proline has been researched along with act-462206 in 1 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aissaoui, H; Boss, C; Brotschi, C; Dietrich, H; Gatfield, J; Heidmann, B; Jenck, F; Roch-Brisbare, C; Siegrist, R; Sifferlen, T; Steiner, MA; Treiber, A; von Raumer, M; Williams, JT | 1 |
1 other study(ies) available for proline and act-462206
| Article | Year |
|---|---|
Structure-activity relationship, biological, and pharmacological characterization of the proline sulfonamide ACT-462206: a potent, brain-penetrant dual orexin 1/orexin 2 receptor antagonist.
Topics: Animals; Blood-Brain Barrier; Brain; Dogs; Half-Life; Humans; Madin Darby Canine Kidney Cells; Male; Neurotransmitter Agents; Orexin Receptor Antagonists; Orexin Receptors; Proline; Pyrrolidines; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Sulfonamides | 2014 |