proline has been researched along with transforming growth factor beta in 74 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 31 (41.89) | 18.2507 |
2000's | 34 (45.95) | 29.6817 |
2010's | 8 (10.81) | 24.3611 |
2020's | 1 (1.35) | 2.80 |
Authors | Studies |
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Armendariz-Borunda, J; Katayama, K; Seyer, JM | 1 |
Genge, BR; Ishikawa, Y; Wu, LN; Wuthier, RE | 1 |
Carette, MJ; Ferguson, MW; Foreman, DM; Schor, SL; Sharpe, PM | 1 |
Charette, MF; Rutherford, RB; Ryan, ME; TrailSmith, MD | 1 |
Creely, JJ; DiMari, SJ; Haralson, MA; Howe, AM | 1 |
Cunliffe, WJ; Hey, KB; Jutley, JK; Wood, EJ | 1 |
Ericksen, M; Sharma, K; Wolf, G; Ziyadeh, FN | 1 |
Fitzgerald, MX; MacFarlane, DJ; O'Connor, CM | 1 |
Ballermann, BJ; Choi, ME; Huang, Q; Kim, EG | 1 |
Abiko, Y; Moriya, Y; Shibata, Y; Takiguchi, H; Yoshida, W | 1 |
Grütter, MG; Schlunegger, MP | 1 |
Kostenuik, PJ; Orr, FW; Sanchez-Sweatman, O; Singh, G | 1 |
Alevizopoulos, A; Dusserre, Y; Mermod, N; Tsai-Pflugfelder, M; von der Weid, T; Wahli, W | 1 |
Irwin, CR; James, JA; Linden, GJ | 1 |
Altieri, P; Caridi, G; Degl'Innocenti, ML; Ghiggeri, GM; Gusmano, R; Perfumo, F; Trivelli, A | 1 |
Alevizopoulos, A; Mermod, N | 1 |
Cao, M; Georgescu, HI; Kavalkovich, KW; Levine, RE; Marui, T; Niyibizi, C; Woo, SL | 1 |
Craven, PA; DeRubertis, FR; Felder, J; Phillips, S; Studer, RK | 1 |
Rosenthal, AK; Ryan, LM | 1 |
Boers, W; Brand, HS; Chamuleau, RA; Linthorst, C; Tiggelman, AM | 1 |
Kim, HD; Valentini, RF | 1 |
Hori, M; Horio, M; Imai, E; Kitamura, H; Matusoka, Y; Sugiura, T; Yamauchi, A | 1 |
Goto, J; Harada, A; Hase, M; Ikeda, K; Kanematsu, M; Miyauchi, A; Okuizumi, H; Takagi, Y; Takai, H; Yamada, Y | 1 |
Campbell, ID; Downing, K; Handford, PA; Knott, V; Werner, JM; Yuan, X | 1 |
Evans, S; Krob, SL; Lin, JJ; Lin, JL; Reiter, RS; Schultheiss, TM; Wang, DZ; Wang, Q; Williams, HS | 1 |
Auster, A; Covarrubias-Pinedo, A; Domínguez-Rosales, JA; Fontana, L; García-Trevijano, ER; Iraburu, MJ; Rojkind, M | 1 |
Chu, AJ; Prasad, JK | 1 |
Bennett, K; Dota, A; Kawasaki, S; Kinoshita, S; Nishida, K; Quantock, AJ | 1 |
Bertschin, S; Eickelberg, O; Erne, P; Köhler, E; Perruchoud, AP; Reichenberger, F; Roth, M; Woodtli, T | 1 |
Endo, S; Fujiki, K; Hotta, Y; Ishida, N; Kanai, A; Nakayasu, K; Nguyen, TH; Yamaguchi, T | 1 |
Canady, JW; Chun, ML; Coberly, DM; Pang, JC; Sandra, A; Thompson, SA | 1 |
Hiraga, S; Iwata, K; Kaji, T; Katsuda, S; Koizumi, F; Nakanishi, I; Okada, Y; Ueda, Y; Zisaki, F | 1 |
Han, DC; Hoffman, BB; Isono, M; Mogyorósi, A; Ziyadeh, FN | 1 |
Yamada, Y | 1 |
Baan, CC; Balk, AH; Holweg, CT; Maat, LP; Niesters, HG; van Riemsdijk, IC; Vantrimpont, PJ; Weimar, W | 1 |
Durante, W; Liao, L; Peyton, KJ; Reyna, SV; Schafer, AI | 1 |
Bamba, T; Fujiyama, Y; Nakamura, F; Saotome, T; Shintani, Y | 1 |
Balducci, C; Baroni, T; Becchetti, E; Belcastro, S; Lilli, C; Locci, P; Marinucci, L | 1 |
Dyer, PA; Haworth, SE; Hull, PS; Irwin, CR; James, JA; Linden, GJ; Marley, JJ; Maxwell, AP; McNamee, P; Middleton, D; Poulton, KV; Short, CD | 1 |
Chiu, C; Maddock, DA; Souza, KP; Townsend, AR; Wan, Y; Zhang, Q | 1 |
Durante, W; Ensenat, D; Hassan, S; Reyna, SV; Schafer, AI | 1 |
Chang, NS | 1 |
Chen, S; Han, DC; Iglesias-de la Cruz, MC; Isono, M; Kalluri, R; Kouahou, M; Mundel, P; Ziyadeh, FN | 1 |
Gore-Hyer, E; Greene, EL; Grotendorst, G; Hazen-Martin, D; Lo, S; Markiewicz, M; Shegogue, D; Trojanowska, M | 1 |
Kent, KC; Kubota, K; Liu, B; Louie, O; Okazaki, J | 1 |
Browner, W; Cauley, J; Kahn, A; Morin, P; Saiz, R; Ziv, E | 1 |
Ancochea, J; Campistol, JM; Inigo, P; Lario, S; Marin-Arguedas, A; Morell, F; Mullol, J; Picado, C; Rodriguez-Arias, JM; Rodriguez-Becerra, E; Ruiz-Manzano, J; Sanz, S; Xaubet, A | 1 |
Chang-Claude, J; Dunning, AM; Easton, DF; Ellis, PD; Healey, CS; Kataja, V; Kemp, PR; Kirschenlohr, HL; Luben, RN; Mannermaa, A; McBride, S; Metcalfe, JC; Pharoah, PD; Ponder, BA | 1 |
Whyte, MK | 1 |
Gilbert, RE; Kelly, DJ; Mifsud, S; Pollock, CA; Qi, W; Wilkinson-Berka, JL; Zhang, Y | 1 |
Fulcher, GR; Polhill, TS; Pollock, CA; Poronnik, P; Saad, S | 1 |
Chonan, S; Gao, N; Murakami, S; Saito, S; Saitoh, M; Sato-Watanabe, M; Sugawara, K; Takashima, H; Yamamoto, K; Yang, J; Yoshimura, H; Zhang, X | 1 |
Durante, W; Ensenat, D; Johnson, FK; Reyna, SV; Schafer, AI; Wang, H | 1 |
Nishanian, TG; Waldman, T | 1 |
Affeldt, JA; Aldave, AJ; Gutmark, JG; Klintworth, GK; Meallet, MA; Rao, NA; Small, KW; Udar, N; Yellore, VS | 1 |
He, D; Liu, F; Long, J; Matsuura, I; Wang, G | 1 |
Polhill, TS; Pollock, CA; Poronnik, P; Saad, S; Stanners, SR; Zafiriou, S | 1 |
Blakemore, AI; El Nahas, AM; Khalil, MS | 1 |
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N | 1 |
Azuma, H; Ehata, S; Horie, S; Imamura, T; Inamoto, T; Itoh, Y; Katsuoka, Y; Kiyama, S; Kiyama, Y; Maruyama, O; Miyazaki, H; Miyazono, K; Otsuki, Y; Sakamoto, T; Takahara, S; Ubai, T; Watabe, T | 1 |
Chen, L; Ge, Z; Gu, Y; Guo, L; Qi, M; Si, J; Yan, X; Yang, Y; Yu, P | 1 |
Manchanda, PK; Mittal, RD | 1 |
De Luca, F; Flint, JK; Rezvani, G; Wu, S | 1 |
Bhattacharya, SS; Bowling, BL; Ebenezer, ND; Filipec, M; Hardcastle, AJ; Jirsova, K; Klintworth, GK; Liskova, P; Tuft, SJ | 1 |
Fang, ZF; Li, XP; Liu, QM; Qiu, SF; Shen, XQ; Zhang, M; Zhao, SP; Zhou, SH | 1 |
Hao, A; Li, G; Ling, EA; Liu, S; Wang, F; Wang, J; Wang, L; Wang, Z; Yao, L; Yin, J; Zhang, X | 1 |
Chen, C; Guo, Y; Han, D; Hong, J; Ma, J; Okunieff, P; Wang, X; Yang, S; Zhang, B; Zhang, L; Zhang, M; Zhang, Z | 1 |
Ahmedat, AS; Juergens, UR; Kostenis, E; Mohr, K; Racké, K; Seemann, WK; Warnken, M | 1 |
Du, C; Lin, Y; Yang, J; Yang, Y | 1 |
Abdel Kawy, HS | 1 |
Ji, YW; Kim, EK; Kim, TI; Lee, J; Park, SY; Seo, KY | 1 |
Angelini, C; Blelloch, R; Cermola, F; Cobellis, G; D'Aniello, C; De Cesare, D; Di Napoli, G; Fico, A; Fiorenzano, A; Habibi, E; Melck, DJ; Minchiotti, G; Motta, A; Paris, D; Patriarca, EJ; Russo, F; Stunnenberg, HG | 1 |
Chen, X; Feng, H; Lu, JJ; Pei, L; Wang, Y | 1 |
Berisa, M; Cross, JR; Hendrickson, RC; Qin, W; Schwörer, S; Thompson, CB; Violante, S; Zhu, J | 1 |
74 other study(ies) available for proline and transforming growth factor beta
Article | Year |
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Transcriptional mechanisms of type I collagen gene expression are differentially regulated by interleukin-1 beta, tumor necrosis factor alpha, and transforming growth factor beta in Ito cells.
Topics: Animals; Blotting, Northern; Cell Nucleus; Cells, Cultured; Collagen; Extracellular Matrix; Gene Expression Regulation; Interleukin-1; Liver; Poly A; Proline; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1992 |
Modulation of cultured chicken growth plate chondrocytes by transforming growth factor-beta 1 and basic fibroblast growth factor.
Topics: Alkaline Phosphatase; Animals; Calcium; Cartilage; Cell Division; Cells, Cultured; Chickens; Collagen; Drug Interactions; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Fibronectins; Phosphates; Proline; Protein Biosynthesis; Tibia; Transforming Growth Factor beta | 1992 |
The effects of transforming growth factor-beta 1 on protein production by mouse embryonic palate mesenchymal cells in the presence or absence of serum.
Topics: Animals; Blood; Cell Division; Cells, Cultured; Collagen; Culture Media; Mesoderm; Mice; Palate; Plastics; Platelet-Derived Growth Factor; Proline; Protein Biosynthesis; Transforming Growth Factor beta | 1992 |
Synergistic effects of dexamethasone on platelet-derived growth factor mitogenesis in vitro.
Topics: Cell Division; Cells, Cultured; Collagen; Dental Pulp; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Gingiva; Humans; Insulin-Like Growth Factor I; Mitogens; Periodontal Ligament; Platelet-Derived Growth Factor; Proline; Prostaglandins E; Transforming Growth Factor beta | 1992 |
Effects of transforming growth factor-beta on collagen synthesis by normal rat kidney epithelial cells.
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Epithelial Cells; Epithelium; Kidney; Proline; Protein Biosynthesis; Rats; Transforming Growth Factor beta; Tritium | 1992 |
Growth factors modulate collagen production and collagenase action by skin fibroblasts in a dermal equivalent model system.
Topics: Cells, Cultured; Collagen; Fibroblasts; Humans; Infant, Newborn; Kinetics; Male; Microbial Collagenase; Platelet-Derived Growth Factor; Proline; Skin; Transforming Growth Factor beta | 1990 |
Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.
Topics: Animals; Antibodies; Cells, Cultured; Collagen; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Gene Expression; Glomerular Mesangium; Glucose; Immunoglobulin G; Mice; Mice, Inbred Strains; Proline; Protein Biosynthesis; Rabbits; Recombinant Proteins; Transforming Growth Factor beta | 1994 |
Collagen production in human lung fibroblasts in response to cytokines.
Topics: Cell Line; Collagen; DNA; Fibroblasts; Humans; Interleukin-1; Lung; Proline; Pulmonary Fibrosis; Transforming Growth Factor beta; Tritium | 1994 |
Rat mesangial cell hypertrophy in response to transforming growth factor-beta 1.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; DNA, Complementary; Gene Expression Regulation; Glomerular Mesangium; Hypertrophy; Leucine; Molecular Probes; Molecular Sequence Data; Proline; Rats; Receptors, Transforming Growth Factor beta; RNA, Messenger; Thymidine; Transforming Growth Factor beta | 1993 |
Effects of transforming growth factor-beta on collagen gene expression and collagen synthesis level in mineralizing cultures of osteoblast-like cell line, MC3T3-E1.
Topics: Animals; Cell Differentiation; Cell Line; Collagen; Gene Expression; Mice; Minerals; Osteoblasts; Proline; RNA, Messenger; Transforming Growth Factor beta | 1993 |
Refined crystal structure of human transforming growth factor beta 2 at 1.95 A resolution.
Topics: Amino Acid Sequence; Cysteine; Humans; Hydrogen Bonding; Ions; Models, Chemical; Molecular Sequence Data; Proline; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Transforming Growth Factor beta; Water; X-Ray Diffraction | 1993 |
Bone cell matrix promotes the adhesion of human prostatic carcinoma cells via the alpha 2 beta 1 integrin.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Bone and Bones; Carcinoma; Cell Adhesion; Cells, Cultured; Collagen; Extracellular Matrix; Humans; Integrin beta1; Male; Molecular Sequence Data; Osteoblasts; Osteosarcoma; Peptides; Phorbol Esters; Proline; Prostatic Neoplasms; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
A proline-rich TGF-beta-responsive transcriptional activator interacts with histone H3.
Topics: 3T3 Cells; Animals; Base Sequence; CCAAT-Enhancer-Binding Proteins; Chromatin; DNA-Binding Proteins; Gene Expression Regulation; Glutamine; Histones; Humans; Mice; Molecular Sequence Data; NFI Transcription Factors; Nucleosomes; Oligodeoxyribonucleotides; Point Mutation; Proline; Promoter Regions, Genetic; Transcription Factors; Transforming Growth Factor beta | 1995 |
TGF beta 1 alters the production of collagen types I and III by human gingival fibroblasts.
Topics: Cells, Cultured; Collagen; Edetic Acid; Ethylmaleimide; Fibroblasts; Gingiva; Humans; Phenylmethylsulfonyl Fluoride; Proline; Protease Inhibitors; Transforming Growth Factor beta; Tritium | 1996 |
Effects of peritoneal effluents on mesothelial cells in culture: cell proliferation and extracellular matrix regulation.
Topics: Adolescent; Ascitic Fluid; Cell Division; Cells, Cultured; Child; Collagen; Epithelium; Extracellular Matrix; Fibrosis; Humans; Interleukin-2; Peritoneal Dialysis; Peritoneum; Proline; RNA, Messenger; Thymidine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1996 |
Antagonistic regulation of a proline-rich transcription factor by transforming growth factor beta and tumor necrosis factor alpha.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Proteins; DNA-Binding Proteins; Down-Regulation; Histones; Mice; Molecular Sequence Data; NFI Transcription Factors; Oncogene Protein p21(ras); Oncogene Proteins v-raf; Proline; Retroviridae Proteins, Oncogenic; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1996 |
Effect of growth factors on matrix synthesis by ligament fibroblasts.
Topics: Analysis of Variance; Animals; Anterior Cruciate Ligament; Cells, Cultured; Collagen; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Extracellular Matrix; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblasts; Growth Substances; Proline; Protein Biosynthesis; Rabbits; Transforming Growth Factor beta; Tritium | 1997 |
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells.
Topics: Animals; Captopril; Cattle; Cells, Cultured; Coculture Techniques; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Mesangium; Glucose; Indoles; Maleimides; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Penicillamine; Proline; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transforming Growth Factor beta; Tritium | 1997 |
Ageing increases growth factor-induced inorganic pyrophosphate elaboration by articular cartilage.
Topics: Aging; Animals; Cartilage, Articular; Culture Media; Diphosphates; Epidermal Growth Factor; Growth Substances; Proline; Pyrophosphatases; Swine; Thymidine; Transforming Growth Factor beta | 1994 |
Transforming growth factor-beta-induced collagen synthesis by human liver myofibroblasts is inhibited by alpha2-macroglobulin.
Topics: alpha-Macroglobulins; Cells, Cultured; Collagen; Collagenases; Endocytosis; Fibroblasts; Humans; Liver; Proline; Protein Binding; Recombinant Proteins; Transforming Growth Factor beta | 1997 |
Human osteoblast response in vitro to platelet-derived growth factor and transforming growth factor-beta delivered from controlled-release polymer rods.
Topics: Biocompatible Materials; Carrier Proteins; Cell Differentiation; Cell Division; Cells, Cultured; Delayed-Action Preparations; Ethylenes; Hip Prosthesis; Humans; Isotope Labeling; Microscopy, Electron, Scanning; Osteoblasts; Platelet-Derived Growth Factor; Polymers; Proline; Protein Biosynthesis; Serum Albumin, Bovine; Thymidine; Transforming Growth Factor beta; Vinyl Compounds | 1997 |
Effects of hypertonic stress on transforming growth factor-beta activity in normal rat kidney cells.
Topics: Animals; Antibodies; Cell Line; Collagen; Fibroblasts; Hypertonic Solutions; Kidney; Proline; Rats; Reference Values; RNA, Messenger; Stress, Physiological; Transforming Growth Factor beta | 1998 |
Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women.
Topics: Adult; Aged; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genotype; Humans; Japan; Leucine; Middle Aged; Osteoporosis; Polymorphism, Genetic; Postmenopause; Proline; Protein Sorting Signals; Sequence Analysis, DNA; Transforming Growth Factor beta | 1998 |
Effects of proline cis-trans isomerization on TB domain secondary structure.
Topics: Fibrillin-1; Fibrillins; Humans; Isomerism; Magnetic Resonance Spectroscopy; Marfan Syndrome; Microfilament Proteins; Models, Molecular; Proline; Protein Conformation; Protein Structure, Secondary; Transforming Growth Factor beta | 1998 |
Requirement of a novel gene, Xin, in cardiac morphogenesis.
Topics: Amino Acid Sequence; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Chick Embryo; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation, Developmental; Heart; Homeobox Protein Nkx-2.5; Homeodomain Proteins; MEF2 Transcription Factors; Mice; Molecular Sequence Data; Morphogenesis; Muscle, Skeletal; Myogenic Regulatory Factors; Nuclear Proteins; Oligonucleotides, Antisense; Proline; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Somites; Species Specificity; Tissue Distribution; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Xenopus Proteins | 1999 |
Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells.
Topics: Animals; Antioxidants; Catalase; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Nucleus; Collagen; DNA-Binding Proteins; Genes, Reporter; Hydrogen Peroxide; Liver; Mice; Nuclear Proteins; Oxidants; Procollagen; Proline; Promoter Regions, Genetic; Rats; Response Elements; RNA, Messenger; Thiocarbamates; Transforming Growth Factor beta | 1999 |
Up-regulation by human recombinant transforming growth factor beta-1 of collagen production in cultured dermal fibroblasts is mediated by the inhibition of nitric oxide signaling.
Topics: Burns; Cells, Cultured; Cicatrix; Collagen; Cyclic GMP; Fibroblasts; Humans; Linear Models; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Proline; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 1999 |
Amyloid and Pro501 Thr-mutated (beta)ig-h3 gene product colocalize in lattice corneal dystrophy type IIIA.
Topics: Aged; Amyloid; Congo Red; Corneal Dystrophies, Hereditary; DNA; Exons; Extracellular Matrix Proteins; Humans; Immunoenzyme Techniques; Male; Neoplasm Proteins; Point Mutation; Polymerase Chain Reaction; Proline; Threonine; Transforming Growth Factor beta | 1999 |
Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-beta1 and TGF-beta3.
Topics: Blotting, Western; Cells, Cultured; Collagen; Collagenases; Extracellular Matrix; Fibroblasts; Gelatinases; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Metalloendopeptidases; Proline; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Tritium | 1999 |
Leu518Pro mutation of the beta ig-h3 gene causes lattice corneal dystrophy type I.
Topics: Adolescent; Adult; Base Sequence; Cornea; Corneal Dystrophies, Hereditary; DNA; Exons; Extracellular Matrix Proteins; Female; Humans; Keratoplasty, Penetrating; Leucine; Male; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Pedigree; Point Mutation; Proline; Transforming Growth Factor beta | 1999 |
Effects of TGFbeta2 on collagen synthesis in cultured normal and wounded fetal mouse palates.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Collagen; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Female; Fetus; Gestational Age; Immunohistochemistry; Mice; Mice, Inbred ICR; Palate; Proline; Transforming Growth Factor beta | 1999 |
Modulation of collagen synthesis by tumor necrosis factor alpha in cultured vascular smooth muscle cells.
Topics: Animals; Arteriosclerosis; Cattle; Cells, Cultured; Collagen; Humans; Muscle, Smooth, Vascular; Proline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2000 |
Stimulation of TGF-beta type II receptor by high glucose in mouse mesangial cells and in diabetic kidney.
Topics: Animals; Cells, Cultured; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Gene Expression; Glomerular Mesangium; Glucose; Mice; Mice, Inbred C57BL; Proline; Promoter Regions, Genetic; Receptors, Transforming Growth Factor beta; RNA Stability; RNA, Messenger; Transfection; Transforming Growth Factor beta | 2000 |
Association of a Leu(10)-->Pro polymorphism of the transforming growth factor-beta1 with genetic susceptibility to osteoporosis and spinal osteoarthritis.
Topics: Animals; Bone Density; Disease Susceptibility; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Osteoarthritis; Osteoporosis; Polymorphism, Genetic; Proline; Radius; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2000 |
Renal failure after clinical heart transplantation is associated with the TGF-beta 1 codon 10 gene polymorphism.
Topics: Adult; Cyclosporine; Female; Genotype; Heart Transplantation; Humans; Immunosuppressive Agents; Leucine; Male; Middle Aged; Polymorphism, Genetic; Proline; Renal Insufficiency; Sequence Analysis, DNA; Transforming Growth Factor beta | 2000 |
Transforming growth factor-beta(1) stimulates L-arginine transport and metabolism in vascular smooth muscle cells: role in polyamine and collagen synthesis.
Topics: Animals; Arginine; Biological Transport; Cells, Cultured; Muscle, Smooth, Vascular; Polyamines; Proline; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Effects of synthetic serine protease inhibitors on proliferation and collagen synthesis of human pancreatic periacinar fibroblast-like cells.
Topics: Cell Division; Cells, Cultured; Collagen; Esters; Fibroblasts; Gabexate; Guanidines; Humans; Pancreas; Platelet-Derived Growth Factor; Proline; Serine Proteinase Inhibitors; Thymidine; Transforming Growth Factor beta; Tritium | 2001 |
In vitro comparison of bioabsorbable and non-resorbable membranes in bone regeneration.
Topics: Absorbable Implants; Alkaline Phosphatase; Biocompatible Materials; Bone Regeneration; Cell Division; Cells, Cultured; Collagen; Culture Media, Conditioned; DNA; Enzyme-Linked Immunosorbent Assay; Guided Tissue Regeneration; Humans; Hyaluronic Acid; Materials Testing; Membranes, Artificial; Osteoblasts; Polyesters; Polytetrafluoroethylene; Proline; Radiopharmaceuticals; Statistics as Topic; Thymidine; Transforming Growth Factor beta; Tritium | 2001 |
The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker.
Topics: Adult; Age Factors; Alleles; Analysis of Variance; Arginine; Calcium Channel Blockers; Chi-Square Distribution; Codon; Confidence Intervals; Cyclosporine; DNA; Female; Gene Expression Regulation; Genotype; Gingival Overgrowth; Heterozygote; Homozygote; Humans; Immunosuppressive Agents; Kidney Transplantation; Leucine; Logistic Models; Male; Odds Ratio; Polymorphism, Genetic; Proline; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes.
Topics: Biological Transport; Cell Line; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Keratinocytes; Mitogen-Activated Protein Kinases; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; rac1 GTP-Binding Protein; Reactive Oxygen Species; Smad2 Protein; Thiocarbamates; Time Factors; Trans-Activators; Transforming Growth Factor beta | 2001 |
Transforming growth factor-beta 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression.
Topics: Amino Acid Transport System A; Animals; Biological Transport, Active; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Regulation; Kinetics; Muscle, Smooth, Vascular; Proline; Rats; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.
Topics: Activin Receptors, Type I; Animals; Benzamides; Cell Differentiation; Cells, Cultured; Collagen Type IV; Diabetic Nephropathies; Dioxoles; Drug Synergism; Endothelial Growth Factors; Gene Expression; Glucose; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Lymphokines; Mice; Proline; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells.
Topics: Adenoviridae; Antibodies, Blocking; Blotting, Northern; Blotting, Western; Cells, Cultured; Connective Tissue Growth Factor; Epithelial Cells; Fibrosis; Genetic Vectors; Glomerular Mesangium; Growth Substances; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Tubules, Proximal; Luciferases; Plasmids; Proline; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Transforming Growth Factor beta | 2002 |
TGF-beta stimulates collagen (I) in vascular smooth muscle cells via a short element in the proximal collagen promoter.
Topics: Binding Sites; Blotting, Northern; Cell Nucleus; Chromosome Mapping; Collagen; Collagen Type I; DNA; Humans; Luciferases; Muscle, Smooth, Vascular; Proline; Promoter Regions, Genetic; Recombinant Proteins; Response Elements; RNA, Messenger; Transfection; Transforming Growth Factor beta; Tritium | 2003 |
No association between the TGF-beta 1 Leu10Pro polymorphism and osteoporosis among white women in the United States.
Topics: Aged; Amino Acid Sequence; Bone Density; Cohort Studies; Female; Fractures, Bone; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Multivariate Analysis; Osteoporosis; Polymorphism, Genetic; Proline; Proportional Hazards Models; Risk Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; United States; White People | 2003 |
Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Base Sequence; Chi-Square Distribution; Codon; Confidence Intervals; Disease Progression; Female; Follow-Up Studies; Gene Frequency; Genotype; Humans; Linear Models; Male; Oxygen; Polymorphism, Genetic; Proline; Pulmonary Alveoli; Pulmonary Fibrosis; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.
Topics: Amino Acid Substitution; Breast Neoplasms; Case-Control Studies; HeLa Cells; Humans; Leucine; Neoplasm Invasiveness; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Promoter Regions, Genetic; Protein Sorting Signals; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Genetic factors in idiopathic pulmonary fibrosis: transforming growth factor-beta implicated at last.
Topics: Animals; Codon; Disease Models, Animal; Disease Progression; Exons; Humans; Polymorphism, Genetic; Proline; Pulmonary Fibrosis; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.
Topics: Albuminuria; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Blotting, Western; Cells, Cultured; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Fibroblasts; Fibronectins; Fibrosis; Humans; Immunohistochemistry; Kidney; Mice; ortho-Aminobenzoates; Proline; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Time Factors; Transforming Growth Factor beta; Tritium | 2003 |
Short-term peaks in glucose promote renal fibrogenesis independently of total glucose exposure.
Topics: Blood Glucose; Cells, Cultured; Collagen Type IV; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Glucose; Humans; Kidney; Kidney Cortex; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Proline; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Ursolic acid, an antagonist for transforming growth factor (TGF)-beta1.
Topics: Animals; BALB 3T3 Cells; Cell Division; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Humans; Lung; Mice; Mink; Models, Molecular; Proline; Radioligand Assay; Recombinant Proteins; Thymidine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid | 2004 |
Cyclic strain stimulates L-proline transport in vascular smooth muscle cells.
Topics: Amino Acid Transport System A; Animals; Aorta, Thoracic; Autocrine Communication; Blood Pressure; Cells, Cultured; Hypertension; Muscle, Smooth, Vascular; Proline; Rats; RNA, Messenger; Stress, Mechanical; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor.
Topics: Blotting, Northern; Blotting, Western; Bone Morphogenetic Protein Receptors, Type I; Cell Line; Cell Nucleus; Cloning, Molecular; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Complementary; Genes, Reporter; Homeodomain Proteins; Humans; Immunoprecipitation; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Growth Factor; RNA Splicing; RNA Splicing Factors; RNA-Binding Proteins; Saccharomyces cerevisiae; Signal Transduction; Tissue Distribution; Transfection; Transforming Growth Factor beta; Two-Hybrid System Techniques | 2004 |
Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene.
Topics: Adult; Alanine; Amyloid; Amyloidosis; Aspartic Acid; Cornea; Corneal Dystrophies, Hereditary; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Female; Glutamine; Haplotypes; Humans; Mutation, Missense; Pedigree; Proline; Transforming Growth Factor beta | 2004 |
The Smad3 linker region contains a transcriptional activation domain.
Topics: Adenovirus E1A Proteins; Animals; Binding Sites; Cells, Cultured; DNA; DNA-Binding Proteins; Genes, Reporter; Humans; Mammals; Nuclear Proteins; Proline; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Smad3 Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation; Transfection; Transforming Growth Factor beta | 2005 |
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts.
Topics: Cell Death; Cell Division; Collagen Type IV; Extracellular Matrix; Fibroblasts; Fibronectins; Gene Expression; Glucose; Humans; Hypoglycemic Agents; In Vitro Techniques; Kidney Cortex; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pioglitazone; PPAR gamma; Proline; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Transforming growth factor-beta1 SNPs: genetic and phenotypic correlations in progressive kidney insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Cytosine; Disease Progression; Female; Fibrosis; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glomerulosclerosis, Focal Segmental; Haplotypes; Homozygote; Humans; Immunohistochemistry; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Proline; Severity of Illness Index; Staining and Labeling; Thymine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2005 |
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.
Topics: Adenoviridae; Alanine; Animals; Arginine; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins; DNA, Complementary; Female; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Glycine; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Mutagenesis, Insertional; Neoplasm Invasiveness; Polymerase Chain Reaction; Proline; Proto-Oncogene Proteins; Repressor Proteins; Signal Transduction; Smad6 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation | 2005 |
A clinical and molecular-genetic analysis of Chinese patients with lattice corneal dystrophy and novel Thr538Pro mutation in the TGFBI (BIGH3) gene.
Topics: China; Corneal Dystrophies, Hereditary; Female; Humans; Male; Mutation; Pedigree; Polymerase Chain Reaction; Proline; Threonine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Is low-frequency distribution of TGF-beta genotype associated with increased risk for end-stage renal disease?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Codon; Female; Genotype; Haplotypes; Humans; Kidney Failure, Chronic; Linkage Disequilibrium; Male; Middle Aged; Nephritis; Polymorphism, Genetic; Proline; Risk; Transforming Growth Factor beta | 2007 |
Nuclear factor-kappaB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis.
Topics: Animals; Apoptosis; Bone and Bones; Bone Development; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Caspase 3; Cell Differentiation; Cell Proliferation; Chondrocytes; In Situ Hybridization; Models, Biological; Proline; Rats; Rats, Sprague-Dawley; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta | 2007 |
Phenotype associated with the H626P mutation and other changes in the TGFBI gene in Czech families.
Topics: Adult; Amyloid; Cataract; Cornea; Corneal Dystrophies, Hereditary; Czech Republic; Extracellular Matrix Proteins; Female; Histidine; Humans; Male; Middle Aged; Mutation; Phenotype; Proline; Transforming Growth Factor beta | 2008 |
Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.
Topics: Antioxidants; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Nucleus; Cells, Cultured; Cytoplasm; Down-Regulation; Drug Interactions; Endothelial Cells; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Malondialdehyde; Proline; Pyrroles; RNA, Messenger; Superoxide Dismutase; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta; Umbilical Veins | 2008 |
High glucose-induced expression of inflammatory cytokines and reactive oxygen species in cultured astrocytes.
Topics: Animals; Astrocytes; Blotting, Western; Cell Survival; Cells, Cultured; Cytokines; Free Radical Scavengers; Glucose; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-4; Interleukin-6; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Proline; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA; STAT3 Transcription Factor; Thiocarbamates; Transforming Growth Factor beta; Triterpenes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2012 |
In vitro Sirius Red collagen assay measures the pattern shift from soluble to deposited collagen.
Topics: Animals; Antineoplastic Agents, Alkylating; Azo Compounds; Biological Assay; Cells, Cultured; Collagen; Coloring Agents; Diterpenes; Embryo, Mammalian; Epoxy Compounds; Fetus; Fibroblasts; Humans; Lung; Mice; NIH 3T3 Cells; Phenanthrenes; Proline; Transforming Growth Factor beta | 2013 |
Pro-fibrotic processes in human lung fibroblasts are driven by an autocrine/paracrine endothelinergic system.
Topics: Cell Line; Cells, Cultured; Collagen; Endothelin Receptor Antagonists; Endothelins; Fibroblasts; Fibrosis; Humans; Lung; Male; Proline; Protein Isoforms; Receptors, Endothelin; Thymidine; Transforming Growth Factor beta | 2013 |
Expression and mechanism of BRP-39 in bleomycin-induced pulmonary fibrosis in rat.
Topics: Animals; Bleomycin; Chitinase-3-Like Protein 1; Gene Expression Regulation; Glycoproteins; Male; Mice; Mice, Inbred C57BL; Proline; Pulmonary Fibrosis; Transforming Growth Factor beta | 2014 |
Cilostazol attenuates cholestatic liver injury and its complications in common bile duct ligated rats.
Topics: Actins; Animals; Cholestasis; Cilostazol; Common Bile Duct; Dose-Response Relationship, Drug; Hemoglobins; Ligation; Liver; Liver Cirrhosis; Male; Neovascularization, Pathologic; Portal Pressure; Proline; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
Delayed Onset of Lattice Corneal Dystrophy Type IIIA Due to a Novel T621P Mutation in TGFBI.
Topics: Adult; Cornea; Corneal Dystrophies, Hereditary; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Female; Humans; Male; Middle Aged; Pedigree; Point Mutation; Proline; Threonine; Tomography, Optical Coherence; Transforming Growth Factor beta; Visual Acuity | 2016 |
Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum.
Topics: Animals; Ascorbic Acid; Cell Differentiation; Cell Self Renewal; Cluster Analysis; DNA Methylation; Fibroblast Growth Factors; Gene Expression Profiling; Metabolome; Metabolomics; Mice; MicroRNAs; Pluripotent Stem Cells; Proline; Signal Transduction; Transforming Growth Factor beta | 2017 |
Osthole inhibited TGF β-induced epithelial-mesenchymal transition (EMT) by suppressing NF-κB mediated Snail activation in lung cancer A549 cells.
Topics: A549 Cells; Cadherins; Coumarins; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; NF-kappa B; Proline; Snail Family Transcription Factors; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta | 2017 |
Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
Topics: Animals; Citric Acid Cycle; Collagen; Energy Metabolism; Fibrosis; Glucose; Glutamine; Humans; Mice; Mitochondria; NIH 3T3 Cells; Oxidation-Reduction; Oxidative Phosphorylation; Proline; Reactive Oxygen Species; Transforming Growth Factor beta | 2020 |