Page last updated: 2024-08-16

propofol and clonidine

propofol has been researched along with clonidine in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (29.41)18.2507
2000's32 (47.06)29.6817
2010's14 (20.59)24.3611
2020's2 (2.94)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jarvis, AP; Prys-Roberts, C; Richards, MJ; Skues, MA1
De Kock, M; Deckers, G; Famenne, F; Scholtes, JL1
Desmonts, JM; Henzel, D; Laudenbach, V; Lecharny, JB; Mantz, J; Peytavin, G1
Devcic, A; Ebert, TJ; Muzi, M1
Kulka, PJ; Sczepanski, U; Tryba, M; Zenz, M1
Bhatti, TH; Khan, RM; Maroof, M1
Peduto, VA; Piga, M; Pisanu, GM1
Bonnet, F; Delaunay, L; Herail, T; Lienhart, A; Sessler, DI1
Tryba, M1
Braccia, G; Demaria, PA; Rodgers, C1
Horn, EP; Schulte am Esch, J; Sessler, DI; Steinfath, M; Werner, C1
Ishizuka, I; Kakoi, H; Kawasaki, J; Kawazoe, T; Kodaka, M; Miyao, H; Okamoto, Y1
Almenza, L; Descraques, C; Grenapin, O; Guglielminotti, J; Mantz, J; Petitmaire, S1
Imai, Y; Kagawa, K; Kirita, T; Kishi, Y; Kita, T; Mammoto, T; Murakami, K; Sakai, T; Sugimura, M1
Berendes, E; Erren, M; Junker, R; Loick, HM; Meissner, A; Möllhoff, T; Rolf, N; Scheld, HH; Schmid, C; Schmidt, C; Van Aken, H1
Buckland, MR; Bujor, MA; Davis, BB; Esmore, DS; Hall, J; Holdgaard, HO; Hunt, JO; McRae, R; Moloney, J; Morgan, DJ; Myles, PS1
De Kock, M; Gautier, P; Jonniaux, M; Lavand'homme, P; Pavlopoulou, A1
Dohi, S; Hayakawa-Fujii, Y; Iida, H1
Goyagi, T; Nishikawa, T; Tanaka, M2
Krause, T; Paris, A; Scholz, J; Steinfath, M; Tonner, PH; von Knobelsdorff, G; Wappler, F1
Ciccone, A; Ciccozzi, A; Cocco, C; Donatelli, F; Facchetti, G; Marinangeli, F; Paladini, A; Pasqualucci, A; Varrassi, G1
Bovill, JG; Ihan, A; Novak-Jankoviĉ, V; Osredkar, J; Paver-E&rcirc;en, V1
Friedberg, BL; Sigl, JC1
Caldwell, JE; Heier, T; Richardson, CA; Talke, PO1
Fujii, Y; Handa, F1
Inoue, T; Ogawa, R; Ogura, A; Wajima, Z; Yoshikawa, T1
Fehr, SB; Pasch, T; Rentsch, KM; Rohling, RG; Seifert, B; Spahn, DR; Zalunardo, MP1
Adachi, Y; Arimura, S; Higuchi, H; Ogata, M; Satoh, T1
Adachi, Y; Arimura, S; Dahan, A; Higuchi, H; Mori, T; Olofsen, E; Satoh, T1
Adachi, Y; Arimura, S; Higuchi, H; Nitahara, K; Satoh, T1
Hirota, K; Ishihara, H; Kubota, T; Kushikata, T; Matsuki, A; Yoshida, H1
Dörges, V; Gerlach, K; Hüppe, M; Kraatz, E; Saager, L; Schmitz, A; Schmucker, P; Uhlig, T1
Ishiyama, T; Kashimoto, S; Kumazawa, T; Matsukawa, T; Oguchi, T1
Dietrich, PJ; Grottke, O; Krause, TH; Müller, J; Wappler, F1
Goktan, C; Mirzai, H; Ok, G; Tarhan, S; Tekin, I1
Dohi, S; Iida, H; Kumazawa, M; Osawa, Y; Sumi, K; Tanahashi, S; Uchida, M1
Altan, A; Turgut, N; Türkmen, A; Ustün, H; Yildiz, F1
Hachenberg, T; Huth, C; Kozian, A; Schilling, T; Tiede, T1
Fischer, M; Franck, M; Martin, J; Parsch, A; Spies, C; Wernecke, KD1
Acheson, M; Morris, J; Myles, PS; Reeves, M1
Kondrat'ev, A; Paleĭ, DA1
Gordeev, VI; Kachalova, EG; Mokhammed Khusseĭn, IaIa; Ul'rikh, GE1
Goyagi, T; Minamizono, T; Nishikawa, T; Tanaka, M1
Fukushima, H; Furuya, A; Ishiyama, T; Kashimoto, S; Kumazawa, T; Oguchi, T1
Fournell, A; Picker, O; Scheeren, TW; Schwarte, LA; Schwartges, I1
Bithal, PK; Chaturvedi, A; Dash, HH; Ghosh, I; Prabhakar, H1
Liatsi, D; Matamis, D; Pampori, S; Pneumatikos, I; Tsagourias, M; Tsapas, B1
Batra, YK; Lokesh, VC; Panda, NB; Rakesh, SV; Subramanyam, R1
Cao, JP; Liu, J; Miao, XY; Shi, XY1
Anitescu, M; Patil, SK1
Chumas, P; Guruswamy, V; Liddington, M; Rothera, E; Russell, J1
Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P1
Bienert, A; Grześkowiak, E; Józefowicz, M; Kokot, ZJ; Kusza, K; Matysiak, J; Pachutko, A; Przybyłowski, K; Wawrzyniak, K; Wiczling, P1
Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC1
Keating, GM1
Anghelescu, DL; Moore, AD1
Ahiskalioglu, A; Alici, HA; Ari, MA; Celik, EC; Dostbil, A; Doymus, O; Karadeniz, E; Oral Ahiskalioglu, E; Sengoz, F; Yayik, AM1
Constable, N; Jones, M; Thomas, C; Walters, M1
Sun, S; Tan, D; Wang, F; Xia, H1
Barbosa, TP; Bastos, AS; Beccaria, LM; Silva, DCD1
Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN1

Reviews

6 review(s) available for propofol and clonidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Clonidine; Desflurane; Dexmedetomidine; Halothane; Humans; Isoflurane; Methyl Ethers; Midazolam; Propofol; Sevoflurane

2014
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
    The Cochrane database of systematic reviews, 2015, Jan-06, Volume: 1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors

2015
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
    Drugs, 2015, Volume: 75, Issue:10

    Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; Hypnotics and Sedatives; Propofol

2015
Emergence Delirium in Pediatric Anesthesia.
    Paediatric drugs, 2017, Volume: 19, Issue:1

    Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence Delirium; Fentanyl; Humans; Incidence; Isoflurane; Ketamine; Methyl Ethers; Propofol; Sevoflurane

2017
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
    BMC anesthesiology, 2019, 08-01, Volume: 19, Issue:1

    Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theorem; Child; Clonidine; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Humans; Ketamine; Midazolam; Network Meta-Analysis; Ophthalmologic Surgical Procedures; Propofol; Psychomotor Agitation; Remifentanil; Sevoflurane; Sufentanil

2019

Trials

38 trial(s) available for propofol and clonidine

ArticleYear
Total i.v. anaesthesia with propofol and alfentanil: dose requirements for propofol and the effect of premedication with clonidine.
    British journal of anaesthesia, 1990, Volume: 65, Issue:2

    Topics: Administration, Oral; Alfentanil; Anesthesia, Intravenous; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Preanesthetic Medication; Propofol; Temazepam

1990
Epidural clonidine or sufentanil for intraoperative and postoperative analgesia.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Abdomen; Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Clonidine; Consciousness; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Intraoperative Care; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Propofol; Prospective Studies; Sufentanil; Sympatholytics

1995
The effects of clonidine on desflurane-mediated sympathoexcitation in humans.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Action Potentials; Adult; Anesthetics, Inhalation; Blood Pressure; Central Venous Pressure; Clonidine; Desflurane; Heart Rate; Hemodynamics; Humans; Isoflurane; Male; Peroneal Nerve; Propofol; Sympathetic Nervous System; Vecuronium Bromide

1995
[Does clonidine modify the hypnotic effect of propofol?].
    Der Anaesthesist, 1993, Volume: 42, Issue:9

    Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Female; Humans; Hypnosis, Anesthetic; Male; Middle Aged; Propofol

1993
Clonidine increases the sweating threshold, but does not reduce the gain of sweating.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Body Temperature; Body Temperature Regulation; Clonidine; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Intravenous; Male; Muscle, Skeletal; Narcotics; Propofol; Shivering; Skin Temperature; Sodium Chloride; Sweating; Tympanic Membrane

1996
Late intraoperative clonidine administration prevents postanesthetic shivering after total intravenous or volatile anesthesia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Clonidine; Female; Humans; Isoflurane; Male; Middle Aged; Nitrous Oxide; Propofol; Shivering

1997
[The effects of premedication on induction doses of propofol and hemodynamic responses during induction].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:10

    Topics: Adult; Atropine; Clonidine; Diazepam; Drug Interactions; Female; Hemodynamics; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Preanesthetic Medication; Propofol

1997
Effects of premedication on dose requirements for propofol: comparison of clonidine and hydroxyzine.
    British journal of anaesthesia, 1998, Volume: 80, Issue:6

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anesthetics, Intravenous; Anti-Anxiety Agents; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Heart Rate; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Preanesthetic Medication; Propofol; Sympatholytics

1998
The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:8

    Topics: Administration, Oral; Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Breast Neoplasms; Clonidine; Diazepam; Double-Blind Method; Drug Costs; Female; Fentanyl; Hemodynamics; Humans; Infusions, Intravenous; Intubation, Intratracheal; Lymph Node Excision; Mastectomy, Segmental; Middle Aged; Nitrous Oxide; Oxygen; Placebos; Preanesthetic Medication; Propofol

1998
High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General; Clonidine; Coronary Artery Bypass; Epinephrine; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Perioperative Care; Propofol; Prospective Studies; Stress, Physiological; Sufentanil; Sympatholytics; Troponin T

1999
Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Intravenous; Clonidine; Coronary Artery Bypass; Creatinine; Double-Blind Method; Female; Hemodynamics; Humans; Hydrocortisone; Hypertension; Intraoperative Complications; Male; Myocardial Ischemia; Oxygen Consumption; Postoperative Complications; Propofol; Prospective Studies; Quality of Life; Tachycardia

1999
Epidural clonidine or bupivacaine as the sole analgesic agent during and after abdominal surgery: a comparative study.
    Anesthesiology, 1999, Volume: 90, Issue:5

    Topics: Abdomen; Adolescent; Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Bupivacaine; Clonidine; Double-Blind Method; Humans; Middle Aged; Pain, Postoperative; Propofol

1999
Propofol anesthesia enhances pressor response to ephedrine in patients given clonidine.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:1

    Topics: Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Clonidine; Ephedrine; Female; Heart Rate; Humans; Male; Middle Aged; Preanesthetic Medication; Propofol

1999
Oral clonidine premedication reduces induction dose and prolongs awakening time from propofol-nitrous oxide anesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:9

    Topics: Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Clonidine; Electrocardiography; Female; Gynecologic Surgical Procedures; Humans; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Propofol; Time Factors

1999
Haemodynamic effects of intravenous clonidine on propofol or thiopental induction.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Clonidine; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Preanesthetic Medication; Propofol; Thiopental

2000
Effect of epidural and intravenous clonidine on the neuro-endocrine and immune stress response in patients undergoing lung surgery.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Intravenous; beta-Endorphin; Clonidine; Epinephrine; Female; Follow-Up Studies; Humans; Hydrocortisone; Immunity, Cellular; Injections, Epidural; Injections, Intravenous; Leukocyte Count; Lung; Lymphocyte Count; Male; Middle Aged; Morphine; Neurosecretory Systems; Neutrophils; Norepinephrine; Propofol; Stress, Physiological; Sympatholytics; Vasopressins

2000
Oral clonidine premedication reduces propofol requirement for laryngeal mask airway insertion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:7

    Topics: Administration, Oral; Adult; Analgesics; Anesthesia, Inhalation; Anesthetics, Intravenous; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hysterectomy; Laryngeal Masks; Middle Aged; Preanesthetic Medication; Propofol

2000
The effects of clonidine on human digital vasculature.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adult; Alfentanil; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Clonidine; Consciousness; Cross-Over Studies; Female; Fingers; Heart Rate; Humans; Infrared Rays; Injections, Intravenous; Male; Middle Aged; Monitoring, Physiologic; Nitrous Oxide; Plethysmography; Propofol; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents

2000
The efficacy of oral clonidine premedication in the prevention of postoperative vomiting in children following strabismus surgery.
    Paediatric anaesthesia, 2001, Volume: 11, Issue:1

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Antiemetics; Child; Child, Preschool; Clonidine; Diazepam; Double-Blind Method; Female; Humans; Male; Nitrous Oxide; Postoperative Nausea and Vomiting; Preanesthetic Medication; Propofol; Prospective Studies; Strabismus

2001
Orally administered clonidine significantly reduces pain during injection of propofol.
    British journal of anaesthesia, 2001, Volume: 86, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Chi-Square Distribution; Clonidine; Female; Humans; Injections; Middle Aged; Pain; Premedication; Propofol

2001
Clonidine decreases propofol requirements during anaesthesia: effect on bispectral index.
    British journal of anaesthesia, 2001, Volume: 86, Issue:5

    Topics: Adjuvants, Anesthesia; Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Clonidine; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Female; Hemodynamics; Humans; Male; Memory; Middle Aged; Monitoring, Intraoperative; Propofol

2001
The interaction between propofol and clonidine for loss of consciousness.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Anesthetics, Intravenous; Clonidine; Drug Interactions; Humans; Male; Middle Aged; Preanesthetic Medication; Propofol; Unconsciousness

2002
Oral clonidine premedication reduces the EC50 of propofol concentration for laryngeal mask airway insertion in male patients.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Gas Analysis; Clonidine; Drug Interactions; Electrocardiography; Hemodynamics; Humans; Infusions, Intravenous; Laryngeal Masks; Male; Monitoring, Intraoperative; Preanesthetic Medication; Propofol

2002
Remifentanil-clonidine-propofol versus sufentanil-propofol anesthesia for coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 2002, Volume: 16, Issue:6

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Catecholamines; Clonidine; Coronary Artery Bypass; Hemodynamics; Humans; Intraoperative Complications; Male; Middle Aged; Piperidines; Propofol; Remifentanil; Sufentanil

2002
The effects of clonidine premedication on the blood pressure and tachycardiac responses to ephedrine in elderly and young patients during propofol anesthesia.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:1

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Aged; Aging; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Clonidine; Double-Blind Method; Ephedrine; Female; Heart Rate; Humans; Male; Midazolam; Middle Aged; Oxygen; Preanesthetic Medication; Propofol; Tachycardia

2003
[Comparison of premedication with clonidine and midazolam combined with TCI for orthopaedic shoulder surgery].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2003, Volume: 38, Issue:12

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Patient-Controlled; Anesthesia, Conduction; Anesthetics, Intravenous; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Narcotics; Orthopedic Procedures; Pain, Postoperative; Piperidines; Pirinitramide; Postoperative Nausea and Vomiting; Premedication; Propofol; Prospective Studies; Remifentanil; Shoulder

2003
Effect of propofol and clonidine on cerebral blood flow velocity and carbon dioxide reactivity in the middle cerebral artery.
    Journal of neurosurgical anesthesiology, 2004, Volume: 16, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Analysis of Variance; Anesthetics, Combined; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Clonidine; Female; Heart Rate; Humans; Male; Middle Cerebral Artery; Partial Pressure; Propofol; Ultrasonography, Doppler, Transcranial

2004
Clonidine attenuates the hemodynamic responses to hypercapnia during propofol anesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:2

    Topics: Adult; Analgesics; Anesthetics, Intravenous; Clonidine; Drug Synergism; Hemodynamics; Humans; Hypercapnia; Norepinephrine; Preanesthetic Medication; Propofol

2004
Effects of magnesium sulphate and clonidine on propofol consumption, haemodynamics and postoperative recovery.
    British journal of anaesthesia, 2005, Volume: 94, Issue:4

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Anti-Arrhythmia Agents; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Electroencephalography; Female; Heart Rate; Hemodynamics; Humans; Magnesium Sulfate; Male; Middle Aged; Premedication; Propofol; Spine

2005
Effect of clonidine pre-medication on propofol requirements during lower extremity vascular surgery: a randomized controlled trial.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics; Anesthesia; Anesthetics; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Female; Humans; Leg; Male; Middle Aged; Peripheral Vascular Diseases; Preanesthetic Medication; Propofol; Prospective Studies; Statistics, Nonparametric

2005
[Effects of oral clonidine premedication on the heart rate response to intravenous atropine during propofol anesthesia].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:9

    Topics: Administration, Oral; Adult; Analgesics; Anesthetics, Intravenous; Atropine; Clonidine; Female; Heart Rate; Humans; Injections, Intravenous; Male; Preanesthetic Medication; Propofol

2005
Clonidine-ephedrine combination reduces pain on injection of propofol and blunts hemodynamic stress responses during the induction sequence.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:3

    Topics: Analgesics; Anesthetics, Intravenous; Clonidine; Ephedrine; Female; Hemodynamics; Humans; Male; Middle Aged; Pain; Propofol; Prospective Studies; Stress, Physiological

2006
Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement.
    Journal of anesthesia, 2008, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Clonidine; Electroencephalography; Female; Heart Rate; Humans; Male; Metoprolol; Monitoring, Intraoperative; Propofol; Prospective Studies; Treatment Outcome

2008
Intrathecal clonidine decreases propofol sedation requirements during spinal anesthesia in infants.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:7

    Topics: Abdomen; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Clonidine; Double-Blind Method; Drug Therapy, Combination; Elective Surgical Procedures; Female; Fentanyl; Humans; Infant; Injections, Spinal; Male; Propofol; Prospective Studies

2010
An evaluation of intrathecal bupivacaine combined with intrathecal or intravenous clonidine in children undergoing orthopedic surgery: a randomized double-blinded study.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:4

    Topics: Adrenergic alpha-Agonists; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bupivacaine; Child; Clonidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Injections, Spinal; Intraoperative Period; Male; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Postoperative Care; Propofol; Treatment Outcome

2011
Melatonin and clonidine premedication has similar impact on the pharmacokinetics and pharmacodynamics of propofol target controlled-infusions.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Interactions; Female; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Melatonin; Middle Aged; Models, Biological; Poland; Premedication; Propofol; Prospective Studies; Young Adult

2015
Ultrasound-guided bilateral superficial cervical block and preemptive single-dose oral tizanidine for post-thyroidectomy pain: a randomized-controlled double-blind study.
    Journal of anesthesia, 2018, Volume: 32, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Clonidine; Double-Blind Method; Female; Fentanyl; Humans; Male; Middle Aged; Nerve Block; Pain, Postoperative; Propofol; Thyroidectomy

2018
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
    BMC anesthesiology, 2022, 10-24, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution

2022

Other Studies

24 other study(ies) available for propofol and clonidine

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Anesthetics; Animals; Biological Transport; Clonidine; Corpus Striatum; Enflurane; Etomidate; gamma-Aminobutyric Acid; Halothane; In Vitro Techniques; Isoflurane; Ketamine; Male; Nipecotic Acids; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Synaptosomes; Thiopental

1995
Clonidine premedication for induced hypotension with total intravenous anaesthesia for middle ear microsurgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Clonidine; Ear, Middle; Fentanyl; Heart Rate; Humans; Hypotension, Controlled; Meperidine; Microsurgery; Monitoring, Intraoperative; Preanesthetic Medication; Promethazine; Propofol

1994
[Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus].
    Minerva anestesiologica, 1993, Volume: 59, Issue:4

    Topics: Aged; Autonomic Nervous System; Clonidine; Conscious Sedation; Female; Humans; Midazolam; Propofol; Severity of Illness Index; Tetanus

1993
Choices in sedation: the balanced sedation technique.
    European journal of anaesthesiology. Supplement, 1996, Volume: 13

    Topics: Anesthesia, Conduction; Clonidine; Conscious Sedation; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Propofol

1996
Propofol for sedation during rapid opiate detoxification.
    The American journal of psychiatry, 1997, Volume: 154, Issue:2

    Topics: Adult; Clonidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Naloxone; Opioid-Related Disorders; Oxazepam; Propofol; Substance Withdrawal Syndrome

1997
[Interactions of intravenous anesthetics with cerebral alpha-2-adrenoceptors].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1999, Volume: 34, Issue:10

    Topics: Adrenergic alpha-Agonists; Affinity Labels; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Autoradiography; Binding, Competitive; Brain; Clonidine; In Vitro Techniques; Ketamine; Propofol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2

1999
Clonidine premedication decreases propofol consumption during bispectral index (BIS) monitored propofol-ketamine technique for office-based surgery.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2000, Volume: 26, Issue:9

    Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Anesthetics, Intravenous; Antihypertensive Agents; Clonidine; Drug Administration Schedule; Female; Humans; Ketamine; Middle Aged; Preanesthetic Medication; Propofol; Rhytidoplasty

2000
Oral clonidine premedication reduces the awakening concentration of propofol.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:3

    Topics: Administration, Oral; Adult; Anesthetics, Intravenous; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Preanesthetic Medication; Propofol; Wakefulness

2002
Alpha-2 adrenoceptor activity affects propofol-induced sleep time.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:5

    Topics: Anesthetics, Intravenous; Animals; Clonidine; gamma-Aminobutyric Acid; Male; Norepinephrine; Prefrontal Cortex; Propofol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sleep; Yohimbine

2002
[Open heart tricuspid valve replacement in a heroin addict Anaesthesiological management].
    Der Anaesthesist, 2005, Volume: 54, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Amides; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Desflurane; Dipyrone; Female; Heart Valve Prosthesis Implantation; Heroin Dependence; Humans; Isoflurane; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Ropivacaine; Tricuspid Valve

2005
Practice of sedation and analgesia in German intensive care units: results of a national survey.
    Critical care (London, England), 2005, Volume: 9, Issue:2

    Topics: Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Clonidine; Critical Illness; Data Interpretation, Statistical; Drug Therapy, Combination; Fentanyl; Germany; Health Care Surveys; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Practice Guidelines as Topic; Propofol; Sufentanil; Surveys and Questionnaires

2005
[Hemodynamic reaction attended safety in severe head injury patients at different periods of operative treatment].
    Vestnik khirurgii imeni I. I. Grekova, 2005, Volume: 164, Issue:1

    Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Blood Circulation; Clonidine; Craniocerebral Trauma; Fentanyl; Glasgow Coma Scale; Hemodynamics; Homeostasis; Humans; Hypnotics and Sedatives; Propofol; Thiopental

2005
[Effects of induction of anesthesia on hemodynamics in children with deformities of the spinal cord when turning to the position lying on the belly].
    Vestnik khirurgii imeni I. I. Grekova, 2005, Volume: 164, Issue:1

    Topics: Adolescent; Age Factors; Analgesics; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Clonidine; Fentanyl; Hemodynamics; Humans; Ketamine; Kyphosis; Nitrous Oxide; Prone Position; Propofol; Respiration, Artificial; Scoliosis; Spinal Injuries; Spinal Neoplasms; Thiopental

2005
Clonidine elicits a long-term depression in mucosal red cell flux.
    Advances in experimental medicine and biology, 2007, Volume: 599

    Topics: Adrenergic alpha-Agonists; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Cardiac Output; Clonidine; Dogs; Erythrocytes; Heart Rate; Humans; Methyl Ethers; Mucous Membrane; Propofol; Sevoflurane

2007
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiography; Energy Metabolism; Female; Hemodynamics; Humans; Hypertension; Hypnotics and Sedatives; Male; Oxygen Consumption; Piperidines; Propofol; Prospective Studies; Remifentanil; Respiration, Artificial; Respiratory Insufficiency; Rest; Substance Withdrawal Syndrome; Tachycardia; Ventilator Weaning

2009
Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:8

    Topics: Abdominal Abscess; Adrenergic alpha-2 Receptor Agonists; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Bupivacaine; Clonidine; Colectomy; Delirium; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Pain, Postoperative; Postoperative Complications; Propofol; Young Adult

2012
Scalp blocks in nonsyndromic craniosynostosis surgery - a retrospective case series review.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:8

    Topics: Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Clonidine; Craniosynostoses; Female; Humans; Infant; Male; Methyl Ethers; Nerve Block; Nitrous Oxide; Piperidines; Propofol; Remifentanil; Retrospective Studies; Scalp; Sevoflurane

2014
Acute presentation of a partially obstructing laryngeal tumour: adjuvant agents to gaseous induction of anaesthesia.
    BMJ case reports, 2018, Jul-12, Volume: 2018

    Topics: Airway Management; Airway Obstruction; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Adenosquamous; Clonidine; Humans; Intubation, Intratracheal; Laryngeal Neoplasms; Laryngoscopy; Male; Methyl Ethers; Middle Aged; Propofol; Sevoflurane; Tomography, X-Ray Computed

2018
Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality.
    Revista gaucha de enfermagem, 2020, Volume: 41

    Topics: Analgesics; Chi-Square Distribution; Clonidine; Critical Care; Cross-Sectional Studies; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Prevalence; Propofol

2020