proline and deuterium

proline has been researched along with deuterium in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (42.86)	18.7374
1990's	9 (12.86)	18.2507
2000's	20 (28.57)	29.6817
2010's	9 (12.86)	24.3611
2020's	2 (2.86)	2.80

Authors

Authors	Studies
Cronholm, T	1
Anteunis, MJ; Becu, C; Borremans, FA; Sleeckx, J	1
Burghardt, BA; Charnecki, AM; Delaney, CM; Felix, AM; Liebman, AA; Meienhofer, J; Mowles, T; Wang, CT	1
Celma, C; Giralt, E	1
Burke, JF; Jaksic, T; Wagner, DA; Young, VR	1
Crawford, A; Hunter, BK; Wood, JM	1
Albery, WJ; Belasco, JG; Knowles, JR	1
Alpert, N; Burke, JF; Molnar, JA; Young, VR	1
Deslauriers, R; McGregor, WH; Sarantakis, D; Smith, IC	1
Bornstein, P; Ehrlich, HP	1
Deslauriers, R; Smith, IC; Walter, R	2
Deslauriers, R; Garrigou-Lagrange, C; McGregor, H; Saitô, H; Sarantakis, D; Smith, IC; Walter, R	1
Bedford, GR; Feeney, J; Wessels, PL	1
Abeles, RH; Schonbrunn, A; Walsh, CT	1
Bedford, GR; Sadler, PJ	1
Grathwohl, C; Wüthrich, K	1
Blout, ER; Deber, CM; Torchia, DA; Wong, SC	1
Christensen, HN; Quay, S	1
Patel, DJ	1
Gibbons, WA; Randall, EW; Sogn, JA	1
Glasel, JA; Hruby, VJ; McKelvy, JF; Spatola, AF	1
Brewster, AI; Glasel, JA; Hruby, VJ; Tonelli, AE	1
Alworth, WL; Keenan, MV	1
Ellenberger, M; Pogliani, L	1
Mitchell, LW; Onishi, T; Urry, DW	1
Torchia, DA	1
Faulstich, H; Goodman, M; Naider, F; Patel, DJ; Tonelli, AE; Wieland, T	1
Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ	1
Abeles, RH; Cardinale, GJ	1
Abeles, RH; Hodgins, DS	1
Fujita, T; Iida, A; Nagaoka, Y; Tachikawa, E	1
Houry, WA; Scheraga, HA	1
Gaggelli, E; Grzonka, Z; Kasprzykowski, F; Kozlowski, H; Maccotta, A; Valensin, G	1
el Mokdad, N; Fischer, G; Reimer, U; Schutkowski, M	1
Raleigh, DP; Wu, WJ	1
Gehrig, P; Plückthun, A; Ramm, K	1
Huyghues-Despointes, BM; Pace, CN; Scholtz, JM	1
Kentsis, A; Krantz, BA; Moran, LB; Sosnick, TR	1
Jäger, M; Plückthun, A	1
Begley, TP; Kivirikko, KI; Moon, HS; Myllyharju, J; Pirskanen, A; Wu, M	1
Beaumier, L; Castillo, L; Lu, XM; Ryan, CM; Tompkins, RG; Young, VR; Yu, YM	1
Hartleib, J; Klimmek, O; Lin, YJ; Löhr, F; Pfeiffer, S; Rüterjans, H	1
Ikawa, S; Sugawara, M; Tonan, K	1
Huong, NT; Inatomi, H; Yoshihashi, T	1
Bader, R; Beck-Sickinger, AG; Lerch, M; Rytz, G; Zerbe, O	1
Bigotti, MG; Bren, KL; Cutruzzolà, F; Russell, BS; Zhong, L	1
LAMPORT, DT	1
Chekmenev, EY; Pometun, MS; Wittebort, RJ	1
Kazazić, S; Klasinc, L; Rozman, M; Srzić, D	1
Ferdani, R; Gokel, GW; Pajewski, R; Schlesinger, PH	1
Ball, RO; Pencharz, PB; Shoveller, AK; Urschel, KL	1
Barraclough, P; Dieterich, P; Spray, CA; Young, DW	1
Baumruk, V; Bour, P; Kapitán, J; Kopecký, V; Pohl, R	1
Aregger, R; Bernado, P; Blackledge, M; Dames, SA; Grzesiek, S; Vajpai, N	1
Basu, G; Chakrabarti, P; Dasgupta, B	1
Chugh, J; Hosur, RV; Sharma, S	1
Craven, CJ; Giannini, S; Hounslow, AM; Morgan, GJ; Staniforth, RA; Turk, V; Waltho, JP; Zerovnik, E	1
Armstrong, A; Blackmond, DG; Broadbelt, LJ; Zotova, N	1
Andreas, LB; Griffin, RG; Maly, T; Smith, AA	1
Gschwind, RM; Schmid, MB; Zeitler, K	1
Ganim, Z; Jansen, TL; Knoester, J; Lessing, J; Meisl, G; Roy, S; Tokmakoff, A	1
Holland, GP; Shi, X; Yarger, JL	2
Kluczyk, A; Rudowska, M; Stefanowicz, P; Szewczuk, Z; Wieczorek, R	1
Aichholz, R; Blanz, J; Blasco, F; Caravatti, G; Fairhurst, RA; Fritsch, C; Guagnano, V; Maira, SM; Schnell, C; Seiler, FH; Wipfli, P	1
Eckelmann, D; Kusari, S; Spiteller, M	1
Myers, EL; Palte, MJ; Raines, RT	1
Allen, LH; Devi, S; Dharmar, M; Holt, RR; Keen, CL; Kurpad, AV; Preston, T; Sheshshayee, MS; Varkey, A	1
Chernobrovkin, AL; Eriksson, G; Gharibi, H; Kalthoff, DC; Kitchener, AC; Lidén, K; Makarov, AA; Saei, AA; Timmons, Z; Zubarev, RA	1

Trials

2 trial(s) available for proline and deuterium

Article	Year
Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Arginine; Burns; Carbon Isotopes; Deuterium; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen Isotopes; Ornithine; Oxidation-Reduction; Parenteral Nutrition, Total; Proline	2001
Amino Acid Digestibility of Extruded Chickpea and Yellow Pea Protein is High and Comparable in Moderately Stunted South Indian Children with Use of a Dual Stable Isotope Tracer Method. The Journal of nutrition, 2020, 05-01, Volume: 150, Issue:5 Topics: Amino Acids; Carbon Isotopes; Child; Cicer; Deuterium; Digestion; Female; Food Handling; Growth Disorders; Humans; India; Lysine; Male; Pisum sativum; Plant Proteins; Proline; Trypsin Inhibitors	2020

Article

Year

Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal.

American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:3

Topics: Adult; Aged; Aged, 80 and over; Arginine; Burns; Carbon Isotopes; Deuterium; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen Isotopes; Ornithine; Oxidation-Reduction; Parenteral Nutrition, Total; Proline

2001

Amino Acid Digestibility of Extruded Chickpea and Yellow Pea Protein is High and Comparable in Moderately Stunted South Indian Children with Use of a Dual Stable Isotope Tracer Method.

The Journal of nutrition, 2020, 05-01, Volume: 150, Issue:5

Topics: Amino Acids; Carbon Isotopes; Child; Cicer; Deuterium; Digestion; Female; Food Handling; Growth Disorders; Humans; India; Lysine; Male; Pisum sativum; Plant Proteins; Proline; Trypsin Inhibitors

2020

Other Studies

68 other study(ies) available for proline and deuterium

Article	Year
Incorporation of the hydrogen atoms of ethanol into amino acids in rat liver in vivo. Biochimica et biophysica acta, 1979, Mar-07, Volume: 583, Issue:2 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Ethanol; Female; Glutamates; Hydrogen; Liver; NAD; Proline; Rats	1979
Preparation of racemic 2r-carboxy-trans, trans-3,4-dideutero-pyrrolidine (DL-trans, trans-3,4-dideutero-proline) and unambiguous assignment of protons in the 1H n.m.r. spectrum of proline. International journal of peptide and protein research, 1979, Volume: 14, Issue:5 Topics: Chemical Phenomena; Chemistry; Deuterium; Isomerism; Molecular Conformation; Proline; Protons; Spectrum Analysis	1979
Synthesis, biological activity, and tritiation of L-3, 4-dehydroproline-containing peptides. International journal of peptide and protein research, 1977, Volume: 10, Issue:4 Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Deuterium; In Vitro Techniques; Peptides; Proline; Rats; Thyrotropin; Tritium	1977
Determination of the enantiomeric purity of synthetic peptides by gas chromatography-mass spectrometry. Journal of chromatography, 1991, Jan-02, Volume: 562, Issue:1-2 Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Deuterium; Esters; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydrolysis; Indicators and Reagents; Isotope Labeling; Molecular Sequence Data; Peptides; Proline; Stereoisomerism	1991
Proline metabolism in adult male burned patients and healthy control subjects. The American journal of clinical nutrition, 1991, Volume: 54, Issue:2 Topics: Adult; Burns; Carbon Isotopes; Deuterium; Humans; Kinetics; Leucine; Male; Oxidation-Reduction; Proline	1991
Nuclear magnetic resonance spectroscopy reveals the metabolic origins of proline excreted by an Escherichia coli derivative during growth on [13C]acetate. Applied and environmental microbiology, 1987, Volume: 53, Issue:10 Topics: Acetates; Carbon; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrogen; Magnetic Resonance Spectroscopy; Proline	1987
Energetics of proline racemase: double fractionation experiment, a test for concertedness and for transition-state dominance. Biochemistry, 1986, May-06, Volume: 25, Issue:9 Topics: Amino Acid Isomerases; Clostridium; Deuterium; Kinetics; Mathematics; Proline; Radioisotope Dilution Technique; Stereoisomerism; Thermodynamics	1986
Synthesis and degradation rates of collagens in vivo in whole skin of rats, studied with 1802 labelling. The Biochemical journal, 1986, Dec-01, Volume: 240, Issue:2 Topics: Animals; Collagen; Deuterium; Kinetics; Male; Oxygen Isotopes; Proline; Rats; Rats, Inbred Strains; Skin	1986
Carbon-13 nuclear magnetic resonance studies of structure and function in thyrotropin-releasing factor. Determination of the tautomeric form of histidine and relationship to biology activity. Biochemistry, 1974, Aug-13, Volume: 13, Issue:17 Topics: Carbon Isotopes; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Imidazoles; Magnetic Resonance Spectroscopy; Methylation; Proline; Protein Conformation; Protons; Stereoisomerism; Structure-Activity Relationship; Thyrotropin-Releasing Hormone	1974
Microtubules in transcellular movement of procollagen. Nature: New biology, 1972, Aug-30, Volume: 238, Issue:87 Topics: Animals; Animals, Newborn; Biological Transport; Carbon; Chickens; Colchicine; Collagen; Cyanides; Cyclic AMP; Deuterium; Hydroxyproline; Microtubules; Mycotoxins; Organ Culture Techniques; Phenylhydrazines; Proline; Protein Biosynthesis; Pyrimidine Nucleotides; Rats; Skull; Tritium; Vinblastine	1972
13C nuclear magnetic resonance studies of the conformation of the X-pro bond in the oligopeptide hormones, thyrotropin-releasing hormone, luteinizing hormone-releasing factor, angiotensin and melanocyte-stimulating hormone release-inhibiting factor. Biochemical and biophysical research communications, 1973, Jul-02, Volume: 53, Issue:1 Topics: Angiotensin II; Carbon Isotopes; Deuterium; Gonadotropin-Releasing Hormone; Isomerism; Magnetic Resonance Spectroscopy; Melanocyte-Stimulating Hormones; Pituitary Hormone-Releasing Hormones; Proline; Protein Conformation; Thyrotropin-Releasing Hormone	1973
Carbon-13 NMR studies of peptide hormones and their components. Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222 Topics: Carbon Isotopes; Computers; Deuterium; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Fourier Analysis; Gonadotropin-Releasing Hormone; Hydrogen-Ion Concentration; Hypothalamus; Isomerism; Lysine; Magnetic Resonance Spectroscopy; Melanocyte-Stimulating Hormones; Oligopeptides; Oxytocin; Peptides; Peptides, Cyclic; Pituitary Hormone-Releasing Hormones; Proline; Structure-Activity Relationship; Thyrotropin-Releasing Hormone; Vasopressins	1973
1H nuclear magnetic resonance studies of thyrotropin releasing factor (TRF). FEBS letters, 1974, Jun-15, Volume: 42, Issue:3 Topics: Binding Sites; Deuterium; Dimethyl Sulfoxide; Glutamates; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Proline; Protein Binding; Protein Conformation; Silicon Dioxide; Temperature; Thyrotropin-Releasing Hormone	1974
Conformational mobility of the pyrrolidine ring of proline in peptides and peptide hormones as manifest in carbon 13 spin-lattice relaxation times. The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21 Topics: Amino Acid Sequence; Angiotensin II; Carbon Isotopes; Computers; Deuterium; Fourier Analysis; Gonadotropin-Releasing Hormone; Hormones; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Oligopeptides; Oxytocin; Peptides; Peptides, Cyclic; Pituitary Hormone-Releasing Hormones; Proline; Protein Conformation; Structure-Activity Relationship; Thyrotropin-Releasing Hormone; Time Factors; Vasopressins	1974
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton. The Journal of biological chemistry, 1971, Nov-25, Volume: 246, Issue:22 Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays	1971
13C magnetic resonance study of the ionization of N-acetyl-DL-proline in aqueous solution. Biochimica et biophysica acta, 1974, May-24, Volume: 343, Issue:3 Topics: Acetates; Calorimetry; Carbon Isotopes; Deuterium; Hydrogen-Ion Concentration; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Proline; Thermodynamics; Time Factors	1974
A novel approach for studies of the molecular conformations in flexible polypeptides. FEBS letters, 1974, Aug-01, Volume: 43, Issue:3 Topics: Alanine; Calorimetry; Carbon Isotopes; Deuterium; Dimethyl Sulfoxide; Evaluation Studies as Topic; Kinetics; Magnetic Resonance Spectroscopy; Methods; Oligopeptides; Peptides; Phenylalanine; Proline; Protein Conformation; Structure-Activity Relationship; Thermodynamics	1974
Conformational interconversions of the cyclic hexapeptide cyclo(Pro-Gly) 3 . Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:7 Topics: Butanols; Cesium; Chemical Phenomena; Chemistry; Chlorine; Cyclization; Cyclohexanes; Deuterium; Dimethyl Sulfoxide; Formates; Glycine; Hydrocarbons, Halogenated; Hydrogenation; Imines; Lithium; Magnetic Resonance Spectroscopy; Methane; Peptides; Peptides, Cyclic; Potassium; Proline; Protein Conformation; Rubidium; Sodium; Water	1972
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium. The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21 Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan	1974
Conformation of antamanide-sodium in solution. Biochemistry, 1973, Volume: 12, Issue:4 Topics: Amines; Antitoxins; Carbon Isotopes; Circular Dichroism; Cyanides; Deuterium; Glycine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Peptides, Cyclic; Phenylalanine; Proline; Protons; Sodium; Solutions; Spectrum Analysis; Temperature; Thiocyanates	1973
Study of nitrogen-15-labeled amino acids and peptides by nuclear magnetic resonance spectroscopy. Biochemistry, 1973, May-22, Volume: 12, Issue:11 Topics: Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Dipeptides; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Structural; Nitrogen Isotopes; Peptides; Proline; Protein Conformation; Protons; Stereoisomerism; Valinomycin	1973
Deuteron magnetic resonance studies on the microdynamical behavior of partially deuterated oxytocin with neurophysin. Journal of molecular biology, 1973, Sep-25, Volume: 79, Issue:3 Topics: Chromatography, Gel; Chromatography, Thin Layer; Circular Dichroism; Deuterium; Electrophoresis, Polyacrylamide Gel; Glycine; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Neurophysins; Oligopeptides; Oxytocin; Proline; Spectrophotometry, Ultraviolet	1973
Proposed conformations of oxytocin and selected analogs in dimethyl sulfoxide as deduced from proton magnetic resonance studies. Biochemistry, 1973, Dec-18, Volume: 12, Issue:26 Topics: Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Glycine; Magnetic Resonance Spectroscopy; Mathematics; Models, Structural; Oligopeptides; Oxytocin; Proline; Protein Conformation; Protons; Structure-Activity Relationship; Sulfhydryl Compounds; Temperature; Valine	1973
The inhibition of proline racemase by a transition state analogue: delta-1-pyrroline-2-carboxylate. Biochemical and biophysical research communications, 1974, Mar-25, Volume: 57, Issue:2 Topics: Amino Acid Isomerases; Binding Sites; Carboxylic Acids; Clostridium; Deuterium; Dithiothreitol; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Optical Rotation; Proline; Protein Binding; Protein Conformation; Pyrroles	1974
NMR investigations of proline and its derivatives. 3. A NMR method for estimating spectroscopic and conformational changes in prolyl-compounds: the Halpha PMR multiplet of proline. Biochemical and biophysical research communications, 1974, Jun-04, Volume: 58, Issue:3 Topics: Computers; Deuterium; Magnetic Resonance Spectroscopy; Mathematics; Models, Structural; Proline; Structure-Activity Relationship	1974
Solvent dependence of peptide carbonyl carbon chemical shifts and polypeptide secondary structure: the repeat tetrapeptide of elastin. Biochemical and biophysical research communications, 1974, Jul-10, Volume: 59, Issue:1 Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Carbon Isotopes; Deuterium; Dimethyl Sulfoxide; Elastin; Ethanol; Fluorine; Glycine; Magnetic Resonance Spectroscopy; Methanol; Peptides; Proline; Protein Binding; Protein Conformation; Solvents; Temperature; Valine	1974
Evidence for cis peptide bonds in copolypeptides of glycine and proline. Biochemistry, 1972, Apr-11, Volume: 11, Issue:8 Topics: Deuterium; Dimethyl Sulfoxide; Ethanol; Fluorine; Glycine; Isomerism; Magnetic Resonance Spectroscopy; Peptides; Proline; Protein Conformation; Stereoisomerism; Temperature; Thermodynamics	1972
Experimental and calculated conformational characteristics of the cyclic decapeptide antamanide. Biochemistry, 1971, Aug-17, Volume: 10, Issue:17 Topics: 1-Propanol; Alanine; Chemical Phenomena; Chemistry, Physical; Chloroform; Circular Dichroism; Deuterium; Dioxins; Ethanol; Fluorine; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Models, Chemical; Models, Structural; Peptides; Peptides, Cyclic; Phenylalanine; Proline; Protein Conformation; Ultraviolet Rays; Valine	1971
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives. Journal of chromatography, 1970, Aug-12, Volume: 50, Issue:3 Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine	1970
Purification and mechanism of action of proline racemase. Biochemistry, 1968, Volume: 7, Issue:11 Topics: Amides; Binding Sites; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Ion Exchange; Clostridium; Computers, Analog; Deuterium; Hot Temperature; Hydrogen-Ion Concentration; Iodoacetates; Isomerases; Proline; Sulfhydryl Compounds; Ultracentrifugation; Vibration	1968
Studies of the mechanism of action of D-proline reductase: the presence on covalently bound pyruvate and its role in the catalytic process. Archives of biochemistry and biophysics, 1969, Volume: 130, Issue:1 Topics: Amino Acid Oxidoreductases; Boron Compounds; Chromatography, Thin Layer; Clostridium; Colorimetry; Deuterium; Electrophoresis; Hydroxylamines; Iodoacetates; Lactates; Models, Chemical; Phenylhydrazines; Proline; Pyruvates; Tritium	1969
Fungal metabolites. XX. Effect of proline residue on the structure of ion-channel-forming peptide, trichosporin B-VIa. Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:7 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Deuterium; Fungal Proteins; Ion Channels; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Proline; Protein Structure, Secondary; Trichoderma	1995
Structure of a hydrophobically collapsed intermediate on the conformational folding pathway of ribonuclease A probed by hydrogen-deuterium exchange. Biochemistry, 1996, Sep-10, Volume: 35, Issue:36 Topics: Amides; Amino Acid Sequence; Animals; Cattle; Deuterium; Guanidine; Guanidines; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Ribonuclease, Pancreatic	1996
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide. European journal of biochemistry, 1996, Aug-15, Volume: 240, Issue:1 Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine	1996
Intramolecular assistance of cis/trans isomerization of the histidine-proline moiety. Biochemistry, 1997, Nov-11, Volume: 36, Issue:45 Topics: Angiotensin III; Catalysis; Deuterium; Histidine; Magnetic Resonance Spectroscopy; Oligopeptides; Proline; Protein Conformation; Protein Folding; Solvents; Stereoisomerism; Thyrotropin-Releasing Hormone	1997
Local control of peptide conformation: stabilization of cis proline peptide bonds by aromatic proline interactions. Biopolymers, 1998, Volume: 45, Issue:5 Topics: Deuterium; Kinetics; Molecular Conformation; Peptides; Phenylalanine; Proline; Protein Folding; Stereoisomerism; Thermodynamics; Tyrosine	1998
Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation. Journal of molecular biology, 1999, Jul-09, Volume: 290, Issue:2 Topics: Conserved Sequence; Deuterium; Disulfides; Guanidine; Humans; Hydrogen; Immunoglobulin Fragments; Immunoglobulin Variable Region; Isomerism; Kinetics; Mass Spectrometry; Mutation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Solubility; Spectrometry, Fluorescence; Thermodynamics	1999
Protein conformational stabilities can be determined from hydrogen exchange rates. Nature structural biology, 1999, Volume: 6, Issue:10 Topics: Deuterium; Deuterium Oxide; Hydrogen; Isomerism; Kinetics; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Ribonuclease T1; Temperature; Thermodynamics	1999
D/H amide kinetic isotope effects reveal when hydrogen bonds form during protein folding. Nature structural biology, 2000, Volume: 7, Issue:1 Topics: Amides; Amino Acid Substitution; Animals; Cytochrome c Group; Deuterium; Dimerization; Disulfides; DNA-Binding Proteins; Enzyme Stability; Fungal Proteins; Humans; Hydrogen Bonding; Isomerism; Kinetics; Models, Molecular; Proline; Protein Denaturation; Protein Folding; Protein Kinases; Protein Structure, Secondary; Proteins; Saccharomyces cerevisiae Proteins; Solvents; Thermodynamics; Ubiquitins; Water	2000
Direct evidence by H/D exchange and ESI-MS for transient unproductive domain interaction in the refolding of an antibody scFv fragment. Protein science : a publication of the Protein Society, 2000, Volume: 9, Issue:3 Topics: Deuterium; Hydrogen; Immunoglobulin Fragments; Immunoglobulin Variable Region; Kinetics; Mass Spectrometry; Proline; Protein Folding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Stereoisomerism	2000
Mechanistic studies on prolyl-4-hydroxylase: the vitamin C requiring uncoupled oxidation. Bioorganic & medicinal chemistry letters, 2000, Jul-17, Volume: 10, Issue:14 Topics: Amino Acid Sequence; Ascorbic Acid; Deuterium; Humans; Kinetics; Oligopeptides; Oxidation-Reduction; Procollagen; Procollagen-Proline Dioxygenase; Proline; Substrate Specificity	2000
HNCAN pulse sequences for sequential backbone resonance assignment across proline residues in perdeuterated proteins. Journal of biomolecular NMR, 2000, Volume: 18, Issue:4 Topics: Amino Acid Sequence; Cytochrome c Group; Deuterium; Magnetics; Multienzyme Complexes; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidoreductases; Proline; Proteins; Sensitivity and Specificity; Sulfurtransferases; Wolinella	2000
Effect of solvent on the cis-trans conformational equilibrium of a proline imide bond of short model peptides in solution. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2001, Volume: 57, Issue:6 Topics: Chloroform; Deuterium; Dimethyl Sulfoxide; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides; Proline; Protein Conformation; Solutions; Solvents	2001
Precursors of 2-acetyl-1-pyrroline, a potent flavor compound of an aromatic rice variety. Journal of agricultural and food chemistry, 2002, Mar-27, Volume: 50, Issue:7 Topics: Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Indicator Dilution Techniques; Nitrogen Isotopes; Ornithine; Oryza; Plant Leaves; Plant Structures; Proline; Pyrroles; Taste	2002
Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY. Biochemistry, 2002, Jun-25, Volume: 41, Issue:25 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Circular Dichroism; Crystallography, X-Ray; Deuterium; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuropeptide Y; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorylcholine; Proline; Protein Conformation; Protein Structure, Secondary; Protons; Rats; Receptors, Neuropeptide Y; Spin Labels; Thermodynamics	2002
Backbone dynamics and hydrogen exchange of Pseudomonas aeruginosa ferricytochrome c(551). Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2003, Volume: 8, Issue:1-2 Topics: Amino Acid Sequence; Bacterial Proteins; Cytochrome c Group; Cytochromes c; Deuterium; Hydrogen; Hydrogen Bonding; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Pseudomonas aeruginosa; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship	2003
HYDROXYPROLINE BIOSYNTHESIS: LOSS OF HYDROGEN DURING THE HYDROXYLATION OF PROLINE. Nature, 1964, Apr-18, Volume: 202 Topics: Biochemical Phenomena; Carbon Isotopes; Deuterium; Hydrogen; Hydroxylation; Hydroxyproline; Metabolism; Proline; Research; Tritium	1964
Quantitative observation of backbone disorder in native elastin. The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9 Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Deuterium; Elasticity; Elastin; Magnetic Resonance Spectroscopy; Proline; Protein Structure, Secondary; Spectrum Analysis; Thermodynamics; Water	2004
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:24 Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine	2003
Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion. Chemical communications (Cambridge, England), 2004, Jan-21, Issue:2 Topics: Amino Acid Sequence; Chlorides; Chloroform; Deuterium; Glycine; Oligopeptides; Peptide Fragments; Proline; Protein Binding	2004
Arginine synthesis does not occur during first-pass hepatic metabolism in the neonatal piglet. American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:6 Topics: Amino Acids; Ammonia; Animal Feed; Animals; Animals, Newborn; Arginine; Blood Urea Nitrogen; Deuterium; Enteral Nutrition; Liver; Male; Ornithine; Proline; Random Allocation; Swine; Urea	2005
Two separate and distinct syntheses of stereospecifically deuteriated samples of (2S)-proline. Organic & biomolecular chemistry, 2006, Apr-21, Volume: 4, Issue:8 Topics: Deuterium; Molecular Structure; Proline; Stereoisomerism	2006
Proline zwitterion dynamics in solution, glass, and crystalline state. Journal of the American Chemical Society, 2006, Oct-18, Volume: 128, Issue:41 Topics: Algorithms; Computer Simulation; Crystallization; Deuterium; Glass; Ions; Molecular Conformation; Peptides; Proline; Proteins; Solutions; Solvents; Spectrum Analysis, Raman; Surface Properties; Temperature; Water	2006
Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids. Journal of the American Chemical Society, 2006, Oct-18, Volume: 128, Issue:41 Topics: Amino Acid Sequence; Amino Acids; Carbon Isotopes; Computer Simulation; Deuterium; Glycine; Magnetic Resonance Spectroscopy; Models, Statistical; Molecular Sequence Data; Nitrogen Isotopes; Peptides; Proline; Protein Conformation; Protein Folding; Protein Structure, Secondary	2006
Enhanced stability of cis Pro-Pro peptide bond in Pro-Pro-Phe sequence motif. FEBS letters, 2007, Sep-18, Volume: 581, Issue:23 Topics: Amino Acid Sequence; Deuterium; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Phenylalanine; Proline; Protein Binding; Stereoisomerism	2007
Pockets of short-range transient order and restricted topological heterogeneity in the guanidine-denatured state ensemble of GED of dynamin. Biochemistry, 2007, Oct-23, Volume: 46, Issue:42 Topics: Amino Acid Sequence; Circular Dichroism; Cloning, Molecular; Deuterium; DNA, Complementary; Dynamin I; Escherichia coli; Guanidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Plasmids; Proline; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Temperature; Time Factors	2007
Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein. Journal of molecular biology, 2008, Jan-11, Volume: 375, Issue:2 Topics: Amyloid; Amyloid beta-Peptides; Cystatins; Deuterium; Dimerization; Escherichia coli; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Stereoisomerism; Time Factors	2008
Kinetic and mechanistic studies of proline-mediated direct intermolecular aldol reactions. Bioorganic & medicinal chemistry letters, 2009, Jul-15, Volume: 19, Issue:14 Topics: Aldehydes; Catalysis; Deuterium; Ketones; Kinetics; Proline	2009
2H-DNP-enhanced 2H-13C solid-state NMR correlation spectroscopy. Physical chemistry chemical physics : PCCP, 2010, Jun-14, Volume: 12, Issue:22 Topics: Carbon Isotopes; Cyclic N-Oxides; Deuterium; Nuclear Magnetic Resonance, Biomolecular; Proline; Propanols	2010
NMR investigations on the proline-catalyzed aldehyde self-condensation: Mannich mechanism, dienamine detection, and erosion of the aldol addition selectivity. The Journal of organic chemistry, 2011, May-06, Volume: 76, Issue:9 Topics: Acetaldehyde; Aldehydes; Alkenes; Amines; Catalysis; Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Proline; Stereoisomerism; Substrate Specificity	2011
Solvent and conformation dependence of amide I vibrations in peptides and proteins containing proline. The Journal of chemical physics, 2011, Dec-21, Volume: 135, Issue:23 Topics: Algorithms; Amides; Animals; Deuterium; Humans; Molecular Dynamics Simulation; Peptides; Proline; Protein Conformation; Proteins; Solvents; Spectrophotometry, Infrared; Vibration; Water	2011
2H-13C HETCOR MAS NMR for indirect detection of 2H quadrupole patterns and spin-lattice relaxation rates. Journal of magnetic resonance (San Diego, Calif. : 1997), 2013, Volume: 226 Topics: Alanine; Algorithms; Deuterium; Electromagnetic Fields; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline	2013
Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons. Journal of the American Society for Mass Spectrometry, 2013, Volume: 24, Issue:6 Topics: Deuterium; Gases; Ions; Models, Molecular; Oligopeptides; Proline; Protons; Tandem Mass Spectrometry	2013
Elucidating proline dynamics in spider dragline silk fibre using 2H-13C HETCOR MAS NMR. Chemical communications (Cambridge, England), 2014, May-14, Volume: 50, Issue:37 Topics: Amino Acid Sequence; Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Deuterium; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Structure, Secondary; Silk; Spiders	2014
Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors. Bioorganic & medicinal chemistry letters, 2016, 10-01, Volume: 26, Issue:19 Topics: Amides; Animals; Biological Availability; Class I Phosphatidylinositol 3-Kinases; Deuterium; Enzyme Inhibitors; Kinetics; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Rats; Thiazoles; Urea	2016
Stable Isotope Labeling of Prodiginines and Serratamolides Produced by Serratia marcescens Directly on Agar and Simultaneous Visualization by Matrix-Assisted Laser Desorption/Ionization Imaging High-Resolution Mass Spectrometry. Analytical chemistry, 2018, 11-20, Volume: 90, Issue:22 Topics: Agar; Ammonium Chloride; Carbon Isotopes; Depsipeptides; Deuterium; Isotope Labeling; Methionine; Nitrogen Isotopes; Prodigiosin; Proline; Serine; Serratia marcescens; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2018
Catalysis of Hydrogen-Deuterium Exchange Reactions by 4-Substituted Proline Derivatives. The Journal of organic chemistry, 2019, 02-01, Volume: 84, Issue:3 Topics: Anions; Catalysis; Deuterium; Fluorine; Hydrogen; Isomerism; Ketones; Kinetics; Proline	2019
Abnormal (Hydroxy)proline Deuterium Content Redefines Hydrogen Chemical Mass. Journal of the American Chemical Society, 2022, 02-16, Volume: 144, Issue:6 Topics: Animals; Anseriformes; Bone and Bones; Collagen; Deuterium; Fibroblasts; Humans; Hydroxyproline; Mice; Proline; Seals, Earless; Ursidae	2022