Page last updated: 2024-08-16

propafenone and quinidine

propafenone has been researched along with quinidine in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (26.32)	18.7374
1990's	29 (30.53)	18.2507
2000's	28 (29.47)	29.6817
2010's	9 (9.47)	24.3611
2020's	4 (4.21)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Pajeva, IK; Wiese, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y	1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Dalvie, D; Loi, CM; Smith, DA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Arnold, E; De Clercq, E; Fang, Z; Feng, D; Kang, D; Liu, X; Pannecouque, C; Pilch, A; Ruiz, FX; Sun, Y; Wang, Z; Wei, F; Zhan, P; Zhao, T	1
Bertagnin, C; Du, R; Guizzo, L; Hou, L; Huang, B; Jia, R; Ju, H; Kang, D; Kong, X; Li, P; Liu, X; Loregian, A; Ma, X; Murugan, NA; Poongavanam, V; Zhan, P; Zhang, Y	1
Castro, I; de Brito, FS; Maia, IG; Pereira, MH	1
Baĭer, T; Brakhmann, I; Khilbel, T; Kiubler, V; Shmitt, K; Valdeker, B	1
Lu, F; Mei, BY; Zhang, XM	1
Deiwick, M; Konertz, W; Scheld, HH; Weyand, M	1
Brusca, A; Comba Costa, G; Gaita, F; Gaschino, G; Greco, C; Richiardi, E; Rosettani, E	1
Benz, I; Kohlhardt, M	2
Hansen, JF; Madsen, JK; Nielsen, H; Rasmussen, V; Sørum, C	1
Gillis, AM; Keashly, R	1
Cohen, JM; Gillis, AM; Hii, JT; Mitchell, LB; Wyse, DG	1
Bauernfeind, RA; Welch, WJ	1
Grant, AO; Starmer, CF	1
Funck-Brentano, C; Kroemer, HK; Pavlou, H; Roden, DM; Woosley, RL	1
Bobbio, M; Bocchiardo, M; Gaita, F; Uslenghi, E; Vado, A	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Amiel, A; Boutaud, P; Ciber, M; Demange, J; Guillem, JP; Herpin, D; Maarek-Charbit, M	1
Huang, SK; Marcus, FI	1
Allessie, MA; Bonke, FI; Lammers, WJ; Rensma, PL; Schalij, MJ	1
Fenster, PE; Horwitz, L; Huang, SK; Kirsten, EB; Klein, RC; Marcus, FI; Rushforth, N	1
Alboni, P; Candini, GC; Cappato, R; Paparella, N; Pirani, R	1
Baker, BJ; deSoyza, N; Dinh, HA; Franciosa, JA; Murphy, ML	1
Hirosawa, K; Kasanuki, H; Onishi, S	1
Podrid, PJ	1
Atarashi, H; Hayakawa, H	1
Graboys, TB; Lampert, S; Lown, B; Podrid, PJ	1
Schmitz, W	1
Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P	1
Somberg, JC	1
Ceci, V; Di Marcotullio, G; Dini, P; Milazzotto, F; Polizzi, C; Santini, M	1
Accettura, D; De Nicolò, M; De Toma, L; Lagioia, R; Mangini, SG; Rizzon, P; Scrutinio, D	1
Assayag, P; Coumel, P; Leclercq, JF	1
De Nicolò, M; De Toma, L; Lagioia, R; Mangini, SG; Rizzon, P; Scrutinio, D	1
Ledda, F; Mantelli, L; Manzini, S; Mugelli, A	1
Grey, E; Silverman, DI	1
Bachernegg, M; Decrinis, M; Domanowits, H; Kickenweiz, E; Laggner, AN; Stark, G; Stark, U; Sterz, F; Tritthart, HA	1
Fernández del Pozo, B; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F	1
Mörike, KE; Roden, DM	1
Castle, NA; Slawsky, MT	1
Boriani, G; Capucci, A; Della Casa, S; Magnani, B; Rubino, I; Sanguinetti, M	1
Cowan, JC	1
Lüderitz, B; Manz, M	1
Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R	1
Ebner, T; Eichelbaum, M	1
Roden, DM	1
Arrigo, F; Cavallaro, L; Coglitore, A; Fazio, F; Oreto, G; Saporito, F; Satullo, G; Sorrenti, S	1
Chang, MS; Chen, SA; Chiang, CE; Lee, SH; Tai, CT; Wang, SP; Wen, ZC	1
Di Benedetto, S	1
Beurrier, D; Brembilla-Perrot, B; Danchin, N; Houplon, P; Jacquemin, L; Louis, P; Terrier de la Chaise, A	1
Bellandi, F; Cantini, F; Dabizzi, RP; Mugnaioni, G; Palchetti, R	1
Capucci, A	1
Epstein, LM; Huang, DT; Josephson, ME; Monahan, KM; Papageorgiou, P; Zimetbaum, P	1
Aschieri, D; Capucci, A; Piepoli, M; Villani, GQ	1
Dell'Orfano, JT; Luck, JC; Naccarelli, GV; Patel, HM; Wolbrette, DL	1
Ishii, K; Kubota, Y; Moriuchi, H; Nakahara, T; Sakamato, K; Shigenobu, K; Tanaka, Y; Yunoki, M	1
Chow, MS; Fan, C; Lau, CP; Tang, MO; Tse, HF	1
Hancox, JC; Paul, AA; Witchel, HJ	1
Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL	1
Kao, W; Kowey, PR; Winkel, E; Yan, GX	1
Furuichi, K; Inamura, K; Kitada, C; Matsushime, H; Miyake, A; Mochizuki, S; Nozawa, K; Okada, H; Sano, Y; Yokoi, H	1
BORIS, A; MOE, RA; SCHALLEK, WE	1
Borbély, M; Dani, G; Erdej, F; Hajdara, I; Katona, A; Márk, L; Nagy, E; Sziklai, G	1
Dorian, P; Humphries, KH; Kerr, CR; Steinbuch, M	1
Amor, F; Charisius, M; Plass, H; Turnheim, K; Wiener, H; Wyskovsky, W	1
Iwaki, M; Komura, H	1
Scharf, C	1
Bakula, M; Frank, B; Gavranovic, Z; Milicevic, G; Pazur, V	1
Daubert, JP	1
Kochanowski, J; Kosior, DA; Opolski, G; Piatkowski, R; Postuła, M; Rabczenko, D; Scisło, P	1
Champagne, J; Charbonneau, L; Geelen, P; Gilbert, M; Hamelin, BA; Michaud, V; O'Hara, GE; Philippon, F; Pruneau, G; Turgeon, J	1
Bai, J; Gao, M; Lo, A; Lu, Y; Zhang, H; Zhao, J; Zhu, Y	1
Belhassen, B; Biton, Y; Mowaswes, M	1

Reviews

12 review(s) available for propafenone and quinidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)]. Klinische Wochenschrift, 1980, Sep-15, Volume: 58, Issue:18 Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide	1980
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy. European heart journal, 1993, Volume: 14 Suppl E Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil	1993
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock]. Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; Electric Countershock; Flecainide; Humans; Propafenone; Quinidine; Recurrence; Sotalol	1993
Is there a need for new antiarrhythmic drugs? Archives des maladies du coeur et des vaisseaux, 1996, Volume: 89 Spec No 1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Conduction System; Humans; Propafenone; Quinidine; Sotalol; Torsades de Pointes	1996
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy. The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit Analysis; Echocardiography, Transesophageal; Electric Countershock; Flecainide; Humans; Procainamide; Propafenone; Quinidine; Sotalol; Verapamil	2000
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Trials as Topic; Europe; Flecainide; Heart Conduction System; Heart Failure; Humans; Multicenter Studies as Topic; Myocardial Infarction; Phenethylamines; Propafenone; Quinidine; Sotalol; Sulfonamides; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; United States	2003
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left	2003
[Atrial flutter and fibrillation]. Praxis, 2005, Nov-09, Volume: 94, Issue:45 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents	2005

Trials

15 trial(s) available for propafenone and quinidine

Article	Year
[Propafenon in ventricular arrhythmia caused by ischemic cardiopathy. Quantitative study using the Holter system]. Arquivos brasileiros de cardiologia, 1979, Volume: 33, Issue:4 Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Clinical Trials as Topic; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Perhexiline; Placebos; Propafenone; Propiophenones; Quinidine	1979
[Propafenone versus hydroquinidine in long-term pharmacological prophylaxis of atrial fibrillation]. Cardiologia (Rome, Italy), 1992, Volume: 37, Issue:2 Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Time Factors	1992
Propafenone versus quinidine slow-release for the treatment of chronic ventricular arrhythmias. Acta cardiologica, 1990, Volume: 45, Issue:5 Topics: Adult; Aged; Cardiac Complexes, Premature; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Ventricles; Humans; Male; Metabolic Clearance Rate; Middle Aged; Propafenone; Quinidine; Tachycardia	1990
Efficacy of propafenone compared with quinidine in chronic ventricular arrhythmias. The American journal of cardiology, 1985, Jun-01, Volume: 55, Issue:13 Pt 1 Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Humans; Male; Middle Aged; Propafenone; Propiophenones; Quinidine	1985
[Comparison of the efficacy of propafenone and hydroquinidine in stabilized extrasystolic ventricular arrhythmia by means of dynamic electrocardiographic Holter monitoring]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Electrocardiography; Female; Humans; Male; Middle Aged; Propafenone; Propiophenones; Quinidine	1984
Holter monitoring comparative assessment of propafenone and dihydroquinidine efficacy in the treatment of premature ventricular beats. Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:9 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Propafenone; Propiophenones; Quinidine; Time Factors	1983
Action of ATP on ventricular automaticity. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:5 Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Ajmaline; Animals; Anti-Arrhythmia Agents; Austria; Cardiac Pacing, Artificial; Drug Interactions; Emergency Medical Services; Female; Guinea Pigs; Heart Ventricles; Humans; Injections, Intravenous; Male; Propafenone; Prospective Studies; Quinidine; Tachycardia, Supraventricular; Ventricular Function; Verapamil	1994
Quinidine-enhanced beta-blockade during treatment with propafenone in extensive metabolizer human subjects. Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Synergism; Exercise; Female; Heart Rate; Humans; Isoproterenol; Male; Mixed Function Oxygenases; Phenotype; Propafenone; Quinidine; Stereoisomerism	1994
A controlled study on oral propafenone versus digoxin plus quinidine in converting recent onset atrial fibrillation to sinus rhythm. International journal of cardiology, 1994, Mar-01, Volume: 43, Issue:3 Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Combinations; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Propafenone; Quinidine; Remission Induction; Single-Blind Method; Ventricular Function	1994
[A comparison between propafenone and hydroquinidine perorally in the treatment of recent-onset atrial fibrillation]. Minerva cardioangiologica, 1996, Volume: 44, Issue:3 Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Evaluation; Female; Heart Rate; Humans; Male; Middle Aged; Propafenone; Quinidine; Time Factors	1996
Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial. Journal of internal medicine, 1996, Volume: 239, Issue:3 Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone; Quinidine; Recurrence; Time Factors	1996
Safety of oral propafenone in the conversion of recent onset atrial fibrillation to sinus rhythm: a prospective parallel placebo-controlled multicentre study. International journal of cardiology, 1999, Feb-28, Volume: 68, Issue:2 Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Digitalis Glycosides; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Safety; Treatment Outcome	1999
Control of paroxysmal atrial fibrillation recurrence using combined administration of propafenone and quinidine. The American journal of cardiology, 2000, Dec-15, Volume: 86, Issue:12 Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Recurrence; Safety; Treatment Outcome	2000
Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study. Cardiology journal, 2009, Volume: 16, Issue:6 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Digoxin; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Recurrence; Time Factors; Treatment Outcome	2009
Combined administration of quinidine and propafenone for atrial fibrillation: the CAQ-PAF study. Journal of clinical pharmacology, 2012, Volume: 52, Issue:2 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Heart Rate; Humans; Male; Middle Aged; Propafenone; Quinidine	2012

Other Studies

68 other study(ies) available for propafenone and quinidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis). Journal of medicinal chemistry, 2002, Dec-19, Volume: 45, Issue:26 Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase	2008
Determination of log D via automated microfluidic liquid-liquid extraction. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061 Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites	2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel. Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3 Topics: Animals; Anti-HIV Agents; Cell Line; Crystallography, X-Ray; Drug Discovery; ERG1 Potassium Channel; Female; Fluorine; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Microsomes, Liver; Molecular Structure; Protein Binding; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes	2020
Identification of C5-NH Journal of medicinal chemistry, 2021, 12-23, Volume: 64, Issue:24 Topics: Animals; Antiviral Agents; Biological Availability; Chick Embryo; Computer Simulation; Half-Life; Influenza A Virus, H5N1 Subtype; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Neuraminidase; Oseltamivir; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2021
[Anti-arrhythmia agents in heart failure]. Kardiologiia, 1992, Volume: 32, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Flecainide; Humans; Mexiletine; Middle Aged; Propafenone; Quinidine	1992
[Effects of propafenone, quinidine, and their combination on ventricular fibrillation threshold in dogs]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:4 Topics: Animals; Blood Pressure; Dogs; Drug Therapy, Combination; Female; Male; Propafenone; Quinidine; Ventricular Fibrillation	1992
Is pretransplant antiarrhythmic drug therapy a risk factor? Transplantation proceedings, 1992, Volume: 24, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Cause of Death; Child; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Mexiletine; Middle Aged; Postoperative Complications; Premedication; Propafenone; Quinidine; Sotalol; Survival Rate; Transplantation, Heterotopic	1992
Responsiveness of cardiac Na+ channels to antiarrhythmic drugs: the role of inactivation. The Journal of membrane biology, 1991, Volume: 122, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Dose-Response Relationship, Drug; Fluorides; Heart; Heart Rate; Lidocaine; Myocardium; Propafenone; Quinidine; Sodium Channels	1991
Myocardial uptake and pharmacodynamics of quinidine and propafenone in isolated rabbit hearts: metabolic versus respiratory acidosis. Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:4 Topics: Acidosis; Acidosis, Respiratory; Animals; Coronary Circulation; Electrocardiography; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardium; Propafenone; Quinidine; Rabbits	1991
Propafenone-induced torsade de pointes: cross-reactivity with quinidine. Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:11 Pt 1 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cross Reactions; Electrocardiography; Female; Humans; Propafenone; Quinidine; Torsades de Pointes	1991
New hope in atrial fibrillation. Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Propafenone; Quinidine; Sotalol	1990
Phasic ion channel blockade. A kinetic model and parameter estimation procedure. Molecular pharmacology, 1985, Volume: 28, Issue:4 Topics: Animals; Binding Sites; Biological Transport; Electric Stimulation; In Vitro Techniques; Ion Channels; Kinetics; Lidocaine; Membrane Potentials; Muscles; Propafenone; Propiophenones; Quinidine; Solubility; Stochastic Processes	1985
Genetically-determined interaction between propafenone and low dose quinidine: role of active metabolites in modulating net drug effect. British journal of clinical pharmacology, 1989, Volume: 27, Issue:4 Topics: Adult; Aged; Arrhythmias, Cardiac; Biotransformation; Electrocardiography; Female; Humans; Hydroxylation; Male; Middle Aged; Phenotype; Propafenone; Quinidine	1989
[Control of the efficacy of anti-arrhythmia drug therapy with the ambulatory electrocardiogram. Proposal for a new analytical statistical model]. Giornale italiano di cardiologia, 1985, Volume: 15, Issue:2 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Propafenone; Propiophenones; Prospective Studies; Quinidine; Retrospective Studies	1985
[Anti-arrhythmia efficacy of propafenone per os in the prevention of paroxysmal supraventricular arrhythmia resistant to class Ia agents]. Annales de cardiologie et d'angeiologie, 1989, Volume: 38, Issue:1 Topics: Administration, Oral; Aged; Disopyramide; Drug Evaluation; Drug Resistance; Female; Humans; Male; Middle Aged; Propafenone; Quinidine; Tachycardia, Paroxysmal; Tachycardia, Supraventricular	1989
Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs. Circulation research, 1988, Volume: 62, Issue:2 Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Dogs; Female; Heart Conduction System; Lidocaine; Male; Neural Conduction; Ouabain; Physical Exertion; Propafenone; Quinidine; Refractory Period, Electrophysiological; Sotalol	1988
Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine. American heart journal, 1987, Volume: 114, Issue:3 Topics: Adult; Aged; Anti-Arrhythmia Agents; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Stroke Volume	1987
[Method for differentiating in humans the direct effects of anti-arrhythmic drugs from those mediated by the autonomic nervous system. Effects of quinidine and propafenone]. Giornale italiano di cardiologia, 1986, Volume: 16, Issue:9 Topics: Adolescent; Adult; Aged; Atrioventricular Node; Autonomic Nervous System; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Propafenone; Quinidine; Sinoatrial Node	1986
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias. Japanese circulation journal, 1985, Volume: 49, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil	1985
Aggravation of ventricular arrhythmia. A drug-induced complication. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
[Anti-arrhythmia agents (I): Quinidine, procainamide, disopyramide, encainide, propafenone and flecainide]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
Use of short-term drug testing as part of a systematic approach for evaluation of antiarrhythmic drugs. Circulation, 1986, Volume: 73, Issue:2 Pt 2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Electric Stimulation; Humans; Monitoring, Physiologic; Procainamide; Prognosis; Propafenone; Propiophenones; Quinidine; Time Factors	1986
[Effects of anti-arrhythmia agents on heart rate. Significance and importance]. Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74 Spec No Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil	1981
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
[Combinations of some anti-arrhythmia drugs]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Humans; Mexiletine; Propafenone; Propiophenones; Quinidine	1984
European experience with the antiarrhythmic efficacy of propafenone for supraventricular and ventricular arrhythmias. The American journal of cardiology, 1984, Nov-14, Volume: 54, Issue:9 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Autonomic Nervous System; Cardiac Complexes, Premature; Child; Drug Therapy, Combination; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Propafenone; Propiophenones; Quinidine; Tachycardia; Wolff-Parkinson-White Syndrome	1984
The influence of some cardiodepressant drugs on the histamine-induced restoration of contractility in potassium-depolarized heart preparations. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 254, Issue:1 Topics: Animals; Calcium Channel Blockers; Depression, Chemical; Guinea Pigs; Histamine; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Potassium; Propafenone; Propiophenones; Quinidine; Thiopental	1981
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:12 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Recurrence; Retrospective Studies	1993
Chemically modified cardiac Na+ channels and their sensitivity to antiarrhythmics: is there a hidden drug receptor? The Journal of membrane biology, 1994, Volume: 139, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Cells, Cultured; Iodates; Lidocaine; Myocardium; Prajmaline; Propafenone; Quinidine; Rats; Receptors, Drug; Sodium Channels; Trypsin	1994
Voltage- and time-dependent inhibitory effects on rat aortic and porcine coronary artery contraction induced by propafenone and quinidine. British journal of pharmacology, 1994, Volume: 113, Issue:4 Topics: Animals; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Coronary Vessels; Electrophysiology; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Propafenone; Quinidine; Rats; Rats, Sprague-Dawley; Swine; Time Factors	1994
K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Electrophysiology; Flecainide; Heart; Heart Ventricles; Kinetics; Potassium Channels; Propafenone; Quinidine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity	1994
Antiarrhythmic drugs in the management of atrial fibrillation. British heart journal, 1993, Volume: 70, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Flecainide; Heart; Humans; Propafenone; Quinidine	1993
The metabolism of aprindine in relation to the sparteine/debrisoquine polymorphism. British journal of clinical pharmacology, 1993, Volume: 35, Issue:4 Topics: Aprindine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Polymorphism, Genetic; Propafenone; Quinidine; Sparteine	1993
Quinidine versus propafenone for conversion of atrial fibrillation to sinus rhythm. The American journal of cardiology, 1997, Aug-15, Volume: 80, Issue:4 Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Heart Rate; Humans; Male; Middle Aged; Propafenone; Quinidine; Treatment Outcome	1997
[Can 1/1 atrial flutter be foreseen by class I anti-arrhythmics?]. Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:7 Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Propafenone; Quinidine; Risk Factors	1997
[Pharmacological cardioversion of isolated atrial fibrillation: recovery of atrial mechanical function and correlation with duration of arrhythmia]. Giornale italiano di cardiologia, 1997, Volume: 27, Issue:10 Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Data Interpretation, Statistical; Echocardiography, Doppler, Pulsed; Female; Flecainide; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Propafenone; Quinidine; Recurrence; Time Factors	1997
Quinidine versus propafenone for conversion of atrial fibrillation to sinus rhythm. The American journal of cardiology, 1998, Feb-01, Volume: 81, Issue:3 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Rate; Humans; Propafenone; Quinidine; Treatment Outcome	1998
Hybrid pharmacologic and ablative therapy: a novel and effective approach for the management of atrial fibrillation. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone; Quinidine	1998
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle. European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2 Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; In Vitro Techniques; Methacholine Chloride; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium; Potassium Channels; Procainamide; Propafenone; Quinidine; Trachea	2000
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. British journal of pharmacology, 2002, Volume: 136, Issue:5 Topics: Cation Transport Proteins; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flecainide; Humans; Lidocaine; Neural Inhibition; Potassium Channels; Potassium Channels, Voltage-Gated; Propafenone; Quinidine; Trans-Activators; Transcriptional Regulator ERG	2002
A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30 Topics: Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Arachidonic Acid; Barium; Cell Line; Cloning, Molecular; Docosahexaenoic Acids; Electrophysiology; Ethanolamines; Fatty Acids; Fatty Acids, Nonesterified; Glyburide; Humans; Hydrogen-Ion Concentration; Lidocaine; Mice; Models, Biological; Molecular Sequence Data; Patch-Clamp Techniques; Phylogeny; Potassium Channels; Propafenone; Protein Structure, Tertiary; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Tissue Distribution; Transfection	2003
A comparison of some cardiac responses to Ro 2-5803 (Rythmol), quinidine and procaine amide in laboratory animals. Journal of the American Geriatrics Society, 1961, Volume: 9 Topics: Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Procainamide; Propafenone; Quinidine	1961
Atrial fibrillation: rate control often better than rhythm control. Prescrire international, 2004, Volume: 13, Issue:70 Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramide; Electric Countershock; Flecainide; Heart Rate; Humans; Netherlands; Platelet Aggregation Inhibitors; Propafenone; Quinidine; Sotalol; United States	2004
[Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium]. Orvosi hetilap, 2004, May-09, Volume: 145, Issue:19 Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiology Service, Hospital; Electric Countershock; Female; Follow-Up Studies; Hospital Departments; Humans; Hungary; Male; Middle Aged; Prajmaline; Propafenone; Quinidine; Retrospective Studies; Sotalol	2004
Limitations to antiarrhythmic drug use in patients with atrial fibrillation. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Sep-28, Volume: 171, Issue:7 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Contraindications; Female; Flecainide; Humans; Male; Middle Aged; Propafenone; Quinidine; Registries; Sotalol	2004
Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium. Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 371, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Chlorides; Colon, Descending; Electric Conductivity; Female; In Vitro Techniques; Intestinal Mucosa; Potassium; Potassium Channels, Calcium-Activated; Propafenone; Quinidine; Rabbits; Sodium	2005
Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:6 Topics: Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Genetic Techniques; Hepatocytes; Humans; Metoprolol; Microsomes, Liver; Polymorphism, Genetic; Propafenone; Propranolol; Quinidine	2005
Successful conversion of recent-onset atrial fibrillation by sequential administration of up to three antiarrhythmic drugs. Clinical cardiology, 2008, Volume: 31, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Administration Schedule; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Treatment Outcome; Young Adult	2008
Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation. Cardiology journal, 2009, Volume: 16, Issue:6 Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Heart Conduction System; Humans; Injections, Intravenous; Propafenone; Quinidine; Recurrence; Time Factors; Treatment Outcome	2009
In Silico Assessment of Class I Antiarrhythmic Drug Effects on International journal of molecular sciences, 2021, Jan-27, Volume: 22, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Computer Simulation; Disopyramide; Heart Atria; Homeobox Protein PITX2; Homeodomain Proteins; Humans; Mice; Propafenone; Quinidine; Transcription Factors	2021
Type 1 Brugada-Electrocardiogram: A Rare Presentation in a 57-Year-Old Woman with Paroxysmal Atrial Fibrillation Treated with a Therapeutic Dose of Propafenone. The Israel Medical Association journal : IMAJ, 2021, Volume: 23, Issue:7 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Clinical Decision-Making; Drug Substitution; Echocardiography; Electric Countershock; Female; Humans; Middle Aged; Propafenone; Quinidine; Treatment Outcome	2021