promethazine has been researched along with clozapine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (31.03) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, GH; Unger, SH | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Peters, JU | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bruno, C; Carrieri, A; Cavalluzzi, MM; Franchini, C; Giannuzzi, G; Illario, M; Lentini, G; Lovece, A; Polimeno, L; Pracella, R; Rusciano, MR; Viale, M | 1 |
| Kudrin, VS; Mineyeva, MF; Rayevsky, KS | 1 |
| Costa, E; Guidotti, A; Revuelta, A; Zivkovic, B | 1 |
| Fielding, S; Lal, H; Marky, M | 1 |
| Marsden, CD; Pycock, C; Tarsy, D | 1 |
| Manian, AA; Palmer, GC; Spiker, MD | 1 |
| Bergman, J; Spealman, RD | 1 |
| Blaha, CD; Lane, RF | 1 |
| Schechter, MD | 1 |
| Bathó, N; Chevalier, J; Cremieux, A; Csík, V; Molnár, J | 1 |
| Chakraborty, R; Chatterjee, A | 1 |
3 review(s) available for promethazine and clozapine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Polypharmacology - foe or friend?
Topics: Animals; Communicable Diseases; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Polypharmacology; Safety | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
26 other study(ies) available for promethazine and clozapine
| Article | Year |
|---|---|
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cattle; Humans; Molecular Docking Simulation; Piperidines; Protein Conformation; Protein Kinase Inhibitors; Thiazoles | 2016 |
The effect of neuroleptics on brain tyrosine hydroxylase.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Brain; Clozapine; Fluphenazine; Haloperidol; Hypothalamus; Male; Promethazine; Rats; Tyrosine 3-Monooxygenase | 1978 |
Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Catecholamines; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzothiepins; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothalamus; Kinetics; Male; Norepinephrine; Pimozide; Promethazine; Rats; Thioridazine; Tyrosine 3-Monooxygenase | 1975 |
Effect of neuroleptic drugs on mouse jumping induced by L-DOPA in amphetamine treated mice.
Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Levodopa; Male; Mice; Pimozide; Promethazine; Psychotropic Drugs; Stereotyped Behavior; Thioridazine; Tranquilizing Agents | 1976 |
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents | 1975 |
Action of neuroleptic agents on histamine-sensitive adenylate cyclase in rabbit cerebral cortex.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Chlorpromazine; Clozapine; Haloperidol; Histamine; Promethazine; Rabbits; Thioridazine; Tranquilizing Agents | 1976 |
Some behavioral effects of histamine H1 antagonists in squirrel monkeys.
Topics: Animals; Behavior, Animal; Chlordiazepoxide; Chlorpheniramine; Cimetidine; Clozapine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diphenhydramine; Electroshock; Feeding Behavior; Histamine H1 Antagonists; Male; Promethazine; Saimiri; Self Administration; Tripelennamine | 1986 |
Chronic treatment with classical and atypical antipsychotic drugs differentially decreases dopamine release in striatum and nucleus accumbens in vivo.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Haloperidol; Male; Metoclopramide; Nucleus Accumbens; Promethazine; Rats; Rats, Inbred Strains; Septal Nuclei; Thioridazine | 1987 |
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine | 1980 |
Interaction between tricyclic psychopharmacons and some antibiotics.
Topics: Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Clozapine; Drug Interactions; Escherichia coli; Imipramine; Plasmids; Promethazine | 1995 |
Clozapine-induced oculogyric crises.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Injections, Intramuscular; Male; Ocular Motility Disorders; Promethazine; Schizophrenia | 2007 |