Page last updated: 2024-08-16

propranolol and allopurinol

propranolol has been researched along with allopurinol in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.03)18.7374
1990's4 (10.81)18.2507
2000's9 (24.32)29.6817
2010's12 (32.43)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Lillehei, RC; MacCarter, DJ; Shatney, CH1
Christensen, LK; Hansen, JM1
Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL1
Jin, N; Packer, CS; Rhoades, RA1
Hininger, I; Nordmann, R; Ribiere, C1
Burghardt, B; Janero, DR; Lopez, R; Pittman, J1
Günther, K; Modersohn, D; Pankau, H; Scheider, D; Tronicke, E; Uhlich, C; Urbaszek, W1
Fleckenstein, L; Lasagna, L; Mazzullo, JM; Mundy, GR; Sundaresan, PR; Weintraub, M1
Jameson, S1
Iwaki, K; Yonetani, Y1
Badawy, AA1
Cybulska, I; Wasowska-Ciszek, T1
Dalipram, RA; Sobey, CG; Woodman, OL1
Abraham, E; Arcaroli, J; Shenkar, R1
Earnest, R; Goodman, MD; McGlone, E; Morris, MC; Singer, KE; Stevens-Topie, S; Wallen, TE1
Baucom, MR; Blakeman, TC; Goodman, MD; McGuire, JL; Schuster, RM; Singer, KE; Strilka, R; Wallen, TE; Youngs, J1

Reviews

2 review(s) available for propranolol and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
    Drugs, 1977, Volume: 13, Issue:1

    Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide

1977

Other Studies

35 other study(ies) available for propranolol and allopurinol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of allopurinol, propranolol and methylprednisolone on infarct size in experimental myocardial infarction.
    The American journal of cardiology, 1976, Mar-31, Volume: 37, Issue:4

    Topics: Allopurinol; Animals; Blood; Coronary Disease; Disease Models, Animal; Dogs; Heart; Hemodynamics; Hydrogen-Ion Concentration; Methylprednisolone; Myocardial Infarction; Myocardium; Oxygen; Propranolol

1976
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: Acetylcholine; Allopurinol; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nifedipine; Nitroglycerin; Propranolol

1992
Reactive oxygen-mediated contraction in pulmonary arterial smooth muscle: cellular mechanisms.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Phentolamine; Piperazines; Propranolol; Pulmonary Artery; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Verapamil; Xanthine Oxidase

1991
Disturbances in myocardial creatine kinase following ethanol administration to rats--trials of prevention by allopurinol, desferrioxamine and propranolol.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:3

    Topics: Alcohol Drinking; Alcoholic Intoxication; Allopurinol; Animals; Creatine Kinase; Deferoxamine; Dose-Response Relationship, Drug; Ethanol; Male; Myocardial Contraction; Myocardium; Propranolol; Rats; Rats, Inbred Strains

1991
Propranolol as xanthine oxidase inhibitor: implications for antioxidant activity.
    Life sciences, 1989, Volume: 44, Issue:21

    Topics: Allopurinol; Animals; Binding, Competitive; Cell Membrane; Free Radicals; Iron; Lipid Peroxidation; Liposomes; Membrane Lipids; Myocardium; Oxidation-Reduction; Propranolol; Rats; Rats, Inbred Strains; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1989
[Influence of metabolism-inhibiting as well as metabolism-accelerating and ionotropic drugs on myocardial survival time in the rat under anoxia conditions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Aug-15, Volume: 29, Issue:16

    Topics: Adrenergic beta-Antagonists; Allopurinol; Animals; Carnitine; Cell Survival; Digitoxin; Female; Heart; Hypoxia; Male; Metaproterenol; Myocardium; Norepinephrine; Practolol; Prednisolone; Propranolol; Rats; Strophanthins; Theophylline; Thiamine Pyrophosphate

1974
Current medical practice and the Food and Drug Administration. Some evidence for the existing gap.
    JAMA, 1974, Sep-23, Volume: 229, Issue:13

    Topics: Adult; Aged; Allopurinol; Angina Pectoris; Cephalexin; Child; Colchicine; Diuretics; Drug Labeling; Drug Prescriptions; Drug Therapy; Gout; Humans; Hypertension; Iron; Middle Aged; Physicians; Postoperative Complications; Propranolol; Retrospective Studies; United States; United States Food and Drug Administration; Uric Acid

1974
[Effects of Inderal in the treatment of uremic hypertension].
    Nordisk medicin, 1971, Nov-08, Volume: 86, Issue:44

    Topics: Adult; Allopurinol; Diabetic Coma; Drug Combinations; Drug Interactions; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranolol; Steroids; Uremia

1971
Catecholamine-induced hyperuricemia in eviscerated rats with functional hepatectomy.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:3

    Topics: Animals; Catecholamines; Hepatectomy; Isoproterenol; Liver; Male; Propranolol; Rats; Rats, Inbred Strains; Uric Acid; Xanthine Oxidase

1981
Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Allopurinol; Animals; Corticosterone; Dactinomycin; Glucose; Liver; Male; NAD; NADP; Propranolol; Rats; Starvation; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase

1981
[Treatment of arterial hypertension in old age].
    Kardiologia polska, 1980, Volume: 23, Issue:6

    Topics: Age Factors; Aged; Allopurinol; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Phthalazines; Propranolol

1980
Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.
    British journal of pharmacology, 1993, Volume: 108, Issue:2

    Topics: Allopurinol; Amlodipine; Anesthetics; Animals; Dogs; Endothelium, Vascular; Female; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Propranolol; Vasodilator Agents

1993
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animal Feed; Animals; Cyclic AMP Response Element-Binding Protein; Endotoxemia; Enzyme Activation; Hemorrhage; Injections, Intraperitoneal; Lung; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neutrophil Activation; NF-kappa B; Phentolamine; Propranolol; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tungsten; Xanthine Oxidase

2001
Postinjury treatments to make early tactical aeromedical evacuation practical for the brain after TBI.
    The journal of trauma and acute care surgery, 2021, 08-01, Volume: 91, Issue:2S Suppl 2

    Topics: Adenosine; Air Ambulances; Allopurinol; Amitriptyline; Animals; Brain; Brain Chemistry; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Mice; Mice, Inbred C57BL; Propranolol; Rotarod Performance Test

2021
Postinjury Treatment to Mitigate the Effects of Aeromedical Evacuation After Traumatic Brain Injury in a Porcine Model.
    The Journal of surgical research, 2022, Volume: 279

    Topics: Air Ambulances; Allopurinol; Animals; Brain Injuries, Traumatic; Humans; Interleukin-6; Mice; Propranolol; Saline Solution; Swine; Tranexamic Acid

2022