propofol has been researched along with pregnanolone in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (22.22) | 18.7374 |
| 1990's | 17 (47.22) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, A; Boyd, AC; Byford, A; Campbell, AC; Gemmell, DK; Hamilton, NM; Hill, DR; Hill-Venning, C; Lambert, JJ; Maidment, MS; Marshall, RJ; May, V; Peters, JA; Rees, DC; Stevenson, D; Sundaram, H | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Dundee, JW | 1 |
| Desmonts, JM | 1 |
| Carl, P; Høgskilde, S; Sørensen, MB; Wagner, J | 1 |
| Dye, A; Prys-Roberts, C; Sear, JW | 1 |
| Sear, JW | 1 |
| Bretz, C; Doenicke, A; Haegler, H; Kugler, J; Suttmann, H; Wörschhauser, J | 1 |
| Clarke, RS | 1 |
| Prys-Roberts, C | 1 |
| Deruyter, HA; Marcus, MA; Van Aken, H; Van de Velde, MA; Wouters, PF | 1 |
| Jewkes, C; Sear, JW; Wanigasekera, V | 1 |
| Haasio, J; Kallela, H; Korttila, K | 1 |
| Muller, P; Van Aken, H; Van Hemelrijck, J; White, PF | 1 |
| Mulier, JP; Van Aken, H | 1 |
| Drummond, GB; Spens, HJ; Wraith, PK | 1 |
| Bennett, PJ; Simmonds, MA | 1 |
| Simmonds, MA; Zhong, Y | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Beskow, A; Werner, O; Westrin, P | 1 |
| Belelli, D; Hill-Venning, C; Lambert, JJ; Peters, JA | 1 |
| Davies, PA; Hales, TG; Kirkness, EF | 1 |
| Cooper, GM; Hutton, P; Malins, AF; Rasanayagam, SR; Whyte, JA | 1 |
| Qi, J; Tang, J; Wang, B; Wender, RH; White, PF | 1 |
| Simmonds, MA; Sooksawate, T | 2 |
| Belelli, D; Lambert, JJ; Peters, JA; Pistis, M | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Elmér, E; Hansson, MJ; Hasegawa, E; Kasuya, K; Månsson, R; Morota, S; Omi, A; Shimazu, M; Uchino, H; Yanagi, S | 1 |
| Bell, SV; Jenkins, A; Williams, CA | 1 |
| Antkowiak, B; Balk, M; Drexler, B | 1 |
| Akk, G; Burbridge, AB; Germann, AL; Pierce, SR; Steinbach, JH | 1 |
| Akk, G; Germann, AL; Pierce, SR; Senneff, TC | 1 |
| Antkowiak, B; Drexler, B; Grasshoff, C; Grenz, J | 1 |
| Goodchild, CS; Serrao, JM | 1 |
2 review(s) available for propofol and pregnanolone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
General kinetic and dynamic principles and their application to continuous infusion anaesthesia.
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Animals; Etomidate; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Kinetics; Mathematics; Methohexital; Middle Aged; Models, Biological; Phenols; Pregnanolone; Propofol; Rats; Thiopental | 1983 |
9 trial(s) available for propofol and pregnanolone
| Article | Year |
|---|---|
Hepatic function after anaesthesia for major vascular reconstructive surgery.
Topics: Aged; Alfaxalone Alfadolone Mixture; Anesthesia, General; Aspartate Aminotransferases; Bilirubin; gamma-Glutamyltransferase; Halothane; Humans; L-Lactate Dehydrogenase; Liver; Middle Aged; Ornithine Carbamoyltransferase; Phenols; Pregnanolone; Propofol; Vascular Surgical Procedures | 1983 |
Hemodynamic effects during induction, laryngoscopy, and intubation with eltanolone (5 beta-pregnanolone) or propofol. A study in ASA I and II patients.
Topics: Anesthesia; Blood Pressure; Cardiac Output; Double-Blind Method; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Preanesthetic Medication; Pregnanolone; Propofol; Prospective Studies; Temazepam; Vascular Resistance | 1995 |
Comparison of eltanolone and propofol in anesthesia for termination of pregnancy.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Obstetrical; Female; Humans; Middle Aged; Pregnancy; Pregnanolone; Propofol | 1994 |
Relative potency of eltanolone, propofol, and thiopental for induction of anesthesia.
Topics: Adolescent; Adult; Anesthesia, General; Blood Pressure; Female; Heart Rate; Humans; Male; Middle Aged; Pregnanolone; Propofol; Thiopental | 1994 |
Comparison of eltanolone and propofol on a pressure-volume analysis of the heart.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Blood Volume; Cardiac Volume; Depression, Chemical; Echocardiography, Transesophageal; Fat Emulsions, Intravenous; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Myocardial Contraction; Pregnanolone; Propofol; Radial Artery; Respiration, Artificial; Ventricular Function, Left; Ventricular Pressure | 1996 |
Changes in chest wall compartment volumes on induction of anaesthesia with eltanolone, propofol and thiopentone.
Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anthropometry; Female; Functional Residual Capacity; Humans; Male; Middle Aged; Plethysmography; Pregnanolone; Propofol; Thiopental; Thorax | 1996 |
A comparison of eltanolone and propofol anaesthesia for minor gynaecological surgery.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Pressure; Female; Genitalia, Female; Humans; Middle Aged; Minor Surgical Procedures; Pregnanolone; Propofol | 1997 |
Eltanolone as an alternative to propofol for ambulatory anesthesia.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthetics, Intravenous; Double-Blind Method; Female; Humans; Male; Middle Aged; Pregnanolone; Propofol | 1997 |
Alfaxalone anaesthesia increases brain derived neurotrophic factor levels and preserves postoperative cognition by activating pregnane-X receptors: an in vitro study and a double blind randomised controlled trial.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Australia; Brain-Derived Neurotrophic Factor; Cognition; Double-Blind Method; Humans; Pregnanolone; Propofol; Prospective Studies; Sevoflurane | 2022 |
25 other study(ies) available for propofol and pregnanolone
| Article | Year |
|---|---|
Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors.
Topics: Anesthesia; Anesthetics; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin System; Electric Conductivity; Electrophysiology; Male; Mice; Molecular Structure; Morpholines; Pregnanediones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solubility; Structure-Activity Relationship; Water | 1997 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
New i.v. anaesthetics.
Topics: Anesthesia, Intravenous; Anesthetics; Animals; Benzodiazepines; Etomidate; Humans; Kinetics; Midazolam; Phenols; Pregnanolone; Propofol | 1979 |
[Intravenous anesthetics: what future?].
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Benzodiazepines; Etomidate; Humans; Midazolam; Phenols; Polyethylene Glycols; Pregnanolone; Propofol | 1985 |
Anaesthetic properties of pregnanolone emulsion. A comparison with alphaxolone/alphadolone, propofol, thiopentone and midazolam in a rat model.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Animals; Drug Evaluation, Preclinical; Emulsions; Female; Male; Midazolam; Phenols; Pregnanes; Pregnanolone; Propofol; Rats; Rats, Inbred Lew; Thiopental | 1987 |
[Perspective on future developments of intravenous hypnotic agents].
Topics: Anesthesia, Intravenous; Chemical Phenomena; Chemistry; Etomidate; Humans; Hypnotics and Sedatives; Phenols; Pregnanolone; Propofol | 1981 |
Comparative merits of intravenous anesthetic agents for outpatient surgery.
Topics: Alfaxalone Alfadolone Mixture; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics; Drug Hypersensitivity; Etomidate; Humans; Ketamine; Methohexital; Phenols; Pregnanolone; Propanidid; Propofol; Thiopental | 1982 |
Cardiovascular effects of continuous intravenous anaesthesia compared with those of inhalational anaesthesia.
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Cardiovascular System; Etomidate; Halothane; Humans; Methohexital; Middle Aged; Nitrous Oxide; Phenols; Pregnanolone; Propofol | 1982 |
Hemodynamic changes during induction of anesthesia with eltanolone and propofol in dogs.
Topics: Anesthesia, Intravenous; Animals; Atrial Function, Left; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypnotics and Sedatives; Liver Circulation; Male; Portal Vein; Pregnanolone; Propofol; Regional Blood Flow; Renal Circulation; Vascular Resistance; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure | 1995 |
The influence of membrane cholesterol on the GABAA receptor.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Flunitrazepam; GABA Agents; Liposomes; Male; Muscimol; Pregnanolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1996 |
Pharmacological characterisation of multiple components in the enhancement by pregnanolone and propofol of [3H]flunitrazepam binding to GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Bicuculline; Flunitrazepam; GABA Agonists; GABA Modulators; In Vitro Techniques; Male; Muscimol; Pregnanolone; Progesterone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Intravenous induction of general anaesthesia with eltanolone in children 6-15 years of age.
Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Child; Drug Evaluation; Female; Humans; Male; Pilot Projects; Pregnanolone; Propofol; Thiopental | 1997 |
Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor.
Topics: Anesthetics, Intravenous; Animals; Etomidate; Humans; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1997 |
Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.
Topics: Anesthetics, General; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; gamma-Aminobutyric Acid; Humans; Pentobarbital; Pregnanolone; Propofol; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sulfur Radioisotopes | 1997 |
Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones.
Topics: Animals; Cholesterol; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; Liposomes; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pregnanediones; Pregnanolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Steroids; Synapses; Synaptic Membranes | 1998 |
The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors.
Topics: Anesthetics; Animals; Drug Interactions; Electric Conductivity; Etomidate; Female; gamma-Aminobutyric Acid; Glycine; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 1999 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders--specificity vs. toxicity.
Topics: Amino Acid Isomerases; Animals; Boron Compounds; Brain; Brain Diseases; Calcium; Cyclophilins; Dose-Response Relationship, Drug; Humans; Male; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Peptidyl-Prolyl Isomerase F; Pregnanolone; Progesterone; Propofol; Rats; Rats, Wistar; Tamoxifen; Trifluoperazine; Trimetazidine | 2009 |
A residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Anesthetics; Animals; Cell Line; gamma-Aminobutyric Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Pregnanolone; Propofol; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, GABA-A; Sequence Alignment | 2010 |
Synergistic Modulation of γ-Aminobutyric Acid Type A Receptor-Mediated Synaptic Inhibition in Cortical Networks by Allopregnanolone and Propofol.
Topics: Anesthetics; Animals; Drug Synergism; Female; GABA Modulators; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neocortex; Nerve Net; Neural Inhibition; Pregnanolone; Propofol; Receptors, GABA-A; Synaptic Transmission | 2016 |
Steady-State Activation and Modulation of the Concatemeric
Topics: Allosteric Regulation; Animals; beta-Alanine; GABA-A Receptor Agonists; Multiprotein Complexes; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus laevis | 2019 |
Steady-state activation of the high-affinity isoform of the α4β2δ GABA
Topics: Animals; GABA-A Receptor Agonists; Humans; Kinetics; Pregnanolone; Propofol; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2019 |
Allopregnanolone Enhances GABAergic Inhibition in Spinal Motor Networks.
Topics: Action Potentials; Animals; Cells, Cultured; gamma-Aminobutyric Acid; Mice; Motor Neurons; Neuromuscular Junction; Pregnanolone; Propofol; Receptors, GABA-A; Spinal Cord | 2020 |