Page last updated: 2024-08-16

propofol and lactic acid

propofol has been researched along with lactic acid in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.86)18.7374
1990's3 (8.57)18.2507
2000's14 (40.00)29.6817
2010's16 (45.71)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Donaghey, SF; Laycock, GJ; Logan, RW; Mitchell, IM; Morton, NS; Paton, RD1
Henze, T; Seyde, WC; Sonntag, H; Stephan, H; Textor, J1
Cavallini, L; Dam, M; Ermani, M; Freo, U; Ori, C; Pizzolato, G; Ruggero, S1
Alston, RP; Andrews, PJ; Souter, MJ1
Fujita, N; Goto, F; Kadoi, Y; Okano, N; Saito, S1
Arai, T; Fukuda, K; Inubushi, T; Ishii, H; Morikawa, S; Segawa, H1
Church, T; Egan, TD; Johnson, KB; Kern, SE; McJames, SW; Syroid, N; Whiddon, D; White, JL1
Kill, C; Leonhardt, A; Wulf, H1
Acco, A; Bracht, A; Comar, JF1
Guérit, JM; Hantson, P; Liolios, A; Raftopoulos, C; Scholtes, JL1
Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S1
Chukwuemeka, A; Ko, R; Ralph-Edwards, A1
Fujita, Y; Katsuya, H; Sasano, H; Sasano, N; So, M; Sobue, K1
He, W; Liu, KX; Rinne, T; Wang, F; Xia, Z1
Ahonen, H; Berg, L; Laranne, J; Lindgren, L; Nunes, S; Parviainen, I; Raittinen, LP; Ruokonen, E; Tenhunen, J1
Boileau, P; Carles, M; Dellamonica, J; Lena, D; Levraut, J; Pittet, JF; Raucoules-Aime, M; Roux, J1
Cekic, B; Coskun, I; Eroglu, A; Erturk, E; Geze, S; Karahan, C; Kerimoglu, S; Kosucu, M; Mentese, A; Ulusoy, H1
Lam, AM; Lee, LA; Rozet, I; Tontisirin, N; Treggiari, MM; Vavilala, MS1
Daijo, H; Fukuda, K; Hirota, K; Nishi, K; Oda, S; Takabuchi, S; Tanaka, T; Wakamatsu, T1
Fournell, A; Picker, O; Scheeren, TW; Schober, P; Schwarte, LA; Schwartges, I1
Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL1
Benveniste, H; Glass, PS; Lee, H; Makaryus, R; Rebecchi, M; Smith, SD; Yu, M; Zhang, S1
Cavalcante, SL; Dumaresq, DM; Garcia, JH; Guimarães, SB; Vasconcelos, AR; Vasconcelos, RC1
Kawamura, G; Kitamura, T; Sato, K; Yamada, Y1
Bleichner, JP; Laviolle, B; Malledant, Y; Morandi, X; Seguin, P; Tanguy, M1
Oertel, MF; Preuss, M; Scharbrodt, W; Schomacher, J; Stein, M1
Graffagnino, C; James, ML; Olson, DM1
Fragopoulou, E; Kakisis, J; Kalimeris, K; Kostopanagiotou, G; Kouni, S; Matsota, P; Nomikos, T; Pandazi, A; Vasdekis, S1
Almeida, DC; Barletta, M; Graham, LF; Mathews, LA; Quandt, JE1
Imura, H; Nitta, T; Shirakawa, M1
Bohaychuk-Preuss, KS; Carrozzo, MV; Duke-Novakovski, T1
Carletti, B; Domínguez, JM; Funes, F; Galán, A; Gómez, R; Granados, MM; Martín, EM; Quirós, S; Seisdedos, A1
Ikeda, K; Osuru, HP; Paila, U; Thiele, RH; Zuo, Z1
Dai, Z; Gao, W; Li, G; Li, Y; Lin, M; Wang, G; Wang, J; Zhu, Y1

Trials

10 trial(s) available for propofol and lactic acid

ArticleYear
EEG burst suppression with propofol during cardiopulmonary bypass in children: a study of the haemodynamic, metabolic and endocrine effects.
    British journal of anaesthesia, 1992, Volume: 69, Issue:4

    Topics: Adolescent; Blood Glucose; Blood Pressure; Cardiopulmonary Bypass; Child; Child, Preschool; Electroencephalography; Female; Humans; Hydrocortisone; Infant; Lactates; Lactic Acid; Male; Oxygen Consumption; Propofol; Triiodothyronine

1992
Propofol does not ameliorate cerebral venous oxyhemoglobin desaturation during hypothermic cardiopulmonary bypass.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:5

    Topics: Aged; Anaerobiosis; Anesthetics, Intravenous; Cardiopulmonary Bypass; Cerebrovascular Circulation; Female; Humans; Hypothermia, Induced; Lactic Acid; Male; Middle Aged; Oxyhemoglobins; Propofol; Prospective Studies

1998
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia-reperfusion.
    British journal of anaesthesia, 2008, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Glucose; Glycerol; Glycolysis; Humans; Ischemic Preconditioning; Knee Joint; Lactic Acid; Male; Methyl Ethers; Microdialysis; Middle Aged; Muscle, Skeletal; Propofol; Pyruvic Acid; Reperfusion Injury; Sevoflurane; Tourniquets

2008
Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Blood Gas Analysis; Double-Blind Method; Female; Humans; Lactic Acid; Male; Malondialdehyde; Middle Aged; Propofol; Prospective Studies; Reperfusion Injury; Tourniquets; Treatment Outcome; Young Adult

2009
Metabolic and oxidative effects of sevoflurane and propofol in children undergoing surgery for congenital heart disease.
    Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1

    Topics: Adolescent; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Female; Glutathione; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Lactic Acid; Male; Methyl Ethers; Oxidative Stress; Propofol; Prospective Studies; Pyruvic Acid; Sevoflurane; Thiobarbituric Acid Reactive Substances; Time Factors

2011
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury.
    Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6

    Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hypnotics and Sedatives; Lactic Acid; Male; Microdialysis; Midazolam; Neuroprotective Agents; Propofol; Pyruvic Acid; Single-Blind Method

2012
A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:6

    Topics: Body Temperature; Brain Injuries; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intracranial Pressure; Lactic Acid; Microdialysis; Oximetry; Pilot Projects; Propofol; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Trauma Severity Indices

2012
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Endarterectomy, Carotid; Female; Humans; Ischemia; Lactic Acid; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Methyl Ethers; Middle Aged; Monitoring, Intraoperative; Neuropsychological Tests; Nitrates; Nitrites; Oxidative Stress; P-Selectin; Propofol; S100 Proteins; Sevoflurane

2013
Evaluation of serial venous and arterial lactate concentrations in healthy anesthetized sheep undergoing ovariectomy.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:5

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Blood Chemical Analysis; Female; Infusions, Intravenous; Lactic Acid; Ovariectomy; Propofol; Prospective Studies; Sheep

2014
Phrenic nerve block during nonintubated video-assisted thoracoscopic surgery: a single-centre, double-blind, randomized controlled trial.
    Scientific reports, 2021, 06-22, Volume: 11, Issue:1

    Topics: Blood Pressure; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Middle Aged; Nerve Block; Phrenic Nerve; Postoperative Complications; Propofol; Systole; Thoracic Surgery, Video-Assisted; Treatment Outcome

2021

Other Studies

25 other study(ies) available for propofol and lactic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Energy and amino acid metabolism in the human brain under Disoprivan anesthesia with various paCO2 values].
    Der Anaesthesist, 1988, Volume: 37, Issue:5

    Topics: Amino Acids; Anesthesia, General; Anesthetics; Blood Glucose; Brain; Carbon Dioxide; Cerebrovascular Circulation; Coronary Artery Bypass; Coronary Disease; Energy Metabolism; Humans; Lactates; Lactic Acid; Male; Middle Aged; Neurotransmitter Agents; Oxygen; Phenols; Propofol

1988
The effects of propofol on cerebral high energy metabolites, lactate, and glucose in normoxic and severely hypoxic rats.
    Life sciences, 1997, Volume: 60, Issue:16

    Topics: Adenine Nucleotides; Anesthetics, Intravenous; Animals; Cerebral Cortex; Energy Metabolism; Glucose; Hypoxia; Lactic Acid; Male; Oxygen; Phosphocreatine; Propofol; Pyruvic Acid; Rats; Rats, Inbred F344

1997
Disturbances in hepatocellular function during cardiopulmonary bypass using propofol anaesthesia.
    European journal of anaesthesiology, 2001, Volume: 18, Issue:12

    Topics: Alanine Transaminase; Anesthetics, Intravenous; Bilirubin; Cardiopulmonary Bypass; Coronary Artery Bypass; Hepatic Artery; Hepatic Veins; Humans; Hyaluronic Acid; Ketone Bodies; Lactic Acid; Liver; Middle Aged; Monitoring, Intraoperative; Oxygen; Propofol

2001
Effects of propofol on lactate accumulation and oedema formation in focal cerebral ischaemia in hyperglycaemic rats.
    British journal of anaesthesia, 2002, Volume: 88, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Brain; Brain Edema; Brain Ischemia; Hyperglycemia; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Propofol; Rats; Rats, Inbred SHR

2002
The influence of hemorrhagic shock on propofol: a pharmacokinetic and pharmacodynamic analysis.
    Anesthesiology, 2003, Volume: 99, Issue:2

    Topics: Algorithms; Analysis of Variance; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Glucose; Blood Pressure; Computer Simulation; Female; Heart Rate; Isoflurane; Lactic Acid; Male; Nonlinear Dynamics; Pilot Projects; Propofol; Shock, Hemorrhagic; Swine

2003
Lacticacidosis after short-term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:9

    Topics: Acidosis, Lactic; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Dose-Response Relationship, Drug; Fasting; Femoral Fractures; Fentanyl; Hemodynamics; Humans; Lactic Acid; Male; Neuromuscular Nondepolarizing Agents; Osteogenesis Imperfecta; Propofol; Succinylcholine; Time Factors

2003
Metabolic effects of propofol in the isolated perfused rat liver.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:4

    Topics: Alanine; Anesthetics, Intravenous; Animals; Energy Metabolism; Gluconeogenesis; Glycerol; Glycolysis; In Vitro Techniques; Infusions, Intravenous; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxygen; Phosphorylation; Propofol; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2004
Propofol infusion syndrome associated with short-term large-dose infusion during surgical anesthesia in an adult.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Acidosis, Lactic; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Stem Neoplasms; Electrocardiography; Electrolytes; Hemangioma; Humans; Infusions, Intravenous; Intraoperative Complications; Lactic Acid; Male; Propofol

2005
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    Anesthesiology, 2006, Volume: 104, Issue:1

    Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Creatine Kinase; Cresols; Dose-Response Relationship, Drug; Electrolytes; Glucose; Halothane; Ketamine; Lactic Acid; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Propofol; Pyruvic Acid; Ryanodine Receptor Calcium Release Channel; Swine

2006
Short-term low-dose propofol anaesthesia associated with severe metabolic acidosis.
    Anaesthesia and intensive care, 2006, Volume: 34, Issue:5

    Topics: Acidosis; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Bicarbonates; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Resuscitation; Coronary Angiography; Coronary Artery Bypass; Heart Rate; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Intensive Care Units; Lactic Acid; Male; Propofol

2006
Anesthetic management of a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) during laparotomy.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Amides; Anesthesia; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Blood Gas Analysis; Body Temperature; Diabetes Mellitus, Type 1; Fentanyl; Gastrectomy; Humans; Intubation, Intratracheal; Isotonic Solutions; Lactic Acid; Lidocaine; Male; MELAS Syndrome; Middle Aged; Neuromuscular Nondepolarizing Agents; Propofol; Ropivacaine; Stomach Neoplasms; Time Factors; Vecuronium Bromide

2007
Propofol attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rat.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:5

    Topics: Animals; Endothelin-1; Free Radical Scavengers; Intestinal Mucosa; Intestine, Small; Lactic Acid; Male; Malondialdehyde; Nitric Oxide; Propofol; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Superoxide Dismutase

2007
Deep sedation with dexmedetomidine in a porcine model does not compromise the viability of free microvascular flap as depicted by microdialysis and tissue oxygen tension.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cell Survival; Central Venous Pressure; Consciousness; Dexmedetomidine; Female; Glucose; Hypnotics and Sedatives; Lactic Acid; Microcirculation; Microdialysis; Models, Animal; Oxygen; Partial Pressure; Propofol; Pyruvic Acid; Rectus Abdominis; Surgical Flaps; Sus scrofa; Sympathectomy; Time Factors; Vascular Resistance

2007
Prolonged propofol anesthesia is not associated with an increase in blood lactate.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:4

    Topics: Acidosis, Lactic; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Drug Administration Schedule; Female; Humans; Hydrogen-Ion Concentration; Isoflurane; Lactic Acid; Male; Methyl Ethers; Middle Aged; Propofol; Retrospective Studies; Sevoflurane; Spine

2009
The intravenous anesthetic propofol inhibits lipopolysaccharide-induced hypoxia-inducible factor 1 activation and suppresses the glucose metabolism in macrophages.
    Journal of anesthesia, 2010, Volume: 24, Issue:1

    Topics: Adenosine Triphosphate; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Lipopolysaccharides; Macrophages; Propofol; Protein Biosynthesis; RNA, Messenger

2010
Sevoflurane and propofol anaesthesia differentially modulate the effects of epinephrine and norepinephrine on microcirculatory gastric mucosal oxygenation.
    British journal of anaesthesia, 2010, Volume: 105, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Female; Gastric Mucosa; Hemodynamics; Lactic Acid; Male; Methyl Ethers; Microcirculation; Norepinephrine; Oxygen Consumption; Propofol; Respiration, Artificial; Sevoflurane; Vasoconstrictor Agents

2010
Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage.
    Neurocritical care, 2011, Volume: 15, Issue:1

    Topics: Adult; Biomarkers; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lactic Acid; Propofol; Pyruvic Acid; Subarachnoid Hemorrhage; Syndrome

2011
The metabolomic profile during isoflurane anesthesia differs from propofol anesthesia in the live rodent brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Isoflurane; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolome; Propofol; Rats; Rats, Inbred F344

2011
The involvement of adenosine triphosphate-sensitive potassium channels in the different effects of sevoflurane and propofol on glucose metabolism in fed rats.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Heart Rate; Hypovolemia; Insulin; Insulin-Secreting Cells; KATP Channels; Lactic Acid; Male; Methyl Ethers; Postprandial Period; Potassium Channel Blockers; Propofol; Rats; Rats, Sprague-Dawley; Sevoflurane; Time Factors

2012
Cerebrospinal fluid lactate concentration after withdrawal of metabolic suppressive therapy in subarachnoid hemorrhage.
    Acta neurochirurgica. Supplement, 2012, Volume: 114

    Topics: Adult; Aged; Female; Fentanyl; Glasgow Outcome Scale; Humans; Hypnotics and Sedatives; Intensive Care Units; Lactic Acid; Male; Midazolam; Middle Aged; Observation; Propofol; Prospective Studies; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome

2012
Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Cyclosporine; Heart; Hemodynamics; Lactic Acid; Myocardium; Propofol; Protective Agents; Rabbits; Reperfusion Injury

2014
Cardiopulmonary effects of pleural insufflation with CO
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:3

    Topics: Anesthesia; Anesthetics; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Female; Heart Rate; Horses; Insufflation; Isoflurane; Ketamine; Lactic Acid; Male; Patient Positioning; Pleura; Positive-Pressure Respiration; Propofol; Prospective Studies; Respiration, Artificial; Respiratory Dead Space; Stroke Volume; Xylazine

2017
Anesthetic effects of isoflurane and propofol on cerebrospinal fluid biochemical markers in healthy dogs.
    Veterinary clinical pathology, 2019, Volume: 48, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Biomarkers; Dogs; Energy Metabolism; Female; Isoflurane; Lactic Acid; Male; Propofol; Prospective Studies

2019
Impact of inflammation on brain subcellular energetics in anesthetized rats.
    BMC neuroscience, 2019, 07-15, Volume: 20, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain; Electron Transport Complex IV; Heme Oxygenase (Decyclizing); HSP90 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Isoflurane; Lactic Acid; Male; NF-kappa B; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Propofol; Protein Carbonylation; Rats; Typhlitis

2019