Page last updated: 2024-08-16

promethazine and metoclopramide

promethazine has been researched along with metoclopramide in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19908 (20.51)18.7374
1990's2 (5.13)18.2507
2000's9 (23.08)29.6817
2010's19 (48.72)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Marsden, CD; Parkes, JD; Tarsy, D2
Peitersen, E; Vesterhauge, S1
Marsden, CD; Pycock, C; Tarsy, D1
Blaha, CD; Lane, RF1
Francis, D; Houlton, P; Reynolds, F; Vella, L1
McMurray, GN1
Scherl, ER; Wilson, JF1
Yaddanapudi, LN1
Accorsi, P; Aguzzoli, L; Carossino, E; Crotti, M; Gargano, G; Masellis, G1
Bsat, FA; Hoffman, DE; Seubert, DE1
Gan, TJ; Habib, AS1
Amini, R; Hays, DP; Patanwala, AE; Rosen, P1
Khine, PP; Omar, SZ; Tan, PC; Vallikkannu, N1
Barrett, TW; DiPersio, DM; Jack, M; Jenkins, CA; Lee, P; McCoin, NS; Singleton, LM; Slovis, CM; Storrow, AB; Zhou, C1
Haas, DM; Lehmann, AS; McCormick, CL; Renbarger, JL; Rouse, C; Topletz, AR1
Barlow-Savko, E; Carlson, JN; Forehand, B1
Furyk, JS; McKenzie, S; Meek, R1
Clark, SM; Dutta, E; Hankins, GD1
Gray, R; Lopes, V; Matteson, KA; Mayhall, EA1
Egerton-Warburton, D; Furyk, JS; Meek, RA1
Barton, SJ; Berghella, V; Boelig, RC; Edwards, SJ; Kelly, AJ; Saccone, G1
Fu, R; Hansen, ML; Laurie, A; Ma, OJ; Meckler, GD; Pacheco, S; Sheridan, DC1
Garra, G; Singer, AJ; Thode, HC1
Banting, J; Meriano, T1
Barney, EZ; Fuller, ME; Habib, AS1

Reviews

8 review(s) available for promethazine and metoclopramide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Evaluation and treatment of hyperemesis gravidarum].
    Minerva ginecologica, 2001, Volume: 53, Issue:6

    Topics: Administration, Oral; Adult; Antiemetics; Birth Weight; Chlorpromazine; Diagnosis, Differential; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hyperemesis Gravidarum; Infant, Newborn; Metoclopramide; Monitoring, Physiologic; Pregnancy; Promethazine; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors

2001
The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report.
    Journal of clinical anesthesia, 2005, Volume: 17, Issue:1

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Dimenhydrinate; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Multicenter Studies as Topic; North America; Ondansetron; Postoperative Nausea and Vomiting; Promethazine; Randomized Controlled Trials as Topic; Treatment Failure

2005
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Vomiting

2010
The outpatient management and special considerations of nausea and vomiting in pregnancy.
    Seminars in perinatology, 2014, Volume: 38, Issue:8

    Topics: Ambulatory Care; Antiemetics; Diet Therapy; Doxylamine; Female; Fluid Therapy; Gastroesophageal Reflux; Histamine H1 Antagonists; Humans; Hyperemesis Gravidarum; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Promethazine; Pyridoxine; Severity of Illness Index; Vitamin B Complex

2014
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Randomized Controlled Trials as Topic; Visual Analog Scale; Vomiting

2015
Interventions for treating hyperemesis gravidarum.
    The Cochrane database of systematic reviews, 2016, May-11, Issue:5

    Topics: Acupuncture Therapy; Adrenal Cortex Hormones; Antiemetics; Female; Humans; Hydrocortisone; Hyperemesis Gravidarum; Metoclopramide; Ondansetron; Placebo Effect; Prednisolone; Pregnancy; Promethazine; Pyridoxine

2016
Sea State Green.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2016,summer, Volume: 16, Issue:2

    Topics: Acupressure; Antiemetics; Cholinergic Antagonists; Dopamine Antagonists; Emergency Medical Technicians; Histamine Antagonists; Humans; Meclizine; Metoclopramide; Military Personnel; Motion Sickness; Ondansetron; Promethazine; Scopolamine

2016

Trials

9 trial(s) available for promethazine and metoclopramide

ArticleYear
Letter: Metoclopramide in parkinsonism.
    Lancet (London, England), 1975, May-31, Volume: 1, Issue:7918

    Topics: Clinical Trials as Topic; Humans; Levodopa; Metoclopramide; Nausea; Parkinson Disease; Promethazine; Vomiting

1975
Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:4

    Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Metoclopramide; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Parkinson Disease, Secondary; Pimozide; Placebos; Promethazine

1975
Comparison of the antiemetics metoclopramide and promethazine in labour.
    British medical journal (Clinical research ed.), 1985, Apr-20, Volume: 290, Issue:6476

    Topics: Clinical Trials as Topic; Consciousness; Double-Blind Method; Female; Humans; Meperidine; Metoclopramide; Nausea; Obstetric Labor Complications; Pain; Pregnancy; Promethazine; Vomiting

1985
An evaluation of metoclopramide as an anti-emetic in seasickness.
    Postgraduate medical journal, 1973, Volume: 49 Suppl 4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Male; Metoclopramide; Middle Aged; Motion Sickness; Placebos; Promethazine; Vomiting

1973
Comparison of dihydroergotamine with metoclopramide versus meperidine with promethazine in the treatment of acute migraine.
    Headache, 1995, Volume: 35, Issue:5

    Topics: Acute Disease; Adult; Ambulatory Care; Dihydroergotamine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Meperidine; Metoclopramide; Middle Aged; Migraine Disorders; Promethazine; Prospective Studies

1995
Evaluation of two antiemetic agents during outpatient gynaecological surgery.
    Singapore medical journal, 1994, Volume: 35, Issue:3

    Topics: Abortion, Induced; Adult; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, General; Chi-Square Distribution; Dilatation and Curettage; Female; Humans; Metoclopramide; Pregnancy; Promethazine; Statistics, Nonparametric; Vomiting

1994
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
    Journal of perinatology : official journal of the California Perinatal Association, 2003, Volume: 23, Issue:7

    Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Promethazine; Prospective Studies; Pyridoxine; Treatment Outcome; Vomiting

2003
Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial.
    Obstetrics and gynecology, 2010, Volume: 115, Issue:5

    Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Pregnancy; Promethazine; Treatment Outcome

2010
A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Promethazine; Treatment Outcome; Young Adult

2011

Other Studies

22 other study(ies) available for promethazine and metoclopramide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The effects of some drugs on the caloric induced nystagmus.
    Advances in oto-rhino-laryngology, 1979, Volume: 25

    Topics: Amphetamine; Atropine; Caffeine; Caloric Tests; Cyclizine; Eye Movements; Humans; Metoclopramide; Promethazine; Scopolamine; Thiethylperazine; Vestibule, Labyrinth

1979
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents

1975
Chronic treatment with classical and atypical antipsychotic drugs differentially decreases dopamine release in striatum and nucleus accumbens in vivo.
    Neuroscience letters, 1987, Jul-22, Volume: 78, Issue:2

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Haloperidol; Male; Metoclopramide; Nucleus Accumbens; Promethazine; Rats; Rats, Inbred Strains; Septal Nuclei; Thioridazine

1987
Letter: Pyridoxine in parkinsonism.
    Lancet (London, England), 1973, Nov-03, Volume: 302, Issue:7836

    Topics: Dihydroxyphenylalanine; Drug Antagonism; Drug Interactions; Humans; Metoclopramide; Movement Disorders; Parkinson Disease; Promethazine; Pyridoxine

1973
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
    BMC pregnancy and childbirth, 2013, Jun-20, Volume: 13

    Topics: Adult; Antiemetics; Female; Humans; Metoclopramide; Morning Sickness; Ondansetron; Pilot Projects; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prochlorperazine; Promethazine; Receptors, Serotonin, 5-HT3; Severity of Illness Index; Treatment Outcome; Young Adult

2013
Antiemetic use in US EDs.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antiemetics; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Middle Aged; Ondansetron; Practice Patterns, Physicians'; Prochlorperazine; Promethazine; United States; Young Adult

2014
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopramide; Morning Sickness; Muscarinic Antagonists; Nausea; Ondansetron; Pregnancy; Primary Health Care; Prochlorperazine; Promethazine; Scopolamine; Vomiting

2014
Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:7

    Topics: Adult; Antiemetics; Cohort Studies; Emergency Service, Hospital; Female; Humans; Hypotension, Orthostatic; Ketosis; Length of Stay; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Pregnancy Trimester, First; Prochlorperazine; Promethazine; Retrospective Studies; Treatment Outcome; Young Adult

2015
Relative Effectiveness of Dopamine Antagonists for Pediatric Migraine in the Emergency Department.
    Pediatric emergency care, 2018, Volume: 34, Issue:3

    Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Cohort Studies; Dopamine Antagonists; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Ketorolac; Male; Metoclopramide; Migraine Disorders; Pain Measurement; Prochlorperazine; Promethazine; Retrospective Studies; Treatment Failure; Treatment Outcome

2018
Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective.
    The Journal of emergency medicine, 2016, Volume: 50, Issue:6

    Topics: Adult; Antiemetics; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Retrospective Studies; Vomiting

2016
Comparison of metoclopramide and promethazine for the treatment of postoperative nausea and vomiting in the post-anesthesia care unit: A retrospective database analysis.
    Journal of clinical anesthesia, 2020, Volume: 60

    Topics: Anesthesia; Antiemetics; Double-Blind Method; Humans; Metoclopramide; Ondansetron; Postoperative Nausea and Vomiting; Promethazine; Retrospective Studies; Vomiting

2020