Page last updated: 2024-08-16

promethazine and theophylline

promethazine has been researched along with theophylline in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's0 (0.00)18.2507
2000's8 (28.57)29.6817
2010's7 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Beranger, S; Désiles, JP; Pascal, JC; Pinhas, H; Poizot, A1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Le Fur, G; Uzan, A1
Carlson, RP; Chang, J; Lewis, AJ; O'Neill-Davis, L1
Cohen, ME; Donowitz, M; el-Sabban, M; Hannah-White, C; Sharp, GW1
Manresa, F1
Julian, A; Plantade, J1
Horlington, M; Watson, PA1
Manganiello, VC; Stoner, J; Vaughan, M1
Kakác, B; Malý, V; Protiva, J; Sarsúnová, M; Schwarz, V1
Bärmig, H; Rasche, P1
Maleev, VV; Pokrovskiĭ, VI1
Ely, EW; Runo, JR1
Caldwell, GG; Evangelisto, M; Jones, WW; Juzwin, SS; Masucci, JJ; Sasso, PP1
HARPER, J1
Borek-Dohalska, L; Fojtikova, V; Martinkova, M; Mináriková, M; Sedláček, J; Šikut, M; Stiborová, M; Vyskočilová, E1
Donovan, MD; Meruva, S1

Reviews

3 review(s) available for promethazine and theophylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Contemporary principles of the therapy of cholera (review of the foreign literature)].
    Sovetskaia meditsina, 1971, Volume: 34, Issue:6

    Topics: Ampicillin; Anti-Bacterial Agents; Benzoates; Bicarbonates; Blood Transfusion; Chloral Hydrate; Chloramphenicol; Cholera; Electrocardiography; Epinephrine; Erythromycin; Glucose; Humans; Hypertonic Solutions; Lactates; Magnesium Sulfate; Mobile Health Units; Norepinephrine; Oleandomycin; Potassium; Potassium Chloride; Promethazine; Sodium Chloride; Strophanthins; Tetracycline; Theophylline; Time Factors; Water-Electrolyte Balance

1971
Treating dyspnea in a patient with advanced chronic obstructive pulmonary disease.
    The Western journal of medicine, 2001, Volume: 175, Issue:3

    Topics: Administration, Inhalation; Aged; Anti-Anxiety Agents; Breathing Exercises; Bronchodilator Agents; Dyspnea; Evidence-Based Medicine; Humans; Lung Diseases, Obstructive; Male; Narcotics; Oxygen Inhalation Therapy; Pneumonectomy; Promethazine; Theophylline

2001

Other Studies

25 other study(ies) available for promethazine and theophylline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
New antihistaminic theophylline or theobromine derivatives.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: Acetylcholine; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Serotonin Antagonists; Skin Tests; Structure-Activity Relationship; Theobromine; Theophylline

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Inhibition of 3', 5'-cyclic AMP phosphodiesterase in the guinea pig lung by a new anti-allergic: 10-(3-quinuclidinylmethyl) phenothiazine (LM 209)].
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 219, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Chlorpheniramine; Cromolyn Sodium; Dexamethasone; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Phenothiazines; Phosphodiesterase Inhibitors; Promethazine; Quinuclidines; Theophylline

1976
Effects of thiazinamium chloride on histamine release from rat peritoneal mast cells and on phosphodiesterase activity in guinea pig lung.
    International archives of allergy and applied immunology, 1986, Volume: 81, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cricetinae; Cromolyn Sodium; Histamine Release; Lung; Mast Cells; Promethazine; Theophylline

1986
Effects of Ca2+, theophylline and promethazine on protein phosphorylation in intact cells of rabbit ileum. Correlation with active Na and Cl absorption.
    FEBS letters, 1987, Sep-14, Volume: 221, Issue:2

    Topics: Animals; Calcimycin; Calcium; Chlorides; Electrophoresis, Polyacrylamide Gel; Female; Ileum; Intestinal Absorption; Membrane Proteins; Microvilli; Molecular Weight; Phosphorylation; Promethazine; Rabbits; Sodium; Theophylline

1987
Should symptoms--namely cough and dyspnoea--be treated?
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Codeine; Cough; Diazepam; Dyspnea; Ethanol; Humans; Oxygen Inhalation Therapy; Promethazine; Theophylline

1986
[Alpolone and allergy in otorhinolaryngology (54 cases)].
    Journal francais d'oto-rhino-laryngologie, audio-phonologie et chirurgie maxillo-faciale, 1969, Volume: 18, Issue:4

    Topics: Acetates; Barbiturates; Chlorides; Drug Synergism; Humans; Prednisolone; Promethazine; Respiratory Hypersensitivity; Salicylates; Theophylline

1969
Inhibition of 3'5'-cyclic-AMP phosphodiesterase by some platelet aggregation inhibitors.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Animals; Blood Platelets; Cattle; Cell Aggregation; Chlorine; Chlorpromazine; Cyclic AMP; Esterases; Female; Nucleosides; Phenothiazines; Promethazine; Theophylline

1970
Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:12

    Topics: Acetylcholine; Angiotensin II; Animals; Aspirin; Bradykinin; Culture Techniques; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Indomethacin; Isoproterenol; Lung; Peptides; Promethazine; Stimulation, Chemical; Theophylline

1973
[Thin layer chromatography without binding agent in drug analysis. 8. Separation and quantitative determination of antihistaminics and ataraxics].
    Die Pharmazie, 1966, Volume: 21, Issue:12

    Topics: Aluminum; Anti-Arrhythmia Agents; Benactyzine; Chlorpromazine; Chromatography, Thin Layer; Guaiacol; Histamine H1 Antagonists; Imidazoles; Infrared Rays; Iodine; Meprobamate; Methods; Oxides; Parasympatholytics; Phenmetrazine; Promethazine; Spectrophotometry; Theophylline; Tranquilizing Agents; Ultraviolet Rays

1966
[Atypical course in postpartum eclampsia? A case report].
    Zentralblatt fur Gynakologie, 1972, Dec-02, Volume: 94, Issue:48

    Topics: Adult; Chlorpromazine; Diazepam; Eclampsia; Female; Humans; Hypertension; Infant, Newborn; Infant, Premature; Ischemic Attack, Transient; Nicotinic Acids; Pregnancy; Pressure Ulcer; Promethazine; Puerperal Disorders; Theophylline; Twins

1972
The use of on-line and off-line chromatographic extraction techniques coupled with mass spectrometry for support of in vivo and in vitro assays in drug discovery.
    Current topics in medicinal chemistry, 2001, Volume: 1, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Caco-2 Cells; Chromatography, Liquid; Cimetidine; Drug Evaluation, Preclinical; Gas Chromatography-Mass Spectrometry; Histamine H1 Antagonists; Humans; Hydrochlorothiazide; Pharmaceutical Preparations; Phosphodiesterase Inhibitors; Promethazine; Theophylline

2001
Prevention and treatment of travel sickness with promethazine chlorotheophyllinate.
    Lancet (London, England), 1951, May-26, Volume: 1, Issue:6665

    Topics: Humans; Motion Sickness; Promethazine; Theophylline

1951
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline

2017
Effects of Drug-Polymer Interactions on Tablet Properties During the Development of Abuse-Deterrent Dosage Forms.
    AAPS PharmSciTech, 2019, Jan-28, Volume: 20, Issue:3

    Topics: Delayed-Action Preparations; Dextromethorphan; Dosage Forms; Ketoprofen; Polyethylene Glycols; Promethazine; Solubility; Substance-Related Disorders; Tablets; Theophylline

2019