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propofol and 4-iodo-2,6-diisopropylphenol

propofol has been researched along with 4-iodo-2,6-diisopropylphenol in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altomare, C; Biggio, G; Franco, M; Latrofa, A; Liso, G; Sanna, E; Trapani, G; Usala, M1
Harrison, NL; Hong, X; Hopfinger, AJ; Krasowski, MD1
Dong, X; Ebalunode, JO; Eckenhoff, RG; Liang, J; Ouyang, Z; Zheng, W1
Biggio, G; Dazzi, L; Latrofa, A; Liso, G; Maciocco, E; Motzo, C; Sanna, E; Serra, M; Trapani, G; Usala, M1
Blackbeer, J; Giunta, AL; Harrison, NL; Hemmings, HC; Jenkins, A; Krasowski, MD; Lingamaneni, R; MacIver, MB; Truong, T1

Other Studies

5 other study(ies) available for propofol and 4-iodo-2,6-diisopropylphenol

ArticleYear
Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Anesthetics, Intravenous; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channel Agonists; Female; Humans; In Vitro Techniques; Oocytes; Patch-Clamp Techniques; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis

1998
4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor.
    Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15

    Topics: Algorithms; Anesthetics, General; Animals; Binding Sites; Excitatory Amino Acid Agonists; Humans; Hydrophobic and Hydrophilic Interactions; Larva; Ligands; Models, Molecular; Propofol; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis

2002
Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Anesthetics; Animals; Apoferritins; Binding Sites; Crystallography, X-Ray; Horses; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Structure-Activity Relationship

2009
Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: Acetylcholine; Anesthetics; Animals; Anti-Anxiety Agents; Anticonvulsants; Chloride Channels; Conflict, Psychological; Dose-Response Relationship, Drug; Electrophysiology; Exploratory Behavior; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Membrane Potentials; Mice; Oocytes; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Xenopus

1999
Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
    Anesthesiology, 2001, Volume: 94, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Synaptosomes; Xenopus laevis

2001