Compounds > propidium
Page last updated: 2024-08-16

propidium and tacrine

propidium has been researched along with tacrine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA1
Dodds, HM; Rivory, LP1
Aldunate, R; Inestrosa, NC; Muñoz, FJ1
Cusack, B; Fauq, A; Hughes, TF; Johnson, JL; McCullough, EH; Romanovskis, P; Rosenberry, TL; Spatola, AF1
Alonso, D; Castro, A; del Monte, M; Dorronsoro, I; García-Palomero, E; Martínez, A1
de los Ríos, C; García, AG; León, R; López, MG; Marco-Contelles, J; Villarroya, M1
Bajda, M; Malawska, B; Musiał, A1
Conde, S; Fernández-Bachiller, MI; García, AG; González-Muñoz, GC; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M1

Reviews

1 review(s) available for propidium and tacrine

ArticleYear
Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment.
    Current medicinal chemistry, 2007, Volume: 14, Issue:25

    Topics: Alkaloids; Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Indole Alkaloids; Isoquinolines; Phenylcarbamates; Physostigmine; Piperidines; Propidium; Rivastigmine; Steroids; Tacrine

2007

Other Studies

7 other study(ies) available for propidium and tacrine

ArticleYear
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
    Biochemistry, 2013, Oct-22, Volume: 52, Issue:42

    Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity

2013
The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11).
    Molecular pharmacology, 1999, Volume: 56, Issue:6

    Topics: Acetylcholinesterase; Acylation; Alzheimer Disease; Binding, Competitive; Butyrylcholinesterase; Camptothecin; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hydrolysis; Irinotecan; Kinetics; Neostigmine; Propidium; Substrate Specificity; Tacrine

1999
Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase.
    Neuroreport, 1999, Nov-26, Volume: 10, Issue:17

    Topics: Acetylcholinesterase; Animals; Binding Sites; Cell Division; Cells, Cultured; Cholinesterase Inhibitors; DNA; Dose-Response Relationship, Drug; Edrophonium; Formazans; Gallamine Triethiodide; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Propidium; Protein Structure, Tertiary; Rats; Spinal Cord; Tacrine; Tetrazolium Salts

1999
Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Acetylcholinesterase; Binding Sites; Cations; Cysteine; Disulfides; Dose-Response Relationship, Drug; Humans; Hydrolysis; Kinetics; Ligands; Models, Chemical; Models, Molecular; Models, Statistical; Mutagenesis, Site-Directed; Mutation; Propidium; Protein Binding; Recombinant Proteins; Tacrine

2003
Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors.
    Archiv der Pharmazie, 2005, Volume: 338, Issue:1

    Topics: Acetylcholinesterase; Animals; Binding, Competitive; Cattle; Cell Line, Tumor; Cholinesterase Inhibitors; Erythrocytes; Humans; In Vitro Techniques; Propidium; Structure-Activity Relationship; Tacrine; Thiadiazoles

2005
New multipotent tetracyclic tacrines with neuroprotective activity.
    Bioorganic & medicinal chemistry, 2006, Dec-15, Volume: 14, Issue:24

    Topics: Acetylcholinesterase; Calcium; Cholinesterase Inhibitors; Cytosol; Humans; L-Lactate Dehydrogenase; Molecular Structure; Neuroblastoma; Neuroprotective Agents; Propidium; Structure-Activity Relationship; Tacrine; Tumor Cells, Cultured

2006
Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Journal of medicinal chemistry, 2010, Jul-08, Volume: 53, Issue:13

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cholinesterase Inhibitors; Copper; Humans; Hydroxyquinolines; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Propidium; Spectrometry, Mass, Electrospray Ionization; Tacrine

2010