Page last updated: 2024-08-16

propranolol and buspirone

propranolol has been researched along with buspirone in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's6 (15.79)18.2507
2000's10 (26.32)29.6817
2010's20 (52.63)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Dalvie, D; Loi, CM; Smith, DA1
Bojarski, AJ; Gunia, A; Marona, H; Pytka, K; Satała, G; Siwek, A; Szkaradek, N; Szneler, E; Waszkielewicz, AM1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Handzlik, J; Jankowska, A; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Kurczab, R; Nitek, W; Partyka, A; Satała, G; Siwek, A; Wesołowska, A; Żesławska, E1
Hashimoto, S; Kasahara, K; Nagatani, T; Takao, K1
Sprouse, JS1
Cervo, L; Grignaschi, G; Samanin, R1
Kitamura, Y; Nagatani, T; Watanabe, T1
Oriowo, MA1
Angrini, M; Leslie, JC; Shephard, RA1
Griffith, JC; Hudzik, TJ; Kinney, GG1
Baez, S; Jimenez, V; John, E; Lechin, F; Lechin, ME; Orozco, B; Pardey-Maldonado, B; van der Dijs, B1
Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM1
Haider, S; Haleem, DJ; Parveen, T; Samad, N1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX1
Inagaki, H; Kiyokawa, Y; Mori, Y; Takeuchi, Y1
da Silva, FC; de Oliveira Citó, Mdo C; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macêdo, DS; Moura, BA; Silva, MI; Woods, DJ1
Barbui, C; Bighelli, I; Breilmann, J; Castellazzi, M; Cipriani, A; Davies, SJ; Furukawa, TA; Girlanda, F; Guaiana, G; Koesters, M1
Gardner, I; Hatley, O; Jamei, M; Johnson, TN; Small, BG1

Reviews

2 review(s) available for propranolol and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Benzodiazepines versus placebo for panic disorder in adults.
    The Cochrane database of systematic reviews, 2019, Mar-28, Volume: 3

    Topics: Adult; Aged; Agoraphobia; Benzodiazepines; Buspirone; Humans; Imipramine; Middle Aged; Numbers Needed To Treat; Panic Disorder; Paroxetine; Patient Dropouts; Placebos; Propranolol; Randomized Controlled Trials as Topic; Remission Induction; Young Adult

2019

Trials

1 trial(s) available for propranolol and buspirone

ArticleYear
Enhancement of noradrenergic neural transmission: an effective therapy of myasthenia gravis: a report on 52 consecutive patients.
    Journal of medicine, 2000, Volume: 31, Issue:5-6

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Aged; Benzhydryl Compounds; Buspirone; Desipramine; Drug Therapy, Combination; Electromyography; Epinephrine; Female; Humans; Hydroxamic Acids; Male; Middle Aged; Modafinil; Myasthenia Gravis; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Phenylalanine; Platelet Aggregation; Propranolol; Serotonin; Serotonin Receptor Agonists; Sympathetic Nervous System; Tyrosine

2000

Other Studies

35 other study(ies) available for propranolol and buspirone

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Administration, Oral; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Half-Life; Kinetics; Piperazine; Piperazines; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Seizures; Xanthones

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT
    European journal of medicinal chemistry, 2018, Mar-10, Volume: 147

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Computer-Aided Design; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hydantoins; Male; Mice; Models, Molecular; Molecular Structure; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship

2018
Role of the central serotonergic system in the anticonflict effect of d-AP159.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Amygdala; Animals; Anti-Anxiety Agents; Buspirone; Chromatography, High Pressure Liquid; Conflict, Psychological; Electrochemistry; Flumazenil; Male; Microinjections; Propranolol; Pyridines; Rats; Rats, Wistar; Serotonin; Stereoisomerism; Thienopyridines

1992
Inhibition of dorsal raphe cell firing by MDL 73005EF, a novel 5-HT1A receptor ligand.
    European journal of pharmacology, 1991, Aug-29, Volume: 201, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dendrites; Dioxins; Electrophysiology; Evoked Potentials; In Vitro Techniques; Ligands; Male; Mesencephalon; Neurons; Propranolol; Raphe Nuclei; Rats; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes

1991
Different effects of intracerebral and systemic administration of buspirone in the forced swimming test: involvement of a metabolite.
    Life sciences, 1988, Volume: 43, Issue:25

    Topics: Adrenergic alpha-Antagonists; Animals; Buspirone; Dioxanes; Idazoxan; Injections, Subcutaneous; Male; Microinjections; Motor Activity; Propranolol; Raphe Nuclei; Rats; Rats, Inbred Strains; Reference Values; Restraint, Physical; Swimming

1988
Buspirone enhances head twitch behavior in mice.
    European journal of pharmacology, 1994, Mar-03, Volume: 253, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Buspirone; Drug Interactions; Male; Mice; Pargyline; Piperazines; Propranolol; Receptors, Serotonin; Serotonin Antagonists

1994
Neural inhibition in the rat lower esophageal sphincter: role of beta 3-adrenoceptor activation.
    General pharmacology, 1998, Volume: 30, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atropine; Buspirone; Carbachol; Electric Stimulation; Electrophysiology; Esophagogastric Junction; Ethanolamines; Male; Muscle Relaxation; Neural Inhibition; Nitric Oxide Synthase; Oxidopamine; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Serotonin Receptor Agonists; Tetrodotoxin; Vasoconstrictor Agents

1998
Effects of propranolol, buspirone, pCPA, reserpine, and chlordiazepoxide on open-field behavior.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Chlordiazepoxide; Defecation; Dose-Response Relationship, Drug; Fenclonine; Grooming; Injections, Intraperitoneal; Male; Motor Activity; Propranolol; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Agents; Tranquilizing Agents

1998
Antidepressant-like effects of 5-hydroxytryptamine1A receptor agonists on operant responding under a response duration differentiation schedule.
    Behavioural pharmacology, 1998, Volume: 9, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Analysis of Variance; Animals; Antidepressive Agents; Buspirone; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Inhibition, Psychological; Male; Propranolol; Rats; Rats, Long-Evans; Reaction Time; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists; Trazodone

1998
Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Behavior, Animal; Buspirone; Central Nervous System; Dexfenfluramine; Dextromethorphan; Fluoxetine; Male; Propranolol; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Syndrome

2005
Attenuation of restraint induced behavioral deficits by buspirone and propranolol in rats.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005, Volume: 15, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Buspirone; Drug Administration Schedule; Male; Propranolol; Rats; Rats, Wistar; Restraint, Physical; Serotonin Receptor Agonists

2005
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles

2008
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:4

    Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Models, Animal; Male; Midazolam; Phenelzine; Pheromones; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Reflex, Startle

2010
Reversal of cocaine withdrawal-induced anxiety by ondansetron, buspirone and propranolol.
    Behavioural brain research, 2012, May-16, Volume: 231, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Cocaine; Male; Motor Activity; Ondansetron; Propranolol; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2012
Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.
    Clinical pharmacology and therapeutics, 2023, Volume: 114, Issue:6

    Topics: Buspirone; Humans; Liver Cirrhosis; Midazolam; Models, Biological; Propranolol; Simvastatin

2023