propidium iodide has been researched along with tacrine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erlanson, DA; McDowell, RS; O'Brien, T | 1 |
| Andrisano, V; Banzi, R; Bartolini, M; Bolognesi, ML; Melchiorre, C | 1 |
| Andrisano, V; Bartolini, M; Bidon-Chanal, A; de Austria, C; del Monte-Millán, M; Dorronsoro, I; García-Palomero, E; Luque, FJ; Martínez, A; Medina, M; Muñoz-Ruiz, P; Orozco, M; Rubio, L; Usán, P; Valenzuela, R | 1 |
| Andrisano, V; Banzi, R; Bartolini, M; Bergamini, C; Bolognesi, ML; Cattaneo, A; Cavalli, A; Fato, R; Hrelia, P; Lenaz, G; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tarozzi, A; Tumiatti, V | 1 |
| Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V | 1 |
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
| Barril, X; de los Ríos, C; García, AG; Huertas, O; León, R; López, MG; Luque, FJ; Marco-Contelles, J; Villarroya, M | 1 |
| Gu, LQ; Huang, SL; Huang, ZS; Ma, L; Ning, FX; Qiao, W; Tang, H; Wei, YB; Zhang, C | 1 |
| Lv, W; Xue, Y | 1 |
| Arnold, N; Brandt, W; Geissler, T; Kehlen, A; Porzel, A; Schlenzig, D; Wessjohann, L | 1 |
| Guillou, C; Iorga, BI; Rouleau, J | 1 |
| Mohamed, T; Rao, PP; Yeung, JC | 1 |
| Bolea, I; Chioua, M; de Los Ríos, C; Juárez-Jiménez, J; Luque, FJ; Marco-Contelles, J; Pouplana, R; Samadi, A; Unzeta, M | 1 |
| Andrisano, V; Badia, A; Bartolini, M; Bidon-Chanal, A; Camps, P; Clos, MV; Formosa, X; Galdeano, C; González-Muñoz, GC; Luque, FJ; Mancini, F; Minguillón, C; Muñoz-Torrero, D; Ratia, M; Relat, J; Rodríguez-Franco, MI; Salmona, M; Sola, I; Viayna, E | 1 |
| Chen, ZF; Liang, H; Tang, H; Wang, ZY; Zhao, HT; Zhong, SM | 1 |
| Cao, H; Chen, JG; Guan, XL; Jiang, FC; Li, L; Li, MX; Wang, CM; Wang, F; Wang, Y; Yu, JP | 1 |
| Chen, SB; Gu, LQ; He, Y; Huang, SL; Huang, ZH; Huang, ZS; Li, D; Tan, JH; Yao, PF | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Azzouz, R; Bohn, P; Gembus, V; Levacher, V; Papamicaël, C; Peauger, L; Sopková-de Oliveira Santos, J; Ţînţaş, ML | 1 |
2 review(s) available for propidium iodide and tacrine
| Article | Year |
|---|---|
Fragment-based drug discovery.
Topics: Animals; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Weight; Protein Binding; Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Multi-target-directed ligands to combat neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid | 2008 |
17 other study(ies) available for propidium iodide and tacrine
| Article | Year |
|---|---|
Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Biochemistry; Cholinesterase Inhibitors; Dimerization; Drug Design; Drug Evaluation, Preclinical; Fluorometry; Humans; Hydrolysis; Inhibitory Concentration 50; Ligands; Polyamines; Propidium; Structure-Activity Relationship | 2005 |
Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cell Line, Tumor; Cholinesterase Inhibitors; Dimerization; Drug Design; Erythrocytes; Fluorometry; Humans; Models, Molecular; Nootropic Agents; Protein Binding; Structure-Activity Relationship; Tacrine | 2005 |
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Butyrylcholinesterase; Cell Line; Cholinesterase Inhibitors; Humans; Ligands; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Polyamines; Protein Binding; Quinones; Reactive Oxygen Species; Structure-Activity Relationship; Substrate Specificity | 2007 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties.
Topics: Acetylcholinesterase; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dihydropyridines; Humans; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Neuroprotective Agents; Reactive Oxygen Species; Spectrophotometry, Infrared; Tacrine | 2008 |
Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.
Topics: Acetylcholinesterase; Alkaloids; Animals; Aporphines; Butyrylcholinesterase; Computer Simulation; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Models, Chemical; Models, Molecular; Molecular Structure; Reproducibility of Results; Stereoisomerism; Torpedo | 2009 |
Prediction of acetylcholinesterase inhibitors and characterization of correlative molecular descriptors by machine learning methods.
Topics: Algorithms; Artificial Intelligence; Cholinesterase Inhibitors; Computational Biology; Drug Design; Models, Chemical; Quantitative Structure-Activity Relationship | 2010 |
Acetylcholinesterase inhibitors from the toadstool Cortinarius infractus.
Topics: Acetylcholinesterase; Agaricales; Animals; Cattle; Cholinesterase Inhibitors; Erythrocytes; Fruiting Bodies, Fungal; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
New potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid β aggregation.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2011 |
Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aβ-aggregation inhibitors: Synthesis and biological evaluation.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzhydryl Compounds; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Parkinson Disease; Plaque, Amyloid; Pyrimidines; Structure-Activity Relationship | 2011 |
Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's di
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Donepezil; Electrophorus; Horses; Humans; Indans; Indoles; Isoenzymes; Kinetics; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Piperidines; Rats; Structure-Activity Relationship | 2011 |
Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Amyloid beta-Peptides; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Membranes, Artificial; Mice; Models, Molecular; Peptide Fragments; Permeability; Prion Diseases; Prions; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Tacrine | 2012 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Membranes, Artificial; Models, Molecular; Molecular Structure; Permeability; Protein Binding | 2012 |
Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, β-amyloid aggregation and Ca²⁺ overload.
Topics: Amyloid beta-Peptides; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Molecular Structure; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tacrine; Thiazoles | 2012 |
Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Biocatalysis; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indole Alkaloids; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Quinazolines | 2013 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Animals; Cholinesterase Inhibitors; Donepezil; Drug Design; Female; Humans; Indans; Mice; Molecular Docking Simulation; Piperidines; Prodrugs | 2017 |