Page last updated: 2024-08-16

propafenone and isoproterenol

propafenone has been researched along with isoproterenol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's5 (26.32)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cokkinos, DV; Katsaros, C; Manolis, AS1
Fromer, M; Goy, JJ; Kappenberger, L; Schlaepfer, J1
Cantor, E; Greenberg, S; Paul, J1
Jähnchen, E; Trenk, D; Wagner, F1
Campa, MA; Dubuc, M; Kus, T; Lambert, C; Rosengarten, M; Shenasa, M1
Campbell, JK; Logan, RT; Marshall, RJ; McGarry, G; Sleigh, T; Winslow, E1
Bolognesi, R; Manca, C; Poli, E; Raddino, R; Visioli, O1
Delgado, C; Tamargo, J; Tejerina, T1
Gries, J; Hofmann, HP; Kreiskott, H; Kretzschmar, R; Müller, CD; Raschack, M; Teschendorf, HJ; von Philipsborn, G1
Belardinelli, L; Lucchese, FA; Sant'Anna, JR1
Mörike, KE; Roden, DM1
Csöllei, J; Ecker, G; Otrusník, R; Racanská, E; Svec, P; Tumová, I1
Biffi, M; Boriani, G; Branzi, A; Bronzetti, G; Capucci, A; Magnani, B1
Kirstein, M; Maier, SK1

Reviews

1 review(s) available for propafenone and isoproterenol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for propafenone and isoproterenol

ArticleYear
Evaluation of the beta-adrenoceptor blocking activity of the Class Ic antiarrhythmic drug diprafenone in man.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Isoproterenol; Male; Propafenone; Propranolol; Random Allocation

1989
Electrophysiologic effects of intravenous propafenone in Wolff-Parkinson-White syndrome.
    American heart journal, 1989, Volume: 117, Issue:2

    Topics: Adult; Cardiac Pacing, Artificial; Clinical Trials as Topic; Double-Blind Method; Electrophysiology; Humans; Infant, Newborn; Injections, Intravenous; Isoproterenol; Middle Aged; Propafenone; Refractory Period, Electrophysiological; Tachycardia; Wolff-Parkinson-White Syndrome

1989
Quinidine-enhanced beta-blockade during treatment with propafenone in extensive metabolizer human subjects.
    Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Synergism; Exercise; Female; Heart Rate; Humans; Isoproterenol; Male; Mixed Function Oxygenases; Phenotype; Propafenone; Quinidine; Stereoisomerism

1994

Other Studies

15 other study(ies) available for propafenone and isoproterenol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Electrophysiological and electropharmacological studies in pre-excitation syndromes: results with propafenone therapy and isoproterenol infusion testing.
    European heart journal, 1992, Volume: 13, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Cardiac Pacing, Artificial; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoproterenol; Male; Pre-Excitation Syndromes; Propafenone; Prospective Studies; Time Factors; Wolff-Parkinson-White Syndrome

1992
Electrophysiologic effects of intravenous propafenone at rest, during isoproterenol infusion and during exercise in the Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1991, Sep-01, Volume: 68, Issue:6

    Topics: Adolescent; Adult; Atrioventricular Node; Cardiac Catheterization; Electrocardiography; Electrophysiology; Heart Rate; Humans; Infusions, Intravenous; Isoproterenol; Male; Middle Aged; Physical Exertion; Propafenone; Refractory Period, Electrophysiological; Rest; Tachycardia; Wolff-Parkinson-White Syndrome

1991
Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Dihydroalprenolol; Dogs; Female; Heart; Isoproterenol; Male; Membranes; Myocardium; Propafenone; Propranolol; Receptors, Adrenergic, beta

1989
Antiarrhythmic activity of 17 beta-aminoestratrienes. Comparison of 3-ols and 3-acetates with the corresponding 3-(3-amino-2-hydroxypropyl) ethers.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Estrenes; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Mice; Practolol; Propafenone; Propiophenones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Structure-Activity Relationship

1986
Effects of 17 beta-estradiol on the isolated rabbit heart.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 281, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vasospasm; Depression, Chemical; Estradiol; Female; Heart; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitroglycerin; Propafenone; Propiophenones; Propranolol; Rabbits; Vascular Resistance; Vasopressins

1986
Electrophysiological effects of propafenone in untreated and propafenone-pretreated guinea-pig atrial and ventricular muscle fibres.
    British journal of pharmacology, 1985, Volume: 86, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Caffeine; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Heart Conduction System; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Papillary Muscles; Propafenone; Propiophenones; Sinoatrial Node

1985
Pharmacological studies on propafenone and its main metabolite 5-hydroxypropafenone.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:11

    Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Calcium Channel Blockers; Dogs; Electrocardiography; Electroencephalography; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Infarction; Propafenone; Propiophenones; Rabbits; Rats; Rats, Inbred Strains; Tachycardia

1984
[Effect of propafenon on sinus node function].
    Arquivos brasileiros de cardiologia, 1980, Volume: 35, Issue:1

    Topics: Animals; Depression, Chemical; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male; Propafenone; Propiophenones; Sinoatrial Node

1980
[Pharmaco-toxicologic evaluation of newly synthesized analogs of propafenone].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 1997, Volume: 46, Issue:3

    Topics: Adrenergic beta-Agonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Guinea Pigs; Isoproterenol; Propafenone

1997
Electrophysiological effects of flecainide and propafenone on atrial fibrillation cycle and relation with arrhythmia termination.
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Humans; Isoproterenol; Male; Middle Aged; Propafenone; Prospective Studies; Signal Processing, Computer-Assisted; Stimulation, Chemical

1999
Beta-adrenergic stimulation modulates the sodium current block by propafenone in rat ventricular myocardium.
    Journal of electrocardiology, 2002, Volume: 35, Issue:4

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atenolol; Electrophysiologic Techniques, Cardiac; Female; Heart Ventricles; Isoproterenol; Models, Animal; Models, Cardiovascular; Myocardium; Propafenone; Rats; Rats, Wistar; Sodium Channels; Stimulation, Chemical

2002