Page last updated: 2024-08-16

promethazine and apomorphine

promethazine has been researched along with apomorphine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Korf, J; Westerink, BH1
Marsden, CD; Pycock, C; Tarsy, D1
Morgenroth, VH; Roth, RH; Walters, JR1
Bartholini, G; Gadea-Ciria, M; Lloyd, KG; Stadler, H1
Baldessarini, RJ; Tarsy, D1
Balsara, JJ; Chandorkar, AG; Dhavare, BS; Nandal, NV1
ISAACS, B; MACARTHUR, JG1
AHMED, A1
DHAWAN, BN; GUPTA, GP; SAXENA, PN1

Reviews

2 review(s) available for promethazine and apomorphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Animals; Apomorphine; Butyrates; Calcium; Chloral Hydrate; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Electric Conductivity; Haloperidol; Halothane; Hydroxybutyrates; Lactones; Male; Medulla Oblongata; Models, Biological; Neurons; Norepinephrine; Pargyline; Promethazine; Rats; Time Factors; Tyrosine 3-Monooxygenase; Vas Deferens

1974

Other Studies

14 other study(ies) available for promethazine and apomorphine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra

1976
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents

1975
Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine.
    Brain research, 1973, Jun-15, Volume: 55, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Basal Ganglia; Cats; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dopamine; Promethazine; Receptors, Cholinergic; Synaptic Transmission

1973
Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.
    Neuropharmacology, 1974, Volume: 13, Issue:10-11

    Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Catecholamines; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Humans; Locomotion; Male; Methyltyrosines; Phenobarbital; Promethazine; Rats; Reserpine; Stereotyped Behavior; Synapses; Time Factors

1974
Effects of L-histidine and promethazine on apomorphine and amantadine stereotypy in rats.
    Psychopharmacology, 1983, Volume: 79, Issue:4

    Topics: Amantadine; Animals; Apomorphine; Dose-Response Relationship, Drug; Histidine; Humans; Male; Promethazine; Rats; Rats, Inbred Strains; Stereotyped Behavior

1983
Influence of chlorpromazine and promethazine on vomiting induced with apomorphine in man.
    Lancet (London, England), 1954, Sep-18, Volume: 267, Issue:6838

    Topics: Apomorphine; Autonomic Agents; Chlorpromazine; Histamine H1 Antagonists; Humans; Male; Promethazine; Vomiting

1954
Studies on the antiemetic efficacy of chlorpromazine and promethazine against apomorphine induced emesis in dogs.
    Indian journal of medical sciences, 1957, Volume: 11, Issue:2

    Topics: Animals; Antiemetics; Apomorphine; Chlorpromazine; Dogs; Histamine H1 Antagonists; Promethazine; Vomiting

1957
Antagonism of apomorphine-induced pecking in pigeons.
    British journal of pharmacology and chemotherapy, 1961, Volume: 16

    Topics: Animals; Antiemetics; Apnea; Apomorphine; Central Nervous System; Columbidae; Diphenhydramine; Emetics; Lysergic Acid Diethylamide; Promethazine; Psychopharmacology; Radiography; Scopolamine; Thiazoles; Vomiting

1961