propentofylline has been researched along with adenosine in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (16.22) | 18.7374 |
| 1990's | 26 (70.27) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ishikawa, A; Miyashita, K; Miyatake, T; Nakajima, T | 1 |
| Fastbom, J; Fredholm, BB; Gerwins, P; Kvanta, A; Parkinson, F | 1 |
| Fredholm, BB; Parkinson, FE | 1 |
| Hada, J; Hayakawa, T; Hayashi, Y; Morimoto, K; Nii, Y; Shimada, N; Shimizu, H | 1 |
| Mitsumoto, Y; Mohri, T; Ohkubo, T | 1 |
| Haraguchi, H; Kuribara, H | 1 |
| Dux, E; Fastbom, J; Fredholm, BB; Rudolphi, K; Ungerstedt, U | 1 |
| Brown, MD; Hudlická, O | 1 |
| Dunér-Engström, M; Fredholm, BB | 1 |
| Fredholm, BB; Lindström, K | 1 |
| DeLeo, J; Kreutzberg, GW; Schubert, P | 1 |
| Hudlicka, O; Tyler, KR; Wright, AJ; Ziada, AM | 1 |
| Fitzgibbons, JC; Gidday, JM; Kraujalis, MJ; Park, TS; Shah, AR | 1 |
| Fredholm, BB; Zhang, Y | 1 |
| Park, CK; Rudolphi, KA | 1 |
| Nakamura, H; Okada, Y; Yamada, Y | 1 |
| Fredholm, BB; Parkinson, FE; Rudolphi, KA | 1 |
| Fredholm, BB; Lindström, K; Wallman-Johansson, A | 1 |
| Cass, CE; Parkinson, FE; Paterson, AR; Young, JD | 1 |
| Figge, C; Godehardt, E; Kolvenbach, R; Sandmann, W | 1 |
| Kataoka, K; Nakamura, Y; Rudolphi, K; Schubert, P; Si, QS | 1 |
| Kozaki, K; Kozaki, M; Matsuno, N | 1 |
| Fredholm, BB; Johansson, B; Lindström, K; Parkinson, FE | 1 |
| Geiger, JD; Mukherjee, K; Parkinson, FE | 1 |
| Kataoka, K; Nakamura, Y; Si, QS | 1 |
| O'Regan, MH; Phillis, JW | 1 |
| Kittner, B; Rössner, M; Rother, M | 1 |
| Ferroni, S; Marchini, C; McRae, A; Ogata, T; Rudolphi, K; Schubert, P | 1 |
| Kapl, D; Rudolphi, KA | 1 |
| Flavin, MP; Ho, LT | 1 |
| Borgland, SL; Castañón, M; Parkinson, FE; Spevak, W | 1 |
| Martinez-Tica, JF; Zornow, MH | 1 |
| Bardenheuer, HJ; Grant, M; Martin, E; Plaschke, K; Weigand, MA; Züchner, J | 1 |
| Leskovac, V | 1 |
| Bai, X; Chen, F; Cui, M; Dong, Q; Li, T; Liu, X; Zhao, Y | 1 |
| Lis, M; Obmińska-Mrukowicz, B; Pawlak, A; Suszko-Pawłowska, A; Sysak, A; Szczypka, M | 1 |
4 review(s) available for propentofylline and adenosine
| Article | Year |
|---|---|
Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia.
Topics: Adenosine; Animals; Biological Transport; Brain Ischemia; Cells, Cultured; Cerebrovascular Circulation; Depression, Chemical; Excitatory Amino Acid Antagonists; Gerbillinae; Humans; Receptors, Purinergic P1; Xanthines | 1994 |
Clinical trials in dementia with propentofylline.
Topics: Adenosine; Aged; Alzheimer Disease; Clinical Trials, Phase III as Topic; Dementia, Vascular; Double-Blind Method; Female; Humans; Male; Meta-Analysis as Topic; Neuroprotective Agents; Randomized Controlled Trials as Topic; Xanthines | 1997 |
Support of homeostatic glial cell signaling: a novel therapeutic approach by propentofylline.
Topics: Adenosine; Alzheimer Disease; Astrocytes; Calcium; Cyclic AMP; Homeostasis; Humans; Models, Biological; Molecular Mimicry; Neuroglia; Second Messenger Systems; Signal Transduction; Xanthines | 1997 |
[New pharmacologic aspects in the neurologic profile of propentofylline (Karsivan ad us. vet.)].
Topics: Adenosine; Alzheimer Disease; Animals; Cerebrovascular Circulation; Cognition Disorders; Dementia, Vascular; Dog Diseases; Dogs; Hemodynamics; Humans; Neuroprotective Agents; Phosphodiesterase Inhibitors; Xanthines | 1998 |
33 other study(ies) available for propentofylline and adenosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
An adenosine uptake blocker, propentofylline, reduces glutamate release in gerbil hippocampus following transient forebrain ischemia.
Topics: Adenosine; Amino Acids; Animals; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Male; Taurine; Xanthines | 1992 |
Further evidence that propentofylline (HWA 285) influences both adenosine receptors and adenosine transport.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Autoradiography; Biological Transport; Brain Chemistry; Cell Line; Cerebral Cortex; Cricetinae; Guinea Pigs; Humans; Leukemia, T-Cell; Male; Mesocricetus; Muscle, Smooth; Pheochromocytoma; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Tumor Cells, Cultured; Xanthines | 1992 |
Effects of propentofylline on adenosine A1 and A2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: quantitative autoradiographic analysis.
Topics: Adenosine; Animals; Autoradiography; Binding Sites; Brain; Carrier Proteins; Male; Membrane Proteins; Nucleoside Transport Proteins; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thioinosine; Xanthines | 1991 |
Effect of adenosine agonist (propentofylline) on rat hippocampal seizures induced by microdialysis with potassium: analysis using compressed EEG power spectrum array.
Topics: Adenosine; Animals; Electroencephalography; Evoked Potentials; Hippocampus; Male; Potassium; Rats; Rats, Inbred Strains; Seizures; Signal Processing, Computer-Assisted; Theophylline; Xanthines | 1991 |
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines | 1991 |
Behavioral effects of adenosine agonists: evaluation by punishment, discrete shuttle avoidance and activity tests in mice.
Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenylisopropyladenosine; Punishment; Reinforcement Schedule; Xanthines | 1991 |
Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus.
Topics: Adenosine; Animals; Gerbillinae; Ischemic Attack, Transient; Male; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Cardiac work and capillary density in normal and vascularly compromised hearts.
Topics: Adenosine; Animals; Blood Pressure; Capillaries; Cardiomegaly; Endocardium; Female; Heart; Heart Rate; Male; Myocardial Infarction; Necrosis; Norepinephrine; Organ Size; Rabbits; Xanthines | 1989 |
Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Animals; Cyclic AMP; Dipyridamole; Hippocampus; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
The xanthine derivative 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine (HWA 285) enhances the actions of adenosine.
Topics: Adenosine; Animals; Biological Transport; Caffeine; Cyclic AMP; Drug Synergism; Erythrocyte Membrane; Hippocampus; Humans; Pentoxifylline; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theobromine; Xanthines | 1986 |
Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist.
Topics: Adenosine; Animals; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Pyramidal Tracts; Reference Values; Theophylline; Xanthines | 1988 |
The effect of long-term vasodilatation on capillary growth and performance in rabbit heart and skeletal muscle.
Topics: Adenosine; Animals; Body Weight; Capillaries; Coronary Circulation; Coronary Vessels; Female; Heart; Hemodynamics; Male; Muscles; Organ Size; Rabbits; Regional Blood Flow; Time Factors; Vasodilation; Xanthines | 1984 |
Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Neuroprotective Agents; Organ Size; Pentostatin; Rats; Rats, Sprague-Dawley; Xanthines | 1995 |
Propentofylline enhancement of the actions of adenosine on neutrophil leukocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Drug Synergism; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Purinergic P1 Receptor Antagonists; Respiratory Burst; Xanthines | 1994 |
Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats.
Topics: Adenosine; Animals; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Male; Nervous System; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Xanthines | 1994 |
Propentofylline enhances the formation of long-term potentiation in guinea pig hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xanthines | 1994 |
Propentofylline and other adenosine transport inhibitors increase the efflux of adenosine following electrical or metabolic stimulation of rat hippocampal slices.
Topics: Adenosine; Animals; Biological Transport; Electric Stimulation; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; Male; Purines; Rats; Rats, Sprague-Dawley; Xanthines | 1994 |
Inhibitory effects of propentofylline on [3H]adenosine influx. A study of three nucleoside transport systems.
Topics: Adenosine; Animals; Biological Transport; Brain Ischemia; Cell Line; Mice; Rats; Thioinosine; Tritium; Tumor Cells, Cultured; Xanthines | 1993 |
Adenosine agonists and global cerebral ischaemia.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Male; Rats; Rats, Wistar; Xanthines | 1993 |
Adenosine and propentofylline inhibit the proliferation of cultured microglial cells.
Topics: Adenosine; Animals; Anti-Ulcer Agents; Cells, Cultured; Dose-Response Relationship, Drug; Microglia; Radioligand Assay; Rats; Thymidine; Xanthines | 1996 |
Beneficial effects of pentoxifylline and propentofylline on preservation-reperfusion injury in rat liver transplantation.
Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Anti-Ulcer Agents; Biomarkers; Glutathione; Insulin; Liver; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Pentoxifylline; Raffinose; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha; Vasodilator Agents; Xanthines | 1996 |
Adenosine A1 and A2A receptors and nitrobenzylthioinosine-sensitive transporters in gerbil brain: no changes following long-term treatment with the adenosine transport inhibitor propentofylline.
Topics: Adenosine; Animals; Anti-Ulcer Agents; Autoradiography; Binding, Competitive; Brain; Gerbillinae; Guanosine Triphosphate; In Situ Hybridization; Receptors, Purinergic P1; Xanthines | 1996 |
[3H]adenosine transport in DDT1 MF-2 smooth muscle cells: inhibition by metabolites of propentofylline.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Cricetinae; Dilazep; Dipyridamole; Genital Neoplasms, Male; Kinetics; Leiomyosarcoma; Leukemia L1210; Male; Mesocricetus; Muscle, Smooth; Rats; Thioinosine; Tumor Cells, Cultured; Vas Deferens; Xanthines | 1996 |
Adenosine inhibits superoxide production in rat peritoneal macrophages via elevation of cAMP level.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Bucladesine; Cyclic AMP; Enzyme Activation; Intracellular Fluid; Macrophages, Peritoneal; Male; Protein Kinase C; Rats; Rats, Wistar; Superoxides; Xanthines | 1997 |
Effects of an inhibitor of adenosine deaminase, deoxycoformycin, and of nucleoside transport, propentofylline, on post-ischemic recovery of adenine nucleotides in rat brain.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Ischemic Attack, Transient; Male; Microwaves; Pentostatin; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors; Xanthines | 1996 |
Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Fetus; Hippocampus; Macrophages, Peritoneal; Mice; Microglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
Effects of propentofylline on adenosine receptor activity in Chinese hamster ovary cell lines transfected with human A1, A2A, or A2B receptors and a luciferase reporter gene.
Topics: Adenosine; Animals; CHO Cells; Colforsin; Cricetinae; Genes, Reporter; Humans; Luciferases; Neuroprotective Agents; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Transfection; Xanthines | 1998 |
Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Electroencephalography; Extracellular Space; Glutamic Acid; Hippocampus; Hypothermia, Induced; Injections, Intravenous; Microdialysis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion; Theophylline; Xanthines | 2000 |
Neuromodulatory effect of propentofylline on rat brain under acute and long-term hypoperfusion.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Brain; Brain Ischemia; Carotid Arteries; Cyclic AMP; Energy Metabolism; Interleukin-1; Male; Memory; Microglia; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthines | 2001 |
Inhibition of Na,K-dependent adenosine triphosphatase by adenosine in intact pigeon erythrocytes.
Topics: Adenosine; Animals; Columbidae; Dipyridamole; Erythrocytes; In Vitro Techniques; Kinetics; Potassium; Sodium-Potassium-Exchanging ATPase; Theobromine; Xanthines | 1983 |
Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cerebrovascular Circulation; Equilibrative Nucleoside Transport Proteins; Extracellular Space; Hypoxia; Hypoxia-Inducible Factor 1; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Mice; Neurons; Neuroprotective Agents; Receptor, Adenosine A1; Regional Blood Flow; Xanthines | 2013 |
Propentofylline, phosphodiesterase and adenosine reuptake inhibitor modulates lymphocyte subsets and lymphocyte activity after in-vivo administration in non-immunized and SRBC-immunized mice.
Topics: Adenosine; Animals; Erythrocytes; Female; Immunity, Humoral; Interleukin-5; Lymph Nodes; Lymphocyte Subsets; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Phosphodiesterase Inhibitors; Sheep; Spleen; T-Lymphocytes, Regulatory; Thymocytes; Time Factors; Xanthines | 2017 |