proline has been researched along with sirolimus in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 7 (30.43) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Brunn, GJ; Fadden, P; Haystead, TA; Lawrence, JC | 1 |
| Demain, AL; Griffith, S; Kojima, I; Wong, GK | 1 |
| Filonenko, V; Gout, I; Hara, K; Minami, T; Tsujishita, Y; Waterfield, MD; Yonezawa, K | 1 |
| Bussolati, O; Dall'Asta, V; Franchi-Gazzola, R; Gazzola, GC; Visigalli, R | 1 |
| Cooper, TG; van der Merwe, GK; van Vuuren, HJ | 1 |
| Carlier, MF; Castellano, F; Chavrier, P; Le Clainche, C; Patin, D | 1 |
| Kupferwasser, D; Lam, J; Lee-Fruman, KK; Phin, S | 1 |
| Brandriss, MC; Kannan, KB; Saxena, D | 1 |
| Crespo, JL; Demougin, P; Fowler, B; Hall, MN; Helliwell, SB; Primig, M; Wiederkehr, C | 1 |
| Dubois, E; Feller, A; Messenguy, F; Scherens, B; Vierendeels, F | 1 |
| Cooper, TG; Tate, JJ | 1 |
| Huang, X; Kimmel, AR; Liao, XH; Majithia, A | 1 |
| Cooper, SK; Donald, SP; Pandhare, J; Phang, JM | 1 |
| Campbell, RN; Connolly, Y; Leverentz, MK; Reece, RJ; Whetton, AD | 1 |
| Miltyk, W; Palka, J; Prokop, I; Surazynski, A | 1 |
| Antonini, TM; Barau, C; Bonhomme-Faivre, L; Coilly, A; Duclos-Vallée, JC; Furlan, V; Noël, C; Roche, B; Roque-Afonso, AM; Samuel, D; Taburet, AM | 1 |
| Mizuno, S; Nakamura, T; Ohya-Shimada, W; Oka, K | 1 |
| Hall, MN; Jozefczuk, S; Rudroff, F; Sauer, U; Stracka, D | 1 |
| Chu, TL; Du, C; Guan, Q; Nguan, CY | 1 |
| Chen, X; Jin, D; Sun, J; Yang, Z; Yu, A; Yu, X | 1 |
| Dolman, GE; Gelson, WT; Selby, P | 1 |
| Brown, RS; Chen, JK; Hedvat, J; Jennings, DL; Kovac, DB; Lange, NW; Pereira, MR; Salerno, DM; Scheffert, J; Shertel, T | 1 |
1 review(s) available for proline and sirolimus
| Article | Year |
|---|---|
Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arabidopsis Proteins; Dictyostelium; Models, Biological; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sequence Homology, Amino Acid; Signal Transduction; Sirolimus; Tacrolimus Binding Protein 1A; Transcription Factors | 2008 |
22 other study(ies) available for proline and sirolimus
| Article | Year |
|---|---|
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus.
Topics: Amino Acid Sequence; Animals; Antibodies; Binding Sites; Carrier Proteins; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Polyenes; Proline; Rats; Serine; Sirolimus; Substrate Specificity; Threonine | 1997 |
Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Fusarium; Microbial Sensitivity Tests; Molecular Structure; Polyenes; Proline; Saccharomyces cerevisiae; Sirolimus | 1998 |
Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region.
Topics: Amino Acid Sequence; Androstadienes; Animals; Blotting, Northern; Catalytic Domain; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Enzyme Inhibitors; Humans; Molecular Sequence Data; Open Reading Frames; Peptide Mapping; Phosphorylation; Proline; Ribosomal Protein S6 Kinases; Sirolimus; Wortmannin | 1998 |
Adaptive increase of amino acid transport system A requires ERK1/2 activation.
Topics: Amino Acids; Androstadienes; beta-Alanine; Biological Transport; Carrier Proteins; Cell Size; Culture Media; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Hypertonic Solutions; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Sirolimus; Wortmannin | 1999 |
Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.
Topics: Ammonia; Cell Nucleus; DNA-Binding Proteins; Fungal Proteins; GATA Transcription Factors; Gene Deletion; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Nitrogen; Proline; Protein Transport; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors; Transcription, Genetic; Vesicular Transport Proteins | 2001 |
A WASp-VASP complex regulates actin polymerization at the plasma membrane.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Animals; Biopolymers; Cell Adhesion Molecules; Cell Line; Cell Movement; Cricetinae; Cytoskeletal Proteins; Dimerization; Fluorescent Antibody Technique; Kidney; Leukemia, Basophilic, Acute; Ligands; Macromolecular Substances; Mast Cells; Membrane Proteins; Mesocricetus; Microfilament Proteins; Multigene Family; Phagocytosis; Phosphoproteins; Proline; Protein Structure, Tertiary; Proteins; Rats; Receptors, Interleukin-2; Recombinant Fusion Proteins; Sirolimus; Structure-Activity Relationship; Tacrolimus Binding Proteins; Transfection; Tumor Cells, Cultured; Wiskott-Aldrich Syndrome Protein | 2001 |
Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Antineoplastic Agents; Cells, Cultured; Humans; Immunosuppressive Agents; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Proline; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Sirolimus; Threonine; Transfection; Wortmannin | 2003 |
Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae.
Topics: Gene Expression Regulation, Fungal; Genes, Fungal; Immunosuppressive Agents; Models, Biological; Mutation; Nitrogen; Phosphoproteins; Phosphorylation; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Trans-Activators; Transcription Factors | 2003 |
NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.
Topics: Adaptor Proteins, Signal Transducing; Endosomal Sorting Complexes Required for Transport; Nitrogen; Proline; Protein Kinases; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors; Transcription, Genetic; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases | 2004 |
Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term.
Topics: Binding Sites; GATA Transcription Factors; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glutamine; Glutathione Peroxidase; Nitrogen; Oligonucleotide Array Sequence Analysis; Prions; Proline; Promoter Regions, Genetic; Repressor Proteins; Ribosomal Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors | 2006 |
Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation.
Topics: Carbon; Cell Nucleus; Cytoplasm; Gene Expression Regulation, Fungal; Glutamine; Methionine Sulfoximine; Models, Biological; Nitrogen; Phosphorylation; Proline; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus; Sodium Chloride; Transcription Factors | 2007 |
Regulation and function of proline oxidase under nutrient stress.
Topics: Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; Glucose; Humans; Malnutrition; Proline; Proline Oxidase; Sirolimus; Stress, Physiological; Up-Regulation | 2009 |
Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner.
Topics: Antifungal Agents; GATA Transcription Factors; Gene Expression Regulation, Fungal; Mutation; Phosphorylation; Proline; Proline Oxidase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors; Transcription, Genetic | 2009 |
Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.
Topics: Cells, Cultured; Dipeptidases; Down-Regulation; Fibroblasts; Humans; Hydroxyproline; Osmolar Concentration; Phosphoenolpyruvate; Phosphorylation; Proline; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Sirolimus; Skin; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1; Up-Regulation | 2010 |
Practical management of boceprevir and immunosuppressive therapy in liver transplant recipients with hepatitis C virus recurrence.
Topics: Aged; Antiviral Agents; Cyclosporine; Disease Management; Drug Therapy, Combination; Everolimus; Hepacivirus; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Liver Transplantation; Male; Middle Aged; Polyethylene Glycols; Proline; Recombinant Proteins; Recurrence; Ribavirin; Sirolimus; Tacrolimus; Viral Load | 2012 |
Up-regulation of cyclin-E(1) via proline-mTOR pathway is responsible for HGF-mediated G(1)/S progression in the primary culture of rat hepatocytes.
Topics: Animals; Blotting, Western; Cell Cycle; Cells, Cultured; Collagen; Cyclin E; Cyclins; DNA; Dose-Response Relationship, Drug; G1 Phase; Gene Expression; Hepatocyte Growth Factor; Hepatocytes; Male; Phosphorylation; Proline; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6; S Phase; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Up-Regulation | 2013 |
Nitrogen source activates TOR (target of rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins.
Topics: Ammonium Compounds; Glutamine; Immunoblotting; Leucine; Methionine Sulfoximine; Monomeric GTP-Binding Proteins; Mutation; Nitrogen; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors | 2014 |
Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells.
Topics: Animals; Blotting, Western; Cell Death; Cell Proliferation; Cells, Cultured; Cyclosporine; Drug Synergism; Epithelial Cells; Flow Cytometry; Humans; Kidney Tubules; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Piperidines; Proline; Quinazolinones; Receptors, Antigen, T-Cell; Sirolimus; T-Lymphocytes | 2015 |
p65 down-regulates DEPTOR expression in response to LPS stimulation in hepatocytes.
Topics: Animals; Cell Line; Chemokine CCL2; Gene Expression Regulation; HEK293 Cells; Hepatitis, Animal; Hepatocytes; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Liver; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Multiprotein Complexes; Mutation; NF-KappaB Inhibitor alpha; Proline; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sirolimus; Thiocarbamates; TOR Serine-Threonine Kinases; Transcription Factor RelA; Transcription, Genetic | 2016 |
Ombitasvir/paritaprevir/ritonavir plus dasabuvir regimen may be used safely in combination with sirolimus for the treatment of chronic hepatitis C.
Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; End Stage Liver Disease; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Transplantation; Macrocyclic Compounds; Male; Proline; Ritonavir; Sirolimus; Sulfonamides; Treatment Outcome; Uracil; Valine | 2018 |
Early clinical experience with nirmatrelvir/ritonavir for the treatment of COVID-19 in solid organ transplant recipients.
Topics: Adult; Calcineurin Inhibitors; COVID-19 Drug Treatment; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Lactams; Leucine; Nitriles; Organ Transplantation; Proline; Retrospective Studies; Ritonavir; Sirolimus; Tacrolimus; Transplant Recipients | 2022 |