proline and vigabatrin

proline has been researched along with vigabatrin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's6 (35.29)18.2507
2000's4 (23.53)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Sved, AF; Sved, JC1
Ciesielski, L; Gobaille, S; Mandel, P; Molina, V1
Sved, AF; Tsukamoto, K1
Gayet, J; Ginefri-Gayet, M1
Kelley, AE; Stratford, TR1
Agulian, S; Kocsis, JD; Yee, JM1
Abraini, JH; Bouquet, C; Cagniard, B; Kriem, B; Rostain, JC1
An, SJ; Choi, SY; Hwang, IK; Jeong, YG; Jung, JY; Kang, TC; Kim, DW; Kwon, OS; Park, SK; Won, MH1
Fait, A; Fromm, H; Yellin, A1
Abbot, EL; Gatfield, KM; Grenade, DS; Kennedy, DJ; Thwaites, DT1
Bräuner-Osborne, H; Brodie, JD; Chebib, M; Craft, CM; Dewey, SL; Gerasimov, MR; Kvist, T; Lee, H; Madsen, KK; Miller, SR; Pan, Y; Pera, E; Schiffer, WK; Schousboe, A; Silverman, RB; Wellendorph, P1
Silverman, RB1
Broberg, ML; Frølund, S; Holm, R; Jensen, A; Kall, MA; Nielsen, AL; Nielsen, CU1
Holm, R; Juul, RV; Kreilgaard, M; Nielsen, CU; Nøhr, MK; Thale, ZI1
Holm, R; Lagunas, C; Nielsen, CU; Plum, J; Rasmussen, RN1
Crabtree, GW; Gogos, JA; Gordon, JA; Park, AJ1

Other Studies

17 other study(ies) available for proline and vigabatrin

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Endogenous GABA acts on GABAB receptors in nucleus tractus solitarius to increase blood pressure.
    Brain research, 1990, Sep-03, Volume: 526, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vigabatrin

1990
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin

1986
Enhanced gamma-aminobutyric acid-mediated responses in nucleus tractus solitarius of hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Analysis of Variance; Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Neurotransmitter Agents; Nipecotic Acids; Organophosphorus Compounds; Pressoreceptors; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Sodium Chloride; Solitary Nucleus; Vigabatrin

1993
Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Bicuculline; Body Temperature Regulation; Hypothermia; Infusions, Parenteral; Ketanserin; Male; Methionine Sulfoximine; Nipecotic Acids; Pindolol; Proline; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Vigabatrin

1993
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-01, Volume: 17, Issue:11

    Topics: Animals; Baclofen; Eating; Enzyme Inhibitors; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Nucleus Accumbens; Proline; Rats; Rats, Sprague-Dawley; Vigabatrin

1997
Vigabatrin enhances promoted release of GABA in neonatal rat optic nerve.
    Epilepsy research, 1998, Volume: 29, Issue:3

    Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Axons; Bicuculline; Carrier Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Models, Neurological; Nipecotic Acids; Optic Nerve; Organic Anion Transporters; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Time Factors; Vigabatrin

1998
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
    Neuroreport, 1998, May-11, Volume: 9, Issue:7

    Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium; High Pressure Neurological Syndrome; Male; Motor Activity; Muscimol; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra; Synaptic Transmission; Time Factors; Vigabatrin

1998
Altered GABAB receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity.
    Neuroscience research, 2004, Volume: 49, Issue:4

    Topics: Animals; Baclofen; Blotting, Western; Cell Count; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Antagonists; Gene Expression Regulation; Gerbillinae; Hippocampus; Immunohistochemistry; Proline; Receptors, GABA-B; Vigabatrin

2004
GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants.
    FEBS letters, 2005, Jan-17, Volume: 579, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Arabidopsis; gamma-Aminobutyric Acid; Hydrogen Peroxide; Light; Mutation; Proline; Reactive Oxygen Species; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Vigabatrin

2005
Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.
    British journal of pharmacology, 2006, Volume: 147, Issue:3

    Topics: Amino Acid Transport Systems; Biological Transport; Caco-2 Cells; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Microvilli; Proline; Symporters; Vigabatrin

2006
(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Biological Availability; Carboxylic Acids; Cocaine-Related Disorders; Cyclopentanes; Dogs; Dopamine; Electroretinography; Female; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Humans; Male; Mice; Microdialysis; Nucleus Accumbens; Oocytes; Positron-Emission Tomography; Proline; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Retina; Stereoisomerism; Tissue Distribution; Vigabatrin; Xenopus laevis

2012
The 2011 E. B. Hershberg award for important discoveries in medicinally active substances: (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms.
    Journal of medicinal chemistry, 2012, Jan-26, Volume: 55, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Awards and Prizes; Cocaine-Related Disorders; Humans; Infant; Models, Molecular; Molecular Structure; Proline; Rats; Spasms, Infantile; Substance-Related Disorders; United States; Vigabatrin

2012
Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.
    Pharmaceutical research, 2012, Volume: 29, Issue:4

    Topics: Absorption; Administration, Rectal; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Biological Availability; Biological Transport; Caco-2 Cells; Epithelium; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Oocytes; Proline; Protons; Rats; Rats, Sprague-Dawley; Rectum; Symporters; Tryptophan; Vigabatrin; Xenopus laevis

2012
Is oral absorption of vigabatrin carrier-mediated?
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Mar-10, Volume: 69

    Topics: Administration, Oral; Amino Acid Transport Systems, Neutral; Animals; Biological Availability; Dose-Response Relationship, Drug; Intestinal Absorption; Male; Models, Biological; Proline; Rats, Sprague-Dawley; Sarcosine; Symporters; Tryptophan; Vigabatrin

2015
Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated Caco-2, LLC-PK1 and rat renal SKPT cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Jan-20, Volume: 82

    Topics: Aminolevulinic Acid; Animals; beta-Alanine; Caco-2 Cells; Cell Line; gamma-Aminobutyric Acid; Humans; Isoxazoles; Kidney; LLC-PK1 Cells; Membrane Glycoproteins; Membrane Transport Proteins; Nicotinic Acids; Nipecotic Acids; Osmolar Concentration; Osmosis; Proline; Rats; RNA, Messenger; Swine; Taurine; Vigabatrin

2016
Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade.
    Cell reports, 2016, 10-04, Volume: 17, Issue:2

    Topics: Animals; Central Nervous System; Cytosol; Disease Models, Animal; Gamma Rhythm; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamate Decarboxylase; Humans; Mice; Proline; Proline Oxidase; Schizophrenia; Vigabatrin

2016