propafenone has been researched along with diprafenone in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (46.88) | 18.7374 |
| 1990's | 15 (46.88) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Honjo, H; Kodama, I; Suzuki, R; Toyama, J | 1 |
| Groschner, K; Kukovetz, WR; Lindner, W; Schnedl, H | 1 |
| Wunderlich, E | 1 |
| Frohner, K; Hief, C; Kaltenbrunner, W; Nürnberg, M; Podczeck, A; Steinbach, K | 1 |
| Nanoff, C; Schütz, W | 1 |
| Blaschke, G; Hollenhorst, T | 1 |
| Austin, D; Espinosa-Crouch, G; Koziol, T; Woolf, E | 1 |
| Fichtner, H; Kohlhardt, M | 2 |
| Geibel, A; Hohnloser, S; Just, H; Landsrath, C; Meinertz, T; Zehender, M | 1 |
| Cantor, E; Greenberg, S; Paul, J | 1 |
| Geiger, M; Kuck, KH; Kunze, KP; Schlüter, M | 1 |
| Kramer, W; Kremer, P; Schlepper, M; Thormann, J | 1 |
| Fichtner, H; Fröbe, U; Herzig, JW; Kohlhardt, M | 1 |
| Jähnchen, E; Trenk, D; Wagner, F | 1 |
| Jähnchen, E; Sachs, W; Trenk, D; Wagner, F | 1 |
| Brunner, F; Kolmayr, U; Kukovetz, WR | 1 |
| Behrenbeck, T; Gülker, H; Heuer, H; Thale, J | 1 |
| Behrenbeck, T; Frenking, B; Gülker, H; Hasfeld, M; Heuer, H | 1 |
| Bender, F; Gülker, H; Haverkamp, W; Hindricks, G; Thale, J | 1 |
| Beermann, J; Gerckens, U; Lüderitz, B; Manz, M | 1 |
| Bender, F; Frenking, B; Gülker, H; Heuer, H; Olbing, B; Thale, J | 1 |
| Barr, WH; Dee, CM; Duerr, H; Hinderling, PH; Seiberling, M; Tendolkar, A | 1 |
| Benz, I; Kohlhardt, M | 1 |
| Blume, H; Zhong, D | 1 |
| Lüderitz, B; Manz, M | 1 |
| Alken, RG; Koytchev, R; Mayer, O | 1 |
| Alken, RG; Greenwood, M; Koytchev, R; Mayer, O; Smith, I | 1 |
| Blume, H; Chen, R; Fieger-Büschges, H; Zhong, D | 1 |
1 review(s) available for propafenone and diprafenone
| Article | Year |
|---|---|
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil | 1993 |
5 trial(s) available for propafenone and diprafenone
| Article | Year |
|---|---|
[Diprafenone--comparative study of anti-arrhythmia therapy with propafenone].
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Monitoring, Physiologic; Propafenone; Random Allocation | 1988 |
Evaluation of the beta-adrenoceptor blocking activity of the Class Ic antiarrhythmic drug diprafenone in man.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Isoproterenol; Male; Propafenone; Propranolol; Random Allocation | 1989 |
Single-dose interaction study of diprafenone HCl and propranolol HCl in healthy volunteers.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Drug Administration Schedule; Drug Combinations; Drug Interactions; Electrocardiography; Exercise Test; Half-Life; Heart Rate; Humans; Male; Propafenone; Propranolol; Rest; Sensitivity and Specificity | 1995 |
Effect of diprafenone on the pharmacokinetics of digoxin.
Topics: Adrenergic Agents; Adult; Anti-Arrhythmia Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Digoxin; Drug Interactions; Humans; Male; Mixed Function Oxygenases; Phenotype; Propafenone | 1996 |
Influence of food on the bioavailability and some pharmacokinetic parameters of diprafenone--a novel antiarrhythmic agent.
Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Arrhythmia Agents; Biological Availability; Cross-Over Studies; Food-Drug Interactions; Humans; Male; Propafenone | 1996 |
26 other study(ies) available for propafenone and diprafenone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Electrophysiological effects of diprafenone, a dimethyl congener of propafenone on guinea-pig ventricular cells.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Electrophysiology; Female; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Propafenone; Sodium Channels | 1992 |
The effects of the stereoisomers of propafenone and diprafenone in guinea-pig heart.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Propafenone; Propanolamines; Stereoisomerism | 1991 |
[Comment on the contribution by C. Hief, K. Frohner, A. Podczeck, W. Kaltenbrunner, M. Nürnberg and K. Steinbach: Value of a provocation test with diprafenone in patients with bifascicular block].
Topics: Ajmaline; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Heart Block; Humans; Propafenone | 1992 |
[Value of a provocation test with diprafenone in patients with bifascicular block].
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrioventricular Node; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Block; Humans; Male; Middle Aged; Propafenone | 1992 |
Characterization of the beta-adrenoceptor blocking property of diprafenone in rats: stereoselective interaction, subtype specificity, and sensitization.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Iodocyanopindolol; Male; Pindolol; Propafenone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stereoisomerism | 1991 |
Direct separation of the enantiomers of propafenone, diprafenone and their major metabolites by high-performance liquid chromatography on modified cellulose and amylose chiral stationary phases.
Topics: Amylose; Anti-Arrhythmia Agents; Cellulose; Chromatography, High Pressure Liquid; Propafenone; Stereoisomerism | 1991 |
Normal-phase high-performance liquid chromatographic procedure for the determination of diprafenone in plasma.
Topics: Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Humans; Propafenone | 1990 |
Block of single cardiac Na+ channels by antiarrhythmic drugs: the effect of amiodarone, propafenone and diprafenone.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Ion Channels; Kinetics; Myocardium; Propafenone; Rats; Sodium | 1988 |
Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Dihydroalprenolol; Dogs; Female; Heart; Isoproterenol; Male; Membranes; Myocardium; Propafenone; Propranolol; Receptors, Adrenergic, beta | 1989 |
Diprafenone for treatment of Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Electric Stimulation; Electrocardiography; Electroencephalography; Female; Humans; Injections, Intravenous; Male; Middle Aged; Propafenone; Refractory Period, Electrophysiological; Tachycardia; Wolff-Parkinson-White Syndrome | 1989 |
Influence of the new class I antiarrhythmic agent diprafenone on the end-systolic pressure-volume relationship (conductance technique).
Topics: Anti-Arrhythmia Agents; Blood Pressure; Cardiac Catheterization; Catheterization; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Propafenone; Tachycardia; Vascular Resistance | 1989 |
On the mechanism of drug-induced blockade of Na+ currents: interaction of antiarrhythmic compounds with DPI-modified single cardiac Na+ channels.
Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Cells, Cultured; Imidazolines; Lidocaine; Myocardium; Prajmaline; Propafenone; Rats; Sodium; Sodium Channels | 1989 |
Pharmacokinetic characterization of the antiarrhythmic drug diprafenone in man.
Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Biological Availability; Humans; Injections, Intravenous; Male; Propafenone | 1989 |
Pharmacokinetics and metabolism of the antiarrhythmic agent [3H]-diprafenone in the rat.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Bile; Biotransformation; Blood Proteins; Chromatography, Thin Layer; Female; Injections, Intravenous; Intestinal Absorption; Male; Propafenone; Protein Binding; Radioimmunoassay; Rats; Rats, Inbred Strains; Subcellular Fractions | 1989 |
Inhibitory effects of diprafenone stereoenantiomers on cardiac Na+ channels.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; In Vitro Techniques; Microelectrodes; Myocardium; Papillary Muscles; Propafenone; Sodium Channels; Stereoisomerism | 1988 |
[Electrophysiologic and hemodynamic effects of the new anti-arrhythmia agent diprafenone].
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Female; Heart Conduction System; Hemodynamics; Humans; Male; Middle Aged; Propafenone | 1987 |
[Treatment of chronic ventricular arrhythmias with the new class Ic anti-arrhythmia agent diprafenon--results of long-term therapy].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Female; Humans; Male; Middle Aged; Prognosis; Propafenone; Time Factors | 1987 |
Use of diprafenone, a new potent propafenone-analogue, in acute experimental myocardial ischaemia and infarction.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Chemical Phenomena; Chemistry; Coronary Disease; Dogs; Female; Heart Conduction System; Heart Ventricles; Male; Myocardial Infarction; Propafenone; Time Factors; Ventricular Fibrillation | 1987 |
[Electrophysiologic effects of diprafenone in supraventricular and ventricular tachycardia].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bundle of His; Cardiomyopathy, Dilated; Coronary Disease; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Propafenone; Tachycardia; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Supraventricular; Wolff-Parkinson-White Syndrome | 1986 |
Assessment of the antiarrhythmic profile of the new class I agent diprafenone.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Dogs; Electrocardiography; Female; Heart Conduction System; Hemodynamics; Male; Propafenone; Propiophenones | 1985 |
Chemically modified cardiac Na+ channels and their sensitivity to antiarrhythmics: is there a hidden drug receptor?
Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Cells, Cultured; Iodates; Lidocaine; Myocardium; Prajmaline; Propafenone; Quinidine; Rats; Receptors, Drug; Sodium Channels; Trypsin | 1994 |
[HPLC determination of diprafenone and its active metabolite 5-hydroxydiprafenone in human plasma].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Propafenone; Spectrophotometry, Ultraviolet | 1994 |
Enantioselective determination of diprafenone in human plasma.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Propafenone; Quality Control; Spectrophotometry, Ultraviolet; Stereoisomerism | 1997 |
Diprafenone.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Interactions; Drugs, Investigational; Humans; In Vitro Techniques; Male; Propafenone; Rats; Sodium Channel Blockers | 1999 |