proline has been researched along with methotrexate in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roberts, WK; Talmage, DW; Thomas, DW | 1 |
| Frank, N; Osswald, H | 1 |
| Chojkier, M; Laine, L | 1 |
| Fukui, K; Halprin, K; Marks, R | 1 |
| Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
| Auerbach, G; Bader, G; Dams, T; Huber, R; Jacob, U; Jaenicke, R; Ploom, T | 1 |
| Cole, SP; Conseil, G; Deeley, RG; Koike, K; Leslie, EM | 1 |
| Barnes, NC; Bradford, TM; Cambier, JC; Hogarth, PM; Musgrave, IF; Powell, MS; Wines, BD | 1 |
| Cole, SP; Deeley, RG; Létourneau, IJ; Slot, AJ | 1 |
| Cole, SP; Deeley, RG; Létourneau, IJ; Nakajima, A | 1 |
| Patel, N; Shah, A; Wu, Z; Yuan, X | 1 |
| Stephenson, A; Wu, Z; Yuan, X | 1 |
12 other study(ies) available for proline and methotrexate
| Article | Year |
|---|---|
Antibody synthesis in synchronized mouse spleen cells during the secondary response to sheep erythrocytes in vitro.
Topics: Adenosine; Animals; Antibody Formation; Antigens; Cells, Cultured; Colchicine; Dactinomycin; Erythrocytes; Immunologic Memory; Lymphocyte Activation; Lymphocytes; Methotrexate; Mice; Mitosis; Proline; Protein Hydrolysates; Sheep; Spleen; Tritium | 1975 |
Sacrosine- and prolinedithiocarbamate pretreatment increases the therapeutic efficacy of doxorubicin, methotrexate, teniposide, mitoxantrone or cyclohexylchloroethylnitrosourea in leukemia L1210.
Topics: Animals; Antineoplastic Agents; Cysteine; Doxorubicin; Drug Synergism; Female; Leukemia L1210; Lomustine; Methotrexate; Mice; Mice, Inbred DBA; Mitoxantrone; Proline; Sarcosine; Teniposide; Thiocarbamates | 1990 |
Hepatic collagen production in the rat is unaffected by methotrexate.
Topics: Animals; Collagen; Liver; Methotrexate; Proline; Rats; Triglycerides | 1986 |
The application of an in vitro technique to the study of epidermal replication and metabolism.
Topics: Culture Techniques; DNA; Folic Acid Antagonists; Growth Inhibitors; Histidine; Humans; Methods; Methotrexate; Nucleosides; Proline; Protein Biosynthesis; Psoriasis; RNA; Skin; Thymidine; Tritium | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Crystallography, X-Ray; Dimerization; Enzyme Stability; Folic Acid Antagonists; Ligands; Methotrexate; Models, Molecular; Molecular Sequence Data; NADP; Proline; Protein Structure, Quaternary; Protein Structure, Secondary; Sequence Alignment; Solubility; Static Electricity; Tetrahydrofolate Dehydrogenase; Thermodynamics; Thermotoga maritima | 2000 |
Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Anions; Biological Transport; Blotting, Northern; Cell Line; Cell Membrane; Cytoplasm; Dose-Response Relationship, Drug; Genetic Vectors; Humans; Kidney; Kinetics; Methotrexate; Microscopy, Confocal; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Nucleotides; Proline; Protein Binding; Protein Transport; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Substrate Specificity; Transfection; Vanadates | 2004 |
Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding.
Topics: Animals; Antigens, CD; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Dimerization; Down-Regulation; Humans; Immunoglobulin G; Ligands; Methotrexate; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Proline; Receptors, IgG; Serine; Signal Transduction; Tetrahydrofolate Dehydrogenase | 2006 |
Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
Topics: Adenosine Triphosphate; Azides; Binding Sites; Cations, Divalent; Cell Line; Cell Membrane; Estradiol; Humans; Leukotriene C4; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation, Missense; Photochemistry; Proline; Protein Binding; Transfection; Vanadates | 2007 |
Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.
Topics: Cell Line; Estradiol; Humans; Leukotriene C4; Methotrexate; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Proline; Protein Structure, Tertiary; Transfection; Transport Vesicles; Trypsin | 2008 |
Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cells.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Methotrexate; Prodrugs; Proline | 2010 |
The preformulation stability studies of a proline prodrug of methotrexate.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Methotrexate; Molecular Structure; Prodrugs; Proline | 2012 |