Page last updated: 2024-08-16

propranolol and fluorouracil

propranolol has been researched along with fluorouracil in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.35)	18.7374
1990's	3 (13.04)	18.2507
2000's	6 (26.09)	29.6817
2010's	10 (43.48)	24.3611
2020's	3 (13.04)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Topliss, JG; Yoshida, F	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Gao, Y; Guo, Q; Li, X; Liu, X; Sun, H; Wang, X; Wang, Y; Yang, Y; You, Q; Zeng, S; Zhang, S; Zhang, X; Zhao, L	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bian, J; Hu, M; Jiang, F; Li, X; Sun, H; Wu, Y; Yang, L; You, Q; Zhang, X	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Goto, M; Hamel, E; Hirazawa, S; Miura, Y; Nakagawa-Goto, K; Nakayoshi, T; Oda, A; Saito, Y; Taniguchi, Y; Tsurimoto, H; Yamashita, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Hirvonen, J; Paronen, P; Rytting, JH; Urtti, A	1
Imai, H; Tamai, G	1
Aksinenko, SG; Dygaĭ, AM; Gol'dberg, ED; Khlusov, IA	1
André, N; Carre, M; Ciccolini, J; Fanciullino, R; Giacometti, S; Kavallaris, M; Montero, MP; Pasquier, E; Pouchy, C; Serdjebi, C	1
Barathova, M; Belvoncikova, P; Csaderova, L; Fecikova, S; Grossmannova, K; Labudova, M; Pastorek, J; Puzderova, B	1

Reviews

1 review(s) available for propranolol and fluorouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

22 other study(ies) available for propranolol and fluorouracil

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Garcinia xanthones as orally active antitumor agents. Journal of medicinal chemistry, 2013, Jan-10, Volume: 56, Issue:1 Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Garcinia; Humans; Hydrogen-Ion Concentration; Male; Membranes, Artificial; Mice; Neoplasm Transplantation; Permeability; Solubility; Structure-Activity Relationship; Transplantation, Heterologous; Xanthones	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Novel natural-product-like caged xanthones with improved druglike properties and in vivo antitumor potency. Bioorganic & medicinal chemistry letters, 2015, Jun-15, Volume: 25, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Body Weight; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Drug Screening Assays, Antitumor; Garcinia; Humans; Mice; Structure-Activity Relationship; Transplantation, Heterologous; Xanthones	2015
Effects of substituent pattern on the intracellular target of antiproliferative benzo[b]thiophenyl chromone derivatives. European journal of medicinal chemistry, 2021, Oct-15, Volume: 222 Topics: Antineoplastic Agents; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured	2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Dodecyl N,N-dimethylamino acetate and azone enhance drug penetration across human, snake, and rabbit skin. Pharmaceutical research, 1991, Volume: 8, Issue:7 Topics: Aged; Animals; Azepines; Fluorouracil; Glycine; Humans; In Vitro Techniques; Indomethacin; Permeability; Propranolol; Rabbits; Skin Absorption; Snakes; Species Specificity	1991
Analysis of drug in tissue homogenates by high performance liquid chromatography with direct injection and column switching. Biomedical chromatography : BMC, 1989, Volume: 3, Issue:5 Topics: Animals; Cell-Free System; Chromatography, High Pressure Liquid; Fluorouracil; Kidney; Liver; Methotrexate; Mice; Myocardium; Organelles; Pharmaceutical Preparations; Procainamide; Propranolol	1989
[Significance of sympathetic-adrenal structures in hematopoiesis regulation in cytostatic myelodepression]. Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:4 Topics: Adrenal Glands; Animals; Bone Marrow Diseases; Cells, Cultured; Dihydroergotamine; Erythroid Precursor Cells; Fluorouracil; Ganglionic Blockers; Granulocytes; Hematopoiesis; Male; Mice; Mice, Inbred CBA; Propranolol; Quaternary Ammonium Compounds; Sympathetic Nervous System	1993
Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment. Oncotarget, 2011, Volume: 2, Issue:10 Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Endothelium, Vascular; Female; Fluorouracil; Humans; Mice; Mice, Nude; Paclitaxel; Propranolol	2011
Propranolol, Promising Chemosensitizer and Candidate for the Combined Therapy through Disruption of Tumor Microenvironment Homeostasis by Decreasing the Level of Carbonic Anhydrase IX. International journal of molecular sciences, 2023, Jul-04, Volume: 24, Issue:13 Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase IX; Cell Line, Tumor; Fluorouracil; Humans; Mice; Neoplasms; Propranolol; Tumor Microenvironment	2023