Page last updated: 2024-08-16

propranolol and clomipramine

propranolol has been researched along with clomipramine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's0 (0.00)18.2507
2000's8 (25.81)29.6817
2010's13 (41.94)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Delini-Stula, A; Radeke, E; Vassout, A1
Burgess, CD; Turner, P; Wadsworth, J1
Arnold, P; Brandt, CM; Fincker, JL; Rauscher, M; Schlienger, JL1
Balsara, JJ; Bapat, TR; Chandorkar, AG; Gada, VP; Nandal, NV1
Baruch, P; Jouvent, R; Simon, P1
Svensson, TH1
Mehendale, HM; Morita, T1
Luczynska, C; Wilson, K1
Marsden, CA; Stolz, JF1
Hentall, ID; Kurle, PJ; White, TR1

Reviews

3 review(s) available for propranolol and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effect of chronic treatment with tricyclic antidepressant drugs on identified brain noradrenergic and serotonergic neurons.
    Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Clonidine; Drug Interactions; Imipramine; Iontophoresis; Lysergic Acid Diethylamide; Male; Neurons; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Yohimbine

1980
The clinical significance of the effects of cigarette smoking on drug disposition.
    Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:7

    Topics: Acetaminophen; Antipyrine; Benzodiazepines; Chlorpromazine; Clomipramine; Codeine; Humans; Pharmaceutical Preparations; Phenacetin; Propranolol; Smoking; Theophylline; Warfarin

1983

Trials

1 trial(s) available for propranolol and clomipramine

ArticleYear
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol

1978

Other Studies

27 other study(ies) available for propranolol and clomipramine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Some aspects of the psychopharmacological activity of maprotiline (Ludiomil): effects of single and repeated treatments.
    The Journal of international medical research, 1978, Volume: 6, Issue:6

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Anthracenes; Behavior, Animal; Body Temperature; Clomipramine; Depression, Chemical; Escape Reaction; Haplorhini; Head; Imipramine; Maprotiline; Mice; Muscle Contraction; Phenobarbital; Propranolol; Rats; Reserpine; Shrews

1978
[Hemodynamic changes and variations of certain indexes of myocardial contractility with intravenous administration of clomipramine. Study in dogs anesthetized with barbiturates].
    Annales de cardiologie et d'angeiologie, 1975, Volume: 24, Issue:5

    Topics: Anesthesia, General; Animals; Clomipramine; Dibenzazepines; Dogs; Heart Rate; Hemodynamics; Injections, Intravenous; Myocardial Contraction; Pentobarbital; Propranolol

1975
Head-twitch response induced by ergometrine in mice: behavioural evidence for direct stimulation of central 5-hydroxytryptamine receptors by ergometrine.
    Psychopharmacology, 1986, Volume: 88, Issue:3

    Topics: Animals; Clomipramine; Cyproheptadine; Dose-Response Relationship, Drug; Ergonovine; Fenclonine; Fenfluramine; Male; Methysergide; Mice; p-Chloroamphetamine; Propranolol; Receptors, Serotonin; Stereotyped Behavior; Time Factors

1986
Manic episode after propranolol withdrawal.
    The American journal of psychiatry, 1986, Volume: 143, Issue:12

    Topics: Bipolar Disorder; Clomipramine; Depressive Disorder; Female; Humans; Middle Aged; Propranolol; Substance Withdrawal Syndrome; Tachycardia, Paroxysmal

1986
Drug-specificity in the perturbation of pulmonary disposition of serotonin in rabbit in vivo.
    Pharmacology, 1983, Volume: 27, Issue:5

    Topics: Animals; Chlorpromazine; Clomipramine; Imipramine; Lung; Male; Propranolol; Rabbits; Radioisotope Dilution Technique; Serotonin

1983
Withdrawal from chronic treatment with metergoline, dl-propranolol and amitriptyline enhances serotonin receptor mediated behaviour in the rat.
    European journal of pharmacology, 1982, Apr-08, Volume: 79, Issue:1-2

    Topics: Amitriptyline; Animals; Behavior, Animal; Clomipramine; Ergolines; Humans; Iprindole; Male; Metergoline; Methoxydimethyltryptamines; Motor Activity; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Substance Withdrawal Syndrome

1982
Correlations between serotonin level and single-cell firing in the rat's nucleus raphe magnus.
    Neuroscience, 2000, Volume: 95, Issue:4

    Topics: Animals; Clomipramine; Electrophysiology; Glutamic Acid; Methiothepin; Neurons; Nociceptors; Propranolol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

2000