.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; C-Peptide; Carteolol; Glucagon; Growth Hormone; Hemodynamics; Humans; Hydrocortisone; Hypoglycemia; Insulin; Kinetics; Male; Metoprolol; Propranolol; Pulse | 1984 |
Failure of 'therapeutic' doses of beta-adrenoceptor antagonists to alter the disposition of tolbutamide and lignocaine.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Proteins; Drug Interactions; Female; Humans; Lidocaine; Male; Metoprolol; Oxidation-Reduction; Propranolol; Protein Binding; Tolbutamide | 1984 |
Beta 1- and beta 2-adrenoceptor-mediated secretion of amylase from incubated rat parotid gland.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amylases; Animals; Ephedrine; Female; Metoprolol; Norepinephrine; Parotid Gland; Practolol; Prenalterol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Terbutaline | 1984 |
[Evidence, in uremic man, of the role of beta 2 adrenergic receptors in the secretion of parathyroid hormone and calcitonin (author's transl)].
Topics: Adult; Calcitonin; Female; Heart Rate; Humans; Kidney Diseases; Male; Metoprolol; Parathyroid Hormone; Phosphates; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Uremia | 1980 |
Modulation by beta-adrenoreceptors of spontaneous contractions of rat urinary bladder.
Topics: Animals; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder | 1982 |
The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Hemodynamics; Humans; Insulin; Metoprolol; Physical Exertion; Propranolol; Receptors, Adrenergic, beta; Sympathetic Nervous System | 1983 |
Influence of beta-adrenoceptor blockade by metoprolol and propranolol on plasma concentrations and effects of noradrenaline and adrenaline during i.v. infusion.
Topics: Adult; Cyclic AMP; Epinephrine; Hemodynamics; Humans; Male; Metoprolol; Norepinephrine; Propranolol | 1983 |
Increased shock-induced fighting with supersensitive beta-adrenergic receptors.
Topics: Aggression; Animals; Brain; Cell Membrane; Electroshock; Haloperidol; Humans; Male; Metoprolol; Pindolol; Posture; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1983 |
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages | 1983 |
Propranolol enhances the effect of ACTH on plasma cortisol, but not on aldosterone in man.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Humans; Hydrocortisone; Male; Metoprolol; Middle Aged; Propranolol; Renin | 1983 |
Beta adrenoreceptors in the rabbit bladder detrusor muscle.
Topics: Animals; Ethanolamines; Iodine Radioisotopes; Iodocyanopindolol; Male; Metoprolol; Muscle, Smooth; Pindolol; Practolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Urinary Bladder | 1984 |
The identification and characterization of beta-adrenergic receptors in human amnion tissue.
Topics: Amnion; Binding, Competitive; Cyclic AMP; Ethanolamines; Female; Humans; Iodocyanopindolol; Isoproterenol; Metoprolol; Pindolol; Pregnancy; Propranolol; Receptors, Adrenergic, beta | 1984 |
Beta 1 - beta 2 blocking activity of propranolol and metoprolol in the unanaesthetized genetically hypertensive and normotensive rat.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Isoproterenol; Male; Metoprolol; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
The effect of beta-adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin after a single dose.
Topics: Adult; Atenolol; Drug Interactions; Factor VII; Heart Rate; Humans; Kinetics; Male; Metoprolol; Propranolol; Prothrombin Time; Receptors, Adrenergic, beta; Warfarin | 1984 |
Lack of influence of beta adrenergic blockade on serum potassium during an infusion of potassium.
Topics: Adult; Homeostasis; Humans; Infusions, Parenteral; Male; Metoprolol; Potassium; Propranolol; Receptors, Adrenergic, beta | 1984 |
Effects of metoprolol and propranolol on glucose tolerance and insulin secretion in diabetes mellitus.
Topics: Adult; Aged; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Glucose Tolerance Test; Heart Rate; Humans; Hypertension; Insulin; Insulin Secretion; Male; Metoprolol; Middle Aged; Propranolol; Random Allocation | 1984 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Nitroglycerin; Oxygen Consumption; Propranolol; Verapamil | 1984 |
Chronic propranolol treatment blunts right ventricular hypertrophy in rats at high altitude.
Topics: Adaptation, Physiological; Altitude; Animals; Cardiomegaly; Hypoxia; Male; Metoprolol; Polycythemia; Propranolol; Rats | 1980 |
Studies with long acting propranolol.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Delayed-Action Preparations; Half-Life; Heart Rate; Humans; Hypertension; Metoprolol; Oxprenolol; Physical Exertion; Propranolol | 1984 |
Effect of epinephrine on renal potassium excretion in the isolated perfused rat kidney.
Topics: Animals; Butoxamine; Epinephrine; Glomerular Filtration Rate; Isoproterenol; Kidney; Male; Metoprolol; Natriuresis; Perfusion; Potassium; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Urination | 1984 |
Diazepam, alpha and beta neurotransmission modifying drugs and contrast media mortality in mice.
Topics: Animals; Clonidine; Diatrizoate; Diatrizoate Meglumine; Diazepam; Drug Interactions; Female; Lethal Dose 50; Male; Metoprolol; Mice; Phentolamine; Prazosin; Propranolol; Sympatholytics; Sympathomimetics | 1984 |
Comparative effects of propranolol, timolol and metoprolol on myocardial infarct size after experimental coronary artery occlusion.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Fatty Acids, Nonesterified; Female; Heart Rate; Male; Metoprolol; Myocardial Infarction; Myocardium; Oxygen Consumption; Propranolol; Timolol | 1984 |
[Effect of metoprolol on water drinking activity in Wistar Kyoto rats].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Drinking; Heart Rate; Male; Metoprolol; Propranolol; Rats; Rats, Inbred WKY | 1984 |
Effects of the (+/-)-, (+)- and (-)-forms of propranolol, timolol and metoprolol on noradrenergic transmission in the rat isolated right ventricle.
Topics: Animals; Drug Interactions; Electric Stimulation; Heart Ventricles; In Vitro Techniques; Isomerism; Male; Metoprolol; Myocardial Contraction; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Stimulation, Chemical; Timolol; Tritium | 1984 |
Accumulation and adverse effects of metoprolol and propranolol after concurrent administration of cimetidine.
Topics: Adult; Blood Pressure; Cimetidine; Drug Interactions; Heart Rate; Humans; Kinetics; Male; Metoprolol; Physical Exertion; Propranolol | 1983 |
Comparison of metoprolol and propranolol in the treatment of lithium tremor.
Topics: Humans; Lithium; Metoprolol; Propranolol; Tremor | 1984 |
Effects of anti-hypertensive therapy on serum lipoproteins. Treatment with metoprolol, propranolol and hydrochlorothiazide.
Topics: Adipose Tissue; Apolipoproteins; Blood Glucose; Catecholamines; Fatty Acids; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoprotein Lipase; Lipoproteins; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1983 |
Effect of adrenergic stimulation and blockade on ventricular defibrillation in the rat.
Topics: Albuterol; Animals; Atropine; Isoproterenol; Male; Metoprolol; Norepinephrine; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Sympathomimetics; Time Factors; Ventricular Fibrillation | 1983 |
Interaction between norepinephrine and hypoxia on carotid body chemoreception in rabbits.
Topics: Animals; Carotid Body; Chemoreceptor Cells; Female; Hypoxia; Male; Metoprolol; Norepinephrine; Propranolol; Rabbits | 1983 |
Cardioprotective effects of increased myocardial glycogen stores and beta-blockers in cardiac surgery.
Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Creatine Kinase; Female; Glycogen; Heart Arrest, Induced; Heart Valve Diseases; Humans; Isoenzymes; Male; Metoprolol; Myocardium; Propranolol | 1983 |
Effects of three bradycardiac drugs on regional myocardial blood flow and function in areas distal to a total or partial coronary occlusion in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Collateral Circulation; Coronary Circulation; Coronary Disease; Depression, Chemical; Dogs; Female; Heart Rate; Male; Metoprolol; Propranolol; Sotalol | 1984 |
Selective and nonselective beta-blockade of the peripheral circulation.
Topics: Adult; Blood Circulation; Blood Pressure; Heart Rate; Humans; Leg; Male; Metoprolol; Physical Exertion; Propranolol; Random Allocation; Vascular Resistance | 1984 |
Metoprolol compared with propranolol in the treatment of essential tremor.
Topics: Adult; Aged; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Tremor | 1984 |
The influence of propranolol, metoprolol, and mepindolol on mucociliary clearance in coronary heart disease patients without pulmonary disease.
Topics: Cilia; Coronary Disease; Female; Humans; Lung; Lung Diseases; Male; Metoprolol; Middle Aged; Mucous Membrane; Pindolol; Propranolol | 1984 |
Electrophysiologic effects of intravenous metoprolol.
Topics: Adult; Arrhythmias, Cardiac; Atrioventricular Node; Electrocardiography; Female; Heart Conduction System; Humans; Infusions, Parenteral; Male; Metoprolol; Middle Aged; Propranolol | 1984 |
Increase in coagulation factor VIII activity in man following acute hypoglycaemia: mediation via an adrenergic mechanism.
Topics: Acute Disease; Adult; Blood Coagulation; Factor VIII; Female; Humans; Hypoglycemia; Male; Metoprolol; Propranolol; Sympathectomy | 1980 |
Ventilatory response to hypercapnia in normal subjects after propranolol, metoprolol and oxprenolol.
Topics: Adult; Carbon Dioxide; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypercapnia; Male; Maximal Expiratory Flow Rate; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Respiration | 1980 |
Prinzmetal's variant angina.
Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Diagnosis, Differential; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Propranolol; Verapamil | 1981 |
Hormonal and substrate responses during recovery from hypoglycaemia in man during beta 1-selective and non-selective beta-adrenergic blockade.
Topics: Acetoacetates; Adult; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Lactates; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1981 |
Lidocaine elimination: effects of metoprolol and of propranolol.
Topics: Adult; Chromatography, Gas; Drug Interactions; Heart Rate; Humans; Kinetics; Lidocaine; Male; Metoprolol; Propanolamines; Propranolol | 1983 |
Beta-blockade in the hyperventilation syndrome. A retrospective assessment of symptoms and complaints.
Topics: Adult; Female; Humans; Hyperventilation; Male; Metoprolol; Middle Aged; Outcome and Process Assessment, Health Care; Propanolamines; Propranolol; Retrospective Studies; Surveys and Questionnaires | 1983 |
Effect of beta-adrenergic agonists on apnea reflexes in newborn lambs.
Topics: Albuterol; Animals; Animals, Newborn; Apnea; Blood Circulation; Blood Pressure; Electric Stimulation; Fenoterol; Heart Rate; Laryngeal Nerves; Metoprolol; Propranolol; Reflex; Respiratory Center; Sheep; Terbutaline; Vascular Resistance | 1983 |
[Effects of propranolol and metoprolol on peripheral circulation in intermittent claudication].
Topics: Aged; Humans; Hypertension; Intermittent Claudication; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1983 |
The interaction of cimetidine with metoprolol, atenolol, propranolol, pindolol and penbutolol.
Topics: Atenolol; Biological Availability; Cimetidine; Drug Interactions; Guanidines; Humans; Metoprolol; Penbutolol; Pindolol; Propanolamines; Propranolol | 1983 |
Successful treatment of supraventricular tachycardia with metoprolol, a cardioselective beta blocker.
Topics: Bronchial Spasm; Digoxin; Drug Therapy, Combination; Female; Humans; Infant; Metoprolol; Propanolamines; Propranolol; Sleep Wake Disorders; Tachycardia, Paroxysmal | 1983 |
Antihypertensive treatment inhibiting the progression of diabetic nephropathy.
Topics: Adult; Blood Pressure; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Hypertension; Male; Metoprolol; Propanolamines; Propranolol | 1980 |
Atenolol in hypertension: follow-up of patients crossed over to this agent from propranolol, pindolol or metoprolol.
Topics: Adult; Aged; Atenolol; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Metoprolol; Middle Aged; Pindolol; Propanolamines; Propranolol | 1980 |
Central pre- and postsynaptic monoamine receptors in antidepressant therapy.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Catecholamines; Iontophoresis; Male; Metoprolol; Neurons; Propranolol; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Sotalol; Synapses | 1981 |
Plasma catecholamines and cardiovascular responses to hypoglycemia in hyperthyroidism before and during treatment with metoprolol or propranolol.
Topics: Adult; Epinephrine; Female; Goiter; Heart Rate; Humans; Hyperthyroidism; Hypoglycemia; Insulin; Kinetics; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Propranolol; Reference Values; Thyroid Gland; Thyroxine; Triiodothyronine | 1980 |
An in vitro assessment of cellular and humoral immune function in pulmonary tuberculosis: correction of defective neutrophil motility by ascorbate, levamisole, metoprolol and propranolol.
Topics: Antibody Formation; Ascorbic Acid; Chemotaxis, Leukocyte; Humans; Immunity, Cellular; Immunoglobulin A, Secretory; Immunoglobulins; Leukocyte Migration-Inhibitory Factors; Levamisole; Lymphocytes; Metoprolol; Neutrophils; Propanolamines; Propranolol; Tuberculosis, Pulmonary | 1980 |
Effect of low-level renal nerve stimulation on renin release from nonfiltering kidneys.
Topics: Animals; Aortic Diseases; Constriction, Pathologic; Dogs; Female; Filtration; Kidney; Male; Metoprolol; Nerve Block; Neural Inhibition; Propranolol; Renin | 1981 |
Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Verapamil | 1982 |
Influence of hyperthyroidism on the kinetics of methimazole, propranolol, metoprolol and atenolol.
Topics: Administration, Oral; Atenolol; Female; Humans; Hyperthyroidism; Kinetics; Male; Metabolic Clearance Rate; Methimazole; Metoprolol; Middle Aged; Propanolamines; Propranolol | 1982 |
High-performance liquid chromatographic method for the quantitative analysis of the aryloxypropanolamines propranolol, metoprolol and atenolol in plasma and tissue.
Topics: Animals; Atenolol; Brain Chemistry; Chromatography, High Pressure Liquid; Male; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Selective and non-selective beta-blockers: are both effective in prophylaxis of migraine? A clinical trial versus methysergide.
Topics: Adolescent; Adult; Female; Humans; Male; Methysergide; Metoprolol; Middle Aged; Migraine Disorders; Propanolamines; Propranolol | 1982 |
Beta blockade and physical training in rats.
Topics: Animals; Blood Pressure; Body Temperature Regulation; Body Weight; Heart Rate; Metoprolol; Physical Conditioning, Animal; Propanolamines; Propranolol; Rats | 1982 |
Interaction of metoprolol, propranolol and atenolol with concurrent administration of cimetidine.
Topics: Adult; Atenolol; Cimetidine; Drug Interactions; Guanidines; Humans; Kinetics; Male; Metoprolol; Propanolamines; Propranolol | 1982 |
[Selective beta blockaders (metoprolol) versus non selective (propranolol): comparative effects on the composition of lipoprotein fractions and on blood pressure].
Topics: Blood Pressure; Cholesterol; Double-Blind Method; Female; Humans; Hyperlipidemias; Hypertension; Lipoproteins; Male; Metoprolol; Propanolamines; Propranolol; Triglycerides | 1980 |
Separation of enantiomeric amines by ion-pair chromatography.
Topics: Alprenolol; Chromatography, High Pressure Liquid; Metoprolol; Propanolamines; Propranolol | 1981 |
Influence of non-selective and selective beta adrenoceptor blockade on isoxsuprine-dependent hemodynamic and rheologic changes.
Topics: Adult; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Isoxsuprine; Male; Metoprolol; Propanolamines; Propranolol; Tachycardia | 1981 |
[Metoprolol in angina pectoris].
Topics: Aged; Angina Pectoris; Double-Blind Method; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Random Allocation | 1981 |
Comparative antihypertensive effects of propranolol and metoprolol in DOC-treated rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Heart Rate; Hypertension; Male; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Effect of propranolol and metoprolol on parathyroid hormone and calcitonin secretions in uraemic patients.
Topics: Adult; Calcitonin; Female; Heart Rate; Humans; Male; Metoprolol; Parathyroid Hormone; Propanolamines; Propranolol; Uremia | 1980 |
Effects of metoprolol and propranolol on theophylline elimination.
Topics: Adult; Humans; Male; Metabolic Clearance Rate; Metoprolol; Propanolamines; Propranolol; Smoking; Theophylline | 1980 |
[Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)].
Topics: Administration, Oral; Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Propranolol | 1980 |
Evidences supporting an increased sympathetic tone and reactivity in a subgroup of patients with essential hypertension.
Topics: Adult; Aging; Blood Pressure; Catecholamines; Diagnosis, Differential; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Norepinephrine; Posture; Propranolol; Sympathetic Nervous System | 1980 |
Non-autonomic component in bradycardia of endurance trained men at rest and during exercise.
Topics: Adult; Atropine; Autonomic Nerve Block; Blood Pressure; Heart Rate; Humans; Male; Metoprolol; Oxygen Consumption; Physical Endurance; Physical Exertion; Propranolol | 1980 |
beta-Adrenoreceptor-blocking agents and the blood-brain barrier.
Topics: Atenolol; Blood-Brain Barrier; Brain; Humans; Kinetics; Metoprolol; Propanolamines; Propranolol | 1980 |
Endothelial prostacyclin production, synergistic effect between adrenergic stimulating and blocking drugs.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adrenergic Agonists; Adrenergic Antagonists; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Epoprostenol; Humans; Isoproterenol; Metoprolol; Propranolol; Umbilical Veins | 1994 |
Plasma catecholamines and cyclic AMP response during head-up tilt test in patients with neurocardiogenic (vasodepressor) syncope.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Cyclic AMP; Female; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Norepinephrine; Posture; Propranolol; Syncope; Vasoconstriction | 1995 |
The effects of antianginal drugs on energy expenditure during exercise in normal subjects.
Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Energy Metabolism; Ethanolamines; Exercise; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Nicardipine; Propranolol | 1995 |
Enantioselective assay of beta-receptor antagonists present in microdialysis and plasma samples of rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Chromatography, High Pressure Liquid; Metoprolol; Microdialysis; Propranolol; Rats; Spectrometry, Fluorescence; Stereoisomerism | 1995 |
[Drug therapy of angina pectoris. Are the possibilities exploited well enough?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Propranolol; Retrospective Studies; Timolol | 1995 |
[Beta-receptor blockers after revascularization in coronary sclerosis].
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Disease; Humans; Male; Metoprolol; Multicenter Studies as Topic; Myocardial Infarction; Propranolol; Recurrence; Time Factors; Timolol | 1995 |
Beta 1-adrenergic mechanism is involved in stress-induced increase in arousal.
Topics: Animals; Arousal; Atropine; Butoxamine; Corticotropin-Releasing Hormone; Hypothalamus; Male; Metoprolol; Pentobarbital; Phentolamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Restraint, Physical; Sleep; Sleep Initiation and Maintenance Disorders; Stress, Physiological | 1994 |
Characterization of a phosphatidic acid phosphatase from rat brain cell membranes.
Topics: Adrenergic beta-Antagonists; Animals; Brain; Cations; Cell Membrane; Detergents; Hydrogen-Ion Concentration; Metoprolol; Octoxynol; Phosphatidate Phosphatase; Propranolol; Rats | 1994 |
[The correction of the hemodynamic disorders in patients with IHD complicated by intraventricular blocks by using beta-adrenergic agents].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Bundle-Branch Block; Drug Evaluation; Female; Hemodynamics; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propranolol; Time Factors | 1995 |
Demonstration of an in vivo functional beta 3-adrenoceptor in man.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Animals; Body Temperature Regulation; Cells, Cultured; Dobutamine; Female; Humans; Isoproterenol; Kinetics; Lipolysis; Male; Mammals; Metoprolol; Microdialysis; Middle Aged; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Regional Blood Flow; Terbutaline; Time Factors | 1995 |
Peripheral beta adrenergic blockade modifies airpuff startle-induced heart rate responses.
Topics: Adrenergic beta-Antagonists; Air; Animals; Celiprolol; Heart Rate; Metoprolol; Parasympathetic Nervous System; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex, Startle | 1995 |
Beta 2- but not beta 1-adrenoceptors are involved in desipramine enhancement of aggressive behavior in long-term isolated mice.
Topics: Aggression; Animals; Clenbuterol; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Social Isolation | 1994 |
Interactive and discontinuous long-lasting potentiation in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Metoprolol; Propranolol; Rats; Rats, Wistar; Sincalide | 1994 |
Vascular relaxing mechanism of denopamine in isolated canine coronary, femoral, mesenteric, and renal arteries.
Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Coronary Vessels; Dinoprost; Dogs; Ethanolamines; Female; Femoral Artery; In Vitro Techniques; Male; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Propranolol; Renal Artery; Vasodilator Agents | 1993 |
Effects of beta-adrenoceptor antagonists on portal vein hypertension and ethanol-induced gastric mucosal damage in rats.
Topics: Adrenergic beta-Antagonists; Animals; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; Labetalol; Male; Metoprolol; Nadolol; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1994 |
[Protection by blockers against human low density lipoprotein peroxidation induced by oxygen free radicals].
Topics: Acebutolol; Adrenergic beta-Antagonists; Free Radicals; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Malondialdehyde; Metoprolol; Propranolol | 1994 |
Toxicity of beta-blockers in a rat whole embryo culture: concentration-response relationships and tissue concentrations.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; In Vitro Techniques; Metoprolol; Pindolol; Propranolol; Rats; Rats, Wistar | 1994 |
Cardiac angiotensin II receptor populations during aortocaval fistulae, AII and beta adrenergic receptor blockade.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Cell Membrane; Down-Regulation; Heart; Kinetics; Male; Metoprolol; Myocardium; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin; Up-Regulation; Vena Cava, Inferior | 1994 |
The effects of tyramine on salivary flow rate and protein secretion by rat submandibular glands.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Isoelectric Focusing; Male; Metoprolol; Phenoxybenzamine; Prazosin; Propanolamines; Propranolol; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Saliva; Salivary Proteins and Peptides; Salivation; Secretory Rate; Serine Endopeptidases; Stimulation, Chemical; Submandibular Gland; Tyramine; Yohimbine | 1993 |
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes | 1993 |
Effects of adrenergic agonists and antagonists on the metabolism of [1-14C]oleic acid by rat hepatocytes.
Topics: Animals; Carbon Radioisotopes; Cholesterol Esters; Epinephrine; Ketone Bodies; Liver; Male; Metoprolol; Norepinephrine; Oleic Acid; Oleic Acids; Phentolamine; Phospholipids; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Triglycerides | 1993 |
Renal selective N-acetyl-L-gamma-glutamyl prodrugs: studies on the selectivity of some model prodrugs.
Topics: Ampyrone; Aniline Compounds; Animals; In Vitro Techniques; Kidney; Male; Metoprolol; Phenylacetates; Prodrugs; Propranolol; Rats; Rats, Wistar; Sulfadimethoxine; Sulfamethoxazole; Tissue Distribution | 1993 |
Simultaneous determination of propranolol or metoprolol in the presence of butyrophenones in human plasma by gas chromatography with mass spectrometry.
Topics: Butyrophenones; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Metoprolol; Propranolol | 1993 |
Beta-blocker treatment of idiopathic and ischemic dilated cardiomyopathy in patients with ejection fractions < or = 20%.
Topics: Aged; Cardiomyopathy, Dilated; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Stroke Volume; Treatment Outcome | 1993 |
Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy.
Topics: Cardiotonic Agents; Drug Interactions; Drug Stability; Heparin; Humans; Lidocaine; Metoprolol; Morphine; Nitroglycerin; Plasminogen Activators; Propranolol; Tissue Plasminogen Activator | 1995 |
Relative toxicity of beta blockers in overdose.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child, Preschool; Databases, Factual; Drug Overdose; Female; Humans; Infant; Male; Metoprolol; Middle Aged; Pindolol; Propranolol; Prospective Studies; Seizures; Sotalol | 1996 |
Effects of beta-blockers on HMG CoA reductase and LDL receptor activity in cultured human skin fibroblasts.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Betaxolol; Cells, Cultured; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, LDL; Male; Metoprolol; Propranolol; Receptors, LDL | 1996 |
Antihypertensive drugs reduce noradrenaline-induced hypertrophy of cultured myocardial cells.
Topics: Animals; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Felodipine; Heart; Leucine; Metoprolol; Myocardium; Norepinephrine; Propranolol; Protein Biosynthesis; Rats | 1996 |
Acute effects of beta 1-selective and nonselective beta-adrenergic receptor blockade on cardiac sympathetic activity in congestive heart failure.
Topics: Adrenergic beta-Antagonists; Epinephrine; Heart Conduction System; Heart Failure; Hemodynamics; Humans; Kinetics; Metoprolol; Middle Aged; Norepinephrine; Propranolol; Sympathetic Nervous System; Time Factors | 1996 |
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Asparagine; Binding Sites; CHO Cells; Computer Simulation; Cricetinae; Humans; Isoproterenol; Metoprolol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Propranolol; Receptors, Adrenergic, beta-2; Serine; Signal Transduction; Stereoisomerism | 1996 |
Xerostomia: prevalence and pharmacotherapy. With special reference to beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Amylases; Antihypertensive Agents; Atenolol; Comorbidity; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Placebos; Polypharmacy; Prevalence; Propranolol; Saliva; Salivary Proteins and Peptides; Secretory Rate; Sex Factors; Surveys and Questionnaires; Sweden; Xerostomia | 1996 |
Central propranolol and pindolol, but not atenolol nor metoprolol, inhibit sexual behavior in male rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Brain; Copulation; Ejaculation; Injections, Intraventricular; Male; Metoprolol; Pindolol; Propranolol; Rats; Sexual Behavior, Animal | 1996 |
A mechanistic study of beta-adrenoceptor antagonists on ethanol-induced gastric damage.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Central Nervous System Depressants; Dinoprostone; Ethanol; Gastric Mucosa; Leukocyte Count; Lipid Peroxides; Male; Malondialdehyde; Metoprolol; Peroxidase; Propranolol; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1996 |
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Ascorbic Acid; Calcium Channel Blockers; Carbazoles; Carvedilol; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Metoprolol; Nicardipine; Prazosin; Probucol; Propanolamines; Propranolol; Umbilical Veins | 1997 |
Role of central nicotinic and beta-adrenergic receptors in the onset and further development of tail-tremor induced by repeated nicotine administration to rats.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Animals; Carteolol; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Injections, Intraperitoneal; Injections, Spinal; Injections, Subcutaneous; Male; Mecamylamine; Metoprolol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxidopamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Nicotinic; Tail; Tremor | 1997 |
Catecholamines, catecholamine receptors, cell adhesion molecules, and acute stressor-related changes in cellular immunity.
Topics: Animals; Catecholamines; Cell Adhesion Molecules; Humans; Immunity, Cellular; Metoprolol; Physical Exertion; Propranolol; Receptors, Catecholamine; Stress, Physiological; T-Lymphocytes | 1998 |
The effects of beta-adrenoceptor antagonists on a rat model of neuroleptic-induced akathisia.
Topics: Adrenergic beta-Antagonists; Akathisia, Drug-Induced; Animals; Antipsychotic Agents; Arousal; Catalepsy; Defecation; Emotions; Haloperidol; Male; Metoprolol; Motor Activity; Nadolol; Propranolol; Rats; Rats, Wistar; Reaction Time | 1997 |
Effects of beta-adrenoceptor blockade on beta-adrenergic signal transduction in cardiomyopathic hamster (BIO 8262) hearts.
Topics: 5'-Nucleotidase; Adenylyl Cyclases; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Cricetinae; Heart Ventricles; Mesocricetus; Metoprolol; Myocardium; Organ Size; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction | 1997 |
Enantiomeric separation and sensitive detection of propranolol, metoprolol and atenolol derivatized with a fluorogenic reagent, 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulf onyl-2,1, 3-benzoxadiazole (DBD-COCl), on cellulose chiral colum
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, Gel; Chromatography, High Pressure Liquid; Indicators and Reagents; Metoprolol; Oxadiazoles; Propanolamines; Propranolol; Stereoisomerism | 1997 |
Effects of some beta-adrenergic blockers on male fertility parameters in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Fertility; Genitalia, Male; Male; Metoprolol; Organ Size; Propranolol; Rats; Sperm Head; Sperm Motility; Sperm Tail | 1998 |
Mechanisms of hemodynamic responses to cocaine in conscious rats.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channels; Calcium Channels, L-Type; Cocaine; Enzyme Inhibitors; Hemodynamics; Male; Metoprolol; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1998 |
Influence of chronic exposure to high concentrations of D-glucose and long-term beta-blocker treatment on intracellular calcium concentrations of porcine aortic endothelial cells.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Celiprolol; Cells, Cultured; Cohort Studies; Drug Synergism; Endothelium, Vascular; Glucose; Intracellular Fluid; Metoprolol; Propranolol; Swine; Time Factors | 1998 |
[Treatment of migraine attacks and migraine prophylaxis: recommendations of the German Migraine and Headache Society].
Topics: Adult; Analgesics; Antiemetics; Child; Clinical Protocols; Germany; Humans; Metoprolol; Migraine Disorders; Prevalence; Propranolol; Societies, Medical; Sumatriptan | 1998 |
Effects of antihypertensive drugs on cholesterol metabolism of human mononuclear leukocytes and hepatoma cells.
Topics: Antihypertensive Agents; Carcinoma, Hepatocellular; Cholesterol; Diltiazem; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Metoprolol; Nifedipine; Propranolol; Tumor Cells, Cultured; Verapamil | 1998 |
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.
Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol | 1998 |
Error structure for the HPLC analysis for atenolol, metoprolol and propranolol: a useful weighting method in parameter estimation.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Metoprolol; Propranolol; Reproducibility of Results | 1998 |
[Antioxidant effect of drugs used in cardiovascular therapy].
Topics: Adrenergic beta-Antagonists; Antioxidants; Ascorbic Acid; Atenolol; Calcium Channel Blockers; Copper; Female; Fluorescence; Humans; Lipid Peroxidation; Male; Metoprolol; Nifedipine; Pindolol; Propranolol | 1998 |
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol | 1998 |
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Carbazoles; Carvedilol; Heart Rate; Male; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Peroxidase; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Solubility; Ventricular Function, Left; Ventricular Pressure | 1998 |
Concentration-effect relationship of l-propranolol and metoprolol in spontaneous hypertensive rats after exercise-induced tachycardia.
Topics: Adrenergic beta-Antagonists; Animals; Blood Proteins; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Metoprolol; Physical Conditioning, Animal; Propranolol; Protein Binding; Rats; Rats, Inbred SHR | 1998 |
Study of propranolol and its related adrenoceptor antagonists on changes of gastric electrical parameters induced by ethanol in rats.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Ethanol; Gastric Mucosa; Labetalol; Male; Metoprolol; Nadolol; Propranolol; Rats; Rats, Sprague-Dawley | 1999 |
Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic beta-Antagonists; Celiprolol; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Endothelium, Vascular; Humans; Metoprolol; Propanolamines; Propranolol; Protein Precursors; RNA, Messenger; Thrombin | 1999 |
Sympathotropic drugs and the distribution of 99mTc-hydroxymethylene diphosphonate. Experimental studies in the mouse.
Topics: Adrenergic beta-Antagonists; Animals; Bone and Bones; Contrast Media; Ephedrine; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Radionuclide Imaging; Sotalol; Sympathomimetics; Technetium Tc 99m Medronate; Terbutaline; Tissue Distribution | 1999 |
Nonselective beta blockade attenuates the recruitment of CD62L(-)T lymphocytes following exercise.
Topics: Adrenergic beta-Antagonists; Adult; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Exercise; Humans; L-Selectin; Lymphocyte Count; Male; Metoprolol; Middle Aged; Propranolol; T-Lymphocytes | 1999 |
Synergistic interaction of catecholamine hormones and Mycobacterium avium results in the induction of interleukin-10 mRNA expression by murine peritoneal macrophages.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antigens, Bacterial; Bucladesine; Cyclic AMP; Dobutamine; Drug Synergism; Epinephrine; Gene Expression; Interleukin-10; Macrophages, Peritoneal; Male; Metoprolol; Mice; Mice, Inbred BALB C; Mycobacterium avium; Phentolamine; Propanolamines; Propranolol; RNA, Messenger; Terbutaline | 1999 |
Mitchell B. Balter Award--1998. Pindolol and major affective disorders: a three-year follow-up study of 30,485 patients.
Topics: Adrenergic beta-Antagonists; Atenolol; Depressive Disorder, Major; Disability Evaluation; Drug Therapy, Combination; Follow-Up Studies; Humans; Long-Term Care; Metoprolol; Pindolol; Propranolol; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1999 |
Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Confidence Intervals; Databases as Topic; Diuretics; Drug Compounding; Evaluation Studies as Topic; Female; Humans; Hydrochlorothiazide; Logistic Models; Male; Metolazone; Metoprolol; Myocardial Infarction; Odds Ratio; Ontario; Propranolol; Retrospective Studies; Sex Factors; Sodium Chloride Symporter Inhibitors; Timolol | 1999 |
Long-term follow-up of patients with long-QT syndrome treated with beta-blockers and continuous pacing.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child; Child, Preschool; Cohort Studies; Death, Sudden; Electric Countershock; Female; Follow-Up Studies; Humans; Incidence; Infant; Infant, Newborn; Long QT Syndrome; Male; Metoprolol; Middle Aged; Nadolol; Pacemaker, Artificial; Prognosis; Propranolol; Risk Assessment; Survival Analysis; Treatment Outcome | 1999 |
Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Enzyme Inhibitors; Kinetics; Ligands; Metoprolol; Mutagenesis, Site-Directed; Oxidation-Reduction; Propranolol; Quinidine; Quinine; Serine; Substrate Specificity; Yeasts | 2000 |
Interaction of alpha-melanotropin (alpha-MSH) and noradrenaline in the median eminence in the control of female sexual behavior.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; alpha-MSH; Animals; Dopamine; Female; Male; Median Eminence; Metoprolol; Norepinephrine; Ovariectomy; Posture; Prazosin; Propranolol; Rats; Rats, Wistar; Sexual Behavior, Animal | 2000 |
The role of beta-adrenergic receptors in the cutaneous water evaporation mechanism in the heat-acclimated pigeon (Columba livia).
Topics: Acclimatization; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Body Water; Columbidae; Hot Temperature; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Skin | 2000 |
Adrenoceptors in normal and malignant human melanocytes.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Idazoxan; Melanocytes; Metoprolol; Oxathiins; Propanolamines; Propranolol; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine | 2000 |
Role of P-glycoprotein in restricting propranolol transport in cultured rabbit conjunctival epithelial cell layers.
Topics: Adrenergic beta-Antagonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Conjunctiva; Epithelial Cells; Immunohistochemistry; Metoprolol; Propranolol; Rabbits | 2000 |
Beta-blockade in adriamycin-induced cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardiomyopathy, Dilated; Carvedilol; Doxorubicin; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Neoplasms; Propanolamines; Propranolol; Retrospective Studies; Stroke Volume | 2000 |
Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases.
Topics: 2,4-Dichlorophenoxyacetic Acid; Anesthetics, Local; Anti-Bacterial Agents; Bupivacaine; Chromatography, Liquid; Coumarins; Evaluation Studies as Topic; Ketoprofen; Metoprolol; Propranolol; Reagent Kits, Diagnostic; Ristocetin; Stereoisomerism; Thalidomide; Warfarin | 2000 |
Selective or nonselective beta-adrenergic blockade in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Heart Failure; Hemodynamics; Humans; Metoprolol; Prognosis; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction | 2000 |
Characterization of beta-adrenoceptors responsible for venom production in the venom gland of the snake Bothrops jararaca.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Bothrops; Crotalid Venoms; Cyclic AMP; Dioxoles; Ethanolamines; Exocrine Glands; Female; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Membranes; Metoprolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2000 |
Establishment and characterization of steroidogenic granulosa cells expressing beta(2)-adrenergic receptor: regulation of adrenodoxin and steroidogenic acute regulatory protein by adrenergic agents.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenodoxin; Animals; Blotting, Western; Cell Line, Transformed; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Follicle Stimulating Hormone; Genes, ras; Granulosa Cells; Immunohistochemistry; Isoproterenol; Metoprolol; Phosphodiesterase Inhibitors; Phosphoproteins; Plasmids; Progesterone; Propranolol; Rats; Receptors, Adrenergic, beta-2; Simian virus 40; Transfection | 2000 |
AAS and spectrophotometric determination of propranolol HCl and metoprolol tartrate.
Topics: Adrenergic beta-Antagonists; Metoprolol; Pharmaceutical Preparations; Propranolol; Spectrophotometry, Atomic | 2000 |
[Effect of migraine medications on monocyte chemotaxis] .
Topics: Adult; Analgesics; Aspirin; Chemotaxis, Leukocyte; Dihydroergotamine; Humans; Immune Tolerance; Male; Metoclopramide; Metoprolol; Migraine Disorders; Propranolol; Sumatriptan | 2000 |
Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells.
Topics: Adrenergic beta-Antagonists; Apoptosis; Becaplermin; Benzopyrans; Bisoprolol; Cell Culture Techniques; Cell Division; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Endothelium, Vascular; Ethanolamines; Gene Expression; Humans; In Situ Hybridization; Male; Metoprolol; Muscle, Smooth, Vascular; Nebivolol; Nitric Oxide; Platelet-Derived Growth Factor; Propranolol; Protein Precursors; Proto-Oncogene Proteins c-sis; RNA, Messenger; Transforming Growth Factor beta | 2001 |
[In vitro permeability studies as a substitute for in vivo studies--which requirements have to be met?].
Topics: Animal Testing Alternatives; Atenolol; Cell Culture Techniques; Cell Line; Cell Membrane Permeability; Humans; Intestinal Mucosa; Metoprolol; Propranolol; Quality Control; Reproducibility of Results; Tumor Cells, Cultured | 2001 |
Comparative effects of three beta blockers (atenolol, metoprolol, and propranolol) on survival after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Baltimore; Female; Humans; Male; Medical Records; Metoprolol; Myocardial Infarction; Outcome Assessment, Health Care; Patient Discharge; Proportional Hazards Models; Propranolol; Retrospective Studies; Survival Analysis | 2001 |
Are all beta-blockers equally effective in reducing mortality after acute myocardial infarction (AMI)?
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Drug Costs; Evidence-Based Medicine; Female; Humans; Male; Metoprolol; Myocardial Infarction; Propranolol; Research Design; Survival Analysis; Treatment Outcome | 2001 |
Bucindolol exerts agonistic activity on the propranolol-insensitive state of beta1-adrenoceptors in human myocardium.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Atrial Function, Right; Benzopyrans; Ethanolamines; Female; Heart; Humans; In Vitro Techniques; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Papillary Muscles; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Ventricular Function, Left | 2002 |
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardiac Catheterization; Carvedilol; Coronary Disease; Coronary Stenosis; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Hemodynamics; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Quinazolines; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stroke Volume; Survival Rate; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid | 2002 |
Influence of beta-adrenoceptor antagonists on hemorrhage-induced cellular immune suppression.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Apoptosis; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Immunity, Cellular; Interleukin-10; Killer Cells, Natural; Lymphocytes; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Shock, Hemorrhagic; Spleen; Tumor Necrosis Factor-alpha | 2002 |
Determination of beta-adrenergic receptor blocking pharmaceuticals in United States wastewater effluent.
Topics: Adrenergic beta-Antagonists; Metoprolol; Mississippi; Nadolol; New York; Propranolol; Texas; Waste Disposal, Fluid; Water Pollutants, Chemical | 2003 |
Carvedilol increases the production of interleukin-12 and interferon-gamma and improves the survival of mice infected with the encephalomyocarditis virus.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiovirus Infections; Carvedilol; Dose-Response Relationship, Drug; Encephalomyocarditis virus; Interferon-gamma; Interleukin-12; Male; Metoprolol; Mice; Mice, Inbred DBA; Myocarditis; Propanolamines; Propranolol; Survival Rate | 2003 |
[Study on sampling preconcentration method combining electrostacking with isotachophoresis in capillary electrophoresis].
Topics: Electrolytes; Electrophoresis; Electrophoresis, Capillary; Metoprolol; Propranolol; Specimen Handling | 2001 |
[Role of beta-adrenoceptor antagonists in the control of kindling models in rats].
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Female; Kindling, Neurologic; Male; Metoprolol; Mice; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1 | 2000 |
Regulation of norepinephrine-induced proliferation in cardiac fibroblasts by interleukin-6 and p42/p44 mitogen activated protein kinase.
Topics: Adrenergic beta-Antagonists; Animals; Blotting, Western; Cell Division; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flavonoids; Interleukin-6; Metoprolol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Norepinephrine; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Ribonucleases; RNA, Messenger; Signal Transduction; Time Factors | 2003 |
Interaction between noradrenaline or adrenaline and the beta 1-adrenergic receptor in the nervous system triggers early metamorphosis of larvae in the ascidian, Ciona savignyi.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Epinephrine; Immunohistochemistry; Isoproterenol; Larva; Metamorphosis, Biological; Metoprolol; Nervous System; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic, beta; Urochordata | 2003 |
Direct enantiomeric resolution of (+/-)-atenolol, (+/-)-metoprolol, and (+/-)-propranolol by impregnated TLC using L-aspartic acid as chiral selector.
Topics: Adrenergic beta-Antagonists; Aspartic Acid; Atenolol; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Metoprolol; Propranolol; Solvents; Stereoisomerism | 2003 |
Comparison of frequency of recurrent syncope after beta-blocker therapy versus conservative management for patients with vasovagal syncope.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Comorbidity; Female; Humans; Male; Metoprolol; Middle Aged; Pindolol; Proportional Hazards Models; Propranolol; Recurrence; Syncope, Vasovagal; Treatment Failure | 2003 |
Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Heart Atria; Heart Failure; Heart Rate; Humans; In Vitro Techniques; Male; Metoprolol; Mice; Mice, Transgenic; Middle Aged; Myocardial Contraction; Organ Specificity; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Species Specificity; Xamoterol | 2003 |
Polymeric matrix membrane sensors for sensitive potentiometric determination of some beta-blockers in pharmaceutical preparations.
Topics: Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Indicators and Reagents; Ions; Metoprolol; Phosphates; Polyvinyl Chloride; Potentiometry; Propranolol; Sensitivity and Specificity; Timolol; Tungsten Compounds | 2003 |
Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Animals; Biological Transport; Chromatography, High Pressure Liquid; Drug Carriers; Injections, Intravenous; Iontophoresis; Irritants; Liposomes; Metoprolol; Oxprenolol; Propranolol; Rats; Skin; Skin Absorption; Sotalol; Stereoisomerism; Timolol | 2003 |
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aortic Coarctation; Atenolol; Blood Pressure; Clenbuterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Hypotension; Isoproterenol; Male; Metoprolol; Microinjections; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2004 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antioxidants; Autoimmune Diseases; Blood Pressure; Body Weight; Carbazoles; Cardiotonic Agents; Carvedilol; Heart Rate; Metoprolol; Myocarditis; Myocardium; Nuclease Protection Assays; Organ Size; Propanolamines; Propranolol; Rats; Ribonucleases; Thiobarbituric Acid Reactive Substances | 2004 |
Cardioprotective effects of carvedilol on acute autoimmune myocarditis.
Topics: Administration, Oral; Animals; Autoimmune Diseases; Carbazoles; Cardiotonic Agents; Carvedilol; Dose-Response Relationship, Drug; Metoprolol; Myocarditis; Myocardium; Myosins; Propanolamines; Propranolol; Proteins; Rats; Rats, Inbred Lew; Thiobarbituric Acid Reactive Substances | 2004 |
Intestinal absorption and hepatic extraction of propranolol and metoprolol in rats with bilateral ureteral ligation.
Topics: Adrenergic beta-Antagonists; Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Glucokinase; Glucosephosphate Dehydrogenase; Intestinal Absorption; Ligation; Liver; Male; Metoprolol; Propranolol; Rats; Rats, Wistar; Renal Insufficiency; Ureter | 2004 |
Enantioseparation using sulfated cyclosophoraoses as a novel chiral additive in capillary electrophoresis.
Topics: Atenolol; Electrolytes; Electrophoresis, Capillary; Isoproterenol; Metoprolol; Molecular Structure; Norepinephrine; Oligosaccharides; Propranolol; Rhizobium leguminosarum; Stereoisomerism | 2004 |
Pharmacokinetics and metabolism of metoprolol and propranolol in the female DA and female Wistar rat: the female DA rat is not always an animal model for poor metabolizers of CYP2D6.
Topics: Animals; Area Under Curve; Cytochrome P-450 CYP2D6; Female; Male; Metoprolol; Models, Animal; Propranolol; Rats; Rats, Inbred Strains; Rats, Wistar | 2005 |
Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Gene Expression; Humans; Inhibitory Concentration 50; Metoprolol; Oocytes; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Propanolamines; Propranolol; Species Specificity; Xenopus | 2005 |
Initial risk assessment for three beta-blockers found in the aquatic environment.
Topics: Adrenergic beta-Antagonists; Animals; Araceae; Atenolol; Biomarkers; Chlorophyta; Daphnia; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Metoprolol; Propranolol; Risk Assessment; Toxicity Tests, Acute; Water Pollutants, Chemical | 2005 |
Suppression by propranolol and amiodarone of an electrical storm refractory to metoprolol and amiodarone.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Dose-Response Relationship, Drug; Drug Therapy, Combination; Equipment Failure; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propranolol; Recurrence; Tachycardia, Ventricular; Treatment Failure | 2005 |
On-line cation-exchange preconcentration and capillary electrophoresis coupled by tee joint interface.
Topics: Ammonium Chloride; Buffers; Cations; Chromatography, Ion Exchange; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Metoprolol; Propranolol; Sensitivity and Specificity; Sodium Chloride | 2005 |
[Correlation between absorption rates of beta-adrenoreceptor antagonists in rat small intestine and their molecular structures].
Topics: Adrenergic beta-Antagonists; Animals; Intestinal Absorption; Intestine, Small; Metoprolol; Molecular Structure; Nadolol; Propranolol; Rats; Regression Analysis | 2005 |
[Study of large-volume electrokinetic injection of capillary zone electrophoresis by using transient isotachophoresis].
Topics: Acetonitriles; Antihypertensive Agents; Buffers; Cations; Electrophoresis; Electrophoresis, Capillary; Flow Injection Analysis; Hydrogen-Ion Concentration; Metoprolol; Propranolol; Sodium Chloride; Temperature; Time Factors | 2005 |
Central beta-adrenoceptors mediate phasic and sustained components of hemodynamic responses to acute behavioral stress.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Cardiac Output; Central Nervous System; Cold Temperature; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reflex, Startle; Stress, Physiological; Time Factors; Vascular Resistance; Wakefulness | 2005 |
Effects of beta-adrenoceptor antagonists in the neural nitric oxide release induced by electrical field stimulation and sodium channel activators in the rabbit corpus cavernosum.
Topics: Aconitine; Adrenergic beta-Antagonists; Animals; Atenolol; Betaxolol; Binding Sites; Electric Stimulation; In Vitro Techniques; Insect Proteins; Male; Metoprolol; Muscle Relaxation; Neurotoxins; Nitric Oxide; Penis; Propanolamines; Propranolol; Rabbits; Saxitoxin; Scorpion Venoms; Sodium Channel Agonists; Tetrodotoxin; Veratridine | 2005 |
Beta1- or beta2-blockers to improve hemodynamics following endotracheal adrenaline administration.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dogs; Epinephrine; Female; Heart Rate; Injections; Male; Metoprolol; Propranolol; Trachea | 2005 |
Gas chromatographic-mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol.
Topics: Adrenergic beta-Antagonists; Atenolol; Gas Chromatography-Mass Spectrometry; Humans; Metoprolol; Propranolol; Reference Standards; Sensitivity and Specificity | 2005 |
Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates.
Topics: Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Genetic Techniques; Hepatocytes; Humans; Metoprolol; Microsomes, Liver; Polymorphism, Genetic; Propafenone; Propranolol; Quinidine | 2005 |
Carvedilol blocks beta2- more than beta1-adrenoceptors in human heart.
Topics: Adrenergic beta-Antagonists; Calcium Channels, L-Type; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Epinephrine; Heart Atria; Heart Failure; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Metoprolol; Myocardial Contraction; Myocardium; Norepinephrine; Patch-Clamp Techniques; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2006 |
Post-mortem redistribution of three beta-blockers in the rabbit.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Infusions, Intravenous; Male; Metoprolol; Models, Animal; Postmortem Changes; Propranolol; Rabbits; Tissue Distribution | 2006 |
Application of substrate depletion assay for early prediction of nonlinear pharmacokinetics in drug discovery: assessment of nonlinearity of metoprolol, timolol, and propranolol.
Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; Blood Proteins; Drug Design; Female; Male; Metabolic Clearance Rate; Metoprolol; Microsomes, Liver; Nonlinear Dynamics; Predictive Value of Tests; Propranolol; Rats; Rats, Wistar; Substrate Specificity; Timolol | 2005 |
Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.
Topics: Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Dexamethasone; Etoposide; Furosemide; Humans; Metoprolol; Nadolol; Pharmaceutical Preparations; Propranolol; Quinidine; Rhodamine 123; Spectrometry, Mass, Electrospray Ionization; Sulfasalazine; Verapamil | 2006 |
Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy.
Topics: Adrenergic beta-Antagonists; Binding Sites; Carbazoles; Cardiovascular Diseases; Carvedilol; Cell Line; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Membrane Potentials; Metoprolol; Mutation; Potassium Channel Blockers; Propanolamines; Propranolol; Protein Binding; Transfection | 2006 |
Quantitation of atenolol, metoprolol, and propranolol in postmortem human fluid and tissue specimens via LC/APCI-MS.
Topics: Adrenergic beta-Antagonists; Aerospace Medicine; Atenolol; Atmospheric Pressure; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; Metoprolol; Molecular Structure; Postmortem Changes; Propranolol; Spectrometry, Mass, Electrospray Ionization | 2006 |
Stereoisomer quantification of the beta-blocker drugs atenolol, metoprolol, and propranolol in wastewaters by chiral high-performance liquid chromatography-tandem mass spectrometry.
Topics: Adrenergic beta-Antagonists; Atenolol; Canada; Chromatography, High Pressure Liquid; Mass Spectrometry; Metoprolol; Molecular Structure; Propranolol; Reproducibility of Results; Sewage; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2006 |
Differing effects of metoprolol and propranolol on large vessel and microvessel responsiveness in a porcine model of coronary spasm.
Topics: Acetylcholine; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cholinergic Agents; Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Dehydroascorbic Acid; Disease Models, Animal; Laser-Doppler Flowmetry; Metoprolol; Nitric Oxide; Propranolol; Serotonin; Serotonin Agents; Swine | 2006 |
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil | 2007 |
Comparative ecotoxicological hazard assessment of beta-blockers and their human metabolites using a mode-of-action-based test battery and a QSAR approach.
Topics: Adrenergic beta-Antagonists; Atenolol; Chlorophyta; Endpoint Determination; Humans; Liposomes; Metoprolol; Photosynthesis; Propranolol; Quantitative Structure-Activity Relationship; Risk Assessment; Toxicity Tests; Water Pollutants, Chemical | 2006 |
Elimination of beta-blockers in sewage treatment plants.
Topics: Adrenergic beta-Antagonists; Adsorption; Atenolol; Chromatography, High Pressure Liquid; Kinetics; Metoprolol; Molecular Structure; Propranolol; Sotalol; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2007 |
Kinetics and degradation products for direct photolysis of beta-blockers in water.
Topics: Adrenergic beta-Antagonists; Atenolol; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Free Radical Scavengers; Fresh Water; Industrial Waste; Kinetics; Magnetic Resonance Spectroscopy; Metoprolol; Oxidation-Reduction; Photolysis; Propranolol; Seasons; Water Pollutants, Chemical | 2007 |
Left ventricular volume and function in cynomolgus monkeys using real-time three-dimensional echocardiography.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Echocardiography, Three-Dimensional; Heart Ventricles; Macaca fascicularis; Male; Metoprolol; Propranolol; Ventricular Function; Verapamil | 2007 |
Semipermanent capillary coatings in mixed organic-water solvents for CE.
Topics: Anions; Drug Stability; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Lipid Bilayers; Methanol; Metoprolol; Propranolol; Quaternary Ammonium Compounds; Solvents | 2007 |
Effect of beta-adrenoceptors on the behaviour induced by the neuropeptide glutamic acid isoleucine amide.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Dobutamine; Grooming; Isoproterenol; Male; Metoprolol; Motor Activity; Oligopeptides; Phentolamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1 | 2007 |
Divergence of hypertrophic growth and fetal gene profile: the influence of beta-blockers.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Gene Expression Profiling; Gene Expression Regulation; Metoprolol; Propanolamines; Propranolol | 2007 |
Adsorption of beta blockers to environmental surfaces.
Topics: Adrenergic beta-Antagonists; Adsorption; Benzenesulfonates; Confidence Intervals; Environment; Hydrogen-Ion Concentration; Metoprolol; Minerals; Nadolol; Propranolol; Rivers; Surface Properties; Surface-Active Agents | 2007 |
Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Chromatography, Liquid; Humans; Labetalol; Linear Models; Metoprolol; Pindolol; Propranolol; Sensitivity and Specificity; Tandem Mass Spectrometry | 2008 |
Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Buffers; Celiprolol; Clenbuterol; Electroosmosis; Electrophoresis, Capillary; Fenoterol; Hydrogen-Ion Concentration; Isoproterenol; Metal Nanoparticles; Metoprolol; Propranolol; Reproducibility of Results; Terbutaline; Titanium; Uncertainty | 2008 |
Enantiomeric separation by using nano-liquid chromatography with on-column focusing.
Topics: Adrenergic beta-Antagonists; Alprenolol; Calibration; Chromatography, Liquid; Metoprolol; Nanotechnology; Oxprenolol; Particle Size; Propranolol; Reproducibility of Results; Silicon Dioxide; Stereoisomerism; Time Factors; Vancomycin | 2008 |
Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat.
Topics: Administration, Oral; Algorithms; Animals; Cimetidine; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Male; Metoprolol; Models, Animal; Perfusion; Permeability; Propranolol; Rats; Rats, Wistar | 2009 |
HO-1-u-1 model for screening sublingual drug delivery--influence of pH, osmolarity and permeation enhancer.
Topics: Adjuvants, Pharmaceutic; Administration, Sublingual; Adrenergic beta-Antagonists; Animals; Atenolol; Biological Transport; Cell Line, Tumor; Chromatography, High Pressure Liquid; Diffusion; Drug Evaluation, Preclinical; Glycodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Metoprolol; Models, Biological; Mouth Mucosa; Osmolar Concentration; Permeability; Propranolol; Sus scrofa | 2009 |
Spatial metabolic fingerprinting using FT-IR spectroscopy: investigating abiotic stresses on Micrasterias hardyi.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Eukaryota; Mefenamic Acid; Metoprolol; Propranolol; Spectroscopy, Fourier Transform Infrared; Toxicity Tests, Acute; Water Pollutants, Chemical | 2008 |
The effects of beta-adrenoceptor antagonists on proinflammatory cytokine concentrations after subarachnoid hemorrhage in rats.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Disease Models, Animal; Inflammation Mediators; Interleukin-6; Male; Metoprolol; Neuroprotective Agents; Propranolol; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Inhibition of pancreatic cancer cell proliferation by propranolol occurs through apoptosis induction: the study of beta-adrenoceptor antagonist's anticancer effect in pancreatic cancer cell.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Annexin A5; Antineoplastic Agents; Apoptosis; Butoxamine; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Metoprolol; Pancreatic Neoplasms; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger | 2009 |
Influence of plasma protein binding on pharmacodynamics: Estimation of in vivo receptor affinities of beta blockers using a new mechanism-based PK-PD modelling approach.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Blood Proteins; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Metoprolol; Models, Biological; Propranolol; Protein Binding; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Timolol | 2009 |
Heart-cut capillary electrophoresis for drug analysis in mouse blood with electrochemical detection.
Topics: Animals; Chromatography, Micellar Electrokinetic Capillary; Electrochemistry; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Metoprolol; Mice; Pharmaceutical Preparations; Propranolol | 2009 |
Molecular determinants of local anesthetic action of beta-blocking drugs: Implications for therapeutic management of long QT syndrome variant 3.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Carbazoles; Carvedilol; Cell Line; Electrophysiology; Heart; Humans; Long QT Syndrome; Metoprolol; Propanolamines; Propranolol; Sodium Channels | 2010 |
Photo-induced environmental depletion processes of beta-blockers in river waters.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Photochemical Processes; Propranolol; Rivers; Sterilization; Sunlight | 2009 |
Analysis of beta-agonists and beta-blockers in urine using hollow fibre-protected liquid-phase microextraction with in situ derivatization followed by gas chromatography/mass spectrometry.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Chemical Fractionation; Clenbuterol; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Linear Models; Metoprolol; Propranolol; Reproducibility of Results; Sensitivity and Specificity; Sodium Chloride; Solvents; Temperature | 2009 |
Heart rate variability in rats with experimental chronic heart failure and long-term exposure to beta-adrenoblockers.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Benzopyrans; Bisoprolol; Ethanolamines; Heart Failure; Heart Rate; Male; Metoprolol; Nebivolol; Pindolol; Propranolol; Rats | 2009 |
Interaction of beta-blockers with the renal uptake transporter OCT2.
Topics: Adrenergic beta-Antagonists; Biological Transport; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Humans; Kidney; Metformin; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propanolamines; Propranolol | 2009 |
Autonomic control of heart rate by metabolically sensitive skeletal muscle afferents in humans.
Topics: Adrenergic beta-Antagonists; Adult; Baroreflex; Blood Pressure; Exercise; Glycopyrrolate; Heart Rate; Humans; Ischemia; Isometric Contraction; Male; Metoprolol; Muscle, Skeletal; Neurons, Afferent; Parasympathetic Nervous System; Propranolol; Sympathetic Nervous System; Young Adult | 2010 |
Determination of permeation resistance distribution in in vitro cell monolayer permeation experiments.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Caco-2 Cells; Cell Culture Techniques; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Ibuprofen; Metoprolol; Models, Biological; Propranolol | 2010 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment | 2011 |
Electrochemical degradation of beta-blockers. Studies on single and multicomponent synthetic aqueous solutions.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, High Pressure Liquid; Electrochemistry; Metoprolol; Propranolol | 2010 |
Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment?
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cause of Death; Chi-Square Distribution; Databases, Factual; Electrocardiography; Female; Genetic Counseling; Genetic Predisposition to Disease; Genetic Testing; Heterozygote; Humans; Male; Metoprolol; Middle Aged; Pedigree; Primary Prevention; Probability; Prognosis; Propranolol; Registries; Retrospective Studies; Risk Assessment; Survival Analysis; Syndrome | 2010 |
The biowaiver extension for BCS class III drugs: the effect of dissolution rate on the bioequivalence of BCS class III immediate-release drugs predicted by computer simulation.
Topics: Amoxicillin; Atenolol; Cell Membrane Permeability; Cimetidine; Computer Simulation; Gastric Emptying; Gastrointestinal Tract; Humans; Metoprolol; Pharmaceutical Preparations; Propranolol; Software | 2010 |
Indirect role of beta2-adrenergic receptors in the mechanism of analgesic action of nonsteroidal antiinflammatory drugs.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Male; Metoprolol; Pain; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2 | 2010 |
The interactivities with lipid membranes differentially characterize selective and nonselective beta1-blockers.
Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia; Anesthetics; Atenolol; Biomimetics; Lipid Bilayers; Lipids; Liposomes; Membranes, Artificial; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 2010 |
Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model.
Topics: Animals; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Extracellular Space; Furosemide; Liver; Liver Cirrhosis; Liver Transplantation; Male; Metoprolol; Models, Biological; Omeprazole; Organ Size; Oxygen Consumption; Pharmaceutical Preparations; Pharmacokinetics; Propranolol; Rats; Rats, Wistar; Spironolactone; Transplantation Conditioning; Water | 2010 |
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Connexin 43; Gap Junctions; Isosorbide Dinitrate; Male; Metoprolol; Myocardial Ischemia; Myocardium; Nitric Oxide Donors; Propranolol; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Restraint, Physical; Stress, Physiological | 2010 |
Does remodeling of gap junctions and connexin expression contribute to arrhythmogenesis? Study in an immobilization rat model.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Arrhythmias, Cardiac; Connexin 43; Gap Junctions; Isosorbide Dinitrate; Male; Metoprolol; Myocardial Ischemia; Myocardium; Nitric Oxide Donors; Propranolol; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Restraint, Physical; Stress, Physiological | 2010 |
The activation of β2-adrenergic receptors in naïve rats causes a reduction of blood glutamate levels: relevance to stress and neuroprotection.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Glutamic Acid; Male; Metoprolol; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Stress, Physiological | 2011 |
Heart failure: acute ischemic events in HF--should we include sudden death?
Topics: Adrenergic beta-1 Receptor Antagonists; Antihypertensive Agents; Benzopyrans; Death, Sudden, Cardiac; Disease Progression; Ethanolamines; Heart Failure; Humans; Metoprolol; Myocardial Ischemia; Nebivolol; Prognosis; Propranolol; Vasodilator Agents | 2011 |
Degradation of pharmaceutical beta-blockers by electrochemical advanced oxidation processes using a flow plant with a solar compound parabolic collector.
Topics: Adrenergic beta-Antagonists; Atenolol; Boron; Carbon; Diamond; Electrochemistry; Ferric Compounds; Hydrogen Peroxide; Iron; Kinetics; Metoprolol; Nitrates; Nitrogen Compounds; Oxidation-Reduction; Photochemistry; Platinum; Propranolol; Quaternary Ammonium Compounds; Sunlight; Water Pollutants, Chemical; Water Purification | 2011 |
[Ischemic heart disease in elderly patients of behavioral type A (psychosocial and clinic functional changes, possibilities for correction)].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Anti-Anxiety Agents; Behavioral Symptoms; Benzodiazepines; Drug Therapy, Combination; Female; Humans; Lipids; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propranolol; Psychiatric Status Rating Scales; Psychology; Stress, Psychological; Treatment Outcome | 2011 |
Nadolol block of Nav1.5 does not explain its efficacy in the long QT syndrome.
Topics: Adrenergic beta-Antagonists; Cell Line; Humans; Long QT Syndrome; Metoprolol; Mutation; Nadolol; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Propranolol; Sodium Channel Blockers; Sodium Channels | 2012 |
Standardization of an ex vivo method for determination of intestinal permeability of drugs using everted rat intestine apparatus.
Topics: Animals; Atenolol; Intestinal Absorption; Intestinal Mucosa; Male; Metoprolol; Models, Biological; Permeability; Phenolsulfonphthalein; Propranolol; Rats; Rats, Wistar | 2012 |
Pharmacophore modeling for hERG channel facilitation.
Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis | 2012 |
Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
Topics: Adrenergic Antagonists; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Failure; Labetalol; Linear Models; Liver; Liver Cirrhosis; Liver Diseases; Male; Metabolic Clearance Rate; Metoprolol; Microsomes, Liver; Models, Biological; Necrosis; Nonlinear Dynamics; Perfusion; Propranolol; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Fate of β-blockers in aquifer material under nitrate reducing conditions: batch experiments.
Topics: Adrenergic beta-Antagonists; Atenolol; Environmental Monitoring; Groundwater; Kinetics; Metoprolol; Models, Chemical; Nitrates; Oxidation-Reduction; Propranolol; Water Pollutants, Chemical | 2012 |
[Chiral separation of five beta-blockers using di-n-hexyl L-tartrate-boric acid complex as mobile phase additive by reversed-phase liquid chromatography].
Topics: Adrenergic beta-Antagonists; Boric Acids; Chromatography, Reverse-Phase; Dicarboxylic Acids; Metoprolol; Propanolamines; Propranolol; Stereoisomerism; Sugar Acids | 2012 |
Simultaneous enantiomeric determination of propranolol, metoprolol, pindolol, and atenolol in natural waters by HPLC on new polysaccharide-based stationary phase using a highly selective molecularly imprinted polymer extraction.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, High Pressure Liquid; Environmental Monitoring; Metoprolol; Molecular Imprinting; Molecular Structure; Pindolol; Polysaccharides; Propranolol; Rivers; Solid Phase Extraction; Stereoisomerism; Water | 2012 |
A prospective, 1-year follow-up study of postural tachycardia syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adult; Anti-Inflammatory Agents; Atenolol; Cholinesterase Inhibitors; Female; Fludrocortisone; Follow-Up Studies; Heart Rate; Humans; Male; Metoprolol; Midodrine; Nadolol; Norepinephrine; Postural Orthostatic Tachycardia Syndrome; Propranolol; Prospective Studies; Pyridostigmine Bromide; Severity of Illness Index; Sodium; Tilt-Table Test; Virus Diseases | 2012 |
Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carbazoles; Carvedilol; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cholesterol, Dietary; Free Radicals; Heart Rate; Lipids; Macrophages; Male; Metoprolol; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Plaque, Atherosclerotic; Propanolamines; Propranolol; Superoxides | 2012 |
Novel insights into beta-blocker therapy for long QT syndromes.
Topics: Adrenergic beta-Antagonists; Female; Humans; Long QT Syndrome; Male; Metoprolol; Nadolol; Propranolol | 2012 |
Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Child; Disease-Free Survival; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Metoprolol; Nadolol; Prognosis; Propranolol; Secondary Prevention; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Potentiometric propranolol-selective sensor based on molecularly imprinted polymer.
Topics: Adrenergic Antagonists; Atenolol; Calibration; Electrodes; Metoprolol; Microscopy, Electron, Scanning; Models, Chemical; Molecular Imprinting; Nanoparticles; Nanotechnology; Pharmaceutical Preparations; Polymers; Potentiometry; Propranolol; Solvents; Water | 2013 |
Oxidation-coagulation of β-blockers by K2FeVIO4 in hospital wastewater: assessment of degradation products and biodegradability.
Topics: Adrenergic beta-Antagonists; Atenolol; Biodegradation, Environmental; Chromatography, Liquid; Data Interpretation, Statistical; Hospitals; Iron; Mass Spectrometry; Medical Waste; Medical Waste Disposal; Metoprolol; Models, Theoretical; Oxidation-Reduction; Propranolol; Water Pollutants, Chemical | 2013 |
Multi-residue enantiomeric analysis of pharmaceuticals and their active metabolites in the Guadalquivir River basin (South Spain) by chiral liquid chromatography coupled with tandem mass spectrometry.
Topics: Atenolol; Chromatography, Liquid; Environmental Monitoring; Fluoxetine; Metoprolol; Pharmaceutical Preparations; Propanolamines; Propranolol; Reproducibility of Results; Rivers; Sensitivity and Specificity; Spain; Stereoisomerism; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2013 |
Toxicity and enantiospecific differences of two β-blockers, propranolol and metoprolol, in the embryos and larvae of zebrafish (Danio rerio).
Topics: Adrenergic beta-Antagonists; Animals; Embryo, Nonmammalian; Larva; Metoprolol; Propranolol; Stereoisomerism; Transcription, Genetic; Zebrafish | 2014 |
Penicillin G as a novel chiral selector in capillary electrophoresis.
Topics: Anti-Bacterial Agents; Benzofurans; Citalopram; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Methanol; Metoprolol; Penicillin G; Propranolol; Pyrrolidines; Sertraline; Solubility; Stereoisomerism; Temperature | 2014 |
Triptan use after starting prophylactic migraine treatment: a retrospective cohort study in a primary care population.
Topics: Adult; Analgesics; Cohort Studies; Female; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Primary Health Care; Propranolol; Retrospective Studies; Tryptamines | 2014 |
Effects of lifestyle changes and high-dose β-blocker therapy on exercise capacity in children, adolescents, and young adults with hypertrophic cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aging; Blood Pressure; Cardiomyopathy, Hypertrophic, Familial; Child; Dose-Response Relationship, Drug; Exercise; Exercise Test; Female; Follow-Up Studies; Heart Rate; Humans; Life Style; Male; Metoprolol; Propranolol; Random Allocation; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Young Adult | 2015 |
Effects of one month treatment with propranolol and metoprolol on the relaxant and contractile function of isolated trachea from rats exposed to cigarette smoke for four months.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Lung; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Tobacco Smoke Pollution; Trachea | 2014 |
Effects of long-term application of metoprolol and propranolol in a rat model of smoking.
Topics: Adrenergic beta-Antagonists; Animals; Bronchoalveolar Lavage Fluid; Interleukin-8; Lung; Lung Injury; Male; Metoprolol; Models, Animal; Mucus; Propranolol; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Smoking; Tobacco Smoke Pollution; Tumor Necrosis Factor-alpha | 2014 |
Functional and histological assessment of an experimental model of Takotsubo's cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Fibrosis; Heart; Hemodynamics; Male; Metoprolol; Microscopy, Electron; Myocardium; Necrosis; Propranolol; Rats; Rats, Sprague-Dawley; Takotsubo Cardiomyopathy | 2014 |
Beta-blockers in the environment: part II. Ecotoxicity study.
Topics: Adrenergic beta-Antagonists; Aliivibrio fischeri; Animals; Aquatic Organisms; Araceae; Chlorophyta; Daphnia; Ecotoxicology; Environment; Environmental Monitoring; Humans; Metoprolol; Models, Chemical; Propranolol; Scenedesmus; Water Pollutants, Chemical | 2014 |
Human and simulated intestinal fluids as solvent systems to explore food effects on intestinal solubility and permeability.
Topics: Animals; Atenolol; Body Fluids; Carbazoles; Carvedilol; Humans; Intestinal Secretions; Male; Metoprolol; Permeability; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Solubility; Solvents | 2014 |
Inhibition of human melanoma growth by a non-cardioselective β-blocker.
Topics: Adrenergic beta-Antagonists; Adult; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Melanoma; Metoprolol; Middle Aged; Neovascularization, Pathologic; Propranolol; Transcriptome; Xenograft Model Antitumor Assays | 2015 |
Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution.
Topics: Chemistry, Pharmaceutical; Duodenum; Equipment Design; Fasting; Gastric Absorption; Gastric Emptying; Gastrointestinal Transit; Hydrogen-Ion Concentration; Intestinal Absorption; Jejunum; Kinetics; Materials Testing; Metoprolol; Models, Biological; Models, Chemical; Propranolol; Solubility; Stomach; Tablets; Technology, Pharmaceutical | 2014 |
Efficacy of different beta-blockers in the treatment of long QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Death, Sudden, Cardiac; Female; Genotype; Heart Arrest; Humans; Infant; Infant, Newborn; Long QT Syndrome; Male; Metoprolol; Multivariate Analysis; Nadolol; Proportional Hazards Models; Propranolol; Registries; Regression Analysis; Risk Factors; Syncope; Time Factors; Treatment Outcome; Young Adult | 2014 |
Impact of alpha- and beta-adrenergic receptor blockers on fractional flow reserve and index of microvascular resistance.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Cardiac Catheterization; Female; Fractional Flow Reserve, Myocardial; Humans; Male; Metoprolol; Phentolamine; Propranolol; Vascular Resistance | 2014 |
[Effect of acute exposure to high altitude on pharmacokinetics of propranolol and metoprolol in rats].
Topics: Altitude; Animals; Chromatography, Liquid; Metoprolol; Propranolol; Protein Binding; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2014 |
How to easily provide zero order release of freely soluble drugs from coated pellets.
Topics: Carbohydrates; Cellulose; Dosage Forms; Drug Delivery Systems; Drug Liberation; Metoprolol; Polyvinyls; Propranolol | 2015 |
Direct ionization of solid-phase microextraction fibers for quantitative drug bioanalysis: from peripheral circulation to mass spectrometry detection.
Topics: Animals; Chromatography, Liquid; Metoprolol; Propranolol; Rats; Solid Phase Microextraction; Tandem Mass Spectrometry | 2015 |
Simultaneous determination of blockers and agonists by on-fiber derivatization in self-made solid-phase microextraction coating fiber.
Topics: Acrylic Resins; Adsorption; Clenbuterol; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Metoprolol; Phase Transition; Polyethylene Glycols; Propranolol; Reproducibility of Results; Saliva; Siloxanes; Solid Phase Microextraction | 2015 |
The development of the LC-MS/MS method based on S-9 biotransformation for detection of metabolites of selected β-adrenolytics in surface water.
Topics: Adrenergic beta-Antagonists; Animals; Biotransformation; Bisoprolol; Chromatography, Liquid; Liver; Male; Metoprolol; Poland; Propranolol; Rats, Sprague-Dawley; Rivers; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
β-Adrenergic receptor agonist increases voltage-gated Na(+) currents in medial prefrontal cortex pyramidal neurons.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Metoprolol; Prefrontal Cortex; Propranolol; Protein Kinase C; Pyramidal Cells; Rats; Receptors, Adrenergic, beta-1; Voltage-Gated Sodium Channels | 2015 |
Transcriptional Responses in Adult Zebrafish (Danio rerio) Exposed to Propranolol and Metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Female; Fish Proteins; Gene Expression Regulation; Male; Metoprolol; Organ Specificity; Oxidative Stress; Propranolol; RNA, Messenger; Water Pollutants, Chemical; Zebrafish | 2015 |
Rapid chiral separation of atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid using supercritical fluid chromatography-tandem mass spectrometry - Application to wetland microcosms.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, Supercritical Fluid; Metoprolol; Propranolol; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry; Water Pollutants, Chemical; Wetlands | 2015 |
Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases; Glucose Transporter Type 4; HEK293 Cells; Humans; Insulin Resistance; Isoproterenol; Metoprolol; Mice; Myocardium; Myocytes, Cardiac; Propranolol; Rats; Receptors, Adrenergic, beta; Signal Transduction | 2016 |
Double-wavelength overlapping resonance Rayleigh scattering technique for the simultaneous quantitative analysis of three β-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Atenolol; Erythrosine; Fluorescent Dyes; Humans; Light; Limit of Detection; Metoprolol; Propranolol; Scattering, Radiation; Spectrometry, Fluorescence; Spectrophotometry | 2016 |
Liquid chromatographic enantioseparation of three beta-adrenolytics using new derivatizing reagents synthesized from (S)-ketoprofen and confirmation of configuration of diastereomers.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Ketoprofen; Limit of Detection; Metoprolol; Models, Molecular; Molecular Conformation; Propranolol; Stereoisomerism | 2016 |
Application of rifampicin as a chiral selector for enantioresolution of basic drugs using capillary electrophoresis.
Topics: Anti-Bacterial Agents; Electrophoresis, Capillary; Metoprolol; Propranolol; Rifampin; Stereoisomerism | 2016 |
Development of potential candidate reference materials for drugs in bottom sediment, cod and herring tissues.
Topics: Acenocoumarol; Animals; Carbamazepine; Chromatography, Liquid; Environmental Monitoring; Fishes; Metoprolol; Naproxen; Propranolol; Reference Standards; Reproducibility of Results; Seafood; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2017 |
Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance.
Topics: Animals; Atenolol; Biotransformation; Carbamazepine; Diazepam; Diclofenac; Drug Evaluation, Preclinical; Female; Kinetics; Liver; Metoprolol; Models, Animal; Oncorhynchus mykiss; Phenylbutazone; Propranolol; Tandem Mass Spectrometry; Water Pollutants, Chemical; Xenobiotics | 2017 |
Curing mechanism of flexible aqueous polymeric coatings.
Topics: Drug Compounding; Drug Implants; Drug Liberation; Excipients; Humidity; Lactose; Methylcellulose; Metoprolol; Plasticizers; Polymers; Polyvinyls; Propranolol; Temperature; Theophylline; Tramadol; Water | 2017 |
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; California; Cohort Studies; Confounding Factors, Epidemiologic; Diabetes Mellitus; Eclampsia; Female; Gestational Age; Heart Defects, Congenital; Heart Failure; Humans; Hyperlipidemias; Hypertension; Labetalol; Logistic Models; Metoprolol; Multivariate Analysis; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Propranolol; Retrospective Studies; Risk; Risk Factors | 2017 |
Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Atenolol; Intestinal Absorption; Intestines; Male; Metoprolol; Propranolol; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2017 |
Metoprolol, propranolol, carvedilol, or labetalol for patients with Takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Reply to: metoprolol, or propranolol, or carvedilol, or labetalol, for patients with takotsubo syndrome?
Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy | 2018 |
Propranolol Versus Metoprolol for Treatment of Electrical Storm in Patients With Implantable Cardioverter-Defibrillator.
Topics: Adrenergic beta-Antagonists; Aged; Defibrillators, Implantable; Female; Humans; Length of Stay; Male; Metoprolol; Middle Aged; Propranolol; Prospective Studies; Tachycardia; Ventricular Fibrillation | 2018 |
Why Is Propranolol Better Than Metoprolol in Acute Treatment of Electrical Storm?
Topics: Defibrillators, Implantable; Humans; Metoprolol; Physical Exertion; Propranolol | 2018 |
β-blockers interfere with cell homing receptors and regulatory proteins in a model of spontaneously hypertensive rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; beta-Arrestin 1; beta-Arrestin 2; Carbazoles; Carvedilol; Cell Movement; Chemokine CXCL12; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Hypertension; Kidney; Liver; Lung; Metoprolol; Myocardium; NF-kappa B; Propanolamines; Propranolol; Rats, Inbred SHR; Receptors, CXCR; Receptors, CXCR4; Signal Transduction | 2018 |
Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio.
Topics: Adrenergic beta-Antagonists; Animals; Embryo, Nonmammalian; Heart Rate; Hydrogen-Ion Concentration; Metoprolol; Phenotype; Propranolol; Toxicity Tests; Water Pollutants, Chemical; Zebrafish | 2018 |
Beta-blocker subtypes and risk of low birth weight in newborns.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Birth Weight; California; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Infant, Small for Gestational Age; Labetalol; Male; Metoprolol; Pregnancy; Prevalence; Propranolol; Retrospective Studies | 2018 |
Occurrence and enantiomer profiles of β-blockers in wastewater and a receiving water body and adjacent soil in Tianjin, China.
Topics: Adrenergic beta-Antagonists; Atenolol; China; Environmental Monitoring; Metoprolol; Propranolol; Soil; Stereoisomerism; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
Implications of aging in the treatment of complex arrhythmias.
Topics: Aging; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Metoprolol; Propranolol | 2018 |
Enantioseparation of propranolol, amlodipine and metoprolol by electrochromatography using an open tubular capillary modified with β-cyclodextrin and poly(glycidyl methacrylate) nanoparticles.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metoprolol; Nanoparticles; Polymethacrylic Acids; Propranolol; Stereoisomerism | 2019 |
Use of β2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Cholinergic Antagonists; Denmark; Duration of Therapy; Female; Humans; Male; Metoprolol; Middle Aged; Parkinson Disease; Propranolol; Protective Factors; Pulmonary Disease, Chronic Obstructive; Registries; Risk Factors; Smoking | 2019 |
Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metal-Organic Frameworks; Metoprolol; Propanolamines; Propranolol; Sotalol; Stereoisomerism | 2019 |
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS.
Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil | 2019 |
Dispersive solid-phase extraction of racemic drugs using chiral ionic liquid-metal-organic framework composite sorbent.
Topics: Adrenergic beta-Antagonists; Atenolol; Chromatography, High Pressure Liquid; Copper; Ionic Liquids; Metal-Organic Frameworks; Metoprolol; Pharmaceutical Preparations; Propranolol; Solid Phase Extraction; Solvents; Stereoisomerism | 2020 |
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors | 2021 |
The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury.
Topics: Adrenergic beta-Antagonists; Animals; Carvedilol; Cisplatin; Creatinine; Kidney; Metoprolol; Propranolol; Rats; Technetium Tc 99m Dimercaptosuccinic Acid | 2022 |
Traumatic brain injury induced temperature dysregulation: What is the role of β blockers?
Topics: Abbreviated Injury Scale; Adrenergic beta-Antagonists; Atenolol; Body Temperature; Brain Injuries, Traumatic; Female; Humans; Hyperthermia; Male; Metoprolol; Middle Aged; Propensity Score; Propranolol; Retrospective Studies; Treatment Outcome | 2021 |
Vortex assisted liquid-liquid microextraction based on in situ formation of a natural deep eutectic solvent by microwave irradiation for the determination of beta-blockers in water samples.
Topics: Adrenergic beta-Antagonists; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Liquid Phase Microextraction; Metoprolol; Microwaves; Propranolol; Reproducibility of Results; Solvents; Spectroscopy, Fourier Transform Infrared; Thymol; Water | 2021 |
Solid-phase microextraction for assessment of plasma protein binding, a complement to rapid equilibrium dialysis.
Topics: Animals; Blood Proteins; Chromatography, Liquid; Dialysis; Diclofenac; Metoprolol; Propranolol; Protein Binding; Rats; Solid Phase Microextraction; Tandem Mass Spectrometry | 2021 |
Propranolol and metoprolol: Two comparable drugs with very different post-mortem toxicological profiles.
Topics: Adrenergic beta-Antagonists; Adult; Age Distribution; Aged; Aged, 80 and over; Cardiovascular Diseases; Cause of Death; Databases, Factual; Female; Finland; Forensic Toxicology; Humans; Male; Mental Disorders; Metoprolol; Middle Aged; Propranolol; Substance Abuse Detection | 2021 |
Zeolitic imidazolate framework-67-modified open-tubular column with cyclodextrin for enantioseparation in capillary electrochromatography.
Topics: Amlodipine; Atenolol; Capillary Electrochromatography; Cyclodextrins; Histidine; Metoprolol; Propranolol; Stereoisomerism; Zeolites | 2022 |
Evaluating phospholipid- and protein-water partitioning of two groups of chemicals of emerging concern: Diastereo- and enantioselectivity.
Topics: Liposomes; Metoprolol; Molecular Docking Simulation; Phospholipids; Propranolol; Serum Albumin, Bovine; Sotalol; Water | 2022 |
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro.
Topics: Adrenergic beta-Antagonists; Amines; Atenolol; Autophagy; Cell Proliferation; Child; Endothelial Cells; Hemangioma; Humans; Macrolides; Metoprolol; Propranolol; Sirolimus | 2022 |
Mechanism of β-blocker biodegradation by wastewater microorganisms.
Topics: Adrenergic beta-Antagonists; Atenolol; Metoprolol; Molecular Docking Simulation; Propranolol; Sewage; Wastewater | 2023 |