Compounds > promethazine
Page last updated: 2024-08-16

promethazine and bufuralol

promethazine has been researched along with bufuralol in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Inoue, K; Kamataki, T; Kume, T; Nakamura, K; Ohashi, N; Shimada, N; Yokoi, T1
Edeki, T; He, N; Shockley, D; Zhang, WQ1

Other Studies

5 other study(ies) available for promethazine and bufuralol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes.
    Pharmacogenetics, 1996, Volume: 6, Issue:5

    Topics: Antibodies; B-Lymphocytes; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Ethanolamines; Histamine H1 Antagonists; Humans; Hydroxylation; Mass Spectrometry; Microsomes, Liver; Promethazine

1996
Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes.
    European journal of clinical pharmacology, 2002, Volume: 57, Issue:12

    Topics: Aryl Hydrocarbon Hydroxylases; Chlorpheniramine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Ethanolamines; Histamine H1 Antagonists; Humans; Hydroxylation; Microsomes, Liver; Promethazine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tolbutamide

2002