proline has been researched along with gamma-aminobutyric acid in 250 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (33.60) | 18.7374 |
| 1990's | 88 (35.20) | 18.2507 |
| 2000's | 23 (9.20) | 29.6817 |
| 2010's | 35 (14.00) | 24.3611 |
| 2020's | 20 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Felix, D; Künzle, H | 1 |
| Gould, GW; Measures, JC | 1 |
| Cotman, CW; Nadler, JV; Redburn, DA; Vaca, KW; White, WF | 1 |
| Usherwood, PN | 1 |
| Hertz, L; Krogsgaard-Larsen, P; Schousboe, A; Svenneby, G | 1 |
| Cuénod, M; Henke, H; Schenker, TM | 1 |
| Cowey, A; Kritzer, MF; Somogyi, P | 1 |
| Nicoll, RA; Solís, JM | 1 |
| Lambert, JD; Roepstorff, A | 1 |
| Black, JA; Kocsis, JD; Sakatani, K | 1 |
| Deakin, JF; Royston, MC; Simpson, MD; Slater, P | 1 |
| Freschi, JE; Kerrison, J | 1 |
| Cardinali, DP; González Burgos, G; Rosenstein, RE | 1 |
| Brahce, L; Gregor, VE; Lobbestael, SJ; Mayhugh, DR; Nugiel, D; Pavia, MR; Schwarz, RD; Taylor, CP; Vartanian, MG | 1 |
| Keithley, EM; Ryan, AF; Schwartz, IR; Wang, ZX | 1 |
| Anderson, GM; Craig, JS; During, MJ; Gallager, DW; Hernandez, TD | 1 |
| Masland, RH; O'Malley, DM; Sandell, JH | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS | 1 |
| Barolet, AW; Morris, ME | 1 |
| Ching, W; Hassan, AZ; Sakatani, K | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Bourdelais, A; Kalivas, PW | 1 |
| Balcar, VJ | 1 |
| Gordon-Weeks, PR; Taylor, J | 1 |
| Andrioli, GC; Bonanno, G; Raiteri, M; Ruelle, A | 1 |
| Czudek, C; Reynolds, GP | 1 |
| Brehm, L; Krogsgaard-Larsen, P; Nielsen, L | 1 |
| Ayer, DE; Blakeman, DP; Davis, JP; Im, WB | 1 |
| Andrews, HB; Czudek, C; Reynolds, GP | 1 |
| Kato, Y; Kawakishi, S; Uchida, K | 1 |
| Blakeman, DP; Davis, JP; Im, WB | 1 |
| Sved, AF; Sved, JC | 2 |
| Malchow, RP; Ripps, H | 1 |
| Bernardi, G; Calabresi, P; De Murtas, M; Mercuri, NB | 1 |
| Anderson, JJ; DiMicco, JA | 1 |
| Boismare, F; Daoust, M; Lhuintre, JP; Moore, N; Saligaut, C | 1 |
| Dingledine, R; Korn, SJ | 1 |
| Armstrong, WE; Sladek, CD | 1 |
| Schwartz, EA | 1 |
| Bockaert, J; Pin, JP; Yasumoto, T | 1 |
| Bonanno, G; Fedele, E; Fontana, G; Raiteri, M; Robino, G | 1 |
| Arakawa, T; Okada, Y | 2 |
| Althaus, JS; Martin, DL | 1 |
| Georgiev, V; Kambourova, T; Yonkov, D | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Santicioli, P; Selleri, S | 1 |
| Deakin, JF; Royston, MC; Simpson, MD; Skan, WJ; Slater, P | 1 |
| Goldin, SM; Turner, TJ | 1 |
| Dutar, P; Lamour, Y; Rascol, O | 1 |
| Hasser, EM; Haywood, JR; Segura, T; Shade, RE | 1 |
| Cross, AJ; Deakin, JF; Simpson, MD; Slater, P | 1 |
| Brennan, TJ; Haywood, JR; Hinojosa, C | 1 |
| del Rio, RM; Herreras, O; Lerma, J | 1 |
| Shepherd, D; Tyrer, NM | 1 |
| Amsler, U; Cuénod, M; Perschak, H; Siegfried, J; Vischer, A | 1 |
| Nicholson, RA; Strang, RH; Whitton, PS | 1 |
| Bockaert, J; Pin, JP | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Barbaresi, P; Cuénod, M; Rustioni, A | 1 |
| Dalkara, T | 1 |
| Ciesielski, L; Gobaille, S; Mandel, P; Molina, V | 1 |
| Hertz, L; Larsson, OM; Schousboe, A | 1 |
| Lindgren, S; Simmonds, MA | 1 |
| Forni, C; Halsey, MJ; Rostain, JC; Wardley-Smith, B | 1 |
| Debeljuk, L; Díaz, MC; Duvilanski, BH; Lasaga, M; Seilicovich, A | 1 |
| Catelli, JM; Sved, AF | 1 |
| Bernath, S; Zigmond, MJ | 1 |
| Falch, E; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A | 1 |
| Kehr, J; Ungerstedt, U | 1 |
| Kihara, M; Kubo, T | 1 |
| Debeljuk, L; del Carmen Diaz, M; Duvilanski, BH; Lasaga, M; Seilicovich, A | 1 |
| Dennis, BJ; Kerr, DI; Krantis, A | 1 |
| Ryan, AF; Schwartz, IR | 1 |
| Catelli, JM; Giakas, WJ; Sved, AF | 1 |
| Yazulla, S | 1 |
| Hambley, JW; Johnston, GA | 1 |
| Cañadas Correas, S; González González, MP; Massó Córdoba, JM; Oset Gasque, MJ | 1 |
| Limberger, N; Späth, L; Starke, K | 1 |
| Fredholm, BB; Jonzon, B | 1 |
| Brennan, TJ; Haywood, JR | 1 |
| Giacobini, E; Gutierrez, MD | 1 |
| Hablitz, JJ; Lebeda, FJ | 1 |
| Neuhoff, V; Osborne, NN | 1 |
| Makara, GB; Stark, E | 1 |
| Deisz, RA; Dose, M; Lux, HD | 1 |
| Lloyd, KG; Pilc, A | 1 |
| Osburn, LD; Peterson, NA; Raghupathy, E; Rhoads, DE | 1 |
| Peterson, NA; Raghupathy, E; Rhoads, DE | 1 |
| Johnson, JL; Roberts, E | 1 |
| Daldrup, T; Huckenbeck, W | 1 |
| Classen, K; Göthert, M; Schlicker, E | 1 |
| Brown, DA; Scholfield, CN | 1 |
| Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A; Thorbek, P | 1 |
| Madtes, P; Redburn, DA | 1 |
| Madtes, PC; Redburn, DA | 1 |
| Deisz, RA; Dose, M | 1 |
| Hernández, N; Holder, LG; Jaffé, EH | 1 |
| Ijima, S; Kadota, T; Matsuda, A; Miyata, T; Nagata, J; Okano, Y; Takahama, K | 1 |
| Moonsammy, GI; Rush, JA; Yunger, LM | 1 |
| Atkinson, HD; Little, HJ | 1 |
| Cherubini, E; North, RA | 1 |
| Horton, RW; Prestwich, SA; Spyrou, NA | 1 |
| del Rio, RM; Herranz, AS; Herreras, O; Lerma, J; Munoz, D | 1 |
| Bendahan, A; Kanner, BI; Radian, R | 1 |
| Drejer, J; Hertz, L; Larsson, OM; Schousboe, A | 1 |
| Arst, HN; Bailey, CR; Penfold, HA | 1 |
| Prusiner, SB | 1 |
| Szerb, JC | 1 |
| Giacobini, E; Nomura, Y; Okuma, Y; Schmidt-Glenewinkel, T; Segawa, T | 1 |
| Kovalev, GI; Raevskiĭ, KS | 1 |
| Larsson, OM; Schousboe, A | 1 |
| Van Harreveld, A | 1 |
| Copenhagen, DR; Kaneko, A; Miyoshi, S; Takahashi, K | 1 |
| Bindi, D; Franchi-Micheli, S; Gentilini, G; Mugnai, S; Zilletti, L | 1 |
| Brechtel, C; Fleming, SR; King, SC | 1 |
| Gill, SS; Mbungu, D; Ross, LS | 1 |
| Desmonts, JM; Henzel, D; Lecharny, JB; Mantz, J; Salord, F | 1 |
| Honmou, O; Kocsis, JD; Richerson, GB | 1 |
| Christensen, HN; Greene, AA; Kakuda, DK; MacLeod, CL | 1 |
| Desmonts, JM; Henzel, D; Laudenbach, V; Lecharny, JB; Mantz, J; Peytavin, G | 1 |
| Sharp, T; Smith, SE | 1 |
| Ijaz, S; Kanthan, R; Mainprize, T; Miyashita, H; Shuaib, A | 1 |
| Coffman, JA; Cooper, TG; el Berry, HM | 1 |
| Honmou, O; Kocsis, JD | 1 |
| Borden, LA; Branchek, TA; Dhar, TG; Gluchowski, C; Smith, KE; Tyagarajan, S; Weinshank, RL | 1 |
| Koga, T; Osawa, I; Saito, N; Tanaka, C | 1 |
| Björklund, A; Campbell, K; Kalén, P; Lundberg, C; Mandel, RJ; Wictorin, K | 1 |
| Munck, BG; Munck, LK; Polache, A; Rasmussen, SN | 1 |
| Aihara, N; Koide, K; Mabe, H; Mizukawa, K; Nishino, H | 1 |
| Chesler, M; Hassan, AZ; Lee, M; Sakatani, K; Young, W | 1 |
| Horvitz, HR; Jorgensen, E; McIntire, SL | 1 |
| Björklund, A; Campbell, K; Kalén, P; Lundberg, C; Rosengren, E; Wictorin, K | 1 |
| Kocsis, JD; Lim, JY; Sakatani, K; Utzschneider, DA | 1 |
| el Manira, A; Grillner, S; Matsushima, T; Tegnér, J | 1 |
| Malchow, RP; Qian, H; Ripps, H | 1 |
| Cooper, TG; Daugherty, JR; el Berry, HM; Rai, R | 1 |
| Liu, QR; López-Corcuera, B; Mandiyan, S; Nelson, H; Nelson, N | 1 |
| Lloyd, KG; Thuret, F; Vargas, F | 1 |
| Andersen, KE; Braestrup, C; Grønwald, FC; Jørgensen, AS; Knutsen, LJ; Nielsen, EB; Sonnewald, U; Suzdak, PD; Sørensen, PO | 1 |
| Honmou, O; Kocsis, JD; Oyelese, AA | 1 |
| Del Zotto, H; Etchegoyen, GS | 1 |
| Ijaz, S; Kalra, J; Kanthan, R; Mainprize, T; Miyashita, H; Shuaib, A | 1 |
| Horii, A; Mochizuki, T; Okakura-Mochizuki, K; Yamamoto, Y; Yamatodani, A | 1 |
| Brotchie, JM; Crossman, AR; Maneuf, YP | 1 |
| Draguhn, A; Heinemann, U; Meierkord, H; Pfeiffer, M | 1 |
| Fonnum, F; Fykse, EM | 1 |
| Chen, DZ; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Hashimoto, T; Kuriyama, K | 1 |
| Kolachana, BS; Saunders, RC; Weinberger, DR | 1 |
| Egebjerg, J; Sørensen, PO; Thomsen, C | 1 |
| Kelley, AE; Stratford, TR | 1 |
| Dobolyi, A; Juhász, G; Kékesi, KA; Krogsgaard-Larsen, P; Nyitrai, G; Schousboe, A | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Agulian, S; Kocsis, JD; Yee, JM | 1 |
| Abraini, JH; Bouquet, C; Cagniard, B; Kriem, B; Rostain, JC | 1 |
| Batlle, A; Bermúdez Moretti, M; Correa García, S | 1 |
| Castañeda, TR; Del Arco, A; Mora, F | 1 |
| Crook, JM; Eysel, UT; Kisvárday, ZF | 1 |
| Cherubini, E; Martina, M; Sciancalepore, M; Strata, F | 1 |
| Hemmings, HC; Murugaiah, KD | 1 |
| Falch, E; Frølund, BF; Krogsgaard-Larsen, P | 1 |
| Georgiev, V; Hadjiivanova, CH | 1 |
| Goshima, Y; Honjo, K; Misu, Y; Miyamae, T | 1 |
| Landmesser, LT; Milner, LD | 1 |
| Breitkreuz, KE; Fischer, WN; Rentsch, D; Schwacke, R; Shelp, BJ | 1 |
| Itoh, Y; Kimura, K; Kise, M; Mushiroi, T; Ogasawara, T; Tamura, M; Ukai, Y | 1 |
| Hanania, T; Johnson, KM | 1 |
| Arias-Montaño, JA; Bahena-Trujillo, R | 1 |
| Del Arco, A; Galindo, A; Mora, F | 1 |
| Reith, CA; Sillar, KT | 1 |
| Bouma, M; Davis, M; De Vries, JB; Timmerman, W; Westerink, BH | 1 |
| Frydenvang, K; Frølund, B; Krogsgaard-Larsen, P | 1 |
| Köfalvi, A; Sperlágh, B; Vizi, ES; Zelles, T | 1 |
| Baba, S; Hibino, T; Ishii, T; Ishikawa, H; Kawamitsu, Y; Matsuda, N; Meng, YL; Takabe, T; Tanaka, Y; Uehara, N; Wada, K | 1 |
| Agulhon, C; Darmon, M; El Mestikawy, S; Gasnier, B; Giros, B; Hamon, M; Ravassard, P; Sagné, C | 1 |
| Barnard, EA; Greenfield, LJ; Lummis, SC; Macdonald, RL; Niemeyer, MI; Sutherland, ML; Zaman, SH | 1 |
| MIZUSKI, S; NOGUCHI, M; TAMAKI, E | 1 |
| Brandsch, M; Kalbitz, J; Metzner, L | 1 |
| Barry, PH; Carland, JE; Chebib, M; Johnston, GA; Moorhouse, AJ | 1 |
| Grallath, S; Gumy, C; Meyer, A; Neuhaus, JM; Rentsch, D; Suter-Grotemeyer, M; Weimar, T | 1 |
| Fait, A; Fromm, H; Yellin, A | 1 |
| Carpes, MJ; Correia, CR; de Oca, AC; dos Santos, MA; Garcia, AL; Santana, CC | 1 |
| Hoefner, GC; Hoesl, CE; Wanner, KT; Zhao, X | 1 |
| Broumand, V; Enck, AH; Mercado, A; Mount, DB; Zandi-Nejad, K | 1 |
| Abbot, EL; Gatfield, KM; Grenade, DS; Kennedy, DJ; Thwaites, DT | 1 |
| Eskandari, S; Grallath, S; Meyer, A; Rentsch, D | 1 |
| Fülep, GH; Hoesl, CE; Höfner, G; Wanner, KT | 1 |
| Browning, KN; Gettys, TW; Travagli, RA; Zheng, Z | 1 |
| Cahusac, PM; Wan, H | 1 |
| Agrawal, GK; Fujihara, S; Iwahashi, H; Kim, du H; Kim, DW; Rakwal, R; Shibato, J; Shim, IeS | 1 |
| Gage, PW; Luu, T; Tierney, ML | 1 |
| Frølund, B; Larsen, BB; Larsen, M; Nielsen, CU | 1 |
| Fang, D; Guo, L; Lian, Y; Zhao, G; Zhao, X; Zhou, J; Zhuang, W | 1 |
| Cirou, A; Faure, D; Haudecoeur, E; Moréra, S; Planamente, S; Shelp, BJ; Tannières, M | 1 |
| Bilican, B; Chandran, S; Goedert, M; Hampton, DW; Spillantini, MG; Webber, DJ | 1 |
| Anderson, CM; Edwards, N; Ganapathy, V; Gatfield, KM; Jevons, MP; Thwaites, DT | 1 |
| Cai, Y; Cao, S; Shang, H; Yang, Z; Zheng, Y | 1 |
| Gudasheva, TA; Klodt, PM; Kudrin, VS; Narkevich, VB; Ostrovskaia, RU; Shubenina, EV | 1 |
| Bar, D; Fait, A; Fernie, AR; Fromm, H; Grillich, N; Khan, M; Lagor, K; Michaeli, S; Nunes-Nesi, A; Turano, FJ; Yellin, A | 1 |
| Liu, C; Yu, G; Zhao, L | 1 |
| Iovino, M; Spillantini, MG; Vuono, R | 1 |
| de Haan, P; Geertsema, EM; Miao, Y; Poelarends, GJ; Tepper, PG; Zandvoort, E | 1 |
| Bakker, HJ; Ottosson, N; Pastorczak, M; van der Post, ST | 1 |
| Berardocco, S; Deleu, C; Haury, J; Thiébaut, G; Thouvenot, L | 1 |
| Borsani, O; Coitiño, EL; Dans, PD; Monza, J; Signorelli, S | 1 |
| Kumar, A; Pandey, N; Shirke, PA; Singh, R | 1 |
| Aliani, M; House, JD; Mayengbam, S | 1 |
| Appel, K; Kuchta, K; Merten, A; Rauwald, HW; Rusch, C; Savtschenko, A | 1 |
| Barrio, RJ; De Diego, N; Lacuesta, M; Moncaleán, P; Pérez-Alfocea, P; Rodríguez, JL; Saiz-Fernández, I; Sampedro, MC | 1 |
| Luo, Z; Mao, L; Wang, Y; Ying, T | 1 |
| Holm, R; Lagunas, C; Nielsen, CU; Plum, J; Rasmussen, RN | 1 |
| Chinnici, F; Durán-Guerrero, E; Riponi, C | 1 |
| Antoine, S; Berti, L; Giannettini, J; Gibon, Y; Luro, F; Pailly, O; Santini, J | 1 |
| Deng, Z; Lei, G; Li, Y; Luo, W; Ren, W; Wu, G; Xiao, W; Zeng, C | 1 |
| Faure, D; Lang, J | 1 |
| Bian, K; Cao, S; Chen, W; Shao, J; Song, C; Yang, Z | 1 |
| Capozzi, F; Donnini, S; Picone, G; Rombolà, AD; Tessarin, P; Trimigno, A | 1 |
| Crabtree, GW; Gogos, JA; Gordon, JA; Park, AJ | 1 |
| Gonzalez-Burgos, G; Lewis, DA; Volk, DW | 1 |
| Ban, Z; Li, D; Li, L; Limwachiranon, J; Luo, Z; Wang, D; Xu, Y | 1 |
| Dewey, SL; Juncosa, JI; Le, HV; Liu, D; Mascarenhas, R; Moschitto, MJ; Silverman, RB; Takaya, K; Weerawarna, PM | 1 |
| Favero, DS; Imamura, J; Iwase, A; Kobayshi, M; Kojima, M; Kusano, M; Mita, K; Mitsuda, N; Oikawa, A; Saito, K; Sakakibara, H; Sasaki, R; Sugimoto, K; Takebayashi, Y | 1 |
| Crabtree, GW; Gogos, JA | 1 |
| Ingenito, G; Kondo, DG; Miller, SR; Prescot, AP; Prisciandaro, JJ; Renshaw, PF | 1 |
| Chen, S; Geng, L; Hu, X; Huang, H; Ji, X; Ren, L; Sun, X | 1 |
| Carvajal, F; Garrido, D; Jamilena, M; Jiménez-Muñoz, R; Palma, F; Pulido, A | 1 |
| Alberti, G; Castellarin, SD; Degu, A; Fait, A; Herrera, JC; Hochberg, U; Lazarovitch, N; Peterlunger, E; Wong, DCJ | 1 |
| Duan, Y; Jiao, C | 1 |
| Akolkar, B; Butterworth, MD; Fan, S; Fiehn, O; Hagopian, W; Krischer, JP; Lernmark, Å; Li, Q; Parikh, H; Rewers, M; She, JX; Toppari, J; Ziegler, AG | 1 |
| Chashmniam, S; Dalili, N; Kalantari, S; Nafar, M; Rezaie, D; Samavat, S | 1 |
| Fang, W; Liao, J; Ma, Y; Nong, S; Shen, Q; Wang, Y; Xing, A; Xiong, F; Zhu, X | 1 |
| Corsi-Zuelli, F; da Roza, DL; Del-Ben, CM; Deminice, R; Fachim, HA; Jordão, AA; Loureiro, CM; Louzada-Junior, P; Menezes, PR; Shuhama, R; Simões-Ambrosio, LMC | 1 |
| Kobayashi, T; Kobayashi, W; Kumakura, K; Matsuoka, H; Takahashi, A | 1 |
| Bor, M; Özdemir, F; Pelvan, A; Türkan, I; Yolcu, S | 1 |
| Aelaei, M; Mohammadi, M; Saidi, M | 1 |
| Kunzendorf, A; Poelarends, GJ; Saifuddin, M | 1 |
| Duan, X; Huang, H; Jiang, Y; Lin, X; Luo, Z; Soleimani Aghdam, M; Wang, D | 1 |
| Feng, G; Han, L; Hassan, MJ; Huang, L; Li, Z; Liu, L; Liu, W; Peng, Y; Tan, M | 1 |
| Ansari, Z; Barvkar, VT; Nadaf, AB; Renuka, N; Wang, C; Zhang, Y; Zhao, C | 1 |
| Arnoriaga-Rodríguez, M; Biarnés, C; Blasco, G; Brugada, R; Burokas, A; Castells-Nobau, A; Coll, C; de la Vega-Correa, L; Deco, G; Escrichs, A; Fernández-Real, JM; Garre-Olmo, J; Gich, J; Jové, M; Maldonado, R; Martin, M; Mayneris-Perxachs, J; Moreno-Navarrete, JM; Moya, A; Pamplona, R; Pedraza, S; Pérez-Brocal, V; Portero-Otin, M; Puig, J; Ramió-Torrentà, L; Ramos, R; Ricart, W; Serena, J; Sol, J; Vilanova, JC; Zapata, C | 1 |
| Bergman, M; Bodner, L; Bouchebti, S; Levin, E; Magory Cohen, T | 1 |
| Duan, M; Luo, H; Tang, X; Xie, H; Xing, P | 1 |
| Brodzki, M; Mozrzymas, JW | 1 |
| Dietz, KJ; García-Caparrós, P; Kumar, V; Persicke, M; Vogelsang, L; Wirtz, M | 1 |
| Gafane-Matemane, L; Jacobs, A; Kruger, R; Louw, R; Mbongwa, H; Mels, C; Mokwatsi, G; Pieters, M; Schutte, AE; Strauss-Kruger, M; van Zyl, T | 1 |
| Avila, C; Crosby, K; Ibrahim, AM; Marquez, SA; Patil, B; Pessoa, H; Singh, J | 1 |
| Bin, D; Fenqin, H; Lihe, Z; Shuochen, J; Xiangru, T | 1 |
| Bao, Y; Hou, Y; Jin, P; Liu, Y; Wu, Z; Yi, B; Zhao, Y; Zheng, Y | 1 |
9 review(s) available for proline and gamma-aminobutyric acid
| Article | Year |
|---|---|
The role of proline in nervous transmission.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebellum; gamma-Aminobutyric Acid; Glycine; Neurons; Neurotransmitter Agents; Organ Specificity; Proline; Strychnine | 1976 |
Water relations in single cells.
Topics: Bacillus; Bacterial Physiological Phenomena; Cell Division; Cell Physiological Phenomena; Cell Survival; gamma-Aminobutyric Acid; Glutamates; Halobacterium; Hot Temperature; Osmolar Concentration; Proline; Spores; Water; Water-Electrolyte Balance; Yeasts | 1977 |
Amino acids as neurotransmitters.
Topics: Amino Acids; Animals; Aspartic Acid; beta-Alanine; gamma-Aminobutyric Acid; Glutamates; Glycine; Membrane Potentials; Neural Inhibition; Neurotransmitter Agents; Proline; Receptors, Neurotransmitter; Species Specificity; Synaptic Membranes; Taurine | 1978 |
Neurohumoral mechanisms of sodium-dependent hypertension.
Topics: Animals; Arginine Vasopressin; Diet, Sodium-Restricted; gamma-Aminobutyric Acid; Humans; Hypertension; Hypertension, Renal; Neurotransmitter Agents; Nipecotic Acids; Proline; Saline Solution, Hypertonic; Sodium | 1985 |
Disorders of glutamate metabolism and neurological dysfunction.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Histidine; Humans; Ketoglutaric Acids; Nervous System Diseases; Proline; Pyrrolidonecarboxylic Acid | 1981 |
Special transport and neurological significance of two amino acids in a configuration conventionally designated as D.
Topics: Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Central Nervous System; gamma-Aminobutyric Acid; Humans; Proline; Stereoisomerism; Structure-Activity Relationship | 1994 |
Amino acid neurotransmission: dynamics of vesicular uptake.
Topics: Amino Acids; Animals; Aspartic Acid; beta-Alanine; Biological Transport; Central Nervous System; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Membrane Potentials; Neurotransmitter Agents; Proline; Synaptic Vesicles; Taurine | 1996 |
GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects.
Topics: Animals; Anticonvulsants; Behavior, Animal; Blood-Brain Barrier; Drug Design; gamma-Aminobutyric Acid; Humans; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Prodrugs; Proline; Structure-Activity Relationship | 2000 |
Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health.
Topics: Arginine; Creatinine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homoarginine; Humans; Hydroxyproline; Immunologic Factors; Inflammation; Nutritional Requirements; Nutritional Status; Osteoarthritis; Proline; Tryptophan | 2016 |
241 other study(ies) available for proline and gamma-aminobutyric acid
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
Characterization of putative amino acid transmitter release from slices of rat dentate gyrus.
Topics: Amino Acids; Animals; Aspartic Acid; Barium; Calcium; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Magnesium; Neurotransmitter Agents; Potassium; Proline; Rats; Sodium; Time Factors; Veratridine | 1977 |
Inhibition of the high-affinity, net uptake of GABA into cultured astrocytes by beta-proline, nipecotic acid and other compounds.
Topics: Alanine; Animals; Astrocytes; Brain; Cells, Cultured; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Nipecotic Acids; Proline | 1978 |
Effects of retinal ablation on uptake of glutamate, glycine, GABA, proline and choline in pigeon tectum.
Topics: Aminobutyrates; Animals; Binding Sites; Biological Transport, Active; Centrifugation, Density Gradient; Choline; Columbidae; gamma-Aminobutyric Acid; Glutamates; Glycine; Kinetics; Mitochondria; Optic Lobe, Nonmammalian; Proline; Retina | 1976 |
Patterns of inter- and intralaminar GABAergic connections distinguish striate (V1) and extrastriate (V2, V4) visual cortices and their functionally specialized subdivisions in the rhesus monkey.
Topics: Animals; Autoradiography; Electron Transport Complex IV; gamma-Aminobutyric Acid; Macaca mulatta; Microinjections; Neural Pathways; Neurons; Nipecotic Acids; Proline; Tritium; Visual Cortex | 1992 |
Postsynaptic action of endogenous GABA released by nipecotic acid in the hippocampus.
Topics: Animals; Carrier Proteins; Electrodes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Nipecotic Acids; Organophosphorus Compounds; Picrotoxin; Proline; Pyramidal Tracts; Rats; Synapses; Tetrodotoxin | 1992 |
Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurons; Nipecotic Acids; Proline; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tiagabine | 1992 |
Transient presence and functional interaction of endogenous GABA and GABAA receptors in developing rat optic nerve.
Topics: Action Potentials; Animals; Animals, Newborn; gamma-Aminobutyric Acid; Immunohistochemistry; Membrane Potentials; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Regionally selective deficits in uptake sites for glutamate and gamma-aminobutyric acid in the basal ganglia in schizophrenia.
Topics: Aspartic Acid; Brain; Caudate Nucleus; Dominance, Cerebral; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glutamic Acid; Humans; Nipecotic Acids; Nucleus Accumbens; Proline; Putamen; Radioligand Assay; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology | 1992 |
The effects of gamma-aminobutyric acid on voltage-clamped motoneurons of the lobster cardiac ganglion.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Ganglia; Membrane Potentials; Motor Neurons; Nephropidae; Nipecotic Acids; Picrotoxin; Proline; Receptors, GABA-A; Sodium | 1992 |
Neurochemical evidence for a neuronal GABAergic system in the rat sympathetic superior cervical ganglion.
Topics: Acetanilides; Anesthetics, Local; Animals; beta-Alanine; Brain Chemistry; Calcium; Female; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Kinetics; Male; Neurons; Neurotransmitter Agents; Nipecotic Acids; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Veratrine | 1992 |
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
Topics: Administration, Oral; Animals; Anticonvulsants; Benzhydryl Compounds; Blood-Brain Barrier; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Mice; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Structure-Activity Relationship | 1992 |
Selective retrograde transport of nipecotic acid, a GABA analog, labels a subpopulation of gerbil olivocochlear neurons.
Topics: Animals; Autoradiography; Biological Transport; Cochlea; gamma-Aminobutyric Acid; Gerbillinae; Horseradish Peroxidase; Microscopy, Electron; Neural Pathways; Neurons, Efferent; Nipecotic Acids; Olivary Nucleus; Perfusion; Proline; Sensitivity and Specificity; Tritium | 1992 |
Effect of amygdala kindling on the in vivo release of GABA and 5-HT in the dorsal raphe nucleus in freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Dialysis; Fluoxetine; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Nipecotic Acids; Potassium; Proline; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin; Veratridine | 1992 |
Co-release of acetylcholine and GABA by the starburst amacrine cells.
Topics: Acetylcholine; Animals; Autoradiography; Drug Carriers; GABA Antagonists; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Retina | 1992 |
Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA.
Topics: Action Potentials; Animals; Baclofen; Cobalt; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neurons; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Vestibular Nuclei | 1992 |
Changes in extracellular K+ evoked by GABA, THIP and baclofen in the guinea-pig hippocampal slice.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electrodes; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoxazoles; Nipecotic Acids; Potassium; Proline; Receptors, GABA-A; Temperature | 1991 |
Age-dependent extrasynaptic modulation of axonal conduction by exogenous and endogenous GABA in the rat optic nerve.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Axons; Cells, Cultured; gamma-Aminobutyric Acid; Isonicotinic Acids; Neural Conduction; Nipecotic Acids; Optic Nerve; Proline; Rats; Receptors, GABA-A; Synapses | 1991 |
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cerebellum; Chlorides; Cyclic GMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Lithium; Lithium Chloride; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nipecotic Acids; Nitroprusside; Organic Anion Transporters; Proline; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Secretory Rate; Sodium; Stimulation, Chemical | 1991 |
High sensitivity HPLC assay for GABA in brain dialysis studies.
Topics: Acetonitriles; Amino Acids; Amino Acids, Neutral; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Microchemistry; Nipecotic Acids; Oxidation-Reduction; Proline; Rats | 1991 |
Presence of a highly efficient "binding" to bacterial contamination can distort data from binding studies.
Topics: Animals; Cats; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Gram-Positive Bacteria; Isonicotinic Acids; Muscimol; Nipecotic Acids; Proline; Pyridazines; Radioligand Assay; Receptors, GABA-A; Tritium | 1990 |
Calcium-independent gamma-aminobutyric acid release from growth cones: role of gamma-aminobutyric acid transport.
Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Membrane; Diencephalon; Female; gamma-Aminobutyric Acid; Male; Neurons; Nipecotic Acids; Potassium; Proline; Rats; Rats, Inbred Strains; Synaptosomes; Telencephalon | 1991 |
Cholinergic nerve terminals of human cerebral cortex possess a GABA transporter whose activation induces release of acetylcholine.
Topics: Acetylcholine; Anticonvulsants; Baclofen; Bicuculline; Biotransformation; Carrier Proteins; Cerebral Cortex; Choline; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Muscimol; Nerve Endings; Nerve Tissue Proteins; Nipecotic Acids; Organic Anion Transporters; Parasympathetic Nervous System; Proline; Synaptosomes | 1991 |
[3H]nipecotic acid binding to gamma-aminobutyric acid uptake sites in postmortem human brain.
Topics: Aged; Aging; Binding Sites; Brain; Cadaver; Female; gamma-Aminobutyric Acid; Hippocampus; Humans; Huntington Disease; Male; Middle Aged; Nipecotic Acids; Postmortem Changes; Proline; Sodium; Tritium | 1990 |
GABA agonists and uptake inhibitors. Synthesis, absolute stereochemistry, and enantioselectivity of (R)-(-)- and (S)-(+)-homo-beta-proline.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hydrogen Bonding; Male; Molecular Conformation; Molecular Structure; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes; Synaptosomes; X-Ray Diffraction | 1990 |
Studies on the mechanism of interactions between anesthetic steroids and gamma-aminobutyric acidA receptors.
Topics: Anesthetics; Animals; Chlorides; Desoxycorticosterone; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Nipecotic Acids; Pentobarbital; Pregnanolone; Progesterone; Proline; Rats; Receptors, GABA-A; Synaptic Membranes | 1990 |
Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia.
Topics: Aged; Aged, 80 and over; Amygdala; Dominance, Cerebral; Dopamine; Female; gamma-Aminobutyric Acid; Hippocampus; Humans; Male; Middle Aged; Nipecotic Acids; Proline; Receptors, Dopamine; Receptors, GABA-A; Schizophrenia; Schizophrenic Psychology; Temporal Lobe | 1990 |
A novel mechanism for oxidative cleavage of prolyl peptides induced by the hydroxyl radical.
Topics: Collagen; Free Radicals; gamma-Aminobutyric Acid; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Peptides; Proline | 1990 |
Na(+)-dependent GABA transport system scavenges endogenous external GABA and prevents desensitization of GABAA receptors in rat cerebrocortical synaptoneurosomes.
Topics: Animals; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Muscimol; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium; Synaptosomes | 1990 |
Endogenous GABA acts on GABAB receptors in nucleus tractus solitarius to increase blood pressure.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vigabatrin | 1990 |
Effects of gamma-aminobutyric acid on skate retinal horizontal cells: evidence for an electrogenic uptake mechanism.
Topics: Animals; Bicuculline; Biological Transport, Active; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Picrotoxin; Proline; Retina; Skates, Fish; Sodium | 1990 |
Endogenous GABA mediates presynaptic inhibition of spontaneous and evoked excitatory synaptic potentials in the rat neostriatum.
Topics: Animals; Baclofen; Corpus Striatum; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1990 |
Effect of local inhibition of gamma-aminobutyric acid uptake in the dorsomedial hypothalamus on extracellular levels of gamma-aminobutyric acid and on stress-induced tachycardia: a study using microdialysis.
Topics: Amino Acids; Animals; Blood Pressure; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Nipecotic Acids; Potassium; Proline; Rats; Rats, Inbred Strains; Stress, Physiological; Tachycardia | 1990 |
Alcohol and GABA: ethanol intake modifies hippocampal nipecotic acid binding in ethanol-preferring and non-preferring rats.
Topics: Animals; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Proline; Rats; Self Administration | 1990 |
Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Male; Models, Biological; Neurons; Nipecotic Acids; Pentobarbital; Proline; Rats; Rats, Inbred Strains; Synapses | 1985 |
gamma-Aminobutyric acid antagonists stimulate vasopressin release from organ-cultured hypothalamo-neurohypophyseal explants.
Topics: Acetylcholine; Animals; Bacitracin; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Ion Channels; Male; Nipecotic Acids; Organ Culture Techniques; Osmolar Concentration; Penicillins; Picrotoxin; Pituitary Gland, Posterior; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
Depolarization without calcium can release gamma-aminobutyric acid from a retinal neuron.
Topics: Animals; Benzofurans; Calcium; Catfishes; Cell Communication; Cell Membrane; Cells, Cultured; Chlorides; Egtazic Acid; Electrophysiology; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Ion Channels; Neurons; Nipecotic Acids; Photoreceptor Cells; Proline; Retina; Synapses | 1987 |
Maitotoxin-evoked gamma-aminobutyric acid release is due not only to the opening of calcium channels.
Topics: Amino Acids; Animals; Calcium; Cells, Cultured; Cobalt; Corpus Striatum; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Marine Toxins; Mice; Neurons; Nifedipine; Nipecotic Acids; Oxocins; Proline; Sodium; Tetrodotoxin | 1988 |
Presynaptic mechanisms underlying the gamma-aminobutyric acid-evoked receptor-independent release of [3H]norepinephrine in rat hippocampus.
Topics: Animals; Biomechanical Phenomena; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Sodium; Synapses; Tetrodotoxin; Tritium | 1989 |
Cardiovascular responses elicited by gamma-aminobutyric acid in the nucleus tractus solitarius: evidence for action at the GABAB receptor.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Hemodynamics; Injections; Male; Medulla Oblongata; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vasopressins | 1989 |
The effect of GABA on neurotransmission in frog tectal slices.
Topics: Action Potentials; Animals; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Nipecotic Acids; Proline; Rana catesbeiana; Superior Colliculi; Synaptic Transmission | 1989 |
Entropy as a factor in the binding of gamma-aminobutyric acid and nipecotic acid to the gamma-aminobutyric acid transport system.
Topics: Animals; Binding Sites; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Molecular Conformation; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Temperature; Thermodynamics | 1989 |
Further evidence for the GABAergic influence on memory. Interaction of GABAergic transmission with angiotensin II on memory processes.
Topics: Angiotensin II; Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
The motor response to ethylenediamine of the rat isolated duodenum: involvement of GABAergic transmission?
Topics: 3-Mercaptopropionic Acid; Animals; Benzalkonium Compounds; Duodenum; Ethylenediamines; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Tetrodotoxin | 1989 |
Reduced GABA uptake sites in the temporal lobe in schizophrenia.
Topics: Amygdala; Cerebral Cortex; Functional Laterality; gamma-Aminobutyric Acid; Hippocampus; Humans; Middle Aged; Nipecotic Acids; Proline; Schizophrenia; Temporal Lobe | 1989 |
Multiple components of synaptosomal [3H]-gamma-aminobutyric acid release resolved by a rapid superfusion system.
Topics: Animals; Brain; Cadmium; Calcium; gamma-Aminobutyric Acid; Kinetics; Male; Nickel; Nipecotic Acids; Proline; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Tritium | 1989 |
Rhythmical bursting activity and GABAergic mechanisms in the medial septum of normal and pertussis toxin-pretreated rats.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Male; Neurons; Nipecotic Acids; Pertussis Toxin; Proline; Rats; Rats, Inbred Strains; Septum Pellucidum; Virulence Factors, Bordetella | 1989 |
Evidence of an endogenous forebrain GABAergic system capable of inhibiting baroreceptor-mediated vasopressin release.
Topics: Animals; Arginine Vasopressin; Frontal Lobe; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Loss of cortical GABA uptake sites in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Proline; Receptors, GABA-A | 1988 |
Excitatory and inhibitory action of GABA on synaptic transmission in slices of guinea pig superior colliculus.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Nipecotic Acids; Perfusion; Proline; Receptors, GABA-A; Superior Colliculi; Synaptic Membranes; Synaptic Transmission | 1988 |
Electrophysiological evidence that nipecotic acid can be used in vivo as a false transmitter.
Topics: Animals; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Inhibition of GABA uptake potentiates the effects of exogenous GABA on locust skeletal muscle.
Topics: Aminobutyrates; Animals; beta-Alanine; Female; GABA Antagonists; gamma-Aminobutyric Acid; Grasshoppers; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscles; Nipecotic Acids; Proline | 1985 |
Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Ethanolamine; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Parkinson Disease; Proline; Tremor | 1987 |
Effect of taurine on neurotransmitter release from insect synaptosomes.
Topics: Acetylcholine; Animals; Choline; gamma-Aminobutyric Acid; Grasshoppers; Neurotransmitter Agents; Nipecotic Acids; Potassium; Proline; Synaptosomes; Taurine; Veratridine | 1988 |
Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture.
Topics: Amino Acids; Animals; Biomechanical Phenomena; Calcium; Cells, Cultured; Chlorides; Corpus Striatum; Fetus; gamma-Aminobutyric Acid; Lithium; Mice; Mice, Inbred Strains; Neuroglia; Neurons; Nipecotic Acids; Proline; Second Messenger Systems; Tetanus Toxin; Veratridine | 1989 |
Inhibition of intrathecally administered picrotoxin- and bicuculline-induced convulsions in mice by pipecolic acid or GABA.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Nipecotic Acids; Picrotoxin; Pipecolic Acids; Proline; Receptors, GABA-A; Seizures; Strychnine | 1985 |
Retrograde labeling of dorsal root ganglion neurons after injection of tritiated amino acids in the spinal cord of rats and cats.
Topics: Amino Acids; Animals; Aspartic Acid; Autoradiography; Biological Transport; Cats; gamma-Aminobutyric Acid; Ganglia, Spinal; Proline; Rats; Spinal Cord; Synaptic Transmission | 1985 |
Nipecotic acid, an uptake blocker, prevents fading of the gamma-aminobutyric acid effect.
Topics: Animals; Drug Synergism; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin | 1986 |
Uptake of GABA and nipecotic acid in astrocytes and neurons in primary cultures: changes in the sodium coupling ratio during differentiation.
Topics: Animals; Astrocytes; Biological Transport; Bucladesine; Cell Differentiation; Cells, Cultured; gamma-Aminobutyric Acid; Kinetics; Mathematics; Mice; Neurons; Nipecotic Acids; Proline; Sodium | 1986 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Gamma-aminobutyric acid and the high pressure neurological syndrome.
Topics: Alanine; Aminobutyrates; Animals; Atmospheric Pressure; Central Nervous System Diseases; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; High Pressure Neurological Syndrome; Male; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Tremor; Valproic Acid | 1986 |
Effect of ethanol on GABA uptake and release from hypothalamic fragments.
Topics: Animals; Calcium; Ethanol; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Male; Nipecotic Acids; Potassium; Proline; Radioligand Assay; Rats; Rats, Inbred Strains | 1988 |
Enhanced pressor response to GABA in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Topics: Animals; Baclofen; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Male; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Characterization of [3H]GABA release from striatal slices: evidence for a calcium-independent process via the GABA uptake system.
Topics: Animals; Calcium; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Tetrodotoxin | 1988 |
Kinetic characterization of inhibition of gamma-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine.
Topics: Animals; Anticonvulsants; Astrocytes; Cells, Cultured; Cerebral Cortex; Chemical Phenomena; Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Neurons; Nicotinic Acids; Nipecotic Acids; Proline | 1988 |
Fast HPLC estimation of gamma-aminobutyric acid in microdialysis perfusates: effect of nipecotic and 3-mercaptopropionic acids.
Topics: 3-Mercaptopropionic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1988 |
Studies on GABAergic mechanisms responsible for cardiovascular regulation in the rostral ventrolateral medulla of the rat.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; gamma-Aminobutyric Acid; Hemodynamics; Male; Medulla Oblongata; Microinjections; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Inbred Strains; Veratrine | 1987 |
Mechanisms of endogenous GABA release from hypothalamic fragments. Effect of prolactin.
Topics: 3-Mercaptopropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Culture Techniques; gamma-Aminobutyric Acid; Hypothalamus; Male; Median Eminence; Nipecotic Acids; Paraventricular Hypothalamic Nucleus; Potassium; Prolactin; Proline; Rats; Rats, Inbred Strains | 1987 |
Autoradiographic study of the distribution of [3H]gamma-aminobutyrate-accumulating neural elements in guinea-pig intestine: evidence for a transmitter function of gamma-aminobutyrate.
Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Aminobutyrates; Animals; Autoradiography; Colon; Cyclohexanecarboxylic Acids; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Leucine; Male; Myenteric Plexus; Neurons; Nipecotic Acids; Paraffin; Proline | 1986 |
Nipecotic acid: preferential accumulation in the cochlea by GABA uptake systems and selective retrograde transport to brainstem.
Topics: Animals; Autoradiography; Biological Transport, Active; Brain Stem; Cochlea; Efferent Pathways; gamma-Aminobutyric Acid; Gerbillinae; Neurons, Efferent; Nipecotic Acids; Olivary Nucleus; Proline; Time Factors | 1986 |
GABAergic mechanisms in nucleus tractus solitarius alter blood pressure and vasopressin release.
Topics: Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
Factors controlling the release of GABA from goldfish retinal horizontal cells.
Topics: Animals; Calcium; Cyprinidae; Dopamine; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Light; Mitochondria; Neurons; Nipecotic Acids; Proline; Retina; Sodium | 1985 |
Uptake of gamma-aminobutyric acid by human blood platelets: comparison with CNS uptake.
Topics: Amino Acids; Amino Acids, Cyclic; beta-Alanine; Blood Platelets; Central Nervous System; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Humans; Kinetics; Nipecotic Acids; Proline; Sodium; Taurine | 1985 |
Uptake of GABA by bovine adrenal medulla slices.
Topics: Adrenal Medulla; Aminobutyrates; Animals; beta-Alanine; Cattle; gamma-Aminobutyric Acid; Glucose; Kinetics; Nipecotic Acids; Potassium; Proline; Sodium; Time Factors | 1985 |
Release of previously incorporated gamma-[3H]aminobutyric acid in rabbit caudate nucleus slices.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Calcium; Caudate Nucleus; Cyclohexanecarboxylic Acids; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Proline; Rabbits; Tetrodotoxin; Tritium | 1986 |
Release of purines, noradrenaline, and GABA from rat hippocampal slices by field stimulation.
Topics: Adenine; Aminooxyacetic Acid; Animals; Dipyridamole; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Norepinephrine; Potassium; Proline; Purines; Rats; Rats, Inbred Strains | 1985 |
GABAergic inhibition of hypertonic saline-induced vasopressin-dependent hypertension.
Topics: Aminobutyrates; Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Male; Nephrectomy; Nipecotic Acids; Osmolar Concentration; Proline; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sodium; Sympathetic Nervous System; Vasopressins | 1985 |
Identification and characterization of pipecolic acid binding sites in mouse brain.
Topics: Aging; Animals; Binding Sites; Brain; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pipecolic Acids; Proline; Sodium; Sodium Chloride; Tissue Distribution | 1985 |
Role of uptake in gamma-aminobutyric acid (GABA)-mediated responses in guinea pig hippocampal neurons.
Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Iontophoresis; Male; Membrane Potentials; Neural Inhibition; Neurons; Nipecotic Acids; Proline; Synapses | 1985 |
Amino acid and serotonin content in the nervous system, muscle and blood of the cockroach Periplaneta americana.
Topics: Amino Acids; Animals; Autoradiography; Carbon Radioisotopes; Chromatography; Cockroaches; Dinitrophenols; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glycine; Muscles; Ouabain; Proline; Serotonin; Strychnine; Temperature; Time Factors | 1974 |
Effects of gamma-aminobutyric acid (GABA) and GABA antagonist drugs on ACTH release.
Topics: Adrenocorticotropic Hormone; Alkaloids; Aminobutyrates; Animals; Corticosterone; Dioxoles; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hypothalamus; Interneurons; Isoquinolines; Male; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Picrotoxin; Pituitary Gland; Pituitary Gland, Anterior; Proline; Rats; Sodium Chloride; Stimulation, Chemical; Synaptic Transmission | 1974 |
The time course of GABA action on the crayfish stretch receptor: evidence for a saturable GABA uptake.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Mechanoreceptors; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Nipecotic Acids; Proline; Receptors, Cell Surface; Receptors, GABA-A; Synapses; Synaptic Transmission; Vas Deferens | 1984 |
Chronic antidepressants and GABA "B" receptors: a GABA hypothesis of antidepressant drug action.
Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Desipramine; Frontal Lobe; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Pargyline; Proline; Propylamines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Viloxazine | 1984 |
Release of neurotransmitter amino acids from synaptosomes: enhancement of calcium-independent efflux by oleic and arachidonic acids.
Topics: Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Neurotransmitter Agents; Oleic Acid; Oleic Acids; Proline; Rats; Rats, Inbred Strains; Synaptosomes; Veratridine | 1983 |
Selective inhibition of synaptosomal proline uptake by leucine and methionine enkephalins.
Topics: Animals; Aspartic Acid; Biological Transport; Cerebral Cortex; Enkephalin, Leucine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Neurotransmitter Agents; Proline; Rats; Rats, Inbred Strains; Synaptosomes; Taurine | 1983 |
Arginine metabolism in mouse brain synaptosomes.
Topics: Animals; Arginine; Biological Transport; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Mice; Ornithine; Proline; Synaptosomes | 1984 |
[Degradation of glutamic acid and proline in Clostridium sordellii under cadaveric bacteriological inspection].
Topics: Amino Acids; Amino Acids, Neutral; Brain; Cadaver; Clostridium; Culture Media; Decarboxylation; Forensic Medicine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Postmortem Changes; Proline; Temperature | 1984 |
GABAB receptor-mediated inhibition of serotonin release in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Nipecotic Acids; Phentolamine; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin | 1984 |
Inhibition of GABA uptake potentiates the conductance increase produced by GABA-mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea-pig.
Topics: Animals; Central Nervous System; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isonicotinic Acids; Muscimol; Neural Conduction; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Olfactory Pathways; Proline; Sodium; Taurine | 1984 |
Effect of homo-beta-proline and other heterocyclic GABA analogues on GABA uptake in neurons and astroglial cells and on GABA receptor binding.
Topics: Animals; Animals, Newborn; Astrocytes; Biological Transport; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred Strains; Neurons; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1981 |
GABA as a trophic factor during development.
Topics: Animals; Animals, Newborn; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Nipecotic Acids; Proline; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina | 1983 |
Synaptic interactions in the GABA system during postnatal development in retina.
Topics: Animals; Cell Differentiation; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Proline; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission | 1983 |
Comparison of GABA analogues at the crayfish stretch receptor neurone.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Isoxazoles; Mechanoreceptors; Membrane Potentials; Muscimol; Nipecotic Acids; Proline; Sodium | 1983 |
Study of the mechanism of release of [3H]GABA from a teleost retina in vitro.
Topics: Alanine; Animals; Calcium; Calcium Channel Blockers; Fishes; gamma-Aminobutyric Acid; Nipecotic Acids; Potassium; Proline; Retina; Sodium; Tetrodotoxin; Veratridine | 1984 |
Quantification by selected ion monitoring of pipecolic acid, proline, gamma-aminobutyric acid and glycine in rat brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glycine; Male; Pipecolic Acids; Proline; Rats; Rats, Inbred Strains | 1984 |
Kinetic analysis of the accumulation of gamma-aminobutyric acid by particulate fractions of rat brain: comparison of the effects of nipecotic acid and cis-3-aminocyclohexane-1-carboxylic acid.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Kinetics; Male; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Tritium | 1983 |
Ketamine potentiates the responses of the rat superior cervical ganglion to GABA.
Topics: Animals; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ketamine; Male; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Taurine | 1984 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
Synaptosomal [3H]GABA uptake and [3H]nipecotic acid binding in audiogenic seizure susceptible (DBA/2) and resistant (C57 B1/6) mice.
Topics: Acoustic Stimulation; Age Factors; Animals; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nipecotic Acids; Pons; Proline; Seizures; Synaptosomes | 1984 |
In vivo effects of nipecotic acid on levels of extracellular GABA and taurine, and hippocampal excitability.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Taurine | 1984 |
Efflux and exchange of gamma-aminobutyric acid and nipecotic acid catalysed by synaptic plasma membrane vesicles isolated from immature rat brain.
Topics: Animals; Brain; Chlorides; Female; gamma-Aminobutyric Acid; Kinetics; Nigericin; Nipecotic Acids; Proline; Rats; Sodium; Synaptic Membranes | 1983 |
Ion dependency of uptake and release of GABA and (RS)-nipecotic acid studied in cultured mouse brain cortex neurons.
Topics: Animals; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Mice; Neurons; Nipecotic Acids; Proline; Sodium | 1983 |
A possible rôle for acid phosphatase in gamma-amino-n-butyrate uptake in Aspergillus nidulans.
Topics: Acid Phosphatase; Alanine; Aspergillus nidulans; gamma-Aminobutyric Acid; Membrane Transport Proteins; Mutation; Proline; Pyrrolidinones; Pyrroline Carboxylate Reductases | 1980 |
Effect of nipecotic acid, a gamma-aminobutyric acid transport inhibitor, on the turnover and release of gamma-aminobutyric acid in rat cortical slices.
Topics: Animals; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Magnesium; Nipecotic Acids; Potassium; Proline; Rats; Tetrodotoxin; Tritium | 1982 |
Comparison of synaptosomal and glial uptake of pipecolic acid and GABA in rat brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neuroglia; Nipecotic Acids; Pipecolic Acids; Potassium; Proline; Rats; Synaptosomes | 1981 |
[Nipecotic acid, a competitive inhibitor of the net uptake of 3H-GABA by rat brain synaptosomes].
Topics: Absorption; Animals; Cerebral Cortex; Depression, Chemical; gamma-Aminobutyric Acid; In Vitro Techniques; Nipecotic Acids; Proline; Rats; Synaptosomes | 1981 |
Comparison between (RS)-nipecotic acid and GABA transport in cultured astrocytes: coupling with two sodium ions.
Topics: Animals; Astrocytes; Biological Transport; gamma-Aminobutyric Acid; Kinetics; Mice; Nipecotic Acids; Proline; Sodium | 1981 |
L-proline as a glutamate antagonist at a crustacean neuromuscular junction.
Topics: Animals; Astacoidea; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Isoleucine; Mathematics; Muscle Contraction; Neuromuscular Junction; Picrotoxin; Proline | 1980 |
Actions of nipecotic acid and SKF89976A on GABA transporter in cone-driven horizontal cells dissociated from the catfish retina.
Topics: Animals; Anticonvulsants; Carrier Proteins; Catfishes; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Patch-Clamp Techniques; Proline; Retina | 1995 |
GABA-mediated inhibition of the anaphylactic response in the guinea-pig trachea.
Topics: Anaphylaxis; Animals; beta-Alanine; Bronchial Hyperreactivity; Capsaicin; Drug Interactions; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine Release; Macrophage Activation; Macrophages, Alveolar; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Nipecotic Acids; Ovalbumin; Platelet Activating Factor; Proline; Receptors, GABA; Tetrodotoxin; Trachea | 1995 |
Pyridine carboxylic acids as inhibitors and substrates of the Escherichia coli gab permease encoded by gabP.
Topics: Biological Transport; Escherichia coli; Escherichia coli Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Genes, Bacterial; Membrane Transport Modulators; Membrane Transport Proteins; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Piperidines; Proline; Substrate Specificity | 1995 |
Cloning, functional expression, and pharmacology of a GABA transporter from Manduca sexta.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; DNA Primers; Embryo, Nonmammalian; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Gene Library; Kinetics; Manduca; Membrane Proteins; Membrane Transport Proteins; Mice; Molecular Sequence Data; Nipecotic Acids; Oocytes; Organic Anion Transporters; Polymerase Chain Reaction; Proline; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis | 1995 |
Effects of thiopental, halothane and isoflurane on the calcium-dependent and -independent release of GABA from striatal synaptosomes in the rat.
Topics: Anesthetics; Animals; Calcium; Corpus Striatum; gamma-Aminobutyric Acid; Halothane; Isoflurane; Male; Membrane Potentials; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Synaptosomes; Thiopental; Veratridine | 1995 |
Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Synergism; Electric Conductivity; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Patch-Clamp Techniques; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes.
Topics: Anesthetics; Animals; Biological Transport; Clonidine; Corpus Striatum; Enflurane; Etomidate; gamma-Aminobutyric Acid; Halothane; In Vitro Techniques; Isoflurane; Ketamine; Male; Nipecotic Acids; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Synaptosomes; Thiopental | 1995 |
An investigation of the origin of extracellular GABA in rat nucleus accumbens measured in vivo by microdialysis.
Topics: 3-Mercaptopropionic Acid; Animals; Calcium; Chromatography, High Pressure Liquid; Electrochemistry; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Magnesium; Male; Microdialysis; Nipecotic Acids; Nucleus Accumbens; Potassium; Proline; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1994 |
Progressive decrease in extracellular GABA concentrations in the post-ischemic period in the striatum: a microdialysis study.
Topics: Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Extracellular Space; gamma-Aminobutyric Acid; Gerbillinae; Glutamic Acid; Microdialysis; Neostriatum; Nipecotic Acids; Proline; Substantia Nigra | 1994 |
The URE2 protein regulates nitrogen catabolic gene expression through the GATAA-containing UASNTR element in Saccharomyces cerevisiae.
Topics: Allantoin; Amino Acids; Base Sequence; Biological Transport; Fungal Proteins; gamma-Aminobutyric Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Reporter; Glutathione Peroxidase; Molecular Sequence Data; Nitrogen; Prions; Proline; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription, Genetic | 1994 |
Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve.
Topics: Acetates; Action Potentials; Amines; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; GABA-A Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Depolarizing Agents; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.
Topics: Animals; Binding Sites; Biological Transport; Blood-Brain Barrier; Carrier Proteins; Cell Line; Cloning, Molecular; Drug Design; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Proline; Rats | 1994 |
Phorbol ester-induced inhibition of GABA uptake by synaptosomes and by Xenopus oocytes expressing GABA transporter (GAT1).
Topics: Alkaloids; Animals; Base Sequence; Brain; Carrier Proteins; Cerebral Cortex; DNA, Complementary; Female; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Library; Kinetics; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Nipecotic Acids; Oligonucleotide Probes; Oocytes; Organic Anion Transporters; Proline; Protein Kinase C; Rats; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate; Xenopus | 1994 |
Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents.
Topics: Animals; Brain Tissue Transplantation; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Female; Fetal Tissue Transplantation; gamma-Aminobutyric Acid; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Neurons, Afferent; Nipecotic Acids; Oxidopamine; Potassium Chloride; Proline; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Tyrosine 3-Monooxygenase | 1993 |
Specificity of the imino acid carrier in rat small intestine.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carrier Proteins; gamma-Aminobutyric Acid; Imino Acids; Intestine, Small; Male; Microvilli; Proline; Rats; Species Specificity; Taurine | 1994 |
Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat.
Topics: Animals; Autoradiography; Brain Ischemia; Brain Tissue Transplantation; Cell Transplantation; Cerebral Arteries; Cerebral Infarction; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Learning; Male; Microdialysis; Neostriatum; Nipecotic Acids; Proline; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
Non-synaptic modulation of dorsal column conduction by endogenous GABA in neonatal rat spinal cord.
Topics: Action Potentials; Animals; Animals, Newborn; Axons; gamma-Aminobutyric Acid; Neural Conduction; Nipecotic Acids; Proline; Rats; Receptors, GABA-A; Spinal Cord; Synapses | 1993 |
Genes required for GABA function in Caenorhabditis elegans.
Topics: Animals; Behavior, Animal; Caenorhabditis elegans; Cell Differentiation; gamma-Aminobutyric Acid; Genes, Helminth; Muscimol; Mutation; Neurons; Nipecotic Acids; Proline | 1993 |
Extracellular gamma-aminobutyric acid levels in the rat caudate-putamen: monitoring the neuronal and glial contribution by intracerebral microdialysis.
Topics: Animals; Calcium; Caudate Nucleus; Chromatography, High Pressure Liquid; Dialysis; Electrochemistry; Extracellular Space; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Neuroglia; Neurons; Nipecotic Acids; Potassium Chloride; Proline; Putamen; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Veratridine | 1993 |
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve.
Topics: Action Potentials; Aging; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Myelin Sheath; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Mutant Strains; Receptors, GABA-A; Reference Values | 1993 |
The spinal GABA system modulates burst frequency and intersegmental coordination in the lamprey: differential effects of GABAA and GABAB receptors.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Diazepam; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Lampreys; Locomotion; Motor Neurons; Muscimol; Muscles; N-Methylaspartate; Nerve Net; Neurons; Nipecotic Acids; Proline; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1993 |
The effects of lowered extracellular sodium on gamma-aminobutyric acid (GABA)-induced currents of Muller (glial) cells of the skate retina.
Topics: Animals; Cells, Cultured; Chloride Channels; Extracellular Space; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Membrane Proteins; Neuroglia; Nipecotic Acids; Proline; Receptors, GABA-A; Signal Transduction; Skates, Fish; Sodium | 1993 |
Regulatory circuit for responses of nitrogen catabolic gene expression to the GLN3 and DAL80 proteins and nitrogen catabolite repression in Saccharomyces cerevisiae.
Topics: Allantoin; Asparagine; Base Sequence; DNA-Binding Proteins; Fungal Proteins; gamma-Aminobutyric Acid; GATA Transcription Factors; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Glutamine; Models, Genetic; Molecular Sequence Data; Nitrogen; Proline; Regulatory Sequences, Nucleic Acid; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 1993 |
Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Alanine; Betaine; Biological Transport; Brain; Brain Chemistry; Carrier Proteins; Cloning, Molecular; DNA; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Mice; Molecular Sequence Data; Nipecotic Acids; Oocytes; Organ Specificity; Organic Anion Transporters; Proline; RNA, Messenger; Taurine; Xenopus | 1993 |
Characterization of the nipecotic binding to rat brain membranes.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate.
Topics: Animals; Anticonvulsants; GABA Antagonists; gamma-Aminobutyric Acid; Molecular Structure; Nicotinic Acids; Nipecotic Acids; Proline; Prosencephalon; Rats; Stereoisomerism; Structure-Activity Relationship; Synaptosomes; Tiagabine | 1993 |
The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophysiology; Extracellular Space; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Microinjections; Nipecotic Acids; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Effect of catecholestrogens on [3H]-GABA uptake by hypothalamic crude synaptosomes.
Topics: Animals; Estradiol; Estrogens, Catechol; Estrone; Female; gamma-Aminobutyric Acid; Hydroxyestrones; Hypothalamus; In Vitro Techniques; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium | 1995 |
GABA concentrations in the striatum following repetitive cerebral ischemia.
Topics: Animals; Corpus Striatum; Drug Synergism; gamma-Aminobutyric Acid; Gerbillinae; Ischemic Attack, Transient; Male; Membrane Potentials; Microdialysis; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Potassium Chloride; Proline; Recurrence | 1995 |
Endogenous GABA modulates histamine release from the anterior hypothalamus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Histamine Release; Hypothalamus, Anterior; Male; Microdialysis; Neurons; Nipecotic Acids; Picrotoxin; Presynaptic Terminals; Proline; Rats; Rats, Wistar | 1996 |
Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2.
Topics: Analgesics; Animals; Benzoxazines; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Globus Pallidus; Male; Morpholines; Naphthalenes; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Entorhinal Cortex; Epilepsy; Female; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Wistar; Tiagabine | 1996 |
Nitric oxide-evoked [3H] gamma-aminobutyric acid release is mediated by two distinct release mechanisms.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Neurons; Nipecotic Acids; Nitric Oxide; Nitroprusside; Oximes; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine; Sodium; Tritium | 1996 |
GABAA receptor-mediated K(+)-evoked GABA release from globus pallidus--analysis using microdialysis.
Topics: Animals; Baclofen; Dinucleoside Phosphates; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Muscimol; Nipecotic Acids; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
In vivo characterization of extracellular GABA release in the caudate nucleus and prefrontal cortex of the rhesus monkey.
Topics: Animals; Calcium; Caudate Nucleus; Cerebrospinal Fluid; GABA Agents; gamma-Aminobutyric Acid; Infusions, Parenteral; Macaca mulatta; Membrane Potentials; Microdialysis; Nipecotic Acids; Potassium; Prefrontal Cortex; Proline; Tetrodotoxin; Veratridine | 1997 |
1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter.
Topics: Animals; Carrier Proteins; Cell Line; Cricetinae; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Mice; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Organic Anion Transporters; Piperidines; Proline; Tiagabine | 1997 |
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
Topics: Animals; Baclofen; Eating; Enzyme Inhibitors; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Nucleus Accumbens; Proline; Rats; Rats, Sprague-Dawley; Vigabatrin | 1997 |
Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular gamma-aminobutyrate levels in rat thalamus.
Topics: Animals; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Extracellular Space; gamma-Aminobutyric Acid; Isoxazoles; Microdialysis; Nipecotic Acids; Proline; Rats; Rats, Wistar; Thalamus | 1997 |
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniques; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycolysis; Iodoacetates; Ischemia; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Retina | 1997 |
Vigabatrin enhances promoted release of GABA in neonatal rat optic nerve.
Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Axons; Bicuculline; Carrier Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Models, Neurological; Nipecotic Acids; Optic Nerve; Organic Anion Transporters; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Time Factors; Vigabatrin | 1998 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium; High Pressure Neurological Syndrome; Male; Motor Activity; Muscimol; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra; Synaptic Transmission; Time Factors; Vigabatrin | 1998 |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions.
Topics: Amino Acid Transport Systems, Neutral; Cell Division; Culture Media; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation, Fungal; Hydrogen-Ion Concentration; Membrane Transport Proteins; Mutation; Organic Anion Transporters; Proline; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcriptional Activation | 1998 |
Amphetamine releases GABA in striatum of the freely moving rat: involvement of calcium and high affinity transporter mechanisms.
Topics: Amphetamine; Animals; Calcium; Carrier Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Membrane Proteins; Membrane Transport Proteins; Microdialysis; Neostriatum; Nipecotic Acids; Organic Anion Transporters; Proline; Rats; Rats, Wistar | 1998 |
Evidence for a contribution of lateral inhibition to orientation tuning and direction selectivity in cat visual cortex: reversible inactivation of functionally characterized sites combined with neuroanatomical tracing techniques.
Topics: Animals; Cats; Functional Laterality; gamma-Aminobutyric Acid; Iontophoresis; Lysine; Neural Inhibition; Neurons; Nipecotic Acids; Orientation; Proline; Synaptic Transmission; Visual Cortex | 1998 |
GABA excites immature CA3 pyramidal cells through bicuculline-sensitive and -insensitive chloride-dependent receptors.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Chloride Channels; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Kynurenic Acid; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Proline; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, GABA-B; Zinc | 1998 |
Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.
Topics: Aminobutyrates; Anesthesia, General; Anesthetics, Intravenous; Animals; Baclofen; Bicuculline; Calcium; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Synaptic Transmission; Synaptosomes; Tritium | 1998 |
Inhibitors of gamma-aminobutyric acid transport as experimental tools and therapeutic agents.
Topics: Animals; Brain; Carrier Proteins; Cloning, Molecular; Drug Design; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Molecular Structure; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Organic Anion Transporters; Proline; Radioligand Assay; Recombinant Proteins; Tritium | 1998 |
In vitro effect of angiotensin II on GABA release in rat hippocampus.
Topics: Angiotensin II; Animals; Calcium; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Nipecotic Acids; Potassium Chloride; Proline; Rats; Rats, Wistar | 1998 |
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Binding, Competitive; Bradycardia; Dopamine Agents; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hypotension; Levodopa; Male; Microinjections; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus; Tritium | 1999 |
Cholinergic and GABAergic inputs drive patterned spontaneous motoneuron activity before target contact.
Topics: Acetylcholine; Action Potentials; Animals; Bicuculline; Chick Embryo; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Motor Neurons; Neuromuscular Junction; Nipecotic Acids; Proline; Receptors, Nicotinic; Synaptic Transmission | 1999 |
Identification and characterization of GABA, proline and quaternary ammonium compound transporters from Arabidopsis thaliana.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Arabidopsis; gamma-Aminobutyric Acid; Genetic Complementation Test; Membrane Transport Proteins; Mutagenesis; Proline | 1999 |
Involvement of cholinergic and GABAergic systems in the reversal of memory disruption by NS-105, a cognition enhancer.
Topics: Acetylcholine; Animals; Avoidance Learning; Basal Ganglia; Cerebral Cortex; Cognition; Electroshock; gamma-Aminobutyric Acid; Male; Memory Disorders; Muscarinic Antagonists; Nootropic Agents; Parasympathetic Nervous System; Piperidines; Proline; Rats; Rats, Wistar; Receptors, GABA-B; Scopolamine; Synaptosomes | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
[3H] gamma-aminobutyric acid transport in rat substantia nigra pars reticulata synaptosomes: pharmacological characterization and phorbol ester-induced inhibition.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basal Ganglia; beta-Alanine; Biological Transport; Carcinogens; Colforsin; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Substantia Nigra; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium | 1999 |
Endogenous GABA potentiates the potassium-induced release of dopamine in striatum of the freely moving rat: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Microdialysis; Models, Neurological; Motor Activity; Nipecotic Acids; Potassium; Proline; Rats; Rats, Wistar; Substantia Nigra; Tetrodotoxin | 1999 |
Development and role of GABA(A) receptor-mediated synaptic potentials during swimming in postembryonic Xenopus laevis tadpoles.
Topics: Animals; Bicuculline; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine Agents; Larva; Neurons; Nipecotic Acids; Pregnanolone; Proline; Receptors, GABA-A; Rhombencephalon; Spinal Cord; Strychnine; Swimming; Synapses; Xenopus laevis | 1999 |
A microdialysis study on the mechanism of action of gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Nipecotic Acids; Potassium; Proline; Rats; Rats, Wistar; Substantia Nigra | 2000 |
Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Calcium; Carrier Proteins; Chloride Channels; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Proteins; Membrane Transport Proteins; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Nipecotic Acids; Organic Anion Transporters; Perfusion; Proline; Protein Kinase C; Rats; Rats, Wistar; Receptors, Nicotinic; Sodium Channel Blockers; Tritium | 2000 |
Molecular cloning and functional characterization of two kinds of betaine-aldehyde dehydrogenase in betaine-accumulating mangrove Avicennia marina (Forsk.) Vierh.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Betaine; Betaine-Aldehyde Dehydrogenase; Calcium Chloride; Carbohydrate Metabolism; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Stability; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hot Temperature; Isoenzymes; Molecular Sequence Data; Osmolar Concentration; Oxidation-Reduction; Oxygenases; Plant Leaves; Plants, Medicinal; Potassium Chloride; Proline; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sodium Chloride; Species Specificity; Spinacia oleracea; Substrate Specificity; Tissue Distribution | 2001 |
Identification and characterization of a lysosomal transporter for small neutral amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids, Neutral; Animals; Brain; Caenorhabditis elegans; Carrier Proteins; Cell Line; Cerebral Cortex; Cloning, Molecular; Drosophila melanogaster; Evolution, Molecular; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Lysosomes; Male; Molecular Sequence Data; Phylogeny; Proline; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology, Amino Acid; Symporters; Transfection | 2001 |
Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement.
Topics: Animals; Barbiturates; Cattle; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Humans; L Cells; Ligands; Mice; Mutation; Proline; Receptors, GABA-A; Xenopus laevis | 2002 |
STUDIES ON NITROGEN METABOLISM IN TOBACCO PLANTS. VI. METABOLISM OF GLUTAMIC ACID, GAMMA-AMINOBUTYRIC ACID, AND PROLINE IN TOBACCO LEAVES.
Topics: Amino Acids; Aminobutyrates; Autoanalysis; Carbon Isotopes; Chromatography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Nicotiana; Nitrogen; Photosynthesis; Proline; Research | 1964 |
Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.
Topics: Amino Acid Transport Systems; Biological Transport; Caco-2 Cells; gamma-Aminobutyric Acid; Glycine; Humans; Proline; Protons; Symporters; Tritium | 2004 |
Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Carboxylic Acids; Cations; Crotonates; Cyclopropanes; Dose-Response Relationship, Drug; Electric Conductivity; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Ion Channel Gating; Isoxazoles; Molecular Sequence Data; Molecular Structure; Muscimol; Mutagenesis, Site-Directed; Proline; Protein Subunits; Receptors, GABA; Static Electricity; Structure-Activity Relationship | 2004 |
The AtProT family. Compatible solute transporters with similar substrate specificity but differential expression patterns.
Topics: Arabidopsis; Arabidopsis Proteins; Betaine; Carrier Proteins; Cell Membrane; gamma-Aminobutyric Acid; Gene Expression; Multigene Family; Nicotiana; Phylogeny; Proline; Saccharomyces cerevisiae; Substrate Specificity | 2005 |
GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Arabidopsis; gamma-Aminobutyric Acid; Hydrogen Peroxide; Light; Mutation; Proline; Reactive Oxygen Species; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Vigabatrin | 2005 |
Synthesis of 4-aryl-2-pyrrolidones and beta-aryl-gamma-amino-butyric acid (GABA) analogues by Heck arylation of 3-pyrrolines with arenediazonium tetrafluoroborates. Synthesis of (+/-)-rolipram on a multigram scale and chromatographic resolution by semipre
Topics: Borates; Chromatography, Ion Exchange; Diazonium Compounds; Fluorine Compounds; gamma-Aminobutyric Acid; Phosphodiesterase Inhibitors; Proline; Pyrrolidinones; Rolipram; Stereoisomerism | 2005 |
Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid.
Topics: Animals; Biological Transport; Brain; Cattle; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Transport Modulators; Membrane Transport Proteins; Molecular Structure; Proline; Structure-Activity Relationship; Swine | 2005 |
A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport.
Topics: Animals; Base Sequence; Biological Transport; Biotinylation; Blotting, Western; Cell Membrane; Codon; Cytoplasm; DNA Mutational Analysis; DNA Primers; DNA, Complementary; gamma-Aminobutyric Acid; Glycine; Humans; K Cl- Cotransporters; Mice; Molecular Sequence Data; Mutation; Neurons; Oocytes; Proline; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Complementary; Sequence Homology, Amino Acid; Symporters; Xenopus laevis | 2006 |
Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.
Topics: Amino Acid Transport Systems; Biological Transport; Caco-2 Cells; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Microvilli; Proline; Symporters; Vigabatrin | 2006 |
AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana.
Topics: Animals; Arabidopsis; Arabidopsis Proteins; Betaine; Binding, Competitive; Biological Transport; Butylamines; Cell Membrane; Cellular Senescence; Chlorophyll; DNA; Electrophysiology; Escherichia coli; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Genetic Complementation Test; Glycine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Models, Biological; Models, Chemical; Nicotiana; Oocytes; Phylogeny; Proline; Protein Binding; Protein Biosynthesis; Protoplasts; RNA; RNA, Messenger; Saccharomyces cerevisiae; Substrate Specificity; Wound Healing; Xenopus | 2006 |
New highly potent GABA uptake inhibitors selective for GAT-1 and GAT-3 derived from (R)- and (S)-proline and homologous pyrrolidine-2-alkanoic acids.
Topics: Alkanes; Alkylation; Carboxylic Acids; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Methylation; Molecular Structure; Proline; Pyrrolidines; Saponins; Stereoisomerism; Structure-Activity Relationship | 2006 |
Vagal afferent control of opioidergic effects in rat brainstem circuits.
Topics: Animals; Brain Stem; CREB-Binding Protein; Cyclic AMP; Enkephalin, Methionine; Evoked Potentials; gamma-Aminobutyric Acid; Gastrointestinal Tract; Glutamate Decarboxylase; Glutamates; In Vitro Techniques; Isoenzymes; Narcotic Antagonists; Neural Inhibition; Neurons, Afferent; Opioid Peptides; Phosphorylation; Presynaptic Terminals; Proline; Rats; Receptors, Metabotropic Glutamate; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission; Vagotomy; Vagus Nerve | 2006 |
Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo.
Topics: Animals; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamates; Male; Neural Inhibition; Physical Stimulation; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Vibrissae | 2007 |
Gene transcription in the leaves of rice undergoing salt-induced morphological changes (Oryza sativa L.).
Topics: 4-Aminobutyrate Transaminase; Ascorbate Peroxidases; Catalase; Cytosol; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Profiling; Glutathione Reductase; Oligonucleotide Array Sequence Analysis; Ornithine-Oxo-Acid Transaminase; Oryza; Peroxidases; Plant Leaves; Proline; Sodium Chloride; Superoxide Dismutase; Thylakoids; Transcription, Genetic; Up-Regulation | 2007 |
Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cystine; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Molecular Sequence Data; Patch-Clamp Techniques; Pentobarbital; Proline; Protein Conformation; Receptors, GABA-A; Receptors, GABA-B | 2008 |
Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: characterization of conditions for affinity and transport experiments in Caco-2 cells.
Topics: Algorithms; Amino Acid Transport Systems; Amino Acids; Biological Transport, Active; Caco-2 Cells; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kinetics; Ligands; Muscimol; Neurotransmitter Uptake Inhibitors; Osmolar Concentration; Proline; Symporters | 2008 |
Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.
Topics: Acetates; Animals; Cell Line; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Mice; Proline; Pyrrolidines; Structure-Activity Relationship | 2009 |
Proline antagonizes GABA-induced quenching of quorum-sensing in Agrobacterium tumefaciens.
Topics: Agrobacterium tumefaciens; Arabidopsis; Bacterial Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation, Bacterial; Host-Pathogen Interactions; Mutation; Nicotiana; Plant Tumors; Plants; Plants, Genetically Modified; Proline; Quorum Sensing; Receptors, GABA; Solanum lycopersicum; Time Factors; Valine; Virulence | 2009 |
Cell-mediated neuroprotection in a mouse model of human tauopathy.
Topics: Age Factors; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Transplantation; Cell- and Tissue-Based Therapy; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Growth Factor; Nerve Tissue Proteins; Neurons; Oligodendrocyte Transcription Factor 2; Proline; RNA, Messenger; Serine; Stem Cells; tau Proteins; Tauopathies | 2010 |
Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).
Topics: Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Biological Transport; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Models, Chemical; Oocytes; Phenotype; Proline; Rats; Symporters; Tryptophan; Xenopus laevis | 2011 |
Effect of exogenous γ-aminobutyric acid treatment on proline accumulation and chilling injury in peach fruit after long-term cold storage.
Topics: Cold Temperature; Food Preservation; Fruit; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Prunus; Time Factors | 2011 |
[Effect of dipeptide neurotensin analog dilept on extracellular concentrations of glutamate, GABA and HVA in N. accumbens of rat brain].
Topics: Animals; Antipsychotic Agents; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Neurotensin; Nucleus Accumbens; Proline; Rats; Rats, Wistar; Tyrosine | 2010 |
A mitochondrial GABA permease connects the GABA shunt and the TCA cycle, and is essential for normal carbon metabolism.
Topics: Amino Acid Sequence; Analysis of Variance; Arabidopsis; Arabidopsis Proteins; Blotting, Southern; Carbon; Carbon Dioxide; Citric Acid Cycle; Cytosol; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Genetic Complementation Test; Genetic Vectors; Genotype; Green Fluorescent Proteins; Immunoblotting; Light; Microscopy, Confocal; Mitochondria; Mutagenesis, Insertional; Nicotiana; Open Reading Frames; Plant Leaves; Plant Roots; Proline; Protoplasts; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Seedlings | 2011 |
The dominant glutamic acid metabolic flux to produce γ-amino butyric acid over proline in Nicotiana tabacum leaves under water stress relates to its significant role in antioxidant activity.
Topics: Antioxidants; Dehydration; Free Radical Scavengers; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamate Decarboxylase; Glutamate-5-Semialdehyde Dehydrogenase; Glutamic Acid; Hydrogen Peroxide; Nicotiana; Plant Leaves; Proline; Singlet Oxygen; Superoxides; Water | 2011 |
Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Disease Models, Animal; Female; Functional Laterality; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Stem Cells; Phosphorylation; Proline; Serine; Stem Cell Transplantation; tau Proteins; Tauopathies; Time Factors | 2011 |
Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes.
Topics: Acetaldehyde; Alkenes; Biocatalysis; Carbon; gamma-Aminobutyric Acid; Isomerases; Nitro Compounds; Proline; Stereoisomerism | 2013 |
Conformation of the neurotransmitter γ-aminobutyric acid in liquid water.
Topics: gamma-Aminobutyric Acid; Molecular Conformation; Neurotransmitter Agents; Proline; Water | 2014 |
Characterization of the salt stress vulnerability of three invasive freshwater plant species using a metabolic profiling approach.
Topics: Aquatic Organisms; Biomass; Carbohydrate Metabolism; Fresh Water; gamma-Aminobutyric Acid; Hydrocharitaceae; Introduced Species; Magnoliopsida; Metabolomics; Onagraceae; Photosynthesis; Proline; Sodium Chloride; Stress, Physiological | 2015 |
Connecting proline and γ-aminobutyric acid in stressed plants through non-enzymatic reactions.
Topics: Amines; gamma-Aminobutyric Acid; Hydroxyl Radical; Models, Molecular; Molecular Conformation; Oxidative Stress; Plants; Proline | 2015 |
Physiological performance and differential expression profiling of genes associated with drought tolerance in root tissue of four contrasting varieties of two Gossypium species.
Topics: Adaptation, Physiological; Biomass; Carbon; Carbon Isotopes; Droughts; gamma-Aminobutyric Acid; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Gossypium; Lipid Peroxidation; Mannitol; Metabolome; Nitrogen; Osmosis; Plant Roots; Plant Shoots; Principal Component Analysis; Proline; Sterols; Stress, Physiological; Superoxide Dismutase | 2016 |
Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.
Topics: Animals; Biomarkers; Cystamine; Flax; gamma-Aminobutyric Acid; Glycocholic Acid; Indoles; Male; Metabolomics; Nandrolone; Nutritional Status; Oxindoles; Proline; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid; Vitamin B 6; Vitamin B 6 Deficiency | 2016 |
GABAA Receptor Binding Assays of Standardized Leonurus cardiaca and Leonurus japonicus Extracts as Well as Their Isolated Constituents.
Topics: Animals; Anti-Anxiety Agents; Gallic Acid; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Leonurus; Male; Molecular Structure; Plant Extracts; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Standards | 2015 |
Metabolites and hormones are involved in the intraspecific variability of drought hardening in radiata pine.
Topics: Droughts; gamma-Aminobutyric Acid; Pinus; Plant Breeding; Plant Growth Regulators; Proline; Species Specificity | 2015 |
Contribution of polyamines metabolism and GABA shunt to chilling tolerance induced by nitric oxide in cold-stored banana fruit.
Topics: Carboxy-Lyases; Cold Temperature; Food Storage; Fruit; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Musa; Nitric Oxide; Plant Proteins; Polyamines; Proline | 2016 |
Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated Caco-2, LLC-PK1 and rat renal SKPT cells.
Topics: Aminolevulinic Acid; Animals; beta-Alanine; Caco-2 Cells; Cell Line; gamma-Aminobutyric Acid; Humans; Isoxazoles; Kidney; LLC-PK1 Cells; Membrane Glycoproteins; Membrane Transport Proteins; Nicotinic Acids; Nipecotic Acids; Osmolar Concentration; Osmosis; Proline; Rats; RNA, Messenger; Swine; Taurine; Vigabatrin | 2016 |
Discrimination of some European vinegars with protected denomination of origin as a function of their amino acid and biogenic amine content.
Topics: Acetic Acid; Amino Acids; Biogenic Amines; Chromatography, High Pressure Liquid; Europe; Food Analysis; Food Contamination; Food Handling; Fruit; gamma-Aminobutyric Acid; Glycine; Humans; Malonates; Proline; Vitis | 2016 |
Short- and long-term effects of carbohydrate limitation on sugar and organic acid accumulation during mandarin fruit growth.
Topics: Citric Acid; Citrus; Crop Production; Crops, Agricultural; Dietary Sucrose; Down-Regulation; France; Fructose; Fruit; gamma-Aminobutyric Acid; Glucose; Humans; Malates; Nutritive Value; Phloem; Plant Leaves; Principal Component Analysis; Proline; Time Factors; Up-Regulation | 2016 |
Plant GABA:proline ratio modulates dissemination of the virulence Ti plasmid within the Agrobacterium tumefaciens hosted population.
Topics: Agrobacterium tumefaciens; Arabidopsis; Bacterial Proteins; Biological Transport; gamma-Aminobutyric Acid; Glutamic Acid; Models, Biological; Plant Tumor-Inducing Plasmids; Plant Tumors; Polyamines; Proline; Quorum Sensing; Signal Transduction; Virulence | 2016 |
Exogenous Melatonin Treatment Increases Chilling Tolerance and Induces Defense Response in Harvested Peach Fruit during Cold Storage.
Topics: Cold Temperature; Food Preservatives; Food Storage; Fruit; gamma-Aminobutyric Acid; Melatonin; Proline; Prunus persica | 2016 |
(1)H NMR foodomics reveals that the biodynamic and the organic cultivation managements produce different grape berries (Vitis vinifera L. cv. Sangiovese).
Topics: Caffeic Acids; Fruit; gamma-Aminobutyric Acid; Isoleucine; Magnetic Resonance Spectroscopy; Multivariate Analysis; Organic Agriculture; Perchlorates; Proline; Valine; Vitis; Wine | 2016 |
Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade.
Topics: Animals; Central Nervous System; Cytosol; Disease Models, Animal; Gamma Rhythm; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamate Decarboxylase; Humans; Mice; Proline; Proline Oxidase; Schizophrenia; Vigabatrin | 2016 |
l-Proline, GABA Synthesis and Gamma Oscillations in Schizophrenia.
Topics: GABAergic Neurons; gamma-Aminobutyric Acid; Parvalbumins; Prefrontal Cortex; Proline; Schizophrenia | 2016 |
Effect of Exogenous Nitro Oxide on Chilling Tolerance, Polyamine, Proline, and γ-Aminobutyric Acid in Bamboo Shoots (Phyllostachys praecox f. prevernalis).
Topics: Carboxy-Lyases; Cold Temperature; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Nitric Oxide; Nitric Oxide Synthase; Ornithine Decarboxylase; Plant Proteins; Plant Shoots; Poaceae; Polyamines; Proline | 2017 |
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Catalytic Domain; Crystallography, X-Ray; Dopamine; Dopamine Antagonists; Drug Design; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glucose; Humans; Male; Models, Molecular; Proline; Rats; Rats, Sprague-Dawley | 2018 |
WIND1 induces dynamic metabolomic reprogramming during regeneration in Brassica napus.
Topics: Arabidopsis; Arabidopsis Proteins; Brassica napus; Cellular Reprogramming; Cytokinins; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Genes, Plant; Indoleacetic Acids; Organogenesis, Plant; Plant Shoots; Plants, Genetically Modified; Proline; Putrescine; Regeneration; Transcription Factors | 2018 |
Role of Endogenous Metabolite Alterations in Neuropsychiatric Disease.
Topics: DiGeorge Syndrome; gamma-Aminobutyric Acid; Humans; Metabolism, Inborn Errors; Metabolomics; Molecular Mimicry; Neuronal Plasticity; Neurotransmitter Agents; Proline; Proline Oxidase; Schizophrenia; Schizophrenic Psychology | 2018 |
Two-Dimensional Proton Magnetic Resonance Spectroscopy versus J-Editing for GABA Quantification in Human Brain: Insights from a GABA-Aminotransferase Inhibitor Study.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Brain; Enzyme Inhibitors; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Proline; Proton Magnetic Resonance Spectroscopy; Young Adult | 2018 |
Fermentation performance and metabolomic analysis of an engineered high-yield PUFA-producing strain of Schizochytrium sp.
Topics: Bioengineering; Biomarkers; Bioreactors; Biotechnology; Cell Proliferation; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Fermentation; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Lipid Metabolism; Lipids; Metabolomics; Multivariate Analysis; Proline; Stramenopiles | 2019 |
Exogenous γ-aminobutyric acid treatment improves the cold tolerance of zucchini fruit during postharvest storage.
Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Alanine; Amine Oxidase (Copper-Containing); Cell Death; Cold Temperature; Cucurbita; Food Storage; Fruit; Fumarates; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Malates; NAD; Proline; Putrescine | 2019 |
Swift metabolite changes and leaf shedding are milestones in the acclimation process of grapevine under prolonged water stress.
Topics: Fruit; gamma-Aminobutyric Acid; Osmosis; Plant Leaves; Proline; Vitis; Water | 2019 |
The Role of IP3 in NO-Enhanced Chilling Tolerance in Peach Fruit.
Topics: Aldehyde Dehydrogenase; Cold Temperature; Food Storage; Fruit; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Inositol 1,4,5-Trisphosphate; Mitochondrial Proteins; Nitric Oxide; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Plant Proteins; Polyamine Oxidase; Proline; Prunus persica | 2019 |
Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study.
Topics: Alanine; Amino Acids, Branched-Chain; Autoantibodies; Child, Preschool; Dehydroascorbic Acid; Diabetes Mellitus, Type 1; Fatty Acids; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamate Decarboxylase; Humans; Infant; Infant, Newborn; Insulin Antibodies; Longitudinal Studies; Male; Metabolome; Methionine; Phosphatidylethanolamines; Prodromal Symptoms; Proline; Risk; Triglycerides | 2020 |
A Noninvasive Urine Metabolome Panel as Potential Biomarkers for Diagnosis of T Cell-Mediated Renal Transplant Rejection.
Topics: Acute Disease; Adenosine Diphosphate; Adult; Biomarkers; Cholesterol Esters; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Graft Rejection; Graft Survival; Hippurates; Humans; Kidney Transplantation; Male; Metabolome; Middle Aged; NAD; Niacin; Niacinamide; Proline; Renal Insufficiency, Chronic; ROC Curve; Spermidine; T-Lymphocytes | 2020 |
Effects of nitric oxide on the GABA, polyamines, and proline in tea (Camellia sinensis) roots under cold stress.
Topics: Camellia sinensis; Carboxy-Lyases; Cold Temperature; Cold-Shock Response; Cyclic N-Oxides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Imidazoles; Nitric Oxide; Nitric Oxide Donors; Ornithine Decarboxylase; Plant Leaves; Plant Proteins; Plant Roots; Polyamines; Proline; Putrescine; S-Nitroso-N-Acetylpenicillamine; Spermidine; Spermine; Tea | 2020 |
Plasma amino acids profile in first-episode psychosis, unaffected siblings and community-based controls.
Topics: Adult; Amino Acids; Antipsychotic Agents; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Glycine; Humans; Linear Models; Male; Proline; Psychotic Disorders; Siblings; Tryptophan; Young Adult | 2020 |
Metabolism of glutamic acid to alanine, proline, and γ-aminobutyric acid during takuan-zuke processing of radish root.
Topics: 4-Aminobutyrate Transaminase; Alanine; Desiccation; Food Handling; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrogen-Ion Concentration; Plant Roots; Polymerase Chain Reaction; Proline; Raphanus; RNA, Plant; Sodium Chloride | 2021 |
Day and Night Fluctuations in GABA Biosynthesis Contribute to Drought Responses in
Topics: Circadian Rhythm; Droughts; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate Dehydrogenase; Glutamic Acid; Nicotiana; Proline | 2021 |
Pre-harvest spray of GABA and spermine delays postharvest senescence and alleviates chilling injury of gerbera cut flowers during cold storage.
Topics: Antioxidants; Asteraceae; Biomass; Catalase; Catechol Oxidase; Cell Membrane; Cryopreservation; Electrolytes; Flowers; gamma-Aminobutyric Acid; Hydrogen Peroxide; Lipoxygenase; Malondialdehyde; Models, Biological; Peroxidase; Phospholipase D; Plant Proteins; Proline; Spermine; Superoxide Dismutase | 2021 |
Enantiocomplementary Michael Additions of Acetaldehyde to Aliphatic Nitroalkenes Catalyzed by Proline-Based Carboligases.
Topics: Acetaldehyde; Alkenes; Biocatalysis; Catalysis; gamma-Aminobutyric Acid; Isomerases; Nitro Compounds; Pregabalin; Proline; Stereoisomerism | 2022 |
Exogenous phytosulfokine α (PSKα) alleviates chilling injury of banana by modulating metabolisms of nitric oxide, polyamine, proline, and γ-aminobutyric acid.
Topics: gamma-Aminobutyric Acid; Musa; Nitric Oxide; Polyamines; Proline; Putrescine | 2022 |
Polyamines Metabolism Interacts with γ-Aminobutyric Acid, Proline and Nitrogen Metabolisms to Affect Drought Tolerance of Creeping Bentgrass.
Topics: Agrostis; Droughts; gamma-Aminobutyric Acid; Glutamic Acid; Nitrogen; Polyamines; Proline; Spermine | 2022 |
Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars.
Topics: Amino Acids; gamma-Aminobutyric Acid; Ornithine; Oryza; Proline; Putrescine; Pyrroles; Pyruvaldehyde; Salt Stress | 2022 |
Microbiota alterations in proline metabolism impact depression.
Topics: Animals; Depression; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Humans; Mice; Microbiota; Proline | 2022 |
The effects of dietary proline, β-alanine, and γ-aminobutyric acid (GABA) on the nest construction behavior in the Oriental hornet (Vespa orientalis).
Topics: Amino Acids; Animals; beta-Alanine; gamma-Aminobutyric Acid; Larva; Plant Nectar; Proline; Wasps | 2022 |
Foliar application of procyanidins enhanced the biosynthesis of 2-acetyl-1-pyrroline in aromatic rice (Oryza sativa L.).
Topics: gamma-Aminobutyric Acid; Odorants; Oryza; Proanthocyanidins; Proline; Pyrroles | 2022 |
GABA
Topics: gamma-Aminobutyric Acid; Ion Channel Gating; Patch-Clamp Techniques; Proline; Receptors, GABA-A | 2022 |
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress.
Topics: Aspartic Acid; Beta vulgaris; Chlorides; Citric Acid; Cysteine; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hot Temperature; Mannitol; Metabolic Networks and Pathways; Plant Roots; Proline; Salinity; Salts; Sodium Chloride; Stress, Physiological; Sugars; Tryptophan; Tyrosine | 2022 |
Urinary metabolomics, dietary salt intake and blood pressure: the African-PREDICT study.
Topics: Adult; African People; Amino Acids; Blood Pressure; Cardiovascular Diseases; gamma-Aminobutyric Acid; Humans; Hypertension; Proline; Serine; Sexually Transmitted Diseases; Sodium Chloride, Dietary | 2023 |
Hydroxy proline and gamma-aminobutyric acid: markers of susceptibility to vine decline disease caused by the fungus
Topics: Amino Acids; Antifibrinolytic Agents; Ascomycota; Cucumis melo; Flower Essences; gamma-Aminobutyric Acid; Proline | 2023 |
Zinc supplementation and light intensity affect 2-acetyl-1-pyrroline (2AP) formation in fragrant rice.
Topics: Antioxidants; Carboxylic Acids; Dietary Supplements; gamma-Aminobutyric Acid; Odorants; Oryza; Peroxidases; Proline; Proline Oxidase; Superoxide Dismutase; Zinc | 2023 |
Exogenous phytosulfokine α alleviates chilling injury of loquat fruit via regulating sugar, proline, polyamine and γ-aminobutyric acid metabolisms.
Topics: Carbohydrates; Cold Temperature; Fruit; gamma-Aminobutyric Acid; Polyamines; Proline; Sugars | 2024 |