proline has been researched along with vigabatrin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Sved, AF; Sved, JC | 1 |
| Ciesielski, L; Gobaille, S; Mandel, P; Molina, V | 1 |
| Sved, AF; Tsukamoto, K | 1 |
| Gayet, J; Ginefri-Gayet, M | 1 |
| Kelley, AE; Stratford, TR | 1 |
| Agulian, S; Kocsis, JD; Yee, JM | 1 |
| Abraini, JH; Bouquet, C; Cagniard, B; Kriem, B; Rostain, JC | 1 |
| An, SJ; Choi, SY; Hwang, IK; Jeong, YG; Jung, JY; Kang, TC; Kim, DW; Kwon, OS; Park, SK; Won, MH | 1 |
| Fait, A; Fromm, H; Yellin, A | 1 |
| Abbot, EL; Gatfield, KM; Grenade, DS; Kennedy, DJ; Thwaites, DT | 1 |
| Bräuner-Osborne, H; Brodie, JD; Chebib, M; Craft, CM; Dewey, SL; Gerasimov, MR; Kvist, T; Lee, H; Madsen, KK; Miller, SR; Pan, Y; Pera, E; Schiffer, WK; Schousboe, A; Silverman, RB; Wellendorph, P | 1 |
| Silverman, RB | 1 |
| Broberg, ML; Frølund, S; Holm, R; Jensen, A; Kall, MA; Nielsen, AL; Nielsen, CU | 1 |
| Holm, R; Juul, RV; Kreilgaard, M; Nielsen, CU; Nøhr, MK; Thale, ZI | 1 |
| Holm, R; Lagunas, C; Nielsen, CU; Plum, J; Rasmussen, RN | 1 |
| Crabtree, GW; Gogos, JA; Gordon, JA; Park, AJ | 1 |
17 other study(ies) available for proline and vigabatrin
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Endogenous GABA acts on GABAB receptors in nucleus tractus solitarius to increase blood pressure.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vigabatrin | 1990 |
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin | 1986 |
Enhanced gamma-aminobutyric acid-mediated responses in nucleus tractus solitarius of hypertensive rats.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Analysis of Variance; Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Neurotransmitter Agents; Nipecotic Acids; Organophosphorus Compounds; Pressoreceptors; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Sodium Chloride; Solitary Nucleus; Vigabatrin | 1993 |
Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Bicuculline; Body Temperature Regulation; Hypothermia; Infusions, Parenteral; Ketanserin; Male; Methionine Sulfoximine; Nipecotic Acids; Pindolol; Proline; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Vigabatrin | 1993 |
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
Topics: Animals; Baclofen; Eating; Enzyme Inhibitors; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Nucleus Accumbens; Proline; Rats; Rats, Sprague-Dawley; Vigabatrin | 1997 |
Vigabatrin enhances promoted release of GABA in neonatal rat optic nerve.
Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Axons; Bicuculline; Carrier Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Models, Neurological; Nipecotic Acids; Optic Nerve; Organic Anion Transporters; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Time Factors; Vigabatrin | 1998 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium; High Pressure Neurological Syndrome; Male; Motor Activity; Muscimol; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra; Synaptic Transmission; Time Factors; Vigabatrin | 1998 |
Altered GABAB receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity.
Topics: Animals; Baclofen; Blotting, Western; Cell Count; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Antagonists; Gene Expression Regulation; Gerbillinae; Hippocampus; Immunohistochemistry; Proline; Receptors, GABA-B; Vigabatrin | 2004 |
GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Arabidopsis; gamma-Aminobutyric Acid; Hydrogen Peroxide; Light; Mutation; Proline; Reactive Oxygen Species; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Vigabatrin | 2005 |
Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.
Topics: Amino Acid Transport Systems; Biological Transport; Caco-2 Cells; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Microvilli; Proline; Symporters; Vigabatrin | 2006 |
(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.
Topics: 4-Aminobutyrate Transaminase; Animals; Biological Availability; Carboxylic Acids; Cocaine-Related Disorders; Cyclopentanes; Dogs; Dopamine; Electroretinography; Female; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Humans; Male; Mice; Microdialysis; Nucleus Accumbens; Oocytes; Positron-Emission Tomography; Proline; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Retina; Stereoisomerism; Tissue Distribution; Vigabatrin; Xenopus laevis | 2012 |
The 2011 E. B. Hershberg award for important discoveries in medicinally active substances: (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Awards and Prizes; Cocaine-Related Disorders; Humans; Infant; Models, Molecular; Molecular Structure; Proline; Rats; Spasms, Infantile; Substance-Related Disorders; United States; Vigabatrin | 2012 |
Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.
Topics: Absorption; Administration, Rectal; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Biological Availability; Biological Transport; Caco-2 Cells; Epithelium; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Oocytes; Proline; Protons; Rats; Rats, Sprague-Dawley; Rectum; Symporters; Tryptophan; Vigabatrin; Xenopus laevis | 2012 |
Is oral absorption of vigabatrin carrier-mediated?
Topics: Administration, Oral; Amino Acid Transport Systems, Neutral; Animals; Biological Availability; Dose-Response Relationship, Drug; Intestinal Absorption; Male; Models, Biological; Proline; Rats, Sprague-Dawley; Sarcosine; Symporters; Tryptophan; Vigabatrin | 2015 |
Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated Caco-2, LLC-PK1 and rat renal SKPT cells.
Topics: Aminolevulinic Acid; Animals; beta-Alanine; Caco-2 Cells; Cell Line; gamma-Aminobutyric Acid; Humans; Isoxazoles; Kidney; LLC-PK1 Cells; Membrane Glycoproteins; Membrane Transport Proteins; Nicotinic Acids; Nipecotic Acids; Osmolar Concentration; Osmosis; Proline; Rats; RNA, Messenger; Swine; Taurine; Vigabatrin | 2016 |
Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade.
Topics: Animals; Central Nervous System; Cytosol; Disease Models, Animal; Gamma Rhythm; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamate Decarboxylase; Humans; Mice; Proline; Proline Oxidase; Schizophrenia; Vigabatrin | 2016 |