Page last updated: 2024-08-16

propafenone and mexiletine

propafenone has been researched along with mexiletine in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (50.00)	18.7374
1990's	15 (21.43)	18.2507
2000's	11 (15.71)	29.6817
2010's	9 (12.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Haruna, M; Kato, H; Lee, S; Machii, T; Nonokawa, M; Takanaka, C; Yabe, S	1
Cappiello, E; Dalla Vecchia, L; Lombardi, F; Sandrone, G; Torzillo, D	1
Kato, R; Koide, M; Miyahara, T; Sotobata, I; Toyama, J; Ukai, M; Yasui, S; Yokota, M	1
Delbressine, L; Harris, N; Kane, KA; Muir, AW; Winslow, E	1
Baĭer, T; Brakhmann, I; Khilbel, T; Kiubler, V; Shmitt, K; Valdeker, B	1
Deiwick, M; Konertz, W; Scheld, HH; Weyand, M	1
Boone, J; Kerr, CR; Murdock, CJ; Yeung-Lai-Wah, JA	1
Kokkas, B; Kotoula, M; Morali, A; Papadopoulos, K; Paradelis, A; Sphakianaki, E; Tsouderos, I	1
Cappiello, E; Castelli, A; Dalla Vecchia, L; Finocchiaro, ML; Lombardi, F; Pastine, J; Rech, R	1
Campbell, JK; Marshall, RJ; Winslow, E	1
Desai, DM; Gal, J; Meyer-Lehnert, S	1
Lampert, S; Lange, H; Lown, B; Sutton, MS	1
Brignole, M; Lolli, G; Menozzi, C; Monducci, I	1
Delpón, E; Tamargo, J; Valenzuela, C	1
Kates, RE; Liem, LB	1
Lampert, S; Lown, B; Podrid, PJ; Ravid, S	1
Aguglia, F; De Marzio, P; Gnecchi, M	1
Borodkin, VV; Dudaev, VA; Liusov, VA; Rudakov, AV	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Huang, SK; Marcus, FI	1
Garson, A; Moak, JP; Smith, RT	1
Bonazzi, O; Facchini, M; Priori, SG; Schwartz, PJ; Varisco, T	1
Lanza, GA; Lucente, M; Mondello Malvestiti, FM; Rebuzzi, AG; Tamburi, S	1
Amerini, S; Bernabei, R; Carbonin, P; Cerbai, E; Mugelli, A; Pahor, M	1
Sakai, K; Takagi, M; Yamazaki, T	1
Schwartz, PJ; Vanoli, E	1
Hirosawa, K; Kasanuki, H; Onishi, S	1
Podrid, PJ	2
Gang, ES; Hamer, A; Mandel, WJ; Oseran, DS; Peter, T; Rosenthal, ME	1
Sanna, GP	1
Schmitz, W	1
Somberg, JC	1
Ceci, V; Di Marcotullio, G; Dini, P; Milazzotto, F; Polizzi, C; Santini, M	1
Fabry, E; Klempt, HW; Nayebagha, A	1
Lüderitz, B	1
Rudolph, R; Seckfort, H; Seggewiss, H	1
Heger, JJ; Prystowsky, EN; Zipes, DP	1
Barbaresco, L; Bernasconi, M; Bossi, M; Brambilla, G; Marzegalli, M; Micheletti, T; Potenza, S; Regalia, F	1
Ambrosini, F; Finzi, A; Lo Masto, M; Lotto, A; Massari, FM; Pagnoni, F; Valentini, R	1
Angermann, C; Jahrmärker, H	1
Mouselimis, N; Wester, HA	1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P	1
Funke, H; Grube, E; Neumann, G	1
Bonatti, V; Botti, G; Disertori, M; Furlanello, F; Guarnerio, M; Inama, G; Rolli, A; Vergara, G	1
Böcker, K; Köhler, E; Loogen, F; Seipel, L	1
Broly, F; Caron, J; Lacroix, D; Lhermitte, M; Libersa, C	1
Agricola, E; Campolo, MA; D'Aprile, N; Faglia, S; Mangiacotti, L; Mondillo, S; Palazzuoli, V	1
Chiba, K; Ishizaki, T; Kobayashi, K; Kuroiwa, Y; Nakajima, M; Tani, M; Yamamoto, T	1
Ishii, K; Kubota, Y; Moriuchi, H; Nakahara, T; Sakamato, K; Shigenobu, K; Tanaka, Y; Yunoki, M	1
Adedoyin, A; Champagne, J; Gilbert, M; Hamelin, B; Labbé, L; Lefebvre, M; Lessard, E; O'Hara, G; Turgeon, J	1
Hennersdorf, MG; Niebch, V; Perings, C; Strauer, BE; Vester, EG; Winter, J	1
Eroğlu, S; Müderrisoğlu, H; Ozbiçer, S; Ozin, B	1
Becker, R; Katus, HA; Schmidt, C; Schweizer, PA; Thomas, D; Wiedmann, F	1
Carbonara, R; Conte Camerino, D; Costanza, T; Desaphy, JF	1
Johnson-Davis, KL; Slawson, MH	1

Reviews

9 review(s) available for propafenone and mexiletine

Article	Year
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Update: cardiac antiarrhythmic drugs. Comprehensive therapy, 1989, Volume: 15, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Propafenone; Propanolamines	1989
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)]. Klinische Wochenschrift, 1980, Sep-15, Volume: 58, Issue:18 Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide	1980
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol]. Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide	1982

Trials

6 trial(s) available for propafenone and mexiletine

Article	Year
Propafenone-mexiletine combination for the treatment of sustained ventricular tachycardia. Journal of the American College of Cardiology, 1992, Volume: 20, Issue:3 Topics: Adult; Aged; Drug Therapy, Combination; Electrocardiography; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propafenone; Tachycardia	1992
[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)]. Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:5 Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Coronary Disease; Electrocardiography; Flecainide; Half-Life; Heart Rate; Heart Ventricles; Humans; Mexiletine; Middle Aged; Myocardial Infarction; Piperidines; Propafenone; Propiophenones	1982
[Comparative evaluation of mexiletine and propafenone by dynamic electrocardiography]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Electrocardiography; Female; Humans; Male; Mexiletine; Middle Aged; Propafenone; Propiophenones; Propylamines	1984
[Comparative studies on the cardiodepressant effect of disopyramide, mexiletine and propafenon]. Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:11 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Male; Mexiletine; Myocardial Contraction; Propafenone; Propiophenones; Propylamines	1983
[The effect of anti-arrhythmic drugs on myocardial function (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1982, Aug-27, Volume: 107, Issue:34 Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Depression, Chemical; Disopyramide; Echocardiography; Humans; Lidocaine; Mexiletine; Middle Aged; Myocardial Contraction; Placebos; Propafenone; Propiophenones; Tocainide	1982
[Therapy of arrhythmia induced by myocardial ischemia. Association of L-carnitine, propafenone and mexiletine]. La Clinica terapeutica, 1995, Volume: 146, Issue:12 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Carnitine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Mexiletine; Middle Aged; Myocardial Ischemia; Propafenone; Ventricular Premature Complexes	1995

Other Studies

55 other study(ies) available for propafenone and mexiletine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Mexiletine and propafenone: a comparative study of monotherapy, low, and full dose combination therapy. Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2 Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Electrocardiography, Ambulatory; Female; Humans; Male; Mexiletine; Propafenone; Signal Processing, Computer-Assisted; Tachycardia, Ventricular	1992
Autonomic effects of antiarrhythmic drugs and their importance. European heart journal, 1992, Volume: 13 Suppl F Topics: Adult; Autonomic Nervous System; Cardiac Complexes, Premature; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Male; Mexiletine; Middle Aged; Propafenone; Tachycardia, Ventricular; Ventricular Fibrillation	1992
[Pharmacokinetics and pharmacodynamics of class I antiarrhythmic agents after a single oral administration]. Japanese circulation journal, 1992, Volume: 56 Suppl 5 Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Flecainide; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone	1992
Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12 Topics: Action Potentials; Administration, Oral; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Electrophysiology; Estrenes; Heart; Hemodynamics; Male; Mexiletine; Pentobarbital; Propafenone; Rats; Rats, Wistar	1992
[Anti-arrhythmia agents in heart failure]. Kardiologiia, 1992, Volume: 32, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Flecainide; Humans; Mexiletine; Middle Aged; Propafenone; Quinidine	1992
Is pretransplant antiarrhythmic drug therapy a risk factor? Transplantation proceedings, 1992, Volume: 24, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Cause of Death; Child; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Mexiletine; Middle Aged; Postoperative Complications; Premedication; Propafenone; Quinidine; Sotalol; Survival Rate; Transplantation, Heterotopic	1992
Interactions between digitoxin and some antiarrhythmic drugs. Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:5 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Digitoxin; Drug Interactions; Female; Male; Mexiletine; Propafenone; Rabbits; Radioimmunoassay	1992
Effects of mexiletine, propafenone and flecainide on signal-averaged electrocardiogram. European heart journal, 1992, Volume: 13, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Electrocardiography, Ambulatory; Female; Flecainide; Heart Diseases; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propafenone; Signal Processing, Computer-Assisted; Tachycardia	1992
Comparison of the electrophysiological effects of Org 7797, disopyramide, mexiletine and propafenone in anaesthetized dogs with myocardial infarcts. British journal of pharmacology, 1991, Volume: 104, Issue:2 Topics: Anesthetics; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dogs; Electrocardiography; Estrenes; Female; Male; Mexiletine; Myocardial Infarction; Propafenone; Ventricular Function	1991
Reversed-phase LC resolutions of chiral antiarrhythmic agents via derivatization with homochiral isothiocyanates. Chirality, 1990, Volume: 2, Issue:1 Topics: Anti-Arrhythmia Agents; Chromatography, Liquid; Flecainide; Humans; Indicators and Reagents; Lidocaine; Male; Mexiletine; Propafenone; Thiocyanates; Tocainide	1990
Changes in cardiac output determined by continuous-wave Doppler echocardiography during propafenone or mexiletine drug testing. The American journal of cardiology, 1990, Feb-15, Volume: 65, Issue:7 Topics: Cardiac Output; Depression, Chemical; Echocardiography, Doppler; Female; Heart Failure; Humans; Male; Mexiletine; Middle Aged; Propafenone; Stroke Volume; Tachycardia	1990
Noninvasive serial electrophysiological testing using an implanted pacemaker for management of recurrent ventricular tachycardia. Pacing and clinical electrophysiology : PACE, 1986, Volume: 9, Issue:4 Topics: Aged; Amiodarone; Electrophysiology; Heart Ventricles; Humans; Male; Mexiletine; Pacemaker, Artificial; Propafenone; Propiophenones; Recurrence; Sinoatrial Node; Tachycardia	1986
Electrophysiologic interactions between mexiletine and propafenone in guinea pig papillary muscles. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3 Topics: Action Potentials; Animals; Drug Interactions; Female; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Mexiletine; Papillary Muscles; Propafenone	1989
Congestive heart failure induced by six of the newer antiarrhythmic drugs. Journal of the American College of Cardiology, 1989, Nov-01, Volume: 14, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Female; Heart Failure; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Piperidines; Propafenone; Risk Factors; Stroke Volume; Tocainide	1989
Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report. International journal of cardiology, 1985, Volume: 7, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Heart Atria; Heart Ventricles; Hemodynamics; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Propylamines; Tachycardia	1985
[Changes in thrombocyte-vascular hemostasis and cyclic nucleotide levels after anti-arrhythmia therapy in patients with ischemic heart disease]. Kardiologiia, 1989, Volume: 29, Issue:1 Topics: Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Nucleotides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Propafenone	1989
Newer antiarrhythmic drugs in children. American heart journal, 1987, Volume: 113, Issue:1 Topics: Adolescent; Adult; Amiodarone; Anilides; Arrhythmias, Cardiac; Child; Child, Preschool; Electrocardiography; Encainide; Humans; Infant; Mexiletine; Moricizine; Phenothiazines; Propafenone	1987
Antiarrhythmic efficacy of penticainide and comparison with disopyramide, flecainide, propafenone and mexiletine by acute oral drug testing. The American journal of cardiology, 1987, Nov-01, Volume: 60, Issue:13 Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Disopyramide; Drug Administration Schedule; Electrocardiography; Electrophysiology; Female; Flecainide; Humans; Male; Mexiletine; Middle Aged; Propafenone; Propylamines; Pyridines	1987
[Worsening of ventricular arrhythmia in the dynamic ECG in patients treated with anti-arrhythmia drugs]. Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Monitoring, Physiologic; Propafenone	1988
Electrophysiological mechanism for the antiarrhythmic action of propafenone: a comparison with mexiletine. British journal of pharmacology, 1988, Volume: 95, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Mexiletine; Propafenone; Purkinje Fibers; Sheep	1988
Antiarrhythmic effects of a novel diamine derivative, AN-132, on several animal models of cardiac arrhythmias. The Tohoku journal of experimental medicine, 1987, Volume: 151, Issue:4 Topics: Aconitine; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Disopyramide; Dogs; Epinephrine; Ethylenediamines; Female; Guinea Pigs; Halothane; Male; Mexiletine; Ouabain; Propafenone; Rats; Rats, Inbred Strains	1987
An experimental approach to the choice of antiarrhythmic therapy. European heart journal, 1986, Volume: 7 Suppl A Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil	1986
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias. Japanese circulation journal, 1985, Volume: 49, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil	1985
Aggravation of ventricular arrhythmia. A drug-induced complication. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias. American heart journal, 1985, Volume: 110, Issue:5 Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; Female; Heart Arrest; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Mitral Valve Prolapse; Procainamide; Propafenone; Propiophenones; Propranolol; Risk	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
[Combinations of some anti-arrhythmia drugs]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Humans; Mexiletine; Propafenone; Propiophenones; Quinidine	1984
[Drug therapy of arrhythmia in coronary cardiopathy]. La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide	1983
[Esophageal ulcer caused by mexiletine]. Deutsche medizinische Wochenschrift (1946), 1983, Jul-01, Volume: 108, Issue:26 Topics: Aged; Cardiac Complexes, Premature; Esophageal Diseases; Female; Hemoptysis; Humans; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Propylamines; Ulcer	1983
Drug therapy of cardiac arrhythmias. Cardiology clinics, 1983, Volume: 1, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Biological Availability; Encainide; Half-Life; Humans; Imidazoles; Intestinal Absorption; Kinetics; Lidocaine; Metabolic Clearance Rate; Mexiletine; Propafenone; Propiophenones; Protein Binding; Tachycardia; Tocainide	1983
Hemodynamic effects of antiarrhythmic drugs in acute myocardial infarction. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Central Venous Pressure; Female; Heart Rate; Hemodynamics; Humans; Male; Mexiletine; Myocardial Infarction; Propafenone; Propiophenones; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance	1984
[The value of antitachycardia pacemaker therapy in patients with Wolff-Parkinson-White syndrome]. Herz, 1983, Volume: 8, Issue:3 Topics: Anti-Arrhythmia Agents; Bundle of His; Digitalis Glycosides; Disopyramide; Electrocardiography; Humans; Mexiletine; Pacemaker, Artificial; Propafenone; Propiophenones; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome	1983
[Validity and limits of invasive pharmacological tests in the treatment of malignant ventricular hyperkinetic arrhythmias]. Giornale italiano di cardiologia, 1983, Volume: 13, Issue:4 Topics: Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Female; Humans; Male; Mexiletine; Middle Aged; Propafenone; Propiophenones; Tachycardia	1983
[The effect of disopyramide, mexiletine and propafenon after intravenous and oral administration on left ventricular function in the M-mode echocardiogram]. Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:12 Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Therapy, Combination; Echocardiography; Female; Heart; Heart Ventricles; Humans; Injections, Intravenous; Male; Mexiletine; Propafenone; Propiophenones	1982
Interaction of propafenone and mexiletine. Journal of the American College of Cardiology, 1993, Volume: 22, Issue:7 Topics: Drug Interactions; Drug Therapy, Combination; Humans; Mexiletine; Propafenone; Tachycardia, Ventricular	1993
Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2. British journal of clinical pharmacology, 1998, Volume: 45, Issue:4 Topics: Anti-Arrhythmia Agents; Catalysis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Humans; Mexiletine; Microsomes, Liver; Propafenone	1998
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle. European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2 Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; In Vitro Techniques; Methacholine Chloride; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium; Potassium Channels; Procainamide; Propafenone; Quinidine; Trachea	2000
Pharmacokinetic and pharmacodynamic interaction between mexiletine and propafenone in human beings. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:1 Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Electrocardiography; Genotype; Humans; Male; Mexiletine; Mixed Function Oxygenases; Phenotype; Propafenone; Reference Values	2000
Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy. Cardiology, 2003, Volume: 99, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrophysiologic Techniques, Cardiac; Female; Follow-Up Studies; Heart Arrest; Humans; Male; Mexiletine; Middle Aged; Prognosis; Propafenone; Sotalol; Survivors; Time Factors; Treatment Outcome	2003
A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Defibrillators, Implantable; Electric Countershock; Electrocardiography; Female; Humans; Infusions, Intravenous; Mexiletine; Middle Aged; Myotonic Dystrophy; Propafenone; Tachycardia, Ventricular; Ultrasonography; Ventricular Dysfunction, Left	2009
Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels. European journal of pharmacology, 2013, Dec-05, Volume: 721, Issue:1-3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; CHO Cells; Cricetinae; Cricetulus; Humans; Mexiletine; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Tandem Pore Domain; Propafenone; Xenopus laevis	2013
Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs. Experimental neurology, 2014, Volume: 255 Topics: Animals; Carbamazepine; Disease Models, Animal; Flecainide; HEK293 Cells; Humans; Mexiletine; Muscle, Skeletal; Myotonia Congenita; Orphenadrine; Piperidines; Propafenone; Rats; Rats, Wistar; Riluzole; Sodium Channel Blockers; Thiazoles	2014
Quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1383 Topics: Amiodarone; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Flecainide; Humans; Mexiletine; Propafenone; Tandem Mass Spectrometry	2016