proline and isoquinoline

proline has been researched along with isoquinoline in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cregge, RJ; Durham, SL; Farr, RA; Gallion, SL; Hare, CM; Hoffman, RV; Janusz, MJ; Kim, HO; Koehl, JR; Mehdi, S; Metz, WA; Peet, NP; Pelton, JT; Schreuder, HA; Sunder, S; Tardif, C	1
Brookfield, FA; Courtney, SM; Dominguez, C; Eustache, FM; Gemkow, MJ; Handel, RK; Johnson, LC; Johnson, PD; Kerry, MA; Krieger, F; Maillard, MC; Meniconi, M; Muñoz-Sanjuán, I; Palfrey, JJ; Park, H; Schaertl, S; Taylor, MG; Weddell, D	1

Other Studies

2 other study(ies) available for proline and isoquinoline

Article	Year
Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones. Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14 Topics: Administration, Oral; Animals; Azetidines; Binding Sites; Cricetinae; Crystallography, X-Ray; Drug Design; Fluorocarbons; Hemorrhage; Humans; Isoquinolines; Ketones; Leukocyte Elastase; Lung Diseases; Models, Molecular; Molecular Conformation; Neutrophils; Oligopeptides; Pancreatic Elastase; Proline; Serine Proteinase Inhibitors; Structure-Activity Relationship; Swine	1998
Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19 Topics: Binding Sites; Caspase 2; Caspase 3; Caspase Inhibitors; Catalytic Domain; Cell Line; Cysteine Proteinase Inhibitors; Drug Design; Humans; Isoquinolines; Molecular Dynamics Simulation; Piperidines; Proline; Substrate Specificity	2011

Article

Year

Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.

Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

Topics: Administration, Oral; Animals; Azetidines; Binding Sites; Cricetinae; Crystallography, X-Ray; Drug Design; Fluorocarbons; Hemorrhage; Humans; Isoquinolines; Ketones; Leukocyte Elastase; Lung Diseases; Models, Molecular; Molecular Conformation; Neutrophils; Oligopeptides; Pancreatic Elastase; Proline; Serine Proteinase Inhibitors; Structure-Activity Relationship; Swine

1998

Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors.

Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

Topics: Binding Sites; Caspase 2; Caspase 3; Caspase Inhibitors; Catalytic Domain; Cell Line; Cysteine Proteinase Inhibitors; Drug Design; Humans; Isoquinolines; Molecular Dynamics Simulation; Piperidines; Proline; Substrate Specificity

2011