Page last updated: 2024-08-16

propofol and metoclopramide

propofol has been researched along with metoclopramide in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (28.57)18.2507
2000's23 (54.76)29.6817
2010's7 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fee, JP; Ganta, R1
Campbell, NN; Thomas, AD1
Mecklem, DW1
Appadu, BL; Lambert, DG; Strange, PG1
Bevan, JC; Blackstock, D; Merrick, PM; Montgomery, CJ; Popovic, V; Reimer, EJ1
Ali, PB; Graham, SG1
Lacroix, G; Lessard, MR; Trépanier, CA1
Martin, TM; Rose, JB1
Watts, SA1
Buil, JA; Castaño, J; Castillo, J; Escolano, F; Santiveri, X1
Chhipa, JH; Page, VJ1
Chang, DP; Hwang, MH; Liaw, WJ; Pang, WW1
Fujii, Y; Numazaki, M2
Ideuchi, N; Kemmotsu, O; Morimoto, Y; Okuyama, A; Sasaki, S1
Fujii, Y; Kobayashi, N; Tanaka, H2
Hirayama, T; Ishii, F; Ogata, H; Yago, K1
Hammas, B; Thörn, SE; Wattwil, M1
Murphy, EJ1
Fujii, Y; Nakano, M1
Fujii, Y; Uemura, A1
Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X1
Bautista, AP; Ferreira, TA; Molíns, N; Rama-Maceiras, P; Rey, T; Sanduende, Y1
Fujii, Y; Nakayama, M2
Fujii, Y; Shiga, Y1
Ahmed, SA; Herazo, L; Iyer, C; Joshi, GP; Lenkovsky, F; Markin, V; Robertson, BD; Ross, L1
Fujii, Y; Itakura, M2
Akçabay, M; Arslan, M; Ozsoylar, O; Sarigüney, D; Unal, Y1
Fujii, Y1
Chaudhary, K; Gogia, AR; Gupta, P1
Aktay, M; Ozlü, O; Polat, R1
Catré, D; Duque, M; Ribeiro, S; Santos, L1
Afful, AP; Anabah, TW; Buunaaim, ADB; Kampo, S; Mohammed, S; Ntim, M1

Reviews

4 review(s) available for propofol and metoclopramide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evaluation of the effective drugs for the prevention of nausea and vomiting induced by morphine used for postoperative pain: a quantitative systematic review.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:2

    Topics: Antiemetics; Dexamethasone; Droperidol; Humans; Metoclopramide; Morphine; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Randomized Controlled Trials as Topic

2001
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; Metoclopramide; Midazolam; Middle Aged; Molecular Weight; Pain; Premedication; Propofol; Prospective Studies; Triglycerides

2004
Prevention of nausea and vomiting during termination of pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2010, Volume: 111, Issue:1

    Topics: Abortion, Therapeutic; Antiemetics; Benzimidazoles; Dexamethasone; Dilatation and Curettage; Droperidol; Drug Therapy, Combination; Female; Humans; Hydroxyzine; Metoclopramide; Ondansetron; Postoperative Nausea and Vomiting; Pregnancy; Propofol; Randomized Controlled Trials as Topic

2010

Trials

29 trial(s) available for propofol and metoclopramide

ArticleYear
Pain on injection of propofol: comparison of lignocaine with metoclopramide.
    British journal of anaesthesia, 1992, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Preanesthetic Medication; Propofol; Thrombophlebitis

1992
Does propofol have an anti-emetic effect? A prospective study of the anti-emetic effect of propofol following laparoscopy.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:3

    Topics: Adult; Antiemetics; Blood Pressure; Female; Humans; Laparoscopy; Metoclopramide; Nausea; Postoperative Complications; Propofol; Prospective Studies; Vomiting

1991
Propofol injection pain: comparing the addition of lignocaine or metoclopramide.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Blood Pressure; Extrapyramidal Tracts; Female; Heart Rate; Humans; Incidence; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Nausea; Pain; Propofol; Prospective Studies; Pulse; Single-Blind Method; Vomiting

1994
Propofol anaesthesia reduces early postoperative emesis after paediatric strabismus surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:10

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Child, Preschool; Female; Halothane; Humans; Incidence; Length of Stay; Male; Mental Recall; Metoclopramide; Nitrous Oxide; Postoperative Complications; Propofol; Strabismus; Thiopental; Vomiting

1993
Metoclopramide and prochlorperazine do not decrease propofol hypnotic requirements.
    Anaesthesia, 1995, Volume: 50, Issue:11

    Topics: Adult; Anesthetics, Intravenous; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Metoclopramide; Prochlorperazine; Propofol

1995
Treatment of postoperative nausea and vomiting: comparison of propofol, droperidol and metoclopramide.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:2

    Topics: Adult; Antiemetics; Double-Blind Method; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Postoperative Complications; Propofol; Prospective Studies; Vomiting

1996
Posttonsillectomy vomiting. Ondansetron or metoclopramide during paediatric tonsillectomy: are two doses better than one?
    Paediatric anaesthesia, 1996, Volume: 6, Issue:1

    Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Antiemetics; Child; Child, Preschool; Double-Blind Method; Female; Humans; Incidence; Injections, Intravenous; Isoflurane; Male; Metoclopramide; Ondansetron; Placebos; Postoperative Complications; Premedication; Propofol; Prospective Studies; Tonsillectomy; Vomiting

1996
A randomized double-blinded comparison of metoclopramide, ondansetron and cyclizine in day-case laparoscopy.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Antiemetics; Cyclizine; Female; Genitalia, Female; Humans; Incidence; Injections, Intravenous; Isoflurane; Laparoscopy; Metoclopramide; Nausea; Ondansetron; Pilot Projects; Postoperative Complications; Premedication; Propofol; Vomiting

1996
Metoclopramide reduces the induction dose of propofol.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Antiemetics; Dopamine Antagonists; Double-Blind Method; Drug Interactions; Female; Humans; Male; Metoclopramide; Propofol

1997
Pain on injection of propofol: the mitigating influence of metoclopramide using different techniques.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1

    Topics: Adult; Analgesics; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Chi-Square Distribution; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Humans; Incidence; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Pain; Pain Measurement; Placebos; Propofol; Sodium Chloride; Time Factors; Tourniquets

1999
Subhypnotic dose of propofol for the prevention of nausea and vomiting during spinal anaesthesia for caesarean section.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Incidence; Injections, Intravenous; Intraoperative Care; Lidocaine; Metoclopramide; Placebos; Postoperative Nausea and Vomiting; Pregnancy; Propofol; Safety

2000
Prevention of postoperative nausea and vomiting with antiemetics in patients undergoing middle ear surgery: comparison of a small dose of propofol with droperidol or metoclopramide.
    Archives of otolaryngology--head & neck surgery, 2001, Volume: 127, Issue:1

    Topics: Adult; Analysis of Variance; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Droperidol; Ear, Middle; Female; Humans; Male; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Propofol

2001
Small doses of propofol, droperidol, and metoclopramide for the prevention of postoperative nausea and vomiting after thyroidectomy.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2001, Volume: 124, Issue:3

    Topics: Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Droperidol; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Thyroidectomy

2001
Superior prolonged antiemetic prophylaxis with a four-drug multimodal regimen - comparison with propofol or placebo.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:3

    Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anesthesia, General; Antiemetics; Breast; Dexamethasone; Droperidol; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Metoclopramide; Middle Aged; Ondansetron; Postoperative Nausea and Vomiting; Propofol

2002
Reduction of emetic symptoms during cesarean delivery with antiemetics: propofol at subhypnotic dose versus traditional antiemetics.
    Journal of clinical anesthesia, 2003, Volume: 15, Issue:6

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Double-Blind Method; Droperidol; Female; Humans; Metoclopramide; Postoperative Nausea and Vomiting; Pregnancy; Propofol

2003
Prevention of nausea and vomiting after dental surgery: a comparison of small doses of propofol, droperidol, and metoclopramide.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:10

    Topics: Adolescent; Adult; Antiemetics; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Propofol; Tooth Diseases

2003
Effect of metoclopramide on pain on injection of propofol.
    Anaesthesia and intensive care, 2004, Volume: 32, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Anesthesia, General; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Middle Aged; Pain; Pain Measurement; Probability; Propofol; Reference Values; Treatment Outcome

2004
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; Metoclopramide; Midazolam; Middle Aged; Molecular Weight; Pain; Premedication; Propofol; Prospective Studies; Triglycerides

2004
Less postoperative nausea and vomiting after propofol + remifentanil versus propofol + fentanyl anaesthesia during plastic surgery.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Androstanols; Anesthetics, Combined; Anesthetics, Intravenous; Antiemetics; Double-Blind Method; Female; Fentanyl; Humans; Male; Metoclopramide; Middle Aged; Morphine; Neuromuscular Nondepolarizing Agents; Piperidines; Plastic Surgery Procedures; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Remifentanil; Rocuronium

2005
A lidocaine/metoclopramide combination decreases pain on injection of propofol.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:5

    Topics: Adult; Anesthetics, Intravenous; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Propofol

2005
Age-related differences in metoclopramide requirement for pain on injection of propofol.
    Clinical drug investigation, 2006, Volume: 26, Issue:11

    Topics: Adult; Aged; Aging; Double-Blind Method; Female; Humans; Injections; Male; Metoclopramide; Middle Aged; Pain; Propofol

2006
Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients.
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Japan; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Propofol

2007
Metoclopramide does not influence the frequency of propofol-induced spontaneous movements.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:7

    Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Antiemetics; Double-Blind Method; Drug Interactions; Female; Fentanyl; Hiccup; Humans; Hypnotics and Sedatives; Male; Metoclopramide; Midazolam; Middle Aged; Myoclonus; Propofol; Sample Size

2007
Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Flurbiprofen; Humans; Injections, Intravenous; Japan; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Pain Measurement; Propofol; Prospective Studies; Surgical Procedures, Operative; Treatment Outcome; Young Adult

2008
Comparison of propofol, droperidol, and metoclopramide for prophylaxis of postoperative nausea and vomiting after breast cancer surgery: a prospective, randomized, double-blind, placebo-controlled study in Japanese patients.
    Clinical therapeutics, 2008, Volume: 30, Issue:11

    Topics: Aged; Antiemetics; Asian People; Breast Neoplasms; Double-Blind Method; Droperidol; Female; Humans; Injections, Intravenous; Japan; Mastectomy, Modified Radical; Mastectomy, Segmental; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Prevalence; Propofol; Prospective Studies; Treatment Outcome; Wakefulness

2008
Comparison of the efficacy of propofol and metoclopramide in preventing postoperative nausea and vomiting after middle ear surgery.
    Saudi medical journal, 2009, Volume: 30, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Antiemetics; Double-Blind Method; Ear, Middle; Female; Humans; Male; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Propofol

2009
A prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection.
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Adult; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Double-Blind Method; Female; Humans; Ketamine; Lidocaine; Male; Metoclopramide; Pain; Pain Measurement; Propofol; Prospective Studies

2013
The effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:5

    Topics: Adult; Aged; Analgesics; Double-Blind Method; Female; Humans; Injections, Intravenous; Ketamine; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Piperidines; Propofol; Prospective Studies; Remifentanil

2012
Sub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section - a randomized control trial.
    BMC anesthesiology, 2019, 09-14, Volume: 19, Issue:1

    Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections, Spinal; Metoclopramide; Morphine; Postoperative Nausea and Vomiting; Pregnancy; Propofol; Prospective Studies; Pruritus; Quality of Life

2019

Other Studies

10 other study(ies) available for propofol and metoclopramide

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Does propofol interact with D2 dopamine receptors?
    Anesthesia and analgesia, 1994, Volume: 79, Issue:6

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Kinetics; Metoclopramide; Propofol; Receptors, Dopamine D2; Spiperone; Tritium

1994
[Effects of metoclopramide on the hypnotic dosages of propofol].
    Revista espanola de anestesiologia y reanimacion, 1996, Volume: 43, Issue:8

    Topics: Aged; Anesthesia, Local; Antiemetics; Dopamine Antagonists; Drug Synergism; Humans; Hypnotics and Sedatives; Metoclopramide; Middle Aged; Preanesthetic Medication; Propofol; Retinal Detachment

1996
[Propofol anesthesia for ambulatory surgery in adults].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:10

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Local; Fentanyl; Flurbiprofen; Humans; Intraoperative Care; Metoclopramide; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol

2000
Intra-arterial injection of metoclopramide, midazolam, propofol and pethidine.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:3

    Topics: Abdominal Wall; Adolescent; Anesthesia, General; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Follow-Up Studies; Foreign Bodies; Humans; Injections, Intra-Arterial; Insulin; Meperidine; Metoclopramide; Midazolam; Needles; Propofol; Risk Assessment; Treatment Outcome

2002
Anesthesia and Brugada syndrome: a 12-year case series.
    Journal of clinical anesthesia, 2017, Volume: 36

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Anesthetics; Anesthetics, Intravenous; Brugada Syndrome; Child; Child, Preschool; Contraindications; Female; Hemodynamics; Humans; Male; Metoclopramide; Middle Aged; Propofol; Retrospective Studies; Tramadol; Young Adult

2017