proline and beta-proline

proline has been researched along with beta-proline in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's8 (38.10)29.6817
2010's11 (52.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boxer, PA; Bruns, RF; Drummond, JT; Johnson, G1
Gellman, SH; Huck, BR; Langenhan, JM1
Cardillo, G; Gentilucci, L; Qasem, AR; Sgarzi, F; Spampinato, S1
Aguilar, MI; Lew, R; Perlmutter, P; Smith, AI; Steer, D1
Calienni, M; Cardillo, G; Gentilucci, L; Murari, G; Qasem, AR; Spampinato, S; Tolomelli, A1
Cannon, JF; Guo, L; Li, G; Liu, J; Timmons, C1
Chemla, F; Denes, F; Perez-Luna, A1
Albertshofer, K; Barbas, CF; Cheong, PH; Garcia-Delgado, N; Houk, KN; Imai, M; Mifsud, M; Mitsumori, S; Tanaka, F; Utsumi, N; Zhang, H1
Adamek, E; Bilska, M; Jankowski, S; Katarzyńska, J; Mazur, A; Zabrocki, J; Zimecki, M1
Armstrong, A; Bhonoah, Y; White, AJ1
Gentilucci, L; Mosconi, E; Paradisi, E; Tolomelli, A; Viola, A1
Carbery, DR; Carswell, EL; Harker, WR1
Banerjee, S; Faulkner, C; Masterson, DS; Smith, J1
Císařová, I; Jahn, U; Kapras, V; Pohl, R1
Kawahata, M; Liu, X; Ohwada, T; Otani, Y; Wang, S; Yamaguchi, K1
Bräse, S; Churakov, AV; Guh, JH; Ivantcova, PM; Kudryavtsev, KV; Polshakov, VI; Yu, CC; Zefirov, NS1
Arutyunyan, AM; Bräse, S; Churakov, AV; Dyuba, AV; Guh, JH; Howard, JA; Ivantcova, PM; Kudryavtsev, KV; Muhle-Goll, C; Sokolov, MN; Yu, CC; Zefirov, NS1
Bulbarelli, A; Cocuzza, C; Ferrazzano, L; Lombardo, M; Lonati, E; Musumeci, R; Tolomelli, A; Viola, A1
Kitao, A; Ohwada, T; Otani, Y; Watanabe, S1
Kawahata, M; Nara, M; Ohki, R; Ohwada, T; Otani, Y; Sada, A; Su, A; Wang, S; Yamaguchi, K; Zhai, L1
Liu, X; Ohki, R; Ohwada, T; Otani, Y; Sada, A; Sayama, M; Su, A; Wang, S; Zhai, L1

Other Studies

21 other study(ies) available for proline and beta-proline

ArticleYear
Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: Animals; beta-Alanine; Binding, Competitive; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Proline; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine

1992
Non-hydrogen-bonded secondary structure in beta-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers.
    Organic letters, 1999, Dec-02, Volume: 1, Issue:11

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Nipecotic Acids; Peptides; Proline; Protein Structure, Secondary; Pyrrolidines; Spectrophotometry, Ultraviolet

1999
Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.
    Journal of medicinal chemistry, 2002, Jun-06, Volume: 45, Issue:12

    Topics: Animals; Binding, Competitive; Brain; Carboxypeptidases; Cathepsin A; CD13 Antigens; Chymotrypsin; Cyclic AMP; Hydrolysis; In Vitro Techniques; Oligopeptides; Proline; Radioligand Assay; Rats; Receptors, Opioid, mu; Stereoisomerism; Tumor Cells, Cultured

2002
Inhibitors of metalloendopeptidase EC 3.4.24.15 and EC 3.4.24.16 stabilized against proteolysis by the incorporation of beta-amino acids.
    Biochemistry, 2002, Sep-03, Volume: 41, Issue:35

    Topics: Amino Acid Substitution; Amino Acids; Animals; beta-Alanine; Drug Stability; Glycine; Hydrolysis; Metalloendopeptidases; Molecular Mimicry; Neprilysin; Oligopeptides; Peptide Biosynthesis; Proline; Protease Inhibitors; Rats; Structure-Activity Relationship; Tyrosine

2002
Antinociception by a peripherally administered novel endomorphin-1 analogue containing beta-proline.
    European journal of pharmacology, 2003, May-23, Volume: 469, Issue:1-3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Male; Mice; Oligopeptides; Pain Measurement; Proline

2003
Asymmetric halo-Mannich-type reaction provides access to pyrrolidines and beta-proline derivatives.
    The Journal of organic chemistry, 2005, Sep-16, Volume: 70, Issue:19

    Topics: Magnetic Resonance Spectroscopy; Mannich Bases; Proline; Pyrrolidines

2005
Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.
    The Journal of organic chemistry, 2007, Jan-19, Volume: 72, Issue:2

    Topics: Cyclization; Molecular Conformation; Proline; Stereoisomerism

2007
Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol.
    Journal of the American Chemical Society, 2008, Jan-23, Volume: 130, Issue:3

    Topics: Aldehydes; Catalysis; Imines; Ketones; Molecular Structure; Proline; Pyrrolidines; Stereoisomerism

2008
Synthesis and immunosuppressive activity of new cyclolinopeptide A analogs modified with beta-prolines.
    Journal of peptide science : an official publication of the European Peptide Society, 2008, Volume: 14, Issue:12

    Topics: Amino Acid Sequence; Antibody Formation; Cell Line, Tumor; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Sequence Data; Peptides, Cyclic; Proline

2008
Constrained beta-proline analogues in organocatalytic aldol reactions: the influence of acid geometry.
    The Journal of organic chemistry, 2009, Jul-17, Volume: 74, Issue:14

    Topics: Aldehydes; Catalysis; Hydrogen-Ion Concentration; Molecular Structure; Proline; Stereoisomerism

2009
A straightforward route to enantiopure 2-substituted-3,4-dehydro-β-proline via ring closing metathesis.
    Amino acids, 2011, Volume: 41, Issue:3

    Topics: Amination; Amino Acids, Cyclic; Carbonates; Esters; Iridium; Peptidomimetics; Proline; Pyrroles; Stereoisomerism

2011
Si-free enolate Claisen rearrangements of enamido substrates.
    Organic & biomolecular chemistry, 2012, Feb-21, Volume: 10, Issue:7

    Topics: Esters; Proline; Stereoisomerism

2012
A stereoselective cyclization strategy for the preparation of γ-lactams and their use in the synthesis of α-methyl-β-proline.
    The Journal of organic chemistry, 2012, Dec-07, Volume: 77, Issue:23

    Topics: Amino Acids; Cyclization; Esters; Lactams; Molecular Structure; Proline; Stereoisomerism

2012
Asymmetric domino aza-Michael addition/[3 + 2] cycloaddition reactions as a versatile approach to α,β,γ-triamino acid derivatives.
    Organic letters, 2014, Feb-21, Volume: 16, Issue:4

    Topics: Amino Acids; Cycloaddition Reaction; Molecular Structure; Peptides; Proline; Pyrazoles; Pyrroles; Stereoisomerism

2014
Robust trans-amide helical structure of oligomers of bicyclic mimics of β-proline: impact of positional switching of bridgehead substituent on amide cis-trans equilibrium.
    The Journal of organic chemistry, 2014, Jun-06, Volume: 79, Issue:11

    Topics: Amides; Amino Acids; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides; Proline; Protein Conformation; Stereoisomerism

2014
Structural studies and anticancer activity of a novel class of β-peptides.
    Chemistry, an Asian journal, 2015, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cycloaddition Reaction; Humans; Membrane Potential, Mitochondrial; Peptides; Proline; Protein Conformation; Stereoisomerism

2015
Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers.
    Organic letters, 2015, Dec-18, Volume: 17, Issue:24

    Topics: Antineoplastic Agents; Azo Compounds; Catalysis; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Humans; Male; Menthol; Molecular Structure; Proline; Protein Structure, Secondary; Stereoisomerism; Thiosemicarbazones

2015
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Anti-Bacterial Agents; Catalytic Domain; Enterococcus faecalis; Hep G2 Cells; Humans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Proline; Staphylococcus aureus; Structure-Activity Relationship

2016
Molecular Dynamics Study of Nitrogen-Pyramidalized Bicyclic β-Proline Oligomers: Length-Dependent Convergence to Organized Structures.
    The journal of physical chemistry. B, 2017, 01-12, Volume: 121, Issue:1

    Topics: Molecular Dynamics Simulation; Molecular Structure; Nitrogen; Proline; Pyrimidines

2017
Overall Shape Constraint of Alternating α/β-Hybrid Peptides Containing Bicyclic β-Proline.
    Organic letters, 2019, 10-04, Volume: 21, Issue:19

    Topics: Cell Cycle Proteins; Crystallography, X-Ray; Humans; Molecular Dynamics Simulation; Peptides; Proline; Protein Binding; Protein Structure, Secondary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53

2019
Non-naturally Occurring Helical Molecules Can Interfere with p53-MDM2 and p53-MDMX Protein-Protein Interactions.
    Chemical & pharmaceutical bulletin, 2019, Volume: 67, Issue:10

    Topics: Cell Cycle Proteins; Humans; Molecular Structure; Nuclear Proteins; Proline; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53

2019