Compounds > proline

proline and prolinamide

proline has been researched along with prolinamide in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.44)18.7374
1990's0 (0.00)18.2507
2000's15 (36.59)29.6817
2010's20 (48.78)24.3611
2020's5 (12.20)2.80

Authors

AuthorsStudies
Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M1
Begley, DJ; Davson, H; Lipovac, MN; Rakić, L; Zloković, BV1
Chen, Z; Hobo, T1
Asano, Y; Harada, H; Komeda, H; Sakamoto, T; Ueda, M; Washika, S1
Breza, M; Fronc, M; Fuess, H; Kozísek, J; Paulmann, C; Popkov, A; Skubák, P1
Kawata, K; Nakagama, T; Nakajima, H; Shen, H; Uchiyama, K1
Guo, H; Li, H; Lou, B; Mei, Y; Wang, J; Wang, W; Xie, D; Xu, D1
Chen, JR; Cheng, L; Li, XY; Lu, HH; Wan, J; Xiao, WJ1
Dodda, R; Liu, J; Samanta, S; Zhao, CG1
Arai-Otsuki, S; Goto, Y; Ichikawa, D; Iwasawa, Y; Ohta, H; Okamoto, O; Okuda, S; Ozaki, S; Sagara, T; Tachibana, Y; Takahashi, H1
Dodda, R; Zhao, CG1
Hatayama, A; Kawabata, K; Kinoshita, A; Kondo, T; Nakai, H; Nekado, T; Ochi, K; Sugimoto, I; Takai, S; Toda, M; Yamamoto, S1
Feng, X; Hou, Z; Liu, X; Wang, J1
Kolev, T; Koleva, BB; Mayer-Figge, H; Seidel, RW; Sheldrick, WS; Spiteller, M1
Fredriksen, KA; Hansen, FK; Hansen, T; Kristensen, TE; Vestli, K1
Hadad, CM; Hyatt, SA; Mitsui, K; Parquette, JR; Turner, DA1
Coleman, PJ; Doran, SM; Fox, SV; Garson, SL; Gotter, AL; Koblan, KS; Levine, DM; Reiss, DR; Renger, JJ; Rigby, AM; Roecker, AJ; Tanis, KQ; Uebele, VN; Uslaner, JM; Winrow, CJ1
Gübitz, G; Pittler, E; Puchalska, P; Schmid, MG; Trojanowicz, M1
Gao, J; Jiang, D; Li, B; Liu, J; Tang, J; Yang, Q1
Han, J; Lu, Z; Mei, H; Pan, Y1
Mao, L; Qi, L; Qiao, J; Zhang, H1
Bozkurt, S; Durmaz, M; Naziroglu, HN; Sirit, A1
Alderton, W; Angell, AD; Beswick, PJ; Brown, D; Chambers, CL; Crowe, MC; Dawson, J; Hamlett, CC; Hodgson, ST; Kleanthous, S; Knowles, RG; Russell, LJ; Stocker, R; Woolven, JM; Young, RJ1
Bektaş, S; Caputo, R; De Nisco, M; Nucci, A; Pedatella, S1
Fotaras, S; Kokotos, CG; Kokotos, G1
Belema, M; Gao, M; Goodrich, J; Kakarla, R; Knipe, JO; Lemm, JA; Liu, M; Lopez, OD; Meanwell, NA; Nguyen, VN; Nower, PT; O'Boyle, D; Qiu, Y; Romine, JL; Serrano-Wu, MH; Snyder, LB; St Laurent, DR; Sun, JH; Valera, L; Yang, F; Yang, X1
Belema, M; Fridell, RA; Gao, M; Good, AC; Goodrich, JT; Lemm, JA; Liu, M; Lopez, OD; Meanwell, NA; Nguyen, VN; Nower, PT; O'Boyle, DR; Qiu, Y; Ripka, AS; Serrano-Wu, MH; Snyder, LB; St Laurent, DR; Sun, JH; Valera, L; Yang, F1
Bañón-Caballero, A; Guillena, G; Nájera, C1
Cui, Y; Qu, C; Zhang, L; Zhao, W1
Arivalagan, PR; Zhao, Y1
Bae, IH; Choe, W; Chough, C; Jang, SK; Keum, G; Kim, HS; Lee, SG; Moon Kim, B; Seon, MK; You, Y1
Bañn-Caballero, A; Flores-Ferrándiz, J; Guillena, G; Nájera, C1
Funabiki, K; Furuno, Y; Kubota, Y; Matsui, M; Sakaida, Y; Yano, Y1
Esmel, A; Frecer, V; Keita, M; Kone, M; Kouassi, AF; Megnassan, E; Miertus, S; N'Guessan, YT1
Chauhan, A; Dash, J; Debnath, M; Paladhi, S1
Abadi, AH; Abdel Karim, SE; Ahmed, NS; Frakolaki, E; Kamal, AAM; Ramsis, TM; Vassilaki, N; Zoidis, G1
Chauhan, A; Das, T; Dash, J; Debnath, M; Paul, R1
Anaya de Parrodi, C; de la Higuera Macías, M; Domínguez-Huerta, A; Hernández Pérez, JM; Huelgas, G; Rojas Cabrera, H; Sabala, R; Somanathan, R1
Kihara, T; Kobayashi, N; Koike, K; Sato, N; Sugawara, T; Sugita, K; Tada, Y; Yoshikawa, T1
Clement, C; Greiner, F; Schilz, J; Skerra, A1
Cao, L; Guo, HM; Xie, MS; Zhang, XP1

Other Studies

41 other study(ies) available for proline and prolinamide

ArticleYear
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
    Nature chemical biology, 2009, Volume: 5, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction

2009
Slow penetration of thyrotropin-releasing hormone across the blood-brain barrier of an in situ perfused guinea pig brain.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Animals; Bacitracin; Blood-Brain Barrier; Brain; Capillary Permeability; Female; Guinea Pigs; Hippocampus; Male; Mannitol; Parietal Lobe; Perfusion; Proline; Thyrotropin-Releasing Hormone

1988
Chemically L-prolinamide-modified monolithic silica column for enantiomeric separation of dansyl amino acids and hydroxy acids by capillary electrochromatography and mu-high performance liquid chromatography.
    Electrophoresis, 2001, Volume: 22, Issue:15

    Topics: Acetonitriles; Amino Acids; Buffers; Chromatography; Chromatography, High Pressure Liquid; Copper; Dansyl Compounds; Hydrogen-Ion Concentration; Hydroxy Acids; Indoles; Microscopy, Electron, Scanning; Proline; Silicon Dioxide; Stereoisomerism

2001
S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase.
    European journal of biochemistry, 2004, Volume: 271, Issue:8

    Topics: Amides; Amidohydrolases; Amino Acid Sequence; Amino Acids; Escherichia coli; Hydrolases; Hydrolysis; Molecular Sequence Data; Mycobacterium; Ochrobactrum anthropi; Piperazines; Proline; Pseudomonas; Pseudomonas putida; Recombinant Proteins; Sequence Alignment; Stereoisomerism; Substrate Specificity

2004
Electronic structure of the nickel(II) complex of the Schiff base of (S)-N-(2-benzoylphenyl)-1-benzylprolinamide and glycine.
    Acta crystallographica. Section A, Foundations of crystallography, 2004, Volume: 60, Issue:Pt 5

    Topics: Benzyl Compounds; Crystallography, X-Ray; Glycine; Models, Molecular; Nickel; Organometallic Compounds; Proline; Schiff Bases; Static Electricity

2004
Chiral separation of NBD-amino acids by ligand-exchange micro-channel electrophoresis.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2005, Volume: 21, Issue:1

    Topics: 4-Chloro-7-nitrobenzofurazan; Amino Acids; Copper; Electrophoresis, Microchip; Ligands; Proline; Stereoisomerism

2005
Direct, facile aldehyde and ketone alpha-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts.
    The Journal of organic chemistry, 2005, Jul-08, Volume: 70, Issue:14

    Topics: Aldehydes; Catalysis; Ketones; Models, Chemical; Proline; Pyrrolidines; Selenium; Stereoisomerism; Sulfonamides

2005
Readily tunable and bifunctional L-prolinamide derivatives: design and application in the direct enantioselective Aldol reactions.
    Organic letters, 2005, Sep-29, Volume: 7, Issue:20

    Topics: Aldehydes; Catalysis; Cyclohexanones; Drug Design; Molecular Structure; Proline; Stereoisomerism

2005
C2-symmetric bisprolinamide as a highly efficient catalyst for direct aldol reaction.
    Organic letters, 2005, Nov-10, Volume: 7, Issue:23

    Topics: Aldehydes; Catalysis; Molecular Structure; Proline; Stereoisomerism

2005
Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity.
    Journal of medicinal chemistry, 2006, Feb-09, Volume: 49, Issue:3

    Topics: Animals; Binding, Competitive; CHO Cells; Combinatorial Chemistry Techniques; Cricetinae; Cricetulus; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Structure; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Proline; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Opioid; Spiro Compounds; Stereoisomerism

2006
Organocatalytic highly enantioselective synthesis of secondary alpha-hydroxyphosphonates.
    Organic letters, 2006, Oct-12, Volume: 8, Issue:21

    Topics: Catalysis; Ketones; Molecular Structure; Organophosphonates; Proline; Stereoisomerism

2006
Discovery of long-acting N-(cyanomethyl)-N-alkyl-L-prolinamide inhibitors of dipeptidyl peptidase IV.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Blood Glucose; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enzyme Inhibitors; Humans; Proline; Stereoisomerism; Structure-Activity Relationship

2008
Highly enantioselective strecker reaction of ketoimines catalyzed by an organocatalyst from (S)-BINOL and L-prolinamide.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:15

    Topics: Catalysis; Imines; Molecular Conformation; Naphthols; Proline; Stereoisomerism

2008
Crystal structures and spectroscopic properties of ester amide and diamide of squaric acid with prolinamide.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 72, Issue:3

    Topics: Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Crystallography; Cyclobutanes; Diamide; Esters; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Proline; Protein Conformation; Protein Structure, Secondary; Spectrophotometry, Infrared; Tandem Mass Spectrometry; Thermogravimetry; Water; X-Ray Diffraction

2009
Synthesis of acrylic polymer beads for solid-supported proline-derived organocatalysts.
    Organic letters, 2009, Jul-16, Volume: 11, Issue:14

    Topics: Combinatorial Chemistry Techniques; Molecular Structure; Polymethacrylic Acids; Proline; Stereoisomerism

2009
Direct aldol reactions catalyzed by intramolecularly folded prolinamide dendrons: dendrimer effects on stereoselectivity.
    Chemical communications (Cambridge, England), 2009, Jun-14, Issue:22

    Topics: Aldehydes; Catalysis; Crystallography, X-Ray; Dendrimers; Proline; Stereoisomerism; Substrate Specificity

2009
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure.
    Neuropharmacology, 2010, Volume: 58, Issue:1

    Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Benzimidazoles; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Profiling; Gene Expression Regulation; Male; Motor Activity; Nicotine; Nicotinic Agonists; Oligonucleotide Array Sequence Analysis; Oligopeptides; Orexin Receptors; Proline; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement, Psychology; RNA, Messenger; Sleep; Transcription, Genetic; Ventral Tegmental Area

2010
Enantioseparation of amino acids and alpha-hydroxy acids on ligand-exchange continuous beds by capillary electrochromatography.
    Electrophoresis, 2010, Volume: 31, Issue:9

    Topics: Amino Acids; Capillary Electrochromatography; Dihydroxyphenylalanine; Hydroxy Acids; Hydroxyproline; Lactates; Phenylalanine; Proline; Stereoisomerism

2010
Chirally functionalized hollow nanospheres containing L-prolinamide: synthesis and asymmetric catalysis.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Jul-12, Volume: 16, Issue:26

    Topics: Catalysis; Hydrogen Bonding; Molecular Structure; Nanospheres; Organosilicon Compounds; Particle Size; Proline; Stereoisomerism; Surface Properties

2010
The mimic of type II aldolases chemistry: asymmetric synthesis of beta-hydroxy ketones by direct aldol reaction.
    Chemical biology & drug design, 2010, Volume: 76, Issue:2

    Topics: Benzaldehydes; Catalysis; Cyclohexanones; Fructose-Bisphosphate Aldolase; Ketones; Mesylates; Phenylenediamines; Proline; Stereoisomerism

2010
Determination of sodium benzoate by chiral ligand exchange CE based on its inhibitory activity in D-amino acid oxidase mediated oxidation of D-serine.
    Analytica chimica acta, 2011, Apr-08, Volume: 691, Issue:1-2

    Topics: Coordination Complexes; D-Amino-Acid Oxidase; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Ligands; Oxidation-Reduction; Proline; Serine; Sodium Benzoate; Stereoisomerism; Zinc

2011
Application of L-proline derivatives as chiral shift reagents for enantiomeric recognition of carboxylic acids.
    Chirality, 2011, Volume: 23, Issue:6

    Topics: Alanine; Amino Acids; Carboxylic Acids; Indicators and Reagents; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Molecular Structure; Nonlinear Dynamics; Proline; Stereoisomerism

2011
Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: Amidines; Enzyme Activation; Enzyme Inhibitors; Heme; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Nitric Oxide Synthase Type II; Proline

2011
D-Glucosamine in a chimeric prolinamide organocatalyst for direct asymmetric aldol addition.
    Carbohydrate research, 2012, Jul-15, Volume: 356

    Topics: Acetone; Aldehydes; Benzaldehydes; Carbohydrate Conformation; Catalysis; Cyclohexanones; Glucosamine; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Molecular Structure; Proline; Stereoisomerism

2012
A tripeptide-like prolinamide-thiourea as an aldol reaction catalyst.
    Organic & biomolecular chemistry, 2012, Aug-07, Volume: 10, Issue:29

    Topics: Aldehydes; Catalysis; Ethylenediamines; Hydrogen; Isomerism; Ketones; Oligopeptides; Proline; Stereoisomerism; Thiourea

2012
HCV NS5A replication complex inhibitors. Part 2: investigation of stilbene prolinamides.
    Bioorganic & medicinal chemistry letters, 2012, Oct-01, Volume: 22, Issue:19

    Topics: Antiviral Agents; Carbamates; Dose-Response Relationship, Drug; Imidazoles; Molecular Structure; Proline; Pyrrolidines; Stilbenes; Structure-Activity Relationship; Valine; Viral Nonstructural Proteins; Virus Replication

2012
HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies.
    Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

    Topics: Antiviral Agents; Carbamates; Hepacivirus; Imidazoles; Inhibitory Concentration 50; Molecular Structure; Proline; Pyrrolidines; Structure-Activity Relationship; Valine; Viral Nonstructural Proteins; Virus Replication

2013
Solvent-free enantioselective Friedländer condensation with wet 1,1'-binaphthalene-2,2'-diamine-derived prolinamides as organocatalysts.
    The Journal of organic chemistry, 2013, Jun-07, Volume: 78, Issue:11

    Topics: Catalysis; Diamines; Molecular Structure; Naphthalenes; Proline; Stereoisomerism; Tacrine

2013
Preparation of immobilized L-prolinamide via enzymatic polymerization of phenolic L-prolinamide and evaluation of its catalytic performance for direct asymmetric aldol reaction.
    Chirality, 2014, Volume: 26, Issue:4

    Topics: Aldehydes; Benzaldehydes; Biochemistry; Catalysis; Cyclohexanones; Horseradish Peroxidase; Polymerization; Proline; Stereoisomerism

2014
Interfacial catalysis of aldol reactions by prolinamide surfactants in reverse micelles.
    Organic & biomolecular chemistry, 2015, Jan-21, Volume: 13, Issue:3

    Topics: Aldehydes; Catalysis; Hydrogen Bonding; Micelles; Proline; Surface-Active Agents; Water

2015
Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Animals; Antiviral Agents; Benzidines; Cells, Cultured; Dose-Response Relationship, Drug; Female; Hepacivirus; Humans; Male; Microbial Sensitivity Tests; Molecular Structure; Proline; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Viral Nonstructural Proteins

2015
Enantioselective solvent-free synthesis of 3-alkyl-3-hydroxy-2-oxoindoles catalyzed by binam-prolinamides.
    Molecules (Basel, Switzerland), 2015, Jul-16, Volume: 20, Issue:7

    Topics: Catalysis; Cyclohexanones; Indoles; Isatin; Ketones; Molecular Structure; Proline; Stereoisomerism

2015
A Direct, Concise, and Enantioselective Synthesis of 2-Substituted 4,4,4-Trifluorobutane-1,3-diols Based on the Organocatalytic In Situ Generation of Unstable Trifluoroacetaldehyde.
    Chemistry, an Asian journal, 2015, Volume: 10, Issue:12

    Topics: Acetaldehyde; Aldehydes; Borohydrides; Butylene Glycols; Catalysis; Ketones; Methylene Chloride; Oxidation-Reduction; Proline; Stereoisomerism

2015
Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic Profiles.
    International journal of molecular sciences, 2015, Dec-12, Volume: 16, Issue:12

    Topics: Amino Acid Sequence; Bacterial Proteins; Cyclic N-Oxides; Enzyme Inhibitors; Molecular Sequence Data; Oxidoreductases; Proline; Quantitative Structure-Activity Relationship; Small Molecule Libraries

2015
Selective recognition of c-MYC G-quadruplex DNA using prolinamide derivatives.
    Organic & biomolecular chemistry, 2016, Jun-28, Volume: 14, Issue:24

    Topics: DNA; Drug Design; G-Quadruplexes; Hep G2 Cells; Humans; Ligands; Models, Molecular; Proline; Proto-Oncogene Proteins c-myc; Substrate Specificity; Triazoles

2016
Expanding the chemical space of anti-HCV NS5A inhibitors by stereochemical exchange and peptidomimetic approaches.
    Archiv der Pharmazie, 2018, Volume: 351, Issue:7

    Topics: Amino Acids; Antiviral Agents; Benzidines; Genotype; Hepacivirus; Peptidomimetics; Proline; Stereoisomerism; Structure-Activity Relationship; Viral Nonstructural Proteins

2018
G-Quadruplex-Binding Small Molecule Induces Synthetic Lethality in Breast Cancer Cells by Inhibiting c-MYC and BCL2 Expression.
    Chembiochem : a European journal of chemical biology, 2020, 04-01, Volume: 21, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Female; G-Quadruplexes; Humans; Ligands; Proline; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; S Phase Cell Cycle Checkpoints; Small Molecule Libraries; Synthetic Lethal Mutations

2020
Homochiral bifunctional L-prolinamide- and L-bis-prolinamide-catalyzed asymmetric aldol reactions performed in wet solvent-free conditions.
    Chirality, 2021, Volume: 33, Issue:1

    Topics: Acetone; Aldehydes; Catalysis; Chemistry Techniques, Synthetic; Density Functional Theory; Ketones; Molecular Structure; Proline; Solvents; Stereoisomerism; Thiourea

2021
Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide.
    Chemical & pharmaceutical bulletin, 2021, Volume: 69, Issue:4

    Topics: Administration, Oral; Animals; Body Temperature Regulation; Hypothermia; Male; Proline; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone

2021
Direct Affinity Purification of Long-Acting PASylated Proteins with Therapeutic Potential Using L-Prolinamide for Mild Elution.
    Angewandte Chemie (International ed. in English), 2022, 06-20, Volume: 61, Issue:25

    Topics: Antibodies; Chromatography, Affinity; Half-Life; Proline

2022
Cu-Catalyzed
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: Catalysis; Molecular Structure; Proline; Stereoisomerism

2023