proline has been researched along with serine in 868 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 355 (40.90) | 18.7374 |
| 1990's | 165 (19.01) | 18.2507 |
| 2000's | 206 (23.73) | 29.6817 |
| 2010's | 112 (12.90) | 24.3611 |
| 2020's | 30 (3.46) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Bartnik, E; Piotrowska, M; Stepień, PP; Zakrzewska, E | 1 |
| Cann, JR; London, RE; Matwiyoff, NA; Stewart, JM | 1 |
| Kilroe-Smith, TA; McLoughlin, JL | 1 |
| Kawai, T; Takagi, K | 1 |
| Barrell, BG; McClain, WH; Seidman, JG | 1 |
| Mayhall, CW | 1 |
| Choih, S; Schachtele, CF; Smith, QT | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Buianovskaia, EA; Gordeev, VK | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 2 |
| Borghetti, AF; Guidotti, GG; Tramacere, M | 1 |
| Dahlberg, L; Schuberth, J | 1 |
| Bailey, RS; Fried, B | 1 |
| Feldman, H | 1 |
| Anda, LP; Dotchev, D; Liappis, N | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Bayley, HS; Chavez, ER | 1 |
| Harada, K; Iwaki, T; Koyama, Y; Oyama, S; Uchida, H | 1 |
| Counahan, R; Cox, BD; El-Bishti, M; Ogg, CS | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Rytka, J | 1 |
| McClain, WH; Seidman, JG | 1 |
| Lee, M; Oxender, DL; Robbins, JC | 1 |
| Foss, K; McClain, WH; Schmidt, FJ; Seidman, JG | 1 |
| Schmidt, FJ | 1 |
| Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Bennick, A | 1 |
| Bell, JR; Jones, JH; Webb, TC | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Kester, AS; Mayfield, DC | 1 |
| Benassi, CA; Guggi, A; Rocchi, R; Salvadori, S; Tomatis, R | 1 |
| Claybrook, DL | 1 |
| Bonduelle, M; Dab, I; Liebaers, I; Lissens, W; Malfroot, A | 1 |
| Burbaum, JJ; Schimmel, P | 1 |
| Jaenicke, R; Risse, B; Rudolph, R; Schumacher, G; Stempfer, G | 1 |
| Chaffotte, A; Lascu, I; Limbourg-Bouchon, B; Véron, M | 1 |
| Arnebrant, T; Glantz, PO; Rundegren, J; Vassilakos, N | 1 |
| Igarashi, K; Imaizumi, R; Kobayashi, H; Ohyama, T | 1 |
| Boutron, A; Goenner, S; Lemonnier, A; Moatti, N; Soni, T | 1 |
| Akino, T; Konno, R; Nagata, Y; Shimojo, T; Yamamoto, K; Yasumura, Y | 1 |
| Bowne, DB; Flores, E; Matthews, RJ; Thomas, ML | 1 |
| Forstner, G; Forstner, J; Huan, LJ; Xu, G | 1 |
| Lang, E; Otvos, L | 1 |
| Azziz, R; Ballard, AL; Owerbach, D; Sherman, L | 1 |
| Akino, T; Masui, R; Nagata, Y | 1 |
| Caen, JP; Chen, YP; Cieutat, AM; Djaffar, I; Pidard, D; Rosa, JP; Steiner, B | 1 |
| Nagata, Y; Shimojo, T; Yamamoto, K | 1 |
| Cooper, DN; Grundy, CB; Holding, S; Kakkar, VV; Millar, DS | 1 |
| Berling, B; Biernat, J; Goedert, M; Lichtenberg-Kraag, B; Mandelkow, E; Mandelkow, EM; Mercken, M; Meyer, H; Schröter, C; Steiner, B; Vandermeeren, A | 1 |
| Hofsteenge, J; Rennex, D; Shaw, E; Stone, SR; Wikstrom, P | 1 |
| Glenn, JS; Havel, CM; Watson, JA; White, JM | 1 |
| Flickinger, CJ; Herr, JC; Klotz, K; Shannon, J; Wright, RM | 1 |
| Biernat, J; Goedert, M; Gustke, N; Mandelkow, E; Mandelkow, EM; Meyer, HE; Steiner, B | 1 |
| Rykke, M; Sönju, T | 1 |
| Suzuki, M; Yagi, N | 1 |
| Adams, EM; Atkinson, JP; Liszewski, MK; Miller, EA; Post, TW; Tedja, I | 1 |
| Harikrishna, JA; Jones, KL; Lin, D; Miller, WL; Moore, CC | 1 |
| Dibrov, PA | 1 |
| Carrell, RW; Daly, M; Harper, PL; Perry, DJ; Price, J; Tait, RC; Walker, ID | 1 |
| Classon, BJ; Gooley, AA; Marschalek, R; Williams, KL | 1 |
| Amioka, H; Dojo, S; Hayashi, K; Hiraoka, M; Hirata, Y; Kurushima, H; Nakashima, K; Nishio, E; Ohtani, H; Saeki, M | 1 |
| Aguirre, J; Arteman, P; Brandariz, S; del Castillo, E; Silberstein, C; Uranga, J | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Basheer, R; Iordanescu, S | 1 |
| Lamb, RA; Simpson, DA | 1 |
| Kim, PS; Lin, TY | 1 |
| Sotiroudis, TG; Xenakis, A | 1 |
| Fukumaki, Y; Inoue, J; Kobayashi, Y; Sakaki, Y; Yubisui, T | 1 |
| Guillette, RA; Johnson, MH; Jue, DL; McDonald, MJ; Michalski, LA; Moo-Penn, WF; Turci, SM | 1 |
| Dobbins, DE; Premen, AJ | 1 |
| Mason, JI; Mathew, PA; Sanders, D; Trant, JM; Waterman, MR | 1 |
| Lisowsky, T; Michaelis, G; Riemen, G | 1 |
| Goldberg, M; Lecolle, S; Roche, M; Salomon, JP; Septier, D | 1 |
| Bertina, RM; Coenen, J; Deutz-Terlouw, PP; Leemhuis, MP; Ploos van Amstel, HK; Reitsma, PH; van der Linden, IK; van Wijngaarden, A | 1 |
| Inoue, M; Ishiura, M; Iwai, K; Kaneda, Y; Koide, T; Okada, Y; Uchida, T | 1 |
| Premen, AJ | 1 |
| Suzuki, M | 1 |
| Hundal, HS; Rennie, MJ; Watt, PW | 1 |
| Aviv, D; Edelman, M; Fromm, H; Galili, S; Galun, E | 1 |
| Hattman, S; Miner, Z; Schlagman, SL | 1 |
| Algermissen, B; Hampl, H; Nündel, M; Riedel, E; Scigalla, P; Stabell, U | 1 |
| Christoph, G; Siman, R | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Rechsteiner, M; Rogers, S; Wells, R | 1 |
| Cain, BD; Chun, KT; Simoni, RD; Vik, SB | 1 |
| Rechsteiner, M | 1 |
| Futai, M; Shiota, S; Tsuchiya, T; Yazyu, H | 1 |
| Bârzu, O; Fermandjian, S; Gilles, AM; Michelson, S; Monnot, M; Saint-Girons, I | 1 |
| Arme, C; Jeffs, SA | 1 |
| Conlon, JM; Shaw, C; Thim, L | 1 |
| Beertsen, W; Niehof, A | 1 |
| Corriat, A; Feneant-Thibault, M; Lemonnier, A; Maccario, J; Moatti, N | 1 |
| Christensen, HN; Flickinger, KS; Pisoni, RL; Thoene, JG | 1 |
| Bradley, TJ; Garrett, MA | 1 |
| Dziewiatkowski, DD; Lucas, PA | 1 |
| Isenman, DE; Painter, RH; Shulman, MJ; Wright, JF | 1 |
| Inage, T; Toda, Y | 1 |
| Brandt-Rauf, PW; Pincus, MR | 1 |
| Glimcher, MJ; Strawich, E | 1 |
| Asmerom, Y; Lee, T; Louis, J; Rahbar, S | 1 |
| Kelly, B; Levy, JG | 1 |
| Itano, HA; Kawasaki, I | 1 |
| Bryce, GF | 1 |
| De Lorenzo, F; Givol, D | 1 |
| Jones, GH; Weissbach, H | 1 |
| Qadri, SM; Williams, RP | 1 |
| Banerjee, AB; Bhattacharyya, SK | 1 |
| Cifonelli, JA; Mathews, MB | 1 |
| Bray, BA; Lieberman, R; Meyer, K | 1 |
| Nemoto, T; Yosizawa, Z | 1 |
| Kritcher, EM; Luchi, RJ; Thyrum, PT | 1 |
| Funatsu, G; Nierhaus, K; Wittmann-Liebold, B | 1 |
| Hong, JS; Lieberman, MA | 1 |
| Brown, EG; Silver, AV | 1 |
| Baranova, AM; Bragina, MP; Moroz, AF | 1 |
| Borghetti, AF; Guidotti, GG; Lüneburg, B | 1 |
| Froncish, W; Kalmanson, AE; Kharitonenkov, IG; Yuferov, VP | 1 |
| Erikson, E; Erikson, RL | 1 |
| Berry, SA; Campbell, JN; Johnson, KG | 1 |
| Erbe, RW; Krane, SM; Pinnell, SR | 1 |
| Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Medvedev, SA | 1 |
| Hogan, BL; Murden, S | 1 |
| Kaback, HR; Lombardi, FJ; Reeves, JP; Short, SA | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Margoliash, E; Putterman, GJ; Sherman, F | 1 |
| Casey, JW; Getz, GS; Hsu, HJ; Rabinowitz, M | 1 |
| Chandra, P; Lingens, F; Süssmuth, R; Wacker, A | 1 |
| Heidemann, E; Nill, HW | 2 |
| Abeles, RH; Schonbrunn, A; Walsh, CT | 1 |
| Kuhn, J; Somerville, RL | 1 |
| Lewis, GP; McMartin, C; Rosenthal, SR; Yates, C | 1 |
| Ragnarsson, U; Sandberg, BE | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Dancis, J; Schneider, H | 1 |
| Crossley, AC; Evans, PD | 1 |
| el-Sewefy, AZ; Hegazi, SM | 1 |
| Anandaraj, MP; Cherayil, JD | 1 |
| Arai, T; Ichishima, E | 1 |
| Gold, DV; Miller, F | 1 |
| Davis, SR; Mepham, TB | 1 |
| Friedmann, N; Miller, SL; Ring, D; Wolman, Y | 1 |
| Dorfman, A; Nevo, Z | 1 |
| Altman, S; Barrell, BG; Guthrie, C; McClain, WH; Seidman, JG; Smith, JD | 1 |
| Barrell, BG; Guthrie, C; McClain, WH; Seidman, JG | 1 |
| Allen, A; Snary, D | 1 |
| Adler, J; Mesibov, R | 1 |
| Melamed, MD | 1 |
| Nair, RM; Schally, AV | 1 |
| Arimura, A; Hashimoto, T; Kaneko, T; Schally, AV; Tsuji, K; Yanaihara, C; Yanihara, N | 1 |
| Miller, EJ | 1 |
| Sunde, ML | 1 |
| Fuchs, S; Inouye, H; Littauer, UZ; Sela, M | 1 |
| Isenberg, S; Newman, EB | 1 |
| Musial, M | 1 |
| Ozeki, H; Sakano, H; Shimura, Y | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Flory, B; Krassner, SM | 2 |
| Albers, RJ; DeTar, DF; Gilmore, F | 1 |
| Baker, DH; Boomgaardt, J | 1 |
| Desmarais, M; Pare, JP | 1 |
| Evered, DF | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Ando, T; Suzuki, K | 2 |
| Okano, T; Sato, Y | 1 |
| Leblond, CP; Weinstock, M | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Hochstrasser, K; Münzel, M | 1 |
| Gruber, L; Harris, JE | 1 |
| Peterson, NA; Raghupathy, E | 2 |
| Agarwala, SC; Rastogi, AK; Sagar, P | 1 |
| Harrap, BS; Heidemann, ER; Schiele, HD | 1 |
| Holme, T; Wahren, A | 1 |
| De Loecker, W; Stas, ML | 1 |
| Herbert, JD | 1 |
| Trayhurn, P; van Heyningen, R | 1 |
| Cole, RD; Colom, J; Cozcolluela, C; Phelan, JJ; Subirana, JA | 1 |
| Fridkin, M; Goren, HJ | 1 |
| Jörnvall, H; Ohlsson, H; Philipson, L | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Chapeville, F; Chousterman, S; Hervé, G | 1 |
| Lin, YC; Tanaka, N | 1 |
| Sakiyama, F | 1 |
| Milstein, CP | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Ekert, B; Monier, R; Tordjman, A | 1 |
| Arnold, RL; Kakade, ML; Liener, IE; Waibel, PE | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Cerná, J; Chládek, S; Pulkrábek, P; Rychlík, I; Zemlicka, J | 1 |
| Fraenkel-Conrat, H; Singer, B | 1 |
| Gott, CL; Qadri, SM; Williams, RP | 1 |
| Dunlap, BE; Friderici, KH; Rottman, F | 1 |
| Arimura, A; Baba, Y; Matsuo, H; Nair, RM; Schally, AV | 1 |
| Degens, ET; Matheja, J | 1 |
| Hunt, DE | 2 |
| Glenner, GG; Nagatsu, I; Nagatsu, T | 1 |
| Dolif, D; Jürgens, P | 2 |
| Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
| Gronlund, AF; Kay, WW | 1 |
| Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
| Bourrillon, R; Jouanneau, J; Razafimahaleo, E | 1 |
| Jamieson, GA; Pepper, DS | 1 |
| Horowitz, MI; Kim, YS | 1 |
| Blout, ER; Brown, FR; Di Corato, A; Lorenzi, GP | 1 |
| Hewitt, D; Lewis, D | 1 |
| Boling, JA; Bradley, NW; Willard, JC | 1 |
| Fujita, S | 1 |
| Ahonen, J; Mäenpää, PH | 1 |
| Clark, KG; Lehmann, H; Lorkin, PA; Wiltshire, BG | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Ono, T; Tasaki, I | 1 |
| Craft, IL; Peters, TJ | 1 |
| Carmichael, DK; Veis, A; Wang, ET | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Shearer, TR; Suttie, JW | 1 |
| Borghetti, AF; Gazzola, GC; Guidotti, GG; Lüneburg, B | 1 |
| Mead, GC | 1 |
| Christensen, HN; Koser, BH | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Barooshian, AV; Harris, WG; Lautenschleger, MJ | 1 |
| Ermol'eva, ZV; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA | 1 |
| Markussen, J | 1 |
| Gold, MB; Reynold, JM; Scriver, CR | 1 |
| Kabat, EA | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Gallo, RC; Pestka, S | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| Jones, OW; Nirenberg, MW | 1 |
| Appella, E; Martin, RG; Voll, MJ | 1 |
| Betuel, H; Colobert, L; Richard, G | 1 |
| Kathan, RH; Weeks, DI | 1 |
| Cepurneek, CP; Davis, PS; Multani, JS; Saltman, P | 1 |
| Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
| Gordon, WG; Groves, ML | 1 |
| Chen, DM; Harper, AE; Rogers, QR | 1 |
| Cooper, IA; Firkin, BG | 1 |
| Lanks, KW | 1 |
| Fothergill, JE; Fothergill, LA | 1 |
| Halme, J; Kivirikko, KI; Simons, K | 1 |
| Nicholson, I | 1 |
| Ermol'eva, ZV; Evseenko, LK; Iulikova, EP; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA; Silaev, AB | 1 |
| Bowman, RL; Ito, Y; Pisano, JJ; Tanimura, T | 1 |
| Grimble, RF; Whitehead, RG | 1 |
| Beale, D; Squires, M | 1 |
| Neuhoff, V; Weise, M | 1 |
| Nobel, PS; Wang, CT | 1 |
| Rathnam, P; Saxena, BB | 1 |
| Christensen, HN; Thomas, EL | 1 |
| Scougall, RK; Taylor, TG; Waring, JJ | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Boublík, M; Bradbury, EM; Crane-Robinson, C | 1 |
| Bowersox, OC; Hearn, HJ; Nagle, SC; Tribble, HR | 1 |
| Orlov, VM; Shcherbukhin, VV; Spivak, VA; Varshavsky, JM | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Pickrell, JA; Shafer, J | 1 |
| Miyatake, A; Wada, H; Watanabe, T | 1 |
| Bernini, LF; de Jong, WW; Meera Khan, P | 1 |
| Dryden, LP; Hartman, AM | 1 |
| Kloss, G; Schwarz, E | 1 |
| Bubenshchikova, SN; Katrukha, GS; Kharchenko, LI; Silaev, AB; Trufonova, ZhP | 1 |
| Greenfield, LJ; Hamilton, RD | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Bartelt, DC; DiCarlo, JJ; Greene, LJ; Sussman, AJ | 1 |
| Ellis, S; McDonald, JK; Reilly, TJ; Zeitman, BB | 1 |
| Catanzaro, OL; Hanson, RW; Lindsay, RH | 1 |
| Pikkarainen, J | 1 |
| Kristiansen, T; Porath, J | 1 |
| Chibata, I; Horie, S; Kato, J; Kisumi, M; Komatsubara, S | 1 |
| Brown, HH | 1 |
| Manahan, J; Mandl, I | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Bairos, MA; Bairos, VA | 1 |
| Harman, RE; Patterson, JL; VandenHeuvel, WJ | 1 |
| Indada, Y; Matsushima, A; Nomoto, M; Sakurai, K; Shibata, K | 1 |
| Howard, PN; Sutton, HE; Wang, AC | 1 |
| Monsigny, M; Montreuil, J; Spik, G | 1 |
| Baker, H; Cox, D; Frank, O; Hutner, SH | 1 |
| Hertel, W; Rohrlich, M | 1 |
| McConnell, WB | 1 |
| Hass, LF; Sine, HE | 1 |
| Schoonhoven, LM | 1 |
| Broad, A; Gillespie, JM | 1 |
| Landau, RL; Lugibihl, K | 1 |
| Li, CH; Papkoff, H; Samy, TS | 1 |
| Hosken, R; Sleigh, R; Smith, MB; Thompson, EO | 1 |
| Womack, M | 1 |
| Downing, SJ; Hahn, TJ; Phang, JM | 1 |
| Klein, PD; Szczepanik, PA | 1 |
| Menden, E; Vangala, RR | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Baxter, JW; Manning, M; Sawyer, WH; Wuu, TC | 1 |
| Anderson, HL; Linkswiler, H | 1 |
| Daniels, VG; Newey, H; Smyth, DH | 1 |
| Eagle, H; Levy, M; Washington, CL | 1 |
| Beljanski, M | 1 |
| Ikehara, M; Ohtsuka, E | 1 |
| Dennis, ES; Goodchild, CG | 1 |
| Money, WL; Sonenberg, M | 1 |
| Cooney, JJ; Thierry, OC | 1 |
| Gaffar, A; Sagers, RD; Terry, DR | 1 |
| Huang, JM; Wang, IS; Wang, KT | 1 |
| Christian, JH; Waltho, JA | 1 |
| Fujita, T; Hoshino, O; Ikekawa, N; Orimo, H; Watanuki, R; Yoshikawa, M | 1 |
| Gurley, LR; Kischer, CW; Shepherd, GR | 1 |
| Gutermann, H; Waldschmidt-Leitz, E | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Bourke, JB; Massey, LM; Stillings, BR | 1 |
| Adamson, LF; Ingbar, SH | 1 |
| Kathan, RH; Reichert, LE; Ryan, RJ | 1 |
| Lawrence, RC | 1 |
| Antonioli, JA; Robinson, JW; Vannotti, A | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Rigby, BJ | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Jones, HE; Park, RW | 1 |
| LaRue, TA; Spencer, JF | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Efron, ML; Mechanic, GL; Shih, VE | 1 |
| Masukawa, H; Tanaka, N; Umezawa, H | 1 |
| Oliver, IT; Yeung, D | 1 |
| Carlisle, SA; Morse, GE; Willett, NP | 1 |
| Wagh, PV; Waibel, PE | 1 |
| Jones, GE; Stewart, GJ; Tilton, RC | 1 |
| Kuroda, Y | 1 |
| Bergner, H; Betzin, B; Simon, O | 1 |
| Curriden, S; Englesberg, E; Ertsey, R; Mendiaz, E; Moffett, J | 1 |
| Claybrook, DL; Huang, AH; Yu, C | 1 |
| Aubry, A; Ghermani, N; Marraud, M | 1 |
| Englesberg, E; Ertsey, R | 1 |
| Christensen, E; Gregersen, N; Kølvraa, S | 1 |
| Caplan, AI; Hascall, VC; Kimura, JH; Nissley, SP; Rechler, MM; Stevens, RL | 1 |
| Ellory, JC; Jones, SE; Young, JD | 1 |
| Wold, F | 1 |
| Meister, A; Wellner, D | 1 |
| de Gasparo, M; Milner, RD | 1 |
| Escaig, F; Goldberg, M; Septier, D | 1 |
| Jahoor, F; Jaksic, T; Miller, RG | 1 |
| Barton, CH; Blackwell, JM; Roach, TI; White, JK | 1 |
| Kemper, B; Ramarao, M | 1 |
| Kemppainen, JA; Wilson, EM; Zhou, ZX | 1 |
| Bormann, J; Enz, R | 1 |
| Gemmecker, G; Kessler, H; Matter, H | 1 |
| Daneman, D; DeGroot, LJ; Liu, RT; Malkin, DG; Miyamoto, T; Ozata, M; Silverberg, JD; Suzuki, N; Suzuki, S; Takeda, T | 1 |
| Brugnera, E; Georgiev, O; Müller, HP; Radtke, F; Schaffner, W | 1 |
| Benson, MD; Gertz, MA; Uemichi, T | 1 |
| Goodman, HM; Lazar, G; Maniatis, T; Schaal, T | 1 |
| Goodnough, DB; Lutz, MP; Wood, PL | 1 |
| Hotta, K; Ishihara, K; Ohara, S | 1 |
| Hamaguchi, T; Imamura, K; Kono, N; Kuwajima, M; Nakajima, H; Noguchi, T; Tanaka, T; Tomita, K; Uenaka, R; Yamada, K | 1 |
| Britz-Cunningham, SH; Fletcher, WH; Shah, MM; Zuppan, CW | 1 |
| Creel, DJ; Richards, SC | 1 |
| Aggarwal, BB; Chaturvedi, MM; Darnay, BG; Singh, S | 1 |
| Chyna, B; Hayashi, Y; Refetoff, S; Sarne, D; Weiss, RE; Wing, JR | 1 |
| Ahrens, F; Mosenthin, R; Sauer, WC | 1 |
| Chuang, DT; Cox, RP; Kochi, H; Wynn, RM | 1 |
| Bertilsson, L; Ingelman-Sundberg, M; Johansson, I; Oscarson, M; Sjöqvist, F; Yue, QY | 1 |
| Iinuma, H; Naganawa, H; Shimanaka, K; Takahashi, Y; Takeuchi, T | 1 |
| Kotler, Y; Padan, E; Pinner, E; Schuldiner, S | 1 |
| Chevaillier, P | 1 |
| Brooks, DP; DePalma, D | 1 |
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| Jung, JH; Kim, YS; Lee, SM; Seo, JA | 1 |
| Eckelmann, D; Kusari, S; Spiteller, M | 1 |
| Akiba, M; Iwata, T; Kusumoto, M; Tamamura, Y; Watanabe-Yanai, A | 1 |
| Aghaabdollahian, S; Ahangari Cohan, R; Asadi Karam, MR; Davami, F; Latif Dizaji, S; Moazzami, R; Norouzian, D; Torkashvand, F; Vaseghi, G | 1 |
| Pietrangelo, A; Ridgway, ND | 1 |
| Catrina, SB; Chatzidionysiou, K; Ekberg, NR; Eliasson, S; Falhammar, H; Gu, HF; Li, YW; Zheng, X | 1 |
| Basile, W; Bassot, C; Elofsson, A; Salvatore, M | 1 |
| Garip, B; Kayir, H | 1 |
| Cha, S; Jang, KL; Jeong, H | 1 |
| Berg, MD; Brandl, CJ; Brown, GW; Loll-Krippleber, R; Yang, P; Zhu, Y | 1 |
| Adachi, K; Akita, M; Ambe, D; Morioka, K; Morita, T; Nishikawa, Y; Shigenobu, Y | 1 |
| Cohan, RA; Karami, E; Khodabakhsh, F; Khosravy, MS; Mehdizadeh, A; Salimian, M; Vafabakhsh, A | 1 |
| Abidi, A; Beriou, G; Dilek, N; Gueno, L; Lancien, M; Louvet, C; Merieau, E; Michielin, O; Nguyen, TH; Poschmann, J; Salle, S; Solomon, P; Vanhove, B; Vuillefroy de Silly, R | 1 |
| Castro, A; Dasso, M; Gasmi-Seabrook, G; Gavet, O; Joly, N; Levinson, NM; Lorca, T; Mader, P; Maisonneuve, P; Orlicky, S; Pintard, L; Poteau, M; Regmi, SG; Sicheri, F; Tavernier, N; Thomas, Y; Van Hove, L; Velez-Aguilera, G; Vigneron, S | 1 |
| Cho, K; Choi, SH; Kim, ES; Yoo, HY | 1 |
| Poonia, BK; Sharma, AB; Sidhu, A | 1 |
| Berg, MD; Brandl, CJ; Charles, B; Isaacson, JR; Jagiello, J; Moehring, AJ; Villén, J | 1 |
| Furusho, A; Hamase, K; Ishii, C; Kamarulzaman, A; Kamaruzzaman, SB; Lee, CS; Leong, KH; Mita, M; Rajasuriar, R; Shaharudin, S; Yap, SH; Zulhaimi, NS | 1 |
| Chen, Y; Dong, Z; Fan, X; Li, L; Li, Y; Sun, Y; Wang, W | 1 |
| Dahlmann, A; Diakov, A; Korbmacher, C; Nesterov, V | 1 |
| Bolgi, O; Dobbelstein, M; Donzelli, L; Geiss-Friedlander, R; Gorrell, MD; Grade, M; Huber, R; Kari, V; Killisch, M; Lenz, C; Pilla, E; Riemer, J; Ross, B; Silva-Garcia, M; Spitzner, M; Stark, N; Urlaub, H; Weiss, K | 1 |
| Juárez-López, D; Schcolnik-Cabrera, A | 1 |
| Blin, K; Charusanti, P; Genilloud, O; Gotfredsen, CH; Gren, T; Jørgensen, TS; Klitgaard, AK; Larsen, TO; Mohite, OS; Mourched, AS; Nielsen, JB; Oves-Costales, D; Tanner, D; Weber, T | 1 |
| Ates, O; Toker, EB; Yesilbag, K | 1 |
| Gao, Y; Li, L; Li, Y; Xiu, M | 1 |
| Bertini, S; Bononi, G; Caligiuri, I; Ceni, C; Di Stefano, M; Galati, S; Granchi, C; Macchia, M; Ortore, G; Poli, G; Rizzolio, F; Tuccinardi, T | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| Abadie, C; Alusse, A; Arlot-Bonnemains, Y; Chesnel, F; Couturier, A; Delalande, O; Gardie, B; Jullion, E; Le Goff, X; Lenglet, M | 1 |
| Baysal, İ; Chankvetadze, B; Gumustas, M; Kale, NB; Kır, S; Nemutlu, E; Öztepe, T; Reçber, T; Yabanoğlu-Çiftçi, S | 1 |
| Hoppins, S; Sloat, SR | 1 |
| Gafane-Matemane, L; Jacobs, A; Kruger, R; Louw, R; Mbongwa, H; Mels, C; Mokwatsi, G; Pieters, M; Schutte, AE; Strauss-Kruger, M; van Zyl, T | 1 |
| Kaczmarek, J; Kańczurzewska, M; Lalak-Kańczugowska, J; Piasecka, A; Sawikowska, A; Waśkiewicz, A; Witaszak, N | 1 |
| Binder, U; Friedrich, L; Kikuchi, Y; Matsuda, Y; Skerra, A | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Guo, Z; Hu, K; Lin, Z; Lv, P; Pan, H; Wu, T; Xue, Y; Zhang, Y | 1 |
| Hashemi, M; Moieni, A; Sabet, MS | 1 |
| Ahmad, A; Ahmad, R; Bastola, DK; Becker, DF; Dhawan, P; Kumar, B; Kumar, V; Lama Tamang, R; Patel, SM; Singh, AB; Thapa, I | 1 |
| Arai, H; Imaizumi, A; Jinzu, H; Kinoshita, K; Nishita, Y; Otsuka, R; Shimokata, H; Suzuki, K; Takada, M; Tange, C | 1 |
29 review(s) available for proline and serine
| Article | Year |
|---|---|
The role of sodium ion transport in Escherichia coli energetics.
Topics: Biological Transport, Active; Carrier Proteins; Energy Metabolism; Escherichia coli; Glutamates; Hydrogen-Ion Concentration; Melibiose; Membrane Potentials; Potassium; Proline; Serine; Sodium; Sodium-Hydrogen Exchangers; Threonine | 1991 |
Regulation of enzyme levels by proteolysis: the role of pest regions.
Topics: Amino Acid Sequence; Enzymes; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1988 |
Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles.
Topics: Benzenesulfonates; Biological Transport, Active; Carbon Radioisotopes; Cell Membrane; Cytochromes; Dinitrophenols; Escherichia coli; Kinetics; Lactose; Lysine; Mercury; NAD; Organoids; Organometallic Compounds; Oxygen Consumption; Potassium; Proline; Rubidium; Serine; Succinates; Tyrosine; Valinomycin | 1974 |
The structure and function of gastric mucus.
Topics: Animals; Chromatography, Gel; Gastric Mucins; Gels; Humans; Methods; Molecular Weight; Mucoproteins; Proline; Protein Conformation; Serine; Solutions; Swine; Threonine; Viscosity | 1972 |
A review of biochemical studies on the genetically distinct collagens of the skeletal system.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Bone and Bones; Cartilage, Articular; Collagen; Glutamates; Homoserine; Hydroxyproline; Leucine; Peptides; Phenylalanine; Proline; Rats; Serine; Threonine; Valine | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
[Chemical cleavage of peptide bonds].
Topics: Amino Acids; Chemical Phenomena; Chemistry; Histidine; Methionine; Peptides; Proline; Serine; Threonine; Tryptophan; Tyrosine | 1968 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
Function of amino acid side chains.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acids; Animals; Arginine; Bacteria; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Crystallography; Digestive System; Enzyme Activation; Enzymes; Fatty Acid Synthases; Glucose; Glucosyltransferases; Lysine; Muscles; Pancreas; Peptide Hydrolases; Phosphoglucomutase; Proline; Protein Binding; Protein Conformation; Rabbits; Serine; Structure-Activity Relationship; Trypsin; Trypsinogen | 1971 |
Amino acid nutrition of the chick--essentiality of proline and glycine biosynthesis.
Topics: Amination; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dealkylation; Dietary Proteins; Glycine; Glyoxylates; Growth; Liver; Male; Nutritional Requirements; Proline; Rats; Sarcosine; Serine; Species Specificity; Time Factors | 1971 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
A survey of inborn errors of amino acid metabolism and transport in man.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Branched-Chain; Biological Transport; Cystinosis; Female; Glutathione; Glycine; Homocystinuria; Humans; Hydroxyproline; Infant; Infant, Newborn; Lysine; Maple Syrup Urine Disease; Phenylalanine; Proline; Serine; Tyrosine; Urea; Valine | 1981 |
Pest sequences in nuclear proteins.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Nuclear Proteins; Proline; Serine; Threonine | 1993 |
PEST sequences and regulation by proteolysis.
Topics: Amino Acid Sequence; Glutamic Acid; Hydrolysis; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1996 |
Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence?
Topics: Adolescent; Amino Acid Motifs; Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line, Transformed; Cell Transformation, Viral; Epithelial Cells; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; Point Mutation; Proline; Protein Conformation; Protein Processing, Post-Translational; Sequence Deletion; Serine; Signal Transduction; src Homology Domains; Threonine; Tumor Virus Infections; Tyrosine; Viral Matrix Proteins; Virus Latency | 2000 |
Non-equilibrium proteins.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Glutamic Acid; Humans; Macromolecular Substances; Models, Molecular; Models, Theoretical; Nitric Oxide; Prions; Proline; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Proteins; Rats; Serine; Structure-Activity Relationship; Threonine | 2001 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cysteine; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Palmitic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Epoprostenol; Serine | 2007 |
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins.
Topics: Animals; Asparagine; Glycine; Humans; Ligands; Oligopeptides; Proline; Protein Conformation; Proteins; Serine; Tandem Repeat Sequences; Threonine | 2008 |
The clinical spectrum of the m.10191T>C mutation in complex I-deficient Leigh syndrome.
Topics: Adult; Brain; Child, Preschool; Electron Transport Complex I; Female; Humans; Infant; Infant, Newborn; Leigh Disease; Magnetic Resonance Imaging; Male; Point Mutation; Proline; Serine | 2012 |
SULT2B1: unique properties and characteristics of a hydroxysteroid sulfotransferase family.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Cholesterol; Cytosol; Humans; Isoenzymes; Molecular Docking Simulation; Molecular Sequence Data; Proline; Protein Binding; Sequence Alignment; Serine; Species Specificity; Sulfotransferases | 2013 |
New chemistries for chemoselective peptide ligations and the total synthesis of proteins.
Topics: Alkynes; Amino Acid Sequence; Azides; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Proteins; Serine; Threonine | 2014 |
Nonessential amino acid metabolism in breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine | 2016 |
Amino acid synthesis deficiencies.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Asparagine; Brain Diseases; Central Nervous System; Fetal Growth Retardation; Glutamine; High-Throughput Nucleotide Sequencing; Humans; Ichthyosis; Limb Deformities, Congenital; Metabolic Diseases; Mice; Microcephaly; Proline; Serine | 2017 |
PASylation as a Powerful Technology for Improving the Pharmacokinetic Properties of Biopharmaceuticals.
Topics: Alanine; Animals; Biological Products; Biopharmaceutics; Humans; Polyethylene Glycols; Proline; Radiopharmaceuticals; Serine; Treatment Outcome | 2018 |
Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer.
Topics: Amino Acids; Arginine; Carbohydrates; Glutamine; Humans; Leucine; Lipids; Male; Proline; Prostatic Neoplasms; Sarcosine; Serine; TOR Serine-Threonine Kinases | 2022 |
An update regarding the role of WNK kinases in cancer.
Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine | 2022 |
4 trial(s) available for proline and serine
| Article | Year |
|---|---|
[The significance of nonessential amino acids for the human nitrogen metabolism during parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Citrulline; Cystine; Diet; Female; Glycine; Humans; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Taurine; Tyrosine | 1968 |
Resistance to thyroid hormone in subjects from two unrelated families is associated with a point mutation in the thyroid hormone receptor beta gene resulting in the replacement of the normal proline 453 with serine.
Topics: Adult; Base Sequence; DNA; Genotype; Humans; Male; Molecular Sequence Data; Pedigree; Phenotype; Point Mutation; Proline; Receptors, Thyroid Hormone; Serine; Thyroid Function Tests; Thyroid Hormone Resistance Syndrome; Thyrotropin; Triiodothyronine | 1994 |
HIF1A P582S gene association with endurance training responses in young women.
Topics: Age Factors; Amino Acid Substitution; Exercise Test; Female; Genetic Association Studies; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Physical Education and Training; Physical Endurance; Polymorphism, Single Nucleotide; Proline; Serine; Sex Factors; Young Adult | 2011 |
Gene expression profiling indicates an increased capacity for proline, serine, and ATP synthesis and mitochondrial mass by the liver of steers grazing high vs. low endophyte-infected tall fescue.
Topics: Adenosine Triphosphate; Animal Feed; Animals; Cattle; Cattle Diseases; Endophytes; Ergot Alkaloids; Festuca; Gene Expression Profiling; Gene Expression Regulation; Male; Mitochondria, Liver; Proline; Seasons; Serine | 2015 |
835 other study(ies) available for proline and serine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Basic and neutral amino acid transport in Aspergillus nidulans.
Topics: Amino Acids; Arginine; Aspergillus nidulans; Azides; Binding, Competitive; Biological Transport, Active; Cycloheximide; Fungal Proteins; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Membrane Transport Proteins; Methionine; Mutation; Ornithine; Phenylalanine; Proline; Serine | 1976 |
13C nuclear magnetic resonance study of the cis-trans isomerism in X-Pro-Pro tripeptides.
Topics: Arginine; Carbon Isotopes; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oligopeptides; Proline; Protons; Serine; Stereoisomerism | 1978 |
The effects of sodium arsenate on the free amino acid levels in erythrocytes and plasma in rats.
Topics: Amino Acids; Aminobutyrates; Animals; Arsenates; Arsenic; Aspartic Acid; Betaine; Circadian Rhythm; Erythrocytes; Female; Glutamine; Glycine; Hydroxyproline; Isoleucine; Leucine; Male; Ornithine; Proline; Rats; Serine; Sex Factors; Starvation; Taurine; Valine | 1979 |
A simple and practical method for isolation of an early plasmin degradation product of human fibrinogen.
Topics: Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Glycine; Humans; Immunodiffusion; Methods; Molecular Weight; Proline; Serine; Threonine | 1977 |
Five steps in the conversion of a large precursor RNA into bacteriophage proline and serine transfer RNAs.
Topics: 4-Nitrophenylphosphatase; Base Sequence; Binding Sites; Coliphages; Escherichia coli; Mutation; Nucleic Acid Conformation; Oligoribonucleotides; Phosphoric Diester Hydrolases; Proline; Ribonucleases; RNA, Transfer; Serine | 1975 |
Amino acid composition of experimental salivary pellicles.
Topics: Amino Acids; Blood Group Antigens; Chemical Fractionation; Dental Deposits; Dental Pellicle; Dialysis; Glutamates; Glycine; Hemagglutination Inhibition Tests; Hemagglutination, Viral; Humans; Parotid Gland; Proline; Saliva; Salivary Proteins and Peptides; Serine; Solubility; Submandibular Gland | 1977 |
Modification of human parotid saliva proteins by oral streptococcus sanguis.
Topics: Electrophoresis, Polyacrylamide Gel; Humans; Parotid Gland; Peptide Hydrolases; Proline; Protease Inhibitors; Salivary Proteins and Peptides; Serine; Streptococcus sanguis; Sulfhydryl Compounds; Time Factors | 1979 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
[Mutation of bacteriophage T4 restoring phage supressor psul+ activity in bacterial strain Escherichia coli BN].
Topics: Base Sequence; Coliphages; Escherichia coli; Mutation; Proline; Recombination, Genetic; RNA, Transfer; RNA, Viral; Serine; Suppression, Genetic | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein.
Topics: Adult; Aged; Amino Acids; Circadian Rhythm; Dietary Proteins; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Methionine; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Blood; Cells, Cultured; Culture Media; DNA; Glycine; Kinetics; Proline; Serine | 1977 |
Regulation of plasma choline by base exchange.
Topics: 1-Propanol; Animals; Choline; Ethanolamines; Male; Proline; Propanols; Rabbits; Serine | 1977 |
Thin layer chromatographic analyses of amino acids in Echinostoma revolutum (Trematoda) adults.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Chromatography, Thin Layer; Echinostoma; Isoleucine; Leucine; Methionine; Proline; Serine; Tyrosine; Valine | 1977 |
Arangement of transfer-RNA -genes in yeast.
Topics: DNA; Genes; Methionine; Molecular Weight; Nucleic Acid Hybridization; Nucleotides; Proline; RNA, Transfer; Saccharomyces cerevisiae; Serine | 1976 |
[Amino acid pattern in endemic (Balkan-)nephropathy (author's transl)].
Topics: Adolescent; Adult; Alanine; Amino Acids; Bulgaria; Child; Citrulline; Cystine; Disease Reservoirs; Female; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Nephritis, Interstitial; Ornithine; Phenylalanine; Proline; Romania; Serine; Yugoslavia | 1976 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
Variations in the concentrations of blood plasma free amino acids in suckled and fasted neonatal pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Cystine; Fasting; Glycine; Leucine; Lysine; Proline; Serine; Swine; Threonine; Tyrosine | 1977 |
Rotational isomerism of N-acetylamino acid methylamides having serine, tyrosine, histidine, and proline residues as revealed by Raman spectroscopy.
Topics: Histidine; Isomerism; Optical Rotation; Peptides; Proline; Protein Conformation; Serine; Spectrum Analysis, Raman; Tyrosine | 1977 |
Plasma amino acids in children and adolescents on hemodialysis.
Topics: Adolescent; Amino Acids; Child; Child Nutritional Physiological Phenomena; Citrulline; Diet; Female; Glycine; Growth; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methylhistidines; Nutritional Physiological Phenomena; Proline; Renal Dialysis; Serine; Tyrosine; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Positive selection of general amino acid permease mutants in Saccharomyces cerevisiae.
Topics: Amino Acids; Ammonium Sulfate; Biological Transport, Active; Carbon Radioisotopes; Diploidy; Genetic Complementation Test; Histidine; Membrane Transport Proteins; Mutation; Proline; Saccharomyces cerevisiae; Serine; Stereoisomerism; Tyrosine | 1975 |
Three steps in conversion of large precursor RNA into serine and proline transfer RNAs.
Topics: Base Sequence; Coliphages; Crosses, Genetic; DNA Viruses; Escherichia coli; Nucleic Acid Conformation; Oligonucleotides; Proline; Recombination, Genetic; Ribonucleases; RNA, Transfer; RNA, Viral; Serine | 1975 |
Transport properties of merodiploids covering the dagA locus in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Cell Membrane; Diploidy; Escherichia coli; Genes; Glycerol; Glycine; Kinetics; Leucine; Mutation; Proline; Serine; Stereoisomerism | 1975 |
A mutant of escherichia coli defective in removing 3' terminal nucleotides from some transfer RNA precursor molecules.
Topics: Base Sequence; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Mutation; Nucleic Acid Precursors; Proline; Ribonucleases; Ribonucleotides; RNA, Transfer; RNA, Viral; Serine | 1975 |
A novel function of Escherichia coli transfer RNA nucleotidyltransferase. Biosynthesis of the C-C-A sequence in a phage T4 transfer RNA precursor.
Topics: Adenine Nucleotides; Base Sequence; Coliphages; Cytosine Nucleotides; Escherichia coli; Proline; RNA Nucleotidyltransferases; RNA, Transfer; RNA, Viral; Serine | 1975 |
The requirements of the brain for some amino acids.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Brain; Carbon Radioisotopes; Glycine; Kinetics; Proline; Rats; Serine; Sulfur Radioisotopes; Time Factors | 1975 |
Chemical and physical characteristics of a phosphoprotein from human parotid saliva.
Topics: Amino Acids, Dicarboxylic; Carbohydrates; Glycine; Hexosamines; Humans; Isoelectric Focusing; Magnetic Resonance Spectroscopy; Models, Structural; Molecular Weight; Parotid Gland; Peptide Chain Termination, Translational; Phosphates; Phosphoproteins; Proline; Protein Conformation; Saliva; Serine | 1975 |
Sequential polypeptides. Part X. The synthesis of some sequential polypeptide collagen models with functional side-chains.
Topics: Amino Acid Sequence; Collagen; Glutamine; Glycine; Lysine; Peptides; Proline; Serine; Tyrosine | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Nutrition of Vitreoscilla stercoraria.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Glutamates; Glutamine; Proline; Serine; Thiotrichaceae | 1975 |
Studies on trypsin inhibitors. Part I. Synthesis of protected peptides related to sequence 1-10 of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Alanine; Animals; Arginine; Cysteine; Glutamine; Peptides; Proline; Serine; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1976 |
Biosynthesis of amino acids from 3-(14C)-pyruvate in the fiddler crab Uca pugilator.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brachyura; Glutamates; Glutamine; Proline; Protein Biosynthesis; Pyruvates; Serine; Time Factors | 1976 |
A serine to proline substitution (S1255P) in the second nucleotide binding fold of the cystic fibrosis gene.
Topics: Adenosine Triphosphate; Base Sequence; Binding Sites; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Gene Frequency; Humans; Infant, Newborn; Male; Membrane Proteins; Point Mutation; Polymerase Chain Reaction; Proline; Serine | 1992 |
Amino acid binding by the class I aminoacyl-tRNA synthetases: role for a conserved proline in the signature sequence.
Topics: Amino Acid Sequence; Cloning, Molecular; Consensus Sequence; Escherichia coli; Kinetics; Methionine; Methionine-tRNA Ligase; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Polymerase Chain Reaction; Proline; Sequence Homology, Amino Acid; Serine | 1992 |
Characterization of the stabilizing effect of point mutations of pyruvate oxidase from Lactobacillus plantarum: protection of the native state by modulating coenzyme binding and subunit interaction.
Topics: Alanine; Amino Acid Sequence; Asparagine; Enzyme Stability; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Pyruvate Oxidase; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Thiamine Pyrophosphate; Urea; Valine | 1992 |
A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation killer of prune) affects stability but not catalytic efficiency of the enzyme.
Topics: Amino Acids; Animals; Catalysis; Chromatography, Gel; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Enzyme Stability; Insect Hormones; Isoelectric Focusing; Kinetics; Mutation; Nucleoside-Diphosphate Kinase; Proline; Protein Denaturation; Serine; Spectrometry, Fluorescence; Temperature; Urea | 1992 |
Adsorption from salivary fractions at solid/liquid and air/liquid interfaces.
Topics: Adsorption; Chromatography; Histidine; Humans; Proline; Saliva; Salivary Proteins and Peptides; Serine; Silicon Dioxide; Surface Properties; Surface Tension; Threonine; Water | 1992 |
Escherichia coli is able to grow with negligible sodium ion extrusion activity at alkaline pH.
Topics: Alkalies; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Cell Division; Escherichia coli; Genes, Bacterial; Hydrogen-Ion Concentration; Ions; Mutation; Proline; Serine; Sodium; Sodium-Hydrogen Exchangers | 1992 |
Amino acid transport systems in the human hepatoma cell line Hep G2.
Topics: Alanine; Amino Acids; Biological Transport; Carcinoma, Hepatocellular; Humans; Kinetics; Lithium; Liver Neoplasms; Proline; Serine; Sodium; Tumor Cells, Cultured | 1992 |
The presence of free D-alanine, D-proline and D-serine in mice.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Kidney; Mice; Mice, Mutant Strains; Proline; Serine; Stereoisomerism | 1992 |
Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; Glutamates; Glutamic Acid; Hematopoietic Stem Cells; Histocompatibility Antigens; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leukocyte Common Antigens; Male; Mice; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Organ Specificity; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; RNA; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Substrate Specificity; Threonine | 1992 |
A serine, threonine and proline-rich region near the carboxyl-terminus of a rat intestinal mucin peptide.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; DNA; Intestinal Mucosa; Molecular Sequence Data; Mucins; Proline; Rats; Repetitive Sequences, Nucleic Acid; Restriction Mapping; RNA; RNA, Messenger; Sequence Homology, Nucleic Acid; Serine; Threonine | 1992 |
A serine-->proline change in the Alzheimer's disease-associated epitope Tau 2 results in altered secondary structure, but phosphorylation overcomes the conformational gap.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cattle; Circular Dichroism; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Molecular Sequence Data; Peptides; Phosphorylation; Proline; Protein Conformation; Serine; tau Proteins | 1992 |
Pro-453 to Ser mutation in CYP21 is associated with nonclassic steroid 21-hydroxylase deficiency.
Topics: Adrenal Hyperplasia, Congenital; Base Sequence; DNA; Female; Humans; Molecular Sequence Data; Point Mutation; Proline; Serine | 1992 |
The presence of free D-serine, D-alanine and D-proline in human plasma.
Topics: Adult; Aged; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Male; Middle Aged; Proline; Reference Values; Serine; Stereoisomerism | 1992 |
Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Base Sequence; Chromatography, Affinity; Female; Fibrinogen; Genetic Variation; Humans; Macromolecular Substances; Male; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Pedigree; Platelet Activation; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Proline; RNA, Messenger; Serine; Thrombasthenia | 1992 |
Determination of D- and L-amino acids in mouse kidney by high-performance liquid chromatography.
Topics: Alanine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Kidney; Mice; Proline; Serine; Stereoisomerism | 1992 |
A novel missense mutation in the antithrombin III gene (Ser349----Pro) causing recurrent venous thrombosis.
Topics: Adolescent; Adult; Antithrombin III; Antithrombin III Deficiency; DNA Mutational Analysis; Female; Humans; Male; Mutation; Pedigree; Polymerase Chain Reaction; Proline; Serine; Thrombophlebitis | 1992 |
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Binding Sites; Brain; Cattle; Cloning, Molecular; Humans; Microtubules; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Plasmids; Proline; Protein Kinases; Serine; Swine; tau Proteins | 1992 |
Peptidyldiazomethanes. A novel mechanism of interaction with prolyl endopeptidase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Diazomethane; Endopeptidases; Kidney; Kinetics; Molecular Sequence Data; Muscles; Peptides; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Protein Denaturation; Serine; Serine Endopeptidases; Swine | 1992 |
Identification of a prenylation site in delta virus large antigen.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antigens, Viral; Cell Line; Cysteine; Hepatitis delta Antigens; Hepatitis Delta Virus; Mevalonic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; Serine; Transfection; Virus Replication | 1992 |
Purification and microsequencing of the intra-acrosomal protein SP-10. Evidence that SP-10 heterogeneity results from endoproteolytic processes.
Topics: Acrosome; Amino Acid Sequence; Antibodies, Monoclonal; Antigens; Blotting, Western; Chromatography, Affinity; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glutamates; Glycine; Gonadal Steroid Hormones; Humans; Male; Membrane Proteins; Molecular Sequence Data; Polymorphism, Genetic; Proline; Serine | 1992 |
The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs.
Topics: Alzheimer Disease; Amino Acid Sequence; Brain; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Microtubules; Molecular Sequence Data; Mutation; Phosphorylation; Proline; Protein Binding; Protein Kinases; Serine; tau Proteins; Threonine | 1992 |
Amino acid composition of acquired enamel pellicle collected in vivo after 2 hours and after 24 hours.
Topics: Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Diet; Fasting; Glutamates; Glutamic Acid; Glycine; Humans; Proline; Serine; Time Factors | 1991 |
Structure of the SPXX motif.
Topics: Amino Acid Sequence; Binding Sites; DNA-Binding Proteins; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Proline; Protein Conformation; Serine; Structure-Activity Relationship | 1991 |
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Cell Line; Cloning, Molecular; Complement System Proteins; DNA, Neoplasm; Exons; Genomic Library; HeLa Cells; Humans; Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Oligonucleotide Probes; Phenotype; Poly A; Polymerase Chain Reaction; Proline; RNA; RNA Splicing; RNA, Messenger; Serine; Threonine; Transfection | 1991 |
Missense mutation serine106----proline causes 17 alpha-hydroxylase deficiency.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Alleles; Base Sequence; Blotting, Northern; Blotting, Southern; Chromatography, Thin Layer; DNA; Electrophoresis, Polyacrylamide Gel; Female; Homozygote; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Pregnenolone; Progesterone; Proline; RNA; Serine; Steroid 17-alpha-Hydroxylase | 1991 |
Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins.
Topics: Aged; Alanine; Antithrombin III; Base Sequence; Binding Sites; Exons; Heparin; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Serpins; Threonine; Thrombophlebitis; United Kingdom | 1991 |
Glycosylation sites identified by detection of glycosylated amino acids released from Edman degradation: the identification of Xaa-Pro-Xaa-Xaa as a motif for Thr-O-glycosylation.
Topics: Amino Acid Sequence; Animals; Cell Line; Glycopeptides; Glycosylation; Humans; Molecular Sequence Data; Peptide Fragments; Proline; Proteins; Rats; Serine; Threonine; Transfection | 1991 |
Analysis of neutral amino acid transport systems in the small intestine: a study of brush border membrane vesicles.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Culture Media; Cysteine; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Microvilli; Proline; Serine | 1991 |
Glomerulopressin production by isolated rat liver after amino acid infusion.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Analysis of Variance; Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Glucuronates; Infusions, Intravenous; Liver; Male; Muscle Tonus; Muscle, Smooth; Proline; Rats; Rats, Inbred Strains; Serine | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
The Staphylococcus aureus chromosomal gene plaC, identified by mutations amplifying plasmid pT181, encodes a sigma factor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Mutation; Plasmids; Proline; Promoter Regions, Genetic; Restriction Mapping; Serine; Sigma Factor; Staphylococcus aureus | 1991 |
Influenza virus ts61S hemagglutinin is significantly defective in polypeptide folding and intracellular transport at the permissive temperature.
Topics: Animals; Antibody Specificity; Cell Line; Exocytosis; Fluorescent Antibody Technique; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Influenza A virus; Kinetics; Mutation; Proline; Protein Conformation; Protein Processing, Post-Translational; Serine; Temperature; Viral Envelope Proteins | 1991 |
Evaluating the effects of a single amino acid substitution on both the native and denatured states of a protein.
Topics: Amino Acid Sequence; Calorimetry; Escherichia coli; Glutathione; Kinetics; Mathematics; Mutagenesis, Site-Directed; Oxidation-Reduction; Proline; Protein Denaturation; Proteins; Serine; Thioredoxins | 1991 |
Pest sequences present in the subunits of phosphorylase kinase.
Topics: Amino Acid Sequence; Animals; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Muscles; Phosphorylase Kinase; Proline; Rabbits; Serine; Threonine | 1990 |
Serine-proline replacement at residue 127 of NADH-cytochrome b5 reductase causes hereditary methemoglobinemia, generalized type.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Blood Platelets; Cytochrome Reductases; Cytochrome-B(5) Reductase; Erythrocytes; Female; Genomic Library; Homozygote; Humans; Lymphocytes; Male; Methemoglobin; Methemoglobinemia; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Pedigree; Proline; Reference Values; Restriction Mapping; Serine | 1990 |
Structural, functional, and subunit assembly properties of hemoglobin Attleboro [alpha 138 (H21) Ser----Pro], a variant possessing a site maturation at a critical C-terminal residue.
Topics: Amino Acid Sequence; Child, Preschool; Female; Hemoglobins, Abnormal; Humans; Ligands; Macromolecular Substances; Molecular Sequence Data; Molecular Structure; Mutation; Oxygen; Oxyhemoglobins; Postural Balance; Proline; Protein Binding; Serine | 1990 |
Effects of amino acid isomers on canine renal hemodynamics.
Topics: Alanine; Amino Acids; Animals; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Male; Proline; Renal Circulation; Serine; Stereoisomerism | 1990 |
Amino acid substitutions Phe66----Leu and Ser126----Pro abolish cortisol and aldosterone synthesis by bovine cytochrome P450(11)beta.
Topics: Adrenal Cortex; Aldosterone; Animals; Base Sequence; Cattle; Cell Line; Cloning, Molecular; Codon; Desoxycorticosterone; DNA; Hydrocortisone; Leucine; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phenylalanine; Plasmids; Polymerase Chain Reaction; Proline; RNA, Messenger; Serine; Steroid 11-beta-Hydroxylase; Transfection | 1990 |
Change of serine309 into proline causes temperature sensitivity of the nuclear NAM1/MTF2 gene product for yeast mitochondria.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Fungal Proteins; Genes, Fungal; Mitochondrial Proteins; Molecular Sequence Data; Mutation; Nuclear Proteins; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Temperature; Transcription Factors | 1990 |
A radioautographic comparison of in vivo 3H-proline and 3H-serine incorporation in the pulpal dentine of rat molars: variations according to the different zones.
Topics: Animals; Autoradiography; Dental Pulp; Dentin; Male; Molar; Odontoblasts; Proline; Rats; Rats, Inbred Strains; Serine; Tritium | 1990 |
Heerlen polymorphism of protein S, an immunologic polymorphism due to dimorphism of residue 460.
Topics: Adult; Alleles; Amino Acid Sequence; Amino Acids; Antibodies, Monoclonal; Base Sequence; Blood Donors; Cytosine; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Glycoproteins; Glycosylation; Humans; Male; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Polymorphism, Genetic; Proline; Protein S; Serine; Thymine | 1990 |
A case of Fabry's disease in a patient with no alpha-galactosidase A activity caused by a single amino acid substitution of Pro-40 by Ser.
Topics: alpha-Galactosidase; Base Sequence; Blotting, Northern; Cells, Cultured; DNA; Fabry Disease; Galactosidases; Humans; Lysosomes; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Skin | 1990 |
Nature of the renal hemodynamic action of amino acids in dogs.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Anesthesia, General; Animals; Dogs; Female; Glomerular Filtration Rate; Liver; Male; Proline; Renal Circulation; Serine; Splanchnic Circulation | 1989 |
SPXX, a frequent sequence motif in gene regulatory proteins.
Topics: Amino Acid Sequence; Amino Acids; Animals; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histones; Models, Molecular; Molecular Sequence Data; Proline; Proteins; Serine; Threonine; Transcription Factors | 1989 |
Characteristics of acidic, basic and neutral amino acid transport in the perfused rat hindlimb.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Female; Glutamates; Glycine; Hindlimb; Insulin; Kinetics; Lysine; Methylhistidines; Proline; Rats; Rats, Inbred Strains; Sarcolemma; Serine; Sodium | 1989 |
Ribosomal protein S12 as a site for streptomycin resistance in Nicotiana chloroplasts.
Topics: Base Sequence; Chloroplasts; Cloning, Molecular; Codon; Drug Resistance; Exons; Mutation; Nicotiana; Plant Proteins; Plants, Toxic; Proline; Ribosomal Proteins; Serine; Streptomycin | 1989 |
Single amino acid changes that alter the DNA sequence specificity of the DNA-[N6-adenine] methyltransferase (Dam) of bacteriophage T4.
Topics: Amino Acid Sequence; Base Sequence; Codon; DNA, Viral; Escherichia coli; Genes, Viral; Kinetics; Molecular Sequence Data; Mutation; Plasmids; Proline; Serine; Site-Specific DNA-Methyltransferase (Adenine-Specific); T-Phages; Viral Structural Proteins | 1989 |
Changes in the concentrations of hydroxyproline, glycine and serine in the plasma of haemodialysis patients undergoing erythropoietin therapy.
Topics: Adult; Aged; Anemia; Erythropoietin; Female; Follow-Up Studies; Glycine; Hemoglobins; Humans; Hydroxyproline; Male; Middle Aged; Parathyroid Hormone; Proline; Recombinant Proteins; Renal Dialysis; Serine | 1989 |
beta-Amyloid precursor is a PEST protein.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.
Topics: Amino Acid Sequence; Caseins; Glutamates; Glutamic Acid; Half-Life; HeLa Cells; Humans; Proline; Proteins; Serine; Threonine | 1986 |
Mutagenesis of the alpha subunit of the F1Fo-ATPase from Escherichia coli. Mutations at Glu-196, Pro-190, and Ser-199.
Topics: Amino Acid Sequence; Escherichia coli; Glutamates; Glutamic Acid; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutation; Plasmids; Proline; Protein Conformation; Proton-Translocating ATPases; Serine; Spectrometry, Fluorescence | 1988 |
Alteration in cation specificity of the melibiose transport carrier of Escherichia coli due to replacement of proline 122 with serine.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; Escherichia coli; Lithium; Membrane Transport Proteins; Mutation; Proline; Protons; Serine; Symporters | 1985 |
Substitution of a serine residue for proline-87 reduces catalytic activity and increases susceptibility to proteolysis of Escherichia coli adenylate kinase.
Topics: Adenine Nucleotides; Adenylate Kinase; Amino Acid Sequence; Circular Dichroism; Escherichia coli; Hot Temperature; Mutation; Phosphotransferases; Proline; Protein Conformation; Serine; Trypsin | 1986 |
Echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.
Topics: Absorption; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Cycloleucine; Diffusion; Echinococcus; Hydrogen-Ion Concentration; Leucine; Methionine; Proline; Serine; Valine | 1986 |
[Ser7]neurotensin: isolation from guinea pig intestine.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Cattle; Chromatography, High Pressure Liquid; Guinea Pigs; Intestine, Small; Neurotensin; Proline; Radioimmunoassay; Serine | 1986 |
Root-analogue versus crown-analogue dentin: a radioautographic and ultrastructural investigation of the mouse incisor.
Topics: Animals; Autoradiography; Dentin; Female; Incisor; Mice; Mice, Inbred Strains; Microscopy, Electron; Proline; Serine; Tooth Root; Tritium | 1986 |
L-proline uptake in human fibroblasts: evidence for a high-affinity system in addition to system A.
Topics: Aminoisobutyric Acids; Biological Transport; Cells, Cultured; Fibroblasts; Glycine; Humans; Kinetics; Proline; Serine | 1987 |
Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.
Topics: Alanine; Amino Acids; Biological Transport, Active; Fibroblasts; Humans; Kinetics; Lysosomes; Mathematics; Osmolar Concentration; Proline; Serine; Sodium Chloride; Threonine | 1987 |
Extracellular accumulation of proline, serine and trehalose in the haemolymph of osmoconforming brackish-water mosquitoes.
Topics: Amino Acids; Animals; Culex; Disaccharides; Electrolytes; Extracellular Space; Hemolymph; Larva; Osmolar Concentration; Proline; Serine; Trehalose | 1987 |
Feedback control of selected biosynthetic activities of chondrocytes in culture.
Topics: Animals; Cartilage; Cell Count; Chickens; Chondrosarcoma; Collagen; Comb and Wattles; Feedback; Humans; Hyaluronic Acid; Proline; Protein Biosynthesis; Proteoglycans; Rats; Serine; Sulfates; Thymidine; Tumor Cells, Cultured; Umbilical Cord | 1987 |
C1 binding by murine IgM. The effect of a Pro-to-Ser exchange at residue 436 of the mu-chain.
Topics: Complement Activating Enzymes; Complement Activation; Complement C1; Complement C1q; Complement C4; Complement C4b; Immunoglobulin M; Immunoglobulin mu-Chains; Osmolar Concentration; Proline; Serine | 1988 |
Phosphoprotein synthesis and secretion by odontoblasts in rat incisors as revealed by electron microscopic radioautography.
Topics: Animals; Autoradiography; Incisor; Male; Microscopy, Electron; Odontoblasts; Phosphoproteins; Proline; Rats; Rats, Inbred Strains; Serine | 1988 |
Structural effects of substitutions on the p21 proteins.
Topics: Amino Acid Sequence; Glycine; Humans; Lysine; Models, Molecular; Neoplasm Proteins; Proline; Protein Conformation; Proto-Oncogene Proteins p21(ras); Serine; Structure-Activity Relationship; Valine | 1985 |
Synthesis and degradation in vivo of a phosphoprotein from rat dental enamel. Identification of a phosphorylated precursor protein in the extracellular organic matrix.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Enamel Organ; Extracellular Space; Phosphoproteins; Proline; Protein Precursors; Serine | 1985 |
Hemoglobin North Chicago (beta 36 [C2] proline----serine): a new high affinity hemoglobin.
Topics: Amino Acid Sequence; Blood Protein Electrophoresis; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Electrophoresis, Cellulose Acetate; Electrophoresis, Polyacrylamide Gel; Globins; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Male; Middle Aged; Peptide Fragments; Polycythemia; Proline; Serine | 1985 |
Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibody Formation; Antigens; Aspartic Acid; Binding Sites; Carbon Isotopes; Clostridium; Complement Fixation Tests; Complement System Proteins; Dialysis; Electrophoresis; Epitopes; Ferredoxins; Formates; Glutamates; Glutamine; Haptens; Immune Sera; Immunoglobulin G; Isoleucine; Lysine; Oxidation-Reduction; Peptides; Proline; Rabbits; Serine; Tyrosine; Valine | 1971 |
Methanolysis of the pyrrolidone ring of amino-terminal pyroglutamic acid in model peptides.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Benzyl Compounds; Butanols; Chromatography, Gas; Crystallization; Esters; Hydrolysis; Isoleucine; Leucine; Lysine; Methanol; Peptides; Proline; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Serine; Staining and Labeling | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
The position of various cleavages of rabbit immunoglobulin G.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bromine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; gamma-Globulins; Glutamates; Leucine; Lysine; Pepsin A; Proline; Rabbits; Serine; Sulfhydryl Compounds; Threonine; Trypsin | 1968 |
RNA metabolism in Streptomyces antibioticus; effect of 5-fluorouracil on the appearance of phenoxazinone synthetase.
Topics: Amino Acids; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chromatography; Dactinomycin; Fluorouracil; ortho-Aminobenzoates; Oxazines; Oxidoreductases; Proline; RNA, Bacterial; RNA, Transfer; Serine; Streptomyces; Time Factors; Tritium; Uridine | 1970 |
Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.
Topics: Alanine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Histidine; Methionine; Methyltransferases; Mutation; Prodigiosin; Proline; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine; Serratia marcescens; Stereoisomerism; Tetrahydrofolates | 1973 |
D-amino acids in the cell pool of bacteria.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Bacillus subtilis; Bacteria; Chromatography, Thin Layer; Clostridium; Culture Media; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Lactobacillus; Leucine; Proline; Serine; Spectrophotometry; Staphylococcus; Stereoisomerism; Temperature; Tyrosine | 1974 |
Comparative biochemistry of keratosulfates.
Topics: Animals; Aspartic Acid; Biochemical Phenomena; Biochemistry; Cartilage; Cattle; Cornea; Electrophoresis; Fishes; Glutamates; Glycosaminoglycans; Hexosamines; In Vitro Techniques; Physiology, Comparative; Poultry; Proline; Serine; Sharks; Threonine | 1965 |
Structure of human skeletal keratosulfate. The linkage region.
Topics: Alkalies; Amino Acids; Carbohydrates; Cartilage; Chromatography, Gel; Chromatography, Paper; Fucose; Glutamine; Glycosaminoglycans; Hexosamines; Humans; Keratins; Molecular Weight; Proline; Serine; Sulfates; Tritium | 1967 |
Sulfated glycopeptides and glycosaminoglycan peptides isolated from intestinal mucosae of rabbit.
Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Colon; Electrophoresis; Fucose; Galactose; Glycoproteins; Glycosaminoglycans; Hexosamines; Hexoses; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Light; Methods; Neuraminic Acids; Organ Specificity; Peptides; Proline; Rabbits; Rotation; Serine; Spectrophotometry; Sulfates; Threonine; Ultracentrifugation; Uronic Acids | 1969 |
Human cardiac myosin. Biochemical and structural characterization.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Chromatography, Gel; Dogs; Heart Valve Prosthesis; Heart Ventricles; Humans; Molecular Weight; Muscle Proteins; Papillary Muscles; Proline; Rheumatic Heart Disease; Serine; Sulfhydryl Compounds; Threonine; Ultracentrifugation; Valine; Viscosity | 1970 |
Ribosomal proteins. XXII. Studies on the altered protein S5 from a spectinomycin-resistant mutant of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acids; Antibiotics, Antineoplastic; Bacterial Proteins; Chromatography, DEAE-Cellulose; Chromatography, Paper; Drug Resistance, Microbial; Escherichia coli; Mutation; Peptides; Proline; Ribosomes; Serine; Spectinomycin; Structure-Activity Relationship; Trypsin | 1972 |
A mutant of Escherichia coli defective in the coupling of metabolic energy to active transport.
Topics: Adenosine Triphosphatases; Amino Acids; Amino Sugars; Arabinose; Biological Transport, Active; Carbon Radioisotopes; Chromosome Mapping; Coliphages; Energy Metabolism; Escherichia coli; Genotype; Glucose; Lactates; Mutation; Proline; Serine; Succinates; Transduction, Genetic | 1974 |
The natural occurrence of a uracil-5-peptide and its metabolic relationship to guanosine-5'-monophosphate.
Topics: Arginine; Chromatography, Paper; Glycine; Guanine Nucleotides; In Vitro Techniques; Peptide Biosynthesis; Perchlorates; Plants, Edible; Proline; Seeds; Serine; Spectrophotometry; Uracil | 1966 |
[Use of amino acids and pathogenic and non-pathogenic E. coli with increased resistance to a number of antibiotics in experiments in vitro and in the process of treatment of patients with colienteritis].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Child; Chloramphenicol; Chlortetracycline; Colistin; Drug Resistance, Microbial; Enteritis; Escherichia coli; Escherichia coli Infections; Glutamates; Glycine; Humans; In Vitro Techniques; Oxytetracycline; Proline; Serine; Streptomycin; Viomycin | 1967 |
Amino acid uptake in isolated chick embryo heart cells.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Chick Embryo; Glycine; Heart; Histidine; In Vitro Techniques; Insulin; Leucine; Methionine; Microbial Collagenase; Myocardium; Oxygen Consumption; Proline; Protein Biosynthesis; Serine; Threonine | 1969 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
The extracellular nuclease activity of Micrococcus sodonensis. IV. Physical studies, characterization as a glycoprotein and involvement with the cell wall.
Topics: Amino Acids; Animals; Cell Wall; Chromatography, Paper; Galactose; Glucosamine; Glucose; Glycine; Glycoproteins; Immunodiffusion; Micrococcus; Molecular Weight; Phosphoric Monoester Hydrolases; Proline; Rabbits; Rhamnose; Ribonucleases; Serine; Threonine; Time Factors; Tryptophan; Ultracentrifugation | 1970 |
Lysyl-protocollagen hydroxylase deficiency in fibroblasts from siblings with hydroxylysine-deficient collagen.
Topics: Adolescent; Adult; Amino Acids; Cells, Cultured; Child; Collagen; Consanguinity; Ehlers-Danlos Syndrome; Female; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hydroxylysine; L-Lactate Dehydrogenase; Lysine; Male; Metabolism, Inborn Errors; Methyltransferases; Mixed Function Oxygenases; Procollagen-Proline Dioxygenase; Proline; Protein Precursors; Serine; Skin; Time Factors | 1972 |
The isolation and the structure of new glycopeptide from blood group substances.
Topics: Acetamides; Alanine; Asparagine; Blood Group Antigens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Galactosamine; Glucosamine; Glycopeptides; Humans; Optical Rotation; Oxidation-Reduction; Periodic Acid; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Chymotrypsin; Cytochrome c Group; Electrophoresis; Genes; Heme; Hydrolysis; Isoleucine; Mutation; Peptides; Proline; RNA, Messenger; Saccharomyces cerevisiae; Serine; Threonine; Ultraviolet Rays | 1974 |
Transfer RNA genes in mitochondrial DNA of grande (wild-type) yeast.
Topics: Amino Acyl-tRNA Synthetases; Aspartic Acid; Chromatography; Cytoplasm; Cytosol; DNA, Mitochondrial; Escherichia coli; Genes; Glutamates; Histidine; Hot Temperature; Kinetics; Lysine; Mitochondria; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Proline; RNA, Transfer; Saccharomyces cerevisiae; Serine; Silicon Dioxide; Tritium; Tyrosine | 1974 |
[On the mechanism of action of 1-nitroso-3-nitro-1-methylguanidine in the induction of mutation. I. Effect of 1-nitroso-3-nitro-1-methylguanidine on the template activity of polyncleotides in cell-free protein synthesis].
Topics: Adenine Nucleotides; Amino Acids; Bacterial Proteins; Cell-Free System; Cytosine Nucleotides; Escherichia coli; Guanidines; Guanine Nucleotides; Leucine; Lysine; Molecular Biology; Mutagens; Mutation; Nitroso Compounds; Phenylalanine; Polynucleotides; Proline; Ribosomes; RNA, Bacterial; RNA, Transfer; Serine; Templates, Genetic; Tritium; Uracil Nucleotides | 1967 |
[On the synthesis of serine peptides].
Topics: Amino Acid Sequence; Azides; Esters; Glycine; Peptides; Proline; Serine | 1969 |
[Synthetic polypeptides of the sequences (glycine-L-proline-L-serine)n and (glycine-L-serine-L-proline)].
Topics: Amino Acid Sequence; Antimetabolites; Chromatography, Gel; Cyclohexanes; Glycine; Imides; Molecular Weight; Peptides; Proline; Pyrrolidinones; Serine | 1969 |
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.
Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays | 1971 |
Mutant strains of Escherichia coli K12 that use D-amino acids.
Topics: Amino Acids; Arginine; Chromosome Mapping; Coliphages; D-Amino-Acid Oxidase; Escherichia coli; Genetic Linkage; Genotype; Histidine; Isoleucine; Isomerism; Leucine; Lysine; Mutation; Phenylalanine; Proline; Serine; Threonine; Transduction, Genetic; Tryptophan; Tyrosine; Valine | 1971 |
Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Atropine; Chromatography, Ion Exchange; Esters; Guinea Pigs; Histamine H1 Antagonists; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proline; Rabbits; Rats; Receptors, Drug; Serine; Skin; Structure-Activity Relationship; Tissue Extracts | 1972 |
Preparation of some 2-phenylisopropyl-oxycarbonyl amino acids. Evaluation of their properties with particular reference to application in solid phase peptide synthesis.
Topics: Amino Acids; Bradykinin; Carbonates; Chromatography, Thin Layer; Dimethyl Sulfoxide; Glycine; Guanidines; Methods; Optical Rotation; Peptides; Phenylalanine; Proline; Serine; Time Factors | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Amino acid transport in human placental slices.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Paper; Extracellular Space; Female; Glutamates; Glycine; Humans; In Vitro Techniques; Kidney; Leucine; Lysine; Placenta; Pregnancy; Proline; Rats; Serine; Time Factors | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Study of serum amino acids in Egyptian lead workers.
Topics: Adult; Alanine; Amino Acids; Colorimetry; Egypt; Glutamates; Glycine; Histidine; Humans; Lead Poisoning; Leucine; Lysine; Male; Middle Aged; Proline; Serine; Tyrosine; Valine | 1974 |
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo.
Topics: Alanine; Animals; Aspartic Acid; Chemical Fractionation; Chick Embryo; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Proline; Ribonucleases; RNA, Transfer; Serine; Tyrosine; Valine | 1974 |
Mode of action on proteins of acid carboxypeptidase from Aspergillus saitoi.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Aspergillus; Carboxypeptidases; Cattle; Egg White; Hydrogen-Ion Concentration; Kinetics; Methods; Muramidase; Phenylalanine; Proline; Proteins; Ribonucleases; Serine; Surface-Active Agents; Time Factors; Valine | 1974 |
Characterization of human colonic mucoprotein antigen.
Topics: Amino Acids; Animals; Antigens; Carbohydrates; Carcinoembryonic Antigen; Colon; Fucose; Galactose; Glucosamine; Glutamates; Glycine; Humans; Immune Sera; Immunoelectrophoresis; Molecular Weight; Mucoproteins; Neuraminic Acids; Proline; Rabbits; Serine; Threonine | 1974 |
Amino acid and glucose uptake by the isolated perfused guinea-pig mammary gland.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Caseins; Female; Glucose; Glutamates; Guinea Pigs; Lactation; Mammary Glands, Animal; Organ Size; Perfusion; Pregnancy; Proline; Serine; Time Factors | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Stimulation of chondromucoprotein synthesis in chondrocytes by extracellular chondromucoprotein.
Topics: Acetates; Animals; Carbon Isotopes; Cartilage; Cells, Cultured; Chromatography, Paper; Cytarabine; Dactinomycin; Glucosamine; Mucoproteins; Proline; Protein Biosynthesis; Puromycin; Rats; Serine; Sulfates; Sulfur Isotopes; Trypsin | 1972 |
Identification of tRNA precursor molecules made by phage T4.
Topics: Base Sequence; Chromatography, Thin Layer; Coliphages; Electrophoresis, Polyacrylamide Gel; Genes; Hydrolysis; Lysogeny; Mutation; Oligonucleotides; Phosphorus Radioisotopes; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Transcription, Genetic | 1973 |
Transfer RNA biosynthesis: the nucleotide sequence of a precursor to serine and proline transfer RNAs.
Topics: Base Sequence; Coliphages; Lysogeny; Polynucleotides; Proline; RNA, Transfer; RNA, Viral; Serine | 1974 |
Chemotaxis toward amino acids in Escherichia coli.
Topics: Amino Acids; Aspartic Acid; Bacteriological Techniques; Chemotaxis; Culture Media; Escherichia coli; Genetics, Microbial; Mutation; Oxygen Consumption; Proline; Serine; Threonine | 1972 |
Carboxyl terminal amino acid sequence of guinea pig 1 G.
Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Cyanogen Bromide; Guinea Pigs; Immunization; Immunoglobulin Fc Fragments; Immunoglobulin G; Isoleucine; Pepsin A; Peptides; Proline; Serine; Trypsin | 1972 |
Structure of a hypothalamic peptide possessing gonadotropin-releasing activity.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Carbon Isotopes; Glutamates; Glycine; Gonadotropins; Histidine; Hypothalamus; Leucine; Mass Spectrometry; Peptide Chain Termination, Translational; Pituitary Hormone-Releasing Hormones; Proline; Serine; Swine; Tryptophan; Tyrosine | 1972 |
Synthesis and biological activities of analogs of luteinizing hormone-releasing hormone (LH-RH) substituted in position 1 or 2.
Topics: Animals; Castration; Female; Glutamates; Glycine; Leucine; Luteinizing Hormone; Ovary; Peptide Chain Elongation, Translational; Phenylalanine; Pituitary Hormone-Releasing Hormones; Proline; Rats; Serine; Structure-Activity Relationship | 1973 |
Detection of inosine-containing transfer ribonucleic acid species by affinity chromatography on columns of anti-inosine antibodies.
Topics: Alkylation; Animals; Antibodies; Arginine; Carbon Radioisotopes; Chromatography, Affinity; Cyanides; Escherichia coli; Evaluation Studies as Topic; Guanosine; Inosine; Isoleucine; Methionine; Methods; Proline; Rabbits; RNA, Bacterial; RNA, Transfer; Serine; Structure-Activity Relationship; Threonine; Transfer RNA Aminoacylation; Tritium; Valine | 1973 |
Studies on L-serine deaminase in Escherichia coli K-12.
Topics: Amino Acids; Cell-Free System; Deamination; Drug Stability; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; L-Serine Dehydratase; Mutation; Nitrogen; Proline; Pyruvates; Serine; Stereoisomerism; Succinates; Threonine; Toluene | 1974 |
The production of an antibiotic substance by Mycobacterium album subsp hyalinum Krasilnikov, 1941.
Topics: Anti-Bacterial Agents; Bacteria; Culture Media; Escherichia coli; Mycobacterium; Proline; Serine; Soil Microbiology; Temperature; Time Factors; Tryptophan; Valine | 1972 |
Studies on T4-tRNA biosynthesis: accumulation of precursor tRNA molecules in a temperature sensitive mutant of Escherichia coli.
Topics: Base Sequence; Coliphages; Densitometry; Drug Stability; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Leucine; Mutation; Phosphorus Radioisotopes; Proline; Ribonucleases; Ribonucleotides; RNA, Transfer; RNA, Viral; Serine; Temperature; Time Factors; Transcription, Genetic; Virus Replication | 1974 |
Proline metabolism in Leishmania donovani promastigotes.
Topics: Alanine; Arginine; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Glucose; Glutamates; Leishmania; Malate Dehydrogenase; Malates; Methionine; Methods; Oxygen Consumption; Proline; Pyruvates; Serine | 1972 |
Synthesis of sequence peptide polymers related to collagen.
Topics: Alanine; Amino Acid Sequence; Collagen; Glycine; Hydroxyproline; Methods; Peptides; Polymers; Proline; Serine | 1972 |
Sequence of limiting amino acids in gelatin for the growing chick.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Gelatin; Glycine; Histidine; Isoleucine; Lysine; Male; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Valine | 1972 |
Genetic analysis of free plasma amino acids in pure strains of mature chickens.
Topics: Amino Acids; Animals; Autoanalysis; Breeding; Chickens; Female; Genotype; Isoleucine; Male; Molecular Biology; Phenotype; Proline; Serine; Statistics as Topic; Threonine; Valine | 1972 |
Permeability of human buccal mucosa to an amino acid analogue, the antibiotic D-cycloserine.
Topics: Alanine; Cheek; Cycloserine; Humans; Hydrogen-Ion Concentration; Methionine; Mouth Mucosa; Proline; Serine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Studies on protamines. XVI. The complete amino acid sequence of clupeine YII.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography; Fishes; Male; Proline; Protamines; Serine; Spermatozoa; Threonine; Valine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Radioautographic visualization of the deposition of a phosphoprotein at the mineralization front in the dentin of the rat incisor.
Topics: Animals; Autoradiography; Collagen; Dentin; Incisor; Methods; Microscopy; Microscopy, Electron; Odontoblasts; Phosphates; Phosphoproteins; Phosphorus Isotopes; Proline; Rats; Serine; Time Factors; Tritium | 1973 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
[Animal experiment studies on uptake of amino acids applied to the nasal mucosa].
Topics: Adsorption; Amino Acids; Aminobutyrates; Animals; Arginine; Biological Transport, Active; Carbon Isotopes; Glutamates; Glycine; Nasal Mucosa; Proline; Rabbits; Serine | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Developmental transitions in uptake of amino acids by synaptosomal fractions isolated from rat cerebral cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Carbon Isotopes; Cerebral Cortex; Kinetics; Proline; Rats; Serine; Sodium; Stimulation, Chemical; Synaptosomes; Threonine; Valine | 1973 |
Role of riboflavin and certain amino acids in the excystment of Schizopyrenus russelli.
Topics: Amino Acids; Amoeba; Animals; Chloromercuribenzoates; Culture Media; Emetine; Glutamates; Isoleucine; Proline; Riboflavin; Serine; Tryptophan | 1973 |
Hybrid formation between collagen and synthetic polypeptides.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Glycine; Hybridization, Genetic; Molecular Conformation; Molecular Weight; Optical Rotation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Rabbits; Serine; Skin; Temperature; Tropomyosin | 1973 |
Amino acid and peptide requirement of Fusiformis necrophorus.
Topics: Amino Acids; Anaerobiosis; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Culture Media; Fusobacterium; Glucose; Peptides; Proline; Serine; Stereoisomerism | 1973 |
Effect of cortisol treatment on free amino acid levels in rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Glycine; Hydrocortisone; Liver; Male; Muscle Proteins; Muscles; Proline; Rats; Serine | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Cattle; Collagen; Energy Metabolism; Glucose; Glutamates; Glutathione; In Vitro Techniques; Lactates; Lens, Crystalline; Leucine; Lipid Metabolism; Lysine; Oxidation-Reduction; Proline; Serine; Taurine; Tryptophan; Tyrosine | 1973 |
A lysine-rich protein from spermatozoa of the mollusc Mytilus edulis.
Topics: Alanine; Amino Acids; Animals; Arginine; Bivalvia; Chromatin; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Histones; Hydrogen-Ion Concentration; Lysine; Male; Molecular Weight; Peptide Fragments; Proline; Protamines; Proteins; Serine; Spermatozoa; Thiocyanates; Trypsin | 1974 |
Synthesis and catalytic properties of the heptapeptide L-seryl-L-prolyl-L-cysteinyl-L-steryl-alpha-L-glutamyl-L-threonyl-L-tyrosine.
Topics: Acetates; Carboxypeptidases; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dicyclohexylcarbodiimide; Esters; Glutamates; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrophenols; Oligopeptides; Optical Rotation; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Threonine; Tyrosine | 1974 |
An acetylated N-terminus of adenovirus type 2 hexon protein.
Topics: Acetylation; Adenoviridae; Alanine; Amino Acid Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Mass Spectrometry; Peptide Fragments; Proline; Serine; Threonine; Time Factors; Viral Proteins | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
[Alkaline hydrolysis and the ester linkage of some normal and modified aminoacyl-tRNA].
Topics: Alkalies; Amino Acids; Chemical Phenomena; Chemistry; Escherichia coli; Glyoxylates; Hydrogen-Ion Concentration; Phenylacetates; Phenylalanine; Proline; RNA, Bacterial; RNA, Transfer; Saccharomyces; Serine; Sulfur Isotopes; Surface-Active Agents; Temperature; Tritium | 1966 |
Mechanism of action of bottromycin in polypeptide biosynthesis.
Topics: Anti-Bacterial Agents; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chloramphenicol; Dialysis; Escherichia coli; Leucine; Peptides; Phenylalanine; Proline; Protein Binding; Puromycin; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Valine | 1968 |
An application of diagonal electrophoresis to the selective purification of serine phosphate peptides. Serine phosphate peptides from ovalbumin.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Chymotrypsin; Electrophoresis; Isoleucine; Leucine; Lysine; Ovalbumin; Pepsin A; Peptides; Proline; Serine; Trypsin | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
[Study of the inactivation of the acceptor properties of transfer ribonucleic acids by ionizing radiation].
Topics: Alkaline Phosphatase; Amino Acids; Carbon Isotopes; Chromatography; Cobalt Isotopes; Escherichia coli; Esters; Isoleucine; Leucine; Phenylalanine; Phosphates; Proline; Radiation Effects; RNA, Transfer; Saccharomyces; Serine; Solutions; Spectrophotometry; Water | 1968 |
Unavailability of cystine from trypsin inhibitors as a factor contributing to the poor nutritive value of navy beans.
Topics: Amino Acids; Animals; Aspartic Acid; Chickens; Chymotrypsin; Cystine; Diet; Feces; Glutamates; Hot Temperature; Intestinal Mucosa; Nutritional Physiological Phenomena; Organ Size; Pancreas; Pepsin A; Plant Proteins; Plants, Edible; Proline; Protein Binding; Serine; Threonine; Trypsin; Trypsin Inhibitors | 1969 |
Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2'(3')-O-aminoacyladenosines.
Topics: Acetates; Acyltransferases; Alanine; Amino Acids; Binding Sites; Carbon Isotopes; Escherichia coli; Glutamine; Glycine; Imidazoles; Leucine; Lysine; Methionine; Nucleosides; Peptides; Phenylalanine; Proline; Ribosomes; RNA, Transfer; Serine; Stereoisomerism; Valine | 1970 |
Messenger and template activities of chemically modified polynucleotides.
Topics: Adenosine Triphosphate; Alkylating Agents; Carbon Isotopes; Cell-Free System; Cytosine Nucleotides; Escherichia coli; Guanidines; Guanine Nucleotides; Hydroxylamines; Leucine; Mutation; Nitrites; Nitroso Compounds; Phenylalanine; Polynucleotides; Proline; Radiation Effects; RNA Nucleotidyltransferases; RNA, Transfer; Serine; Templates, Genetic; Ultraviolet Rays; Uracil Nucleotides | 1970 |
Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacteriological Techniques; Caseins; Culture Media; Filtration; Glutamates; Ornithine; Pigments, Biological; Prodigiosin; Proline; Protein Hydrolysates; Pyrroles; Serine; Serratia marcescens; Stereoisomerism; Temperature | 1971 |
2'-O-Methyl polynucleotides as templates for cell-free amino acid incorporation.
Topics: Adenine Nucleotides; Amino Acids; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Cytosine Nucleotides; Escherichia coli; Ethers; Genetic Code; Isoleucine; Kinetics; Leucine; Methanol; Methylation; Molecular Biology; Neomycin; Phenylalanine; Polynucleotides; Proline; Protein Biosynthesis; Ribonucleotides; RNA, Bacterial; Serine; Templates, Genetic; Tyrosine; Uracil Nucleotides | 1971 |
Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Arginine; Chemical Phenomena; Chemistry; Chymotrypsin; Endopeptidases; Follicle Stimulating Hormone; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hypothalamus; Leucine; Luteinizing Hormone; Mass Spectrometry; Methods; Naphthalenes; Peptides; Pituitary Hormone-Releasing Hormones; Proline; Serine; Sulfonic Acids; Swine; Thiocyanates; Tritium; Tryptophan; Tyrosine | 1971 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Species differences of serum amino acid beta-napthylamidases.
Topics: Alanine; Amides; Amino Acids; Aminopeptidases; Animals; Arginine; Chickens; Cyprinidae; Dipeptides; Dogs; Female; Glutamine; Glycine; Haplorhini; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Naphthalenes; Phenylalanine; Proline; Rats; Serine; Species Specificity; Valine | 1968 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
Amino acid pool formation in Pseudomonas aeruginosa.
Topics: Amides; Amino Acids; Arginine; Carbon Isotopes; Chloramphenicol; Cold Temperature; Glutamates; Glycine; Histidine; Kinetics; Membrane Transport Proteins; Nitrogen; Proline; Pseudomonas aeruginosa; Serine; Valine | 1969 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
[Glycopeptides of immunoglobulins, Microheterogeneity of the oligosaccharide chains of an immunoglobulin M from Waldenstrom's disease].
Topics: Amino Acid Sequence; Aspartic Acid; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Histidine; Humans; Immunoglobulin M; Immunoglobulins; Lysine; Mannose; Neuraminic Acids; Oligosaccharides; Papain; Peptides; Proline; Serine; Threonine; Tyrosine; Valine; Waldenstrom Macroglobulinemia | 1970 |
Isolation of a macroglycopeptide from human platelets.
Topics: Blood Platelets; Cell Membrane; Chromatography, DEAE-Cellulose; Chromatography, Gel; Diffusion; Electrophoresis, Disc; Galactose; Glucosamine; Glycopeptides; Hexosamines; Humans; Immunodiffusion; Mathematics; Molecular Weight; Mucins; Neuraminic Acids; Papain; Peptide Hydrolases; Peptides; Platelet Adhesiveness; Polysaccharides; Proline; Serine; Threonine; Trypsin; Ultracentrifugation | 1970 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Solubilization and chemical and immunochemical characterization of sparingly soluble canine gastric mucin.
Topics: Alkylation; Amino Acids; Animals; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dogs; Electrophoresis; Ethylmaleimide; Fucose; Galactose; Gastric Mucins; Gastric Mucosa; Glucosamine; Glycoproteins; Hexosamines; Immunodiffusion; Immunoelectrophoresis; Neuraminic Acids; Oxidation-Reduction; Phosphates; Proline; Rabbits; Serine; Sodium; Sodium Chloride; Sodium Hydroxide; Solubility; Sulfhydryl Reagents; Sulfites; Sulfur Isotopes; Threonine | 1971 |
Synthesis and structural studies of two collagen analogues: poly (L-prolyl-L-seryl-glycyl) and poly (L-prolyl-L-alanyl-glycyl).
Topics: Circular Dichroism; Collagen; Esters; Glycine; Models, Chemical; Molecular Weight; Peptides; Polymers; Proline; Serine; Solvents | 1972 |
Characteristics of amino acid accumulation by synaptosomal particles isolated from rat brain.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Carbon Isotopes; Leucine; Lysine; Nerve Endings; Ouabain; Potassium; Proline; Rats; Serine; Sodium; Stimulation, Chemical; Synaptic Vesicles; Synaptosomes; Threonine; Tyrosine; Valine | 1972 |
The effect of dietary lysine level, restriction of food intake and sampling time on the levels of amino acids in the blood plasma of chicks.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Eating; Glycine; Lysine; Proline; Serine; Time Factors | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Oxygen equilibrium characteristics of abnormal hemoglobins. Hirose (alpha-2-beta-2-37Ser), L Ferrara (alpha-2-47-Gly-beta-2), Broussais (alpha-2-90-Asn-beta-2), and Dhofar (alpha-2-beta-2-58Arg).
Topics: Arginine; Asparagine; Aspartic Acid; Electrophoresis, Starch Gel; Genetic Variation; Glycine; Hemoglobins, Abnormal; Heterozygote; Humans; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Mathematics; Oxygen; Partial Pressure; Polarography; Proline; Serine; Tryptophan | 1972 |
Transfer RNA changes in rat granulation tissue possibly related to collagen synthesis.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Cellulose; Chromatography, DEAE-Cellulose; Collagen; Glycine; Granulation Tissue; Leucine; Lysine; Male; Proline; Rats; RNA, Transfer; Serine; Time Factors; Tritium | 1972 |
Haemoglobin Denmark Hill 95 (G2) Pro-Ala, a variant with unusual electrophoretic and oxygen-binding properties.
Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Electrophoresis, Paper; Electrophoresis, Starch Gel; Female; Gestational Age; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Leucine; London; Molecular Biology; Mutation; Oxygen; Peptides; Pregnancy; Proline; Protein Binding; Serine | 1972 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Quantitative changes in plasma amino acids induced by oral contraceptives.
Topics: Adult; Alanine; Amino Acids; Contraceptives, Oral; Female; Glutamine; Glycine; Gonadal Steroid Hormones; Humans; Isoleucine; Leucine; Ornithine; Ovulation; Proline; Serine; Tyrosine; Valine | 1971 |
Dentin matrix collagen: evidence for a covalently linked phosphoprotein attachment.
Topics: Animals; Aspartic Acid; Cattle; Chemistry Techniques, Analytical; Chromatography; Chromatography, Gas; Collagen; Dentin; Electrophoresis, Disc; Galactose; Gels; Glucose; Hydroxyproline; Iodates; Phosphates; Proline; Serine; Solubility; Ultracentrifugation | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Kinetic analysis of insulin action on amino acid uptake by isolated chick embryo heart cells.
Topics: Amino Acids; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Chick Embryo; Fetal Heart; Glycine; Insulin; Inulin; Kinetics; Proline; Serine; Tritium | 1971 |
The amino acid-fermenting clostridia.
Topics: Amino Acids; Arginine; Caseins; Chromatography, Paper; Clostridium; Culture Media; Fermentation; Glucose; Glutamates; Glycine; Histidine; Proline; Serine; Threonine | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Application of gas-liquid radiochromatography to determination of the optical purity of carbon-14 labeled amino acids.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chlorella; Chromatography, Gas; Cold Temperature; Drug Stability; Leucine; Methods; Proline; Serine; Stereoisomerism; Time Factors; Valine | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Mouse insulins--separation and structures.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Formates; Insulin; Iodine Isotopes; Isotope Labeling; Lysine; Methionine; Mice; Oxidation-Reduction; Peptides; Proline; Serine; Trypsin | 1971 |
The characterization of hereditary abnormalities of keratin: Clouston's ectodermal dysplasia.
Topics: Ectodermal Dysplasia; Genes, Dominant; Hair; Humans; Keratosis; Nails, Malformed; Phenylalanine; Proline; Serine; Sulfur; Tyrosine; Urea; Water | 1971 |
Comparison of invariant residues in the variable and constant regions of human K, human L, and mouse K Bence-Jones proteins.
Topics: Amino Acid Sequence; Animals; Bence Jones Protein; Cysteine; Glutamates; Histidine; Humans; In Vitro Techniques; Leucine; Lysine; Mice; Phenylalanine; Proline; Serine; Tryptophan; Valine | 1967 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Transfer RNA species in normal and leukemic human lymphoblasts.
Topics: Amino Acids; Carbon Isotopes; Cell Line; Chromatography; Glutamine; Glycine; Humans; Leucine; Leukemia, Lymphoid; Ligases; Lymphocytes; Proline; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine | 1970 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
[Transport of amino acids across lymphocyte membrane in human peripheral blood].
Topics: Amino Acids; Aspartic Acid; Biological Transport, Active; Cell Membrane; Glycine; Humans; Kinetics; Leucine; Lymphocytes; Lysine; Methionine; Proline; Radioisotopes; Serine; Temperature | 1969 |
Structure studies of collocalia mucoid. I. Carbohydrate and amino acid composition.
Topics: Amino Acids; Aspartic Acid; Carbohydrates; Fucose; Galactose; Glucosamine; Glutamates; Glycoproteins; Hemagglutination Inhibition Tests; Hexosamines; Neuraminic Acids; Orthomyxoviridae; Proline; Serine; Threonine; Valine | 1969 |
Isolation of gastroferrin from human gastric juice.
Topics: Amino Acids; Autoanalysis; Chelating Agents; Chemical Precipitation; Chromatography, Gel; Dialysis; Fucose; Galactose; Gastric Juice; Glucosamine; Glycoproteins; Hexosamines; Humans; Hydroxides; Iron; Iron-Binding Proteins; Methods; Molecular Weight; Neuraminic Acids; Proline; Protein Binding; Proteins; Serine; Threonine; Ultracentrifugation | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
Evidence from amino acid analysis for a relationship in the biosynthesis of gamma- and beta-caseins.
Topics: Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Computers; Electrophoresis, Disc; Glutamates; Hexoses; Histidine; Hydrogen-Ion Concentration; Lysine; Methods; Milk; Molecular Biology; Peptides; Phosphorus; Proline; Serine; Tryptophan; Urea | 1969 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glutamates; Glycine; Growth; Male; Nutritional Requirements; Proline; Rats; Serine | 1970 |
Amino acid transport into human platelets and subsequent incorporation into protein.
Topics: Amino Acids; Biological Transport; Blood Platelets; Blood Proteins; Carbon Isotopes; Cell Membrane; Cysteine; Fibrin; Fibrinogen; Glutamates; Humans; Leucine; Lysine; Microscopy, Electron; Mitochondria; Proline; Puromycin; Serine; Thrombin; Valine | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
Thiol and disulphide contents of hen ovalbumin. C-terminal sequence and location of disulphide bond.
Topics: Animals; Carbon Isotopes; Chickens; Chloromercuribenzoates; Chromatography; Cysteine; Electrophoresis; Female; Imines; Iodoacetates; Ovalbumin; Peptides; Proline; Serine; Sulfides; Trypsin; Valine | 1970 |
Isolation and partial characterization of highly purified protocollagen proline hydroxylase.
Topics: Alcohols; Amino Acids; Animals; Aspartic Acid; Benzoates; Chick Embryo; Chromatography, Gel; Collagen; Electrophoresis, Disc; Ethylmaleimide; Glutamates; Glycine; Isoflurophate; Lysine; Mercury; Methods; Mixed Function Oxygenases; Molecular Weight; Proline; Serine; Sulfur; Ultracentrifugation | 1970 |
Prediction and explanation of chemical mutation sites.
Topics: Arginine; Asparagine; Genetic Code; Genetics, Microbial; Glycine; Leucine; Models, Chemical; Mutagens; Mutation; Nucleotides; Phenylalanine; Proline; RNA, Viral; Serine; Tobacco Mosaic Virus | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Droplet countercurrent chromatography.
Topics: Alanine; Amino Acids; Chromatography; Countercurrent Distribution; Cystine; Dinitrophenols; Fluorocarbon Polymers; Ornithine; Proline; Serine; Threonine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
C-terminal amino-acid sequence of bovine immunoglobulin light chain.
Topics: Amino Acid Sequence; Animals; Carboxypeptidases; Cattle; Chromatography, Gel; Immunoglobulin G; Immunoglobulins; Lysine; Naphthalenes; Peptides; Proline; Serine; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Isolation and physicochemical characterization of luteinizing hormone from human pituitary glands.
Topics: Amino Acids; Animals; Blood Proteins; Chorionic Gonadotropin; Chromatography, Ion Exchange; Cross Reactions; Electrophoresis, Disc; Female; Follicle Stimulating Hormone; Goats; Humans; Immune Sera; Immunoelectrophoresis; Isoelectric Focusing; Luteinizing Hormone; Male; Molecular Weight; Ovary; Pituitary Gland; Proline; Prostate; Rabbits; Rats; Serine; Sucrose; Thyrotropin; Ultracentrifugation | 1970 |
Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Canavanine; Columbidae; Erythrocytes; Guanidines; Lysine; Models, Biological; Models, Structural; Ornithine; Proline; Propionates; Rabbits; Reticulocytes; Serine; Sodium; Threonine | 1970 |
Changes in the plasma concentrations of free amino acids in relation to egg formation in the hen.
Topics: Amino Acids; Animals; Arginine; Chickens; Circadian Rhythm; Cystine; Eggs; Estrogens; Feeding Behavior; Female; Glutamates; Histidine; Lysine; Male; Ornithine; Ovum; Proline; Serine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
An investigation of the conformational changes in histones F1 and F2a1 by proton magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glycine; Histones; Magnetic Resonance Spectroscopy; Muramidase; Optical Rotatory Dispersion; Osmolar Concentration; Papain; Proline; Ribonucleases; Serine; Sodium Chloride; Threonine | 1970 |
Replication of Venezuelan equine encephalomyelitis virus in vitro. II. Viral growth response to selected nutritional additives in suspension cultures.
Topics: Animals; Arboviruses; Choline; Culture Media; Encephalomyelitis, Equine; L Cells; Mice; Proline; Serine; Virulence; Virus Cultivation; Virus Replication | 1971 |
Quantitative ultramicroanalysis of amino acids in the form of their DNS-derivatives. II. On the use of the dansylation reaction for quantitative estimation of amino acids.
Topics: Amino Acids; Chromatography, Thin Layer; Fluorescence; Glycine; Leucine; Mathematics; Methods; Microchemistry; Naphthalenes; Proline; Serine; Sulfonic Acids; Time Factors | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
Lung connective tissue measurements. I. Amino acid analysis procedures for determination of canine lung connective tissue.
Topics: Animals; Aspartic Acid; Autoanalysis; Chromatography, Ion Exchange; Collagen; Connective Tissue; Dogs; Elastin; Glutamates; Hydroxyproline; Lung; Lysine; Proline; Pulmonary Fibrosis; Radiation Injuries, Experimental; Serine; Threonine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
Haemoglobin Rampa: Alpha 95 Pro--Ser.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, DEAE-Cellulose; Chymotrypsin; Hemoglobins, Abnormal; Humans; India; Peptides; Proline; Serine; Trypsin | 1971 |
Vitamin B12 deficiency in the rat fed high protein rations.
Topics: Amino Acids; Animals; Caseins; Depression, Chemical; Dietary Proteins; Formates; Glycine; Growth; Isoleucine; Male; Malonates; Nitrogen; Proline; Propionates; Rats; Serine; Stereoisomerism; Threonine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
The utilization of free amino acids by marine sediment microbiota.
Topics: Amino Acids; Arginine; Glutamates; Lysine; Marine Biology; Proline; Serine; Tryptophan; Water | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Two trypsin inhibitors from porcine pancreatic juice.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glutamates; Glutamine; Guanidines; In Vitro Techniques; Kallikreins; Molecular Weight; Pancreatic Juice; Proline; Serine; Species Specificity; Spectrum Analysis; Swine; Threonine; Trypsin; Trypsin Inhibitors; Ultracentrifugation; Ultraviolet Rays | 1968 |
Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization.
Topics: Acid Phosphatase; Alanine; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Dipeptides; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Kidney; Kinetics; Leucine; Lithium; Lysine; Lysosomes; Methionine; Naphthalenes; Nucleosides; Pituitary Gland; Potassium; Proline; Protease Inhibitors; Puromycin; Rats; Serine; Sodium; Spleen; Thyroid Gland; Tromethamine; Tyrosine | 1968 |
Secretion of amino acids in dog parotid saliva.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Cell-Free System; Dogs; Glycine; Infusions, Parenteral; Parotid Gland; Phenylalanine; Proline; Proteins; Saliva; Salivary Glands; Serine | 1968 |
The molecular structures of vertebrate skin collagens. A comparative study.
Topics: Amino Acids; Animals; Anura; Arginine; Autoanalysis; Biological Evolution; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Chromatography; Collagen; Electrophoresis; Fishes; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Leucine; Methionine; Optical Rotatory Dispersion; Proline; Serine; Sharks; Skin; Snakes; Solubility; Temperature; Threonine; Valine | 1968 |
Studies on blood group substances. I. Purification of active material from hog gastric mucin by specific precipitation with Vicia cracca phytohemagglutinin.
Topics: Adsorption; Amino Acids; Animals; Blood Group Antigens; Chemical Precipitation; Chromatography, Gel; Dialysis; Gastric Mucins; Hemagglutination Inhibition Tests; Lectins; Proline; Serine; Swine; Threonine | 1968 |
Production of L-proline by Kurthia catenaforma.
Topics: Ammonium Chloride; Aspartic Acid; Bacteria; Culture Media; Glucose; Hydrogen-Ion Concentration; Phosphates; Potassium; Proline; Serine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Gas chromatographic behavior of trimethylsilylated phenylthiohydantoin amino acids.
Topics: Alanine; Amino Acids; Arginine; Chromatography, Gas; Glutamates; Glutamine; Hydantoins; Leucine; Methionine; Methods; Methylation; Phenylalanine; Proline; Serine; Silicon; Spectrum Analysis; Tyrosine | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Transferrin DChi: the amino acid substitution.
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Glutamates; Histidine; Humans; Lysine; Peptides; Proline; Serine; Transferrin; Trypsin; Valine | 1968 |
[Studies on glycoproteins. XXV. The C-terminal amino acids of human transferrin and lactotransferrin].
Topics: Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Glycine; Glycoproteins; Humans; Lactoglobulins; Peptides; Proline; Serine; Transferrin | 1968 |
Growth of Tetrahymena in carbohydate-free high-glutamate media.
Topics: Animals; Culture Media; Glutamates; Hydrogen-Ion Concentration; Proline; Serine; Tetrahymena | 1968 |
[Incorporation of 14C-proline into ripening wheat].
Topics: Asparagine; Carbon Isotopes; Chromatography, Thin Layer; Glycine; Peptides; Plant Proteins; Proline; Serine; Threonine; Triticum | 1968 |
Studies on wheat plants using 14C-labelled compounds. XXII. Incorporation into wheat protein.
Topics: Amino Acids; Arginine; Aspartic Acid; Carbon Dioxide; Chromatography, Ion Exchange; Citric Acid Cycle; Glutamates; Glutamine; Glutens; Glycine; Glyoxylates; Plant Proteins; Proline; Seeds; Serine; Succinates; Triticum | 1969 |
Studies on the structure and function of muscle aldolase. IV. The action of dilute alkali on primary structure and its effect on the determination of subunit molecular weight.
Topics: Aldehyde-Lyases; Alkalies; Animals; Boron Compounds; Buffers; Carboxypeptidases; Chemical Phenomena; Chemistry; Computers; Electrophoresis; Electrophoresis, Disc; Glycine; Hexosephosphates; Hydrogen-Ion Concentration; Molecular Weight; Muscles; Peptides; Proline; Rabbits; Serine; Solubility; Succinates; Temperature; Threonine; Time Factors; Ultracentrifugation | 1969 |
Amino-acid receptor in larvae of Pieris brassicae (Lepidoptera).
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Chemoreceptor Cells; Cysteine; Glutamates; Glycine; Insecta; Leucine; Methionine; Proline; Serine; Stimulation, Chemical | 1969 |
A further study on the dietary-regulated biosynthesis of high-sulphur wool proteins.
Topics: Abomasum; Animals; Aspartic Acid; Caseins; Chromatography, Ion Exchange; Cystine; Dietary Proteins; Electrophoresis; Nutritional Physiological Phenomena; Phenylalanine; Proline; Protein Biosynthesis; Serine; Sheep; Sulfur; Wool | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
The terminal amino acid residues of ovine interstitial cell-stimulating hormone and its subunits.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Chromatography, Paper; Chromatography, Thin Layer; Female; Leucine; Luteinizing Hormone; Proline; Serine; Sheep; Thiocyanates | 1969 |
Chemical characterization of a non-covalently linked peptide from plakalbumin.
Topics: Alanine; Albumins; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Hydrazines; Methods; Ovalbumin; Peptides; Proline; Serine; Urea | 1969 |
Amino acid feeding studies: effects of various nonessential nitrogen sources and of added water.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Body Weight; Diet; Glutamates; Glycine; Male; Nitrogen; Proline; Rats; Serine | 1969 |
Amino acid transport in adult diaphyseal bone: contrast with amino acid transport mechanisms in fetal membranous bone.
Topics: Age Factors; Alanine; Amides; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Bone and Bones; Carbon Isotopes; Cyanides; Depression, Chemical; Female; Fluorides; Hydroxyproline; Imines; Membranes; Methods; Pregnancy; Proline; Rats; Serine; Sodium; Sucrose; Tibia; Time Factors; Tritium | 1969 |
Local solvent structure as a factor in secondary isotope fractionation phenomena of labeled amino acids on ion-exchange columns.
Topics: Alcohols; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glutamates; Glycine; Phenylalanine; Proline; Serine; Solvents; Tritium; Tyrosine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
4-Proline analogues of neurohypophysial hormones: hypothetical intermediates in peptide evolution.
Topics: Amino Acid Sequence; Animals; Anura; Female; Glutamine; In Vitro Techniques; Lactation; Molecular Biology; Mutation; Oviducts; Pituitary Hormones, Posterior; Pregnancy; Proline; Rabbits; Rats; Serine; Urinary Bladder; Urodela; Uterus | 1969 |
Effect of source of dietary nitrogen on plasma concentration and urinary excretion of amino acids of men.
Topics: Adult; Amino Acids; Arginine; Caseins; Citrates; Diet; Fasting; Glutamates; Glycine; Histidine; Humans; Male; Nitrogen; Proline; Quaternary Ammonium Compounds; Serine; Taurine; Threonine; Time Factors | 1969 |
Stereochemical specificity of neutral amino acid transfer systems in rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cysteine; Hydroxyproline; Ileum; Intestine, Small; Jejunum; Leucine; Methionine; Pipecolic Acids; Proline; Rats; Sarcosine; Serine; Stereoisomerism | 1969 |
End product control of amino acid synthesis by cultured human cells.
Topics: Alanine; Arginine; Culture Techniques; Enzyme Repression; Glucose; Glutamine; Glycine; Humans; Methionine; Ornithine; Proline; Serine | 1965 |
[RNA isolated from turnip yellow mosaic virus; acceptor of amino acids in the presence of bacterial enzymes].
Topics: Alanine; Alcaligenes; Amino Acids; Arginine; In Vitro Techniques; Isoleucine; Leucine; Nucleotides; Phenylalanine; Plant Viruses; Proline; RNA, Viral; Serine; Ultracentrifugation; Valine | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Inhibition of bovine growth hormone activity by acetyl proteins.
Topics: Acetates; Albumins; Animals; Antimetabolites; Body Weight; Caseins; Cattle; Growth Hormone; Hypophysectomy; Proline; Rats; Serine; Serum Albumin, Bovine; Threonine; Thyrotropin | 1966 |
A defined medium for growth and pigment synthesis of Micrococcus roseus.
Topics: Adenine; Amines; Arginine; Culture Media; Fructose; Glutamates; Glycine; Isoleucine; Leucine; Lutein; Methionine; Mevalonic Acid; Micrococcus; Pigments, Biological; Proline; Salts; Serine; Spectrophotometry | 1966 |
Amino acid compostion of walls from single and filamentous cells of Clostridium acidiurici.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Cell Wall; Chromatography; Clostridium; Glutamates; Glycine; In Vitro Techniques; Isomerases; Leucine; Lysine; Methionine; Oxidoreductases; Phenylalanine; Proline; Serine; Valine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
The metabolism of triglycerides by spores of Penicillium roqueforti.
Topics: Alanine; Azides; Chloramphenicol; Dinitrophenols; Enzymes; Esterases; Glycerides; Isoflurophate; Ketones; Oxygen Consumption; Penicillium; Phosphates; Proline; Serine; Spores; Triglycerides | 1967 |
Amino-acid transport by various leucocyte preparations: a comparative survey.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Cyanides; Dinitrophenols; Fluorides; Glycine; Guinea Pigs; In Vitro Techniques; Iodoacetates; Leucine; Leukocytes; Lymph Nodes; Lysine; Methionine; Proline; Serine; Spleen | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Correlation between serine and thermal stability of collagen.
Topics: Animals; Annelida; Ascaris; Cattle; Collagen; Fishes; Hot Temperature; Humans; Hydroxyproline; Proline; Rats; Serine; Snails; Threonine; Tyrosine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
The influence of medium composition on the growth and swarming of Proteus.
Topics: Alanine; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Proline; Proteus; Serine | 1967 |
The utilization of D-amino acids by yeasts.
Topics: Alanine; Amino Acids; Candida; Cryptococcus; Glutamates; Proline; Saccharomyces; Serine; Sewage; Soil Microbiology; Water Microbiology; Yeasts | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Structural basis of kanamycin for miscoding activity.
Topics: Adenine Nucleotides; Amines; Amino Acids; Amino Sugars; Arginine; Chemical Phenomena; Chemistry; Cytosine Nucleotides; DNA; Genetic Code; Isoleucine; Kanamycin; Leucine; Lysine; Phenylalanine; Polynucleotides; Proline; Serine; Threonine; Uracil Nucleotides; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
Metabolism of L-arabinose and D-xylose by chicks.
Topics: Alkaline Phosphatase; Animals; Arabinose; Carbohydrates; Carbon Isotopes; Chickens; Chlorides; Cholesterol; Diet; Dietary Carbohydrates; Glucose; Hematocrit; Lipid Metabolism; Liver; Male; Organ Size; Pentoses; Potassium; Proline; Serine; Xylose | 1967 |
Marine Thiobacilli. II. Culture and ultrastructure.
Topics: Agar; Amino Acids; Cell Membrane; Cell Nucleus; Cell Wall; Culture Media; Cytoplasm; Cytoplasmic Granules; Flagella; Hydrogen-Ion Concentration; Marine Biology; Microscopy, Electron; Nitrates; Oxygen; Phosphates; Proline; Salts; Serine; Sulfides; Sulfites; Sulfur; Thiobacillus; Thiosulfates; Yeast, Dried | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
[Investigation of the feed value of straw].
Topics: Animal Feed; Animals; Arginine; Body Weight; Dietary Fiber; Digestion; Edible Grain; Glutamates; Isoleucine; Proline; Serine; Swine | 1980 |
Alanine-resistant mutants of Chinese hamster ovary cells, CHO-K1, producing increases in velocity of proline transport through the A, ASC, and P systems.
Topics: Alanine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Glutamine; Kinetics; Mutation; Ovary; Proline; Serine | 1983 |
Transport of glycine, serine, and proline into spinach leaf mitochondria.
Topics: Biological Transport, Active; Glycine; Kinetics; Mitochondria; Oxygen Consumption; Plants; Proline; Serine | 1983 |
Backbone side chain interactions in peptides. I. Crystal structures of model dipeptides with the Pro-Ser sequence.
Topics: Dipeptides; Hydrogen Bonding; Models, Molecular; Proline; Protein Conformation; Serine; Structure-Activity Relationship; X-Ray Diffraction | 1984 |
Recessive 2-(methylamino)-isobutyrate (MeAIB)-resistant mutant of Chinese hamster ovary cells (CHO-K1) with increased transport through ASC system.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cell Line; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Female; Genes, Recessive; Kinetics; Mutation; Ovary; Proline; Serine | 1984 |
In vivo studies on the metabolic derangement in a patient with D-glyceric acidaemia and hyperglycinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Dehydrogenases; Child, Preschool; Diet; Fructose; Glyceric Acids; Glycine; Humans; Male; Proline; Propionates; Riboflavin; Serine | 1984 |
Effects of insulin and multiplication-stimulating activity on proteoglycan biosynthesis in chondrocytes from the Swarm rat chondrosarcoma.
Topics: Animals; Cartilage; Cell Line; Chondrosarcoma; DNA; DNA, Neoplasm; Glucosamine; Insulin; Insulin-Like Growth Factor II; Kinetics; Liver; Neoplasms, Experimental; Peptides; Proline; Proteoglycans; Rats; Serine | 1981 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
Effect of non-essential amino acids on fetal rat pancreatic growth and insulin secretion in vitro.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Glycine; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Proline; Rats; Rats, Inbred Strains; Serine | 1981 |
The effects of vinblastine on the cell structure and activity in the rat incisor enamel organ during the secretory stage in vivo as shown by radioautography using 3H-proline, 3H-serine and 3H-fucose.
Topics: Ameloblasts; Animals; Autoradiography; Enamel Organ; Fucose; Organoids; Proline; Rats; Rats, Inbred Strains; Serine; Tooth Germ; Tritium; Vinblastine | 1982 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
NH2-terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Carrier Proteins; Cation Transport Proteins; Cloning, Molecular; DNA; Iron-Binding Proteins; Macrophages; Membrane Proteins; Molecular Sequence Data; Proline; Proto-Oncogene Proteins pp60(c-src); Sequence Homology; Serine | 1994 |
Substitution at residue 473 confers progesterone 21-hydroxylase activity to cytochrome P450 2C2.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Stability; Glycine; Kidney; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Proline; Sequence Homology, Amino Acid; Serine; Steroid 21-Hydroxylase; Structure-Activity Relationship; Valine | 1995 |
Identification of three proline-directed phosphorylation sites in the human androgen receptor.
Topics: Alanine; Animals; Binding Sites; Humans; Mutation; Phosphorylation; Proline; Receptors, Androgen; Sequence Deletion; Serine; Structure-Activity Relationship; Transcription, Genetic | 1995 |
A single point mutation decreases picrotoxinin sensitivity of the human GABA receptor rho 1 subunit.
Topics: Base Sequence; Bicuculline; Cell Line; Humans; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Point Mutation; Proline; Protein Structure, Tertiary; Receptors, GABA; Serine; Sesterterpenes | 1995 |
Influence of serine in position i on conformation and dynamics of reverse turns.
Topics: alpha-Amylases; Amino Acid Sequence; Computer Simulation; Enzyme Inhibitors; Molecular Sequence Data; Peptides; Peptides, Cyclic; Proline; Protein Conformation; Serine; Structure-Activity Relationship | 1995 |
Functional analysis of a proline to serine mutation in codon 453 of the thyroid hormone receptor beta 1 gene.
Topics: Adult; Amino Acid Sequence; Antisense Elements (Genetics); Base Sequence; Cell Line; Codon; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proline; Receptors, Thyroid Hormone; Serine | 1995 |
Functional domains of the heavy metal-responsive transcription regulator MTF-1.
Topics: Base Sequence; Binding Sites; DNA; DNA-Binding Proteins; Fungal Proteins; Gene Deletion; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Humans; Hydrogen-Ion Concentration; Metallothionein; Metals; Molecular Sequence Data; Mutagenesis; Plasmids; Proline; Promoter Regions, Genetic; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Zinc Fingers | 1995 |
A new transthyretin variant (Ser 24) associated with familial amyloid polyneuropathy.
Topics: Aged; Amyloid Neuropathies; Cardiomyopathies; Codon; Cytosine; DNA; Exons; Family Health; Female; Genetic Variation; Heterozygote; Humans; Male; Middle Aged; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prealbumin; Proline; Sequence Analysis, DNA; Serine; Thymine | 1995 |
Identification of a plant serine-arginine-rich protein similar to the mammalian splicing factor SF2/ASF.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Arabidopsis Proteins; Arginine; Base Sequence; Cloning, Molecular; DNA, Complementary; Exons; Humans; Lysine; Mammals; Molecular Sequence Data; Nuclear Proteins; Plant Proteins; Proline; Recombinant Proteins; RNA-Binding Proteins; Sequence Homology, Amino Acid; Serine; Serine-Arginine Splicing Factors; Spliceosomes | 1995 |
Rapid and sensitive procedure for the separation and quantitation of D- and L-serine in rat brain using gas chromatography-mass spectrometry.
Topics: Acylation; Animals; Brain Chemistry; Butanols; Capillary Action; Esterification; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Proline; Rats; Rats, Sprague-Dawley; Serine | 1995 |
Regional differences in pig gastric mucins.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Cardia; Dithiothreitol; Gastric Fundus; Gastric Mucins; Oligosaccharides; Oxidation-Reduction; Proline; Pylorus; Serine; Swine; Threonine | 1993 |
Compound heterozygous mutations affecting both hepatic and erythrocyte isozymes of pyruvate kinase.
Topics: Adult; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Consanguinity; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Female; Heterozygote; Humans; Isoenzymes; Liver; Male; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Proline; Pyruvate Kinase; Restriction Mapping; RNA, Messenger; Serine; Tryptophan | 1995 |
Mutations of the Connexin43 gap-junction gene in patients with heart malformations and defects of laterality.
Topics: Adolescent; Base Sequence; Cell Communication; Cell Line; Child; Child, Preschool; Connexin 43; DNA; Fibroblasts; Functional Laterality; Gap Junctions; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Molecular Sequence Data; Point Mutation; Proline; Serine; Transfection | 1995 |
Pattern dystrophy and retinitis pigmentosa caused by a peripherin/RDS mutation.
Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 6; Eye Proteins; Humans; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Middle Aged; Mutation; Nerve Tissue Proteins; Neuropeptides; Pedigree; Peripherins; Proline; Retina; Retinal Degeneration; Retinitis Pigmentosa; Serine | 1995 |
The p60 tumor necrosis factor (TNF) receptor-associated kinase (TRAK) binds residues 344-397 within the cytoplasmic domain involved in TNF signaling.
Topics: Binding Sites; Cell Line; Glutathione Transferase; Humans; Kinetics; Mutagenesis; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Restriction Mapping; Sequence Deletion; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 1995 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs.
Topics: alpha-Amylases; Amino Acids; Animals; Aspartic Acid; Dietary Fiber; Digestion; Feces; Glutamates; Glutamic Acid; Glycine; Ileum; Male; Pancreas; Pancreatic Juice; Pectins; Phenylalanine; Proline; Serine; Swine; Threonine; Trypsin; Valine | 1994 |
Differential processing of human and rat E1 alpha precursors of the branched-chain alpha-keto acid dehydrogenase complex caused by an N-terminal proline in the rat sequence.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acid Sequence; Animals; Binding Sites; Cattle; Humans; Ketone Oxidoreductases; Molecular Sequence Data; Multienzyme Complexes; Proline; Protein Precursors; Rats; Sequence Alignment; Serine | 1994 |
Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.
Topics: Asian People; Base Sequence; Cells, Cultured; Chimera; China; Chloramphenicol O-Acetyltransferase; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Gene Expression Regulation, Enzymologic; Haplotypes; Humans; Hydroxylation; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Open Reading Frames; Plasmids; Polymerase Chain Reaction; Proline; Restriction Mapping; Serine; White People | 1994 |
Novel antibiotics, amythiamicins. III. Structure elucidations of amythiamicins A, B and C.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Molecular Structure; Proline; Serine; Thiazoles | 1994 |
Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli.
Topics: Carrier Proteins; DNA Restriction Enzymes; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lithium; Mutagenesis; Plasmids; Potassium; Proline; Serine; Sodium; Sodium-Hydrogen Exchangers | 1993 |
The dopamine DA-1 receptor agonist fenoldopam enhances amino-acid-induced hyperemia in dogs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alanine; Amino Acids; Animals; Dogs; Dopamine Agents; Drug Synergism; Female; Fenoldopam; Glomerular Filtration Rate; Hyperemia; Proline; Renal Circulation; Serine; Sodium | 1993 |
Residue at position 331 in the IgG1 and IgG4 CH2 domains contributes to their differential ability to bind and activate complement.
Topics: Amino Acid Sequence; Animals; Antibodies; Base Sequence; Complement Activation; Complement C1q; Conserved Sequence; Hemolysis; Humans; Immunoglobulin G; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Plasmacytoma; Point Mutation; Proline; Protein Conformation; Recombinant Fusion Proteins; Restriction Mapping; Serine; Tumor Cells, Cultured | 1994 |
Synthesis of a glycopeptide with phytoalexin elicitor activity. I. Synthesis of a triglycosyl L-serine and a triglycosyl L-seryl-L-proline dipeptide.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Disaccharides; Glycopeptides; Glycosylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Optical Rotation; Phytoalexins; Plant Extracts; Proline; Serine; Sesquiterpenes; Stereoisomerism; Terpenes; Trisaccharides | 1994 |
Protein kinase FA/GSK-3 phosphorylates tau on Ser235-Pro and Ser404-Pro that are abnormally phosphorylated in Alzheimer's disease brain.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Glycogen Synthase Kinase 3; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Proline; Serine; tau Proteins | 1993 |
Functional studies of a germ-line polymorphism at codon 47 within the p53 gene.
Topics: Alleles; Base Sequence; Black People; Cloning, Molecular; Gene Frequency; Genes, p53; Humans; Immunohistochemistry; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Serine; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; United States; White People | 1993 |
Congenital plasminogen deficiency caused by a Ser572 to Pro mutation.
Topics: Adult; Base Sequence; Blotting, Southern; Cerebral Infarction; DNA Restriction Enzymes; Female; Humans; Japan; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Plasminogen; Polymerase Chain Reaction; Proline; Serine; Thrombosis | 1993 |
Equilibrium dissociation and unfolding of nucleoside diphosphate kinase from Dictyostelium discoideum. Role of proline 100 in the stability of the hexameric enzyme.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Circular Dichroism; Dictyostelium; Enzyme Stability; Glycine; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Oligodeoxyribonucleotides; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Urea | 1993 |
Isolation and characterization of male flower cDNAs from maize.
Topics: Amino Acid Sequence; Base Sequence; DNA, Complementary; Gene Expression; Gene Library; Genes, Plant; Glycine; Molecular Sequence Data; Peptides; Plant Proteins; Proline; Protein Sorting Signals; RNA, Messenger; Serine; Zea mays | 1993 |
Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Fertilization; Humans; Meiosis; Molecular Sequence Data; Mutagenesis; Oocytes; Phosphorylation; Proline; Proto-Oncogene Mas; Proto-Oncogene Proteins c-mos; Selection, Genetic; Serine; Ubiquitins; Xenopus | 1993 |
MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.
Topics: Adult; Amino Acid Sequence; Base Sequence; Cell Line; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 9; DNA, Complementary; Humans; Leukemia, Monocytic, Acute; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Oncogenes; Proline; RNA, Messenger; Serine; Transcription Factors; Translocation, Genetic | 1993 |
A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias.
Topics: Amino Acid Sequence; Base Sequence; Child; Chromosome Mapping; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Cloning, Molecular; DNA-Binding Proteins; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proline; Proto-Oncogenes; Recombinant Fusion Proteins; Serine; Transcription Factors; Transcription, Genetic; Translocation, Genetic; Zinc Fingers | 1993 |
Functional consequences of the Ser334-->Pro mutation in a human factor X variant (factor XMarseille).
Topics: Animals; Base Sequence; Calcium; Cattle; DNA; DNA Primers; Factor Va; Factor X; Factor X Deficiency; Factor Xa; Female; Humans; Middle Aged; Molecular Sequence Data; Phospholipids; Point Mutation; Proline; Prothrombin; Rabbits; Serine | 1995 |
Cell cycle-dependent phosphorylation and microtubule binding of tau protein stably transfected into Chinese hamster ovary cells.
Topics: Animals; Cell Cycle; CHO Cells; Cricetinae; Humans; Microtubules; Mitosis; Phosphorylation; Proline; Protein Binding; Serine; tau Proteins; Threonine; Transfection | 1995 |
O-glycosylation of a precursor to a sweet potato vacuolar protein, sporamin, expressed in tobacco cells.
Topics: 2,2'-Dipyridyl; Amino Acid Sequence; Base Sequence; Brefeldin A; Calcimycin; Carbohydrates; Cell Line; Cyclopentanes; DNA Primers; Glycoproteins; Glycosylation; Golgi Apparatus; Molecular Sequence Data; Monensin; Mutagenesis, Site-Directed; Nicotiana; Peptide Fragments; Plant Proteins; Plants, Toxic; Point Mutation; Proline; Protein Precursors; Protein Processing, Post-Translational; Protein Sorting Signals; Protein Synthesis Inhibitors; Recombinant Proteins; Serine; Transfection; Vacuoles; Vegetables | 1995 |
Improved biodistribution, tumor targeting, and reduced immunogenicity in mice with a gamma 4 variant of Campath-1H.
Topics: Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antibody-Dependent Cell Cytotoxicity; Cell Line; CHO Cells; Cricetinae; Female; Genetic Variation; Half-Life; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mutagenesis, Site-Directed; Neoplasms, Experimental; Point Mutation; Proline; Recombinant Proteins; Serine; Structure-Activity Relationship; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Effect of serine O-glycosylation on cis-trans proline isomerization.
Topics: Acetylglucosamine; Amino Acid Sequence; Glycopeptides; Glycosylation; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Proline; Protein Conformation; Serine; Stereoisomerism; Structure-Activity Relationship; Tyrosine | 1996 |
Pest sequences in EF-hand calcium-binding proteins.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Glutamic Acid; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Proline; S100 Proteins; Serine; Threonine | 1995 |
Substrates containing phosphorylated residues adjacent to proline decrease the cleavage by proline-specific peptidases.
Topics: Amino Acid Sequence; Anilides; Aniline Compounds; Animals; Dipeptides; Endopeptidases; Flavobacterium; Humans; Hydrolysis; Kinetics; Molecular Conformation; Molecular Sequence Data; Oligopeptides; Phosphorylation; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Serine; Serine Endopeptidases; Substrate Specificity; Swine; Threonine; Tyrosine | 1996 |
A novel point mutation in congenital erythropoietic porphyria in two members of Japanese family.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; DNA Primers; Female; Genes, Recessive; Humans; Japan; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Porphyria, Erythropoietic; Proline; Serine; Uroporphyrinogen III Synthetase | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Ser57 in the Na+/proline permease of Escherichia coli is critical for high-affinity proline uptake.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Binding Sites; Biological Transport; Cell Compartmentation; Escherichia coli; Genetic Complementation Test; Kinetics; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Proline; Sequence Analysis, DNA; Serine | 1996 |
Ser72Pro active-site disease mutation in human lysosomal aspartylglucosaminidase: abnormal intracellular processing and evidence for extracellular activation.
Topics: Animals; Aspartylglucosylaminase; Binding Sites; Cell Line, Transformed; Chlorocebus aethiops; Endopeptidases; Endoplasmic Reticulum; Humans; Lysosomal Storage Diseases; Lysosomes; Point Mutation; Proline; Protein Processing, Post-Translational; Serine | 1996 |
The molecular basis of alkaptonuria.
Topics: Alkaptonuria; Amino Acid Sequence; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 3; Cloning, Molecular; Dioxygenases; DNA, Complementary; Female; Homogentisate 1,2-Dioxygenase; Humans; Male; Molecular Sequence Data; Oxygenases; Point Mutation; Proline; Serine; Tissue Distribution | 1996 |
Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain.
Topics: Alanine; Animals; Avian Myeloblastosis Virus; Binding Sites; Cell Line; Chlorocebus aethiops; DNA; Gene Expression Regulation; Mice; Molecular Weight; Phosphorylation; Proline; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Serine; Structure-Activity Relationship; Trans-Activators; Transcription, Genetic; Transcriptional Activation | 1996 |
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Female; Glycine; Histidine; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymerase Chain Reaction; Proline; Recombinant Proteins; Serine; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Characterization of recombinant human coagulation factor XFriuli.
Topics: 1-Carboxyglutamic Acid; Aspartic Acid; Base Sequence; Binding Sites; Cell Line; DNA, Complementary; Enzyme Activation; Factor X; Hemorrhagic Disorders; Humans; Hydrogen Bonding; Kidney; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Processing, Post-Translational; Protein Structure, Secondary; Recombinant Proteins; Serine; Transfection | 1996 |
Directed mutagenesis, Ser-56 to Pro, of Bacillus subtilis phosphatidylserine synthase drastically lowers enzymatic activity and relieves amplification toxicity in Escherichia coli.
Topics: Alleles; Amino Acid Sequence; Bacillus subtilis; CDPdiacylglycerol-Serine O-Phosphatidyltransferase; Conserved Sequence; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Serine | 1996 |
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Extracellular Matrix Proteins; Fibrinogen; Genetic Complementation Test; Humans; Integrin beta3; Molecular Sequence Data; Oligopeptides; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Proline; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Sequence Alignment; Serine; Signal Transduction; Thrombasthenia; Transfection; Vitronectin; von Willebrand Factor | 1996 |
Characterization of herpes simplex virus type 1 recombinants with mutations in the cytoplasmic tail of glycoprotein H.
Topics: Alanine; Animals; Binding Sites; Cell Line; Chlorocebus aethiops; COS Cells; Herpesvirus 1, Human; Humans; Mutation; Point Mutation; Proline; Recombination, Genetic; Sequence Deletion; Serine; Structure-Activity Relationship; Valine; Vero Cells; Viral Envelope Proteins; Viral Plaque Assay | 1996 |
The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers.
Topics: Amino Acid Sequence; Animals; Base Sequence; Connectin; DNA, Complementary; Epitope Mapping; Gene Dosage; Genetic Variation; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Muscle Proteins; Proline; Protein Kinases; Rabbits; Repetitive Sequences, Nucleic Acid; Sequence Homology, Amino Acid; Serine | 1996 |
Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments.
Topics: Animals; Electroretinography; Genes, Dominant; Humans; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Electron; Microscopy, Electron, Scanning; Point Mutation; Proline; Retinal Degeneration; Rhodopsin; Rod Cell Outer Segment; Serine | 1996 |
Repression of human heat shock factor 1 activity at control temperature by phosphorylation.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Heat Shock Transcription Factors; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Proline; Serine; Temperature; Transcription Factors | 1996 |
Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: analysis on tau protein.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; CDC2 Protein Kinase; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heparin; Molecular Sequence Data; Peptides; Phosphorylation; Proline; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Substrate Specificity; tau Proteins; Threonine | 1996 |
Substitutions of Ser for Asn-163 and Pro for Leu-264 are important for stabilization of lipase from Pseudomonas aeruginosa.
Topics: Aspartic Acid; Enzyme Stability; Hydrogen-Ion Concentration; Leucine; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein Conformation; Pseudomonas aeruginosa; Restriction Mapping; Serine | 1996 |
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil | 1996 |
Genotype-phenotype correlation for nucleotide substitutions in the IgII-IgIII linker of FGFR2.
Topics: Adult; Child; Craniosynostoses; Dipeptides; Female; Foot Deformities, Congenital; Genotype; Hand Deformities, Congenital; Humans; Immunoglobulins; Male; Nucleotides; Pedigree; Phenotype; Proline; Radiography; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Serine | 1997 |
Identification of Ser-Pro and Thr-Pro phosphorylation sites in chicken neurofilament-M tail domain.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Chick Embryo; Chickens; Electrophoresis, Polyacrylamide Gel; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Neurofilament Proteins; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Proline; Protein Structure, Tertiary; Serine; Threonine | 1997 |
Altered Rous sarcoma virus Gag polyprotein processing and its effects on particle formation.
Topics: Animals; Avian Sarcoma Viruses; Binding Sites; COS Cells; Defective Viruses; Endopeptidases; Gene Products, gag; Glycine; Mutagenesis; Nucleocapsid; Proline; Protein Precursors; Protein Processing, Post-Translational; Proteins; Serine; Valine; Virion; Virus Assembly | 1997 |
Bond-specific chemical cleavages of peptides and proteins with perfluoric acid vapors: novel peptide bond cleavages of glycyl-threonine, the amino side of serine residues and the carboxyl side of aspartic acid residues.
Topics: Amino Acid Sequence; Aspartic Acid; Fluorocarbons; Glycine; Molecular Sequence Data; Peptides; Proline; Proteins; Serine; Threonine | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Transformation, Neoplastic; Drug Resistance, Microbial; Humans; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Proline; Proto-Oncogene Proteins c-fos; Serine; Signal Transduction; Structure-Activity Relationship; Transcription Factor AP-1; Transcription, Genetic | 1997 |
Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; COS Cells; DNA Primers; Genes, Dominant; Genes, MHC Class II; GTP-Binding Proteins; Humans; Mutagenesis, Site-Directed; Nuclear Proteins; Oligopeptides; Peptides; Proline; Promoter Regions, Genetic; Sequence Deletion; Serine; Threonine; Trans-Activators; Transfection; Tumor Cells, Cultured | 1997 |
A serine-to-proline mutation in the copper-transporting P-type ATPase gene of the macular mouse.
Topics: Adenosine Triphosphatases; Animals; Carrier Proteins; Cation Transport Proteins; Copper-Transporting ATPases; Deoxyribonuclease BamHI; Disease Models, Animal; Female; Homozygote; Humans; Male; Menkes Kinky Hair Syndrome; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Point Mutation; Proline; Recombinant Fusion Proteins; Sequence Analysis, DNA; Serine | 1997 |
Antigenic variability of an immunodominant region (239-261) of the surface glycoprotein of HTLV-I.
Topics: Amino Acid Sequence; Antigenic Variation; Epitopes; HTLV-I Antibodies; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Molecular Sequence Data; Peptides; Point Mutation; Proline; Serine | 1997 |
Antibodies directed against a variable and neutralizable region of the HTLV-I envelope surface glycoprotein.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigenic Variation; Cell Line; Epitopes; Gene Products, env; Human T-lymphotropic virus 1; Humans; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Peptide Fragments; Proline; Retroviridae Proteins, Oncogenic; Serine; Tumor Cells, Cultured | 1997 |
Severe proximal deep vein thrombosis in a Glanzmann thrombasthenia variant successfully treated with a low molecular weight heparin.
Topics: Aged; Anticoagulants; Femoral Vein; Genetic Variation; Heparin, Low-Molecular-Weight; Humans; Male; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Popliteal Vein; Proline; Serine; Thrombasthenia; Thrombosis | 1997 |
Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.
Topics: Animals; Biological Factors; Cell Line; Genetic Variation; HIV Envelope Protein gp120; Humans; Macrophages, Alveolar; Membrane Fusion; Membrane Glycoproteins; Proline; Receptors, CCR5; Receptors, Cytokine; Receptors, HIV; Serine; Simian Immunodeficiency Virus; T-Lymphocytes; Viral Envelope Proteins; Virus Replication | 1997 |
Maintenance threonine requirement and efficiency of its use for accretion of whole-body threonine and protein in young chicks.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cystine; Energy Intake; Glycine; Male; Nutritional Requirements; Proline; Proteins; Regression Analysis; Serine; Threonine; Weight Gain | 1997 |
Extensible collagen in mussel byssus: a natural block copolymer.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Biopolymers; Bivalvia; Collagen; DNA, Complementary; Elasticity; Elastin; Fibroins; Glycine; Histidine; Molecular Sequence Data; Proline; Protein Conformation; Protein Precursors; Protein Structure, Secondary; Sequence Alignment; Serine | 1997 |
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine | 1997 |
O-Glycosylation of C-terminal tandem-repeated sequences regulates the secretion of rat pancreatic bile salt-dependent lipase.
Topics: Amino Acid Sequence; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; DNA Probes; Galactose; Glutamic Acid; Glycosylation; Kinetics; Lipase; Monensin; Pancreas; Peptide Fragments; Proline; Rats; Recombinant Proteins; Serine; Sterol Esterase; Threonine; Transfection | 1997 |
Phosphorylation regulates the microtubule-destabilizing activity of stathmin and its interaction with tubulin.
Topics: Animals; Binding Sites; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cloning, Molecular; Cross-Linking Reagents; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Humans; Kinetics; Microtubule Proteins; Microtubules; Phosphoproteins; Phosphorylation; Phosphoserine; Proline; Protein Kinases; Recombinant Proteins; Serine; Stathmin; Swine; Tubulin | 1997 |
Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5.
Topics: CDC2 Protein Kinase; Computer Simulation; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Kinetics; Oligopeptides; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Pyrrolidines; Serine; Substrate Specificity; Vimentin | 1997 |
The FEL (AF-4) protein donates transcriptional activation sequences to Hrx-Fel fusion proteins in leukemias containing T(4;11)(Q21;Q23) chromosomal translocations.
Topics: Adenoviridae; Adenovirus E1B Proteins; Amino Acid Sequence; Animals; Binding Sites; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; COS Cells; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proline; Proto-Oncogenes; Restriction Mapping; Serine; Transcription Factors; Transcriptional Activation; Transcriptional Elongation Factors; Transfection; Translocation, Genetic; Tumor Cells, Cultured; Zinc Fingers | 1997 |
The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus.
Topics: Amino Acid Sequence; Animals; Antibodies; Binding Sites; Carrier Proteins; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Polyenes; Proline; Rats; Serine; Sirolimus; Substrate Specificity; Threonine | 1997 |
A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit.
Topics: Amino Acid Sequence; Animals; Cell Line; Cholesterol; Cricetinae; Membrane Fusion; Molecular Sequence Data; Point Mutation; Proline; Semliki forest virus; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Viral Envelope Proteins; Virus Replication | 1998 |
A novel point mutation at position 156 of reverse transcriptase from feline immunodeficiency virus confers resistance to the combination of (-)-beta-2',3'-dideoxy-3'-thiacytidine and 3'-azido-3'-deoxythymidine.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cats; Cell Line; Drug Interactions; Drug Resistance, Microbial; Immunodeficiency Virus, Feline; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Serine; Viral Plaque Assay; Zidovudine | 1998 |
A single conserved amino acid in the coat protein gene of pea seed-borne mosaic potyvirus modulates the ability of the virus to move systemically in Chenopodium quinoa.
Topics: Amino Acid Sequence; Capsid; Chenopodiaceae; Conserved Sequence; Edible Grain; Molecular Sequence Data; Mutation; Pisum sativum; Potyvirus; Proline; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Virion | 1998 |
Processing of the presequence of the Schizosaccharomyces pombe Rieske iron-sulfur protein occurs in a single step and can be converted to two-step processing by mutation of a single proline to serine in the presequence.
Topics: Amino Acid Sequence; Electron Transport Complex III; Endopeptidase K; Iron-Sulfur Proteins; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurospora crassa; Point Mutation; Proline; Protein Precursors; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Schizosaccharomyces; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 1998 |
Role of phosphorylation in determining the backbone dynamics of the serine/threonine-proline motif and Pin1 substrate recognition.
Topics: Animals; Catalysis; Cattle; Hydrogen-Ion Concentration; Isomerism; Kinetics; NIMA-Interacting Peptidylprolyl Isomerase; Oligopeptides; Osmolar Concentration; Peptidylprolyl Isomerase; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Proline; Protein Conformation; Serine; Substrate Specificity; Threonine | 1998 |
A single amino acid substitution in yeast eIF-5A results in mRNA stabilization.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Eukaryotic Translation Initiation Factor 5A; Fungal Proteins; Genes, Fungal; Molecular Sequence Data; Mutagenesis; Peptide Initiation Factors; Proline; Protein Biosynthesis; RNA Precursors; RNA-Binding Proteins; RNA, Fungal; RNA, Messenger; Serine; Temperature; Yeasts | 1998 |
Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern children with growth hormone, prolactin, and thyrotropin deficiency.
Topics: Codon; DNA; DNA-Binding Proteins; Female; Human Growth Hormone; Humans; Infant; Male; Pedigree; Point Mutation; Polymerase Chain Reaction; Prolactin; Proline; Protein Structure, Secondary; Saudi Arabia; Serine; Thyrotropin; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 1998 |
A family with Liddle's syndrome caused by a new missense mutation in the beta subunit of the epithelial sodium channel.
Topics: Adult; Alleles; Base Sequence; Codon; DNA; Epithelium; Female; Humans; Hypertension; Male; Mutagenesis; Pedigree; Point Mutation; Polymerase Chain Reaction; Proline; Sequence Analysis, DNA; Serine; Sodium Channels; Syndrome | 1998 |
Specific single or double proline substitutions in the "spring-loaded" coiled-coil region of the influenza hemagglutinin impair or abolish membrane fusion activity.
Topics: Animals; Cell Line; Cell Membrane; COS Cells; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Membrane Fusion; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Processing, Post-Translational; Serine; Valine | 1998 |
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Core Binding Factor Alpha 1 Subunit; COS Cells; Dimerization; DNA-Binding Proteins; Glutamine; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Localization Signals; Proline; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation | 1998 |
Molecular diagnosis of alkaptonuria mutation by analysis of homogentisate 1,2 dioxygenase mRNA from urine and blood.
Topics: Alkaptonuria; Amino Acid Substitution; Dioxygenases; Female; Homogentisate 1,2-Dioxygenase; Humans; Male; Oxygenases; Pedigree; Point Mutation; Proline; RNA, Messenger; Serine | 1998 |
Identification of a naturally occurring Pro15-Ser15 substitution in the serotonin5A receptor gene in alcoholics and healthy volunteers.
Topics: Alcoholism; Amino Acid Substitution; DNA Primers; Exons; Gene Frequency; Humans; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Receptors, Serotonin; Reference Values; Serine | 1998 |
Dual amino acid-selective and site-directed stable-isotope labeling of the human c-Ha-Ras protein by cell-free synthesis.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbon Isotopes; Carbon Radioisotopes; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Humans; Isotope Labeling; Models, Chemical; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oncogene Proteins v-raf; Proline; ras Proteins; Retroviridae Proteins, Oncogenic; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 1998 |
A Pro504 --> Ser substitution in the beta-subunit of beta-hexosaminidase A inhibits alpha-subunit hydrolysis of GM2 ganglioside, resulting in chronic Sandhoff disease.
Topics: Amino Acid Substitution; Animals; Base Sequence; beta-N-Acetylhexosaminidases; CHO Cells; Chronic Disease; Cricetinae; DNA Primers; G(M2) Ganglioside; Heterozygote; Hexosaminidase A; Hexosaminidase B; Homozygote; Humans; Hydrolysis; Proline; Sandhoff Disease; Serine | 1998 |
Interactions of proline, serine, and leucine with isolated spinach thylakoids: solute loading during freezing is not related to membrane fluidity.
Topics: Leucine; Membrane Fluidity; Membrane Proteins; Plant Proteins; Proline; Protein Binding; Serine; Spinacia oleracea | 1998 |
Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Cytochrome P-450 Enzyme System; Heme; Humans; Hydroxylation; Insecta; Lauric Acids; Mutagenesis, Site-Directed; Proline; Rabbits; Rats; Serine; Steroid Hydroxylases; Testosterone | 1998 |
Membrane cofactor protein: importance of N- and O-glycosylation for complement regulatory function.
Topics: Animals; Antigens, CD; Asparagine; Cell Fractionation; CHO Cells; Clone Cells; Complement Activation; Complement C3b; Complement C4b; Cricetinae; Cytoprotection; Glutamine; Glycosylation; Humans; Hydrolysis; Kinetics; Membrane Cofactor Protein; Membrane Glycoproteins; Mutagenesis, Site-Directed; Proline; Protein Structure, Tertiary; Sequence Deletion; Serine; Threonine; Transfection | 1998 |
Spin trapping for nitric oxide produced in LPS-treated mouse using various new dithiocarbamate iron complexes having substituted proline and serine moiety.
Topics: Amino Acid Substitution; Animals; Ferrous Compounds; Injections, Intravenous; Lipopolysaccharides; Liver; Mice; Nitric Oxide; Proline; Serine; Spin Trapping; Thiocarbamates | 1998 |
Allostery in rabbit pyruvate kinase: development of a strategy to elucidate the mechanism.
Topics: Allosteric Regulation; Animals; Binding Sites; Circular Dichroism; Energy Metabolism; Kidney; Kinetics; Lysine; Mathematical Computing; Models, Molecular; Muscle, Skeletal; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Conformation; Protein Structure, Secondary; Pyruvate Kinase; Rabbits; Recombinant Proteins; Serine; Structure-Activity Relationship; Tyrosine; Ultracentrifugation | 1998 |
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Caseins; COS Cells; DNA; DNA-Binding Proteins; Genes, Reporter; Milk Proteins; Molecular Sequence Data; Phosphoamino Acids; Phosphorylation; Prolactin; Proline; Serine; STAT5 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation | 1998 |
Determinants of strand register in antiparallel beta-sheets of proteins.
Topics: Binding Sites; Computer Simulation; Cysteine; Disulfides; Hydrogen Bonding; Isoleucine; Models, Molecular; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Serine; Threonine; Valine | 1998 |
Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen.
Topics: Alanine; Animals; Antigens, CD; Cell Adhesion; Cell Count; Cell Line; Cricetinae; Cytoskeleton; Fibrinogen; Humans; Image Processing, Computer-Assisted; Integrin beta3; Kinetics; Platelet Membrane Glycoproteins; Point Mutation; Proline; Serine; von Willebrand Factor | 1998 |
Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase.
Topics: Amino Acid Sequence; Animals; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Line, Transformed; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drosophila; Drosophila Proteins; Enzyme Inhibitors; Glutathione Transferase; HeLa Cells; Herpesvirus 3, Human; Humans; Jurkat Cells; Molecular Sequence Data; Phosphorylation; Positive Transcriptional Elongation Factor B; Proline; Protein Serine-Threonine Kinases; Purines; Receptors, Fc; Recombinant Fusion Proteins; Roscovitine; Serine; Threonine; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins | 1999 |
A Pro51Ser mutation in the COCH gene is associated with late onset autosomal dominant progressive sensorineural hearing loss with vestibular defects.
Topics: Age of Onset; Amino Acid Substitution; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 14; Deafness; DNA; DNA Mutational Analysis; Extracellular Matrix Proteins; Female; Genes, Dominant; Genetic Linkage; Hearing Loss, Sensorineural; Humans; Male; Microsatellite Repeats; Pedigree; Point Mutation; Proline; Proteins; Serine; Vestibular Diseases | 1999 |
Conformational unfolding studies of three-disulfide mutants of bovine pancreatic ribonuclease A and the coupling of proline isomerization to disulfide redox reactions.
Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Cysteine; Disulfides; Mutagenesis, Site-Directed; Oxidation-Reduction; Proline; Protein Conformation; Protein Folding; Protein Isoforms; Ribonuclease, Pancreatic; Serine; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains.
Topics: Animals; Cell Polarity; Cells, Cultured; Humans; Insecta; Neurites; Phosphoproteins; Phosphorylation; Proline; Recombinant Proteins; Repetitive Sequences, Amino Acid; Serine; tau Proteins; Transfection | 1999 |
The role of water in the catalytic efficiency of triosephosphate isomerase.
Topics: Animals; Binding Sites; Catalysis; Chickens; Crystallography, X-Ray; Kinetics; Mutagenesis, Site-Directed; Proline; Protein Conformation; Serine; Substrate Specificity; Triose-Phosphate Isomerase; Water | 1999 |
SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1.
Topics: Amino Acid Sequence; Amino Acids; Animals; Base Sequence; DNA Primers; DNA-Binding Proteins; Enhancer Elements, Genetic; Mice; Mutagenesis, Site-Directed; Proline; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fes; Serine; Structure-Activity Relationship; Threonine; Trans-Activators; Transcription Factors; Transcriptional Activation | 1999 |
Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).
Topics: Adult; Alleles; alpha 1-Antitrypsin; Animals; Child; Female; Gene Expression; Humans; Isoleucine; Leucine; Male; Mice; Pedigree; Proline; Serine; Serine Proteinase Inhibitors; Threonine | 1999 |
Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Eye Proteins; Homeodomain Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Paired Box Transcription Factors; PAX6 Transcription Factor; Phosphorylation; Proline; Repressor Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Zebrafish | 1999 |
Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Cattle; DNA Helicases; DNA Replication; DNA-Binding Proteins; Glutamic Acid; Glutamine; Humans; Lysine; Magnesium; Papillomaviridae; Proline; Replication Origin; Saccharomyces cerevisiae; Serine; Temperature; Viral Proteins; Virus Replication | 1999 |
Two novel missense mutations causing adrenoleukodystrophy in Italian patients.
Topics: Adrenoleukodystrophy; Adult; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Child; Female; Humans; Italy; Leucine; Male; Membrane Proteins; Mutation, Missense; Pedigree; Proline; Serine | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Point Mutation; Proline; Reverse Transcriptase Inhibitors; Serine | 1999 |
Expression, DNA-binding specificity and transcriptional regulation of nuclear factor 1 family proteins from rat.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cloning, Molecular; DNA; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; Multigene Family; NFI Transcription Factors; Nuclear Proteins; Proline; Protein Isoforms; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Serine; Transcription Factors; Transfection; Y-Box-Binding Protein 1 | 1999 |
The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter.
Topics: Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Guanine; Homeodomain Proteins; Mice; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Osteoblasts; Osteocalcin; Peptide Fragments; Proline; Promoter Regions, Genetic; Rats; Repressor Proteins; RNA-Binding Proteins; Serine; Thymine; Trans-Activators | 1999 |
Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity.
Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Arginine; Catalysis; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Glutamic Acid; Glutamine; Glycine; Humans; Isoenzymes; Mutagenesis, Site-Directed; Proline; Serine; Teniposide; Tumor Cells, Cultured | 1999 |
Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity.
Topics: Adolescent; Adult; Alcoholism; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Benzodiazepines; Child of Impaired Parents; Diazepam; Ethanol; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Pharmacogenetics; Pilot Projects; Polymorphism, Genetic; Proline; Pursuit, Smooth; Rats; Receptors, GABA-A; Saccades; Serine | 1999 |
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
Topics: Amino Acid Sequence; Binding, Competitive; Cell Line; Humans; Membrane Proteins; Molecular Sequence Data; Muscarinic Agonists; Mutation; Proline; Protein Conformation; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Serine; Threonine; Tyrosine | 1999 |
A novel subtype of class II alcohol dehydrogenase in rodents. Unique Pro(47) and Ser(182) modulates hydride transfer in the mouse enzyme.
Topics: Alcohol Dehydrogenase; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Evolution, Molecular; Humans; Hydrogen; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Proline; Protein Conformation; Rats; Serine | 1999 |
Familial dementia caused by polymerization of mutant neuroserpin.
Topics: Biopolymers; Cerebral Cortex; Dementia; Female; Humans; Inclusion Bodies; Male; Neuropeptides; Neuroserpin; Point Mutation; Proline; Serine; Serpins | 1999 |
Different ocular abnormalities in individuals of a three-generation family caused by a new nonsense mutation in the PST domain of the PAX6 gene. Mutations in brief no. 189. Online.
Topics: Aniridia; Codon, Nonsense; DNA-Binding Proteins; Eye Proteins; Homeodomain Proteins; Humans; Mutation; Paired Box Transcription Factors; PAX6 Transcription Factor; Proline; Repressor Proteins; Serine; Threonine | 1998 |
Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Proline; Protein Binding; Pyridines; Serine; Threonine; Viscosity | 2000 |
Conformation of the RNA polymerase II C-terminal domain: circular dichroism of long and short fragments.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Aminoisobutyric Acids; Animals; Binding Sites; Circular Dichroism; Conserved Sequence; Hydrogen Bonding; Mice; Molecular Weight; Peptide Fragments; Phosphorylation; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; RNA Polymerase II; Serine; Solvents; Temperature; Trifluoroethanol; Tyrosine; Water | 2000 |
Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene.
Topics: Carcinogens; Cocarcinogenesis; Connexins; DNA, Neoplasm; Gap Junction alpha-4 Protein; Hemangiosarcoma; Humans; Liver Neoplasms; Mutation; Occupational Diseases; Occupational Exposure; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Serine; Thorium Dioxide; Vinyl Chloride | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.
Topics: Amino Acid Sequence; Animals; Binding Sites; Glutamic Acid; Humans; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Mutagenesis; Phosphorylation; Polymers; Proline; Serine; Swine; Tubulin | 2000 |
A novel Ser O-glucuronidation in acidic proline-rich proteins identified by tandem mass spectrometry.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Glucuronic Acid; Humans; Mass Spectrometry; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Protein Processing, Post-Translational; Serine; Time Factors; Trypsin | 2000 |
Specific Ser-Pro phosphorylation by the RNA-recognition motif containing kinase KIS.
Topics: Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; DNA, Complementary; Escherichia coli; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Myelin Basic Protein; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; RNA; Sequence Analysis, Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Synapsins; Threonine; Time Factors | 2000 |
Identification of a naturally occurring Pro385-Ser385 substitution in the GABA(A) receptor alpha6 subunit gene in alcoholics and healthy volunteers.
Topics: Alcoholism; Amino Acid Substitution; Animals; Finland; Genetic Variation; Humans; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Rats; Receptors, GABA-A; Reference Values; Serine; White People | 2000 |
The enamel protein amelogenin binds to the N-acetyl-D-glucosamine-mimicking peptide motif of cytokeratins.
Topics: Acetylglucosamine; Amelogenin; Amino Acid Motifs; Animals; Binding Sites; Binding, Competitive; Dental Enamel Proteins; Dose-Response Relationship, Drug; Genetic Linkage; Hemagglutinins; Humans; Keratins; Kinetics; Mice; Models, Chemical; Peptides; Phenylalanine; Proline; Protein Binding; Serine; Time Factors; Tyrosine; X Chromosome | 2000 |
Five novel genetic variants in the promoter and coding region of the alpha B-crystallin gene (CRYAB): -652G>A, -650C>G, -249G>C, S41Y, P51L.
Topics: Amino Acid Substitution; Crystallins; Exons; Genetic Variation; Humans; Leucine; Mutation, Missense; Polymorphism, Genetic; Proline; Promoter Regions, Genetic; Serine; Tyrosine | 2000 |
Comparative sequence analysis identified mutations outside the NSP4 cytotoxic domain of tissue culture-adapted ATCC-Wa strain of human rotavirus and a novel inter-species variable domain in its C-terminus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Cattle; Cell Line; Cloning, Molecular; DNA-Directed RNA Polymerases; Genome, Viral; Humans; Isoelectric Point; Leucine; Macaca; Molecular Sequence Data; Mutation; Proline; Rotavirus; Serine; Swine; Viral Nonstructural Proteins | 2000 |
Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc.
Topics: Amino Acid Motifs; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; DNA; DNA-Binding Proteins; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Proline; Serine; Transcription Factors; Transfection; Tumor Cells, Cultured | 2001 |
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Topics: Analgesics, Opioid; Animals; Asparagine; Aspartic Acid; Cells, Cultured; COS Cells; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutagenesis, Site-Directed; Narcotics; Polymorphism, Single Nucleotide; Proline; Receptors, Opioid, mu; Serine; Signal Transduction; Sulfur Radioisotopes | 2001 |
Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
Topics: Alanine; Benzimidazoles; Binding Sites; Carbolines; Carboxylic Acids; Dipeptides; Isoquinolines; Kinetics; Ligands; Peptides; Proline; Propionates; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, mu; Serine; Tetrahydroisoquinolines; Tyrosine | 2000 |
Amino acid residues conferring herbicide tolerance in tobacco acetolactate synthase.
Topics: Acetolactate Synthase; Alanine; Amino Acid Substitution; Drug Tolerance; Enzyme Induction; Herbicides; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Nicotiana; Plants, Toxic; Proline; Pyrimidines; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfonylurea Compounds; Triazoles | 2000 |
Ser186Pro mutation of RHO gene in a Spanish autosomal dominant retinitis pigmentosa (ADRP) family.
Topics: Adult; DNA Mutational Analysis; Electroretinography; Female; Fundus Oculi; Genes, Dominant; Genotype; Humans; Male; Middle Aged; Pedigree; Phenotype; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proline; Retinitis Pigmentosa; Rhodopsin; Serine; Spain; Visual Fields | 2000 |
The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.
Topics: Amino Acid Sequence; Animals; Calcium; Calcium-Binding Proteins; Cell Line; Circular Dichroism; Cloning, Molecular; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Family Health; Glutamic Acid; Guanylate Cyclase-Activating Proteins; Hot Temperature; Humans; Leucine; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myristic Acids; Phenotype; Proline; Retinitis Pigmentosa; Sequence Homology, Amino Acid; Serine; Temperature | 2001 |
T>C transition in codon 72 (TCG-->CCG), S72P, a putative hotspot in PMP22.
Topics: Amino Acid Substitution; Codon; Cytosine; Hereditary Sensory and Motor Neuropathy; Humans; Mutation, Missense; Myelin Proteins; Proline; Serine; Thymine | 2001 |
Database analysis of O-glycosylation sites in proteins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Databases, Factual; Glycosylation; Mucins; Proline; Proteins; Serine; Threonine | 2001 |
The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.
Topics: Alanine; Amino Acid Motifs; Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Chromatography, High Pressure Liquid; Electrophysiology; Endotoxins; Glycine; Hemolysin Proteins; Manduca; Microvilli; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Proline; Protein Structure, Secondary; Serine; Temperature; Time Factors | 2001 |
Functional analysis of activation and repression domains of the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNT) protein isoforms.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; DNA-Binding Proteins; Gene Deletion; Oncorhynchus mykiss; Proline; Protein Isoforms; Protein Structure, Tertiary; Receptors, Aryl Hydrocarbon; Serine; Signal Transduction; Threonine; Transcription Factors; Transcriptional Activation; Xenobiotics | 1999 |
Differences in proliferation of the hematopoietic cell line TF-1 and cytokine production by peripheral blood leukocytes induced by 2 naturally occurring forms of human IL-3.
Topics: Cell Line; Cytokines; Hematopoietic Stem Cells; Humans; Interleukin-3; Leukocytes; Proline; Recombinant Proteins; Serine; Tumor Necrosis Factor-alpha | 2001 |
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
Topics: Animals; Binding Sites; Brain; Calcineurin; Carrier Proteins; CDC2 Protein Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; N-Methylaspartate; Phosphoprotein Phosphatases; Phosphorylation; Proline; Protein Phosphatase 1; Rabbits; Rats; Recombinant Proteins; RNA-Binding Proteins; Serine; Time Factors | 2001 |
Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Histidine; Humans; Hydroxylation; Isoleucine; Kinetics; Mephenytoin; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Recombinant Fusion Proteins; Serine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Threonine | 2001 |
Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis-trans isomerase Pin1.
Topics: Amino Acid Motifs; Blotting, Western; Calcineurin; Calcium; cis-trans-Isomerases; DNA-Binding Proteins; Doxycycline; Glutathione Transferase; Humans; Ionomycin; Jurkat Cells; Lymphocyte Activation; NFATC Transcription Factors; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Proteins; Peptidylprolyl Isomerase; Phosphorylation; Plasmids; Proline; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 2001 |
Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).
Topics: Amino Acids; Anti-Bacterial Agents; Arginine; Ascomycota; Cations, Divalent; Chromatography, High Pressure Liquid; Echinocandins; Fermentation; Hydroxyproline; Peptides; Peptides, Cyclic; Proline; Serine; Threonine; Trace Elements | 2001 |
IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Nucleus; Cloning, Molecular; Cytoplasm; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutamic Acid; HeLa Cells; Humans; I-kappa B Proteins; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Localization Signals; Plasmids; Proline; Protein Binding; Serine; Signal Transduction; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2001 |
A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols.
Topics: Alcohols; Alleles; beta-Galactosidase; Butanols; Chromosome Mapping; Diploidy; Eukaryotic Initiation Factor-2B; Evolution, Molecular; Genes, Reporter; Genetic Variation; Guanine; Immunoblotting; Lac Operon; Meiosis; Methionine; Models, Biological; Pentanols; Phenotype; Phosphorylation; Plasmids; Precipitin Tests; Proline; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Sucrose; Time Factors | 2001 |
Sequence analysis of fibroblast growth factor receptor 2 ( FGFR2 ) in Japanese patients with craniosynostosis.
Topics: Acrocephalosyndactylia; Arginine; Cleft Palate; Codon; Craniofacial Dysostosis; Craniosynostoses; Exons; Female; Heterozygote; Humans; Japan; Male; Mutation; Polymerase Chain Reaction; Proline; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Sequence Analysis, DNA; Serine; Syndactyly; Tryptophan | 2001 |
Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases.
Topics: Alanine; Animals; Arginine; Dyrk Kinases; Eukaryotic Initiation Factor-2B; Peptides; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Serine; Substrate Specificity | 2002 |
Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
Topics: Allosteric Site; Binding Sites; Computer Simulation; Crystallography, X-Ray; Glycerophosphates; Glycine; Hydrogen Bonding; Indoles; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Tryptophan Synthase | 2002 |
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Topics: Animals; Cell Differentiation; Cytoskeletal Proteins; Epithelial Cells; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kidney Diseases, Cystic; Leukemia, B-Cell; Lymphoma, B-Cell; Male; Mice; Mice, Mutant Strains; Paxillin; Phosphoproteins; Phosphorylation; Pregnancy; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Threonine | 2002 |
Identification of a novel NOG gene mutation (P35S) in an Italian family with symphalangism.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bone Morphogenetic Proteins; Carrier Proteins; Chromosomes, Human, Pair 17; Female; Finger Joint; Haplotypes; Humans; Italy; Male; Molecular Sequence Data; Mutation; Proline; Protein Structure, Secondary; Proteins; Serine; Toe Joint | 2002 |
Recognition of hybrid peptidyl carrier proteins/acyl carrier proteins in nonribosomal peptide synthetase modules by the 4'-phosphopantetheinyl transferases AcpS and Sfp.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Circular Dichroism; Escherichia coli; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Peptide Synthases; Peptides; Phenylalanine; Plasmids; Proline; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) | 2002 |
DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.
Topics: Amino Acid Motifs; Amino Acid Substitution; Apoptosis; Aspartic Acid; Calpain; DNA Damage; DNA Ligase ATP; DNA Ligases; Humans; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Proline; Recombinant Proteins; Serine; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Xenopus Proteins | 2002 |
Quantification of the influence of HPrSer46P on CcpA-cre interaction.
Topics: Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Base Sequence; Blotting, Western; DNA-Binding Proteins; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Fructosediphosphates; Gene Expression Regulation, Bacterial; Glucose-6-Phosphate; Macromolecular Substances; NADP; Operon; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Proline; Protein Binding; Repressor Proteins; Response Elements; Serine; Surface Plasmon Resonance; Thermodynamics; Time Factors | 2002 |
Incorporation of Ahc into model dipeptides as an inducer of a beta-turn with a distorted amide bond. Conformational analysis.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; Catalysis; Chromatography, Thin Layer; Dipeptides; Esters; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Proline; Protein Structure, Secondary; Serine; X-Ray Diffraction | 2002 |
Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Topics: Amino Acid Substitution; Bicarbonates; Binding Sites; Carbon Dioxide; Carbonic Anhydrases; Catalysis; Crystallography, X-Ray; Cysteine; Humans; Mercaptoethanol; Mutagenesis, Site-Directed; Proline; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Thiocyanates; Threonine; Water | 2002 |
Structure of the 1-36 N-terminal fragment of human phospholamban phosphorylated at Ser-16 and Thr-17.
Topics: Arginine; Calcium-Binding Proteins; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphorylation; Proline; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine | 2002 |
Role of protein flexibility in the catalytic cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Substitution; Benzene Derivatives; Catalysis; Flavins; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Proline; Pseudomonas aeruginosa; Recombinant Proteins; Serine | 2002 |
In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Brain; Cell Line; Cloning, Molecular; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neurofilament Proteins; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Serine; Spinal Cord; Time Factors | 2002 |
Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.
Topics: Actins; Amino Acid Motifs; Animals; Binding Sites; Carrier Proteins; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Fibroblasts; Genes, Reporter; Genetic Complementation Test; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Mice; Microfilament Proteins; Nerve Tissue Proteins; Phenotype; Phosphoproteins; Phosphorylation; Proline; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Serine; Threonine; Vinculin; Wiskott-Aldrich Syndrome Protein, Neuronal | 2002 |
Mutational analyses of the signals involved in the subcellular location of DSCR1.
Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Probing Src homology 2 domain ligand interactions by differential line broadening.
Topics: Isoleucine; Leucine; Ligands; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylinositol 3-Kinases; Proline; Protein Subunits; Serine; src Homology Domains; Tyrosine | 2002 |
Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dental Enamel; Dental Enamel Proteins; Hydrolysis; Leucine; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Methionine; Peptide Mapping; Proline; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Serine; Statistics as Topic; Substrate Specificity; Swine; Time Factors; Tooth Calcification; Tryptophan | 2002 |
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.
Topics: Amino Acid Sequence; Amino Acids; Animals; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamic Acid; Humans; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Mutation; Plasmids; Proline; Proteasome Endopeptidase Complex; Protein Folding; Serine; Threonine; Transfection | 2002 |
Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.
Topics: Amino Acid Motifs; Amino Acid Sequence; CD3 Complex; Cells, Cultured; DNA-Binding Proteins; Humans; Interleukin-15; Interleukin-2; Interleukin-7; Interleukin-9; Milk Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides, Antisense; Phorbol Esters; Phosphorylation; Proline; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins A-raf; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Serine; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; T-Lymphocytes; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
Role of dynamic interactions in effective signal transfer for Gbeta stimulation of phospholipase C-beta 2.
Topics: Amino Acid Sequence; Animals; Arginine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Insecta; Isoenzymes; Kinetics; Molecular Sequence Data; Oligonucleotides; Peptide Library; Peptides; Phospholipase C beta; Plasmids; Proline; Protein Binding; Protein Conformation; Serine; Signal Transduction; Spectrometry, Fluorescence; Type C Phospholipases; Valine | 2002 |
Stereoselective synthesis of beta-substituted phenylalanine-beta-phenylisoserine-derived tripeptides using N-cinnamoyl-L-proline as template: synthesis of structural analogues of HIV protease inhibitors.
Topics: Cinnamates; Crystallography, X-Ray; HIV Protease Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Peptides; Phenylalanine; Proline; Serine; Stereoisomerism | 2002 |
Hb Rampa [alpha 95(G2)pro-->Ser (alpha 2)] in a family of European ancestry: DNA analysis confirms the CCG-->TCG mutation at codon 95 of the alpha 2-globin gene; clinical and laboratory features.
Topics: Adult; Aged; Amino Acid Substitution; Child; Codon; Cytosine; DNA Mutational Analysis; Female; Globins; Guanine; Hemoglobins, Abnormal; Humans; Male; Middle Aged; Mutation; Pedigree; Proline; Serine; Thymine | 2002 |
Conserved proline residue at position 189 in cone visual pigments as a determinant of molecular properties different from rhodopsins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Avian Proteins; Cell Line; Chickens; Conserved Sequence; Epitopes; Eye Proteins; Genetic Vectors; Glycine; Humans; Isoleucine; Leucine; Mice; Proline; Retinal Cone Photoreceptor Cells; Retinal Pigments; Rhodopsin; Serine; Spectrophotometry; Thermodynamics; Valine | 2002 |
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation | 2003 |
Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2.
Topics: CDC2 Protein Kinase; G2 Phase; HeLa Cells; Humans; Mitosis; Phosphorylation; Proline; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine | 2003 |
Novel mutant human fibronectin FIII9-10 domain pair with increased conformational stability and biological activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Adhesion; Cells, Cultured; Escherichia coli; Fibronectins; Humans; Leucine; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Proline; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Solubility | 2002 |
Serine-cis-proline and serine-trans-proline isosteres: stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements.
Topics: Alkenes; Catalysis; Chemistry, Organic; Dipeptides; Molecular Mimicry; Molecular Structure; Proline; Serine; Stereoisomerism | 2003 |
Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Antineoplastic Agents; Cells, Cultured; Humans; Immunosuppressive Agents; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Proline; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Sirolimus; Threonine; Transfection; Wortmannin | 2003 |
The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Centrifugation, Density Gradient; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; Crystallography, X-Ray; Cysteine; Disulfides; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Exons; Gene Deletion; Glycine; Heparin; Hot Temperature; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Phenotype; Plasmids; Polymerase Chain Reaction; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serpins; Sucrose; Temperature | 2003 |
Hb St. Luke's [alpha95(G2)Pro --> Arg (alpha1)].
Topics: Arginine; Hemoglobins, Abnormal; Humans; Mutation, Missense; Proline; Serine | 2003 |
Cold-spray ionization mass spectrometry: principle and applications.
Topics: Base Sequence; Cold Temperature; DNA; Ions; Mass Spectrometry; Models, Molecular; Molecular Structure; Nucleosides; Organometallic Compounds; Proline; Serine | 2003 |
Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family.
Topics: Adult; Algeria; Cerebral Cortex; Dementia; DNA Mutational Analysis; Family Health; Female; Humans; Immunohistochemistry; Inclusion Bodies; Jews; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Neuropsychological Tests; Parkinsonian Disorders; Pedigree; Proline; Serine; tau Proteins; Tomography, Emission-Computed, Single-Photon | 2003 |
GPVI levels in platelets: relationship to platelet function at high shear.
Topics: Alleles; Animals; Blood Platelets; Cell Adhesion; Collagen; Crotalid Venoms; Flow Cytometry; Genetic Variation; Genotype; Glycoproteins; Homozygote; Humans; Integrin alpha2beta1; Lectins, C-Type; Mice; Mice, Inbred C57BL; Myeloproliferative Disorders; Platelet Membrane Glycoproteins; Point Mutation; Polymorphism, Genetic; Proline; Serine; Stress, Mechanical; Thrombosis; Transfection; von Willebrand Factor | 2003 |
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
Topics: 2,6-Dichloroindophenol; Alanine; Amino Acids; Ammonia; Gastric Juice; Helicobacter pylori; Humans; In Vitro Techniques; Oxidation-Reduction; Oxygen Consumption; Proline; Pyruvic Acid; Serine; Stereoisomerism | 2003 |
Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.
Topics: Alanine; Amino Acids; Gases; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Peptides; Proline; Protons; Serine; Thermodynamics | 2003 |
Amino acid composition and electrophoretic properties of hypertensin I.
Topics: Amino Acids; Angiotensin Amide; Angiotensins; Arginine; Aspartic Acid; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Proline; Serine; Tyrosine; Valine | 1955 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
O-sulphate esters of L-serine, L-threonine and L-hydroxyproline.
Topics: Amino Acids; Esters; Hydroxyproline; Proline; Serine; Sulfates; Threonine | 1961 |
Amino acid dependent control of DNA synthesis in bacteria and vegetative phage.
Topics: Amino Acids; Arginine; Coliphages; Cysteine; DNA; DNA, Bacterial; Escherichia coli; Histidine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan | 1962 |
GAS CHROMATOGRAPHY OF THE METHYL ESTERS OF THE AMINO ACIDS AS THE FREE BASE AND BY DISSOCIATION OF THEIR ACID SALTS.
Topics: Acetates; Amino Acids; Aspartic Acid; Chlorides; Chromatography; Chromatography, Gas; Cysteine; Cystine; Esters; Hydroxyproline; Ion Exchange Resins; Leucine; Lysine; Phenylalanine; Proline; Research; Salts; Serine | 1963 |
GENE TRANSFER BY F' STRAINS OF ESCHERICHIA COLI K-12. II. INTERACTION BETWEEN F-MEROGENOTE AND CHROMOSOME DURING TRANSFER.
Topics: Chromosomes; Escherichia coli; Escherichia coli K12; Galactose; Histidine; Isoleucine; Lactose; Leucine; Maltose; Mannitol; Methionine; Proline; Research; Serine; Streptomycin; Thiamine; Threonine; Tryptophan; Valine; Xylose | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
AMINO-ACID CONFIGURATION OF MYCOBACILLIN.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Aspartic Acid; Chemistry Techniques, Analytical; Glutamates; Leucine; Mycobacillin; Proline; Research; Serine; Tyrosine | 1963 |
ORIGIN OF PROTOTROPHIC VARIANTS IN MIXTURES OF AUXOTROPHIC MUTANTS OF SERRATIA MARCESCENS.
Topics: Adenine; Isoleucine; Leucine; Massachusetts; Mutation; Proline; Research; Serine; Serratia marcescens; Streptomycin; Thiamine; Tryptophan; Ultraviolet Rays | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
UTILIZATION OF CERTAIN SUBSTRATES BY LARVAL AND ADULT STAGES OF HIMASTHLA QUISSETENSIS.
Topics: Animals; Carbohydrate Metabolism; Glucose; Glutamine; Ketoglutaric Acids; Larva; Malonates; Mannose; Metabolism; Proline; Proteins; Pyruvates; Research; Ribose; Serine; Succinates; Trematoda | 1963 |
GREEN FLUORESCENT PIGMENT ACCUMULATED BY A MUTANT OF CELLVIBRIO GILVUS.
Topics: Amino Acids; Bacteria; Carbon Isotopes; Cellvibrio; Chromatography; Culture Media; Fluorescence; Glucose; Glycine; Levulinic Acids; Lysine; Phenylalanine; Pigments, Biological; Proline; Research; Serine | 1964 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
A DETERMINATION OF THE ESSENTIAL AMINO ACID PROPORTIONS NEEDED TO ALLOW RAPID GROWTH IN CHICKS.
Topics: Amino Acids; Amino Acids, Essential; Animals; Animals, Newborn; Arginine; Caseins; Chickens; Cystine; Diet; Dietary Proteins; Glutamates; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Poultry; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
CHELATION IN HUMAN SWEAT.
Topics: Amino Acids; Chelating Agents; Edetic Acid; Glutamates; Histidine; Imidazoles; Lactates; Magnesium; Nickel; Proline; Research; Serine; Spectrophotometry; Sweat | 1964 |
NITROGEN BALANCES FOR YOUNG ADULT MALES FED TWO SOURCES OF NONESSENTIAL NITROGEN AT TWO LEVELS OF TOTAL NITROGEN INTAKE.
Topics: Alanine; Ammonium Compounds; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Male; Nitrogen; Nitrogen Fixation; Proline; Proteins; Quaternary Ammonium Compounds; Serine | 1964 |
[EFFECTS OF HYDROXYLAMINE ON ESCHERICHIA COLI BIOSYNTHESIS].
Topics: Aspartic Acid; Escherichia coli; Glycine; Hydroxylamine; Hydroxylamines; Lysine; Pharmacology; Phenylalanine; Proline; Proteins; Research; Serine | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
THE ELECTRON MICROSCOPIC LOCALIZATION OF THE NEUTRAL SOLUBLE PROTEINS OF DEVELOPING BOVINE ENAMEL.
Topics: Amino Acids; Animals; Cattle; Dental Calculus; Dental Enamel; Electrons; Embryology; Glutamine; Glycine; Histidine; Histocytochemistry; Microscopy; Microscopy, Electron; Proline; Proteins; Research; Serine | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
AN ANALYSIS OF THE OPTICAL ROTATORY DISPERSION OF POLYPEPTIDES AND PROTEINS.
Topics: Alanine; Animals; Cattle; Chemical Phenomena; Chemistry; Fibrinogen; Globulins; Glutamates; Lysine; Muscle Proteins; Optical Rotatory Dispersion; Peptides; Proline; Proteins; Research; Ribonucleases; Serine; Serum Albumin; Serum Albumin, Bovine | 1964 |
ANABOLIC RESPONSES OF DIAPHRAGM MUSCLE TO INSULIN AND TO OTHER PANCREATIC PROTEINS.
Topics: Carbohydrate Metabolism; Carboxypeptidases; Chymotrypsin; Diaphragm; Endopeptidases; Glucose; Glycogen; Hydrolases; Insulin; Metabolism; Muscle, Smooth; Muscles; Pepsin A; Pharmacology; Proline; Proteins; Rats; Research; Serine; Trypsin; Xylose | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
STUDIES ON THE BIOLOGICAL ACTIVITY OF RIBONUCLEIC ACID ISOLATED FROM ESCHERICHIA COLI AFTER EXPOSURE TO 5-FLUOROURACIL.
Topics: Arginine; Escherichia coli; Fluorouracil; Leucine; Metabolism; Pharmacology; Proline; Proteins; Research; RNA; RNA, Bacterial; Serine; Spectrophotometry | 1964 |
CLUSTERING OF FUNCTIONALLY RELATED GENES IN SALMONELLA TYPHIMURIUM.
Topics: Arginine; Cysteine; Escherichia coli; Glycine; Guanine; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Molecular Biology; Mutation; Pantothenic Acid; Proline; Purines; Pyrimidines; Research; Salmonella typhimurium; Serine; Threonine; Tryptophan | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
RNA CODEWORDS AND PROTEIN SYNTHESIS. THE NUCLEOTIDE SEQUENCES OF MULTIPLE CODEWORDS FOR PHENYLALANINE, SERINE, LEUCINE, AND PROLINE.
Topics: Base Sequence; Carbon Isotopes; Chromatography; Electrophoresis; Escherichia coli; Genetic Code; Leucine; Nucleotides; Phenylalanine; Proline; Protein Biosynthesis; Proteins; Research; Ribosomes; RNA; RNA, Bacterial; Serine | 1965 |
[APPLICATION OF THIN-LAYER CHROMATOGRAPHY TO SEQUENCE ANALYSIS OF PEPTIDES. 3. NONDESTRUCTIVE DETECTION OF AMINO ACIDS ON THE THIN-LAYER CHROMATOGRAM].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chromatography; Chromatography, Thin Layer; Histidine; Peptides; Proline; Research; Sequence Analysis; Serine; Tyrosine; Valine | 1964 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
[Probable reactions in the photosynthesis of glycine, serine and proline in mixtures of paraformaldehyde and potassium nitrate].
Topics: Formaldehyde; Glycine; Nitrates; Photosynthesis; Polymers; Potassium Compounds; Proline; Serine | 1955 |
Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity for mammalian GnRH and chicken GnRH-II.
Topics: Animals; Chickens; DNA Primers; Glutamic Acid; Gonadotropin-Releasing Hormone; Kinetics; Ligands; Mammals; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Conformation; Protein Structure, Secondary; Rats; Receptors, LHRH; Serine; Species Specificity; Substrate Specificity | 2004 |
Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein.
Topics: Adolescent; Carrier Proteins; Chromosomes, Human, X; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Histiocytosis, Non-Langerhans-Cell; Humans; Intracellular Signaling Peptides and Proteins; Male; Mutation; Proline; Serine; Signaling Lymphocytic Activation Molecule Associated Protein | 2003 |
Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.
Topics: alpha-Glucosidases; Amino Acid Sequence; Amino Acids; Asparagine; Bacillus; Binding Sites; Catalysis; Evolution, Molecular; Glycine; Isomaltose; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oligo-1,6-Glucosidase; Phylogeny; Plasmids; Proline; Serine; Substrate Specificity; Threonine; Trehalose | 2003 |
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.
Topics: Adenosine Monophosphate; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome-B(5) Reductase; Flavin-Adenine Dinucleotide; Humans; Kinetics; Methemoglobinemia; Mutagenesis, Site-Directed; NAD; Proline; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.
Topics: Amino Acid Sequence; Blotting, Northern; Cell Line; Conserved Sequence; Cytoplasm; Deoxyribonuclease I; DNA-Binding Proteins; DNA, Complementary; Fatty Acids, Unsaturated; Gene Library; Genes, Reporter; Green Fluorescent Proteins; HeLa Cells; Humans; Huntingtin Protein; Luciferases; Luminescent Proteins; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Localization Signals; Nuclear Proteins; Plasmids; Proline; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Transcription Factors; Transcription, Genetic; Two-Hybrid System Techniques; Zinc Fingers | 2004 |
Solution structure and stability of the full-length excisionase from bacteriophage HK022.
Topics: Amino Acid Motifs; Bacteriophage HK022; Calorimetry, Differential Scanning; Cysteine; DNA; DNA Nucleotidyltransferases; Hydrogen-Ion Concentration; Isoaspartic Acid; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutation; Plasmids; Proline; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Temperature; Thermodynamics; Viral Proteins; Water | 2003 |
Ser and Thr residues modulate the conformation of pro-kinked transmembrane alpha-helices.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Receptors, G-Protein-Coupled; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 2004 |
An atypical topoisomerase II sequence from the slime mold Physarum polycephalum.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Cell Cycle; DNA Topoisomerases, Type II; DNA, Complementary; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Phylogeny; Physarum polycephalum; Proline; Restriction Mapping; RNA, Messenger; Sequence Analysis, DNA; Serine | 2004 |
Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism.
Topics: Adult; Alcoholism; Alleles; Carrier Proteins; Female; Genotype; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotic Disorders; Polymorphism, Genetic; Proline; Psychiatric Status Rating Scales; Receptors, GABA-A; Regression Analysis; Serine; Serotonin Plasma Membrane Transport Proteins; Surveys and Questionnaires | 2004 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Proline versus charge concept for protein stabilization against proteolytic attack.
Topics: Amino Acid Substitution; Animals; Cattle; Lysine; Mutation; Peptide Hydrolases; Proline; Protein Engineering; Protein Structure, Tertiary; Ribonuclease, Pancreatic; Serine | 2003 |
A novel highly pathogenic Alzheimer presenilin-1 mutation in codon 117 (Pro117Ser): Comparison of clinical, neuropathological and cell culture phenotypes of Pro117Leu and Pro117Ser mutations.
Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Codon; Disease Progression; Female; Gene Expression; Genotype; Humans; Male; Membrane Proteins; Mice; Middle Aged; Mutation, Missense; Neurites; Neuroblastoma; Neurofibrillary Tangles; Neurologic Examination; Pedigree; Phenotype; Presenilin-1; Proline; Serine; Transfection; Tumor Cells, Cultured | 2004 |
A twist code determines the onset of osteoblast differentiation.
Topics: Aging; Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Core Binding Factor Alpha 1 Subunit; DNA Mutational Analysis; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Gene Expression Regulation; Heterozygote; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myogenic Regulatory Factors; Neoplasm Proteins; Nuclear Proteins; Osteoblasts; Osteogenesis; Precipitin Tests; Proline; Protein Structure, Tertiary; Rats; Repressor Proteins; RNA; Serine; Skeleton; Staining and Labeling; Transcription Factors; Transcriptional Activation; Transfection; Twist-Related Protein 1 | 2004 |
A new mutation in the hepatocyte nuclear factor-1-alpha gene (P224S) in a newly discovered German family with maturity-onset diabetes of the young 3 (MODY 3). Family members carry additionally the homozygous I27L amino acid polymorphism in the HNF1 alpha
Topics: Adolescent; Aged; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Exons; Female; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Homozygote; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Mutation; Nuclear Proteins; Proline; Serine; Transcription Factors | 2004 |
Functional analysis of two recurrent amino acid substitutions in the CYP21 gene from Italian patients with congenital adrenal hyperplasia.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Amino Acid Substitution; Animals; Child; Child, Preschool; Chlorocebus aethiops; COS Cells; Female; Humans; Infant; Infant, Newborn; Italy; Leucine; Male; Proline; Serine; Steroid 21-Hydroxylase | 2004 |
The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Apoptosis; Arginine; bcl-X Protein; Blotting, Western; Cell Death; Codon; Creatine Kinase; Creatine Kinase, MB Form; Dose-Response Relationship, Drug; Female; Fibroblasts; Flow Cytometry; Genes, p53; Genotype; Homozygote; Humans; Immunoprecipitation; Ischemia; Isoenzymes; Leukocytes; Lymphocytes; Male; Membrane Potentials; Microscopy, Fluorescence; Middle Aged; Myocardial Ischemia; Oxidative Stress; Polymorphism, Genetic; Proline; Proto-Oncogene Proteins c-bcl-2; Regression Analysis; Serine; Time Factors; Transfection; Troponin I; Tumor Suppressor Protein p53 | 2004 |
Hepatitis C virus glycoprotein E2 contains a membrane-proximal heptad repeat sequence that is essential for E1E2 glycoprotein heterodimerization and viral entry.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; COS Cells; Dimerization; Genetic Vectors; Glycoproteins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Transfection; Viral Envelope Proteins | 2004 |
HNPCC mutation MLH1 P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Carrier Proteins; Cell Line, Tumor; Child; Colorectal Neoplasms, Hereditary Nonpolyposis; Female; Genetic Predisposition to Disease; Germ-Line Mutation; HCT116 Cells; Homozygote; Humans; Male; MutL Protein Homolog 1; Neoplasm Proteins; Neurofibromatosis 1; Nuclear Proteins; Proline; Serine | 2004 |
Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture.
Topics: Amino Acids; Animals; Apoptosis; Aspartic Acid; Cell Line; Cell Proliferation; Cells, Immobilized; Dogs; Glucose; Glutamine; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Kinetics; Lactic Acid; Methionine; Proline; Quaternary Ammonium Compounds; Serine; Virus Cultivation; Virus Replication | 2004 |
Photoreceptor degeneration in Pro23His and S334ter transgenic rats.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Apoptosis; Histidine; In Situ Nick-End Labeling; Mutation; Peptide Fragments; Photoreceptor Cells, Vertebrate; Proline; Rats; Retinal Degeneration; Rhodopsin; Serine | 2003 |
Caspase-mediated specific cleavage of human histone deacetylase 4.
Topics: Amino Acid Motifs; Animals; Apoptosis; Aspartic Acid; Binding Sites; Biological Transport; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Dactinomycin; Doxycycline; Genetic Vectors; Glutamic Acid; HeLa Cells; Histone Deacetylases; Humans; Models, Biological; Multienzyme Complexes; Mutagenesis, Site-Directed; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Threonine; Time Factors; Ultraviolet Rays | 2004 |
The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Genetic Vectors; Glutamic Acid; Glutathione Transferase; Hydrogen; Hydrogen Bonding; Hydrolysis; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Point Mutation; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Sodium-Potassium-Exchanging ATPase; Software; Spectrophotometry; Temperature | 2004 |
Congenital methaemoglobinaemia Type I in a Turkish infant due to a novel mutation, Pro144Ser, in NADH-cytochrome b5 reductase.
Topics: Amino Acid Substitution; Ascorbic Acid; Cytochrome-B(5) Reductase; Female; Humans; Infant; Methemoglobinemia; Mutation, Missense; Proline; Serine; Treatment Outcome; Turkey | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Novel CLCN1 mutations in Taiwanese patients with myotonia congenita.
Topics: Adolescent; Adult; Aspartic Acid; Child; Chloride Channels; DNA Mutational Analysis; Female; Glycine; Humans; Isoleucine; Male; Mutation, Missense; Myotonia Congenita; Phenylalanine; Polymorphism, Genetic; Proline; Serine; Taiwan; Threonine | 2004 |
Response to lysine intake in composition of body weight gain and efficiency of lysine utilization of growing male chickens from two genotypes.
Topics: Amino Acids; Animals; Body Composition; Chickens; Cysteine; Energy Metabolism; Genotype; Glycine; Isoleucine; Lipid Metabolism; Lysine; Male; Methionine; Proline; Proteins; Serine; Weight Gain | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2).
Topics: Amino Acid Sequence; Binding Sites; Carbohydrate Conformation; Computer Simulation; Consensus Sequence; Extracellular Space; Glutamic Acid; Glycosylation; Humans; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Peptide Fragments; Polymorphism, Genetic; Proline; Protein Binding; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Symporters | 2004 |
Actin mutations are one cause of congenital fibre type disproportion.
Topics: Actins; Adenosine Triphosphatases; Aspartic Acid; Biopsy; Child, Preschool; DNA Mutational Analysis; Female; Heterozygote; Humans; Infant; Infant, Newborn; Leucine; Male; Models, Molecular; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Mutation, Missense; Myopathies, Structural, Congenital; Proline; Sequence Analysis, Protein; Serine; Valine | 2004 |
Palmitoylation of inducible nitric-oxide synthase at Cys-3 is required for proper intracellular traffic and nitric oxide synthesis.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antifungal Agents; Biological Transport; Boron Compounds; Brefeldin A; Cell Line; Cells, Cultured; Cloning, Molecular; COS Cells; Cysteine; Escherichia coli; Fluorescent Dyes; Golgi Apparatus; Green Fluorescent Proteins; Hydroxylamine; Lysine; Mice; Molecular Sequence Data; Monensin; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Palmitic Acid; Proline; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Time Factors; Transfection | 2004 |
Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Cell Line, Tumor; Disease Models, Animal; DNA Primers; DNA-Binding Proteins; Genetic Markers; Genetic Predisposition to Disease; Genetic Variation; Immunity, Innate; Lymphoma; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Polymorphism, Single Nucleotide; Proline; Serine; Thymus Neoplasms; Transcription Factor MTF-1; Transcription Factors; Transfection | 2005 |
Mapping the functional domains of the Golgi stacking factor GRASP65.
Topics: Binding Sites; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cytosol; Dimerization; Glutathione Transferase; Golgi Apparatus; Golgi Matrix Proteins; Green Fluorescent Proteins; HeLa Cells; Humans; Membrane Proteins; Mitosis; Phosphorylation; Polo-Like Kinase 1; Proline; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Serine | 2005 |
The Smad3 linker region contains a transcriptional activation domain.
Topics: Adenovirus E1A Proteins; Animals; Binding Sites; Cells, Cultured; DNA; DNA-Binding Proteins; Genes, Reporter; Humans; Mammals; Nuclear Proteins; Proline; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Smad3 Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation; Transfection; Transforming Growth Factor beta | 2005 |
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
Topics: Actins; Anaphase-Promoting Complex-Cyclosome; Antibodies, Monoclonal; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine; Lysine; Models, Molecular; Mutation; Mutation, Missense; Neoplasms; Peptides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Time Factors; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2005 |
Determination of the post-translational modifications of salivary acidic proline-rich proteins.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Molecular Weight; Peptides; Phosphorylation; Proline; Protein Isoforms; Protein Processing, Post-Translational; Pyrrolidonecarboxylic Acid; Salivary Proteins and Peptides; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2003 |
In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1.
Topics: Amino Acid Substitution; Computational Biology; Computer Simulation; Cysteine; Humans; Hydrogen Bonding; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Proteins; Proline; Protein Conformation; Protein Structure, Secondary; Serine; Thermodynamics; Tumor Suppressor Protein p53 | 2005 |
Phosphorylation effects on cis/trans isomerization and the backbone conformation of serine-proline motifs: accelerated molecular dynamics analysis.
Topics: Amino Acid Motifs; Isomerism; Models, Chemical; Models, Molecular; Phosphorylation; Proline; Protein Conformation; Serine; Thermodynamics | 2005 |
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Aromatic; Animals; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Lineage; Chickens; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Evolution, Molecular; Gene Library; Gene Silencing; Glutamine; Glycine; HeLa Cells; Humans; In Situ Hybridization; Inhibitory Concentration 50; Intestine, Small; Kidney; Kinetics; Levodopa; Mice; Molecular Sequence Data; Open Reading Frames; Pan troglodytes; Phylogeny; Proline; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Transfection | 2005 |
The alpha-helical propensity of the cytoplasmic domain of phospholamban: a molecular dynamics simulation of the effect of phosphorylation and mutation.
Topics: Algorithms; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Circular Dichroism; Computer Simulation; Cysteine; Cytoplasm; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Myocardium; Peptides; Phosphorylation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sarcoplasmic Reticulum; Serine; Temperature | 2005 |
Association analysis of NAD(P)Hratioquinone oxidoreductase (NQO1) Pro187Ser genetic polymorphism and tardive dyskinesia in patients with schizophrenia in Taiwan.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; DNA Mutational Analysis; Dyskinesias; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Polymorphism, Genetic; Proline; Schizophrenia; Serine; Taiwan | 2005 |
Absence of Pro475Ser polymorphism in ADAMTS-13 in Caucasians.
Topics: ADAM Proteins; ADAMTS13 Protein; Alleles; Case-Control Studies; Female; Genotype; Humans; Male; Metalloendopeptidases; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Risk; Risk Factors; Serine; White People | 2005 |
Natural mutations in a 2'-5' oligoadenylate synthetase transgene revealed residues essential for enzyme activity.
Topics: 2',5'-Oligoadenylate Synthetase; Amino Acid Sequence; Animals; Enzyme Activation; Glycine; Humans; Isoenzymes; Lysine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Serine; Transgenes | 2005 |
Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites.
Topics: Animals; Asparagine; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; Consensus Sequence; COS Cells; Cytoplasm; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Tumor Necrosis Factor, Type I; Sequence Deletion; Serine; Tumor Necrosis Factor-alpha | 2005 |
Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Biotinylation; Catalysis; Catalytic Domain; Cell Membrane; Computer Simulation; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Glycine; Haplorhini; Humans; Immunoblotting; Immunoprecipitation; Matrix Metalloproteinase 16; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Point Mutation; Proline; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Time Factors; Transfection; Vaccinia virus | 2005 |
Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage.
Topics: Animals; Cell Line; Cell Line, Tumor; Checkpoint Kinase 2; DNA Damage; Embryo, Mammalian; Fibroblasts; Gene Deletion; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Osteosarcoma; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Protein Serine-Threonine Kinases; Serine; Tumor Suppressor Protein p53 | 2005 |
Relating kinetic rates and local energetic roughness by accelerated molecular-dynamics simulations.
Topics: Algorithms; Amino Acid Motifs; Biopolymers; Computer Simulation; Diffusion; Isomerism; Kinetics; Proline; Protein Conformation; Protein Folding; Serine; Thermodynamics | 2005 |
Synthesis and secondary structure of loop 4 of myelin proteolipid protein: effect of a point mutation found in Pelizaeus-Merzbacher disease.
Topics: Amino Acid Sequence; Amino Acid Substitution; Circular Dichroism; Dimethyl Sulfoxide; Humans; Iodine; Micelles; Molecular Sequence Data; Myelin Proteolipid Protein; Oxidation-Reduction; Pelizaeus-Merzbacher Disease; Peptide Fragments; Peptides; Point Mutation; Proline; Protein Structure, Secondary; Serine; Sodium Dodecyl Sulfate; Trifluoroethanol | 2005 |
Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
Topics: Alanine; Alzheimer Disease; Arginine; Binding Sites; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Disulfides; DNA Mutational Analysis; Dose-Response Relationship, Drug; Factor XIa; Humans; Inhibitory Concentration 50; Kinetics; Lysine; Models, Molecular; Models, Statistical; Mutation; Partial Thromboplastin Time; Phenylalanine; Plasmids; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Thromboplastin; Time Factors; Vesicular Transport Proteins | 2005 |
Four novel connexin 32 mutations in X-linked Charcot-Marie-Tooth disease with phenotypic variability.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Charcot-Marie-Tooth Disease; Chromosomes, Human, X; Codon, Terminator; Connexins; DNA Mutational Analysis; Family Health; Female; Gap Junction beta-1 Protein; Humans; Leucine; Male; Middle Aged; Mutation; Phenotype; Phenylalanine; Proline; Serine; Tyrosine; Valine | 2006 |
Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology.
Topics: Amino Acid Substitution; Animals; Autoantibodies; B-Lymphocytes; Encephalomyelitis, Autoimmune, Experimental; Glycosylation; Humans; Immunization; Immunodominant Epitopes; Immunoglobulin G; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin Sheath; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Oligodendroglia; Proline; Rats; Serine | 2005 |
Phosphorylation of human DNA polymerase lambda by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen.
Topics: Amino Acid Sequence; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; DNA Polymerase beta; HeLa Cells; Humans; Molecular Sequence Data; Phosphorylation; Proliferating Cell Nuclear Antigen; Proline; Protein Structure, Tertiary; Serine | 2005 |
Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in japanese depressed patients.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Chi-Square Distribution; Cytochrome P-450 CYP2D6; Depression; Female; Fluvoxamine; Humans; Japan; Male; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Proline; Receptor, Serotonin, 5-HT2A; Serine; Tyrosine | 2006 |
Mutations in mtDNA-encoded cytochrome c oxidase subunit genes causing isolated myopathy or severe encephalomyopathy.
Topics: Adult; DNA Mutational Analysis; Electron Transport Complex IV; Glutamic Acid; Humans; Immunohistochemistry; Male; Mitochondrial Encephalomyopathies; Muscle, Skeletal; Muscular Diseases; Mutation; Proline; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyolysis; RNA, Messenger; Serine | 2005 |
Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients.
Topics: Arginine; Body Mass Index; Breast Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Linkage Disequilibrium; Middle Aged; Polymorphism, Genetic; Proline; Proportional Hazards Models; Radiodermatitis; Radiotherapy; Retrospective Studies; Serine; Tumor Suppressor Protein p53 | 2006 |
Familial autosomal dominant cortico-basal degeneration with the P301S mutation in the tau gene: an example of phenotype variability.
Topics: Adult; Basal Ganglia; Cerebral Cortex; DNA Mutational Analysis; Family Health; Humans; Machado-Joseph Disease; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Pedigree; Phenotype; Proline; Serine; tau Proteins; Tomography, Emission-Computed, Single-Photon | 2005 |
Characterization of the theta-type plasmid pCD3.4 from Carnobacterium divergens, and modulation of its host range by RepA mutation.
Topics: Bacterial Proteins; Bacteriocin Plasmids; Base Sequence; DNA Helicases; DNA Replication; DNA-Binding Proteins; Gram-Positive Bacteria; Molecular Sequence Data; Mutation; Proline; Serine; Trans-Activators | 2006 |
Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65.
Topics: Amino Acid Motifs; DNA-Binding Proteins; HeLa Cells; Humans; In Vitro Techniques; Nuclear Proteins; Phosphorylation; Proline; Protein Binding; Ribonucleoproteins; RNA; RNA Splicing Factors; Serine; Splicing Factor U2AF; Transcription Factors | 2006 |
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Casein Kinase II; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Chromatin; Chromatography, Liquid; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; DNA Helicases; Electrophoresis, Polyacrylamide Gel; Fibroblasts; HeLa Cells; Humans; Ions; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Minichromosome Maintenance Complex Component 2; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphorylation; Proline; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Phase Kinase-Associated Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine; Transfection; Trypsin | 2006 |
A biomimetic chromanol cyclization leading to alpha-tocopherol.
Topics: alpha-Tocopherol; Aspartic Acid; Biomimetics; Chromans; Cyclization; Indicators and Reagents; Proline; Serine; Stereoisomerism | 2006 |
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2006 |
A new mutation in PRKAG2 gene causing hypertrophic cardiomyopathy with conduction system disease and muscular glycogenosis.
Topics: Adult; AMP-Activated Protein Kinases; Cardiomyopathy, Hypertrophic; DNA Mutational Analysis; Exercise; Glycogen Storage Disease; Heart Conduction System; Humans; Male; Multienzyme Complexes; Muscle, Skeletal; Mutation; Proline; Protein Serine-Threonine Kinases; Serine | 2006 |
Molecular characterization of serine-, alanine-, and proline-rich proteins of Trypanosoma cruzi and their possible role in host cell infection.
Topics: Alanine; Amino Acid Sequence; Animals; Calcium; Cell Adhesion Molecules; Genome, Protozoan; HeLa Cells; Humans; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Protozoan Proteins; Serine; Trypanosoma cruzi | 2006 |
A case of patient affected by hirsutism carrying the P482S CYP21 gene mutation associated with loss of heterozygosity (LOH).
Topics: Adult; Female; Heterozygote; Hirsutism; Humans; Loss of Heterozygosity; Mutation; Proline; Serine; Steroid 21-Hydroxylase | 2006 |
Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.
Topics: Alanine; Computer Simulation; Glycine; Models, Chemical; Proline; Quantum Theory; Serine; Solutions; Time Factors | 2006 |
Characterization of recombinant Xenopus laevis type I iodothyronine deiodinase: substitution of a proline residue in the catalytic center by serine (Pro132Ser) restores sensitivity to 6-propyl-2-thiouracil.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; Iodide Peroxidase; Kinetics; Molecular Sequence Data; Mutation; Proline; Propylthiouracil; Rats; Selenocysteine; Sequence Homology, Amino Acid; Serine; Xenopus laevis | 2006 |
Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apoenzymes; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Glycine; Lacticaseibacillus casei; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Synthases; Proline; Protein Structure, Secondary; Sequence Alignment; Serine | 2006 |
Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.
Topics: Animals; Cells, Cultured; DEAD Box Protein 58; DEAD-box RNA Helicases; Down-Regulation; Immunity, Innate; Interferon Regulatory Factor-3; Interferon-beta; Mice; Mice, Inbred Strains; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Proteasome Endopeptidase Complex; RNA Helicases; RNA Interference; RNA Virus Infections; RNA Viruses; RNA, Double-Stranded; Serine; Toll-Like Receptor 3; Transcriptional Activation; Ubiquitin | 2006 |
Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models.
Topics: Acetamides; Algorithms; Binding Sites; Catalysis; Hydrogen Bonding; Isomerism; Models, Chemical; Nitrogen; Oxygen; Peptides; Peptidylprolyl Isomerase; Proline; Protons; Pyrrolidines; Serine; Thermodynamics; Threonine | 2006 |
Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Binding Sites, Antibody; CHO Cells; Cricetinae; Down Syndrome; Dyrk Kinases; Electrophysiology; Endocytosis; Hippocampus; Humans; Mice; Nerve Tissue Proteins; NIH 3T3 Cells; Organ Culture Techniques; Phosphorylation; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Recombinant Fusion Proteins; Serine | 2006 |
Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding.
Topics: Animals; Antigens, CD; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Dimerization; Down-Regulation; Humans; Immunoglobulin G; Ligands; Methotrexate; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Proline; Receptors, IgG; Serine; Signal Transduction; Tetrahydrofolate Dehydrogenase | 2006 |
Clinical features of hereditary spastic paraplegia due to spastin mutation.
Topics: Adenosine Triphosphatases; Adult; Aged; Cohort Studies; DNA Mutational Analysis; Exons; Female; Genetic Testing; Glutamine; Humans; Leucine; Male; Middle Aged; Mutation; Phenotype; Proline; Retrospective Studies; Serine; Spastic Paraplegia, Hereditary; Spastin; United Kingdom | 2006 |
Characterization of proline-serine-rich carboxyl terminus in human sulfotransferase 2B1b: immunogenicity, subcellular localization, kinetic properties, and phosphorylation.
Topics: Cell Line, Tumor; Dehydroepiandrosterone; Electrophoresis, Gel, Two-Dimensional; Enzyme Stability; Humans; Immunoblotting; Intracellular Space; Isoenzymes; Kinetics; Mass Spectrometry; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Serine; Sulfates; Sulfotransferases; Temperature; Transfection | 2006 |
Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8).
Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Cell Line, Tumor; Endoplasmic Reticulum; Genetic Linkage; Genetic Predisposition to Disease; Humans; Mice; Proline; Protein Folding; Serine; Solubility; Vesicular Transport Proteins | 2006 |
Specific cleavage of DJ-1 under an oxidative condition.
Topics: Blotting, Western; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Gene Expression; Glycine; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Neuroblastoma; Oncogene Proteins; Oxidants; Oxidation-Reduction; Oxidative Stress; Proline; Protein Deglycase DJ-1; Serine | 2006 |
Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia.
Topics: Adult; Autonomic Nervous System Diseases; Brazil; Electromyography; Female; Humans; Male; Middle Aged; Muscular Atrophy, Spinal; Mutation; Pedigree; Phenotype; Proline; Serine; Vesicular Transport Proteins | 2006 |
Exploring the role of the active site cysteine in human muscle creatine kinase.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Computer Simulation; Creatine; Creatine Kinase, MM Form; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutant Proteins; Phosphorylation; Proline; Serine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Torpedo | 2006 |
The homozygous P582S mutation in the oxygen-dependent degradation domain of HIF-1 alpha is associated with increased risk for prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Cell Hypoxia; Female; Gene Frequency; Genetic Predisposition to Disease; Homozygote; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jews; Male; Middle Aged; Oxygen; Point Mutation; Proline; Prostatic Neoplasms; Protein Structure, Tertiary; Risk Factors; Serine | 2007 |
A structural model of the SHBG domain of human variant protein S Heerlen.
Topics: Binding Sites; Complement C4b-Binding Protein; Computer Simulation; Humans; Models, Molecular; Mutation; Proline; Protein S; Protein Structure, Tertiary; Serine; Sex Hormone-Binding Globulin | 2006 |
Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome.
Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Calpain; Electrophoresis, Polyacrylamide Gel; Glutamates; Hydrolysis; Models, Biological; Molecular Sequence Data; Mutation; Proline; Proteasome Endopeptidase Complex; Serine; Substrate Specificity; Swine; Threonine | 2006 |
Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Base Sequence; Cells, Cultured; Conserved Sequence; DNA Primers; Interleukin-6; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oncostatin M; Phosphorylation; Proline; Recombinant Proteins; Serine; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Transfection | 2006 |
A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.
Topics: Adenocarcinoma, Mucinous; Adenoma; Adult; Brain Neoplasms; Carcinoma; Cholangiocarcinoma; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Mutational Analysis; DNA Probes; DNA-Binding Proteins; Endometrial Neoplasms; Female; Germ-Line Mutation; Humans; Liver Neoplasms; Microsatellite Instability; Mutation, Missense; MutS Homolog 2 Protein; Neoplasms, Multiple Primary; Neoplastic Syndromes, Hereditary; Polyps; Proline; Sebaceous Gland Neoplasms; Serine; Skin Neoplasms; Syndrome | 2007 |
Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Carcinoma, Squamous Cell; Codon; Cyclin-Dependent Kinase Inhibitor p21; Female; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Proline; Risk Factors; Serine; Smoking; Tumor Suppressor Protein p53 | 2007 |
Two new missense mutations of GAA in late onset glycogen storage disease type II.
Topics: Adult; alpha-Glucosidases; Child; DNA Mutational Analysis; Family Health; Female; Glycogen Storage Disease Type II; Humans; Korea; Lysine; Male; Methionine; Middle Aged; Mutation, Missense; Proline; Serine | 2006 |
Identification of novel FZD4 mutations in Indian patients with familial exudative vitreoretinopathy.
Topics: Adolescent; Adult; Amino Acid Sequence; Arginine; Asian People; Cysteine; Exons; Exudates and Transudates; Eye Diseases; Fluorescein Angiography; Frizzled Receptors; Fundus Oculi; Humans; India; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Phenylalanine; Proline; Receptors, G-Protein-Coupled; Retinal Diseases; Serine; Vitreous Body | 2006 |
Cloning and characterization of scale beta-keratins in the differentiating epidermis of geckoes show they are glycine-proline-serine-rich proteins with a central motif homologous to avian beta-keratins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; beta-Keratins; Blotting, Northern; Blotting, Southern; Cloning, Molecular; DNA, Complementary; Epidermis; Gene Expression; Glycine; Immunohistochemistry; In Situ Hybridization; Lizards; Molecular Sequence Data; Oligonucleotides; Proline; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology; Serine | 2007 |
Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Mutagenesis, Site-Directed; N-Methylscopolamine; Proline; Protein Conformation; Receptors, Muscarinic; Serine; Strychnine; Threonine; Valine | 2006 |
Essential role of proline isomerization in stefin B tetramer formation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Circular Dichroism; Cross-Linking Reagents; Crystallography, X-Ray; Cystatin B; Cystatins; Dimerization; Genetic Variation; Glutaral; Humans; Hydrogen-Ion Concentration; Isomerism; Light; Models, Chemical; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Scattering, Radiation; Sequence Homology, Amino Acid; Serine; Solutions; Trifluoroethanol | 2007 |
The role of the amino acid residue at alpha1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors.
Topics: Acetylcholine; Animals; Bungarotoxins; Cell Line; Cholinergic Agents; Humans; Mice; Muscles; Mutation; Neuromuscular Blocking Agents; Oocytes; Phenylalanine; Proline; Receptors, Nicotinic; Serine; Vecuronium Bromide; Xenopus | 2007 |
Involvement of loops L2 and L4 of ribonucleolytic toxin restrictocin in its functional activity.
Topics: Amino Acid Substitution; Circular Dichroism; Fungal Proteins; HeLa Cells; Humans; Lysine; Mutagenesis, Site-Directed; Mutation; Mycotoxins; Proline; Protein Synthesis Inhibitors; Recombinant Proteins; Ribonucleases; RNA; RNA, Ribosomal, 28S; Serine; Structure-Activity Relationship; Substrate Specificity | 2007 |
Double mutant P96S/S120G of Nm23-H1 abrogates its NDPK activity and motility-suppressive ability.
Topics: Amino Acid Substitution; Cell Movement; Glycine; Humans; Mutation; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Proline; Recombinant Proteins; Serine; Tumor Cells, Cultured | 2007 |
Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function.
Topics: Animals; Brain; Carrier Proteins; Cytoplasmic Structures; Epitopes; Evoked Potentials; Hippocampus; Humans; Membrane Proteins; Mice; Mice, Knockout; Neurons; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Receptors, Glycine; Recombinant Proteins; Serine | 2007 |
Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cells, Cultured; Drosophila melanogaster; Glycine; Glycosylation; Golgi Apparatus; Molecular Sequence Data; Mucins; Mutagenesis, Site-Directed; Pentosyltransferases; Proline; Proteoglycans; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Syndecans; UDP Xylose-Protein Xylosyltransferase | 2007 |
Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis.
Topics: Amino Acid Motifs; Animals; bcl-X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Hepatitis B; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Nude; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Proto-Oncogene Proteins c-myc; Reproducibility of Results; RNA, Messenger; Serine; Trans-Activators; Transcription Factor RelA; Transcription, Genetic; Transcriptional Activation; Transfection; Transplantation, Heterologous; Up-Regulation; Viral Regulatory and Accessory Proteins | 2007 |
A single amino acid in the second transmembrane domain of GABA rho receptors regulates channel conductance.
Topics: Amino Acid Substitution; Amino Acids; Animals; Bass; Cell Line; Cell Membrane; Cells, Cultured; Humans; Ion Channel Gating; Ion Channels; Mutation; Proline; Protein Structure, Tertiary; Receptors, GABA; Receptors, GABA-B; Retinal Bipolar Cells; Sequence Homology, Amino Acid; Serine; Synaptic Transmission | 2007 |
Myocilin mutations among primary open angle glaucoma patients of Kanyakumari district, South India.
Topics: Aged; Asian People; Base Sequence; Cytoskeletal Proteins; Eye Proteins; Female; Glaucoma, Open-Angle; Glycoproteins; Humans; India; Leucine; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Proline; Serine; Threonine; Tyrosine | 2007 |
N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.
Topics: Animals; Cell Cycle Proteins; Chromatin; Chromatin Assembly and Disassembly; Cloning, Molecular; DNA; Dogs; Guanine Nucleotide Exchange Factors; HeLa Cells; Histones; Humans; Kinetics; Luminescent Proteins; Methionine; Methylation; Mitosis; Mutation; Nuclear Proteins; Proline; Protein Binding; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; ran GTP-Binding Protein; Recombinant Fusion Proteins; Serine | 2007 |
The epidermis of scales in gecko lizards contains multiple forms of beta-keratins including basic glycine-proline-serine-rich proteins.
Topics: Amino Acid Sequence; Animals; beta-Keratins; Electrophoresis, Gel, Two-Dimensional; Epidermis; Foot; Glycine; Lizards; Molecular Sequence Data; Proline; Protein Conformation; Protein Isoforms; Serine | 2007 |
Multiple fungal enzymes possess cysteine synthase activity in vitro.
Topics: Arginine; Aspergillus nidulans; Blotting, Northern; Carbon-Oxygen Lyases; Catalysis; Cysteine; Cysteine Synthase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histidine; Models, Biological; Mutation; Phylogeny; Proline; Serine; Sulfates | 2007 |
The first case of Hb Groene Hart [alpha119(H2)Pro-->Ser, CCT-->TCT (alpha1)] homozygosity confirms that a thalassemia phenotype is associated with this abnormal hemoglobin variant.
Topics: Amino Acid Substitution; Genetic Variation; Hemoglobins, Abnormal; Homozygote; Humans; Netherlands; Phenotype; Polymorphism, Single Nucleotide; Proline; Serine; Thalassemia | 2007 |
Effect of selected Ser/Ala and Xaa/Pro mutations on the stability and catalytic properties of a cold adapted subtilisin-like serine proteinase.
Topics: Alanine; Amino Acids; Catalysis; Cold Temperature; Enzyme Stability; Kinetics; Models, Molecular; Mutation; Proline; Protein Structure, Tertiary; Serine; Subtilisin; Temperature; Vibrio | 2007 |
Functional characterization of a novel CFTR mutation P67S identified in a patient with atypical cystic fibrosis.
Topics: Action Potentials; Adolescent; Amino Acid Substitution; Base Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Molecular Sequence Data; Proline; Serine | 2007 |
A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins.
Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Cloning, Molecular; Escherichia coli; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Humans; Mutation; Proline; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Serine; Tubulin; Vesicular Transport Proteins | 2007 |
Hb Evora [alpha 2-35, Ser-->Pro], a novel hemoglobin variant associated with an alpha-thalassemia phenotype.
Topics: alpha-Thalassemia; Female; Genetic Variation; Hemoglobins, Abnormal; Humans; Infant, Newborn; Male; Phenotype; Proline; Serine | 2007 |
Beta-keratins of differentiating epidermis of snake comprise glycine-proline-serine-rich proteins with an avian-like gene organization.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Keratins; Birds; Cell Differentiation; Colubridae; Epidermal Cells; Epidermis; Glycine; Molecular Sequence Data; Proline; Serine | 2007 |
Comparison of L-monosodium glutamate and L-amino acid taste in rats.
Topics: Amino Acids; Animals; Arginine; Avoidance Learning; Dose-Response Relationship, Drug; Glycine; Isomerism; Male; Perception; Proline; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Sodium Glutamate; Taste; Taste Buds; Taste Threshold; Visceral Afferents | 2007 |
A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspergillus fumigatus; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Glucosyltransferases; Molecular Sequence Data; Proline; Sequence Homology, Amino Acid; Serine | 2007 |
Structure and evolution of RIM-BP genes: identification of a novel family member.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Arginine; Brain; Carrier Proteins; Cloning, Molecular; Cytoskeletal Proteins; DNA, Complementary; Evolution, Molecular; Exons; Gene Expression; Humans; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Introns; Male; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Phylogeny; Polymerase Chain Reaction; Proline; Protein Isoforms; Protein Structure, Tertiary; Rats; Rats, Wistar; RNA, Messenger; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Serine | 2007 |
Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin-proteasome system and induces endoplasmic reticulum stress.
Topics: Animals; Aspartic Acid; Caspases; Cell Death; CHO Cells; Cricetinae; Cricetulus; Endoplasmic Reticulum; Glycine; Green Fluorescent Proteins; Humans; Immunoprecipitation; Mutation; Proline; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Processing, Post-Translational; Serine; Stress, Physiological; Time Factors; Transfection; Ubiquitin | 2007 |
Auditory nerve is affected in one of two different point mutations of the neurofilament light gene.
Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Charcot-Marie-Tooth Disease; Evoked Potentials, Auditory, Brain Stem; Family Health; Female; Functional Laterality; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Neurofilament Proteins; Point Mutation; Proline; Reaction Time; Serine; Vestibulocochlear Nerve | 2008 |
Sensing the chirality of Dawson lanthanide polyoxometalates [alpha1-LnP2W17O61]7- by multinuclear NMR spectroscopy.
Topics: Dimerization; Lanthanoid Series Elements; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Organophosphorus Compounds; Oxygen; Proline; Serine; Stereoisomerism; Tungsten | 2008 |
Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma.
Topics: Apoptosis; Arginine; Cyclin-Dependent Kinase Inhibitor p21; DNA Repair; DNA-Binding Proteins; Female; Genes, p53; Humans; Male; Nuclear Proteins; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Serine; Skin Neoplasms; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2008 |
Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy.
Topics: Aged; Asparagine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Italy; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2008 |
Role of Ser-340 and Thr-341 in transmembrane domain IX of the Na+/proline transporter PutP of Escherichia coli in ligand binding and transport.
Topics: Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Biological Transport, Active; Catalysis; Escherichia coli; Escherichia coli Proteins; Eukaryotic Cells; Ligands; Lithium; Models, Biological; Proline; Protein Binding; Protein Structure, Tertiary; Serine; Sodium; Symporters; Tryptophan | 2008 |
The nucleoid binding protein H-NS acts as an anti-channeling factor to favor intermolecular Tn10 transposition and dissemination.
Topics: Bacterial Proteins; DNA Transposable Elements; DNA-Binding Proteins; DNA, Bacterial; DNA, Superhelical; Electrophoresis, Gel, Two-Dimensional; Integration Host Factors; Mutant Proteins; Nucleic Acid Conformation; Plasmids; Proline; Serine | 2008 |
Mouse strain-specific coding polymorphism in the Slc4a2/Ae2 gene encodes Ae2c2 variants differing in isoform-specific dominant negative activity.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Anion Transport Proteins; Antiporters; Base Sequence; Cell Line; Cell Membrane; Chloride-Bicarbonate Antiporters; Chlorides; Genes, Dominant; Genotype; Humans; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Oocytes; Phenotype; Polymorphism, Genetic; Proline; Promoter Regions, Genetic; Protein Isoforms; Recombinant Fusion Proteins; Serine; SLC4A Proteins; Species Specificity; Transfection; Xenopus laevis | 2008 |
The mouse and human Ah receptor differ in recognition of LXXLL motifs.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids, Acidic; Animals; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; DNA-Binding Proteins; Glutamine; Humans; Mice; Molecular Sequence Data; Proline; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation | 2008 |
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders.
Topics: Aged; Asparagine; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Leucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Risk Factors; Serine | 2008 |
Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells.
Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Apoptosis; Cataract; Epithelial Cells; Humans; Lens, Crystalline; Molecular Weight; Mutant Proteins; Mutation; Proline; Protein Structure, Quaternary; Protein Subunits; Protein Transport; Recombinant Proteins; Serine; Subcellular Fractions; Temperature | 2008 |
Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians.
Topics: Adult; Asparagine; Brazil; Female; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2009 |
The mutation p.Ser298Pro in the sulphamidase gene (SGSH) is associated with a slowly progressive clinical phenotype in mucopolysaccharidosis type IIIA (Sanfilippo A syndrome).
Topics: Adolescent; Adult; Child; Child, Preschool; Disease Progression; Female; Genotype; Humans; Hydrolases; Infant; Infant, Newborn; Male; Mucopolysaccharidosis III; Mutation; Phenotype; Proline; Serine | 2008 |
Ser80Ile mutation and a concurrent Pro25Leu variant of the VHL gene in an extended Hungarian von Hippel-Lindau family.
Topics: Amino Acid Sequence; Female; Humans; Male; Mutation; Pedigree; Proline; Protein Structure, Secondary; Sequence Alignment; Serine; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein | 2008 |
One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide.
Topics: Amino Acid Sequence; Animals; CD4 Antigens; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Immunoglobulin G; Immunosuppression Therapy; Injections, Intravenous; Insulin; Mice; Mice, Inbred NOD; Peptide Fragments; Proline; Serine; T-Lymphocytes, Regulatory; Th1 Cells | 2008 |
Phytic acid increases mucin and endogenous amino acid losses from the gastrointestinal tract of chickens.
Topics: Amino Acids; Animal Feed; Animals; Biomarkers; Chickens; Digestion; Feces; Gastrointestinal Tract; Male; Mucins; N-Acetylneuraminic Acid; Phytic Acid; Proline; Random Allocation; Serine; Threonine | 2009 |
A novel PRNP-P105S mutation associated with atypical prion disease and a rare PrPSc conformation.
Topics: Adult; Amino Acid Substitution; Brain; Family Health; Female; Gerstmann-Straussler-Scheinker Disease; Humans; Male; Middle Aged; Mutation; Prion Diseases; Prion Proteins; Prions; Proline; Protein Conformation; PrPSc Proteins; Serine | 2008 |
Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Axons; Conserved Sequence; Gene Knock-In Techniques; Lysine; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Myelin Sheath; Nerve Crush; Neural Pathways; Neurofilament Proteins; Phosphorylation; Proline; Repetitive Sequences, Amino Acid; Serine | 2009 |
Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Binding Sites; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Glycine; Glyphosate; Isoleucine; Kinetics; Models, Chemical; Molecular Conformation; Mutation; Proline; Serine; Threonine | 2009 |
The neurofilament light chain gene (NEFL) mutation Pro22Ser can be associated with mixed axonal and demyelinating neuropathy.
Topics: Adolescent; Amino Acid Sequence; Amino Acid Substitution; Axons; Charcot-Marie-Tooth Disease; Demyelinating Diseases; DNA Mutational Analysis; Electrodiagnosis; Genetic Markers; Genetic Predisposition to Disease; Genotype; Humans; Male; Mutation; Mutation, Missense; Neural Conduction; Neurofilament Proteins; Peripheral Nerves; Phenotype; Proline; Serine | 2009 |
Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Animals; Brain Mapping; Disease Models, Animal; Glycine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Pathways; Proline; Septum of Brain; Serine; Stilbamidines; tau Proteins; Valine | 2009 |
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.
Topics: Analysis of Variance; Animals; Axons; Bacterial Proteins; Disease Models, Animal; Humans; Inclusion Bodies; Intercellular Signaling Peptides and Proteins; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; Nerve Tissue Proteins; Neurofilament Proteins; Ophthalmoscopy; Organ Culture Techniques; Phosphorylation; Proline; Retinal Ganglion Cells; Serine; tau Proteins; Tauopathies | 2011 |
Organocatalytic syn-aldol reactions of dioxanones with (S)-isoserinal hydrate: synthesis of L-deoxymannojirimycin and L-deoxyidonojirimycin.
Topics: 1-Deoxynojirimycin; Aldehydes; Amines; Antiviral Agents; Catalysis; Cyclization; Dioxanes; Enzyme Inhibitors; Proline; Serine | 2009 |
Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Escherichia coli; Escherichia coli Proteins; Glutathione Transferase; Half-Life; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Okadaic Acid; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Recombinant Proteins; Serine; Sulfotransferases; Threonine; Transfection; Two-Hybrid System Techniques | 2009 |
NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristics of human mammary tumors.
Topics: Breast Neoplasms; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Polymorphism, Single Nucleotide; Proline; RNA, Messenger; Serine | 2009 |
Hb Nile[A1] and Hb Nile[A2]: novel identical [alpha77(EF6)Pro-->Ser] variants found in either the alpha1- or alpha2-globin genes.
Topics: alpha-Globins; Anemia; Child; Chromatography, High Pressure Liquid; Codon; Electrophoresis, Capillary; Female; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Male; Mutation, Missense; Pregnancy; Proline; Serine; Young Adult | 2009 |
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia.
Topics: Aged; Alleles; Animals; Cohort Studies; Humans; Hyponatremia; Male; Mice; Mutation; Osteoporosis; Polymorphism, Genetic; Proline; Serine; Sex Factors; TRPV Cation Channels | 2009 |
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.
Topics: Alanine; Amelogenesis; Amelogenin; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dental Enamel; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Histidine; Kallikreins; Matrix Metalloproteinase 20; Proline; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine; Tandem Mass Spectrometry; Tryptophan | 2009 |
Mapping the phosphorylation sites of Ulk1.
Topics: Amino Acid Sequence; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Line; Chromatography, Liquid; Humans; Mice; Molecular Sequence Data; Phosphorylation; Proline; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Tandem Mass Spectrometry | 2009 |
The pandemic 2009 (H1N1) swine influenza virus is mild compared to the pandemic 1918 (H1N1) virus because of a proline-to-serine substitution in the receptor-binding site of its hemagglutinin - a hypothesis.
Topics: Amino Acid Substitution; Binding Sites; Disease Outbreaks; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Incidence; Influenza A Virus, H1N1 Subtype; Influenza, Human; Models, Biological; Proline; Serine; Species Specificity | 2010 |
Defective O-glycosylation due to a novel homozygous S129P mutation is associated with lack of fibroblast growth factor 23 secretion and tumoral calcinosis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calcinosis; Carrier State; Chlorocebus aethiops; Codon; COS Cells; DNA Primers; Exons; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glycosylation; Homozygote; Humans; Hypophosphatemia, Familial; Molecular Sequence Data; Neoplasms; Polymorphism, Single Nucleotide; Proline; Serine | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells.
Topics: Amino Acid Substitution; Catalytic Domain; Cell Line; Dithiothreitol; Glutathione; Humans; Iodide Peroxidase; Kidney; Kinetics; Liver; Proline; Propylthiouracil; Serine; Thyroxine; Transfection | 2010 |
The products of pronase digestion of purified blood group-specific glycoproteins.
Topics: Blood Group Antigens; Chromatography, Gel; Galactosamine; Glucosamine; Glycoproteins; Glycosides; Humans; Hydrolysis; Peptide Hydrolases; Proline; Pronase; Sepharose; Serine; Sulfur; Threonine; Time Factors; Ultracentrifugation | 1973 |
Early behavioural markers of disease in P301S tau transgenic mice.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Cues; Disease Models, Animal; Exploratory Behavior; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Proline; Rotarod Performance Test; Serine; Spinal Cord; tau Proteins; Tauopathies; Visual Perception; Vocalization, Animal | 2010 |
Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.
Topics: Biological Transport; Cell Membrane; Epidermal Growth Factor; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Isoleucine; Mutation; Proline; Protein Structure, Tertiary; Serine; Signal Transduction; Translocation, Genetic; Wound Healing | 2010 |
D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO).
Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioma; Minor Histocompatibility Antigens; Proline; Pyruvic Acid; Racemases and Epimerases; Rats; RNA Interference; RNA, Messenger; Serine; Tritium | 2010 |
Metal cation dependence of interactions with amino acids: bond energies of Rb+ to Gly, Ser, Thr, and Pro.
Topics: Amino Acids; Cations; Glycine; Proline; Rubidium; Serine; Tandem Mass Spectrometry; Thermodynamics; Threonine; Xenon | 2010 |
Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; cdc25 Phosphatases; Epitopes; Female; Immunoblotting; Mitogen-Activated Protein Kinases; Mitosis; Oocytes; Phosphorylation; Proline; Recombinant Fusion Proteins; Serine; Threonine; Xenopus; Xenopus Proteins | 2010 |
Synthesis of syn-gamma-amino-beta-hydroxyphosphonates by reduction of beta-ketophosphonates derived from L-proline and L-serine.
Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Organophosphonates; Oxidation-Reduction; Proline; Serine; Stereoisomerism | 2010 |
Cell-mediated neuroprotection in a mouse model of human tauopathy.
Topics: Age Factors; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Transplantation; Cell- and Tissue-Based Therapy; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Growth Factor; Nerve Tissue Proteins; Neurons; Oligodendrocyte Transcription Factor 2; Proline; RNA, Messenger; Serine; Stem Cells; tau Proteins; Tauopathies | 2010 |
Mouse cytosolic sulfotransferase SULT2B1b interacts with cytoskeletal proteins via a proline/serine-rich C-terminus.
Topics: Amino Acid Sequence; Animals; Cytoskeletal Proteins; Cytoskeleton; Mice; Molecular Chaperones; NIH 3T3 Cells; Peptide Mapping; Proline; Protein Binding; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Serine; Sulfotransferases | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Correlation between genotype and supernumerary tooth formation in cleidocranial dysplasia.
Topics: Adenine; Adolescent; Adult; Arginine; Child; Cleidocranial Dysplasia; Core Binding Factor Alpha 1 Subunit; Diseases in Twins; DNA Copy Number Variations; Epigenesis, Genetic; Female; Frameshift Mutation; Genetic Heterogeneity; Genetic Variation; Genotype; Glutamine; Humans; Male; Middle Aged; Mutagenesis, Insertional; Mutation; Mutation, Missense; Point Mutation; Proline; Serine; Thymine; Tooth, Supernumerary; Twins, Monozygotic | 2010 |
Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets.
Topics: Amino Acid Substitution; Glycine; Humans; Islet Amyloid Polypeptide; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Structure, Secondary; Serine | 2010 |
Cleft lip with cleft palate, ankyloglossia, and hypodontia are associated with TBX22 mutations.
Topics: Adolescent; Anodontia; Arginine; Child; Child, Preschool; Cleft Lip; Cleft Palate; Cohort Studies; Conserved Sequence; DNA-Binding Proteins; Exons; Female; Genetic Variation; Glutamine; Humans; Labial Frenum; Leucine; Male; Mutation, Missense; Phenotype; Polymorphism, Genetic; Proline; Promoter Regions, Genetic; Serine; T-Box Domain Proteins; Tongue Diseases; Transcription, Genetic; Tryptophan; Tyrosine | 2011 |
The ALS8-associated mutant VAPB(P56S) is resistant to proteolysis in neurons.
Topics: Amino Acid Substitution; Animals; Animals, Newborn; Biological Transport; Cell Death; Cerebral Cortex; Embryo, Mammalian; Endoplasmic Reticulum; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; Membrane Proteins; Microscopy, Electron, Transmission; Molecular Weight; Mutation; Neuroglia; Neurons; Proline; Rats; RNA, Messenger; Serine; Subcellular Fractions; Synaptophysin; Transfection; Unfolded Protein Response | 2011 |
Influence of Ser/Pro-rich domain and kinase domain of double cortin-like protein kinase on microtubule-binding activity.
Topics: Animals; Chlorocebus aethiops; COS Cells; Doublecortin Domain Proteins; Doublecortin-Like Kinases; Microtubule-Associated Proteins; Microtubules; Neuropeptides; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Zebrafish; Zebrafish Proteins | 2011 |
Development of chemically defined media supporting high cell density growth of Ketogulonicigenium vulgare and Bacillus megaterium.
Topics: Bacillus megaterium; Biomass; Biotin; Culture Media; Glycine; Niacin; Proline; Rhodobacteraceae; Serine; Sorbose; Sugar Acids; Threonine; Zea mays | 2011 |
Evolution of nuclear retinoic acid receptor alpha (RARα) phosphorylation sites. Serine gain provides fine-tuned regulation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Chlorocebus aethiops; COS Cells; Cyclin H; Evolution, Molecular; Humans; Immunoblotting; Mice; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphorylation; Phylogeny; Proline; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Sequence Alignment; Serine; Zebrafish | 2011 |
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.
Topics: Aged; Biomarkers; Case-Control Studies; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Membrane Glycoproteins; Middle Aged; Myocardial Infarction; Odds Ratio; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proline; Prospective Studies; Receptors, Complement; Risk Assessment; Risk Factors; RNA, Messenger; Serine | 2011 |
Nuclear import of early growth response-1 involves importin-7 and the novel nuclear localization signal serine-proline-serine.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; CHO Cells; Cricetinae; Cricetulus; Early Growth Response Protein 1; Humans; Karyopherins; Myocytes, Smooth Muscle; Nuclear Localization Signals; Proline; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Serine | 2011 |
Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.
Topics: Amino Acid Sequence; Circular Dichroism; Collagen; Crystallization; Crystallography, X-Ray; Glycine; Hydroxyproline; Molecular Conformation; Molecular Sequence Data; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 2011 |
Neuronal ceroid lipofuscinosis in Qatar: report of a novel mutation in ceroid-lipofuscinosis, neuronal 5 in the Arab population.
Topics: Adolescent; Animals; Child; DNA Mutational Analysis; Family Health; Female; Humans; Lysosomal Membrane Proteins; Male; Membrane Proteins; Mutation; Neuronal Ceroid-Lipofuscinoses; Proline; Qatar; Sequence Alignment; Serine | 2011 |
Determination of sodium benzoate by chiral ligand exchange CE based on its inhibitory activity in D-amino acid oxidase mediated oxidation of D-serine.
Topics: Coordination Complexes; D-Amino-Acid Oxidase; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Ligands; Oxidation-Reduction; Proline; Serine; Sodium Benzoate; Stereoisomerism; Zinc | 2011 |
Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations.
Topics: Binding Sites; Chemistry, Physical; Computer Simulation; Humans; Leucine; Models, Molecular; Peptide Fragments; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-mdm2; Serine; Solvents; Spectrum Analysis, Raman; Tumor Suppressor Protein p53 | 2011 |
Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Disease Models, Animal; Female; Functional Laterality; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Stem Cells; Phosphorylation; Proline; Serine; Stem Cell Transplantation; tau Proteins; Tauopathies; Time Factors | 2011 |
String kernels and high-quality data set for improved prediction of kinked helices in α-helical membrane proteins.
Topics: Animals; Computational Biology; Databases, Protein; Glycine; Humans; Membrane Proteins; Models, Molecular; Models, Statistical; Proline; Protein Structure, Secondary; Research Design; Serine; Support Vector Machine | 2011 |
Functional analysis of the human concentrative nucleoside transporter-1 variant hCNT1S546P provides insight into the sodium-binding pocket.
Topics: Amino Acid Sequence; Animals; Binding Sites; Dogs; Endoplasmic Reticulum; Genetic Variation; HeLa Cells; Humans; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Proline; Protein Binding; Protein Transport; Serine; Sodium | 2012 |
Discovery of a novel class of potent and orally bioavailable sphingosine 1-phosphate receptor 1 antagonists.
Topics: Administration, Oral; Amides; Angiogenesis Inhibitors; Aniline Compounds; Animals; Antineoplastic Agents; Biological Availability; Cell Line; Cell Proliferation; Dogs; Haplorhini; High-Throughput Screening Assays; Mice; Neovascularization, Pathologic; Proline; Rats; Receptors, Lysosphingolipid; Serine; Stereoisomerism; Xenograft Model Antitumor Assays | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
The serine-proline turn: a novel hydrogen-bonded template for designing peptidomimetics.
Topics: Hydrogen Bonding; Models, Molecular; Molecular Conformation; Peptidomimetics; Proline; Serine | 2012 |
Metal cation dependence of interactions with amino acids: bond energies of Cs+ to Gly, Pro, Ser, Thr, and Cys.
Topics: Cations; Cesium; Cysteine; Glycine; Proline; Quantum Theory; Serine; Threonine | 2012 |
Phosphorylation regulates assembly of the caspase-6 substrate-binding groove.
Topics: Apoptosis; Binding Sites; Caspase 6; Crystallography, X-Ray; Escherichia coli; Humans; Models, Molecular; Molecular Mimicry; Neurodegenerative Diseases; Phosphorylation; Proline; Protein Binding; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Repressor Proteins; Serine; Signal Transduction | 2012 |
A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer.
Topics: Cell Membrane; Cytochrome b Group; Dimerization; Heme; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Mutation; Oxygen; Photosystem II Protein Complex; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Spectrophotometry | 2012 |
Homozygous protein C deficiency with late onset venous thrombosis: identification and in vitro expression study of a novel Pro275Ser mutation.
Topics: Animals; Blood Coagulation; Chlorocebus aethiops; Consanguinity; COS Cells; DNA Mutational Analysis; Family Health; Female; HEK293 Cells; Homozygote; Humans; Male; Mutation; Pedigree; Proline; Protein C Deficiency; Reference Values; Serine; Venous Thrombosis; Young Adult | 2012 |
Specific serine-proline phosphorylation and glycogen synthase kinase 3β-directed subcellular targeting of stathmin 3/Sclip in neurons.
Topics: Animals; Cell Differentiation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HeLa Cells; Humans; Microtubules; Models, Biological; Neurites; Neurons; Phosphorylation; Proline; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Stathmin | 2012 |
Genetic association between obstructive bronchitis and enzymes of oxidative stress.
Topics: Adult; Arginine; Aryldialkylphosphatase; Bronchitis; Catechol O-Methyltransferase; Chi-Square Distribution; Child; Cohort Studies; Epoxide Hydrolases; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Germany; Histidine; Humans; Leucine; Lung Diseases, Obstructive; Male; Methionine; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Proline; Prospective Studies; Risk Factors; Serine; Smoking; Valine | 2012 |
Target site mutation and reduced translocation are present in a glyphosate-resistant Lolium multiflorum Lam. biotype from Spain.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Adaptation, Physiological; Amino Acid Sequence; Base Sequence; Biological Transport; Glycine; Glyphosate; Herbicides; Lolium; Molecular Sequence Data; Mutation; Plant Leaves; Proline; Serine; Shikimic Acid; Spain; Species Specificity; Stress, Physiological | 2012 |
Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.
Topics: Amino Acid Sequence; Casein Kinase II; HEK293 Cells; Humans; Membrane Transport Proteins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Peptidylprolyl Isomerase; Proline; Protein Binding; Protein Stability; Protein Structure, Tertiary; Serine; Ubiquitination | 2012 |
Drosophila heat shock response requires the JNK pathway and phosphorylation of mixed lineage kinase at a conserved serine-proline motif.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Female; Heat-Shock Response; Humans; JNK Mitogen-Activated Protein Kinases; Longevity; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Phosphorylation; Proline; Serine | 2012 |
Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1.
Topics: Cell Survival; Models, Molecular; Phosphorylation; Proline; Protein Binding; Protein Structure, Tertiary; RNA Polymerase II; RNA-Binding Proteins; RNA, Untranslated; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2012 |
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
Topics: Acetylation; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Biomarkers; Brain; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Transgenic; Middle Aged; NIMA-Interacting Peptidylprolyl Isomerase; Oxidation-Reduction; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Processing, Post-Translational; Proteome; Serine; tau Proteins; Tauopathies | 2013 |
Convergent solid-phase synthesis of N-glycopeptides facilitated by pseudoprolines at consensus-sequence Ser/Thr residues.
Topics: Amino Acid Sequence; Aspartic Acid; Consensus Sequence; Glycopeptides; Molecular Sequence Data; Proline; Serine; Solid-Phase Synthesis Techniques; Threonine | 2012 |
Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis.
Topics: Amino Acid Substitution; Antifungal Agents; Candida tropicalis; Candidiasis; Clone Cells; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Glucosyltransferases; Homozygote; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proline; Sequence Analysis, DNA; Serine | 2013 |
Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model.
Topics: Animals; Antigens, Bacterial; Campylobacter jejuni; Gluconeogenesis; Glucose; Mice; Organ Specificity; Osmotic Pressure; Oxidative Stress; Proline; Serine | 2012 |
Protein tyrosine phosphatase with proline-glutamine-serine-threonine-rich motifs negatively regulates TLR-triggered innate responses by selectively inhibiting IκB kinase β/NF-κB activation.
Topics: Amino Acid Motifs; Animals; Cell Line; Cells, Cultured; Down-Regulation; Glutamine; HEK293 Cells; Humans; I-kappa B Kinase; Immunity, Innate; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; NF-kappa B; Proline; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Serine; Threonine; Tissue Distribution; Toll-Like Receptors | 2013 |
Reversal of elution order of N-(2,4-dinitrophenyl)-proline and N-(2,4-dinitrophenyl)-serine in HPLC by BSA chiral stationary phase.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Proline; Serine; Serum Albumin, Bovine; Stereoisomerism | 2013 |
p.Ser252Trp and p.Pro253Arg mutations in FGFR2 gene causing Apert syndrome: the first clinical and molecular report of Indonesian patients.
Topics: Acrocephalosyndactylia; Arginine; DNA Mutational Analysis; Fatal Outcome; Genetic Association Studies; Humans; Indonesia; Infant; Infant, Newborn; Male; Mutation; Proline; Receptor, Fibroblast Growth Factor, Type 2; Serine; Tryptophan | 2013 |
D-amino acid aberrations in cerebrospinal fluid and plasma of smokers.
Topics: Adult; Alanine; Alcohol Drinking; Excitatory Amino Acid Agonists; Female; Glycine; Humans; Male; Proline; Self Report; Serine; Smoking; Stereoisomerism | 2013 |
Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells.
Topics: Animals; Anoikis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Codon; Disease Progression; DNA, Neoplasm; Head and Neck Neoplasms; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; Proline; Reverse Transcriptase Polymerase Chain Reaction; Serine; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53 | 2013 |
PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Escherichia coli; Growth Hormone; Half-Life; Humans; Immunoglobulin Fab Fragments; Mice; Models, Molecular; Molecular Sequence Data; Peptides; Polyethylene Glycols; Proline; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine | 2013 |
Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.
Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Dendrites; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Motor Neurons; Mutation, Missense; Nerve Degeneration; Presynaptic Terminals; Proline; Serine; Spinal Cord; Unfolded Protein Response; Vesicular Transport Proteins | 2013 |
Exome sequencing identification of a GJB1 missense mutation in a kindred with X-linked spinocerebellar ataxia (SCA-X1).
Topics: Base Sequence; Chromosomes, Human, X; Connexins; Evolution, Molecular; Exome; Female; Gap Junction beta-1 Protein; Genes, X-Linked; Genetic Testing; Genetic Variation; HeLa Cells; Humans; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Phenotype; Phylogeny; Proline; Sequence Alignment; Sequence Analysis, DNA; Serine; Spinocerebellar Ataxias | 2013 |
A novel mutation (P236S) in the succinate dehydrogenase subunit B gene in a Japanese patient with a posterior mediastinal paraganglioma.
Topics: Aged; Amino Acid Substitution; Asian People; Female; Germ-Line Mutation; Humans; Mediastinal Neoplasms; Paraganglioma, Extra-Adrenal; Proline; Serine; Succinate Dehydrogenase | 2013 |
Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Chlorocebus aethiops; COS Cells; Endothelial Cells; Forkhead Transcription Factors; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Immunoblotting; Mice; Mice, Transgenic; Microscopy, Confocal; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Phosphorylation; Proline; Reverse Transcriptase Polymerase Chain Reaction; Serine; Threonine; Transcription, Genetic | 2013 |
Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.
Topics: Animals; Apoptosis; Arginine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Renal Cell; Cell Cycle Proteins; DNA Damage; DNA-Binding Proteins; Embryonic Stem Cells; Glutamine; Humans; Hypoxia-Inducible Factor 1; Immunohistochemistry; Kidney Neoplasms; Mice; Occupational Exposure; Point Mutation; Proline; Protein Array Analysis; Protein Serine-Threonine Kinases; Serine; Teratoma; Trichloroethylene; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2013 |
Chirality effects on proline-substituted serine octamers revealed by infrared photodissociation spectroscopy.
Topics: Photochemical Processes; Proline; Serine; Spectrophotometry, Infrared | 2014 |
Inhibition of serine and proline racemases by substrate-product analogues.
Topics: Amino Acid Isomerases; Clostridium sticklandii; Dose-Response Relationship, Drug; Enzyme Inhibitors; Models, Molecular; Molecular Structure; Proline; Racemases and Epimerases; Schizosaccharomyces; Serine; Structure-Activity Relationship | 2014 |
Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice.
Topics: Age Factors; Animals; Axonal Transport; Cognition Disorders; Disease Progression; Exploratory Behavior; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Mutation; Nerve Tissue Proteins; Phosphorylation; Proline; Recognition, Psychology; Serine; tau Proteins | 2014 |
A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant.
Topics: Acetylation; Amino Acid Substitution; Humans; N-Terminal Acetyltransferase A; N-Terminal Acetyltransferase E; N-Terminal Acetyltransferases; Phenotype; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Species Specificity | 2014 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Crystallography, X-Ray; Humans; Hydrogen Bonding; Molecular Conformation; Molecular Sequence Data; Phenotype; Prealbumin; Proline; Proteolysis; Serine | 2014 |
Serine and proline-rich ligands enriched via phage-display technology show preferential binding to BCR/ABL expressing cells.
Topics: Amino Acid Sequence; Animals; Cell Surface Display Techniques; Clone Cells; Fibroblasts; Fusion Proteins, bcr-abl; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Ligands; Mice; Molecular Sequence Data; NIH 3T3 Cells; Peptides; Proline; Protein Binding; Sequence Alignment; Serine; Transfection | 2014 |
Dorsal root ganglion neurons carrying a P301S Tau mutation: a valid in vitro model for screening drugs against tauopathies?
Topics: Animals; Drug Evaluation, Preclinical; Ganglia, Spinal; Humans; In Vitro Techniques; Mutation; Neurons; Proline; Serine; tau Proteins | 2014 |
Zygote serine decreased uptake from the fertilization medium is associated with implantation and pregnancy.
Topics: Adult; Cleavage Stage, Ovum; Culture Media; Embryo Implantation; Embryo Transfer; Female; Fertilization in Vitro; Humans; Pregnancy; Proline; Serine; Zygote | 2014 |
The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Culture Techniques; Cell Cycle; Cell Line; Cell Transdifferentiation; Fibroblasts; Gene Expression Regulation, Developmental; HEK293 Cells; Humans; Nerve Tissue Proteins; Neurogenesis; Neurons; Phosphorylation; Proline; Protein Processing, Post-Translational; Receptors, Notch; Serine; Signal Transduction; Xenopus laevis; Xenopus Proteins | 2014 |
Amine-catalyzed direct aldol reactions of hydroxy- and dihydroxyacetone: biomimetic synthesis of carbohydrates.
Topics: Amines; Biomimetics; Carbohydrates; Dihydroxyacetone; Glyceraldehyde; Molecular Structure; Proline; Serine; Stereoisomerism | 2014 |
[The influence of low partial oxygen pressure on the biolodical process of mesenchymal stromal cells].
Topics: Alanine; Aspartic Acid; Cell Hypoxia; Cell Line; Collagen; Culture Media; Glutamine; Humans; Hydroxyproline; Mesenchymal Stem Cells; Oxygen; Proline; Serine | 2014 |
Target-site basis for resistance to acetolactate synthase inhibitor in Water chickweed (Myosoton aquaticum L.).
Topics: Acetolactate Synthase; Amino Acid Substitution; Arylsulfonates; DNA, Plant; Herbicide Resistance; Herbicides; Plant Proteins; Proline; Serine; Stellaria | 2013 |
Structure of the cyclic peptide [W8S]contryphan Vn: effect of the tryptophan/serine substitution on trans-cis proline isomerization.
Topics: Amino Acid Sequence; Isomerism; Models, Molecular; Molecular Sequence Data; Peptides, Cyclic; Proline; Serine; Tryptophan | 2014 |
Combined correlation-based network and mQTL analyses efficiently identified loci for branched-chain amino acid, serine to threonine, and proline metabolism in tomato seeds.
Topics: Amino Acids, Branched-Chain; Chromosomes, Plant; Circadian Clocks; Computer Simulation; DNA, Plant; Gene Expression Regulation, Plant; Light; Metabolic Networks and Pathways; Metabolomics; Proline; Proline Oxidase; Quantitative Trait Loci; Seeds; Sequence Analysis, DNA; Serine; Solanum lycopersicum; Threonine | 2015 |
Classification of chemical chaperones based on their effect on protein folding landscapes.
Topics: Bacteria; Fluorescence Resonance Energy Transfer; Kinetics; Maltose-Binding Proteins; Methylamines; Models, Molecular; Proline; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Small Molecule Libraries; Thermodynamics; Trehalose | 2015 |
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.
Topics: Alternative Splicing; Amino Acid Sequence; Cell Nucleus; Conserved Sequence; Green Fluorescent Proteins; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Proline; Protein Conformation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Transport; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA Precursors; RNA-Binding Proteins; Serine; Serine-Arginine Splicing Factors; Substrate Specificity | 2015 |
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.
Topics: Adolescent; Adult; Alanine; Chromatography, Liquid; Female; Genetic Variation; Genome-Wide Association Study; Glycine; Humans; Male; Membrane Transport Proteins; Middle Aged; Proline; Proline Oxidase; Quantitative Trait Loci; Receptors, N-Methyl-D-Aspartate; Serine; Tandem Mass Spectrometry; Young Adult | 2015 |
Dynamical role of phosphorylation on serine/threonine-proline Pin1 substrates from constant force molecular dynamics simulations.
Topics: Diffusion; Friction; Isomerism; Kinetics; Molecular Dynamics Simulation; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Folding; Rotation; Serine; Threonine | 2015 |
α-Thalassemia associated with hb instability: a tale of two features. the case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Base Sequence; Child; DNA Mutational Analysis; Exons; Female; Genotype; Hemoglobins, Abnormal; Humans; Male; Middle Aged; Pedigree; Polymorphism, Single Nucleotide; Proline; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; RNA, Messenger; Serine; Threonine; Young Adult | 2015 |
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water | 2015 |
Impact of the hypoxia inducible factor-1α (HIF-1α) pro582ser polymorphism and its gene expression on diabetic foot ulcers.
Topics: Adult; Aged; Amino Acid Substitution; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Gene Frequency; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Proline; Serine | 2015 |
Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Disease Models, Animal; gamma-Synuclein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Proline; Pyramidal Tracts; Retina; Retinal Ganglion Cells; Serine; tau Proteins; Tauopathies; Visual Pathways | 2015 |
CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia.
Topics: Amyotrophic Lateral Sclerosis; Cohort Studies; Frontotemporal Dementia; Genetic Variation; Humans; Mitochondrial Proteins; Mutation; Penetrance; Proline; Serine | 2016 |
Improved Doxorubicin Encapsulation and Pharmacokinetics of Ferritin-Fusion Protein Nanocarriers Bearing Proline, Serine, and Alanine Elements.
Topics: Alanine; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Screening Assays, Antitumor; Drug Stability; Ferritins; Half-Life; Humans; Mice, Inbred BALB C; Nanocapsules; Peptides; Polyethylene Glycols; Proline; Recombinant Fusion Proteins; Serine | 2016 |
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.
Topics: Animals; Cell Line, Tumor; Cytoplasm; E1A-Associated p300 Protein; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Heparin-binding EGF-like Growth Factor; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Membrane Glycoproteins; Mice, Nude; Multiprotein Complexes; Neoplasm Proteins; Phosphorylation; Prognosis; Proline; Protein Serine-Threonine Kinases; Protein Stability; Protein-Tyrosine Kinases; RNA Interference; RNA, Long Noncoding; Serine; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Triple Negative Breast Neoplasms; Tyrosine | 2016 |
Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone.
Topics: Aldosterone; Amino Acid Substitution; Binding Sites; Conserved Sequence; Dexamethasone; Glutamine; HEK293 Cells; Humans; Hydrocortisone; Hydrogen Bonding; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Binding; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Serine; Structural Homology, Protein; Transcriptional Activation | 2016 |
Modulation of physicochemical and spectroscopic properties of l-serine and l-proline by propionate based food preservatives.
Topics: Food Preservatives; Proline; Propionates; Serine; Thermodynamics | 2016 |
Identification of SER-PRO-CYS Peptide in Blood Serum of Multiple Sclerosis Patients.
Topics: Adult; Amino Acid Sequence; Biomarkers; Cysteine; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Peptides; Proline; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Young Adult | 2016 |
Neighboring phosphoSer-Pro motifs in the undefined domain of IRAK1 impart bivalent advantage for Pin1 binding.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Binding, Competitive; Biosensing Techniques; Catalytic Domain; Interferometry; Interleukin-1 Receptor-Associated Kinases; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; NIMA-Interacting Peptidylprolyl Isomerase; Peptides; Phosphorylation; Proline; Protein Binding; Protein Domains; Serine | 2016 |
Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Animals; Cell Line, Tumor; Cell Proliferation; Exome Sequencing; Female; Genetic Predisposition to Disease; Humans; Janus Kinase 1; Male; Mice; Mice, Nude; Neoplasm Transplantation; Point Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Proline; Serine; Signal Transduction; Young Adult | 2017 |
A novel family of proline/serine-rich proteins, which are phospho-targets of stress-related mitogen-activated protein kinases, differentially regulates growth and pathogen defense in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Disease Resistance; Flagellin; Homeostasis; Mitogen-Activated Protein Kinases; Multigene Family; Mutation; Phosphorylation; Phylogeny; Plant Development; Plant Diseases; Plants, Genetically Modified; Proline; Protein Binding; Proteolysis; Pseudomonas syringae; Reactive Oxygen Species; Serine; Stress, Physiological; Subcellular Fractions; Substrate Specificity | 2017 |
Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation.
Topics: Acetylglucosamine; Amino Acid Motifs; Amino Acid Sequence; Glycosylation; Humans; Mass Spectrometry; N-Acetylglucosaminyltransferases; Phosphorylation; Proline; Protein Processing, Post-Translational; Proteins; Proteolysis; Serine; Signal Transduction; Threonine | 2017 |
Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model.
Topics: Animals; Carrier Proteins; Cerebral Cortex; Disease Models, Animal; Golgi Apparatus; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Transgenic; Neurofibrillary Tangles; Phosphopyruvate Hydratase; Phosphorylation; Proline; Pyramidal Cells; Receptors, Fibroblast Growth Factor; Serine; Sialoglycoproteins; tau Proteins; Tauopathies | 2017 |
Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design.
Topics: Antibodies, Monoclonal; Antibodies, Neutralizing; Antibodies, Viral; Capsid; Capsid Proteins; Drug Design; Epitopes; Humans; Mamastrovirus; Models, Molecular; Molecular Conformation; Mutation; Proline; Protein Binding; Sequence Analysis, DNA; Serine; Viral Vaccines | 2018 |
Prospects of PASylation® for the design of protein and peptide therapeutics with extended half-life and enhanced action.
Topics: Alanine; Animals; Drug Discovery; Half-Life; Humans; Models, Molecular; Peptides; Polyethylene Glycols; Proline; Serine | 2018 |
Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.
Topics: Amino Acid Motifs; Binding Sites; Drug Discovery; Humans; Isoleucine; Microtubule-Associated Proteins; Microtubules; Proline; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Maps; Serine | 2017 |
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Immunologic; Exploratory Behavior; Female; Frontotemporal Dementia; Hepatitis B Vaccines; Immunization; Immunodominant Epitopes; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Proline; Recognition, Psychology; Serine; tau Proteins; Treatment Outcome; Vaccines, Virus-Like Particle | 2018 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Stable Isotope Labeling of Prodiginines and Serratamolides Produced by Serratia marcescens Directly on Agar and Simultaneous Visualization by Matrix-Assisted Laser Desorption/Ionization Imaging High-Resolution Mass Spectrometry.
Topics: Agar; Ammonium Chloride; Carbon Isotopes; Depsipeptides; Deuterium; Isotope Labeling; Methionine; Nitrogen Isotopes; Prodigiosin; Proline; Serine; Serratia marcescens; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2018 |
Transcriptomic analysis of Campylobacter jejuni grown in a medium containing serine as the main energy source.
Topics: Adaptation, Physiological; Aspartic Acid; Campylobacter jejuni; Energy Metabolism; Gene Expression Profiling; Proline; Serine | 2019 |
Enhancing bioactivity, physicochemical, and pharmacokinetic properties of a nano-sized, anti-VEGFR2 Adnectin, through PASylation technology.
Topics: Alanine; Animals; Escherichia coli; Female; Fibronectins; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Mice; Mice, Inbred BALB C; Peptide Fragments; Proline; Protein Domains; Protein Engineering; Serine; Surface Plasmon Resonance; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line; Cholesterol; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Proline; Protein Binding; Protein Domains; Receptors, Steroid; Serine; Vimentin | 2019 |
Protective Effect of the
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Genotype; Glucose; HEK293 Cells; Humans; Hyperglycemia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Proline; Risk Factors; Serine; Transcriptional Activation; Young Adult | 2019 |
Why do eukaryotic proteins contain more intrinsically disordered regions?
Topics: Amino Acids; Animals; Computational Biology; Databases, Protein; Eukaryotic Cells; Evolution, Molecular; Humans; Intrinsically Disordered Proteins; Isoleucine; Prokaryotic Cells; Proline; Protein Domains; Selection, Genetic; Serine | 2019 |
Alteration in NMDAR-related amino acids in first episode psychosis.
Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
HBx natural variants containing Ser-101 instead of Pro-101 evade ubiquitin-dependent proteasomal degradation by activating proteasomal activator 28 gamma expression.
Topics: Autoantigens; Cell Line, Tumor; Gene Expression; Hepatitis B virus; Host-Pathogen Interactions; Humans; Mutant Proteins; Point Mutation; Proline; Proteasome Endopeptidase Complex; Proteolysis; Serine; Trans-Activators; Tumor Suppressor Protein p53; Ubiquitin; Viral Regulatory and Accessory Proteins; Virus Replication | 2019 |
Mistranslating tRNA identifies a deleterious S213P mutation in the
Topics: Acetyltransferases; Alleles; Mutation; Nuclear Proteins; Proline; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2020 |
Correlation of proline, hydroxyproline and serine content, denaturation temperature and circular dichroism analysis of type I collagen with the physiological temperature of marine teleosts.
Topics: Animals; Circular Dichroism; Collagen Type I; Fishes; Hydroxyproline; Proline; Protein Denaturation; Serine; Temperature | 2020 |
New Proline, Alanine, Serine Repeat Sequence for Pharmacokinetic Enhancement of Anti-VEGF Single-Domain Antibody.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Half-Life; HEK293 Cells; Humans; Mice; Mice, Inbred BALB C; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Single-Domain Antibodies; Tissue Distribution; Vascular Endothelial Growth Factor A | 2020 |
Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.
Topics: Adoptive Transfer; Animals; CD8-Positive T-Lymphocytes; Cell Engineering; Cell Line, Tumor; Cell Proliferation; Cystathionine gamma-Lyase; Cysteine; Extracellular Fluid; Female; Glycine; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Ovarian Neoplasms; Proline; Serine; Tumor Microenvironment | 2021 |
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry.
Topics: Amino Acid Motifs; Animals; Aurora Kinase A; Cell Cycle Proteins; Cell Line, Tumor; Cyclin A2; Cyclin-Dependent Kinase 2; Enzyme Activation; Female; Humans; Mitosis; Oocytes; Phosphorylation; Polo-Like Kinase 1; Proline; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serine; Threonine; Xenopus laevis | 2021 |
Proline-serine-threonine-repeat region of MDC1 mediates Chk1 phosphorylation and the DNA double-strand break repair.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Checkpoint Kinase 1; DNA Breaks, Double-Stranded; Humans; Phosphorylation; Proline; Serine; Threonine; Transfection | 2022 |
Cyclo(l-proline-l-serine) Dipeptide Suppresses Seed Borne Fungal Pathogens of Rice: Altered Cellular Membrane Integrity of Fungal Hyphae and Seed Quality Benefits.
Topics: Cell Membrane; Dipeptides; Fusarium; Hyphae; Oryza; Proline; Seeds; Serine | 2022 |
A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects.
Topics: Animals; Drosophila melanogaster; Female; Proline; Protein Biosynthesis; RNA, Transfer; Serine | 2022 |
Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.
Topics: Alanine; Amino Acids; Asparagine; Biomarkers; HIV Infections; Humans; Multiple Organ Failure; Proline; Serine | 2022 |
Serum metabolomic research of the anti-pulmonary fibrosis effects of Shuangshen Pingfei Formula on bleomycin-induced pulmonary fibrosis rats.
Topics: Animals; Biomarkers; Bleomycin; Chromatography, High Pressure Liquid; Metabolomics; Proline; Pulmonary Fibrosis; Rats; Serine | 2022 |
Two adjacent phosphorylation sites in the C-terminus of the channel's α-subunit have opposing effects on epithelial sodium channel (ENaC) activity.
Topics: Animals; Epithelial Sodium Channels; Glycogen Synthase Kinase 3 beta; Mice; Oocytes; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Rats; Serine; Xenopus laevis | 2022 |
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair.
Topics: Aminopeptidases; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA; DNA Damage; DNA Repair; Proline; Rad51 Recombinase; Serine | 2022 |
Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by
Topics: Anti-Bacterial Agents; Biological Products; Carbon; Mixed Function Oxygenases; Multigene Family; Proline; Pyrroles; Serine; Streptomyces | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors.
Topics: Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor Proteins; Ligands; Machine Learning; Molecular Docking Simulation; Proline; Reproducibility of Results; Serine; Threonine | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel-Lindau gene in the ccRCC.
Topics: Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Mutation, Missense; Proline; Serine; Von Hippel-Lindau Tumor Suppressor Protein | 2022 |
Separation of the enantiomers of underivatized amino acids by using serially connected dual column high-performance liquid chromatography-tandem mass spectrometry.
Topics: Acetonitriles; Amines; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crown Ethers; Cysteine; Ethanol; Humans; Methionine; Phenylalanine; Proline; Serine; Stereoisomerism; Tandem Mass Spectrometry; Water | 2022 |
A dominant negative mitofusin causes mitochondrial perinuclear clusters because of aberrant tethering.
Topics: Animals; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Proline; Serine | 2023 |
Urinary metabolomics, dietary salt intake and blood pressure: the African-PREDICT study.
Topics: Adult; African People; Amino Acids; Blood Pressure; Cardiovascular Diseases; gamma-Aminobutyric Acid; Humans; Hypertension; Proline; Serine; Sexually Transmitted Diseases; Sodium Chloride, Dietary | 2023 |
Metabolomic Aspects of Conservative and Resistance-Related Elements of Response to
Topics: Brachypodium; Flavonoids; Fusarium; Hordeum; Mycotoxins; Plant Diseases; Porphyrins; Proline; Pyrimidines; Serine; Triticum; Tryptophan | 2022 |
Efficient secretory production of proline/alanine/serine (PAS) biopolymers in Corynebacterium glutamicum yielding a monodisperse biological alternative to polyethylene glycol (PEG).
Topics: Alanine; Amino Acids; Biopolymers; Corynebacterium glutamicum; Peptides; Polyethylene Glycols; Proline; Serine | 2022 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Proline/serine-rich coiled-coil protein 1 inhibits macrophage inflammation and delays atherosclerotic progression by binding to Annexin A2.
Topics: Animals; Annexin A2; Atherosclerosis; Coronary Artery Disease; Inflammation; Macrophages; Mice; Mice, Knockout, ApoE; Phosphoproteins; Proline; Serine; Transcription Factors | 2023 |
Improving the isolated microspore culture in eggplant (Solanum melongena L.) with amino acid nutrition.
Topics: Alanine; Amino Acids; Glutamine; Proline; Serine; Solanum melongena | 2023 |
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-like/Wnt/β-Catenin Signaling.
Topics: beta Catenin; Carcinogenesis; Chromatography, Liquid; Colonic Neoplasms; Humans; Microtubule-Associated Proteins; Microtubules; Oxidoreductases; Proline; Protein Serine-Threonine Kinases; Serine; Tandem Mass Spectrometry; Wnt Signaling Pathway | 2023 |
Dietary amino acid intake and sleep duration are additively involved in future cognitive decline in Japanese adults aged 60 years or over: a community-based longitudinal study.
Topics: Aged; Aged, 80 and over; Amino Acids; Cognitive Dysfunction; Cystine; Diet; Diet Records; Dietary Proteins; Dyssomnias; East Asian People; Eating; Humans; Incidence; Independent Living; Longitudinal Studies; Middle Aged; Proline; Serine; Sleep; Sleep Duration; Surveys and Questionnaires | 2023 |