propofol has been researched along with flumazenil in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.33) | 18.7374 |
| 1990's | 20 (33.33) | 18.2507 |
| 2000's | 14 (23.33) | 29.6817 |
| 2010's | 16 (26.67) | 24.3611 |
| 2020's | 8 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chollet-Rivier, M; Ravussin, P | 1 |
| Ilkiw, JE | 1 |
| Mori, K; Murayama, T; Ogawa, T; Shindo, K; Shingu, K; Tamai, S; Tomoda, K | 1 |
| Hales, TG; Lambert, JJ | 1 |
| Spiess, BD | 1 |
| Dundas, CR; Norton, AC | 1 |
| Harvey, PB; Kestin, IG; Nixon, C | 1 |
| Freys, G; Jochum, D; Otteni, JC; Ravanello, J; Schaal, JC; Steib, A | 1 |
| Beller, JP; Curzola, U; Freys, G; Jochum, D; Otteni, JC; Ravanello, J; Steib, A | 1 |
| Forrest, P; Galletly, DC | 1 |
| Chao, CC; Fan, SZ; Lin, SM; Liu, CC; Yu, HY | 1 |
| D'Honneur, G; Duvaldestin, P; el Sayed, A; Lambert, Y; Rimaniol, JM | 1 |
| Ghouri, AF; Ruiz, MA; White, PF | 1 |
| Favre, JB; Moeschler, O; Ravussin, P | 1 |
| Hara, M; Ikemoto, Y; Kai, Y | 1 |
| Fassoulaki, A; Papilas, K; Sarantopoulos, C | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Rodrigo, MR | 1 |
| Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL | 1 |
| Murata, Y | 1 |
| Larson, JS; Lunn, JJ | 1 |
| Kamei, J; Ohsawa, M | 1 |
| Adachi, Y; Higuchi, H; Satoh, T; Uchihashi, Y; Watanabe, K | 1 |
| Adachi, YU; Higuchi, H; Satoh, T; Watanabe, K | 2 |
| Bluhm, B; Mendelson, WB; Tung, A | 1 |
| Masuzawa, M; Miyamoto, E; Murayama, T; Nagata, A; Nakao, S; Shingu, K | 1 |
| Bragulat, E; Coll-Vinent, B; Espinosa, G; Fernández, C; Millá, J; Miró, O; Sala, X; Sánchez, M | 1 |
| Aalto, S; Hietala, J; Hinkka, S; Kaisti, KK; Korpi, ER; Metsähonkala, L; Någren, K; Oikonen, V; Salmi, E; Scheinin, H | 1 |
| Cappell, MS | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Adachi, Y; Doi, M; Obata, Y; Sato, S; Suzuki, K | 1 |
| Gerónimo Pardo, M; Mateo Cerdán, CM; Moreno Salcedo, JM | 1 |
| Kanmura, Y; Moriyama, T; Tsuneyoshi, I | 1 |
| Oppitz, F | 1 |
| Baker, B; Raphael, D; Rinehart, JB | 1 |
| Ichinohe, T; Matsuura, N; Tomita, S | 1 |
| Kawamata, M; Kawamata, T; Koike, Y; Yamamoto, K | 1 |
| Diedrich, A; Dietrich, CG; Drouven, FM; Kottmann, T | 1 |
| Dong, Y; Shao, H; Xia, W; Xie, Z; Yu, B; Zhang, Y | 1 |
| Absalom, NL; Chebib, M; Chua, HC; Hanrahan, JR; Viswas, R | 1 |
| Absalom, NL; Chebib, M; Christensen, ET; Chua, HC; Hartiadi, LY; Hoestgaard-Jensen, K; Jensen, AA; Ramzan, I | 1 |
| Vicari, JJ | 1 |
| Baik, HJ; Moon, S | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
| Adachi, YU; Higashi, M; Matsuda, N; Okuda, M; Sato, AB; Satomoto, M; Taharabaru, S; Tamura, T | 1 |
| Doi, M; Katoh, T; Kobayashi, M; Kurita, T; Mimuro, S; Nakajima, Y; Sato, T | 1 |
| Cho, HY; Kim, WH; Kim, YJ; Lee, HB; Lee, HJ; Seo, JH | 1 |
| Huang, J; Liu, M; Luo, W; Miao, C; Sun, M; Wan, J; Xia, L; Xiong, W; Xu, P; Zhang, J; Zhang, X; Zhang, Z; Zhong, J | 1 |
| Shimizu, T; Takasusuki, T; Yamaguchi, S | 1 |
| Choi, EA; Chung, YJ; Kwon, EJ; Lee, JH; Min, JJ; Oh, EJ; On, YK | 1 |
| Haraki, T; Horikawa, YT; Kamiya, S; Kido, K; Kondo, T; Nakamura, R; Narasaki, S; Oshita, K; Saeki, N; Toyota, Y; Tsutsumi, YM | 1 |
5 review(s) available for propofol and flumazenil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Other potentially useful new injectable anesthetic agents.
Topics: Anesthesia; Anesthetics; Animals; Cats; Dogs; Flumazenil; Midazolam; Propofol | 1992 |
Comparing drugs for short-term sedation.
Topics: Anesthesia; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Lorazepam; Midazolam; Pain; Propofol | 1994 |
Sedation and analgesia for gastrointestinal endoscopy during pregnancy.
Topics: Analgesia; Analgesics, Opioid; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Female; Fentanyl; Fetus; Flumazenil; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Meperidine; Naloxone; Pregnancy; Propofol; Risk Assessment; Triage | 2006 |
Sedation in the Ambulatory Endoscopy Center: Optimizing Safety, Expectations and Throughput.
Topics: Ambulatory Care Facilities; Analgesics, Opioid; Antidotes; Benzodiazepines; Conscious Sedation; Deep Sedation; Efficiency; Endoscopy, Gastrointestinal; Flumazenil; Humans; Hypnotics and Sedatives; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Patient Safety; Propofol | 2016 |
18 trial(s) available for propofol and flumazenil
| Article | Year |
|---|---|
Midazolam-flumazenil vs. propofol in ambulatory ENT endoscopic procedures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia Recovery Period; Anesthesia, Intravenous; Awareness; Blood Pressure; Cardiovascular Diseases; Endoscopy; Flumazenil; Heart Rate; Humans; Midazolam; Middle Aged; Otorhinolaryngologic Diseases; Propofol; Risk Factors; Safety; Time Factors | 1992 |
Induction agents for day-case anaesthesia. A double-blind comparison of propofol and midazolam antagonised by flumazenil.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Propofol; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Psychomotor recovery after three methods of sedation during spinal anaesthesia.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Spinal; Double-Blind Method; Flicker Fusion; Flumazenil; Humans; Male; Memory, Short-Term; Midazolam; Preanesthetic Medication; Propofol; Prostatectomy; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Recovery from total intravenous anaesthesia. Propofol versus midazolam-flumazenil.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Arousal; Blood Pressure; Eyelashes; Flumazenil; Humans; Memory; Midazolam; Middle Aged; Motor Skills; Propofol; Reflex; Time Factors | 1990 |
Comparison of propofol and antagonised midazolam anaesthesia for day-case surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Intravenous; Anesthetics; Arousal; Clinical Trials as Topic; Cystoscopy; Double-Blind Method; Female; Flumazenil; Humans; Isoflurane; Male; Midazolam; Middle Aged; Nitrous Oxide; Phenols; Propofol; Psychomotor Performance; Random Allocation | 1987 |
Lack of effect of flumazenil on the reversal of propofol anaesthesia.
Topics: Adult; Anesthesia; Double-Blind Method; Drug Interactions; Female; Flumazenil; Humans; Propofol | 1995 |
Midazolam/propofol but not propofol alone reversibly depress the swallowing reflex.
Topics: Ambulatory Care; Anesthesia, Intravenous; Awareness; Colonoscopy; Deglutition; Depression, Chemical; Double-Blind Method; Drug Combinations; Electromyography; Flumazenil; Humans; Hyoid Bone; Midazolam; Placebos; Propofol; Reaction Time; Reflex | 1994 |
Effect of flumazenil on recovery after midazolam and propofol sedation.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Cognition; Conscious Sedation; Female; Flumazenil; Humans; Midazolam; Middle Aged; Monitoring, Intraoperative; Propofol; Psychomotor Performance | 1994 |
Flumazenil reduces the duration of thiopentone but not of propofol anaesthesia in humans.
Topics: Anesthesia, Intravenous; Dilatation and Curettage; Double-Blind Method; Female; Flumazenil; Humans; Middle Aged; Movement; Placebos; Propofol; Thiopental; Time Factors | 1993 |
Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidotes; Arousal; Child; Drug Costs; Evoked Potentials, Somatosensory; Female; Flumazenil; Humans; Intraoperative Care; Intubation, Intratracheal; Male; Memory; Midazolam; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Pain; Postoperative Care; Propofol; Prospective Studies; Psychomotor Performance; Scoliosis; Spinal Cord; Wakefulness | 1998 |
A small dose of midazolam decreases the time to achieve hypnosis without delaying emergence during short-term propofol anesthesia.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flumazenil; GABA Modulators; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Propofol; Prospective Studies | 2001 |
Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Clinical Protocols; Conscious Sedation; Drug Therapy, Combination; Electric Countershock; Emergency Medical Services; Etomidate; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myoclonus; Outcome and Process Assessment, Health Care; Propofol; Prospective Studies; Treatment Outcome | 2003 |
The combined effects of midazolam and propofol sedation on muscle power.
Topics: Adult; Bite Force; Conscious Sedation; Consciousness Monitors; Cross-Over Studies; Flumazenil; Hand Strength; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazolam; Muscle Strength; Muscle Strength Dynamometer; Muscle, Skeletal; Neuropsychological Tests; Propofol; Sample Size; Stroop Test | 2013 |
Comparison of the recovery profile of remimazolam with flumazenil and propofol anesthesia for open thyroidectomy.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Flumazenil; Humans; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Thyroidectomy | 2023 |
Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Flumazenil; Humans; Hypotension; Pain; Propofol; Prospective Studies | 2023 |
Remimazolam Compared to Propofol for Total Intravenous Anesthesia with Remifentanil on the Recovery of Psychomotor Function: A Randomized Controlled Trial.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Flumazenil; Humans; Piperidines; Propofol; Remifentanil | 2023 |
Comparison of propofol vs. remimazolam on emergence profiles after general anesthesia: A randomized clinical trial.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Benzodiazepines; Flumazenil; Humans; Propofol; Prospective Studies | 2023 |
Remimazolam-based anesthesia with flumazenil allows faster emergence than propofol-based anesthesia in older patients undergoing spinal surgery: A randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Benzodiazepines; Flumazenil; Humans; Propofol; Prospective Studies; Single-Blind Method | 2023 |
37 other study(ies) available for propofol and flumazenil
| Article | Year |
|---|---|
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Flumazenil does not antagonize halothane, thiamylal or propofol anaesthesia in rats.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Behavior, Animal; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Halothane; Male; Propofol; Rats; Rats, Inbred Strains; Sleep; Thiamylal | 1992 |
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Cerebral Cortex; Chromaffin System; Electric Stimulation; Female; Flumazenil; GABA-A Receptor Antagonists; Ion Channel Gating; Mice; Neural Conduction; Neurons; Pentobarbital; Pregnancy; Propofol; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glycine; Receptors, Neurotransmitter | 1991 |
Two new pharmacological agents for the 1990s: flumazenil and propofol.
Topics: Adjuvants, Anesthesia; Flumazenil; Humans; Perioperative Nursing; Propofol; Recovery Room | 1990 |
[Comparative study of resuscitation from intravenous anesthesia with the exclusive use of propofol or midazolam and flumazenil].
Topics: Adult; Anesthesia, Intravenous; Drug Combinations; Flumazenil; Humans; Male; Midazolam; Postoperative Period; Propofol | 1989 |
[Indications for total intravenous anesthesia (TIVA) in neuroanesthesia].
Topics: Anesthesia, Intravenous; Brain; Flumazenil; Humans; Isoflurane; Nitric Oxide; Propofol | 1993 |
Propofol activates GABAA receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat.
Topics: Animals; Central Nervous System; Chloride Channels; Chlorides; Diazepam; Flumazenil; Hippocampus; Kinetics; Membrane Potentials; Neurons; Propofol; Pyramidal Tracts; Rats; Rats, Wistar; Receptors, GABA | 1993 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Use of inhalational and intravenous sedation in dentistry.
Topics: Accidents; Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Anxiety Agents; Antidotes; Cause of Death; Computers; Conscious Sedation; Dental Care; Diazepam; Drug Overdose; Emergencies; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Infusion Pumps; Isoflurane; Midazolam; Nitrous Oxide; Oxygen; Practice Guidelines as Topic; Propofol; United Kingdom | 1997 |
[Effects of anesthetics on somatosensory evoked potentials by median nerve stimulation in human--analyses after single administration in volunteers].
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation; Evoked Potentials, Somatosensory; Flumazenil; Humans; Male; Median Nerve; Midazolam; Naloxone; Nitrous Oxide; Propofol; Reaction Time; Thiopental | 1998 |
Modification of the effect of diazepam on the propofol-induced loss of the righting reflex in mice by diabetes.
Topics: Anesthetics, Intravenous; Animals; Diabetes Mellitus, Experimental; Diazepam; Flumazenil; GABA Modulators; Injections, Intravenous; Male; Mice; Mice, Inbred ICR; Posture; Propofol; Receptors, GABA-A; Reflex | 1999 |
[Preliminary report: the effect of flumazenil on the hypnotic dose of propofol in ddY mice].
Topics: Acetic Acid; Anesthetics, Intravenous; Animals; Buffers; Drug Synergism; Flumazenil; GABA-A Receptor Antagonists; Hydrogen-Ion Concentration; Hypnosis, Anesthetic; Male; Mice; Propofol | 2001 |
Sleep inducing effects of propofol microinjection into the medial preoptic area are blocked by flumazenil.
Topics: Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; GABA Modulators; Male; Neurons; Preoptic Area; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Sleep, REM | 2001 |
High-dose flumazenil potentiates the hypnotic activity of propofol, but not that of thiopental, in ddY mice.
Topics: Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Synergism; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Male; Mice; Midazolam; Propofol; Thiopental | 2001 |
Inhibitory effect of propofol on ketamine-induced c-Fos expression in the rat posterior cingulate and retrosplenial cortices is mediated by GABAA receptor activation.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Bicuculline; Cerebral Cortex; Electroencephalography; Excitatory Amino Acid Antagonists; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Gene Expression Regulation; Genes, fos; Gyrus Cinguli; Hemodynamics; Image Processing, Computer-Assisted; Immunohistochemistry; Ketamine; Male; Propofol; Rats; Rats, Wistar | 2003 |
Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Gas Analysis; Brain; Carbon Dioxide; Electrocardiography; Electroencephalography; Flumazenil; GABA Modulators; Hemodynamics; Humans; Male; Methyl Ethers; Models, Biological; Oxygen; Positron-Emission Tomography; Propofol; Receptors, GABA-A; Reflex; Sevoflurane; Tissue Distribution | 2004 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
[Patient awakening from anesthesia was re-sedated by administration of flumazenil].
Topics: Aged, 80 and over; Anesthesia Recovery Period; Drug Synergism; Female; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2008 |
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatography, Endoscopic Retrograde; Choledocholithiasis; Decerebrate State; Flumazenil; GABA Agonists; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Intubation, Intratracheal; Male; Midazolam; Middle Aged; Naloxone; Piperidines; Propofol; Remifentanil; Sleep Apnea, Obstructive | 2010 |
Effects of a novel benzodiazepine derivative, JM-1232(-), on human gastroepiploic artery in vitro.
Topics: Dose-Response Relationship, Drug; Endothelium, Vascular; Flumazenil; GABA Modulators; Gastroepiploic Artery; Humans; In Vitro Techniques; Isoindoles; Midazolam; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotic Antagonists; Norepinephrine; Piperazines; Potassium; Propofol; Structure-Activity Relationship; Vasoconstrictor Agents | 2011 |
[Case report: a 65-year-old man loses consciousness after colonoscopy].
Topics: Aged; Ambulatory Care; Anesthetics, Intravenous; Atropine; Bradycardia; Cholinergic Antagonists; Colonoscopy; Conscious Sedation; Diagnosis, Differential; Emergency Medical Services; Flumazenil; GABA Modulators; Hospitals, Rural; Humans; Hypnotics and Sedatives; Male; Midazolam; Muscarinic Antagonists; Propofol; Telephone; Unconsciousness | 2010 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desflurane; Diabetes Mellitus, Type 2; Fentanyl; Flumazenil; GABA Modulators; Humans; Hydromorphone; Isoflurane; Male; Midazolam; Middle Aged; Pancreatitis; Postoperative Complications; Propofol | 2012 |
[Improvement of consciousness by administration of flumazenil in a patient with unexpectedly delayed emergence from general anesthesia].
Topics: Anesthesia Recovery Period; Anesthesia, General; Consciousness; Female; Flumazenil; Humans; Middle Aged; Piperidines; Propofol; Remifentanil | 2013 |
Sedation-associated complications in endoscopy are not reduced significantly by implementation of the German S-3-guideline and occur in a severe manner only in patients with ASA class III and higher.
Topics: Antidotes; Apnea; Critical Care; Deep Sedation; Delivery of Health Care; Endoscopy, Gastrointestinal; Flumazenil; Germany; Guidelines as Topic; Health Status; Humans; Hypnotics and Sedatives; Personnel Staffing and Scheduling; Propofol; Retrospective Studies | 2013 |
Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloidogenic Proteins; Animals; Brain; Caspases; Cell Line, Tumor; Cognition; Disease Models, Animal; Flumazenil; GABA Agonists; GABA Antagonists; Humans; Maze Learning; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nootropic Agents; Propofol; Random Allocation | 2014 |
The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries.
Topics: Anesthetics, Intravenous; Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Etomidate; Female; Flavones; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Humans; Propofol; Protein Subunits; Receptors, GABA-A; Xenopus laevis; Zinc Compounds | 2015 |
Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.
Topics: Anesthetics; Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Interactions; Drug Synergism; Etomidate; Flumazenil; Humans; Kava; Mutation; Propofol; Protein Subunits; Pyrones; Receptors, GABA-A; Xenopus laevis | 2016 |
Aminophylline and Ephedrine, but Not Flumazenil, Inhibit the Activity of the Excitatory Amino Acid Transporter 3 Expressed in
Topics: Aminophylline; Animals; Ephedrine; Excitatory Amino Acid Transporter 3; Flumazenil; Gene Expression Regulation, Developmental; Glutamic Acid; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Propofol; Protein Kinase C; Protein Kinase Inhibitors; Xenopus laevis | 2018 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |
JM-1232(-) and propofol, a new combination of hypnotics with short-acting and non-cumulative preferable properties.
Topics: Anesthesia Recovery Period; Animals; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Flumazenil; GABA-A Receptor Agonists; Hypnotics and Sedatives; Infusions, Intravenous; Isoindoles; Male; Mice, Inbred Strains; Piperazines; Propofol | 2021 |
Recall of extubation after remimazolam anesthesia with flumazenil antagonism during emergence: a retrospective clinical study.
Topics: Airway Extubation; Anesthesia, General; Flumazenil; Humans; Propofol; Retrospective Studies | 2022 |