propranolol has been researched along with ajmaline in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (85.19) | 18.7374 |
| 1990's | 4 (7.41) | 18.2507 |
| 2000's | 1 (1.85) | 29.6817 |
| 2010's | 3 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mikhailov, AA; Sumarokov, AV | 1 |
| Doshchitsin, VL | 1 |
| Breithardt, G; Jochum, E; Kuhn, H; Seipel, L | 1 |
| Anshelevich, IuV; Beer, ET; Bekere, FA; Slaĭdyn', AK; Sorokina, TA | 1 |
| Ban, T | 1 |
| Förster, W; Mest, HJ; Winkler, J | 1 |
| Buttafarro, A; Casella, G; Freni, F; Gugliandolo, A; Pavia, L; Siracusano, L | 1 |
| Strauer, BE | 1 |
| Doenecke, VP | 1 |
| Hepp, A; Raff, U | 1 |
| Doenecke, P | 1 |
| Castellucci, A | 1 |
| Förster, W; Terhaag, B | 1 |
| Wellens, HJ | 1 |
| Araú, A; Bonhorst, D; Bordalo, A; De Azevedo, JG; Ferreira, M; Ferreira, R; Inês, L; Lacximy, I; Longo, A; Luis Martins, J; Melo, M; Nunes Diogo, A; Ribeiro, C; Sanches, C; Teixeira, J | 1 |
| Kawakami, M; Kimoto, S; Matsuda, S; Matsumura, S; Mroishige, E; Takeda, H; Ueda, M | 1 |
| Steinbach, K | 1 |
| Förster, W; Mest, HJ; Schrör, K; Terhaag, B | 1 |
| Gil, R; Kaźmierczak, J; Kornacewicz-Jach, Z; Zinka, E | 1 |
| Fomina, IG; Iankin, VV | 1 |
| Gil, R | 1 |
| Hashimoto, S; Kanazawa, T; Miura, M; Ono, Y | 1 |
| Turcu, E; Zamfir, C | 1 |
| Jouvet, M; Touche, M; Touche, S; Trouve, P | 1 |
| Breithardt, G; Loogen, F; Seipel, L | 1 |
| Strubelt, O; Zetler, G | 1 |
| Back, G; Strubelt, O; Uhl, E; Zetler, G | 1 |
| Gendenshteĭn, EI; Igol'nikova, LI; Kiseleva, RE | 1 |
| Kukes, VG; Mamedova, AD; Maziĭ, SA; Rozinov, IuI; Sivkov, II | 1 |
| Collignon, P; Kulbertus, H | 1 |
| Narula, OS | 1 |
| Brochier, M; Fauchier, JP; Raynaud, P; Raynaud, R | 1 |
| Binder, C; Wimmer, M | 1 |
| Förster, W; Mentz, P; Schmidt, R | 1 |
| Cetrullo, C | 1 |
| Fomina, IG; Golochevskaĭa, VS; Vasilenko, VKh | 1 |
| Arora, RB; Sundaresan, PR | 1 |
| Boissier, JR; Giudicelli, JF; Larno, S; Witchitz, S | 1 |
| Morita, M; Nagata, M; Sugimoto, J | 1 |
| De Thomatis, M | 1 |
| Hashiba, K | 1 |
| Kobayashi, K | 1 |
| Chuck, L; Parmley, WW; Tomoda, H | 1 |
| Bhatia, ML; Kaul, U; Mohan, JC | 1 |
| Golitsyn, SP; Grosu, AA; Smetnev, AS; Sokolov, SF | 1 |
| Perrenoud, JJ | 1 |
| Camous, JP; Crenesse, D; Guiran, JB; Lapalus, P; Varenne, A | 1 |
| Eichler, HG; Gouya, G; Schmetterer, L; Wolzt, M; Zanaschka, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
5 review(s) available for propranolol and ajmaline
| Article | Year |
|---|---|
[Treatment of extrasystole (ventricular and atrial extrasystoles)].
Topics: Adrenergic beta-Antagonists; Ajmaline; Aniline Compounds; Benzyl Compounds; Cardiac Complexes, Premature; Disopyramide; Hemodynamics; Humans; Imidazoles; Lidocaine; Phenytoin; Procainamide; Propanolamines; Propranolol; Quinidine | 1974 |
[Long-term treatment of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Ataxia; Electric Countershock; Gastrointestinal Diseases; Humans; Lidocaine; Long-Term Care; Phenytoin; Practolol; Procainamide; Propranolol; Psychotherapy; Quinidine; Time Factors | 1974 |
Wolff-Parkinson-White Syndrome. A review.
Topics: Adult; Ajmaline; Atropine; Cardiac Catheterization; Digitalis Glycosides; Electric Stimulation; Electrocardiography; Heart; Heart Atria; Heart Conduction System; Humans; Male; Methods; Pacemaker, Artificial; Procainamide; Propranolol; Quinidine; Tachycardia; Vagus Nerve; Wolff-Parkinson-White Syndrome | 1973 |
[Progress in the treatment of arrhythmia].
Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Electric Countershock; Electrocardiography; Humans; Pacemaker, Artificial; Propranolol; Quinidine; Wolff-Parkinson-White Syndrome | 1971 |
[Utilization of anti-arrhythmic drugs].
Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digitalis Glycosides; Dose-Response Relationship, Drug; Heart Conduction System; Humans; Kidney; Mexiletine; Myocardial Contraction; Propranolol; Ventricular Fibrillation; Verapamil; Wolff-Parkinson-White Syndrome | 1980 |
4 trial(s) available for propranolol and ajmaline
| Article | Year |
|---|---|
[The effect of some antiarrhythmic drugs on systolic time intervals in normal subjects (author's transl)].
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Disopyramide; Humans; Myocardial Contraction; Propiophenones; Propranolol; Quinidine; Systole; Time Factors | 1978 |
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil | 1992 |
[Ventricular fibrillation at the acute phase of myocardial infarction: prognosis after resuscitation].
Topics: Adult; Ajmaline; Angina Pectoris; Clinical Trials as Topic; Diagnosis, Differential; Electric Countershock; Female; Heart Arrest; Humans; Intensive Care Units; Lidocaine; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Pacemaker, Artificial; Prognosis; Propranolol; Resuscitation; Ventricular Fibrillation | 1973 |
Is the ECG measure RSh a promising technique for detecting class I antiarrhythmic drug action in men?
Topics: Adenosine; Adult; Ajmaline; Anti-Arrhythmia Agents; Atropine; Disopyramide; Electrocardiography; Humans; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Propranolol; Reproducibility of Results; Sodium Channel Blockers; Verapamil | 1995 |
45 other study(ies) available for propranolol and ajmaline
| Article | Year |
|---|---|
[Certain practical problems of recognition and treatment of cardiac rhythm disorders].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Cardiac Glycosides; Electric Countershock; Electrocardiography; Humans; Lidocaine; Pacemaker, Artificial; Procainamide; Propranolol; Quinidine; Reserpine; Tachycardia, Paroxysmal | 1975 |
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil | 1975 |
[Effectiveness of treatment of paroxysms of auricular flutter].
Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Atrial Flutter; Electric Countershock; Humans; Middle Aged; Potassium Magnesium Aspartate; Procainamide; Propranolol; Strophanthins; Thiamine Pyrophosphate; Verapamil | 1979 |
A kinetic study of effects of propranolol and N-propylajmaline on the rate of rise of action potential in guinea pig papillary muscles.
Topics: Action Potentials; Ajmaline; Animals; Depression, Chemical; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Papillary Muscles; Propranolol | 1977 |
The antiarrhythmic effect of prostaglandin E2 on catecholamine-induced arrhythmias.
Topics: Ajmaline; Animals; Arrhythmias, Cardiac; Catecholamines; Female; Guinea Pigs; Male; Propranolol; Prostaglandins E | 1977 |
[Comparative study of the effect of some drugs on A-V conduction by recording of the His electrocardiogram].
Topics: Adult; Aged; Ajmaline; Bundle-Branch Block; Digitalis Glycosides; Electrocardiography; Heart Conduction System; Humans; Male; Middle Aged; Propranolol; Verapamil; Wolff-Parkinson-White Syndrome | 1978 |
[Comparative studies on the contractile and hemodynamic effects of antiarrhythmic agents (lidocaine, diphenylhydantoin, ajmaline) (author's transl)].
Topics: Ajmaline; Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Cats; Dose-Response Relationship, Drug; Heart Ventricles; Hemodynamics; Humans; In Vitro Techniques; Lidocaine; Myocardial Contraction; Phenytoin; Propranolol | 1976 |
[Myocardial excitability under the influence of digitalis glycosides and anti-arrhythmia agent].
Topics: Ajmaline; Anti-Arrhythmia Agents; Digitalis Glycosides; Digoxin; Heart Conduction System; Humans; Lidocaine; Myocardial Contraction; Phenytoin; Procainamide; Propranolol; Refractory Period, Electrophysiological; Stimulation, Chemical; Verapamil | 1977 |
[The influence of antiarrhythmic drugs on the exercise-ecg (author's transl)].
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Exercise Test; Heart Rate; Humans; Methods; Phenytoin; Propranolol; Quinidine; Verapamil | 1977 |
[Influence of cardiac agents on the diastolic irritability of the ventricular myocardium. Consequences for pacemaker therapy].
Topics: Adult; Aged; Ajmaline; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Dogs; Female; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Contraction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Stimulation, Chemical; Verapamil | 1976 |
Metabolic effects of bunaftine, a new antiarrhythmic agent: comparison with quinidine, ajmaline, procainamide, xylocaine and propranolol.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Basal Metabolism; Butylamines; Glycolysis; Lidocaine; Male; Myocardium; Naphthalenes; Oxygen Consumption; Procainamide; Propranolol; Quinidine; Rabbits; Rats | 1976 |
[Antiarrhythmic, cardiovascular and toxic actions of N,N'-bis-[3-(2'-ethoxyphenoxy)-2-hydroxypropyl]-ethlenediamine (Falirytmin) as compared to propranolol, quinidine and ajmaline].
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barium; Blood Pressure; Cats; Dogs; Ethylenediamines; Hemodynamics; In Vitro Techniques; Propranolol; Quinidine; Rabbits; Rats; Strophanthins; Time Factors | 1976 |
Effect of drugs in the wolff-parkinson-white syndrome.
Topics: Ajmaline; Digitalis Glycosides; Electric Stimulation; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Verapamil; Wolff-Parkinson-White Syndrome | 1975 |
Mechanism of action of antidysrhythmic drugs on ventricular conduction as studied with intramural electrodes.
Topics: Ajmaline; Animals; Disopyramide; Dogs; Electrocardiography; Heart Conduction System; Hydroxyzine; Lidocaine; Oxprenolol; Phenytoin; Propranolol; Purkinje Fibers; Quinidine; Verapamil | 1975 |
Antiarrhythmic effect of aprindine on several types of ventricular arrhythmias.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Aprindine; Cats; Dogs; Epinephrine; Female; Guinea Pigs; Heart Rate; Heart Ventricles; Indenes; Ischemia; Lidocaine; Male; Ouabain; Procainamide; Propranolol; Quinidine | 1975 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Humans; Isoproterenol; Lidocaine; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia; Verapamil | 1975 |
[Antiarrhythmic, cardiovascular and toxic effects of 4-[3'-diethylamino-2'-hydroxypropyl]-ajmaline (Tachmalcor) in comparison with ajmaline and propranolol].
Topics: Administration, Oral; Ajmaline; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cats; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Heart Conduction System; Heart Rate; Hemodynamics; Injections, Intravenous; Lethal Dose 50; Propranolol; Rabbits; Rats | 1976 |
[Mitral valve prolapse. Atrial stimulation, ajmaline test and "pharmacological denervation" in the evaluation of ventricular repolarization].
Topics: Adolescent; Adult; Ajmaline; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart; Heart Atria; Heart Ventricles; Humans; Male; Middle Aged; Mitral Valve Prolapse; Propranolol | 1992 |
[Evaluation of the activity of the heart conduction system with special reference to the sinoatrial node automatism in patients with mitral valve prolapse syndrome].
Topics: Action Potentials; Adolescent; Adult; Ajmaline; Arrhythmia, Sinus; Atrial Function, Right; Atropine; Female; Heart Conduction System; Humans; Male; Middle Aged; Mitral Valve Prolapse; Propranolol; Sinoatrial Node; Tachycardia, Supraventricular; Ventricular Function, Right | 1991 |
[Panel discussion: Evaluation of the antiarrhythmic drugs and current problems associated with their use in clinical practice (author's transl)].
Topics: Administration, Oral; Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Diethylamines; Disopyramide; Dogs; Heart Ventricles; Humans; Indans; Injections; Injections, Intravenous; Myocardial Infarction; Practolol; Procainamide; Propranolol; Quinidine; Tachycardia | 1974 |
[Treatment of paroxysmal disorders of cardiac rhythm].
Topics: Acetanilides; Adrenergic beta-Antagonists; Ajmaline; Amino Alcohols; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bretylium Compounds; Digitalis Glycosides; Electric Countershock; Humans; Lidocaine; Phenytoin; Propranolol; Propylamines; Pyridines; Quinidine; Tachycardia, Paroxysmal; Ventricular Fibrillation | 1972 |
[Symposium on anti-arrhythmic drugs of the Swedish Society of Cardiology].
Topics: Adrenergic beta-Agonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis; Electrocardiography; Heart; Hemodynamics; Humans; Lidocaine; Phenytoin; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Quinidine; Tachycardia | 1973 |
Actions of antiarrhythmic drugs on refractory period and contractility of isolated rat and guinea-pig atria.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Ethers; Ethylamines; Glycerol; Guinea Pigs; Heart Atria; Lidocaine; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Rats; Sparteine; Verapamil | 1971 |
Cardiac output, heart rate, and blood pressure as influenced by equi-antiarrhythmic doses of eight antifibrillatory agents.
Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Capillary Resistance; Cardiac Output; Cardiac Volume; Ethers; Ethylamines; Glycerol; Heart Rate; Lidocaine; Male; Phenytoin; Procainamide; Propranolol; Quinidine; Rats; Respiration, Artificial; Sparteine | 1971 |
[Effect of quinidine, ajmaline and anapriline on certain metabolic processes in the heart conduction system].
Topics: Ajmaline; Animals; Cats; Energy Metabolism; Female; Glycogen; Heart Conduction System; Histocytochemistry; Male; Myocardium; Phosphoric Monoester Hydrolases; Propranolol; Quinidine; RNA; Succinate Dehydrogenase; Sulfhydryl Compounds | 1974 |
[Certain problems of antiarrhythmia therapy in myocardial infarct].
Topics: Administration, Oral; Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Male; Middle Aged; Myocardial Infarction; Procainamide; Propranolol; Quinidine | 1974 |
[Action of anti-arrhythmia agents on intracardiac conduction].
Topics: Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Benzofurans; Bundle of His; Cardiac Catheterization; Depression, Chemical; Diethylamines; Dogs; Electrocardiography; Heart Conduction System; Indans; Iodobenzoates; Lidocaine; Lidoflazine; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1974 |
[Adverse effects of recent ventricular anti-arrhythmia drug].
Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Synergism; Electrocardiography; Heart Arrest; Heart Ventricles; Humans; Hypotension; Lidocaine; Phenytoin; Propranolol; Tosyl Compounds | 1972 |
[Intoxication with antiarrythmica (author's transl)].
Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child, Preschool; Electrocardiography; Humans; Hypotension; Lidocaine; Male; Metaproterenol; Muscle Cramp; Paralysis; Phenytoin; Propranolol; Quinidine; Reserpine; Vertigo | 1972 |
[The effect of cardiovascular agents on amino acid aryl amidase].
Topics: Ajmaline; Alanine; Amides; Aminohydrolases; Animals; Anti-Arrhythmia Agents; Azo Compounds; Cardiac Glycosides; Humans; Propranolol; Quinidine; Rabbits; Strophanthins | 1973 |
[Arrhythmias during anesthesia: clinical aspects and therapy].
Topics: Ajmaline; Anesthesia; Arrhythmias, Cardiac; Humans; Practolol; Propranolol | 1973 |
[Clinical aspects and treatment of paroxysmal forms of cardiac rhythm disorders].
Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Injections, Intravenous; Male; Middle Aged; Procainamide; Propranolol | 1973 |
Studies on peruvoside. 2. Relative effectiveness of propranolol, diphenylhydantoin & ajmaline in peruvoside induced tachyarrhythmias in dogs.
Topics: Ajmaline; Animals; Cardiac Glycosides; Dogs; Female; Male; Methods; Phenytoin; Propranolol; Tachycardia | 1973 |
Experimental evaluation of antiarrhythmic drugs in the guinea pig.
Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Guinea Pigs; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine; Strophanthins; Verapamil | 1973 |
Comparative studies on the pharmacological actions of anti-arrhythmics in isolated guinea-pig atria.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Benzyl Compounds; Cocaine; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Lidocaine; Male; Methyl Ethers; Phenytoin; Piperazines; Procainamide; Propranolol; Quinidine | 1973 |
[Medical treatment of disturbances of the heart rhythm].
Topics: Ajmaline; Amiodarone; Arrhythmias, Cardiac; Digoxin; Disopyramide; Humans; Procainamide; Propranolol | 1973 |
[Experimental studies on the mechanism of digitalis and several antiarrhythmic agents--a consideration on roles of the central nervous system].
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Brain; Cerebral Cortex; Digitalis Glycosides; Electrocardiography; Electroencephalography; Hypothalamus; Mesencephalon; Phenobarbital; Phenytoin; Procainamide; Propranolol; Rabbits; Thalamus | 1972 |
Comparative myocardial depressant effects of lidocaine, ajmalin, propranolol and quinidine.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Cats; Heart Atria; Heart Ventricles; In Vitro Techniques; Lidocaine; Papillary Muscles; Plants, Medicinal; Propranolol; Quinidine; Rauwolfia | 1972 |
Acute effects of anti-arrhythmic drugs on cardiac pacing threshold.
Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrophysiology; Female; Heart; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Propranolol; Verapamil | 1984 |
[Method of evaluating antiarrhythmic therapy in patients with paroxysms of supraventricular tachycardia].
Topics: Adolescent; Adult; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Evaluation; Electric Stimulation; Female; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Verapamil | 1984 |
Effects in conscious dogs of ajmaline, propranolol, amiodarone and verapamil on right ventricular anodal strength-interval curves.
Topics: Ajmaline; Amiodarone; Animals; Anti-Arrhythmia Agents; Dogs; Myocardial Contraction; Propranolol; Verapamil | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |