Page last updated: 2024-08-16

promazine and nortriptyline

promazine has been researched along with nortriptyline in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199014 (58.33)18.7374
1990's1 (4.17)18.2507
2000's5 (20.83)29.6817
2010's4 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Bellman, K; Knegtel, RM; Settimo, L1
De Jonghe, S; Herdewijn, P; Moreels, L; Peigneur, S; Rozenski, J; Tian, J; Tytgat, J; Van den Steen, PE; Vandermosten, L1
Brodie, NH; McGhie, RL; O'Hara, H; Schiff, AA; Valle-Jones, JC1
Frisk-Holmberg, M; van der Kleijn, E1
De Leenheer, A; Heyndrickx, A1
Tuomisto, J1
Agren, A; Brodin, A1
Horn, AS; Trace, RC1
Brodin, A; Nilsson, MI1
Maickel, RP; Sokol, GH1
Oates, JA; Shand, DG1
Ahonen, A; Pentilä, A1
Gross, R; Linker, H; Reuter, H1
Beierle, FA; Hubbard, RW1
Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA1
Ali, MS; Khan, AB; Khan, JM; Khan, RH1

Trials

1 trial(s) available for promazine and nortriptyline

ArticleYear
Anxiety/depression in elderly patients. A double-blind comparative study of fluphenazine/nortriptyline and promazine.
    The Practitioner, 1975, Volume: 215, Issue:1289

    Topics: Age Factors; Aged; Anxiety; Clinical Trials as Topic; Depression; Fluphenazine; Humans; Nitrazepam; Nortriptyline; Promazine; Time Factors

1975

Other Studies

23 other study(ies) available for promazine and nortriptyline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Astemizole analogues with reduced hERG inhibition as potent antimalarial compounds.
    Bioorganic & medicinal chemistry, 2017, 12-15, Volume: 25, Issue:24

    Topics: Antimalarials; Astemizole; Dose-Response Relationship, Drug; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Transcriptional Regulator ERG

2017
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:3

    Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction

1971
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine

1974
Rates of transfer of organic protolytic solutes between an aqueous and an organic phase. I. A study of the transfer dependency of pH and the absolute rate of resolvation.
    Acta pharmaceutica Suecica, 1971, Volume: 8, Issue:6

    Topics: Alprenolol; Cyclohexanes; Ephedrine; Hydrogen-Ion Concentration; Kinetics; Nortriptyline; Phenothiazines; Phenylbutazone; Procaine; Promazine; Solubility; Spectrophotometry; Water

1971
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes

1974
Rates of transfer of organic protolytic solutes between an aqueous and an organic phase. II. Rates of mass transfer between water and different organic liquids.
    Acta pharmaceutica Suecica, 1973, Volume: 10, Issue:3

    Topics: Alprenolol; Benzene; Chloroform; Cyclohexanes; Ephedrine; Hydrogen-Ion Concentration; Methods; Nortriptyline; Pentobarbital; Phenobarbital; Phenylbutazone; Promazine; Solubility; Solvents; Water

1973
Toxic interactions of d-amphetamine and tricyclic antidepressants in mice.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 3, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Antagonism; Drug Interactions; Drug Synergism; Imipramine; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nortriptyline; Promazine; Time Factors

1972
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
    Acta physiologica Scandinavica, 1971, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine

1971
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
    Thrombosis et diathesis haemorrhagica, 1969, Nov-15, Volume: 22, Issue:2

    Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine

1969
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline

1983
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity

1998
Interaction of amphiphilic drugs with human and bovine serum albumins.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97

    Topics: Adsorption; Animals; Binding Sites; Cattle; Circular Dichroism; Humans; Kinetics; Nortriptyline; Pharmaceutical Preparations; Promazine; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Surface-Active Agents

2012