Page last updated: 2024-08-21

propiolaldehyde and pargyline

propiolaldehyde has been researched along with pargyline in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeMaster, EG; Nagasawa, HT; Shirota, FN3
DeMaster, EG; Elberling, JA; Nagasawa, HT1
DeMaster, EG; Nagasawa, HT1
DeMaster, EG; Kaplan, E; Nagasawa, HT; Shirota, FN; Sumner, HW1

Other Studies

6 other study(ies) available for propiolaldehyde and pargyline

ArticleYear
Propiolaldehyde, a pargyline metabolite that irreversibly inhibits aldehyde dehydrogenase. Isolation from a hepatic microsomal system.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:5

    Topics: Aldehyde Oxidoreductases; Aldehydes; Animals; Biotransformation; In Vitro Techniques; Male; Microsomes, Liver; Mitochondria, Liver; Pargyline; Phenobarbital; Rats

1979
Latent inhibitors of aldehyde dehydrogenase as alcohol deterrent agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:10

    Topics: Alcoholism; Aldehyde Dehydrogenase; Animals; Chemical Phenomena; Chemistry; Ethanol; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mitochondria, Liver; Pargyline; Rats; Structure-Activity Relationship

1984
Inhibition of aldehyde dehydrogenase by propiolaldehyde, a possible metabolite of pargyline.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 21, Issue:3

    Topics: Acetylcholine; Aldehyde Oxidoreductases; Aldehydes; Alkynes; Animals; Male; Mitochondria, Liver; Pargyline; Proadifen; Rats; Time Factors

1978
Role of propiolaldehyde and other metabolites in the pargyline inhibition of rat liver aldehyde dehydrogenase.
    Biochemical pharmacology, 1986, May-01, Volume: 35, Issue:9

    Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Carbon Monoxide; Cobalt; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Hydroxylation; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Pargyline; Rats; Rats, Inbred Strains; Time Factors

1986
Pargyline-induced hepatotoxicity: possible mediation by the reactive metabolite, propiolaldehyde.
    Toxicology and applied pharmacology, 1982, Sep-30, Volume: 65, Issue:3

    Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Pargyline; Proadifen; Rats; Rats, Inbred Strains

1982
Microsomal N-depropargylation of pargyline to propiolaldehyde, an irreversible inhibitor of mitochondrial aldehyde dehydrogenase.
    Advances in experimental medicine and biology, 1980, Volume: 132

    Topics: Aldehyde Oxidoreductases; Aldehydes; Animals; Biotransformation; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoenzymes; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; Pargyline; Phenobarbital; Proadifen; Rats

1980