proline has been researched along with urea in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 74 (40.66) | 18.7374 |
| 1990's | 24 (13.19) | 18.2507 |
| 2000's | 36 (19.78) | 29.6817 |
| 2010's | 40 (21.98) | 24.3611 |
| 2020's | 8 (4.40) | 2.80 |
| Authors | Studies |
|---|---|
| Kurelec, B | 1 |
| Gimpel, JA; Hensgens, HE; Meijer, AJ; Tager, JM; Williamson, JR | 1 |
| Fischl, M; Orlowski, RC; Walter, R; Yoshimoto, T | 1 |
| fox, JL; Kapp, R; Stevens, SE | 1 |
| Jagenburg, R; Jonsson, O; Lundholm, K; Lundstam, S; Nauclér, J; Pettersson, S; Scherstén, T | 1 |
| Cooper, TG; Sumrada, R | 1 |
| Jaenicke, R; Risse, B; Rudolph, R; Schumacher, G; Stempfer, G | 1 |
| Chaffotte, A; Lascu, I; Limbourg-Bouchon, B; Véron, M | 1 |
| Hahn, U; Kiefhaber, T; Quaas, R; Schmid, FX | 1 |
| Koshy, TI; Luntz, TL; Margoliash, E; Schejter, A | 1 |
| Andre, NM; Kilroe-Smith, TA; Krengel, B | 1 |
| Cooper, TG; Genbauffe, F; Lea, HZ; Rai, R | 1 |
| Baker, DH; Edmonds, MS; Lowry, KR | 1 |
| Chambers, S; Kunin, CM | 1 |
| Rogers, QR; Visek, WJ | 1 |
| Drake, AF; Shewry, PR; Tatham, AS | 1 |
| Baugh, S; Davis, EJ | 1 |
| Doyle, FH; Foster, GV; Kalu, DN; Pennock, J | 1 |
| Dadd, RH | 1 |
| Bornstein, P; Ehrlich, HP; Monson, JM; Von der Mark, K; Wyke, AW | 1 |
| Cornick, LR; Cutler, RW; Hammerstad, JP; Murray, JE | 1 |
| Cutler, RW; Hammerstad, JP; Murray, JE | 1 |
| Hellebust, JA; Liu, MS | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Fessler, JH; Fessler, LI | 1 |
| Frimpter, GW | 1 |
| Toyoda, M; Yamauchi, K | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Erdös, EG; Kakimoto, T; Oshima, G; Yeh, HS | 1 |
| Austic, RE | 1 |
| Aalto, M; Kulonen, E; Lampiaho, K; Pikkarainen, J | 1 |
| Gross, J; Linsenmayer, TF; Trelstad, RL | 1 |
| Allen, NK; Baker, DH | 1 |
| Alvino, CG; Ingram, VM; Remington, L | 1 |
| Holden, JT; Wilson, OH | 1 |
| Vinnars, E | 1 |
| Dolif, D; Jürgens, P | 1 |
| Blair, R; Lee, DJ | 1 |
| Handler-Bernich, E; Lotke, P; Rubenstein, R | 1 |
| Oltjen, RR; Slyter, LL; Williams, EE; Wilson, RL | 1 |
| Martin, GR; McGoodwin, E; Müller, PK | 1 |
| Gold, MB; Reynold, JM; Scriver, CR | 1 |
| Woods, EF | 1 |
| Gordon, WG; Groves, ML | 1 |
| Fuchs, G; Oepen, H; Oepen, I | 1 |
| Dietz, RW; Flipse, RJ | 1 |
| Lukens, LN | 1 |
| Davis, RH; Lawless, MB; Port, LA | 1 |
| Fürst, P; Hallgren, B; Hermansson, IL; Josephson, B; Vinnars, E | 1 |
| Katsura, I; Noda, H | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Dintzis, HM; McMenamy, RH; Watson, F | 1 |
| Kloss, G; Schwarz, E | 1 |
| Brunet, G; Metz, R; Salter, JM | 1 |
| Brown, HH | 1 |
| Gulyĭ, MF; Kokunin, VA; Litvinenko, LT; Martynenko, FP | 1 |
| Shimura, K; Yokotsuka, K; Yoshida, M | 1 |
| Hosken, R; Sleigh, R; Smith, MB; Thompson, EO | 1 |
| Horie, Y; Inokuchi, T; Ito, T | 1 |
| Tagari, H | 1 |
| Bock, RM; Cherayil, JD | 1 |
| Herskovits, TT | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Estes, FL; Wetzel, RL | 1 |
| McGivan, JD; Staddon, JM | 1 |
| Breckenridge, AM; Park, BK; Yeung, JH | 1 |
| Cianciosi, SC; Hird, FJ; McLean, RM; Niekrash, RE | 1 |
| Boackle, RJ; Bonewald, L; Vesely, J; Wang, AC | 1 |
| Meister, A; Wellner, D | 1 |
| Brandts, JF; Lin, LN | 2 |
| Ishiguro, I; Matsuzawa, T; Sugimoto, N | 1 |
| Hensgens, HE; Meijer, AJ | 1 |
| Gopalakrishna, R; Nagarajan, B | 1 |
| Coudray-Lucas, C; Cynober, L; De Bandt, JP; Giboudeau, J; Lim, SK; Poupon, R | 1 |
| Buhler, JM; Ripoche, P; Rousselet, G; Simon, M | 1 |
| Hartman, WJ; Prior, RL; Torre, PM | 1 |
| Mücke, M; Schmid, FX | 1 |
| Hamada, S; Moriyama, Y; Takeda, K; Yamaguchi, K | 1 |
| Huq, F; Ruell, P; Thompson, M | 1 |
| Horowitz, PM; Luo, GX | 1 |
| Komatsubara, S; Masuda, M; Nishimura, N; Takamatu, S; Tosa, T | 1 |
| Fersht, AR; Schreiber, G | 1 |
| Bode, AM; Nordlie, RC | 1 |
| Deville-Bonne, D; Glaser, P; Lascu, I; Véron, M | 1 |
| Chambers, ST; Peddie, BA | 1 |
| Hampl, H; Nündel, M; Riedel, E; Steudle, V | 1 |
| Arnoys, EJ; Blankespoor, S; Born, T; Everman, R; Gray, TM; Jagar, R; Plowman, D; Stair, A; Zhang, D | 1 |
| Flynn, NE; Wu, G | 1 |
| Bernhardt, R; Bonomi, F; Iametti, S; Uhlmann, H; Vecchio, G | 1 |
| Bhattacharyya, D; Dutta, S; Maity, NR | 1 |
| Camacho Barrón, M; González de Mejía, E | 1 |
| Fersht, AR; Guralnick, BJ; Itzhaki, LS; Tang, KS; Wang, WK | 1 |
| Capaldi, AP; Ferguson, SJ; Radford, SE | 1 |
| Flores, E; Herrero, A; Muro-Pastor, AM; Quintero, MJ | 1 |
| Hayano, T; Ikura, T; Kuwajima, K; Takahashi, N | 1 |
| Clemmesen, JO; Kondrup, J; Ott, P | 1 |
| Eastman, P; Fink, AL; Nishimura, C; Riley, R | 1 |
| Itzhaki, LS; Rousseau, F; Schymkowitz, JW | 1 |
| Eyles, SJ; Gierasch, LM | 1 |
| Chiti, F; Dobson, CM; Hamada, D; Pertinhez, TA; Smith, LJ; Stefani, M; Taddei, N | 1 |
| Gutierrez-Cruz, G; Van Heerden, AH; Wang, K | 1 |
| Dobson, CM; Ferguson, SJ; Radford, SE; Reader, JS; Thompson, GS; Van Nuland, NA | 1 |
| Diamant, S; Eliahu, N; Goloubinoff, P; Rosenthal, D | 1 |
| Natesan, S; Reddy, SR | 1 |
| Hollien, J; Marqusee, S | 1 |
| Matthews, CR; Wu, Y | 2 |
| Mossing, MC; Satumba, WJ | 1 |
| Burke, J; Dirr, HW; Nathaniel, C; Wallace, LA | 1 |
| Ma, K; Wang, K | 1 |
| HARRINGTON, H; SAKAMI, W | 1 |
| CASSIDY, JE; LOWERY, JA | 1 |
| AMSTEY, M; BROWN, O; MCCARTY, KS; WOODSON, B | 1 |
| SENFT, AW | 1 |
| Bacchawat, K; Lingaraju, GM; Prajapati, RS; Surolia, A; Varadarajan, R | 1 |
| Bon, EP; Ferrara, MA; Mattoso, JM; Pereira, N | 1 |
| Burns-Hamuro, LL; Dalessio, PM; Ropson, IJ | 1 |
| Bann, JG; Frieden, C | 1 |
| Ball, RO; Pencharz, PB; Shoveller, AK; Urschel, KL | 1 |
| Barrick, D; Bradley, CM; Mello, CC; Tripp, KW | 1 |
| Boswell, S; Colón, W; Meinhold, D | 1 |
| Baker, S; Matsuka, YV; Nunez, L; Severina, E | 1 |
| Itzhaki, LS; Lowe, AR | 1 |
| Frieden, C; Li, H | 1 |
| Draper, DE; Lambert, D | 1 |
| Butkiewicz, N; Chen, KX; Cheng, KC; Liu, R; Njoroge, FG; Pichardo, J; Vibulbhan, B; Yang, W | 1 |
| Doyle, AG; Jacobsen, EN | 1 |
| Funck, D; Koch, W; Stadelhofer, B | 1 |
| Bart Williams, D; Hu, CA; Khalil, S; Valle, D; Wan, G; Zhaorigetu, S | 1 |
| Castillo, L; Roth, RM; Tharakan, JF; Young, VR; Yu, YM; Zurakowski, D | 1 |
| Hasserodt, J; Waibel, M | 1 |
| Antonov, D; Ayesa, S; Classon, B; de Kock, H; Delouvroy, F; Edlund, M; Eneroth, A; Hu, L; Ivanov, V; Johansson, PO; Kahnberg, P; Kindermans, N; Lenz, O; Lin, TI; Lindström, S; McGowan, D; Nilsson, M; Raboisson, P; Rosenquist, A; Samuelsson, B; Simmen, K; Surleraux, D; Tahri, A; Van de Vreken, W; Van Dooren, M; Vendeville, S; Vrang, L; Wigerinck, P; Wikstrom, K | 1 |
| Bogdan, AR; Mason, BP; McQuade, DT; Opalka, SM; Poe, SL; Steinbacher, JL | 1 |
| Arasappan, A; Bennett, F; Chase, R; Feld, B; Guo, Z; Hart, A; Madison, V; Malcolm, B; Njoroge, FG; Pichardo, J; Prongay, A; Ralston, R; Skelton, A; Tong, X; Xia, E; Zhang, R | 1 |
| Bader, R; Blank, M; Borchard, PM; Cauffman, SR; Felch, KL; Griffin, RG; Maas, WE; Pawsey, S; Rosay, M; Schauwecker, R; Temkin, RJ; Tometich, L; Weber, RT | 1 |
| Held, C; Neuhaus, T; Sadowski, G | 1 |
| Ding, H; Liang, F; Lin, S; Liu, J; Wei, Y; Zhao, B | 1 |
| Clement, RP; Cunliffe, JM; Dreyer, DP; Hayes, RN; Shen, JX | 1 |
| Bergmann, JF; de Bruijne, J; de Knegt, RJ; Hughes, EA; Janssen, HL; Li, J; Molenkamp, R; Reesink, HW; Schinkel, J; Tong, X; Treitel, MA; van Lier, JJ; van Vliet, AA; Weegink, CJ | 1 |
| Alton, KB; Chowdhury, SK; Ghosal, A; Gu, C; Kishnani, NS; Su, AD; Tong, W; Yuan, Y | 1 |
| Clement, RP; Cunliffe, JM; Dreyer, DP; Hayes, RN; Shen, JX; Wei, X | 1 |
| Arjomand, A; Chowdhury, SK; Gao, L; Hesk, D; Kasserra, C; Li, J; Song, Q | 1 |
| Jeon, A; Kim, H; Lee, HS; Medda, AK; Park, CM; Sohn, JH | 1 |
| Ben-Shimon, A; Gilon, C; Hazan, C; Hurevich, M; Klein, S; Levitzki, A; Niv, MY; Rosenthal, D; Shalev, DE; Tal-Gan, Y | 1 |
| Auton, M; Bolen, DW; Holthauzen, LM; Rösgen, J; Sinev, M | 1 |
| Hou, T; Li, Y; Mao, X; Yu, H; Zhang, L; Zhu, J | 1 |
| Imaoka, T; Iura, Y; Kubota, H; Morihira, K; Morokata, T; Nitta, A; Ohta, M; Sato, I; Takahashi, T; Takeuchi, M; Tomioka, H; Tsukamoto, S | 1 |
| Hollenstein, M | 1 |
| Bush, DR; Scaraffia, PY; Wysocki, VH | 1 |
| Gowda, DC; Shantharam, CS; Sridhara, MB; Suhas, R; Suyoga Vardhan, DM | 1 |
| Boonstra, A; de Bruijne, J; de Knegt, RJ; Hotho, DM; Janssen, HL; Reesink, HW; Spaan, M; Treitel, MA | 1 |
| Capp, MW; Diehl, RC; Guinn, EJ; Record, MT; Tsodikov, OV | 1 |
| Bergmann, JF; de Bruijne, J; de Knegt, RJ; Hughes, E; Janssen, HL; Molenkamp, R; Rebers, SP; Reesink, HW; Schinkel, J; Thomas, XV; Treitel, MA; Weegink, CJ | 1 |
| Myers, JK; Silvers, TR | 1 |
| Fremaux, J; Guichard, G; Kauffmann, B | 1 |
| Porwański, S | 1 |
| Garde-Cerdán, T; González-Arenzana, L; López, R; López-Alfaro, I; Portu, J; Santamaría, P | 1 |
| Burke, T; Coumoundouros, C; Culham, DE; Deutch, CE; Ellinger, J; Kerr, CH; Murdock, L; Plater, SM; To, E; Wood, JM; Wright, G | 1 |
| Chen, BZ; Geng, L; Ji, M; Wang, H | 1 |
| Almeida, LM; Almeida, Mdo C; Barros, AS; Carreira, IM; Domingues, MR; Duarte, D; Galhano, E; Gil, AM; Martins, AS; Pinto, J; Pita, C | 1 |
| Clayden, J; Maury, J | 1 |
| Chen, J; Du, G; Zhao, X; Zhou, J; Zou, H | 1 |
| Hermansen, JR; Jas, GS; Johnson, CK; Kuczera, K; Middaugh, CR; Rentchler, EC; Słowicka, AM | 1 |
| Ingole, TS; Kale, SS; Sanjayan, GJ; Santhosh Babu, S | 1 |
| Choi, HW; Koh, WP; Lu, Y; Ong, CN; Pan, A; Subramaniam, T; Wang, Y; Yuan, JM | 1 |
| Aichholz, R; Blanz, J; Blasco, F; Caravatti, G; Fairhurst, RA; Fritsch, C; Guagnano, V; Maira, SM; Schnell, C; Seiler, FH; Wipfli, P | 1 |
| Aurich, C; Budik, S; De Oliveira, RA | 1 |
| Miyazaki, T; Oyoshi, T; Yagi, R | 1 |
| Harder, K; Hildebrandt, JP; Müller, C; Wiesenthal, AA | 1 |
| Blume, C; Laxa, M; Mühlenbruch, M; Ost, J; Peterhänsel, C | 1 |
| Besio, R; Forlino, A; Tonelli, F | 1 |
| Chilkoti, A; Dzuricky, M; Garcia Quiroz, F; Li, NK; Roberts, S; Weber, P; Weitzhandler, I; Yingling, YG | 1 |
| Bazer, FW; Cleere, JJ; Gilbreath, KR; Satterfield, MC; Wu, G | 1 |
| Demizu, Y; Misawa, T; Yokoo, H | 1 |
| Batskikh, SN; Burnevich, EZ; Chulanov, VP; Gusev, DA; Kizlo, SN; Klimova, EA; Krasavina, EN; Mamonova, NA; Samsonov, MY; Tarkhova, EP; Yushchuk, ND; Znoyko, OO | 1 |
| Bai, Y; Feng, Y; Fu, L; Gao, GF; Liao, H; Qi, J; Shi, Y; Song, H; Tan, W; Ye, F | 1 |
| Childs, EW; Jas, GS; Kuczera, K; Middaugh, CR | 1 |
| Zondlo, NJ | 1 |
| Khan, A; Nayeem, SM | 1 |
| Bartosch, B; Fedorov, VS; Golikov, MV; Ivanov, AV; Ivanova, ON; Kochetkov, SN; Krasnov, GS; Kudryavtseva, AV; Snezhkina, AV; Valuev-Elliston, VT; Zakirova, NF | 1 |
| Akbari, V; Bijari, N; Karima, S; Khodarahmi, R; Mehrabi, M; Ojaghi, S; Ranjbar, S; Sankian, M | 1 |
6 review(s) available for proline and urea
| Article | Year |
|---|---|
Insect nutrition: current developments and metabolic implications.
Topics: Amino Acids; Animals; Aphids; Ascorbic Acid; Choline; Coleoptera; Cystine; DNA; Drosophila melanogaster; Fatty Acids; Folic Acid; Glycine; Insecta; Lepidoptera; Methionine; Minerals; Nutritional Physiological Phenomena; Proline; RNA; Sterols; Tyrosine; Urea; Vitamin B 12; Vitamin E | 1973 |
Aminoacidurias due to inherited disorders of metabolism. 2.
Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline; Dipeptides; Glutarates; Glycine; Histidine; Humans; Hydroxyproline; Hyperglycemia; Infant, Newborn; Keto Acids; Lysine; Malonates; Maple Syrup Urine Disease; Ornithine Carbamoyltransferase; Phosphotransferases; Proline; Sarcosine; Succinates; Urea; Valine | 1973 |
A survey of inborn errors of amino acid metabolism and transport in man.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Branched-Chain; Biological Transport; Cystinosis; Female; Glutathione; Glycine; Homocystinuria; Humans; Hydroxyproline; Infant; Infant, Newborn; Lysine; Maple Syrup Urine Disease; Phenylalanine; Proline; Serine; Tyrosine; Urea; Valine | 1981 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
Small-molecule H-bond donors in asymmetric catalysis.
Topics: Aldehydes; Alkenes; Catalysis; Hydrogen Bonding; Imines; Ketones; Molecular Structure; Proline; Urea | 2007 |
De Novo Design of Cell-Penetrating Foldamers.
Topics: Amino Acids; Cell-Penetrating Peptides; Drug Carriers; Humans; Peptides, Cyclic; Peptoids; Proline; Urea | 2020 |
7 trial(s) available for proline and urea
| Article | Year |
|---|---|
Calcium alpha-ketoglutarate administration to malnourished hemodialysis patients improves plasma arginine concentrations.
Topics: Adult; Aged; Arginine; Female; Follow-Up Studies; Glutamic Acid; Histidine; Humans; Ketoglutaric Acids; Kidney Failure, Chronic; Male; Middle Aged; Nutrition Disorders; Phosphates; Proline; Reference Values; Renal Dialysis; Time Factors; Urea | 1996 |
Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet.
Topics: Adult; Analysis of Variance; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Diet; Dietary Proteins; Female; Glutamic Acid; Homeostasis; Humans; Infusions, Intravenous; Isotope Labeling; Kinetics; Leucine; Male; Nitrogen Isotopes; Oxidation-Reduction; Proline; Time Factors; Urea | 2008 |
Antiviral activity of narlaprevir combined with ritonavir and pegylated interferon in chronic hepatitis C patients.
Topics: Adult; Aged; Antiviral Agents; Cyclopropanes; Dipeptides; Drug Administration Schedule; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Inpatients; Interferon alpha-2; Interferon-alpha; Leucine; Male; Middle Aged; Outpatients; Polyethylene Glycols; Proline; Recombinant Proteins; Recurrence; Ritonavir; RNA, Viral; Sulfones; Urea; Young Adult | 2010 |
Sustained virologic response after therapy with the HCV protease inhibitor narlaprevir in combination with peginterferon and ribavirin is durable through long-term follow-up.
Topics: Adult; Aged; Antiviral Agents; Cyclopropanes; Dipeptides; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Leucine; Male; Middle Aged; Placebos; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; RNA, Viral; Sulfones; Treatment Outcome; Urea; Viral Load | 2013 |
Evolutionary dynamics of hepatitis C virus NS3 protease domain during and following treatment with narlaprevir, a potent NS3 protease inhibitor.
Topics: Adult; Antiviral Agents; Cyclopropanes; Dipeptides; Drug Therapy, Combination; Evolution, Molecular; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Leucine; Longitudinal Studies; Male; Middle Aged; Polyethylene Glycols; Proline; Protease Inhibitors; Recombinant Proteins; Ribavirin; Sequence Analysis, DNA; Sulfones; Urea; Viral Load; Viral Nonstructural Proteins | 2013 |
Ruminal microbes of adult sheep do not degrade extracellular l-citrulline.
Topics: Ammonia; Animal Feed; Animals; Arginine; Bacteria; Citrulline; Diet; Dietary Supplements; Female; Glutamic Acid; Glutamine; Ornithine; Proline; Rumen; Sheep; Urea | 2020 |
[Efficacy and safety of narlaprevir/ritonavir and daclatasvir non interferon combination in population of Russian patients with chronic hepatitis C].
Topics: Adult; Antiviral Agents; Carbamates; Cyclopropanes; Dipeptides; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Leucine; Middle Aged; Proline; Pyrrolidines; Ritonavir; Russia; Sulfones; Treatment Outcome; Urea; Valine | 2019 |
169 other study(ies) available for proline and urea
| Article | Year |
|---|---|
Catabolic path of arginine and NAD regeneration in the parasite Fasciola hepatica.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Radioisotopes; Carboxylic Acids; Cytosol; Dogs; Fasciola hepatica; Glutamates; Ketoglutaric Acids; Mitochondria; NAD; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Pyruvates; Urea | 1975 |
Prolone metabolism in isolated rat liver cells.
Topics: Animals; Aspartic Acid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Ethanol; Glucose; Glutamates; In Vitro Techniques; Lactates; Liver; Mitochondria, Liver; Picolinic Acids; Proline; Rats; Sulfhydryl Compounds; Urea | 1978 |
Post-proline cleaving enzyme and post-proline dipeptidyl aminopeptidase. Comparison of two peptidases with high specificity for proline residues.
Topics: Aminopeptidases; Endopeptidases; Kinetics; Proline; Substrate Specificity; Urea | 1978 |
A survey of available nitrogen sources for growth of the blue-green alga, Agmenellum quadruplicatum.
Topics: Amino Acids; Ammonium Chloride; Cyanobacteria; Nitrates; Nitrites; Nitrogen; Proline; Purines; Urea | 1975 |
Metabolism in the hypothermically perfused dog kidney. Utilization and production of amino acids.
Topics: Alanine; Amino Acids; Ammonia; Animals; Dogs; Fatty Acids; Gluconeogenesis; Glucose; Glutamates; Glutamine; Glycine; Hypothermia, Induced; Kidney; Lactates; Nitrogen; Organ Preservation; Perfusion; Proline; Urea | 1977 |
Urea transport in Saccharomyces cerevisiae.
Topics: Ammonia; Arginine; Arsenates; Aspartic Acid; Biological Transport, Active; Cyanides; Depression, Chemical; Dinitrophenols; Energy Metabolism; Fluorides; Hydrolases; Ligases; Mutation; Proline; Saccharomyces cerevisiae; Urea; Uric Acid | 1975 |
Characterization of the stabilizing effect of point mutations of pyruvate oxidase from Lactobacillus plantarum: protection of the native state by modulating coenzyme binding and subunit interaction.
Topics: Alanine; Amino Acid Sequence; Asparagine; Enzyme Stability; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Pyruvate Oxidase; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Thiamine Pyrophosphate; Urea; Valine | 1992 |
A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation killer of prune) affects stability but not catalytic efficiency of the enzyme.
Topics: Amino Acids; Animals; Catalysis; Chromatography, Gel; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Enzyme Stability; Insect Hormones; Isoelectric Focusing; Kinetics; Mutation; Nucleoside-Diphosphate Kinase; Proline; Protein Denaturation; Serine; Spectrometry, Fluorescence; Temperature; Urea | 1992 |
Folding of ribonuclease T1. 1. Existence of multiple unfolded states created by proline isomerization.
Topics: Endoribonucleases; Escherichia coli; Genes, Synthetic; Guanidine; Guanidines; Isomerism; Kinetics; Proline; Protein Conformation; Recombinant Proteins; Ribonuclease T1; Urea | 1990 |
Changing the invariant proline-30 of rat and Drosophila melanogaster cytochromes c to alanine or valine destabilizes the heme crevice more than the overall conformation.
Topics: Alanine; Animals; Binding Sites; Cloning, Molecular; Cytochrome c Group; Drosophila melanogaster; Heme; Hot Temperature; Proline; Protein Conformation; Rats; Recombinant Proteins; Spectrum Analysis; Structure-Activity Relationship; Urea; Valine | 1990 |
Elevated glutamic acid values in a malnourished patient. A case report.
Topics: Ammonia; Aspartic Acid; Ethanolamines; Female; Glutamates; Glutamic Acid; Humans; Middle Aged; Nutrition Disorders; Pellagra; Proline; Urea | 1987 |
Transcriptional regulation of the DAL5 gene in Saccharomyces cerevisiae.
Topics: Allantoin; Biological Transport, Active; Gene Expression Regulation; Genes, Fungal; Genetic Complementation Test; Oxamic Acid; Proline; RNA, Fungal; RNA, Messenger; Saccharomyces cerevisiae; Transcription, Genetic; Urea | 1987 |
Urea cycle metabolism: effects of supplemental ornithine or citrulline on performance, tissue amino acid concentrations and enzymatic activity in young pigs fed arginine-deficient diets.
Topics: Animals; Arginase; Arginine; Body Weight; Brain; Citrulline; Intestinal Mucosa; Kidney; Liver; Male; Muscles; Ornithine; Ornithine Carbamoyltransferase; Proline; Swine; Urea | 1987 |
The osmoprotective properties of urine for bacteria: the protective effect of betaine and human urine against low pH and high concentrations of electrolytes, sugars, and urea.
Topics: Anti-Bacterial Agents; Betaine; Carbohydrates; Choline; Culture Media; Electrolytes; Enterobacter; Escherichia coli; Humans; Hydrogen-Ion Concentration; Klebsiella; Lactams; Male; Microbial Sensitivity Tests; Osmolar Concentration; Proline; Serratia; Sodium Chloride; Urea; Urine | 1985 |
Metabolic role of urea cycle intermediates: nutritional and clinical aspects. Introduction.
Topics: Ammonia; Animals; Arginine; Body Weight; Citrulline; Intestine, Small; Kidney; Liver; Nutritional Physiological Phenomena; Ornithine; Proline; Rats; Urea | 1985 |
A conformational study of a glutamine- and proline-rich cereal seed protein, C hordein.
Topics: Amino Acid Sequence; Circular Dichroism; Ethanol; Glutamine; Glutens; Hordeum; Plant Proteins; Proline; Protein Conformation; Seeds; Urea | 1985 |
Interference by ethanol of coupling between gluconeogenesis and ureagenesis from proline in isolated hepatocytes.
Topics: Animals; Ethanol; Gluconeogenesis; In Vitro Techniques; Kinetics; Liver; Male; Picolinic Acids; Proline; Rats; Rats, Inbred Strains; Urea | 1985 |
Parathyroid hormone and experimental osteosclerosis.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Femur; Kidney; Male; Osteogenesis; Osteosclerosis; Parathyroid Glands; Parathyroid Hormone; Peptides; Phosphates; Proline; Radiography; Rats; Thyroidectomy; Tritium; Urea | 1970 |
Characterization of the pro- 1 chain of procollagen.
Topics: Amino Acids; Animals; Bone and Bones; Chick Embryo; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Culture Techniques; Cysteine; Electrophoresis; Isotope Labeling; Macromolecular Substances; Microbial Collagenase; Molecular Weight; Proline; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Sulfur Isotopes; Tritium; Urea | 1972 |
Efflux of amino acid neurotransmitters from rat spinal cord slices. I. Factors influencing the sponatenous efflux of ( 14 C)glycine and 3 H-GABA.
Topics: Aminobutyrates; Animals; Biological Transport, Active; Carbon Isotopes; Cell Membrane Permeability; Cyanides; Glycine; Inulin; Lysine; Male; Neurotransmitter Agents; Ouabain; Proline; Rats; Spinal Cord; Sucrose; Taurine; Tritium; Urea | 1971 |
Efflux of amino acid neurotransmitters from rat spinal cord slices. II. Factors influencing the electrically induced efflux of ( 14 C)glycine and 3 H-GABA.
Topics: Aminobutyrates; Animals; Biological Transport, Active; Carbon Isotopes; Cerebellum; Cerebral Cortex; Cyanides; Electric Stimulation; Glutamates; Glycine; Lysine; Neurotransmitter Agents; Ouabain; Potassium; Proline; Rats; Sodium; Spinal Cord; Strychnine; Taurine; Tritium; Urea | 1971 |
Utilization of amino acids as nitrogen sources, and their effects on nitrate reductase in the marine diatom Cyclotella cryptica.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Asparagine; Cell-Free System; Chlorophyll; Eukaryota; Glutamates; Glutamine; Glycine; Isoleucine; Nitrate Reductases; Nitrates; Ornithine; Plant Proteins; Proline; Seawater; Urea; Water Microbiology | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Protein assembly of procollagen and effects of hydroxylation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Body Temperature; Bone and Bones; Carbon Radioisotopes; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chick Embryo; Chromatography, Ion Exchange; Collagen; Disulfides; Macromolecular Substances; Mathematics; Mixed Function Oxygenases; Oxidation-Reduction; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Protein Precursors; Pyridines; Temperature; Tritium; Urea | 1974 |
Conformation and some properties of -casein-like fraction of human casein.
Topics: Acrylamides; Animals; Caseins; Cattle; Chromatography, Gel; Circular Dichroism; Edetic Acid; Electrophoresis; Female; Guanidines; Humans; Macromolecular Substances; Milk, Human; Molecular Weight; Optical Rotatory Dispersion; Peptides; Pregnancy; Proline; Protein Conformation; Species Specificity; Temperature; Ultracentrifugation; Urea; Viscosity | 1972 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
Purification of lysosomal prolycarboxypeptidase angiotensinase C.
Topics: Ammonium Sulfate; Animals; Carboxypeptidases; Cathepsins; Chromatography; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Disc; Hot Temperature; Kidney; Kidney Cortex; Kinetics; Lysosomes; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Proline; Sodium Dodecyl Sulfate; Swine; Urea | 1973 |
Conversion of arginine to proline in the chick.
Topics: Amino Acids; Aminoisobutyric Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Composition; Body Weight; Carbon Isotopes; Chickens; Deficiency Diseases; Glutamates; Ornithine; Proline; Time Factors; Tritium; Urea | 1973 |
Amino acid metabolism of experimental granulation tissue in vitro.
Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cellulose; Chromatography, Ion Exchange; Collagen; Extracellular Space; Glutamates; Granuloma; Hydroxyproline; Lactates; Male; Monosaccharides; Ouabain; Potassium; Proline; Protein Biosynthesis; Rats; Sodium; Time Factors; Tritium; Urea | 1973 |
The collagen of chick embryonic notochord.
Topics: Amino Acids; Animals; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Culture Techniques; Hydroxyproline; Macromolecular Substances; Molecular Weight; Proline; Protein Denaturation; Tritium; Urea | 1973 |
Quantitative evaluation of nonspecific nitrogen sources for the growing chick.
Topics: Amino Acids, Essential; Animals; Arginine; Body Composition; Body Water; Body Weight; Chickens; Citrates; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Male; Nitrogen; Proline; Quaternary Ammonium Compounds; Urea; Valine | 1974 |
Chemical studies on amino acid acceptor ribonucleic acids. 8. Degradation of purified alanine Escherichia coli B transfer ribonucleic acid by pancreatic ribonuclease.
Topics: Alanine; Alkalies; Chromatography, Ion Exchange; Chromatography, Paper; Countercurrent Distribution; Electrophoresis; Escherichia coli; Esterases; Hydrogen-Ion Concentration; Micrococcal Nuclease; Micrococcus; Pancreas; Proline; Ribonucleases; RNA, Transfer; Spectrophotometry; Urea; Venoms | 1969 |
Arginine transport and metabolism in osmotically shocked and unshocked cells of Escherichia coli W.
Topics: Acetates; Arginine; Biological Transport; Canavanine; Carbon Isotopes; Carboxy-Lyases; Citrulline; Cold Temperature; Escherichia coli; Glutamates; Guanidines; Hydrochloric Acid; Leucine; Lysine; Ornithine; Osmolar Concentration; Proline; Tromethamine; Urea | 1969 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). II. Different patterns of amino acids and different levels of nitrogen supply.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Female; Glycine; Histidine; Humans; Injections, Intravenous; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Time Factors; Urea | 1970 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Effects on chick growth of adding various non-protein nitrogen sources or dried autoclaved poultry manure to diets containing crystalline essential amino acids.
Topics: Amino Acids; Animal Feed; Animals; Calcium; Chickens; Citrates; Diet; Feces; Glutamates; Lactates; Nitrogen; Proline; Quaternary Ammonium Compounds; Sucrose; Urea; Uric Acid | 1972 |
Membrane characteristics of human articular cartilage.
Topics: Adult; Cartilage, Articular; Cell Biology; Cell Membrane Permeability; Chlorides; Glucose; Humans; Iodine Isotopes; Mathematics; Proline; Proteins; Radioisotopes; Sodium; Sucrose; Sulfates; Tritium; Urea; Water | 1972 |
Influence of urea, biuret and starch on amino acid patterns in ruminal bacteria and blood plasma and on nitrogen balance of steers fed high fiber purified diets.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bacteria; Cattle; Cellulose; Culture Media; Depression, Chemical; Diet; Dietary Carbohydrates; Digestion; Feces; Glutamates; Hydrolysis; Indenes; Isoleucine; Ketones; Male; Metabolism; Nitrogen; Proline; Rumen; Starch; Stimulation, Chemical; Time Factors; Urea; Urease; Valine; Wood; Zea mays | 1971 |
Studies on protocollagen: identification of a precursor of proto alpha 1.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cyanogen Bromide; Hydroxylysine; Lathyrism; Mixed Function Oxygenases; Peptides; Proline; Protein Denaturation; Pyridines; Rats; Skin; Skull; Tritium; Urea | 1971 |
The characterization of hereditary abnormalities of keratin: Clouston's ectodermal dysplasia.
Topics: Ectodermal Dysplasia; Genes, Dominant; Hair; Humans; Keratosis; Nails, Malformed; Phenylalanine; Proline; Serine; Sulfur; Tyrosine; Urea; Water | 1971 |
Comparative physicochemical studies on vertebrate tropomyosins.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chickens; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Female; Gizzard, Avian; Hydrogen-Ion Concentration; Methods; Molecular Weight; Muscle Proteins; Muscles; Myocardium; Optical Rotatory Dispersion; Osmolar Concentration; Proline; Rabbits; Sheep; Species Specificity; Spectrophotometry; Ultracentrifugation; Ultraviolet Rays; Urea; Viscosity | 1969 |
Evidence from amino acid analysis for a relationship in the biosynthesis of gamma- and beta-caseins.
Topics: Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Computers; Electrophoresis, Disc; Glutamates; Hexoses; Histidine; Hydrogen-Ion Concentration; Lysine; Methods; Milk; Molecular Biology; Peptides; Phosphorus; Proline; Serine; Tryptophan; Urea | 1969 |
[On the influence of contraceptive pills on serum amino acids in comparison with results typical for sex, menstrual cycle and pregnancy].
Topics: Adult; Alanine; Amino Acids; Citric Acid Cycle; Contraceptives, Oral; Female; Glycine; Humans; Isoleucine; Leucine; Male; Menstruation; Methionine; Pregnancy; Proline; Sex Factors; Threonine; Tyrosine; Urea; Valine | 1969 |
Metabolism of bovine semen. XX. Role of ammonia in interactions between the citric acid and urea cycles.
Topics: Amino Acids; Ammonia; Animals; Arginase; Arginine; Carbamates; Carbon Dioxide; Carbon Isotopes; Cattle; Cell Fractionation; Citric Acid Cycle; Citrulline; Male; Ornithine; Ornithine Carbamoyltransferase; Oxygen Consumption; Phosphotransferases; Proline; Pyruvates; Rabbits; Semen; Spermatozoa; Urea; Valerates | 1969 |
The formation of collagen alpha chains in the absence of proline hydroxylation.
Topics: Age Factors; Animals; Buffers; Carbon Isotopes; Chick Embryo; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Electrophoresis, Disc; Foot; Lathyrism; Lysine; Methods; Methylcellulose; Nitriles; Penicillamine; Peptide Biosynthesis; Proline; Pyridines; Tibia; Tritium; Urea | 1970 |
Arginaseless Neurospora: genetics, physiology, and polyamine synthesis.
Topics: Amines; Arginase; Arginine; Butylamines; Crosses, Genetic; Culture Media; Genetic Complementation Test; Genetics, Microbial; Mutation; Neurospora; Ornithine; Ornithine Carbamoyltransferase; Proline; Protein Biosynthesis; Spermine; Transaminases; Urea | 1970 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). I. Individual non-essential amino acids.
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Creatinine; Female; Glutamates; Glycine; Histidine; Humans; Injections, Intravenous; Middle Aged; Nausea; Proline; Urea | 1970 |
The effect of neutral salts on gelatin and peptides containing L-proline.
Topics: Bromides; Calcium; Chlorides; Cyanides; Gelatin; Guanidines; Lithium; Optical Rotatory Dispersion; Peptides; Potassium; Potassium Chloride; Proline; Protein Denaturation; Salts; Sodium; Sodium Chloride; Urea; Viscosity | 1970 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
Cyanogen bromide fragments of human serum albumin.
Topics: Acetamides; Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cysteine; Electrophoresis; Formates; Guanidines; Humans; Hydrogen-Ion Concentration; Iodoacetates; Leucine; Methods; Naphthalenes; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Quaternary Ammonium Compounds; Serum Albumin; Sulfates; Sulfhydryl Reagents; Sulfonic Acids; Tetroses; Urea | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
Effect of pyruvate and other substrates on urea synthesis in rat liver slices.
Topics: Acetates; Alanine; Animals; Caprylates; Citrulline; Depression, Chemical; Electrophoresis; Fructose; Glucose; Lactates; Liver; Male; Ornithine; Paper; Proline; Pyruvates; Rats; Succinates; Urea | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
[Comparative study of the initial structure of muscle aldolase in normal and fasted rabbits].
Topics: Alanine; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Crystallization; Electrophoresis; Fasting; Fructose-Bisphosphate Aldolase; Muscles; Peptides; Proline; Rabbits; Sulfhydryl Compounds; Urea | 1968 |
Fractionation of histones from calf thymus and posterior silkglands by countercurrent distribution.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Bombyx; Cattle; Electrophoresis; Histones; Lysine; Methods; Phenylalanine; Proline; Thymus Gland; Trichloroacetic Acid; Urea | 1968 |
Chemical characterization of a non-covalently linked peptide from plakalbumin.
Topics: Alanine; Albumins; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Hydrazines; Methods; Ovalbumin; Peptides; Proline; Serine; Urea | 1969 |
Urea cycle in the silkworm, BOMBYX MORI.
Topics: Animals; Arginine; Autoradiography; Bombyx; Carbon Isotopes; Chromatography, Thin Layer; Citrulline; Deficiency Diseases; Diet; Glutamates; Ornithine; Proline; Urea | 1969 |
Comparison of the efficiency of proteins contained in lucerne hay and soya-bean meal for sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Fatty Acids; Female; Glycine max; Male; Nitrogen; Plant Proteins; Poaceae; Proline; Protein Biosynthesis; Rumen; Sheep; Urea; Valerates; Valine | 1969 |
A column chromatographic procedure for the fractionation of s-RNA.
Topics: Arginine; Chemistry Techniques, Analytical; Chromatography; Dextrans; Proline; RNA, Transfer; Saccharomyces; Tyrosine; Urea; Valine | 1965 |
On the conformation of caseins. Optical rotatory properties.
Topics: Caseins; Chemical Phenomena; Chemistry, Physical; Ethanol; Hydroxyproline; Proline; Solvents; Urea | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Distinct effects of glucagon and vasopressin on proline metabolism in isolated hepatocytes. The role of oxoglutarate dehydrogenase.
Topics: Amino Acids; Animals; Calcium; Glucagon; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Liver; Male; Proline; Rats; Rats, Inbred Strains; Urea; Vasopressins | 1984 |
Drug-protein conjugates--IV. The effect of acute renal failure on the disposition of [14C]captopril in the rat.
Topics: Acute Kidney Injury; Animals; Blood Proteins; Captopril; Carbon Radioisotopes; Creatinine; Kidney; Kinetics; Liver; Lung; Male; Proline; Protein Binding; Rats; Rats, Inbred Strains; Spleen; Tissue Distribution; Urea | 1983 |
On the possible significance of the transamidination reaction in evolution.
Topics: Amino Acids; Animals; Arginase; Biological Evolution; Bivalvia; Muscles; Oligochaeta; Ornithine-Oxo-Acid Transaminase; Phosphates; Proline; Species Specificity; Starfish; Transaminases; Urea; Urochordata | 1983 |
Restriction of C1 hemolytic function by human proline-rich salivary proteins.
Topics: Chromatography, Gel; Complement C1; Complement C1 Inactivator Proteins; Electrophoresis, Disc; Erythrocytes; Hemolysis; Humans; Peptides; Proline; Proline-Rich Protein Domains; Protein Denaturation; Salivary Proteins and Peptides; Urea | 1984 |
Mechanism for the unfolding and refolding of ribonuclease A. Kinetic studies utilizing spectroscopic methods.
Topics: Animals; Cattle; Endoribonucleases; In Vitro Techniques; Kinetics; Proline; Protein Conformation; Ribonuclease, Pancreatic; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Urea | 1983 |
Mechanism for the unfolding and refolding of ribonuclease A. Simulations using a simple model with no structural intermediates.
Topics: Kinetics; Models, Chemical; Proline; Protein Conformation; Ribonucleases; Stereoisomerism; Urea | 1983 |
Dynamism of rat liver ornithine metabolisms in relation to dietary high-protein stimulation of the urea cycle.
Topics: Animals; Arginine; Biological Transport, Active; Citrulline; Cytosol; Dietary Proteins; Liver; Mitochondria, Liver; Ornithine; Proline; Rats; Urea | 1982 |
Inhibition of urea-cycle activity by high concentrations of alanine.
Topics: Alanine; Ammonia; Animals; Argininosuccinate Synthase; Cytosol; In Vitro Techniques; Liver; Male; Proline; Rats; Urea | 1980 |
Separation and estimation of arginine-related metabolites in tissues.
Topics: Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Glutamates; Glutamine; Humans; Male; Ornithine; Polyamines; Proline; Rats; Urea | 1980 |
Metabolism of ornithine, alpha-ketoglutarate and arginine in isolated perfused rat liver.
Topics: Animals; Arginine; Glutamates; Ketoglutaric Acids; Liver; Male; Ornithine; Perfusion; Proline; Rats; Rats, Sprague-Dawley; Urea | 1995 |
A second nitrogen permease regulator in Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Base Sequence; DNA, Fungal; Fungal Proteins; Genes, Fungal; Genetic Complementation Test; Intracellular Signaling Peptides and Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Nitrogen; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Urea; Urease | 1995 |
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Creatinine; Diet; Food; Glutamic Acid; Glutamine; Male; Ornithine; Orotic Acid; Proline; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Urea | 1994 |
Folding mechanism of ribonuclease T1 in the absence of the disulfide bonds.
Topics: Circular Dichroism; Disulfides; In Vitro Techniques; Kinetics; Mutagenesis, Site-Directed; Proline; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Ribonuclease T1; Sodium Chloride; Structure-Activity Relationship; Urea | 1994 |
Conformational stability of alpha-lactalbumin missing a peptide bond between Asp66 and Pro67.
Topics: Amino Acid Sequence; Aspartic Acid; Circular Dichroism; Disulfides; Drug Stability; Ethanol; Formates; Guanidine; Guanidines; Lactalbumin; Proline; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics; Urea | 1994 |
Changes in serum amino acid concentrations during prolonged endurance running.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Osmolar Concentration; Physical Endurance; Proline; Running; Time Factors; Urea | 1993 |
The folding and stability of rhodanese are influenced by the replacement of glutamic acid 17 in the NH2-terminal helix by proline but not by glutamine.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Enzyme Stability; Escherichia coli; Glutamates; Glutamic Acid; Glutamine; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Proline; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Thiosulfate Sulfurtransferase; Urea | 1993 |
Improvement of culture conditions for L-proline production by a recombinant strain of Serratia marcescens.
Topics: Ammonia; Culture Media; DNA, Recombinant; Hydrogen-Ion Concentration; Magnesium Sulfate; Phosphates; Plasmids; Potassium Compounds; Proline; Serratia marcescens; Spectrophotometry, Ultraviolet; Stereoisomerism; Sucrose; Urea | 1993 |
The refolding of cis- and trans-peptidylprolyl isomers of barstar.
Topics: Bacterial Proteins; Base Sequence; Circular Dichroism; Cysteine; Disulfides; Isomerism; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Ribonucleases; Thermodynamics; Urea | 1993 |
Reciprocal effects of proline and glutamine on glycogenesis from glucose and ureagenesis in isolated, perfused rat livers.
Topics: Animals; Carbamyl Phosphate; Glucose; Glutamine; Glycogen; Liver; Proline; Rats; Urea | 1993 |
Equilibrium dissociation and unfolding of nucleoside diphosphate kinase from Dictyostelium discoideum. Role of proline 100 in the stability of the hexameric enzyme.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Circular Dichroism; Dictyostelium; Enzyme Stability; Glycine; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Oligodeoxyribonucleotides; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Urea | 1993 |
Effects of betaines and urine on the antibacterial activity of aminoglycosides.
Topics: Acetylcarnitine; Anti-Bacterial Agents; Betaine; Culture Media; Drug Interactions; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Glucose Solution, Hypertonic; Humans; Hypertonic Solutions; Microbial Sensitivity Tests; Osmolar Concentration; Polymers; Proline; Sodium Chloride; Urea | 1993 |
Destabilizing effect of proline substitutions in two helical regions of T4 lysozyme: leucine 66 to proline and leucine 91 to proline.
Topics: Circular Dichroism; Crystallography, X-Ray; Enzyme Stability; Hot Temperature; Leucine; Muramidase; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Spectrophotometry, Ultraviolet; Urea | 1996 |
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning | 1997 |
Pro108 is important for folding and stabilization of adrenal ferredoxin, but does not influence the functional properties of the protein.
Topics: Adrenal Glands; Adrenodoxin; Animals; Cattle; Circular Dichroism; Electron Spin Resonance Spectroscopy; Escherichia coli; Gene Expression; Kinetics; Models, Molecular; Oxidation-Reduction; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Spectrophotometry; Temperature; Urea | 1997 |
Multiple unfolded states of UDP-galactose 4-epimerase from yeast Kluyveromyces fragilis. Involvement of proline cis-trans isomerization in reactivation.
Topics: Anilino Naphthalenesulfonates; Chromatography, Gel; Dimerization; Enzyme Activation; Fluorescent Dyes; Hydrogen-Ion Concentration; Isomerism; Kinetics; Kluyveromyces; NAD; Peptidylprolyl Isomerase; Proline; Protein Binding; Protein Denaturation; Protein Folding; Scattering, Radiation; Spectrometry, Fluorescence; Temperature; UDPglucose 4-Epimerase; Urea | 1997 |
Comparative study of enzymes related to proline metabolism in tepary bean (Phaseolus acutifolius) and common bean (Phaseolus vulgaris) under drought and irrigated conditions, and various urea concentrations.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Electrophoresis; Fabaceae; Glutamate Dehydrogenase; Isoenzymes; Molecular Weight; Oxidoreductases Acting on CH-NH Group Donors; Plant Proteins; Plants, Medicinal; Proline; Proline Oxidase; Spectrophotometry; Urea; Water | 1998 |
Stability and folding of the tumour suppressor protein p16.
Topics: Circular Dichroism; Cyclin-Dependent Kinase Inhibitor p16; Drug Stability; Escherichia coli; Humans; In Vitro Techniques; Kinetics; Models, Molecular; Mutation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Thermodynamics; Urea | 1999 |
The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate.
Topics: Apoproteins; Azurin; Circular Dichroism; Dose-Response Relationship, Drug; Isomerism; Kinetics; Models, Chemical; Models, Molecular; Paracoccus denitrificans; Proline; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Thermodynamics; Urea | 1999 |
Arginine catabolism in the cyanobacterium Synechocystis sp. Strain PCC 6803 involves the urea cycle and arginase pathway.
Topics: Arginase; Arginine; Carbon Radioisotopes; Cyanobacteria; Ornithine; Proline; Urea | 2000 |
Fast folding of Escherichia coli cyclophilin A: a hypothesis of a unique hydrophobic core with a phenylalanine cluster.
Topics: Amino Acid Sequence; Catalysis; Circular Dichroism; Conserved Sequence; Dose-Response Relationship, Drug; Escherichia coli; Isomerism; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Peptidylprolyl Isomerase; Phenylalanine; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Renaturation; Sequence Alignment; Thermodynamics; Urea | 2000 |
Splanchnic and leg exchange of amino acids and ammonia in acute liver failure.
Topics: Adult; Alanine; Amino Acids; Ammonia; Blood Urea Nitrogen; Citrulline; Female; Femoral Artery; Femoral Vein; Fibrosis; Glutamine; Humans; Leg; Liver Failure, Acute; Male; Middle Aged; Predictive Value of Tests; Proline; Splanchnic Circulation; Urea | 2000 |
Fluorescence energy transfer indicates similar transient and equilibrium intermediates in staphylococcal nuclease folding.
Topics: Amino Acid Substitution; Anilino Naphthalenesulfonates; Anions; Circular Dichroism; Cysteine; Energy Transfer; Fluorescence; Guanidine; Hydrogen-Ion Concentration; Kinetics; Micrococcal Nuclease; Models, Molecular; Pliability; Proline; Protein Binding; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Secondary; Thermodynamics; Titrimetry; Tryptophan; Urea | 2000 |
Sequence conservation provides the best prediction of the role of proline residues in p13suc1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Cycle Proteins; Conserved Sequence; Dimerization; Fungal Proteins; Models, Molecular; Molecular Sequence Data; Multigene Family; Mutation; Proline; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Alignment; Structure-Activity Relationship; Thermodynamics; Urea | 2000 |
Multiple roles of prolyl residues in structure and folding.
Topics: Circular Dichroism; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; Mutation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Receptors, Retinoic Acid; Temperature; Thermodynamics; Urea | 2000 |
Initial denaturing conditions influence the slow folding phase of acylphosphatase associated with proline isomerization.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Circular Dichroism; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Glycine; Humans; Isomerism; Kinetics; Models, Chemical; Muscles; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trifluoroethanol; Urea | 2000 |
Modular motif, structural folds and affinity profiles of the PEVK segment of human fetal skeletal muscle titin.
Topics: Actins; Amino Acid Motifs; Amino Acid Sequence; Blotting, Western; Calcium; Calmodulin; Carrier Proteins; Cell Adhesion; Circular Dichroism; Cloning, Molecular; Connectin; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Hot Temperature; Humans; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Peptides; Proline; Protein Binding; Protein Conformation; Protein Folding; Protein Kinases; RNA-Binding Proteins; S100 Proteins; Sequence Homology, Amino Acid; Surface Plasmon Resonance; Temperature; Time Factors; Urea | 2001 |
A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding.
Topics: Anilino Naphthalenesulfonates; Azurin; Circular Dichroism; Cyclophilin A; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Proline; Protein Folding; Protein Structure, Secondary; Sodium; Stereoisomerism; Time Factors; Ultracentrifugation; Urea | 2001 |
Chemical chaperones regulate molecular chaperones in vitro and in cells under combined salt and heat stresses.
Topics: Adaptation, Biological; Bacterial Proteins; Betaine; Chaperonin 60; Escherichia coli; Escherichia coli Proteins; Glycerol; Heat-Shock Proteins; Hot Temperature; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Malate Dehydrogenase; Molecular Chaperones; Osmotic Pressure; Proline; Protein Denaturation; Protein Folding; Salts; Trehalose; Urea; Viscosity | 2001 |
Compensatory changes in enzymes of arginine metabolism during renal hypertrophy in mice.
Topics: Amidinotransferases; Animals; Arginine; Hypertrophy; Kidney; Kidney Glomerulus; Male; Mice; Models, Biological; Nephrectomy; Organ Size; Ornithine-Oxo-Acid Transaminase; Proline; Protein Denaturation; Time Factors; Urea | 2001 |
Comparison of the folding processes of T. thermophilus and E. coli ribonucleases H.
Topics: Circular Dichroism; Escherichia coli; Fluorescence; Hydrogen; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Renaturation; Ribonuclease H; Thermodynamics; Thermus thermophilus; Urea | 2002 |
Parallel channels and rate-limiting steps in complex protein folding reactions: prolyl isomerization and the alpha subunit of Trp synthase, a TIM barrel protein.
Topics: Bacterial Proteins; Circular Dichroism; Cyclophilins; Isomerism; Models, Molecular; Mutation; Proline; Protein Folding; Protein Structure, Tertiary; Thermodynamics; Tryptophan Synthase; Urea | 2002 |
Folding and assembly of lambda Cro repressor dimers are kinetically limited by proline isomerization.
Topics: Bacteriophage lambda; Carrier Proteins; Catalysis; Circular Dichroism; Dimerization; DNA-Binding Proteins; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Hydrogen-Ion Concentration; Kinetics; Peptidylprolyl Isomerase; Proline; Protein Denaturation; Protein Folding; Protein Processing, Post-Translational; Repressor Proteins; Tryptophan; Urea; Viral Proteins; Viral Regulatory and Accessory Proteins | 2002 |
The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1.
Topics: Glutathione Transferase; Glycine; Humans; Isoenzymes; Kinetics; Mutation; Proline; Protein Denaturation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Urea | 2003 |
Malleable conformation of the elastic PEVK segment of titin: non-co-operative interconversion of polyproline II helix, beta-turn and unordered structures.
Topics: Amino Acid Motifs; Amino Acid Sequence; Circular Dichroism; Connectin; Elasticity; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Muscle Proteins; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Peptides; Proline; Protein Conformation; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Salts; Stereoisomerism; Trifluoroethanol; Urea; Valine | 2003 |
Proline replacements and the simplification of the complex, parallel channel folding mechanism for the alpha subunit of Trp synthase, a TIM barrel protein.
Topics: Circular Dichroism; Cyclophilins; DNA Mutational Analysis; Escherichia coli; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Proline; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Thermodynamics; Time Factors; Tryptophan Synthase; Ultraviolet Rays; Urea | 2003 |
CENTRIFUGAL PAPER CHROMATOGRAPHY AND SOME OF ITS APPLICATIONS.
Topics: Anthelmintics; Chromatography; Chromatography, Paper; Fumarates; Histidine; Leucine; Malates; Maleates; Organophosphate Poisoning; Phosphorus; Poisons; Proline; Research; Tetracycline; Triamcinolone; Urea | 1964 |
ARGININE AS A PRECURSOR OF PYRIMIDINES IN STRAIN L-929 FIBROBLASTS INFECTED WITH PLEUROPNEUMONIA-LIKE ORGANISMS.
Topics: Arginase; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Connective Tissue; Fibroblasts; Glutamine; Ligases; Metabolism; Mycoplasma; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Phosphates; Phosphotransferases; Proline; Proteins; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Uracil; Urea; Ureohydrolases | 1964 |
RECENT DEVELOPMENTS IN THE UNDERSTANDING OF AMINO-ACID AND PROTEIN METABOLISM BY SCHISTOSOMA MANSONI IN VITRO.
Topics: Alanine; Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Hemoglobins; Histidine; In Vitro Techniques; Ornithine; Peptides; Proline; Proteins; Radiometry; Research; Schistosoma; Schistosoma mansoni; Tryptophan; Urea | 1965 |
Thermodynamic effects of replacements of Pro residues in helix interiors of maltose-binding protein.
Topics: Amino Acid Substitution; Binding Sites; Calorimetry; Carrier Proteins; Genotype; Hydrogen-Ion Concentration; Maltose-Binding Proteins; Mutation; Proline; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature; Thermodynamics; Urea | 2003 |
Kinetics of asparaginase II fermentation in Saccharomyces cerevisiae ure2dal80 mutant: effect of nitrogen nutrition and pH.
Topics: Asparaginase; Biotechnology; Fermentation; Hydrogen-Ion Concentration; Kinetics; Mutation; Nitrogen; Proline; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Time Factors; Urea | 2004 |
Replacement of proline with valine does not remove an apparent proline isomerization-dependent folding event in CRABP I.
Topics: Amino Acid Substitution; Animals; Circular Dichroism; Isomerism; Kinetics; Ligands; Mice; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Receptors, Retinoic Acid; Tretinoin; Urea; Valine | 2004 |
Folding and domain-domain interactions of the chaperone PapD measured by 19F NMR.
Topics: Circular Dichroism; Escherichia coli Proteins; Fluorine; Kinetics; Models, Molecular; Molecular Chaperones; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; p-Fluorophenylalanine; Peptide Fragments; Periplasmic Proteins; Phenylalanine; Proline; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Stereoisomerism; Urea | 2004 |
Arginine synthesis does not occur during first-pass hepatic metabolism in the neonatal piglet.
Topics: Amino Acids; Ammonia; Animal Feed; Animals; Animals, Newborn; Arginine; Blood Urea Nitrogen; Deuterium; Enteral Nutrition; Liver; Male; Ornithine; Proline; Random Allocation; Swine; Urea | 2005 |
Experimental characterization of the folding kinetics of the notch ankyrin domain.
Topics: Animals; Ankyrin Repeat; Drosophila; Drosophila Proteins; Isomerism; Kinetics; Membrane Proteins; Models, Chemical; Models, Molecular; Proline; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Receptors, Notch; Thermodynamics; Urea | 2005 |
P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate.
Topics: Alanine; Amino Acid Substitution; Cross-Linking Reagents; Dimerization; Factor For Inversion Stimulation Protein; Glutaral; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Proline; Protein Denaturation; Temperature; Urea | 2005 |
Factor XIIIa mediated attachment of S. aureus fibronectin-binding protein A (FnbA) to fibrin: identification of Gln103 as a major cross-linking site.
Topics: Adhesins, Bacterial; Base Sequence; Binding Sites; Catalysis; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrin; Glutamine; Leucine; Lysine; Proline; Staphylococcus aureus; Time Factors; Urea | 2006 |
Biophysical characterisation of the small ankyrin repeat protein myotrophin.
Topics: Animals; Ankyrin Repeat; Biophysics; Intercellular Signaling Peptides and Proteins; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Statistical; Mutation; Proline; Protein Conformation; Protein Folding; Rats; Thermodynamics; Urea | 2007 |
Comparison of C40/82A and P27A C40/82A barstar mutants using 19F NMR.
Topics: Bacterial Proteins; Dose-Response Relationship, Drug; Fluorine; Hydrophobic and Hydrophilic Interactions; Motion; Mutation; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Temperature; Tryptophan; Ultracentrifugation; Urea | 2007 |
Effects of osmolytes on RNA secondary and tertiary structure stabilities and RNA-Mg2+ interactions.
Topics: Base Sequence; Betaine; Cations, Divalent; Ethylene Glycol; Magnesium; Methanol; Methylamines; Molecular Sequence Data; Nucleic Acid Conformation; Osmotic Pressure; Proline; RNA; RNA Stability; Sucrose; Sugar Alcohols; Thermodynamics; Urea | 2007 |
Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue.
Topics: Animals; Biological Availability; Haplorhini; Hepacivirus; Proline; Rats; Serine Proteinase Inhibitors; Structure-Activity Relationship; Urea; Viral Nonstructural Proteins | 2008 |
Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis.
Topics: Arabidopsis; Arginine; Genetic Complementation Test; Green Fluorescent Proteins; Mitochondria; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Phenotype; Proline; Protein Transport; Recombinant Fusion Proteins; Sodium Chloride; Urea | 2008 |
Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes.
Topics: Apoptosis; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Genome, Human; Genomics; Humans; Models, Biological; Ornithine-Oxo-Acid Transaminase; Polymorphism, Single Nucleotide; Proline; Proline Oxidase; Response Elements; Time Factors; Tissue Distribution; Urea | 2008 |
Diversity-oriented synthesis of a drug-like system displaying the distinctive N-->C=O interaction.
Topics: Aldehydes; Combinatorial Chemistry Techniques; Cyclization; HIV Protease; HIV-1; Hydrazines; Magnetic Resonance Spectroscopy; Molecular Conformation; Piperidines; Proline; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Urea | 2008 |
Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.
Topics: Administration, Oral; Animals; Antiviral Agents; Carbamates; Combinatorial Chemistry Techniques; Drug Design; Hepacivirus; Male; Models, Molecular; Molecular Structure; Proline; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Structure-Activity Relationship; Urea; Viral Nonstructural Proteins | 2008 |
Use of bifunctional ureas to increase the rate of proline-catalyzed alpha-aminoxylations.
Topics: Amines; Catalysis; Cross-Linking Reagents; Kinetics; Proline; Solubility; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Urea | 2009 |
Preclinical characterization of the antiviral activity of SCH 900518 (narlaprevir), a novel mechanism-based inhibitor of hepatitis C virus NS3 protease.
Topics: Antiviral Agents; Cyclopropanes; Dipeptides; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Viral; Genotype; Hepacivirus; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Kinetics; Leucine; Mutation; Proline; Protease Inhibitors; Recombinant Proteins; Replicon; Sulfones; Urea; Viral Nonstructural Proteins | 2010 |
Solid-state dynamic nuclear polarization at 263 GHz: spectrometer design and experimental results.
Topics: Cyclic N-Oxides; Magnetic Resonance Spectroscopy; Microwaves; Proline; Propanols; Temperature; Urea | 2010 |
Compatible solutes: Thermodynamic properties and biological impact of ectoines and prolines.
Topics: Amino Acids, Diamino; Osmotic Pressure; Proline; Salts; Solubility; Solutions; Temperature; Thermodynamics; Urea; Water | 2010 |
Acetoacetanilides as masked isocyanates: facile and efficient synthesis of unsymmetrically substituted ureas.
Topics: Acetanilides; Isocyanates; Models, Molecular; Molecular Structure; Proline; Stereoisomerism; Urea | 2010 |
Using temperature to optimize resolution and reduce analysis times for bioanalytical diastereomer LC-MS/MS separations.
Topics: Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclopropanes; Dipeptides; Humans; Leucine; Proline; Reproducibility of Results; Stereoisomerism; Sulfones; Tandem Mass Spectrometry; Temperature; Time Factors; Urea | 2011 |
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drugs, Investigational; Enzyme Inhibitors; Hepacivirus; Humans; Hydroxyprostaglandin Dehydrogenases; Hydroxysteroid Dehydrogenases; Kinetics; Liver; Molecular Structure; Oligopeptides; Oxidation-Reduction; Proline; Recombinant Proteins; Serine Proteinase Inhibitors; Stereoisomerism; Subcellular Fractions; Urea; Viral Nonstructural Proteins | 2011 |
Implementation of high-temperature superficially porous technologies for rapid LC-MS/MS diastereomer bioanalysis.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclopropanes; Dipeptides; Humans; Leucine; Lysophosphatidylcholines; Phosphatidylcholines; Proline; Stereoisomerism; Sulfones; Tandem Mass Spectrometry; Technology, Pharmaceutical; Temperature; Urea | 2011 |
Precision and accuracy in the quantitative analysis of biological samples by accelerator mass spectrometry: application in microdose absolute bioavailability studies.
Topics: Administration, Oral; Adult; Antiviral Agents; Calibration; Chromatography, Liquid; Cyclopropanes; Dipeptides; Humans; Injections, Intravenous; Leucine; Male; Middle Aged; Proline; Reproducibility of Results; Sensitivity and Specificity; Sulfones; Tandem Mass Spectrometry; Urea; Young Adult | 2011 |
A nonpeptidic reverse-turn scaffold stabilized by urea-based dual intramolecular hydrogen bonding.
Topics: Cyclohexylamines; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Peptides; Proline; Urea | 2011 |
Backbone cyclic peptide inhibitors of protein kinase B (PKB/Akt).
Topics: Amides; Arginine; Catalytic Domain; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Peptide Library; Peptides, Cyclic; Peptidomimetics; Proline; Proto-Oncogene Proteins c-akt; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Thermodynamics; Urea | 2011 |
Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains.
Topics: Betaine; Glycerol; Models, Biological; Osmolar Concentration; Proline; Protein Stability; Proteins; Solubility; Urea | 2011 |
Insight into the structural requirements of narlaprevir-type inhibitors of NS3/NS4A protease based on HQSAR and molecular field analyses.
Topics: Antiviral Agents; Carrier Proteins; Cyclopropanes; Dipeptides; Drug Design; Hepacivirus; Hepatitis C; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Models, Molecular; Proline; Quantitative Structure-Activity Relationship; Sulfones; Urea; Viral Nonstructural Proteins | 2012 |
Discovery and structure-activity relationships of urea derivatives as potent and novel CCR3 antagonists.
Topics: Drug Evaluation, Preclinical; Humans; Naphthalenes; Proline; Protein Binding; Pyrrolidines; Receptors, CCR3; Structure-Activity Relationship; Urea | 2012 |
Synthesis of deoxynucleoside triphosphates that include proline, urea, or sulfonamide groups and their polymerase incorporation into DNA.
Topics: DNA; DNA Polymerase I; DNA-Directed DNA Polymerase; Hydrogen Bonding; Polymerase Chain Reaction; Proline; Sulfonamides; Urea; Uridine Triphosphate | 2012 |
Study of the fragmentation of arginine isobutyl ester applied to arginine quantification in Aedes aegypti mosquito excreta.
Topics: Aedes; Animals; Arginine; Esters; Feces; Female; Humans; Proline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Urea | 2012 |
Inhibition of protein glycation by urea and thiourea derivatives of glycine/proline conjugated benzisoxazole analogue - synthesis and structure-activity studies.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Glycine; Isoxazoles; Molecular Structure; Proline; Serum Albumin, Bovine; Structure-Activity Relationship; Urea | 2013 |
Quantifying additive interactions of the osmolyte proline with individual functional groups of proteins: comparisons with urea and glycine betaine, interpretation of m-values.
Topics: Betaine; Models, Chemical; Osmolar Concentration; Proline; Serum Albumin, Bovine; Solubility; Urea | 2013 |
Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
Topics: Betaine; Circular Dichroism; Concanavalin A; Dimerization; Hydrogen-Ion Concentration; Indicators and Reagents; Methylamines; Models, Molecular; Osmolar Concentration; Proline; Protein Interaction Domains and Motifs; Protein Stability; Sarcosine; Secondary Metabolism; Sorbitol; Sucrose; Thermodynamics; Titrimetry; Trehalose; Urea | 2013 |
Synthesis and folding propensity of aliphatic oligoureas containing repeats of proline-type units.
Topics: Circular Dichroism; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Proline; Pyrrolidines; Urea | 2014 |
New ureas containing glycosyl and diphenylphosphinyl scaffolds: synthesis and the first attempts to use them in asymmetric synthesis.
Topics: Catalysis; Chemistry Techniques, Synthetic; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Polysaccharides; Proline; Stereoisomerism; Urea | 2014 |
Study of the effects of proline, phenylalanine, and urea foliar application to Tempranillo vineyards on grape amino acid content. Comparison with commercial nitrogen fertilisers.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fertilizers; Nitrogen; Phenylalanine; Proline; Urea; Vitis; Wine | 2014 |
Analysis of strains lacking known osmolyte accumulation mechanisms reveals contributions of osmolytes and transporters to protection against abiotic stress.
Topics: Betaine; Culture Media; Escherichia coli; Methylamines; Osmotic Pressure; Proline; Sodium Chloride; Stress, Physiological; Sulfonium Compounds; Temperature; Urea | 2014 |
Computational study on the molecular mechanisms of drug resistance of Narlaprevir due to V36M, R155K, V36M+R155K, T54A, and A156T mutations of HCV NS3/4A protease.
Topics: Antiviral Agents; Cyclopropanes; Dipeptides; Drug Resistance, Viral; Genes, Viral; Hepacivirus; Leucine; Molecular Dynamics Simulation; Mutation; Proline; Sulfones; Urea; Viral Nonstructural Proteins | 2014 |
Impact of fetal chromosomal disorders on maternal blood metabolome: toward new biomarkers?
Topics: Acetates; Adult; Biomarkers; Blood Glucose; Case-Control Studies; Chromosome Disorders; Citric Acid; Creatinine; Down Syndrome; Fatty Acids; Female; Humans; Ketone Bodies; Lipid Metabolism; Lipoproteins, HDL; Lipoproteins, VLDL; Magnetic Resonance Spectroscopy; Metabolome; Methanol; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Proline; Pyruvic Acid; Serum Albumin; Urea; Young Adult | 2015 |
α-Quaternary Proline Derivatives by Intramolecular Diastereoselective Arylation of N-Carboxamido Proline Ester Enolates.
Topics: Bridged Bicyclo Compounds; Carboxylic Acids; Cyclization; Esters; Molecular Structure; Proline; Stereoisomerism; Urea | 2015 |
The modification of Gat1p in nitrogen catabolite repression to enhance non-preferred nitrogen utilization in Saccharomyces cerevisiae.
Topics: Catabolite Repression; GATA Transcription Factors; Gene Expression Regulation, Fungal; Mutation; Nitrogen; Nuclear Localization Signals; Proline; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Urea | 2016 |
Reorientation Motion and Preferential Interactions of a Peptide in Denaturants and Osmolyte.
Topics: Fluorescence Polarization; Guanidine; Molecular Dynamics Simulation; Motion; Osmolar Concentration; Peptides; Proline; Protein Denaturation; Urea; Water | 2016 |
Self-assembled vesicles of urea-tethered foldamers as hydrophobic drug carriers.
Topics: Antineoplastic Agents; Curcumin; Drug Carriers; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; ortho-Aminobenzoates; Proline; Urea | 2016 |
Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS.
Topics: Amino Acids, Branched-Chain; Asian People; Blood Glucose; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Furans; Gas Chromatography-Mass Spectrometry; Glycated Hemoglobin; Glycerol; Humans; Linoleic Acid; Lysophospholipids; Metabolomics; Oleic Acid; Proline; Propionates; Urea | 2016 |
Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors.
Topics: Amides; Animals; Biological Availability; Class I Phosphatidylinositol 3-Kinases; Deuterium; Enzyme Inhibitors; Kinetics; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Rats; Thiazoles; Urea | 2016 |
Influence of partial or total replacement of glycerol by alternative cryoprotectants in Ghent freezing extender on post-thaw sperm quality in stallions.
Topics: Animals; Betaine; Chromatin; Cryopreservation; Cryoprotective Agents; Freezing; Glucose; Glycerol; Horses; Male; Membrane Potential, Mitochondrial; Proline; Semen Analysis; Semen Preservation; Sperm Motility; Trehalose; Urea | 2017 |
G-quadruplex binding ability of TLS/FUS depends on the β-spiral structure of the RGG domain.
Topics: Arginine; G-Quadruplexes; Potassium Chloride; Proline; Protein Binding; Protein Domains; Repetitive Sequences, Amino Acid; RNA-Binding Protein FUS; Urea | 2018 |
Alanine, proline and urea are major organic osmolytes in the snail
Topics: Alanine; Animals; Fresh Water; Germany; Osmotic Pressure; Proline; Saline Waters; Salt Stress; Snails; Urea | 2019 |
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea | 2019 |
Steady-State and Pulse-Chase Analyses of Fibrillar Collagen.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Fibrillar Collagens; Fibroblasts; Humans; Proline; Protein Processing, Post-Translational; Tritium; Urea | 2019 |
Intrinsically disordered proteins access a range of hysteretic phase separation behaviors.
Topics: Amino Acids; Antifreeze Proteins; Circular Dichroism; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Nanoparticles; Phase Transition; Proline; Temperature; Urea | 2019 |
Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir.
Topics: Coronavirus 3C Proteases; COVID-19; COVID-19 Drug Treatment; Cyclopropanes; Cysteine Proteinase Inhibitors; Hepacivirus; Humans; Leucine; Proline; SARS-CoV-2; Sulfones; Urea | 2021 |
Probing the Internal Dynamics and Shape of Simple Peptides in Urea, Guanidinium Hydrochloride, and Proline Solutions with Time-Resolved Fluorescence Anisotropy and Atomistic Cosolvent Simulations.
Topics: Fluorescence Polarization; Guanidine; Peptides; Proline; Urea | 2021 |
Solvation stabilizes intercarbonyl n→π* interactions and polyproline II helix.
Topics: Formaldehyde; Peptides; Proline; Proteins; Solvents; Urea | 2022 |
Stability of the Aβ42 Peptide in Mixed Solutions of Denaturants and Proline.
Topics: Amyloid beta-Peptides; Humans; Molecular Dynamics Simulation; Peptide Fragments; Proline; Urea | 2023 |
Transcriptome Analysis of Redox Systems and Polyamine Metabolic Pathway in Hepatoma and Non-Tumor Hepatocyte-like Cells.
Topics: Carcinoma, Hepatocellular; Gene Expression Profiling; Hepatocytes; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Oxidation-Reduction; Polyamines; Proline; Reactive Oxygen Species; Urea | 2023 |
Effective Reduction of Tau Amyloid Aggregates in the Presence of Cyclophilin from
Topics: Allergens; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Cyclophilins; Pollen; Proline; tau Proteins; Urea | 2023 |