Page last updated: 2024-08-16

promethazine and caffeine

promethazine has been researched along with caffeine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199020 (54.05)18.7374
1990's1 (2.70)18.2507
2000's9 (24.32)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Peitersen, E; Vesterhauge, S1
Middleton, RA1
Upton, LG1
Curea, E; Martinovici, M1
Mims, M; Stewart, JJ; Wood, CD; Wood, MJ1
Filippova, LM; Rapoport, IA; Zhurkov, VS1
Frank, GB; Jhamandas, K1
Doenicke, A; Konrad, T; Kugler, J; Laub, M; Wittmann, R1
Monnat, A1
Mason, RG; Read, MS; Saba, SR; Shermer, RW1
Filipescu, A; Spirescu, J1
May, W1
von Albert, HH1
Guignard, J; Le Gouas, JJ; Rousseau, L1
Chan, HL1
Baroth, V; Breitkreutz, J; Gröning, R; Müller, RS1
SCHOLTZ, HJ1
WINBERG, J1
AVIADO, DM; SALEM, H1
GRANT, WM; PECZON, JD1
TURI, P1
Hara, H; Yokoyama, A1
Bai, YQ; Gao, JY; Huang, M; Liang, QL; Luo, GA; Wang, YM; Zhai, ZG1
Jiang, JG; Song, GS; Zhang, XR; Zhang, YH1

Reviews

3 review(s) available for promethazine and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
ANTITUSSIVE DRUGS, WITH SPECIAL REFERENCE TO A NEW THEORY FOR THE INITATION OF THE COUGH REFLEX AND THE INFLUENCE OR BRONCHODILATORS.
    The American journal of the medical sciences, 1964, Volume: 247

    Topics: Acetaminophen; Aerosols; Aminophylline; Analgesics; Analgesics, Non-Narcotic; Animals; Antimony; Antipyretics; Antitussive Agents; Ascorbic Acid; Bronchodilator Agents; Caffeine; Codeine; Cough; Dogs; Electric Stimulation; Electrophysiology; Expectorants; Histamine H1 Antagonists; Hypnotics and Sedatives; Ion Exchange Resins; Noscapine; Parasympatholytics; Pharmacology; Phenothiazines; Promethazine; Reflex; Research; Sodium Salicylate; Sympathomimetics

1964
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents

1964

Trials

5 trial(s) available for promethazine and caffeine

ArticleYear
Postoperative evaluation of combined analgesic/sedative.
    Dental survey, 1978, Volume: 54, Issue:2

    Topics: Anxiety; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Humans; Pain, Postoperative; Phenacetin; Promethazine

1978
Evaluation of sedative/analgesic combination for postoperative pain.
    Oral surgery, oral medicine, and oral pathology, 1979, Volume: 47, Issue:6

    Topics: Anxiety; Aspirin; Caffeine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Pain, Postoperative; Phenacetin; Placebos; Promethazine; Tooth Extraction

1979
Effectiveness and duration of intramuscular antimotion sickness medications.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:11

    Topics: Caffeine; Ephedrine; Female; Humans; Injections, Intramuscular; Male; Motion Sickness; Promethazine; Scopolamine; Time Factors

1992
[Electroencephalographic determination of vigilance following DL-propiramfumarate].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Amides; Analgesics; Aspirin; Attention; Caffeine; Clinical Trials as Topic; Codeine; Drug Synergism; Electroencephalography; Electrooculography; Ethanol; Eye Movements; Female; Fumarates; Humans; Male; Phenacetin; Phenobarbital; Piperidines; Placebos; Promethazine; Propionates; Pyridines

1974
[The treatment of seasickness with Kinetosin].
    Das Deutsche Gesundheitswesen, 1965, Jul-08, Volume: 20, Issue:27

    Topics: Caffeine; Clinical Trials as Topic; Ephedrine; Humans; Motion Sickness; Promethazine

1965

Other Studies

29 other study(ies) available for promethazine and caffeine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effects of some drugs on the caloric induced nystagmus.
    Advances in oto-rhino-laryngology, 1979, Volume: 25

    Topics: Amphetamine; Atropine; Caffeine; Caloric Tests; Cyclizine; Eye Movements; Humans; Metoclopramide; Promethazine; Scopolamine; Thiethylperazine; Vestibule, Labyrinth

1979
[Thin-layer chromatography and UV spectrophotometry in qualitative and quantitative analysis of drugs. II. Determination of promethazine in the presence of caffeine (or codeine) in drug mixtures].
    Annales pharmaceutiques francaises, 1975, Volume: 33, Issue:10

    Topics: Caffeine; Chromatography, Thin Layer; Codeine; Drug Combinations; Promethazine; Spectrophotometry, Ultraviolet

1975
Investigation of the mutagenic activity of phenothiazines and other drug preparations.
    Soviet genetics, 1973, Dec-01, Volume: 7, Issue:8

    Topics: Animals; Caffeine; Chromosome Aberrations; Drosophila melanogaster; Gene Frequency; Genes, Lethal; Haloperidol; Larva; Mutagens; Mutation; Phenothiazines; Promethazine; Sex Chromosomes; Structure-Activity Relationship

1973
Effects of drugs acting alone and in combination on the motor activity of intact mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Diphenhydramine; Female; Glutamates; Hydroxybutyrates; Lactones; Meperidine; Meprobamate; Mice; Motor Activity; Nikethamide; Phenobarbital; Picrotoxin; Promethazine; Reflex; Scopolamine; Seizures; Strychnine; Tranquilizing Agents

1970
[Comparative study of Lyell's and Stevens-Johnson syndromes: etiologic role of drugs].
    Schweizerische medizinische Wochenschrift, 1972, Dec-23, Volume: 102, Issue:51

    Topics: Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Codeine; Female; Humans; Hydantoins; Infant; Infant, Newborn; Male; Middle Aged; Penicillins; Phenacetin; Phenobarbital; Phenolphthaleins; Phenylbutazone; Promethazine; Stevens-Johnson Syndrome; Sulfamethoxypyridazine; Vaccines

1972
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
    Thrombosis et diathesis haemorrhagica, 1972, Feb-29, Volume: 27, Issue:1

    Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds

1972
[The pain syndrome of the edentulous alveolar crest and its treatment].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1969, Volume: 70, Issue:2

    Topics: Administration, Topical; Alveolar Process; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Caffeine; Chlorpromazine; Codeine; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Mouth, Edentulous; Pain; Phenobarbital; Procaine; Promethazine

1969
[Detection of sedative effect by electronystagmography].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:9

    Topics: Amphetamine; Antihypertensive Agents; Caffeine; Chlorpromazine; Dibenzazepines; Electric Stimulation; Humans; Hypnotics and Sedatives; Imidazoles; Methods; Pentobarbital; Phenmetrazine; Phenothiazines; Phenytoin; Promethazine; Thiethylperazine; Vestibular Function Tests

1969
[Pneumopathies in children due to ingestion of petroleum].
    Annales de pediatrie, 1969, Apr-02, Volume: 16, Issue:4

    Topics: Bronchography; Caffeine; Child, Preschool; Female; Humans; Infant; Leukocytosis; Lymphocytosis; Male; Oxygen Inhalation Therapy; Oxytetracycline; Penicillins; Petroleum; Pneumonia; Promethazine; Pulmonary Emphysema; Tachycardia; Tetracycline

1969
Fixed drug eruptions. A study of 20 occurrences in Singapore.
    International journal of dermatology, 1984, Volume: 23, Issue:9

    Topics: Adult; Aged; Ampicillin; Analgesics; Antipyrine; Aspirin; Caffeine; Chlorothiazide; Drug Combinations; Drug Eruptions; Female; Humans; Male; Methimazole; Middle Aged; Phenacetin; Phenolphthaleins; Promethazine; Pyrazoles; Pyrazolones; Pyridones; Singapore; Tetracyclines

1984
Nanoparticles in plant extracts: influence of drugs on the formation of nanoparticles and precipitates in black tea infusions.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 15, Issue:2

    Topics: Caffeine; Chemical Precipitation; Fluphenazine; Humans; Microscopy, Electron, Scanning; Molecular Structure; Particle Size; Plant Extracts; Promethazine; Spectrum Analysis; Tea

2002
[VESTIBULAR VERTIGO AND ITS TREATMENT BY DRUGS].
    Zeitschrift fur arztliche Fortbildung, 1963, Dec-15, Volume: 57

    Topics: Caffeine; Ephedrine; Humans; Meclizine; Meniere Disease; Perphenazine; Prochlorperazine; Promethazine; Thiazines; Vertigo

1963
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
    Svenska lakartidningen, 1964, Mar-25, Volume: 61

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Caffeine; Ephedrine; Female; Fetal Death; Fetal Development; Humans; Infant; Infant, Newborn; Infant, Premature; Meclizine; Pharmacology; Phenobarbital; Pregnancy; Prochlorperazine; Promethazine

1964
ASSAY PROCEDURE FOR PHARMACEUTICAL COMBINATIONS OF ASPIRIN, PHENACETIN, CAFFEINE, AND ITOBARBITAL WITH PHENOTHIAZINE DERIVATIVES. I.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Anti-Bacterial Agents; Antipsychotic Agents; Aspirin; Barbiturates; Caffeine; Chemistry, Pharmaceutical; Chlorpromazine; Phenacetin; Phenothiazines; Promethazine; Research; Thiethylperazine; Thioridazine

1964
Multiple fixed drug eruption due to drug combination.
    Contact dermatitis, 2005, Volume: 52, Issue:6

    Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caffeine; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Patch Tests; Promethazine; Salicylamides

2005
An HPLC-ESI-MS method for simultaneous determination of fourteen metabolites of promethazine and caffeine and its application to pharmacokinetic study of the combination therapy against motion sickness.
    Journal of pharmaceutical and biomedical analysis, 2012, Mar-25, Volume: 62

    Topics: Caffeine; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Motion Sickness; Promethazine; Spectrometry, Mass, Electrospray Ionization

2012
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:1

    Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013