Page last updated: 2024-08-16

propranolol and isradipine

propranolol has been researched along with isradipine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's7 (33.33)18.2507
2000's4 (19.05)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gollasch, M; Hescheler, J; Klinz, FJ; Rosenthal, W; Schultz, G; Spicher, K1
Cantor, A; Cristal, N1
Burger, KJ; Griebenow, R; Kaufmann, W; Krämer, L; Steffen, HM; Wambach, G; Welzel, D1
Gleerup, G; Hedner, T; Hjørting Hansen, E; Winther, K1
Burger, KJ; Distler, GA; Gross, P; Koppenhagen, K; Welzel, D; Wudel, E1
Carr, AA; Gonasun, LM; Nelson, EB; Prisant, LM; Velasquez, MT; Winer, N1
Ickrath, O; Karsch, KR; Mauser, M; Voelker, W1
Jie, K; Thoolen, MJ; Timmermans, PB; van Brummelen, P; van Zwieten, PA1
Hof, RP1
Hamilton, BP1
Brée, F; Carrupt, PA; Giroud, Y; Testa, B; Tillement, JP; Tsai, RS; Urien, S1
Block, LH; Nauck, M; Rödler, S; Roth, M; Tamm, M1

Reviews

1 review(s) available for propranolol and isradipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for propranolol and isradipine

ArticleYear
Isotonic and isometric responses of blood pressure and heart rate in mild to moderate hypertension with isradipine and propranolol.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise; Exercise Test; Heart Rate; Humans; Hypertension; Isradipine; Male; Middle Aged; Myocardial Contraction; Propranolol; Pyridines; Single-Blind Method

1990
Does antihypertensive therapy affect the natural protection against thrombosis?
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Fibrinolysis; Humans; Hypertension; Isradipine; Male; Middle Aged; Propranolol; Tissue Plasminogen Activator

1991
[The hemodynamic effects of isradipine and nifedipine in hypertension].
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:9

    Topics: Adult; Blood Pressure; Cardiac Output; Dihydropyridines; Female; Heart; Heart Function Tests; Humans; Hypertension; Injections, Intravenous; Isradipine; Male; Middle Aged; Myocardial Contraction; Nifedipine; Propranolol; Stroke Volume

1991
Isradipine vs propranolol in hydrochlorothiazide-treated hypertensives. A multicenter evaluation.
    Archives of internal medicine, 1989, Volume: 149, Issue:11

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Multicenter Studies as Topic; Propranolol; Pyridines; Randomized Controlled Trials as Topic

1989
Treatment of essential hypertension with PN 200-110 (isradipine).
    The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3

    Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Oxadiazoles; Prazosin; Propranolol; Random Allocation; Time Factors

1987

Other Studies

15 other study(ies) available for propranolol and isradipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Atropine; Barium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cell Line; Cell Membrane; Enkephalin, Leucine-2-Alanine; Epinephrine; Evoked Potentials; GTP-Binding Proteins; Immune Sera; Isradipine; Membrane Potentials; Molecular Sequence Data; omega-Conotoxins; Oxadiazoles; Peptides; Peptides, Cyclic; Pertussis Toxin; Pheochromocytoma; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Muscarinic; Virulence Factors, Bordetella; Yohimbine

1991
Isradipine: a new calcium antagonist with strong vasodilatory but negligible cardiodepressive effects.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Female; Heart Rate; Hemodynamics; Humans; Isradipine; Male; Middle Aged; Myocardial Contraction; Propranolol; Pyridines; Vasodilation

1990
Myocardial properties of the new dihydropyridine calcium antagonist isradipine compared to nifedipine with or without additional beta blockade in coronary artery disease.
    The American journal of cardiology, 1989, Jan-01, Volume: 63, Issue:1

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Heart Rate; Humans; Isradipine; Middle Aged; Myocardial Contraction; Nifedipine; Propranolol; Pyridines

1989
Effects of PN 200-110, a new calcium antagonist, on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction elicited by selective alpha-adrenoceptor agonists and catecholamines in the pithed rat.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Catecholamines; Decerebrate State; Epinephrine; Imidazoles; Isradipine; Male; Norepinephrine; Oxadiazoles; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction

1985
Interaction between two calcium antagonists and two beta blockers in conscious rabbits: hemodynamic consequences of differing cardiodepressant properties.
    The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Consciousness; Drug Interactions; Hemodynamics; Humans; Isradipine; Oxadiazoles; Pindolol; Propranolol; Rabbits; Verapamil

1987
Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity.
    The Biochemical journal, 1995, Mar-01, Volume: 306 ( Pt 2)

    Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Hydrogen Bonding; Indoles; Isradipine; Ligands; Nifedipine; Orosomucoid; Progesterone; Propanolamines; Propranolol; Temperature; Thermodynamics; Warfarin

1995
Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smooth muscle cells.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:10

    Topics: Adrenergic beta-Antagonists; Amlodipine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Diuretics; Felodipine; Fibroblasts; Furosemide; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Isradipine; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Propranolol; Transcription, Genetic

1995