propafenone has been researched along with metoprolol in 46 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (8.70) | 18.7374 |
1990's | 9 (19.57) | 18.2507 |
2000's | 16 (34.78) | 29.6817 |
2010's | 16 (34.78) | 24.3611 |
2020's | 1 (2.17) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Pajeva, IK; Wiese, M | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Dalvie, D; Loi, CM; Smith, DA | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Herms, J; Kuck, KH; Schneider, M; Siebels, J | 1 |
Ahmad, S | 1 |
Korsukewitz, J; Schmutzler, H; Wegscheider, K | 1 |
Eichelbaum, M; Harnasch, P; Hauf, G; Jähnchen, E; Roskamm, H; Trenk, D; Wagner, F | 1 |
Jähnchen, E; Kalusche, D; Roskamm, H; Trenk, D; Wagner, F | 1 |
Delise, P; Di Pede, F; Piccolo, E; Raviele, A | 1 |
Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C | 1 |
Cappato, R; Kuck, KH; Rüppel, R; Schneider, MA; Siebels, J | 2 |
Kuck, KH; Siebels, J | 1 |
Kosmala, W | 1 |
Bjerregaard, P; Bleyer, FL; Caracciolo, EA; Quattromani, A | 1 |
Duan, Y; Gao, E; Li, H; Yang, C; Zhou, Y | 1 |
Bodor, E; Gellér, L; Matkó, I; Merkely, B; Moravcsik, E; Szabó, T; Szabolcs, Z; Turbók, E; Vágó, H | 1 |
Dorne, JL; Renwick, AG; Slob, W; Walton, K | 1 |
Ansink, JM; van Gelder, IC; van Veldhuisen, DJ; Wiesfeld, AC | 1 |
Iwaki, M; Komura, H | 1 |
Kohno, Y; Nagata, K; Suzuki, A; Yamamoto, T; Yamazoe, Y | 1 |
Kryński, T; Kułakowski, P; Sikorska, A; Stec, S; Szymot, J; Zaborska, B | 1 |
Pytkowski, M | 1 |
Marinescu, DC; Meltzer, V; Pincu, E | 1 |
Duricova, J; Grundmann, M; Jurckova, N; Kacirova, I; Perinova, I | 1 |
Ge, H; Jiang, H; Li, X; Liu, H | 1 |
Balik, M; Kolnikova, I; Kristof, J; Maly, M; Tavazzi, G; Waldauf, P | 1 |
Grundmann, M; Handlos, P; Kacirova, I; Kolek, M; Urinovska, R; Vyskocilova-Hrudikova, E | 1 |
Balik, M; Brestovansky, P; Brozek, T; Maly, M | 1 |
Azzam, ZS; Khoury, J | 1 |
Duan, H; Hua, Y; Li, Y; Lu, Y; Qiao, L; Wang, C; Yan, S; Zhou, K | 1 |
Duan, X; Gui, Y; Jia, J; Li, S; Liu, CC; Liu, G; Lu, Y; Zhang, M | 1 |
1 review(s) available for propafenone and metoprolol
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
7 trial(s) available for propafenone and metoprolol
Article | Year |
---|---|
[Prospective long-term ECG study of 100 patients surviving sudden cardiac death].
Topics: Adult; Aged; Amiodarone; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Rate; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Propafenone; Tachycardia, Ventricular | 1992 |
[Idiopathic ventricular tachyarrhythmia. Spontaneous variability and effect of various antiarrhythmic agents].
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propafenone; Propiophenones; Tachycardia | 1985 |
ICD versus drugs in cardiac arrest survivors: preliminary results of the Cardiac Arrest Study Hamburg.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; Follow-Up Studies; Germany; Heart Arrest; Humans; Incidence; Male; Metoprolol; Middle Aged; Propafenone; Prospective Studies; Recurrence; Survival Rate; Tachycardia, Ventricular; Ventricular Fibrillation | 1993 |
Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors (the Cardiac Arrest Study Hamburg).
Topics: Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; Heart Arrest; Humans; Incidence; Male; Metoprolol; Middle Aged; Propafenone; Prospective Studies; Risk Factors; Tachycardia, Ventricular; Ventricular Fibrillation | 1994 |
Preliminary results of the Cardiac Arrest Study Hamburg (CASH). CASH Investigators.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Propafenone; Prospective Studies; Regression Analysis; Tachycardia, Ventricular; Ventricular Fibrillation | 1993 |
Preliminary study of the effects of metoprolol and propafenone on ventricular arrhythmia with positive ventricular late potential.
Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Propafenone; Single-Blind Method; Tachycardia, Ventricular; Ventricular Premature Complexes | 1997 |
Benign symptomatic premature ventricular complexes: short- and long-term efficacy of antiarrhythmic drugs and radiofrequency ablation.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Catheter Ablation; Cross-Over Studies; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Propafenone; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; Ventricular Premature Complexes; Verapamil; Young Adult | 2012 |
38 other study(ies) available for propafenone and metoprolol
Article | Year |
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QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Metoprolol-induced delirium perpetuated by propafenone.
Topics: Adult; Delirium; Drug Interactions; Humans; Male; Metoprolol; Propafenone | 1991 |
Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.
Topics: Angina Pectoris; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Block; Hemodynamics; Humans; Inactivation, Metabolic; Male; Metabolic Clearance Rate; Metoprolol; Middle Aged; Phenotype; Propafenone; Sparteine | 1987 |
Drug interaction between propafenone and metoprolol.
Topics: Adult; Aged; Drug Interactions; Female; Half-Life; Heart Rate; Humans; Kinetics; Male; Metoprolol; Middle Aged; Physical Exertion; Propafenone | 1987 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propafenone; Propiophenones; Tachycardia; Ventricular Fibrillation | 1984 |
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect.
Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil | 1995 |
[The effect of treatment with propafenone, metoprolol and amiodarone on lymphocyte sodium efflux and level of cAMP in serum].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic AMP; Female; Heart Diseases; Humans; Lymphocytes; Male; Metoprolol; Middle Aged; Propafenone; Sodium | 1995 |
An aggressive approach in converting resistant atrial fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Electric Countershock; Electrocardiography; Humans; Male; Metoprolol; Propafenone; Retreatment; Treatment Failure | 1996 |
[Atrial fibrillation after open-heart surgery--incidence, prevention and treatment].
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Electric Countershock; Female; Humans; Incidence; Male; Metoprolol; Middle Aged; Propafenone; Retrospective Studies; Treatment Outcome | 2000 |
Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?
Topics: Adult; Aged; Aging; Benzhydryl Compounds; Cresols; Cyclohexanols; Cytochrome P-450 CYP2D6; Debrisoquin; Desipramine; Encainide; Ethnicity; Genetic Variation; Humans; Hydroxylation; Infant; Infant, Newborn; Kidney Diseases; Kinetics; Liver Diseases; Metabolic Clearance Rate; Metoprolol; Phenylpropanolamine; Polymorphism, Genetic; Propafenone; Substrate Specificity; Tolterodine Tartrate; Venlafaxine Hydrochloride | 2002 |
Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia?
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Therapy, Combination; Electrocardiography; Female; Humans; Metoprolol; Middle Aged; Propafenone; Tachycardia, Supraventricular | 2006 |
Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates.
Topics: Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Genetic Techniques; Hepatocytes; Humans; Metoprolol; Microsomes, Liver; Polymorphism, Genetic; Propafenone; Propranolol; Quinidine | 2005 |
Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Algorithms; Animals; Anisoles; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Area Under Curve; Baculoviridae; Desipramine; Drug Interactions; Humans; In Vitro Techniques; Insecta; Metoprolol; Microsomes; Microsomes, Liver; Models, Statistical; Propafenone; Propylamines; Thioridazine | 2006 |
[Not so simple procedure in "simple" arrhythmias of ventricular].
Topics: Anti-Arrhythmia Agents; Catheter Ablation; Female; Humans; Male; Metoprolol; Propafenone; Ventricular Premature Complexes; Verapamil | 2012 |
Thermodynamic study of binary system Propafenone Hydrocloride with Metoprolol Tartrate: solid-liquid equilibrium and compatibility with α-lactose monohydrate and corn starch.
Topics: Anti-Arrhythmia Agents; Calorimetry, Differential Scanning; Drug Compounding; Excipients; Lactose; Metoprolol; Models, Chemical; Phase Transition; Propafenone; Spectroscopy, Fourier Transform Infrared; Starch; Temperature; Thermodynamics; Zea mays | 2013 |
Clinically important interaction between metoprolol and propafenone.
Topics: Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Fibrillation; Cytochrome P-450 CYP2D6; Diuretics; Drug Interactions; Dyspnea; Fatigue; Female; Humans; Hypertension; Medication Reconciliation; Metoprolol; Propafenone | 2013 |
Predictors of Pharmacological Therapy of Ectopic Atrial Tachycardia in Children.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Child; Child, Preschool; China; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Logistic Models; Male; Metoprolol; Multivariate Analysis; Propafenone; Retrospective Studies; Sotalol; Tachycardia, Ectopic Atrial; Treatment Outcome | 2017 |
Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Critical Care; Electric Countershock; Female; Humans; Male; Metoprolol; Middle Aged; Propafenone; Retrospective Studies; Shock, Septic; Tachycardia, Supraventricular; Treatment Outcome | 2017 |
Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Anti-Arrhythmia Agents; Brain Edema; Cerebral Hemorrhage; Drug Interactions; Drug Overdose; Female; Heart Arrest; Humans; Metoprolol; Propafenone; Shock, Cardiogenic; Suicide | 2017 |
Reply.
Topics: Amiodarone; Arrhythmias, Cardiac; Humans; Metoprolol; Propafenone; Shock, Septic | 2018 |
Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Metoprolol; Propafenone; Shock, Septic | 2018 |
A delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia with a mutant of RYR2 at c.7580T>G for 6 years in a 9-year-old child.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Death, Sudden, Cardiac; Delayed Diagnosis; Electrocardiography; Exercise Test; Genetic Testing; Humans; Male; Metoprolol; Mutation; Physical Exertion; Propafenone; Ryanodine Receptor Calcium Release Channel; Syncope; Tachycardia, Ventricular | 2018 |
Direct analysis in real time-mass spectrometry for rapid quantification of five anti-arrhythmic drugs in human serum: application to therapeutic drug monitoring.
Topics: Amiodarone; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Computer Systems; Diltiazem; Drug Monitoring; Humans; Metoprolol; Pharmaceutical Preparations; Propafenone; Tandem Mass Spectrometry; Verapamil | 2020 |