proline and gzr 123

proline has been researched along with gzr 123 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asmakova, LS; Bondarenko, NA; Gudasheva, TA; Kalinina, TS; Ostrovskaya, RU; Seredenin, SB; Voronina, TA; Zaitseva, NI1
Bondarenko, NA; Gudasheva, TA; Guzevatykh, LS; Ostrovskaya, RU; Retyunskaya, MV; Voronina, TA1
Gudasheva, TA; Klodt, PM; Kudrin, VS; Narkevich, VB; Ostrovskaia, RU; Shubenina, EV1
Gudasheva, TA1
Bastrygin, DV; Boyko, SS; Mesonzhnik, NV; Zherdev, VP1
Gudasheva, TA; Klodt, PM; Kudrin, VS; Kuznetsova, EA; Narkevich, VB; Ostrovskaya, RU; Shubenina, EV1
Boĭko, SS; Ivashkina, NIu; Kolyvanov, GB; Litvin, AA; Neznamov, GG; Serebrova, SIu; Shevchenko, RV; Siuniakov, SA; Zherdev, VP1
Gorelov, PI; Ostrovskaia, RU; Sazonova, NM1
Cherniakova, IV; Gudasheva, TA; Klodt, PM; Kolik, LG; Konstantinopol'skiĭ, MA; Kudrin, VS1
Boĭko, SS; Kolyvanov, GB; Litvin, AA; Shevchenko, RV; Zherdev, VP1
Kolyvanov, GB; Litvin, AA; Shevchenko, RV; Smirnov, VV; Zherdev, VP1

Trials

1 trial(s) available for proline and gzr 123

ArticleYear
[Specific features in pharmacokinetics of the original neuroleptic dilept in animals and humans].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:7

    Topics: Adult; Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Proline; Rabbits; Rats; Tyrosine

2014

Other Studies

10 other study(ies) available for proline and gzr 123

ArticleYear
Comparison of antipsychotic activity and discriminative stimulus effects of the novel acylprolyltyrosine containing compound, GZR-123, and sulpiride.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Discrimination, Psychological; Dopamine Agents; Dopamine Agonists; Exploratory Behavior; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Proline; Rats; Rats, Wistar; Stereotyped Behavior; Sulpiride; Tyrosine

1999
Neuromodulatory mechanism underlying the effect of the atypical dipeptide neuroleptic dilept.
    Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:5

    Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Behavior, Animal; Brain; Ketamine; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Proline; Schizophrenia; Tyrosine

2003
[Effect of dipeptide neurotensin analog dilept on extracellular concentrations of glutamate, GABA and HVA in N. accumbens of rat brain].
    Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:12

    Topics: Animals; Antipsychotic Agents; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Neurotensin; Nucleus Accumbens; Proline; Rats; Rats, Wistar; Tyrosine

2010
[Strategy for the development of dipeptide drugs].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2011, Issue:7

    Topics: Biological Availability; Biopharmaceutics; Blood-Brain Barrier; Dipeptides; Drug Design; Humans; Nootropic Agents; Piracetam; Proline; Protein Conformation; Psychotropic Drugs; Receptors, Cell Surface; Sulpiride; Tyrosine

2011
Permeability of the blood-brain barrier for dilept and its active metabolite.
    Bulletin of experimental biology and medicine, 2011, Volume: 151, Issue:3

    Topics: Animals; Antipsychotic Agents; Biological Transport; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Male; Proline; Rats; Tandem Mass Spectrometry; Tyrosine

2011
Effects of neurotensin dipeptide analog dilept on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats.
    Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:5

    Topics: 4-Butyrolactone; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dopamine; Hydrazines; Neurons; Nucleus Accumbens; Proline; Rats; Rats, Wistar; Tyrosine

2012
[Clinic pharmacokinetics of a new original antipsychotic drug Dilept].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:6

    Topics: Adult; Antipsychotic Agents; Area Under Curve; Biotransformation; Drug Administration Schedule; Humans; Male; Proline; Tablets; Tyrosine

2013
[The study of procognitive effect of the potential antipsychotic, Dilept and its main metabolite, GZR-125 at the novel objects recognition test in rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:7

    Topics: Animals; Animals, Outbred Strains; Antipsychotic Agents; Behavior, Animal; Cholinergic Antagonists; Discrimination, Psychological; Learning; Male; Nootropic Agents; Pattern Recognition, Visual; Proline; Rats; Scopolamine; Tyrosine

2013
[Neurotensin NT (8- 13) dipeptide analog dilept increases the pain threshold and decreases the severity of morphine withdrawal syndrome in rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:10

    Topics: Animals; Dopamine; Frontal Lobe; Hypothalamus; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Pain; Pain Threshold; Peptide Fragments; Proline; Rats; Serotonin; Severity of Illness Index; Substance Withdrawal Syndrome; Tyrosine

2013
Comparison of pharmacokinetics and relative bioavailability of tablets and substance of new dipeptide neuroleptic dilept.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:6

    Topics: Animals; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Half-Life; Models, Statistical; Proline; Rabbits; Tablets; Time Factors; Tyrosine

2014