Page last updated: 2024-08-16

promethazine and naloxone

promethazine has been researched along with naloxone in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199010 (37.04)18.7374
1990's3 (11.11)18.2507
2000's7 (25.93)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Forbes, AR; Hickey, RF; Hsu, HO1
Cooper, JR; Mattsson, JL1
Arthur, A; Miller, R; Sakamoto, E; Stratigos, GT1
Friedman, E; Gershon, S; Hine, B; Torrelio, M1
Blumer, JL; Buck, ML1
Aasen, AO; Pillgram-Larsen, J; Ruud, TE; Stadaas, JO2
Rabinov, W; Samuels, SI1
Cicero, TJ; Meyer, ER; Wilcox, CE1
Bell, RD; Cicero, TJ; Meyer, ER1
Chung, YH; Kamei, C; Miyake, H; Tasaka, K1
Aasen, AO; Naess, F; Roeise, O; Stadaas, JO; Waage, A1
Brandon, MJ; Geiger, MJ; Kearney, MM; Kent, V; Natale, A; Newby, KH; Wase, A1
Benraad, B; Dirksen, R; Slappendel, R; van Limbeek, J; Weber, EW1
Barry, JJ; Branagan, HC; Richardson, CA; Sartain, JB1
Corrêa Benedet Baesso, K; De Sá Soares, A; Schuelter-Trevisol, F; Zapelini do Nascimento, D1

Reviews

3 review(s) available for promethazine and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Phenothiazine-associated apnea in two siblings.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:3

    Topics: Apnea; Bradycardia; Chlorpromazine; Drug Therapy, Combination; Family; Female; Humans; Infant; Male; Meperidine; Naloxone; Phenothiazines; Promethazine; Urinary Tract Infections

1991

Trials

2 trial(s) available for promethazine and naloxone

ArticleYear
Itching after intrathecal morphine. Incidence and treatment.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:10

    Topics: Aged; Analgesics, Opioid; Antipruritics; Arthroplasty, Replacement, Hip; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Injections, Spinal; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Promethazine; Pruritus

2000
Effect of combining naloxone and morphine for intravenous patient-controlled analgesia.
    Anesthesiology, 2003, Volume: 99, Issue:1

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Antiemetics; Drug Therapy, Combination; Female; Humans; Hysterectomy; Mental Recall; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Postoperative Nausea and Vomiting; Promethazine; Pruritus

2003

Other Studies

22 other study(ies) available for promethazine and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Morphine decreases peripheral vascular resistance and increases capacitance in man.
    Anesthesiology, 1979, Volume: 50, Issue:2

    Topics: Blood Pressure; Drug Interactions; Humans; Morphine; Naloxone; Promethazine; Vascular Resistance; Vasodilation

1979
Control of radiation-induced emesis with promethazine, cimetidine, thiethylperazine, or naloxone.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Animals; Chemoreceptor Cells; Cimetidine; Dog Diseases; Dogs; Guanidines; Male; Naloxone; Promethazine; Radiation Injuries; Radiation Injuries, Experimental; Thiethylperazine; Vomiting

1979
Serious postextraction hemorrhage into the submandibular space: report of case.
    Journal of the American Dental Association (1939), 1975, Volume: 90, Issue:3

    Topics: Blood Pressure; Cheyne-Stokes Respiration; Female; Hematoma; Humans; Intubation, Intratracheal; Lidocaine; Meperidine; Middle Aged; Mouth Floor; Naloxone; Oral Hemorrhage; Oxygen; Penicillins; Promethazine; Pulse; Respiration; Respiratory Insufficiency; Tooth Extraction

1975
Tetrahydrocannabinol-attenuated abstinence and induced rotation in morphine-dependent rats: possible involvement of dopamine.
    Neuropharmacology, 1975, Volume: 14, Issue:8

    Topics: Animals; Behavior; Cannabis; Dopamine; Dronabinol; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Promethazine; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1975
Multitherapy: a new treatment regimen in endotoxemia.
    Progress in clinical and biological research, 1987, Volume: 236A

    Topics: Animals; Drug Therapy, Combination; Endotoxins; Escherichia coli; Hemodynamics; Kallikreins; Ketanserin; Methylprednisolone; Naloxone; Oxygen; Promethazine; Protease Inhibitors; Shock, Septic; Swine

1987
Hemodynamic consequences of multitherapy pretreatment in experimental endotoxemia.
    Progress in clinical and biological research, 1987, Volume: 236A

    Topics: Animals; Drug Therapy, Combination; Endotoxins; Escherichia coli; Hemodynamics; Ketanserin; Lipopolysaccharides; Methylprednisolone; Naloxone; Oxygen; Promethazine; Protease Inhibitors; Pulmonary Circulation; Shock, Septic; Swine

1987
Difficulty reversing drug-induced coma in a patient with sleep apnea.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:11

    Topics: Adult; Coma; Humans; Hypnotics and Sedatives; Male; Meperidine; Naloxone; Physostigmine; Promethazine; Respiration; Sleep Apnea Syndromes

1986
Effect of alpha-adrenergic blockers on naloxone-binding in brain.
    Biochemical pharmacology, 1974, Aug-15, Volume: 23, Issue:16

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Brain; In Vitro Techniques; Lysergic Acid Diethylamide; Naloxone; Narcotics; Promethazine; Rats; Receptors, Drug; Tritium

1974
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Chemical; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Pentobarbital; Phenoxybenzamine; Phentolamine; Promethazine; Propranolol; Rats; Substance Withdrawal Syndrome; Time Factors

1974
Analgesic effect of histamine induced by intracerebral injection into mice.
    Agents and actions, 1984, Volume: 15, Issue:3-4

    Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time

1984
Effects of a combined drug regimen on tumour necrosis factor and plasma kallikrein activity in experimental endotoxaemia.
    The European journal of surgery = Acta chirurgica, 1994, Volume: 160, Issue:2

    Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli Infections; Hemodynamics; Kallikreins; Ketanserin; Methylprednisolone; Naloxone; Promethazine; Protease Inhibitors; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1994
Evaluation of the safety and efficacy of deep sedation for electrophysiology procedures administered in the absence of an anesthetist.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:7

    Topics: Adjuvants, Anesthesia; Airway Obstruction; Anesthesia, Intravenous; Anesthesiology; Anesthetics, Intravenous; Blood Pressure; Consciousness; Cost Control; Electrocardiography; Electrophysiology; Evaluation Studies as Topic; Female; Fentanyl; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Laboratories; Length of Stay; Male; Memory; Meperidine; Midazolam; Middle Aged; Monitoring, Physiologic; Naloxone; Narcotic Antagonists; Oximetry; Oxygen; Promethazine; Safety

1997
Use of tracking drugs for the search of intra-hospital adverse reactions: a pharmacovigilance study.
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 04-26, Volume: 46, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Cross-Sectional Studies; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Flumazenil; Hospitals; Humans; Loperamide; Naloxone; Pharmacovigilance; Promethazine

2022