Page last updated: 2024-08-16

propafenone and lidocaine

propafenone has been researched along with lidocaine in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	36 (48.65)	18.7374
1990's	18 (24.32)	18.2507
2000's	12 (16.22)	29.6817
2010's	7 (9.46)	24.3611
2020's	1 (1.35)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kato, R; Koide, M; Miyahara, T; Sotobata, I; Toyama, J; Ukai, M; Yasui, S; Yokota, M	1
Rabkin, SW	1
Benz, I; Kohlhardt, M	2
Magnani, A; Occhetta, E; Perucca, A; Piccinino, C; Rognoni, G; Rossi, P	1
Desai, DM; Gal, J; Meyer-Lehnert, S	1
Grant, AO; Starmer, CF	1
Hashimoto, K; Ishii, M; Komori, S; Mitsuhashi, H	1
Bell, P; Martorana, M; Winslow, E	1
Lampert, S; Lown, B; Podrid, PJ; Ravid, S	1
Hoffman, BF; Spinelli, W	1
Fichtner, H; Fröbe, U; Herzig, JW; Kohlhardt, M	1
Aguglia, F; De Marzio, P; Gnecchi, M	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Huang, SK; Marcus, FI	1
Agarwal, JB; Ambrosioni, E; Bracchetti, D; Helfant, RH; Naccarella, F; Weintraub, WS	1
Puddu, PE; Rouet, R	1
Atallah, G; Ferry, S; Kirkorian, G; Marchand, A; Mathieu, MP; Moleur, P; Stahl, C; Touboul, P; Vrancea, F; Zoheir, F	1
Allessie, MA; Bonke, FI; Lammers, WJ; Rensma, PL; Schalij, MJ	1
Feld, GK; Kirsten, E; Nademanee, K; Singh, BN	1
Schwartz, PJ; Vanoli, E	1
Hirosawa, K; Kasanuki, H; Onishi, S	1
Podrid, PJ	1
Sanna, GP	1
Schmitz, W	1
Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P	1
Somberg, JC	1
Himmler, C; Klein, G; Neiss, A; Schlegl, J; Wirtzfeld, A	1
Lüderitz, B	1
Ericsson, CG; Eriksson, S; Olsson, G; Rehnqvist, N; Svensson, G	1
Gebhardt, A; Hilpert, P; Schmuderer, R	1
Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Gramegna, L; Inama, G; Vergara, G	1
Heger, JJ; Prystowsky, EN; Zipes, DP	1
Agarwal, JB; Bracchetti, D; Helfant, RH; Naccarella, FF; Weintraub, WS	1
Karagueuzian, HS; Katoh, T; Mandel, WJ; McCullen, A; Peter, T	1
Bernardes, Rde C; Borges, MZ; de Almeida, RC; de Souza, LS; Marino, MA; Marino, RL; Rabelo, RC; Rabelo, W; Serufo, JC	1
Mouselimis, N; Wester, HA	1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P	1
Fujimoto, T; Karagueuzian, HS; Katoh, T; Mandel, WJ; McCullen, A; Peter, T	1
Glogar, D; Laimer, H; Zilcher, H	1
Ledda, F; Mantelli, L; Manzini, S; Mugelli, A	1
Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C	1
Beleslin, BB; Dekleva, MN	1
Campbell, TJ; Wyse, KR; Ye, VZ	1
Liu, L; Tang, YN; Wang, ZY; Zhang, WL	1
Gutiérrez-Larraya, F; Jabón, A	1
Bellone, P; Spirito, P; Vecchio, C	1
Higuchi, M; Itomine, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N	1
Cronenberger, CL; Griffith, RK; Lalka, D	1
Chow, MS; Fan, C; Kluger, J; O'Rangers, EA; Pharand, C; Ujhelyi, MR	1
Akaike, N; Inomata, N; Ishihara, T; Ohno, T	1
Decrinis, M; Kasper, K; Pilger, E; Schwarzl, I; Stark, G; Stark, U; Tritthart, HA	1
Iwasa, A; Matsunaga, T; Okumura, K; Tabuchi, T; Tayama, S; Tsuchiya, T; Tsunoda, R; Yasue, H	1
Hancox, JC; Paul, AA; Witchel, HJ	1
Furuichi, K; Inamura, K; Kitada, C; Matsushime, H; Miyake, A; Mochizuki, S; Nozawa, K; Okada, H; Sano, Y; Yokoi, H	1
Fujimura, A; Sakamoto, K; Shiga, T; Tsuruoka, S; Wakaumi, M	1
Antzelevitch, C; Belardinelli, L; Burashnikov, A; Di Diego, JM; Zygmunt, AC	1
Faggioni, M; Hasdemir, C; Hwang, HS; Knollmann, BC; Laver, D; Mehra, D; Turhan, K; Yin, H	1
Cupić, V; Gojković-Bukarica, L; Heinle, H; Ivković, B; Novaković, R; Vladimirov, S	1
Deguchi, N; Hamaguchi, S; Hashimoto, T; Hiiro, H; Kaneko, M; Mizoguchi, M; Namekata, I; Takahashi, Y; Tanaka, H	1

Reviews

10 review(s) available for propafenone and lidocaine

Article	Year
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)]. Klinische Wochenschrift, 1980, Sep-15, Volume: 58, Issue:18 Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide	1980
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol]. Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide	1982
[Tachycardias: considerations in childhood in the 90s]. Anales espanoles de pediatria, 1993, Volume: 39, Issue:6 Topics: Adenosine; Adolescent; Adult; Amiodarone; Atrial Flutter; Child; Child, Preschool; Electrocardiography; Ergometry; Flecainide; Heart; Heart Ventricles; Humans; Infant; Infant, Newborn; Lidocaine; Middle Aged; Propafenone; Sotalol; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Tachycardia, Ventricular	1993
The hepatic first-pass metabolism of problematic drugs. Journal of clinical pharmacology, 1993, Volume: 33, Issue:7 Topics: Animals; Anti-Arrhythmia Agents; Humans; Lidocaine; Liver; Metabolic Clearance Rate; Models, Biological; Nitroglycerin; Pharmaceutical Preparations; Propafenone; Propranolol; Verapamil	1993

Trials

6 trial(s) available for propafenone and lidocaine

Article	Year
A comparative evaluation of the effects of propafenone and lidocaine on early ventricular arrhythmias after acute myocardial infarction. European heart journal, 1988, Volume: 9, Issue:11 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Female; Heart Rupture, Post-Infarction; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Propafenone; Random Allocation; Time Factors	1988
[Efficacy of anti-arrhythmia agents]. Medizinische Klinik, 1980, Nov-21, Volume: 75, Issue:24 Topics: Adult; Aged; Ajmaline; Androstanols; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Placebos; Propafenone; Propiophenones	1980
Comparative investigation of the antiarrhythmic effect of propafenone (Rytmonorm) and lidocaine in patients with ventricular arrhythmias during acute myocardial infarction. Acta medica Scandinavica, 1984, Volume: 216, Issue:5 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Heart Rate; Heart Ventricles; Humans; Lidocaine; Myocardial Infarction; Propafenone; Propiophenones	1984
[Comparative studies of tocainide and propafenone in the treatment of ventricular arrhythmias]. Arzneimittel-Forschung, 1984, Volume: 34, Issue:3 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Propafenone; Propiophenones; Tocainide	1984
[Ventricular tachycardia--Effects of propafenon by intravenous route. Comparative study with lidocaine]. Arquivos brasileiros de cardiologia, 1981, Volume: 37, Issue:1 Topics: Adult; Aged; Clinical Trials as Topic; Electrocardiography; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Propafenone; Propiophenones; Tachycardia	1981
[The effect of anti-arrhythmic drugs on myocardial function (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1982, Aug-27, Volume: 107, Issue:34 Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Depression, Chemical; Disopyramide; Echocardiography; Humans; Lidocaine; Mexiletine; Middle Aged; Myocardial Contraction; Placebos; Propafenone; Propiophenones; Tocainide	1982

Other Studies

58 other study(ies) available for propafenone and lidocaine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
[Pharmacokinetics and pharmacodynamics of class I antiarrhythmic agents after a single oral administration]. Japanese circulation journal, 1992, Volume: 56 Suppl 5 Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Flecainide; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone	1992
Effect of antiarrhythmic drugs on choline uptake in cardiac cells in culture. Cardiovascular research, 1992, Volume: 26, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Chick Embryo; Choline; Dose-Response Relationship, Drug; Encainide; Flecainide; Heart; Lidocaine; Myocardium; Propafenone; Tocainide	1992
Responsiveness of cardiac Na+ channels to antiarrhythmic drugs: the role of inactivation. The Journal of membrane biology, 1991, Volume: 122, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Dose-Response Relationship, Drug; Fluorides; Heart; Heart Rate; Lidocaine; Myocardium; Propafenone; Quinidine; Sodium Channels	1991
[Termination of ventricular tachycardia by noninvasive methods]. Minerva cardioangiologica, 1991, Volume: 39, Issue:6 Topics: Cardiac Pacing, Artificial; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Propafenone; Tachycardia	1991
Reversed-phase LC resolutions of chiral antiarrhythmic agents via derivatization with homochiral isothiocyanates. Chirality, 1990, Volume: 2, Issue:1 Topics: Anti-Arrhythmia Agents; Chromatography, Liquid; Flecainide; Humans; Indicators and Reagents; Lidocaine; Male; Mexiletine; Propafenone; Thiocyanates; Tocainide	1990
Phasic ion channel blockade. A kinetic model and parameter estimation procedure. Molecular pharmacology, 1985, Volume: 28, Issue:4 Topics: Animals; Binding Sites; Biological Transport; Electric Stimulation; In Vitro Techniques; Ion Channels; Kinetics; Lidocaine; Membrane Potentials; Muscles; Propafenone; Propiophenones; Quinidine; Solubility; Stochastic Processes	1985
Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: a comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone, tocainide, and SUN 1165. Heart and vessels, 1985, Volume: 1, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Epinephrine; Female; Ion Channels; Lidocaine; Ligation; Male; Ouabain; Propafenone; Propiophenones; Sodium; Tocainide	1985
Electrophysiologic effects of Org 7797, a new steroidal antiarrhythmic agent: comparison with class 1a, 1b, and 1c drugs. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Estrenes; Female; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Propafenone; Purkinje Fibers; Sodium Channels; Swine	1989
Congestive heart failure induced by six of the newer antiarrhythmic drugs. Journal of the American College of Cardiology, 1989, Nov-01, Volume: 14, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Female; Heart Failure; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Piperidines; Propafenone; Risk Factors; Stroke Volume; Tocainide	1989
Mechanisms of termination of reentrant atrial arrhythmias by class I and class III antiarrhythmic agents. Circulation research, 1989, Volume: 65, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Lidocaine; Piperidines; Propafenone; Sotalol	1989
On the mechanism of drug-induced blockade of Na+ currents: interaction of antiarrhythmic compounds with DPI-modified single cardiac Na+ channels. Circulation research, 1989, Volume: 64, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Cells, Cultured; Imidazolines; Lidocaine; Myocardium; Prajmaline; Propafenone; Rats; Sodium; Sodium Channels	1989
Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report. International journal of cardiology, 1985, Volume: 7, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Heart Atria; Heart Ventricles; Hemodynamics; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Propylamines; Tachycardia	1985
[Myocardial distribution of C-14 lidocaine and C-14 propafenone in relation to regional myocardial blood flow in a model of chronic-phase myocardial infarct]. Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:5 Topics: Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Lidocaine; Microspheres; Myocardial Infarction; Myocardium; Propafenone	1988
Are different pharmacokinetic properties of lidocaine versus propafenone in normal as compared to ischemic myocardium responsible for different electrophysiologic effects which help preventing arrhythmias? Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:5 Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Electrophysiology; Guinea Pigs; In Vitro Techniques; Lidocaine; Myocardial Infarction; Myocardium; Propafenone	1988
Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs. Circulation research, 1988, Volume: 62, Issue:2 Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Dogs; Female; Heart Conduction System; Lidocaine; Male; Neural Conduction; Ouabain; Physical Exertion; Propafenone; Quinidine; Refractory Period, Electrophysiological; Sotalol	1988
Hemodynamic and electrophysiologic effects of combined infusion of lidocaine and propafenone in humans. Journal of clinical pharmacology, 1987, Volume: 27, Issue:1 Topics: Adult; Aged; Arrhythmias, Cardiac; Electrophysiology; Female; Hemodynamics; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Propafenone	1987
An experimental approach to the choice of antiarrhythmic therapy. European heart journal, 1986, Volume: 7 Suppl A Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil	1986
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias. Japanese circulation journal, 1985, Volume: 49, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
[Effects of anti-arrhythmia agents on heart rate. Significance and importance]. Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74 Spec No Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil	1981
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
[Drug therapy of arrhythmia in coronary cardiopathy]. La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide	1983
Worsening of arrhythmias during pharmacological treatment. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Adolescent; Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Child; Disopyramide; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Nadolol; Piperidines; Propafenone; Propanolamines; Propiophenones; Tocainide	1984
Drug therapy of cardiac arrhythmias. Cardiology clinics, 1983, Volume: 1, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Biological Availability; Encainide; Half-Life; Humans; Imidazoles; Intestinal Absorption; Kinetics; Lidocaine; Metabolic Clearance Rate; Mexiletine; Propafenone; Propiophenones; Protein Binding; Tachycardia; Tocainide	1983
Epicardial, endocardial and transmural mapping in assessing electrophysiological effects of 14-C lidocaine and 14-C propafenone on activation times in experimental chronic myocardial infarction. Correlations with myocardial drugs concentrations. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Radioisotopes; Coronary Circulation; Dogs; Electrophysiology; Endocardium; Heart Ventricles; Lidocaine; Myocardial Infarction; Myocardium; Propafenone; Propiophenones; Tachycardia; Ventricular Fibrillation	1984
Electrophysiologic and hemodynamic effects of propafenone, a new antiarrhythmic agent, on the anesthetized, closed-chest dog: comparative study with lidocaine. American heart journal, 1984, Volume: 107, Issue:3 Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Heart Rate; Hemodynamics; Lidocaine; Male; Propafenone; Propiophenones	1984
Suppression of ventricular arrhythmias by propafenone, a new antiarrhythmic agent, during acute myocardial infarction in the conscious dog. A comparative study with lidocaine. Circulation, 1982, Volume: 66, Issue:6 Topics: Animals; Arterial Occlusive Diseases; Coronary Disease; Depression, Chemical; Diastole; Dogs; Electrocardiography; Female; Injections, Intravenous; Lidocaine; Male; Myocardial Infarction; Propafenone; Propiophenones; Sinoatrial Node; Tachycardia	1982
[Therapy of ventricular tachyarrhythmias refractory to lidocaine with propafenone (author's transl)]. Acta medica Austriaca, 1981, Volume: 8, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Drug Evaluation; Drug Resistance; Female; Heart Ventricles; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Propafenone; Propiophenones; Tachycardia; Ventricular Fibrillation	1981
The influence of some cardiodepressant drugs on the histamine-induced restoration of contractility in potassium-depolarized heart preparations. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 254, Issue:1 Topics: Animals; Calcium Channel Blockers; Depression, Chemical; Guinea Pigs; Histamine; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Potassium; Propafenone; Propiophenones; Quinidine; Thiopental	1981
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil	1995
Neurotoxic action of some antiarrhythmic agents: comparative effects of propafenone, lidocaine and amiodarone on leech Retzius nerve cell. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 110, Issue:2 Topics: Action Potentials; Amiodarone; Animals; Calcium; Ganglia, Invertebrate; Leeches; Lidocaine; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channels; Propafenone	1995
Lidocaine shows greater selective depression of depolarized and acidotic myocardium than propafenone: possible implications for proarrhythmia. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1 Topics: Action Potentials; Analysis of Variance; Animals; Arrhythmias, Cardiac; Female; Guinea Pigs; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Microelectrodes; Myocardial Ischemia; Potassium; Propafenone	1993
[Metabolism of propafenone and lidocaine in combination in rat liver supernatant]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:6 Topics: Animals; Drug Synergism; Lidocaine; Liver; Male; Propafenone; Rats; Rats, Wistar	1994
Chemically modified cardiac Na+ channels and their sensitivity to antiarrhythmics: is there a hidden drug receptor? The Journal of membrane biology, 1994, Volume: 139, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Cells, Cultured; Iodates; Lidocaine; Myocardium; Prajmaline; Propafenone; Quinidine; Rats; Receptors, Drug; Sodium Channels; Trypsin	1994
Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone. International journal of cardiology, 1994, Mar-01, Volume: 43, Issue:3 Topics: Amiodarone; Electric Countershock; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Myocardial Infarction; Propafenone; Recurrence; Time Factors; Ventricular Fibrillation	1994
Effects of pilsicainide on systemic hemodynamics and cardiac function of anesthetized dogs. Cardioscience, 1993, Volume: 4, Issue:4 Topics: Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Dogs; Female; Flecainide; Heart; Hemodynamics; Lidocaine; Male; Myocardial Contraction; Propafenone	1993
The pharmacokinetic and pharmacodynamic interaction between propafenone and lidocaine. Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:1 Topics: Adult; Blood Pressure; Drug Interactions; Electrocardiography; Humans; Infusions, Intravenous; Lidocaine; Male; Phenotype; Propafenone; Random Allocation; Regression Analysis	1993
Antiarrhythmic agents act differently on the activation phase of the ACh-response in guinea-pig atrial myocytes. British journal of pharmacology, 1993, Volume: 108, Issue:1 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Conductivity; Flecainide; Guinea Pigs; Lidocaine; Male; Myocardium; Potassium; Potassium Channels; Propafenone	1993
Influence of duration of rapid ventricular pacing on ventricular refractoriness in the presence of propafenone and lidocaine. Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:1 Pt 1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bundle of His; Cardiac Pacing, Artificial; Electric Stimulation; Electrocardiography; Female; Guinea Pigs; Heart Conduction System; Heart Rate; Heart Ventricles; Lidocaine; Male; Neural Conduction; Propafenone; Refractory Period, Electrophysiological; Regression Analysis; Sodium Channels; Time Factors	1997
Effects of pilsicainide and propafenone on vagally induced atrial fibrillation: role of suppressant effect in conductivity. European journal of pharmacology, 1998, Aug-28, Volume: 356, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Output; Dogs; Electric Conductivity; Electric Stimulation; Electrophysiology; Female; Heart Atria; Heart Rate; Humans; Lidocaine; Male; Propafenone; Vagus Nerve	1998
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. British journal of pharmacology, 2002, Volume: 136, Issue:5 Topics: Cation Transport Proteins; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flecainide; Humans; Lidocaine; Neural Inhibition; Potassium Channels; Potassium Channels, Voltage-Gated; Propafenone; Quinidine; Trans-Activators; Transcriptional Regulator ERG	2002
A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30 Topics: Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Arachidonic Acid; Barium; Cell Line; Cloning, Molecular; Docosahexaenoic Acids; Electrophysiology; Ethanolamines; Fatty Acids; Fatty Acids, Nonesterified; Glyburide; Humans; Hydrogen-Ion Concentration; Lidocaine; Mice; Models, Biological; Molecular Sequence Data; Patch-Clamp Techniques; Phylogeny; Potassium Channels; Propafenone; Protein Structure, Tertiary; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Tissue Distribution; Transfection	2003
Pilsicainide in breast milk from a mother: comparison with disopyramide and propafenone. British journal of clinical pharmacology, 2005, Volume: 59, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Disopyramide; Female; Humans; Lidocaine; Milk, Human; Propafenone	2005
Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation. Annals of the New York Academy of Sciences, 2008, Volume: 1123 Topics: Acetanilides; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Dogs; Electrophysiology; Heart Atria; Humans; Lidocaine; Piperazines; Propafenone; Ranolazine; Sodium Channel Blockers; Ventricular Function	2008
Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia. Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:2 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calsequestrin; Defibrillators, Implantable; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Flecainide; Humans; Ion Channel Gating; Lidocaine; Male; Mice; Mice, Knockout; Mutation, Missense; Myocytes, Cardiac; Procainamide; Propafenone; Ryanodine Receptor Calcium Release Channel; Sodium Channel Blockers; Tachycardia, Ventricular; Time Factors; Young Adult	2011
The novel phenylpropiophenone derivates induced relaxation of isolated rat aorta. Arzneimittel-Forschung, 2012, Volume: 62, Issue:7 Topics: Animals; Aorta; In Vitro Techniques; Lidocaine; Male; Nifedipine; Phenylephrine; Propafenone; Propiophenones; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilation	2012
Negative Inotropic Effects of Class I Antiarrhythmics on Guinea Pig Ventricular Myocardium: Correlation with L-Type Ca Biological & pharmaceutical bulletin, 2023, Volume: 46, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Guinea Pigs; Lidocaine; Myocardium; Papillary Muscles; Propafenone	2023